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2022

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Return Of Floodplain Connectivity And Concurrent Macroinvertebrate Community Response Following Wetland Restoration In Western Kentucky, Christiane M. Soldo Ms. Jan 2022

Return Of Floodplain Connectivity And Concurrent Macroinvertebrate Community Response Following Wetland Restoration In Western Kentucky, Christiane M. Soldo Ms.

Murray State Theses and Dissertations

Wetlands improve the quality of our nation’s streams, rivers, and lakes, and they support a diverse assemblage of plant and animal species. The U.S. Department of Agriculture Natural Resources Conservation Service (USDA-NRCS) is responsible for administering the Wetland Reserve Program (WRP), a multi-billion-dollar effort to restore wetlands throughout the nation. Each year, WRP enrolls thousands of acres of private farmland into conservation easements with the goal of improving water quality and creating wildlife habitat. Hydrological modification structures, such as levee breaks, ditch plugs, or shallow water areas are constructed on easements to create wetlands by improving water retention and returning …


Habitat Use And Diel Movements Of Silver Carp Hypophthalmichthys Molitrix In Two Southeastern Reservoirs, Levi Umland Jan 2022

Habitat Use And Diel Movements Of Silver Carp Hypophthalmichthys Molitrix In Two Southeastern Reservoirs, Levi Umland

Murray State Theses and Dissertations

Bigheaded carp have spread rampantly throughout the Mississippi watershed and continue to spread by navigating through rivers, locks, and dams. The long-term effects these species will have on our ecosystems and natural resources is unknown. Their movements, behavior, and general seasonal patterns are well studied within rivers. However, their movements and behavior within reservoirs is poorly understood due to their initial numbers within reservoirs being lower than in rivers. To address this gap, I investigated the distribution and movement rates of Silver Carp within two reservoirs, Kentucky Reservoir and Barkley Reservoir, and possible correlative variables, including wind, temperature, residency, sex, …


Isocaloric Low Protein Diet In A Mouse Model For Vanishing White Matter Does Not Impact Isr Deregulation In Brain, But Reveals Isr Deregulation In Liver, Lisanne E. Wisse, Denise Visser, Timo J. Ter Braak, Abdellatif Bakkali, Eduard A. Struys, Christopher D. Morrison, Marjo S. Van Der Knaap, Truus E.M. Abbink Jan 2022

Isocaloric Low Protein Diet In A Mouse Model For Vanishing White Matter Does Not Impact Isr Deregulation In Brain, But Reveals Isr Deregulation In Liver, Lisanne E. Wisse, Denise Visser, Timo J. Ter Braak, Abdellatif Bakkali, Eduard A. Struys, Christopher D. Morrison, Marjo S. Van Der Knaap, Truus E.M. Abbink

Division of Basic Science Faculty Publications

Objective: Vanishing white matter (VWM) is a genetic brain white matter disorder caused by mutations in eIF2B. eIF2B is central in the integrated stress response (ISR), during which its activity is inhibited by various cellular stresses. VWM is a chronic progressive disease with episodes of rapid neurological deterioration provoked by stresses. VWM patients and VWM mouse models show ISR deregulation in brain, correlating with chronic disease development. ISR inhibition ameliorates the chronic disease in VWM mice. The subacute deteriorations have not been modeled yet. We hypothesized that ISR activation could worsen disease progression in mice and model the episodic neurological …


Obesity: Understanding And Achieving A Healthy Weight, George A. Bray, Catherine M. Champagne Jan 2022

Obesity: Understanding And Achieving A Healthy Weight, George A. Bray, Catherine M. Champagne

Population and Public Health Science Faculty Publications

Obesity is a chronic, relapsing, stigmatized disease process that is increasing in prevalence, affecting both adults and children. It is the result of a small positive energy imbalance from too much food or too little activity. These underlying causes are influenced by many environmental factors. The food we eat is more than “calories,” and focusing on calories alone may not be as productive as focusing on patterns of eating and the role of sugar and fat in the diet. Obesity increases the risk of many diseases and shortens life span, and weight loss provides benefits in reducing health risks and …


Obesity, Body Composition, And Sex Hormones: Implications For Cardiovascular Risk, Prachi Singh, Naima Covassin, Kara Marlatt, Kishore M. Gadde, Steven B. Heymsfield Jan 2022

Obesity, Body Composition, And Sex Hormones: Implications For Cardiovascular Risk, Prachi Singh, Naima Covassin, Kara Marlatt, Kishore M. Gadde, Steven B. Heymsfield

Clinical Research Faculty Publications

Cardiovascular disease (CVD) continues to be the leading cause of death in adults, highlighting the need to develop novel strategies to mitigate cardiovascular risk. The advancing obesity epidemic is now threatening the gains in CVD risk reduction brought about by contemporary pharmaceu-tical and surgical interventions. There are sex differences in the development and outcomes of CVD; premenopausal women have significantly lower CVD risk than men of the same age, but women lose this advantage as they transition to menopause, an observation suggesting potential role of sex hormones in determining CVD risk. Clear differences in obesity and regional fat distribution among …


Turning The Tides: An Inoculation Theory And Theory Of Planned Behavior Approach To Developing Mental Health Help-Seeking Interventions For Gen Z, Sarah Ann Geegan Jan 2022

Turning The Tides: An Inoculation Theory And Theory Of Planned Behavior Approach To Developing Mental Health Help-Seeking Interventions For Gen Z, Sarah Ann Geegan

Theses and Dissertations--Communication

Extensive research, predating and during the COVID-19 pandemic, demonstrates the rising prevalence of anxiety and depression among Gen Z college students in the United States—findings which are accompanied by rising rates of suicide, the second leading cause of death among people aged 15-24. Although college campuses often offer mental health resources, the number of college students utilizing them is significantly less than the number of students reporting mental health challenges. A dearth of empirical evidence, focused on Gen Z specifically, exists as a basis for developing interventions to address this issue. This investigation addressed this gap through two component studies. …


A Content Analysis Of Reddit Comments Discussing Fibroadenoma Appraisal And Decision Making, Hayley Marie Kay Stahl Jan 2022

A Content Analysis Of Reddit Comments Discussing Fibroadenoma Appraisal And Decision Making, Hayley Marie Kay Stahl

Theses and Dissertations--Communication

Though fibroadenomas are clinically benign in most cases, clinical research suggests that these lesions can cause diagnosis-related physical health complications and psychological distress. However, this research is limited and should be investigated further. Thus, this study aimed to explore how patients appraise their fibroadenoma diagnosis uncertainty. Additionally, this study sought to determine if a correlation existed between appraisal and decision making as well as identify the factors that influence the most common treatment decision: removal. Data was retrieved from Reddit discussions for a content analysis. These discussions were then qualitatively analyzed using codebooks associated with this study’s research questions. Findings …


Decitizenizing Asian Pacific American Women, Shoba Sivaprasad Wadhia, Margaret Hu Jan 2022

Decitizenizing Asian Pacific American Women, Shoba Sivaprasad Wadhia, Margaret Hu

University of Colorado Law Review

The Page Act of 1875 excluded Asian women immigrants from entering the United States, presuming they were prostitutes. This presumption was tragically replicated in the 2021 Atlanta Massacre of six Asian and Asian American women, reinforcing the same harmful prejudices. This Article seeks to illuminate how the Atlanta Massacre is symbolic of larger forms of discrimination, including the harms of decitizenship. These harms include limited access to full citizenship rights due to legal barriers, restricted cultural and political power, and a lack of belonging. The Article concludes that these harms result from the structure of past and present immigration laws …


Liquid Biopsies To Occult Brain Metastasis, Asad Ur Rehman, Parvez Khan, Shailendra K. Maurya, Jawed A. Siddiqui, Juan A. Santamaria-Barria, Surinder K. Batra, Mohd W. Nasser Jan 2022

Liquid Biopsies To Occult Brain Metastasis, Asad Ur Rehman, Parvez Khan, Shailendra K. Maurya, Jawed A. Siddiqui, Juan A. Santamaria-Barria, Surinder K. Batra, Mohd W. Nasser

Journal Articles: Biochemistry & Molecular Biology

Brain metastasis (BrM) is a major problem associated with cancer-related mortality, and currently, no specific biomarkers are available in clinical settings for early detection. Liquid biopsy is widely accepted as a non-invasive method for diagnosing cancer and other diseases. We have reviewed the evidence that shows how the molecular alterations are involved in BrM, majorly from breast cancer (BC), lung cancer (LC), and melanoma, with an inception in how they can be employed for biomarker development. We discussed genetic and epigenetic changes that influence cancer cells to breach the blood-brain barrier (BBB) and help to establish metastatic lesions in the …


Modulation Of Arginase-2 Mrna Levels By Ω-3 Pufas And Aspirin In Asthmatic Human Lung Fibroblasts, Vamsee K Duggirala, Kyla Geary, Donald Hasenmayer, Farzaneh Daghigh Jan 2022

Modulation Of Arginase-2 Mrna Levels By Ω-3 Pufas And Aspirin In Asthmatic Human Lung Fibroblasts, Vamsee K Duggirala, Kyla Geary, Donald Hasenmayer, Farzaneh Daghigh

PCOM Scholarly Works

Airway remodeling (AR) increases disease severity, and morbidity of asthmatic patients by contributing to irreversible airflow obstruction and progressive declines in lung function. Arginase isoenzymes and the downstream enzymes ornithine decarboxylase (ODC) and ornithine aminotransferase (OAT) have been implicated in the hyperplastic and fibrotic changes of AR, respectively. Omega-3 polyunsaturated fatty acids (ω-3 PUFAs) and resolvin metabolites have anti-AR effects, but whether they are mediated through the arginase pathway is unclear. Our study intended to determine the effects of the ω-3 PUFAs eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), resolvin D1 (RvD1), TH1 cytokines, acetylsalicylic acid (ASA), cAMP, …


Using Adaptive Governance To Protect Oregon’S Water Resources, Lauren Butz Jan 2022

Using Adaptive Governance To Protect Oregon’S Water Resources, Lauren Butz

Lewis & Clark Law Review

Over 30 years ago, Oregon adopted the innovative In-Stream Water Rights Act, which introduced new regulatory tools and incentives for encouraging efficient water consumption, and paved the way for the emergence of water trusts. However, Oregon’s water resources are under increasing strain as the state faces the challenges of over-appropriation and climate change. New solutions are needed to augment the existing regulatory framework. This Comment draws on the principles of adaptive governance and ecological resilience to formulate possible legal solutions to help the state adapt to increasing demands for water, proposing that Oregon leverage corporate social responsibility to encourage investments …


Step-Parent As Fiduciary, Ruth Zafran Jan 2022

Step-Parent As Fiduciary, Ruth Zafran

Lewis & Clark Law Review

Does a step-parent have any obligations toward the non-resident legal parent of the child? To date, the law has been silent on this point, and the scholarship has paid little, if any, attention to it. This Article argues that the conceptual framework of fiduciary enables us to recognize, both conceptually and legally, the relationship between the step-parent and the non-resident legal parent (who, generally speaking, spends less time with the child on a day-to-day basis). The aim of this fiduciary duty is to protect the more vulnerable party (in this specific context, the non-resident legal parent) from the more powerful …


Trojan Zebra: Unmasking Bostock’S Potential To Undermine Lgbtq+ Protections, James E.A. Rehwaldt Jan 2022

Trojan Zebra: Unmasking Bostock’S Potential To Undermine Lgbtq+ Protections, James E.A. Rehwaldt

Lewis & Clark Law Review

Engaging with the methodological framework endorsed by the Supreme Court’s holding and rejected by the dissents in Bostock v. Clayton County, this Comment critically examines both the limited scope and potential misuses of the Court’s decision recognizing protection against employment discrimination for gay, lesbian, and transgender individuals under Title VII of the Civil Rights Act.


Protecting The Sublette Antelope Migration: An Analysis Of The Evolution Of The Legal Tools Employed To Protect The Sublette Antelope Herd From Fencing Obstructions, Colin Reynolds Jan 2022

Protecting The Sublette Antelope Migration: An Analysis Of The Evolution Of The Legal Tools Employed To Protect The Sublette Antelope Herd From Fencing Obstructions, Colin Reynolds

Lewis & Clark Law Review

A biological marvel of the natural world, each year a small herd of pronghorn antelope—called the Sublette herd—migrate over 300 miles through a mix of public and private land in Wyoming. The Sublette herd’s annual movement constitutes one of the largest remaining “big game” migrations within the continental United States. Unfortunately, this migration faces an increasing number of obstacles threatening its long-term viability; chief among them being fencing obstacles. This Comment examines the evolution of the legal tools the federal government, the state of Wyoming, and everyday citizens can use to protect the Sublette herd’s migration.


ปัจจัยคัดสรรที่สัมพันธ์กับคุณภาพการนอนหลับในผู้ป่วยโรคหัวใจขาดเลือดเฉียบพลัน, ยศพันธุ์ นามสงค์, สุนิดา ปรีชาวงษ์ Jan 2022

ปัจจัยคัดสรรที่สัมพันธ์กับคุณภาพการนอนหลับในผู้ป่วยโรคหัวใจขาดเลือดเฉียบพลัน, ยศพันธุ์ นามสงค์, สุนิดา ปรีชาวงษ์

Journal of Nursing Research, Innovation, and Health

วัตถุประสงค์: 1.ศึกษาคุณภาพการนอนหลับในผู้ป่วยโรคหัวใจขาดเลือดเฉียบพลัน  2.ศึกษาความสัมพันธ์ระหว่างปัจจัยคัดสรร ได้แก่ ระดับความรุนแรงของอาการเจ็บหน้าอก ภาวะซึมเศร้า ความวิตกกังวล สถานะการสูบบุหรี่ อาการเหนื่อยล้า กับคุณภาพการนอนหลับ

รูปแบบการวิจัย: การวิจัยเชิงหาความสัมพันธ์

วิธีดำเนินการวิจัย: กลุ่มตัวอย่าง คือ ผู้ป่วยโรคหัวใจขาดเลือดเฉียบพลันอายุ 18 ปีขึ้นไป จำนวน 152 คน ซึ่งคัดเลือกแบบเฉพาะเจาะจง จากโรงพยาบาลระดับตติยภูมิสองแห่งในกรุงเทพมหานคร ตามเกณฑ์การคัดเข้า เครื่องมือที่ใช้ ได้แก่ แบบประเมินความรุนแรงของอาการเจ็บหน้าอก แบบสอบถามภาวะซึมเศร้า แบบประเมินความวิตกกังวล แบบประเมินอาการเหนื่อยล้า และแบบวัดคุณภาพการนอนหลับ  ซึ่งมีค่าสัมประสิทธิ์สหสัมพันธ์แอลฟาครอนบาค เท่ากับ 1.00, 0.76, 0.70, 0.92 และ 0.96  ตามลำดับ วิเคราะห์ข้อมูลด้วยสถิติเชิงบรรยาย และทดสอบความสัมพันธ์ด้วยสถิติสหสัมพันธ์เพียร์สัน

ผลการวิจัย: 1. กลุ่มตัวอย่างร้อยละ 84.9 มีคุณภาพการนอนหลับดี 2.ความวิตกกังวล สถานะการสูบบุหรี่ มีความสัมพันธ์ทางลบกับคุณภาพการนอนหลับ (r= -.197, -.175; p< .05) อาการเหนื่อยล้า ภาวะซึมเศร้ามีความสัมพันธ์ทางลบกับคุณภาพการนอนหลับ (r= -.440, -.528,  ; p< .01) และระดับความรุนแรงของอาการเจ็บหน้าอกไม่มีความสัมพันธ์กับคุณภาพการนอนหลับ

สรุป: การประเมินปัจจัยต่าง ๆ ที่ส่งผลต่อคุณภาพการนอนของผู้ป่วยโรคหัวใจขาดเลือดเฉียบพลัน เช่น ความวิตกกังวล สถานะการสูบบุหรี่ อาการเหนื่อยล้า ภาวะซึมเศร้า อย่างครอบคลุม จะช่วยให้พยาบาลสามารถวางแผนการดูแลและหาแนวทางการป้องกันการเกิดภาวะแทรกซ้อนในอนาคตได้


ปัจจัยคัดสรรที่สัมพันธ์กับภาวะซึมเศร้าของผู้ต้องขัง ติดเมทแอมเฟตามีน, วราภรณ์ กันธิยะ, เพ็ญพักตร์ อุทิศ Jan 2022

ปัจจัยคัดสรรที่สัมพันธ์กับภาวะซึมเศร้าของผู้ต้องขัง ติดเมทแอมเฟตามีน, วราภรณ์ กันธิยะ, เพ็ญพักตร์ อุทิศ

Journal of Nursing Research, Innovation, and Health

วัตถุประสงค์: เพื่อศึกษาภาวะซึมเศร้าของผู้ต้องขังติดเมทแอมเฟตามีน และความสัมพันธ์ระหว่างปัจจัยคัดสรรกับภาวะซึมเศร้าของผู้ต้องขังติดเมทแอมเฟตามีน

รูปแบบการวิจัย: การวิจัยแบบพรรณนาเชิงหาความสัมพันธ์

วิธีดำเนินการวิจัย: กลุ่มตัวอย่าง คือ ผู้ต้องขังติดเมทแอมเฟตามีน อายุ 18-59 ปี ในเรือนจำ/ทัณฑสถานเขตภาคเหนือตอนบน โดยวิธีการสุ่มตัวอย่างแบบชั้นภูมิ ได้กลุ่มตัวอย่างจำนวน 165 ราย เครื่องมือที่ใช้ในการวิจัย คือ 1) แบบคัดกรองและส่งต่อผู้ป่วยที่ใช้ยาและสารเสพติดเพื่อรับการบำบัดรักษา กระทรวงสาธารณสุข (บคก.กสธ.) V.2 2) แบบประเมินอาการทางจิต 3) แบบสอบถามข้อมูลส่วนบุคคลของผู้ต้องขังติดเมทแอมเฟตามีน 4) แบบสอบถามวัดการเผชิญความเครียด 5) แบบสอบถามวัดการเห็นคุณค่าในตนเอง 6) แบบสอบถามวัดการตีตราตนเอง 7) แบบสอบถามวัดการสนับสนุนทางสังคม และ 8) แบบประเมินภาวะซึมเศร้า เครื่องมือชุดที่ 2 และ 4-8 มีค่าความเที่ยง สัมประสิทธิ์อัลฟาของครอนบาค เท่ากับ .82, .87, .86, .82, .83 และ .91 ตามลำดับ วิเคราะห์ข้อมูลด้วยสถิติเชิงบรรยาย และทดสอบความสัมพันธ์ด้วยสถิติไคสแควร์ สหสัมพันธ์พอยท์ไบซีเรียล และสหสัมพันธ์เพียร์สัน

ผลการวิจัย: 1) ผู้ต้องขังติดเมทแอมเฟตามีนส่วนใหญ่ คิดเป็นร้อยละ 33.9 มีภาวะซึมเศร้าในระดับ    ปานกลาง 2) การเผชิญความเครียด แบบมุ่งจัดการกับปัญหาโดยใช้ความสามารถของตนเอง แบบมุ่งจัดการกับปัญหาโดยอาศัยแหล่งสนับสนุนอื่น ๆ และแบบหลีกเลี่ยงปัญหา มีความสัมพันธ์กับภาวะซึมเศร้าของผู้ต้องขังติดเมทแอมเฟตามีน (c2= 94.23; p<.05) 3) ระยะเวลาการต้องโทษ และการตีตราตนเอง มีความสัมพันธ์ทางบวกกับภาวะซึมเศร้าของผู้ต้องขังติดเมทแอมเฟตามีน (r = .446 และ .340; p<.05) 4) อายุ การเห็นคุณค่าในตนเอง และการสนับสนุนทางสังคม มีความสัมพันธ์ทางลบกับภาวะซึมเศร้าของผู้ต้องขังติดเมทแอมเฟตามีน (r = -.292, -.404 และ -.396; p<.05)

สรุป: การพยาบาลที่เหมาะสมกับผู้ต้องขังติดเมทแอมเฟตามีนควรมีการคัดกรองโดยใช้แบบประเมิน
และติดตามอย่างต่อเนื่อง เพื่อให้การดูแลที่เหมาะสมโดยคำนึงถึงปัจจัยต่าง ๆ ที่พบว่าสัมพันธ์กับอาการนี้


Who Are You Protecting?: A Feminist Analysis Of Gay And Trans Panic Defense Bans, How They Are Defined, And Who They Protect, Tyler S. Sesker Jan 2022

Who Are You Protecting?: A Feminist Analysis Of Gay And Trans Panic Defense Bans, How They Are Defined, And Who They Protect, Tyler S. Sesker

Undergraduate Honors Theses

As of April 2022, sixteen U.S. states ban Gay panic and Trans panic criminal defenses. These state-law prohibitions stemmed from several high-profile murder trials, focusing on the identity of the decedent, including the killings of Matthew Shepard and Latisha King. Between 1970 and 2020, criminal defenses interrogating the gender identity or sexual identity of victims of violence were used at least 104 times, with nearly a third of those cases resulting in reduced criminal charges and penalties. Today, in thirty-four states, the same tactics remain legal. Applying a feminist and outsider legal lens, this study engages in a textual analysis …


Impacts Of Some Metal Ions On Glutathione S-Transferase In The Liver Of Chalcalburnus Tarichi: An Endemic Species Of Lake Van, Muhammet Serhat Özaslan, Mehmet Çi̇ftci̇ Jan 2022

Impacts Of Some Metal Ions On Glutathione S-Transferase In The Liver Of Chalcalburnus Tarichi: An Endemic Species Of Lake Van, Muhammet Serhat Özaslan, Mehmet Çi̇ftci̇

Turkish Journal of Chemistry

Glutathione-S-transferase (GSTs) is a multifunctional enzyme that provides homeostasis by catalyzing the first step of the formation of mercapturic acid, the end product in detoxification metabolism. They can prevent reactive electrophilic compounds from harming the body by covalently binding the same type of compounds to each other. In this study, we determined the in vitro inhibitory effects of metal ions such as Cu2+, Cd2+, Ag+, and Co2+ on GST enzyme activity. For this aim, GST was purified from C. tarichi Pallas liver with 37.36% yield and 29.304 EU/mg specific activity using the chromatographic method. The Vmax values of liver GST …


Preparation And Characterisation Of Ethambutol With Β-Cyclodextrin: A Comprehensive Molecular Insight Into Host-Guest Interaction, Soen Qeng Goh, Qiao Hui Chan, Rohana Adnan, Nurul Yani Rahim Jan 2022

Preparation And Characterisation Of Ethambutol With Β-Cyclodextrin: A Comprehensive Molecular Insight Into Host-Guest Interaction, Soen Qeng Goh, Qiao Hui Chan, Rohana Adnan, Nurul Yani Rahim

Turkish Journal of Chemistry

The increase in new cases of drug resistance to first-line drugs such as ethambutol (ETB) makes it necessary to develop improvements for antituberculosis drugs. A new method for improving the bioavailability of active pharmaceutical ingredient (API) was investigated for preventing drug resistance and side-effects of antituberculosis drugs. In this study, an antituberculosis drug delivery system using β-cyclodextrin (β-CD) as the supramolecular carrier of ETB was prepared using the kneading method. The inclusion behaviour of β-CD/ETB inclusion complex in solid and liquid state was investigated. The inclusion complex was characterized using Fourier transform infrared spectroscopy, thermogravimetric analysis, nuclear magnetic resonance (NMR) …


Global Climate Governance In 3d: Mainstreaming Geoengineering Within A Unified Framework, Gabriel Weil Jan 2022

Global Climate Governance In 3d: Mainstreaming Geoengineering Within A Unified Framework, Gabriel Weil

Scholarly Works

The failure of conventional climate change mitigation to reduce climate-related risks to tolerable levels has spurred interest in more unconventional—and riskier—climate interventions. What currently sounds like science fiction could become a reality in the not-so-distant future: planes blasting particles into the sky to block the sun, vast deserts covered with mirrors, algae sucking carbon into the depths of the ocean. Scholars tend to lump all these unconventional climate measures together in a fuzzy category called “geoengineering,” and set them apart from conventional climate change mitigation. But the characteristics of climate interferences vary across three distinct dimensions, which the mitigation-geoengineering dichotomy …


Antagonistic Co-Contraction Can Minimize Muscular Effort In Systems With Uncertainty, Anne D. Koelewijn, Antonie J. Van Den Bogert Jan 2022

Antagonistic Co-Contraction Can Minimize Muscular Effort In Systems With Uncertainty, Anne D. Koelewijn, Antonie J. Van Den Bogert

Mechanical Engineering Faculty Publications

Muscular co-contraction of antagonistic muscle pairs is often observed in human movement, but it is considered inefficient and it can currently not be predicted in
simulations where muscular effort or metabolic energy are minimized. Here, we investigated the relationship between minimizing effort and muscular co-contraction
in systems with random uncertainty to see if muscular co-contraction can minimize effort in such system. We also investigated the effect of time delay in the muscle, by varying the time delay in the neural control as well as the activation time constant.We solved optimal control problems for a one-degree-of-freedom pendulum actuated by two identical …


Assessing Sex-Specific Circadian, Metabolic, And Cognitive Phenotypes In The Aβpp/Ps1 And Appnl-F/Nl-F Models Of Alzheimer's Disease., Jesse Britz, Emmanuel Ojo, Asmita Dhukhwa, Takashi Saito, Takaomi C Saido, Erin R Hascup, Kevin N Hascup, Shelley A Tischkau Jan 2022

Assessing Sex-Specific Circadian, Metabolic, And Cognitive Phenotypes In The Aβpp/Ps1 And Appnl-F/Nl-F Models Of Alzheimer's Disease., Jesse Britz, Emmanuel Ojo, Asmita Dhukhwa, Takashi Saito, Takaomi C Saido, Erin R Hascup, Kevin N Hascup, Shelley A Tischkau

Articles

BACKGROUND: Circadian disruption has long been recognized as a symptom of Alzheimer's disease (AD); however, emerging data suggests that circadian dysfunction occurs early on in disease development, potentially preceding any noticeable cognitive deficits.

OBJECTIVE: This study compares the onset of AD in male and female wild type (C57BL6/J), transgenic (AβPP/PS1), and knock-in (APPNL-F/NL-F) AD mouse models from the period of plaque initiation (6 months) through 12 months.

METHODS: Rhythmic daily activity patterns, glucose sensitivity, cognitive function (Morris water maze, MWM), and AD pathology (plaques formation) were assessed. A comparison was made across sexes.

RESULTS: Sex-dependent hyperactivity in AβPP/PS1 mice was …


A Comparison Of Wildfire Adaptive Traits In Juvenile Conifers Of The Northern Rockies, Andie Sonnen Jan 2022

A Comparison Of Wildfire Adaptive Traits In Juvenile Conifers Of The Northern Rockies, Andie Sonnen

Undergraduate Theses, Professional Papers, and Capstone Artifacts

Wildfire is an importance disturbance that continues to shape the ecosystems of the northern Rockies through varying patterns of frequency and intensity. Due to historical fire suppression and the hotter and drier conditions brought upon by anthropogenic climate change, wildfire frequency and intensity is increasing. These increases will alter vegetation structure and composition, but the degree to which is unknown.

Individual plant traits can offer insight into how these vegetation communities will shift, especially the particular traits that reduce fire-related mortality. To survive wildfires, juvenile northern conifers employ two strategies: increasing their bark thickness and increasing their crown height. To …


Asbury Theological Seminary Academic Catalog : 2022-2023, Asbury Theological Seminary Jan 2022

Asbury Theological Seminary Academic Catalog : 2022-2023, Asbury Theological Seminary

Academic Catalogs

No abstract provided.


Genre Fluidity In Black Speculative Fiction As An Exploration Of Blackness, Jake Upton Jan 2022

Genre Fluidity In Black Speculative Fiction As An Exploration Of Blackness, Jake Upton

English Honors Papers

No abstract provided.


Capitalocene Imaginations: Settler Colonialism, Capitalism, And The Environmental Crisis In Twenty-First-Century U.S. Literature, Zoe F. Pellegrino Jan 2022

Capitalocene Imaginations: Settler Colonialism, Capitalism, And The Environmental Crisis In Twenty-First-Century U.S. Literature, Zoe F. Pellegrino

English Honors Papers

This thesis, a study of climate fiction novels and Indigenous knowledge and poetry, argues that these texts use the power of imagination to open up alternative possibilities, otherwise foreclosed by the ideological hegemony of the capitalist climate crisis. I first explore the United States’ settler colonial history, and how the perpetuation of settler ideology over time justified the exploitative values of the capitalist system, resulting in the slow violence of our environmental crisis.

The central texts explored in this thesis are the climate fiction novels Chang-rae Lee’s On Such a Full Sea and The Ministry for the Future by Kim …


Significant Impacts Under Nepa: The Social Cost Of Greenhouse Gases As A Tool To Mitigate Climate Change, Sydney Hofferth Jan 2022

Significant Impacts Under Nepa: The Social Cost Of Greenhouse Gases As A Tool To Mitigate Climate Change, Sydney Hofferth

Michigan Journal of Environmental & Administrative Law

The increased severity of the impacts of climate change demand a re-evaluation of the legal tools that could combat it. The National Environmental Policy Act (“NEPA”) was passed to force government agencies to account for the environmental impacts of their actions. However, as it exists today, NEPA fails to require agencies to consider how their actions will mitigate or exacerbate climate change. This Note argues that agencies should be required to consider the social cost of the greenhouse gases associated with potential major actions at various stages of NEPA analysis. This change would result in increased transparency and public engagement …


Castor Oil Conversion To Biodiesel: A Process Simulation Study, Yaser M. Asal Mr, Islam M. Al-Akraa, Ahmad M. Mohammad, Razan Aymen Jan 2022

Castor Oil Conversion To Biodiesel: A Process Simulation Study, Yaser M. Asal Mr, Islam M. Al-Akraa, Ahmad M. Mohammad, Razan Aymen

Chemical Engineering

The aim of this study is to highlights the importance to shift from the use of traditional fossil fuels to biodiesel as a clean energy source. A simulation study has been conducted using ASPEN HYSIS software for the biodiesel production form castor oil. The simulation was run and the properties of the produced biodiesel were highlighted. The optimum conditions resulted in 88 % conversion.


Regional Perspectives Report Chapter 3: Ontario, Christopher J. Lemieux, Allan G. Douglas, David Pearson Jan 2022

Regional Perspectives Report Chapter 3: Ontario, Christopher J. Lemieux, Allan G. Douglas, David Pearson

Geography and Environmental Studies Faculty Publications

No abstract provided.


Structure Of A Monomeric Photosystem Ii Core Complex From A Cyanobacterium Acclimated To Far-Red Light Reveals The Functions Of Chlorophylls D And F, Christopher J. Gisriel, Gaozhong Shen, Ming-Yang Ho, Vasily Kurashov, David A. Flesher Jan 2022

Structure Of A Monomeric Photosystem Ii Core Complex From A Cyanobacterium Acclimated To Far-Red Light Reveals The Functions Of Chlorophylls D And F, Christopher J. Gisriel, Gaozhong Shen, Ming-Yang Ho, Vasily Kurashov, David A. Flesher

Faculty Publications

Far-red light (FRL) photoacclimation in cyanobacteria provides a selective growth advantage for some terrestrial cyanobacteria by expanding the range of photosynthetically active radiation to include far-red/near-infrared light (700-800 nm). During this photoacclimation process, photosystem II (PSII), the water:plastoquinone photooxidoreductase involved in oxygenic photosynthesis, is modified. The resulting FRL-PSII is comprised of FRL-specific core subunits and binds chlorophyll (Chl) d and Chl f molecules in place of several of the Chl a molecules found when cells are grown in visible light. These new Chls effectively lower the energy canonically thought to define the "red limit" for light required to drive photochemical …