Digital Commons Network^™

Constructing Neural Network Models From Brain Data Reveals Representational Transformations Linked To Adaptive Behavior, Takuya Ito, Guangyu Robert Yang, Patryk Laurent, Douglas H. Schultz, Michael W. Cole

Center for Brain, Biology, and Behavior: Faculty Publications

The human ability to adaptively implement a wide variety of tasks is thought to emerge from the dynamic transformation of cognitive information. We hypothesized that these transformations are implemented via conjunctive activations in “conjunction hubs”—brain regions that selectively integrate sensory, cognitive, and motor activations. We used recent advances in using functional connectivity to map the flow of activity between brain regions to construct a task-performing neural network model from fMRI data during a cognitive control task. We verified the importance of conjunction hubs in cognitive computations by simulating neural activity flow over this empirically-estimated functional connectivity model. These empiricallyspecified simulations …

Affective Flexibility As A Developmental Building Block Of Cognitive Reappraisal: An Fmri Study, Jordan E. Pierce, Eisha Haque, Maital Neta

Center for Brain, Biology, and Behavior: Faculty Publications

Cognitive reappraisal is a form of emotion regulation that involves reinterpreting the meaning of a stimulus, often to downregulate one’s negative affect. Reappraisal typically recruits distributed regions of prefrontal and parietal cortex to generate new appraisals and downregulate the emotional response in the amygdala. In the current study, we compared reappraisal ability in an fMRI task with affective flexibility in a sample of children and adolescents (ages 6–17, N = 76). Affective flexibility was defined as variability in valence interpretations of ambiguous (surprised) facial expressions from a second behavioral task. Results demonstrated that age and affective flexibility predicted reappraisal ability, …

Differential Impact Of Biological And Behavioral Traits On Postexercise Energy Intake In Men Andwomen, Christoph Höchsmann, Safiya E. Beckford, Jeffery A. French, Julie B. Boron, Jared Stevens, Karsten Koehler

Department of Psychology: Faculty Publications

The energy intake response to exercise is highly variable and energy (over-) compensation via increased post-exercise energy intake occurs in some individuals but not others. In explorative analyses, we aimed to identify biological and behavioral predictors of post-exercise ad libitum energy intake and whether these predictors differ from ad libitum energy intake after rest.

Conclusions:Post-exercise energy intake is associatedwithdifferent factors than energy intake after rest and behavioral and biological traits differentially affect post-exercise energy intake in men and women. In women, habitual exercise behavior seems to predict postexercise energy intake, protecting against compensatory eating. Inmen, appetite-regulating hormones play a role …

Fddm1 And Fddm2, Two Sgs3-Like Proteins, Function As A Complex To Affect Dna Methylation In Arabidopsis, Shengjun Li, Weilong Yang, Yunfeng Liu, Guangyong Li, Xiang Liu, Yaling Liu, James R. Alfano, Chi Zhang, Bin Yu

Center for Plant Science Innovation: Faculty Publications

DNA methylation is an important epigenetic modification required for the specific regulation of gene expression and the maintenance of genome stability in plants and animals. However, the mechanism of DNA demethylation remains largely unknown. Here, we show that two SGS3-like proteins, FACTOR OF DNA DEMETHYLATION 1 (FDDM1) and FDDM2, negatively affect the DNA methylation levels at ROS1-dependend DNA loci in Arabidopsis. FDDM1 binds dsRNAs with 50 overhangs through its XS (rice gene X and SGS3) domain and forms a heterodimer with FDDM2 through its XH (rice gene X Homology) domain. A lack of FDDM1 or FDDM2 increased DNA methylation levels …

Qteller: A Tool For Comparative Multi-Genomic Gene Expression Analysis, Margaret R. Woodhouse, Shatabdi Sen, David Schott, John L. Portwood Ii, Michael Freeling, Justin W. Walley, Carson M. Andorf, James Schnable

Center for Plant Science Innovation: Faculty Publications

Motivation: Over the last decade, RNA-Seq whole-genome sequencing has become a widely used method for measuring and understanding transcriptome-level changes in gene expression. Since RNA-Seq is relatively inexpensive, it can be used on multiple genomes to evaluate gene expression across many different conditions, tissues and cell types. Although many tools exist to map and compare RNA-Seq at the genomics level, few web-based tools are dedicated to making data generated for individual genomic analysis accessible and reusable at a gene-level scale for comparative analysis between genes, across different genomes and meta-analyses. Results: To address this challenge, we revamped the comparative gene …

S-Glutathionylation Of Chicken Breast Extract, Isabella Fransisco

Senior Honors Projects

The purpose of this experiment was to analyze chicken breast fractions through affinity chromatography for protein modifications by glutathione disulfide (GSSG). The fractions were incubated with different concentrations of GSSG to determine potential modified proteins. There were proteins modified with GSSG at 33 kDa in fraction I, at 16 kDa, 36 kDa, and 44kDa in fraction II, and at 36 kDa in fraction III for the concentration dependent reactions. In the time dependent reaction for fraction II, there were two major proteins at 65 kDa and 176 kDa that were modified by GSSG. Lastly, we suggest that the major modified …

What Is Transpersonal Psychology? A Concise Definition Based On 20 Years Of Research, Glenn Hartelius

International Journal of Transpersonal Studies

Research on definitions of the field of psychology and themes in the literature of the field over a period of 20 years inform this description: Transpersonal psychology is a transformative psychology of the whole person embedded within a diverse, interconnected, and evolving world that pays particular attention to states of consciousness and developmental models reflecting expansion beyond conventional notions of self. Each element of this definition is examined, as well as the four phases of definitional development within the field from its founding in 1968 up to the present.

Improved Database Filtering Technology Enables More Efficient Ab Initio Design Of Potent Peptides Against Ebola Viruses, Thomas Ripperda, Yangsheng Yu, Atul Verma, Elizabeth Klug, Michellie Thurman, St. Patrick Reid, Guangshun Wang

Journal Articles: Pathology and Microbiology

The rapid mutations of viruses such as SARS-CoV-2 require vaccine updates and the development of novel antiviral drugs. This article presents an improved database filtering technology for a more effective design of novel antiviral agents. Different from the previous approach, where the most probable parameters were obtained stepwise from the antimicrobial peptide database, we found it possible to accelerate the design process by deriving multiple parameters in a single step during the peptide amino acid analysis. The resulting peptide DFTavP1 displays the ability to inhibit Ebola virus. A deviation from the most probable peptide parameters reduces antiviral activity. The designed …

Graduate Scholar 2022: Journal Of Scholarship And Recognition, Graduate School Of Eastern Illinois University

Graduate Scholar

No abstract provided.

Stem Exploration, Caitlyn Scott, Erin Case

Honors Program: Expanded Learning Clubs

After school club for middle school students consisting of individual and partner activities that will building teamwork and problem-solving skills. The club will also introduce the students to many different areas of STEM.

Stem Club Curriculum, Emily Hogg

Honors Program: Expanded Learning Clubs

No abstract provided.

The Incoherence Challenge For Subject Combination: An Analytic Assessment, Itay Shani, Heath Williams

Philosophy Papers and Journal Articles

Panpsychism is now a bona fide potential solution to the metaphysical quandary of consciousness. Much of the debate concerning the viability of panpsychism is centered on the combination problem (CP). Intriguingly, the literature analyzing this problem displays two competing interpretations which differ in their modal force. According to the first, which we call the ‘no-necessitation view', CP consists in the absence of a priori necessitation of macro-level phenomenal facts from micro-level phenomenal facts. In contrast, the second interpretation, which we label the ‘incoherence charge’ (IC), goes further by insisting that it can be positively demonstrated that micro-experiences cannot …

Nsu Friends & Family Newsletter - November 2022, Nova Southeastern University

NSU Parent Newsletter

No abstract provided.

Electroencephalogram Classification Of Brain States Using Deep Learning Approach, Hrishitva Patel

Computer Science Faculty Scholarship

The oldest diagnostic method in the field of neurology is electroencephalography (EEG). To grasp the information contained in EEG signals, numerous deep machine learning architectures have been developed recently. In brain computer interface (BCI) systems, classification is crucial. Many recent studies have effectively employed deep learning algorithms to learn features and classify various sorts of data. A systematic review of EEG classification using deep learning was conducted in this research, resulting in 90 studies being discovered from the Web of Science and PubMed databases. Researchers looked at a variety of factors in these studies, including the task type, EEG pre-processing …

Faculty Facilitation Of Help-Seeking On Campus: A Phenomenological Study, Lillian V. Clark

Electronic Theses and Dissertations

An ever-increasing number of students on college campuses are experiencing distress, and not all students in need of care are being reached (Kitzrow, 2009, LeViness, et al., 2019). Faculty are one of the most valuable resources for identifying and connecting students to care (Kitzrow, 2009). Despite this, we know very little about the experiences of faculty working with students in distress. This study sought to understand those experiences, as well as identify the barriers to connecting students to care. A qualitative study using an Interpretive Phenomenology framework was conducted (Smith & Osborn, 2007, Moustakas, 1994). Four themes were interpreted from …

Mitigating Weight Stigma In The Medical System: Self-Compassion For Nursing Students, Ellen C. Joseph

Electronic Theses and Dissertations

Weight stigma is a form of oppression that has been shown to have a detrimental impact on the well-being of people with higher weight. Healthcare providers are one of the most common sources of weight stigma, and their stigmatizing beliefs have been found to be associated with differential care for patients with “obesity”. The current study aimed to explore the feasibility of the loving-kindness meditation (LKM) as a brief intervention that reduces weight bias in nursing students by increasing self-compassion, positive, other-focused emotions, and cognitive flexibility, in order to improve compassionate care for patients with higher weight. Participants (189 nursing …

Winter 2022 Som Alumni Connections, New York Medical College

School of Medicine

• Alums Celebrate and Reminisce at SOM Reunion
• NYMC Honors Distinguished Faculty and Alumni at Annual Founder’s Dinner
• SOM Announces New Hires
• Dr. Wang Awarded Grant to Explore New Treatment Options for Hypertension
• Drs. Medow and Stewart Awarded Grant to Study Postural Tachycardia Syndrome
• SOM Launches New Medical Education Curriculum
• NYMC At Black Men in White Coats Youth Summit
• First Epidemiological Estimates of Coma Frequency Calculated in New Study
• Disparate Access to Breast Cancer Screening and Treatment Remains for Low-Income Communities
• SOM Student Conducts Diabetes Research Through NIH-Funded Program
• NYMC Study Shows More Stroke Patients Could Benefit from Thrombectomy
• Dr. Garcia …

Inquiry: The Unversity Of Arkansas Undergraduate Research Journal - Volume 21 Issue 2 - Fall 2022, Inquiry Editors

Inquiry: The University of Arkansas Undergraduate Research Journal

No abstract provided.

Nsu Friends & Family Newsletter - September 2022, Nova Southeastern University

NSU Parent Newsletter

No abstract provided.

Ms Environmental Biology Capstone Project, Mary Strecker

Regis University Student Publications (comprehensive collection)

1. Causes of Regional Biodiversity Loss: The Case of Alpine Aquatic Macroinvertebrates

2. The Effects of Receding Glaciers on Alpine Aquatic Macroinvertebrate Diversity in Glacier National Park

3. Evaluation of Distance Sampling as a Tool for Monitoring Populations of Rare Plants (Cactaceae: Sclerocactus glaucus)

4. Protecting the Mojave Desert Tortoise and Relieving Anticipated Congestion Using an Existing Route in St. George, Utah

Reference-Free Discovery Of Nuclear Snps Permits Accurate, Sensitive Identification Of Carya (Hickory) Species And Hybrids, Robert A. Literman, Brittany M. Ott, Jun Wen, L. J. Grauke, Rachel S. Schwartz, Sara M. Handy

Biological Sciences Faculty Publications

Premise: DNA-based species identification is critical when morphological identification is restricted, but DNA-based identification pipelines typically rely on the ability to compare homologous sequence data across species. Because many clades lack robust genomic resources, we present here a bioinformatics pipeline capable of generating genome-wide single-nucleotide polymorphism (SNP) data while circumventing the need for any reference genome or annotation data. Methods: Using the SISRS bioinformatics pipeline, we generated de novo ortholog data for the genus Carya, isolating sites where genetic variation was restricted to a single Carya species (i.e., species-informative SNPs). We leveraged these SNPs to identify both full-species and hybrid …

Momentum, Rather Than Velocity, Is A More Effective Measure Of Improvements In Division Ia Football Player Performance, J. Bryan Mann, Jerry L. Mayhew, Marcel Lopes Dos Santos, J. Jay Dawes, Joseph F. Signorile

Faculty Publications - Kinesiology and Recreation

Speed, or the time to complete straight runs or agility drills, is commonly used to assess performance in collegiate American football players. However, it is common for players' speeds to plateau by the second year of eligibility, whereas their body masses continue to increase. The purpose of this study was to track change in speed, body mass, and momentum (body mass · velocity), across Division 1 football players' 4-year careers (n = 512). Complete data were derived for the 40-yd sprint (n = 82), the proagility shuttle (n = 73), and the L drill (n = 73) from the same …

Spring, Summer, Fall 2022 Graduation Survey Responses, Systems Intelligence And Data Analytics, University Of Nebraska At Omaha

Graduation

No abstract provided.

"Thank You For Your Sacrifice": Off-Label Drug Regulation Strategies After The Misuse Of Hydroxychloroquine For Covid-19, Erin Mccluan

Duquesne Law Review

In March 2020, BuzzFeed News reported that a 45-year-old patient with systemic lupus erythematosus ("SLE") was denied her long-standing hydroxychloroquine ("HCQ") prescription due to the COVID-19 pandemic.¹ Her healthcare network, Kaiser Permanente, informed her that this was necessary to "conserve[] the current supply for those who are critically ill with COVID-19."² Disturbingly, Kaiser wrote to the patient, "Thank you for the sacrifice you will be making for the sake of those that are critically ill; your sacrifice may actually save lives." ³

The patient, Dale, who asked only to be identified by her first name, told BuzzFeed News, …

Putting The "P" In Pfa: The Electronic Monitoring Of Protection From Abuse Respondents In Pennsylvania, Cameron Kehm

Duquesne Law Review

Domestic violence violently claimed Alina Sheykhet's life, despite alleged "protection" from a Protection from Abuse Order ("PFA").¹ Far from being an exception, Alina's story is yet another example among many cases that show how traditional protective order systems fail those who need protected most.² However, Alina's Law can protect PFA holders through a new remedy: the electronic monitoring of PFA respondents.³ Although Alina's Law failed to make it out of committee consideration during the 2019-2020 term,⁴ with three modifications, legislators can reintroduce Alina's Law in a passable form that would protect Pennsylvania's most vulnerable citizens.

Part …

Biometrics And An Ai Bill Of Rights, Margaret Hu

Duquesne Law Review

This Article contends that an informed discussion on an Al Bill of Rights requires grappling with biometric data collection and its integration into emerging Al systems. Biometric Al systems serve a wide range of governmental purposes, including policing, border security and immigration enforcement, and biometric cyberintelligence and biometric-enabled warfare. These systems are increasingly categorized as "high-risk" when deployed in ways that may impact fundamental constitutional rights and human rights. There is growing recognition that high-risk biometric AI systems, such as facial recognition identification, can pose unprecedented challenges to criminal procedure rights. This Article concludes that a failure to recognize these …

Making Science Communication Inclusive: An Exploratory Study Of Choices, Challenges And Change Mechanisms In The United States From An Emerging Movement, Sunshine Menezes, Kayon Murray-Johnson, Hollie Smith, Hannah Trautmann, Mehri Azizi

Natural Resources Science Faculty Publications

This qualitative study explores perspectives of U.S.A.-based science communication researchers and practitioners who attended a symposium focused on advancing inclusive science communication (ISC). ISC is a growing global movement that aims to center equity, inclusion, and marginalized perspectives in science communication. Findings underscore the complexity of systemic barriers to ISC, the critical need for resource sharing and network building, and the importance of evaluation frameworks. The authors also highlight critical dialogue as a strategic tool that might help support intentional, reciprocal, and reflexive practices in science communication.

Rethinking Habitat Occupancy Modeling And The Role Of Diel Activity In An Anthropogenic World, Kimberly Rivera, Mason Fidino, Zach J. Farris, Seth B. Magle, Asia Murphy, Brian Gerber

Natural Resources Science Faculty Publications

Current methods to model species habitat use through space and diel time are limited. Development of such models is critical when considering rapidly changing habitats where species are forced to adapt to anthropogenic change, often by shifting their diel activity across space. We use an occupancy modeling framework to specify the multistate diel occupancy model (MSDOM), which can evaluate species diel activity against continuous response variables that may impact diel activity within and across seasons or years. We used two case studies, fosas in Madagascar and coyotes in Chicago, Illinois, to conceptualize the application of this model and to quantify …

Effects Of Recreational Marijuana Use In Adolescents, Yuliya Dzholos Bjorgan, Susana Jimenez

All Electronic Theses and Dissertations

This community service project discusses short- and long-term effects of recreational marijuana use in adolescents, the most vulnerable audience to this psychoactive drug. According to the latest research, these effects include compromised physical and mental health, and diminished overall socioeconomic success and life satisfaction. Persistent marijuana use in adolescence negatively affects normal brain development, cardiovascular, immune and reproductive health. It also increases the rates of unplanned pregnancies, depression and anxiety, self-injurious behaviors, suicidal ideation and attempts. As a result of recreational marijuana intoxication, the user’s cognition, memory and perception are significantly affected, resulting in decreased IQ and employment opportunities, increased …

How Implicit Bias Contributes To Racial Disparities In Maternal Health, Michaella Saintil

Honors Undergraduate Theses

A rise in racial disparities in maternal health has become an ongoing issue in the United States. This study uses a scoping literature review method to examine the effect of implicit bias on racial disparities in maternal healthcare. Multiple articles in this study provide sufficient evidence to prove that implicit bias is a contributing factor to the alarming rise of racial disparities in maternal health outcomes. The study revealed two distinct categories that elaborate on the health crisis that has been a continuation of practices traced backed to slavery. The analysis for this research is grounded in lack of quality …