Digital Commons Network^™

The African American Nuclear Family: Investigating The Healthy Habits Of Successful Long-Term Marriages In The African American Community, Derrick L. Smith

Doctoral Dissertations and Projects

This phenomenological study sought to understand what contributed to the success of long-term marriages in the African American community. Long-term marriage was defined as those lasting 20 years or more. The family systems theory developed by Dr. Murray Bowen guided this study. The study employed a phenomenological approach to qualitative inquiry. Due to the national health crisis, all interviews were conducted through a Zoom conferencing platform. Nine married couples who have been married for at least 20 years or more participated in the study. The following criteria had to be met to participate in the study: race, length of the …

A Transcendental Phenomenological Study Of Attachment Bonding Experiences Of At-Risk Students Who Graduated High School, Nancy Marie Lawrence

Doctoral Dissertations and Projects

The purpose of this study was to describe the attachment bonding experiences of at-risk students who graduated high school. The theory guiding this study was the Attachment Theory by John Bowlby. This theory explains how attachment bonds help at-risk individuals form relationships that assist in the development of psychological health. Data collection sources were composed of participant surveys, semi-structured participant interviews, and written letters of advice to other high school at-risk students. The practical significance derived from this study demonstrated the need to train education professionals of the necessity of developing secure attachment bonds with students and to reflectively develop …

Using Intentional Relationship Building And Community Presence To Minister To An Addicted Population In Cookeville, Tennessee, James Bailey Simpson

Doctoral Dissertations and Projects

Addiction and substance abuse are banes in American society as they destroy lives, families, hopes and dreams. Individuals with potential for productive lives and societal contributions are reduced to hollow shells and find themselves laser-focused on their next fix. Cookeville, Tennessee, is no different than any other rural American town as addiction and substance abuse are prevalent, especially within the northwestern areas of the city. West View Baptist Church was planted in this area in 1950 and has actively attempted to minister to the community's residents for the last 71 years. Recently, internal issues in the congregation and increasing disconnections …

Engaging Middle School Students Through Music History Mini-Lessons: A Mixed-Methods Study, Jessica Bentley Frerich

Doctoral Dissertations and Projects

Understanding history is a vital part of learning. Nearly every question asked in a music classroom about musical context involves its history, from notation to gestures or technicality to aural listening. History can bring music to life for both the performers and listeners. Despite multiple studies on specific historical music events, music history perspectives have not been addressed in the choral classroom. Moreover, research forums have yet to explore engagement factors of middle school students through a music history curriculum in the choir classrooms. Such research could provide a valid model for educators. This mixed-methods research study seeks to determine …

Tennessee State Museum Winter 2022 Newsletter & Calendar Events, Tennessee. State Museum.

Tennessee State Museum

No abstract provided.

Sdsu Beef Day 2022 Complete Proceedings, Department Of Animal Science

SDSU Beef Day 2022 Summary Publication

This is the complete proceedings of the South Dakota State University, Department of Animal Science Beef Day 2022. The proceedings contain research presented on the following topics:
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Climate Change Awareness In The United Arab Emirates, Mariam Matar Abdulla Mohammed Almheiri

Theses

Climate change has focused public attention in the United Arab Emirates (UAE) on the role of society in environmental protection. The objective of this study was to determine the level of public awareness of climate change in the seven emirates of the UAE. The study also aimed to determine the spatial and geographical distribution and gender differences, as well as to investigate the possible influence of human activities on climate change impacts. In a cross-sectional survey, the researcher used a questionnaire to collect data from a sample of 4000 participants to answer the research questions. The drop-off pick-up (DOPU) method …

Protein Prediction For Trait Mapping In Diverse Populations, Ryan Schubert, Elyse Geoffroy, Isabelle Gregga, Ashley J. Mulford, Francois Aguet, Kristin Ardlie, Robert Gerszten, Clary Clish, David Van Den Berg, Kent D. Taylor, Peter Durda, W. Craig Johnson, Elaine Cornell, Xiuqing Guo, Yongmei Liu, Russell Tracy, Matthew Conomos, Tom Blackwell, George Papanicolaou, Tuuli Lappalainen, Anna V. Mikhaylova, Timothy A. Thornton, Michael H. Cho, Christopher R. Gignoux, Leslie Lange, Ethan Lange, Stephen S. Rich

Biology: Faculty Publications and Other Works

Genetically regulated gene expression has helped elucidate the biological mechanisms underlying complex traits. Improved high-throughput technology allows similar interrogation of the genetically regulated proteome for understanding complex trait mechanisms. Here, we used the Trans-omics for Precision Medicine (TOPMed) Multi-omics pilot study, which comprises data from Multi-Ethnic Study of Atherosclerosis (MESA), to optimize genetic predictors of the plasma proteome for genetically regulated proteome-wide association studies (PWAS) in diverse populations. We built predictive models for protein abundances using data collected in TOPMed MESA, for which we have measured 1,305 proteins by a SOMAscan assay. We compared predictive models built via elastic net …

Theoretical Explanations On The Persistence Of Ethno-Medical Pregnancy Nutrition Interventions And Recommendations For Possible Biomedical Interventions, Roselyter Riang’A

Population Health, East Africa

Background: Ethno-medical maternal health care practices during pregnancy are extensive among women especially in Low and Middle Income Countries. Little is known as to why there is an extensive use and reliance on ethno-medical malnutrition remedies over biomedical care, and that they can stand the test of time, even though some are detrimental to human health or based on scientifically incorrect notions.

Methods: From September 2014 through April 2018, a narrative review rather than a systematic review format was conducted in PubMed, Google Scholar, and Web of Science to identify and evaluate all associated literature. This review brings …

Construction And Validation Of Prognostic Nomogram For Metaplastic Breast Cancer, Yongfeng Li, Daobao Chen, Haojun Xuan, Mihnea P Dragomir, George A Calin, Xuli Meng, Meng Chen, Hongchuan Jin

Faculty, Staff and Student Publications

In this study we aimed to develop nomogram models for predicting the overall survival (OS) and cancer-specific survival (CSS) of patients with metaplastic breast cancer (MBC). Data of patients diagnosed with MBC from 1973 to 2015 were collected from the Surveillance, Epidemiology, and End Results (SEER) database. Univariate and multivariate Cox analyses were performed to identify independent prognostic factors for OS and CSS of MBC patients. The obtained prognostic variables were combined to construct nomogram models for predicting OS and CSS in patients with MBC. Model performance was evaluated using concordance index (C-index) and calibration plots. Data from 1125 patients …

Combined Il-2, Agonistic Cd3 And 4–1bb Stimulation Preserve Clonotype Hierarchy In Propagated Non-Small Cell Lung Cancer Tumor-Infiltrating Lymphocytes, Parin Shah, Marie-Andrée Forget, Meredith L Frank, Peixin Jiang, Donastas Sakellariou-Thompson, Lorenzo Federico, Roohussaba Khairullah, Chantal Alexia Neutzler, Ignacio Wistuba, Chi-Wan B Chow, Yan Long, Junya Fujimoto, Shiaw-Yih Lin, Anirban Maitra, Marcelo V Negrao, Kyle Gregory Mitchell, Annikka Weissferdt, Ara A Vaporciyan, Tina Cascone, Jack A Roth, Jianjun Zhang, Boris Sepesi, Don L Gibbons, John V Heymach, Cara L Haymaker, Daniel J Mcgrail, Alexandre Reuben, Chantale Bernatchez

Faculty, Staff and Student Publications

Background: Adoptive cell transfer (ACT) of tumor-infiltrating lymphocytes (TIL) yielded clinical benefit in patients with checkpoint blockade immunotherapy-refractory non-small cell lung cancer (NSCLC) prompting a renewed interest in TIL-ACT. This preclinical study explores the feasibility of producing a NSCLC TIL product with sufficient numbers and enhanced attributes using an improved culture method.

Methods: TIL from resected NSCLC tumors were initially cultured using (1) the traditional method using interleukin (IL)-2 alone in 24-well plates (TIL 1.0) or (2) IL-2 in combination with agonistic antibodies against CD3 and 4-1BB (Urelumab) in a G-Rex flask (TIL 3.0). TIL subsequently underwent a rapid expansion …

A Mechanistic Modeling Framework Reveals The Key Principles Underlying Tumor Metabolism, Shubham Tripathi, Jun Hyoung Park, Shivanand Pudakalakatti, Pratip K Bhattacharya, Benny Abraham Kaipparettu, Herbert Levine

Faculty, Staff and Student Publications

While aerobic glycolysis, or the Warburg effect, has for a long time been considered a hallmark of tumor metabolism, recent studies have revealed a far more complex picture. Tumor cells exhibit widespread metabolic heterogeneity, not only in their presentation of the Warburg effect but also in the nutrients and the metabolic pathways they are dependent on. Moreover, tumor cells can switch between different metabolic phenotypes in response to environmental cues and therapeutic interventions. A framework to analyze the observed metabolic heterogeneity and plasticity is, however, lacking. Using a mechanistic model that includes the key metabolic pathways active in tumor cells, …

Review Of The Invasive Forage Grass, Guinea Grass (Megathyrsus Maximus): Ecology And Potential Impacts In Arid And Semi-Arid Regions, Pushpa Soti, Vanessa Thomas

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Biology)

Several introduced African grasses are known to present recurring patterns of invasiveness and cause a severe impact on the diversity and functioning of ecosystems worldwide. Megathyrsus maximus (Guinea grass), a forage grass species native to South Africa, is reported to be highly invasive and pose a serious threat to native biodiversity in the introduced range. Despite the severe ecological threats posed by M. maximus worldwide, there is a dearth of information on the ecological and agroecological impact of M. maximus when growing in unintended areas. In this review, we present general information on M. maximus, its distribution and ecological …

Men At Peace: A Creative Ethnography, Henriette Blecher

Postgraduate

Men at Peace is a creative ethnography aiming to facilitate a functional bridge between polarising gender assumptions around communication and to communicate this bridge using poetry. Using an ethnographic approach underpinned by feminist gender theories, this project is a study of masculinities in contemporary Australian society. Stories of men’s experiences were gathered and then transformed into randomised five-lined cut up poems to reveal and understand social, emotional, spiritual, cultural, relational, and material realities of men. The stories men told during this ethnography supported the heteronormative understanding of masculinities that reinforced the narrative that “real men” should not express a wide …

There Is A Time To Be Creative: The Alignment Between Chronotype And Time Of Day, Jana Kuehnel, Ronald Bledow, Markus Kiefer

Research Collection Lee Kong Chian School Of Business

We examine the influence of chronobiological processes on creativity, specifically the influence of a person’s chronotype. Chronotype refers to the setting of a person’s biological clock that gives rise to a distinctive pattern of sleep habits and preferred diurnal activity. We propose a synchrony effect and predict that people are creative when the external clock is aligned with their internal, biological clock. According to our model, positive mood and creative self-efficacy act as affective and cognitive mechanisms of this synchrony effect. We present three studies that test our theorizing: A quasi-experimental field study with 260 employees, a day-reconstruction study with …

Applying Coleman’S Boat In Management Research: Opportunities And Challenges In Bridging Macro And Micro Theory, Amanda Cowen, Floor Rink, Ilya R. P. Cuypers, Denis Gregoire, Ingo Weller

Research Collection Lee Kong Chian School Of Business

Over the years, ongoing conversations in Academy of Management Journal—and the broader management literature—have emphasized the value of research that bridges the macro and micro domains (Hitt, Beamish, Jackson, & Mathieu, 2007; Molloy, Ployhart, & Wright, 2011; Morgeson & Hofmann, 1999; Paruchuri, Perry-Smith, Chattopadhyay, & Shaw, 2018). Calls for cross-boundary work typically argue that bridging these two domains is required to understand and solve the complex management issues that societies face (George, Howard-Grenville, Joshi, & Tihanyi, 2016; House, Rousseau, & Thomas-Hunt, 1995; Kozlowski & Klein, 2000). Responses to the organizational challenges posed by the COVID-19 pandemic, or to societal problems …

Religious Beliefs Of World Boxing Champions As A Factor Of Influence On Ukrainian Society In The Context Of Social Responsibility, Bogdan Synchak, Petro Livak, Olga Kuvaldina

Occasional Papers on Religion in Eastern Europe

The issue regarding the influence of mass media on the public consciousness is one of the priorities in the times of the digitalization of the information space. Great sports such as professional boxing are world-famous and have a wide resonance in the media. As a result, scientists are paying attention to the study of factors of influence that arise during the information coverage of sporting events. Religious beliefs are a conditional plane of differentiation of different worldview systems, but in the 21st century, they are harmoniously integrated into the colors of different cultures, nationalities, and states. Celebrities’ religious beliefs can …

Brief Of Amici Curiae Christian Medical & Dental Associations And Coptic Medical Association Of North America In Support Of Defendants' Motions To Dismiss, John A. Meiser, Francesca M. Genova, Christopher J. Schweickert

Court Briefs

No. 3:21-cv-06654-VC
Lonny Shavelson v. California Department of Health Care Services

From the Argument

Whether and to what extent doctors should be allowed to participate in intentionally ending the lives of their patients is one of the most important questions in public bioethics. The vast majority of states allow no physician participation at all. California is one of nine states that have passed laws allowing physicians to “assist” a patient’s suicide by making lethal drugs available. But each stops there. No state allows what the plaintiffs in this case now demand: that doctors be allowed to actively euthanize patients by …

Evaluation Of Amygdalin (B17) And Cucurbita Pepo (Pumpkin Seed) Activity Against Blastocystis From Diarrheic Patients In Baghdad, Iraq: In Vitro Study, Saba S. Salman, Naksheen M. Ardalan

Baghdad Science Journal

Blastocystis is a ubiquitous human and animal protozoa that inhabit the gastrointestinal tract. Metronidazole is considered the standard drug for the treatment of Blastocystis infection; however, there is growing evidence of treatment failure, hazardous side effects, and appearance of strains resistant to metronidazole. In the last era, many studies have been implicated in the quest for new treatments for Blastocystis infection, especially natural products. Attention has been focused on the effect of Amygdalin (B17) and pumpkin seed on eradicating parasitic infections. The current work was built up to explore the in vitro efficacy of two natural compounds, Amygdalin (B17) and …

Ghrelin And Leptin And Their Relations With Insulin Resistance In Diabetes Mellitus Type 2 Patients, Chinar Hameed Sadiq, Ridha Hassan Hussein, Ismail Mustafa Maulood

Baghdad Science Journal

Ghrelin and leptin are hunger hormones related to type 2 diabetes mellitus (T2DM), and the pathogenesis of T2DM is the abnormality in insulin secretion and insulin resistance (IR). The aim of this study is to evaluate ghrelin and leptin concentrations in blood and to specify the relationship of these hormones as dependent variables with some biochemical and clinical measurements in T2DM patients. In this study, forty one T2DM and forty three non-diabetes mellitus (non-DM) subjects, aged between 40-60 years and with normal weight, were enrolled. Fasting serum ghrelin and leptin were estimated by enzyme-linked immunosorbent assay (ELISA). In our results …

Effects Of The Ferrits Addition On The Properties Of Polyethylene Terephthalate, Abbas K. Saadon, Auday Hattem Shaban, Kareem A. Jasim

Baghdad Science Journal

The products of composites material are very sesetive to many variables, such as manufacturing process, additive materials, …. etc. Filler or additive plays a major role to determine the formation of the properties and behavior of the composites. In this study, polyethylene terephthalate-based compounds were produced and characterized. The work is concerned to prepare samples of Polyethylene terephthalate (PET) - zinc-ferrite (ZnFe2O4) with different addition ratio as zinc-ferrite (1, 2, 5, 10, 15 and 20) wt% obtained from mixing the solution with a hot pressing method applied under optimum conditions. The densities of the composites for all samples were calculated. …

An Epidemiological And Multidrug Resistance Study For E. Coli Isolated From Urinary Tract Infection (Three Years Of Study), Mahde S. Assafi, Fawwaz F. Ali, Reem Fouad Polis, Nisreen Jawad Sabaly, Sozan Muhsin Qarani

Baghdad Science Journal

Uropathogenic E. coli (UPEC) is problematic and still the leading cause of urinary tract infections worldwide. It is developed resistance against most antibiotics. The investigation, surveillance system, and efficient strategy will facilitate selecting an appropriate treatment that could control the bacterial distribution. The present study aims to investigate the epidemiology and associated risk factors of uropathogenic E. coli and to study their antibiotic resistance patterns. 1585 midstream urine specimens were collected from symptomatic urinary tract infections (UTI) patients (225 males and 1360 females) admitted to Zakho emergency hospital, Zakho, Kurdistan Region, Iraq from January 2016 until the end of December …

Kinetic, Isotherm, And Thermodynamic Study Of Bismarck Brown Dye Adsorption Onto Graphene Oxide And Graphene Oxide-Grafted-Poly (N-Butyl Methacrylate-Co-Methacrylic Acid), Alaa A. Mizhir, Hadi Salman Al-Lami, Ali A. Abdulwahid

Baghdad Science Journal

The adsorption behavior of Bismarck brown (BB) dye from aqueous solutions onto graphene oxide GO and graphene oxide-g-poly (n-butyl methacrylate-co-methacrylic acid) GO-g-pBCM as adsorbents was investigated. The prepared GO and GO-g-pBCM were characterized by Fourier transform infrared spectroscopy FTIR, which confirmed the compositions of the prepared adsorbents. Adsorption of BB dye onto GO and GO-g-pBCM was explored in a series of batch experiments under various conditions. The data were examined utilizing Langmuir and Freundlich isotherms. The Langmuir isotherm was seen as increasingly reasonable from the experimental information of dye on formulating adsorbents. Kinetic investigations showed that the experimental data were …

In Situ Hybridization For Molecular Detection Of Human Papilloma Viral 6 / 11 Dna In Adenoctomized Tissues From A Group Of Iraqi Pediatric Patients, Saad Hasan Mohammed Ali, Khalil Ismail A. Mohammed, Wifaq M. Ali, Suha A. Al-Fakhar, Shakir H. Mohammed Al-Alwany, Jinan M. Mousa

Baghdad Science Journal

Among more than 200 different human papilloma viral genotypes, the association of low oncogenic risk-HPV genotypes have been recognized with a variety of oral, oropharyngeal, nasopharyngeal benign tumors as well as non-neoplastic polyposis and papillomas and adenoid hypertrophy. This prospective case- control study aims to determine the rate of DNA detection of HPV genotype 6/11 in nasopharyngeal adeno- tonsillar tissues from a group of patients subjected to adenoctomy for adenoid hypertrophy . A total number of nasopharyngeal adeno-tonsillar tissue specimens from pediatric patients with adenoid hypertrophy were enrolled; 40 nasopharyngeal adeno-tonsillar tissues from patients with adenoid hypertrophy, and 20 normal …

Flow Injection Analysis With Turbidity Detection For The Quantitative Determination Of Mebeverine Hydrochloride In Pharmaceutical Formulations, Nagham S. Turkey, Jalal Nasser Jeber

Baghdad Science Journal

The main objective of this paper is to develop and validate flow injection method, a precise, accurate, simple, economic, low cost and specific turbidimetric method for the quantitative determination of mebeverine hydrochloride (MbH) in pharmaceutical preparations. A homemade NAG Dual & Solo (0-180º) analyser which contains two identical detections units (cell 1 and 2) was applied for turbidity measurements. The developed method was optimized for different chemical and physical parameters such as perception reagent concentrations, aqueous salts solutions, flow rate, the intensity of the sources light, sample volume, mixing coil and purge time. The correlation coefficients (r) of the developed …

New Tetra-Dentate Schiff Base Ligand N2o2 And Its Complexes With Some Of Metal Ions: Preparation, Identification, And Studying Their Enzymatic And Biological Activities, Khitam J. Nabhan, Amer S. Mahdi, Basim H. Al-Zaidi, Ahmad H. Ismail, Zaizafoone N. Nasif

Baghdad Science Journal

In present work, new tetra-dentate ligand, titled 3,5-bis ((E)-5-Bromo-2-hydroxy benzylidene amino) benzoic acid (H3L), was prepared via an acid-catalyzed condensation process. New four metallic ligand complexes with Co(II), Ni(II), Cu(II) and Zn(II) ions, were also prepared from the refluxing of equivalent moles. Ligand's structure and its complexes; were confirmed by numerous characterization methods, including Ultraviolet-Visible, Infrared, Mass Spectrometer, 1H and 13C Nuclear Magnetic Resonance spectra, atomic absorption, magnetic moments, and molar conductivity measurements. The results of the spectroscopic analyzes proved that the prepared ligand acts as tetradentate bi-ionic ligand and it was bonded to the metal ions by two nitrogen …

Resiliency With Forced Migrants: A Qualitative Study Of Providers And Forced Migrants Through A Resilience Perspective, Nicole Dubus

Faculty Research, Scholarly, and Creative Activity

In the last ten years, the world has experienced unprecedented, forced migration due to civil unrest, political persecution, and the ever-growing climate crisis. This is a qualitative study of the professional experiences of social workers (n = 73) working with forced migrants (n = 34) and the lived experiences of forced migrants in several countries: Germany, Greece, Iceland, Mexico, Switzerland, and the United States. Social workers reported that most of their interventions involved short-term case management that focused on securing initial housing and healthcare. Cognitive Behavioral Therapy (CBT) was the primary intervention for behavioral health issues. The recipients of these …

The Impact Of Age And Sex On Aortic Dissection Outcomes: A True Controversy Or Lack Of Standardization?, Erin F Mccaffrey, Michele Donato, Leeat Keren, Zhenghao Chen, Alea Delmastro, Megan B Fitzpatrick, Sanjana Gupta, Noah F Greenwald, Alex Baranski, William Graf, Rashmi Kumar, Marc Bosse, Christine Camacho Fullaway, Pratista K Ramdial, Erna Forgó, Vladimir Jojic, David Van Valen, Smriti Mehra, Shabaana A Khader, Sean C Bendall, Matt Van De Rijn, Daniel Kalman, Deepak Kaushal, Robert L Hunter, Niaz Banaei, Adrie J C Steyn, Purvesh Khatri, Michael Angelo

Faculty, Staff and Student Publications

Tuberculosis (TB) in humans is characterized by formation of immune-rich granulomas in infected tissues, the architecture and composition of which are thought to affect disease outcome. However, our understanding of the spatial relationships that control human granulomas is limited. Here, we used multiplexed ion beam imaging by time of flight (MIBI-TOF) to image 37 proteins in tissues from patients with active TB. We constructed a comprehensive atlas that maps 19 cell subsets across 8 spatial microenvironments. This atlas shows an IFN-γ-depleted microenvironment enriched for TGF-β, regulatory T cells and IDO1

Feral Cats In The Subtropics Of Australia—The Shamrock Station Irrigation Project, Michael Thomas Lohr, Dave Algar, Neil Hamilton, Cheryl Anne Lohr

Research outputs 2022 to 2026

Environmental damage caused by the intensification of agriculture may be compensated by implementing conservation projects directed towards reducing threatening processes and conserving threatened native species. In Australia, feral cats (Felis catus) have been a ubiquitous threatening process to Australian fauna since European colonisation. On Shamrock Station, in the north-west of Western Australia, the Argyle Cattle Company has proposed intensifying agriculture through the installation of irrigation pivots. There is concern that irrigating land and storing agricultural produce may indirectly increase the abundance of feral cats and European red foxes (Vulpes vulpes) on the property, which in turn may negatively impact threatened …

Nonignorable Missing Data, Single Index Propensity Score And Profile Synthetic Distribution Function, Xuerong Chen, Denis H. Y. Leung, Jing Qin

Research Collection School Of Economics

In missing data problems, missing not at random is difficult to handle since the response probability or propensity score is confounded with the outcome data model in the likelihood. Existing works often assume the propensity score is known up to a finite dimensional parameter. We relax this assumption and consider an unspecified single index model for the propensity score. A pseudo-likelihood based on the complete data is constructed by profiling out a synthetic distribution function that involves the unknown propensity score. The pseudo-likelihood gives asymptotically normal estimates. Simulations show the method compares favorably with existing methods.