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The Prospector, February 1, 2022, Utep Student Publications

The Prospector

Headline: UTEP Hall of Famer Jim Forbes Dies at 69

Secondary Syphilis Mimicking Marginal Zone B-Cell Lymphoma, E. Correia, Laura Gleason, Shalini Krishnasamy, Alexa Cohen, Safiyyah Bhatti, Neda Nikbakht

Department of Dermatology and Cutaneous Biology Faculty Papers

No abstract provided.

Why, How, And When Divergent Perceptions Become Dysfunctional In Organizations: A Motivated Cognition Perspective, Zhanna Lyubykh, Laurie J. Barclay, Marion Fortin, Michael R. Bashshur, Malika Khakhar

Research Collection Lee Kong Chian School Of Business

Decades of research has demonstrated that people can arrive at starkly different perceptions in the same social situations. Divergent perceptions are not inherently dysfunctional. However, if divergent perceptions are not managed effectively, they can have deleterious effects that can undermine functioning in the workplace. Drawing on a motivated cognition perspective, we outline why divergent perceptions may emerge as well as overview the benefits and drawbacks of divergent perceptions in organizational contexts. Next, we highlight the complexities associated with divergent perceptions in the workplace, including why, how, and when divergent perceptions may become dysfunctional. We also showcase theoretical insights from a …

Technical Summary, Hans Portner, Winston T. L. Chow, Et Al. See Comments For Full List Of Authors

Research Collection College of Integrative Studies

This technical summary complements and expands the key findings of the Working Group (WG) II contribution to the Sixth Assessment Report (AR6) presented in the Summary for Policymakers and covers literature accepted for publication by 1 September 2021. It provides technical understanding and is developed from the key findings of chapters and cross-chapter papers (CCPs) as presented in their executive summaries and integrates across them. The report builds on the WGII contribution to the Fifth Assessment Report (AR5) of the IPCC and three special reports of the AR6 cycle providing new knowledge and updates. The three special reports are the …

Negotiating Transportation Insecurity: Local Responses And Coping Strategies In San José, Ca, Andrew Ng, Melissa Beresford

Mineta Transportation Institute

People rely on transportation every day to access food, work, and social activities. Transportation insecurity—the lack of regular access to adequate transportation—can therefore cause significant disruptions to livelihoods. Understanding how people experience transportation insecurity in metropolitan areas may contribute to building better transportation systems and help formulate ways to alleviate persistent and underlying transportation issues. In this study, the researchers interviewed San José residents who experience transportation insecurity to better understand their experiences and identify the major ways that they cope with lack of adequate transportation. The researchers then used inductive techniques for thematic text analysis to identify patterns major …

2022 February, Morehead State University. Office Of Communications & Marketing.

Morehead State Press Release Archive, 1961 to the Present

Press releases for February of 2022.

Hippocampal Resting-State Functional Connectivity Forecasts Individual Posttraumatic Stress Disorder Symptoms: A Data-Driven Approach, Jacklynn M. Fitzgerald, Elisabeth Kate Webb, Carissa N. Weis, Ashley A. Huggins, Kenneth P. Bennett, Tara A. Miskovich, Jessica L. Krukowski, Terri A Deroon-Cassini, Christine L. Larson

Psychology Faculty Research and Publications

Background: Posttraumatic Stress Disorder (PTSD) is a debilitating disorder and there is no current accurate prediction of who develops it after trauma. Neurobiologically, individuals with chronic PTSD exhibit aberrant resting-state functional connectivity (rsFC) between the hippocampus and other brain regions (e.g., amygdala, prefrontal cortex, posterior cingulate), and these aberrations correlate with severity of illness. Prior small-scale research (n < 25) has also shown that hippocampal-rsFC measured acutely after trauma is predictive of future severity using an ROI-based approach. While a promising biomarker, to-date no study has employed a data-driven approach to test whole-brain hippocampal-FC patterns in forecasting the development of PTSD symptoms.

Methods: Ninety-eight adults at risk of PTSD were recruited from the emergency department following traumatic injury and completed resting functional magnetic resonance imaging (rsfMRI; 8min) within 1-month; 6-months later they completed the Clinician-Administered PTSD Scale (CAPS-5) for assessment of PTSD symptom …

Deprovincializing Racial Capitalism: John Crawfurd And Settler Colonialism In India, Onur Ulas Ince

Research Collection School of Social Sciences

Recent literature on racial capitalism has overwhelmingly focused on the Atlantic settler-slave formation, sidelining the history of European imperialism in Asia. This article addresses this blind spot by recovering the aborted project of British settler colonialism in India through the writings of its most prominent advocate, John Crawfurd. It is argued that Crawfurd’s vision of a liberal empire in India rejected slavery and indigenous dispossession yet remained deeply racialized in its conception of capital, labor, and value. Crawfurd elaborated a “capital theory of race,” which derived racial categories from a civilizational spectrum keyed to the capitalist organization of production. His …

Cities, Settlements And Key Infrastructure, David Dodman, Bronwyn Hayward, Mark Pelling, Vanesa Castan Broto, Winston T. L. Chow, Et Al.

Research Collection College of Integrative Studies

In all cities and urban areas, the risk faced by people and assets from hazards associated with climate change has increased (high confidence1 ). Urban areas are now home to 4.2 billion people, the majority of the world’s population. Urbanisation processes generate vulnerability and exposure which combine with climate change hazards to drive urban risk and impacts (high confidence). Globally, the most rapid growth in urban vulnerability and exposure has been in cities and settlements where adaptive capacity is limited, especially in unplanned and informal settlements in low- and middle-income nations and in smaller and medium-sized urban centres (high confidence). …

Tracking Cryptic Sars-Cov-2 Lineages Detected In Nyc Wastewater, Davida S. Smyth, Monica Trujillo, Devon A. Gregory, Marc C. Johnson, John J. Dennehy, Et Al.

Biology Faculty Publications (Archived)

Tracking SARS-CoV-2 genetic diversity is strongly indicated because diversifying selection may lead to the emergence of novel variants resistant to naturally acquired or vaccine-induced immunity. To monitor New York City (NYC) for the presence of novel variants, we deep sequence most of the receptor binding domain coding sequence of the S protein of SARS-CoV-2 isolated from the New York City wastewater. Here we report detecting increasing frequencies of novel cryptic SARS-CoV-2 lineages not recognized in GISAID’s EpiCoV database. These lineages contain mutations that had been rarely observed in clinical samples, including Q493K, Q498Y, E484A, and T572N and share many mutations …

Breast Radiation Therapy-Related Treatment Outcomes In Patients With Or Without Germline Mutations On Multigene Panel Testing, Bhavana V Chapman, Diane Liu, Yu Shen, Oluwafikayo O Olamigoke, David S Lakomy, Angelica M Gutierrez Barrera, Shane R Stecklein, Gabriel O Sawakuchi, Scott J Bright, Isabelle Bedrosian, Jennifer K Litton, Benjamin D Smith, Wendy A Woodward, George H Perkins, Karen E Hoffman, Michael C Stauder, Eric A Strom, Banu K Arun, Simona F Shaitelman

Faculty, Staff and Student Publications

PURPOSE: Multigene panel testing has increased the detection of germline mutations in patients with breast cancer. The implications of using radiation therapy (RT) to treat patients with pathogenic variant (PV) mutations are not well understood and have been studied mostly in women with only BRCA1 or BRCA2 PVs. We analyzed oncologic outcomes and toxicity after adjuvant RT in a contemporary, diverse cohort of patients with breast cancer who underwent genetic panel testing.

METHODS AND MATERIALS: We retrospectively reviewed the records of 286 women with clinical stage I-III breast cancer diagnosed from 1995 to 2017 who underwent surgery, breast or chest …

Multisite Effectiveness Study Of The Marquette Method Of Natural Family Planning Program, Qiyan Mu, Richard J. Fehring, Thomas Bouchard

College of Nursing Faculty Research and Publications

Women of reproductive age need reliable and effective family planning methods to manage their fertility. Natural family planning (NFP) methods or fertility awareness-based methods (FABMs) have been increasingly used by women due to their health benefits. Nevertheless, effectiveness of these natural methods remains inconsistent, and these methods are difficult for healthcare providers to implement in their clinical practice. The purpose of this study is to evaluate the effectiveness of the Marquette Model NFP system to avoid pregnancy for women at multiple teaching sites using twelve months of retrospectively collected teaching data. Survival analysis (Kaplan–Meier) was used to determine typical unintended …

Disinformation On Trial: Fighting Foreign Disinformation By Empowering The Victims, Ari B. Rubin

Cardozo Law Review

Foreign disinformation catapulted into the national spotlight with the 2016 presidential election, but its impact is not confined to the electoral map or season. This Article addresses the threat of foreign disinformation by proposing a new statute: a private right of action, enabling harmed persons to directly sue state or private actors, foreign or domestic, who knowingly or recklessly spread disinformation from abroad. Scholars and policymakers have proposed other, far-flung solutions ranging from greater online security to outright censorship. Each of those ideas stumbles on common challenges and lacks a valuable ingredient: an interested party, directly harmed by the foreign …

Importance Of The Intersection Of Age And Sex To Understand Variation In Incidence And Survival For Primary Malignant Gliomas, Gi-Ming Wang, Gino Cioffi, Nirav Patil, Kristin A Waite, Robert Lanese, Quinn T Ostrom, Carol Kruchko, Michael E Berens, James R Connor, Justin D Lathia, Joshua B Rubin, Jill S Barnholtz-Sloan

2020-Current year OA Pubs

BACKGROUND: Gliomas are the most common type of malignant brain and other CNS tumors, accounting for 80.8% of malignant primary brain and CNS tumors. They cause significant morbidity and mortality. This study investigates the intersection between age and sex to better understand variation of incidence and survival for glioma in the United States.

METHODS: Incidence data from 2000 to 2017 were obtained from CBTRUS, which obtains data from the NPCR and SEER, and survival data from the CDC's NPCR. Age-adjusted incidence rate ratios (IRR) per 100 000 were generated to compare male-to-female incidence by age group. Cox proportional hazard models …

Trans Doublethink And Newspeak. A Review Of Doublethink: A Feminist Challenge To Transgenderism By Janice Raymond, Heather Brunskell-Evans

Dignity: A Journal of Analysis of Exploitation and Violence

No abstract provided.

A Feminist Challenge To Transgenderism. A Review Of Doublethink: A Feminist Challenge To Transgenderism By Janice G. Raymond, Esohe Aghatise

Dignity: A Journal of Analysis of Exploitation and Violence

No abstract provided.

Improving Transcatheter Aortic Valve Interventional Predictability Via Fluid-Structure Interaction Modelling Using Patient-Specific Anatomy, Vijay Govindarajan, Arun Kolanjiyil, Nils P Johnson, Hyunggun Kim, Krishnan B Chandran, David D Mcpherson

Faculty, Staff and Student Publications

Transcatheter aortic valve replacement (TAVR) is now a standard treatment for high-surgical-risk patients with severe aortic valve stenosis. TAVR is being explored for broader indications including degenerated bioprosthetic valves, bicuspid valves and for aortic valve (AV) insufficiency. It is, however, challenging to predict whether the chosen valve size, design or its orientation would produce the most-optimal haemodynamics in the patient. Here, we present a novel patient-specific evaluation framework to realistically predict the patient's AV performance with a high-fidelity fluid-structure interaction analysis that included the patient's left ventricle and ascending aorta (AAo). We retrospectively evaluated the pre- and post-TAVR dynamics of …

Stent Retriever Versus Direct Aspiration Thrombectomy For Acute Large Vessel Occlusion: A Meta-Analysis Including 17,556 Patients, From Mr Clean To Present, Eric R. Smith, Jacob A. Bethel, Timothy B. Smith, Grant Holden, Furkan Torlak, Matthew Grimsbo, Ali Seifi, Justin R. Mascitelli

Faculty Publications

Objective

Stent retriever (SR) and direct aspiration (DA) mechanical thrombectomy (MT) improve clinical outcomes for stroke secondary to large vessel occlusion. The purpose is to perform an updated meta-analysis comparing the two techniques.

Methods

PubMed database was searched for studies between January 1, 2015, and July 5th, 2021 with mechanical thrombectomy to treat acute ischemic stroke.

Results

We identified 136 studies including 17,556 patients, with 11,258 (64.1%) patients treated by SR or a combined approach and 6298 (35.9%) patients with DA. The DA group had less posterior cerebral artery strokes, was significantly older, and had lower National Institutes …

The Bioaccumulation Testing Strategy For Nanomaterials: Correlations With Particle Properties And A Meta-Analysis Of In Vitro Fish Alternatives To In Vivo Fish Tests, R. D. Handy, N. J. Clark, D. Boyle, J. Vassallo, C. Green, F. Nasser, T. L. Botha, V. Wepener, Den Brink Nw Van, C. Svendsen

School of Biological and Marine Sciences

This meta-analysis identifies linkages between the tiers in the bioaccumulation testing strategy.

Trajectory Of Serum Bilirubin Predicts Spontaneous Recovery In A Real-World Cohort Of Patients With Alcoholic Hepatitis, Richard Parker, Joaquin Cabezas, Jose Altamirano, Juan Pablo Arab, Meritxell Ventura-Cots, Ashish Sinha, Ashwin Dhanda, Marco Arrese, C. Anne Mccune, Ian A. Rowe, Bernd Schnabl, Phillipe Mathurin, Debbie Shawcross, Juan G. Abraldes, Michael R. Lucey, Guadalupe Garcia-Tsao, Elizabeth Verna, Robert S. Brown, Francisco Bosques-Padilla, Victor Vargas, Alexandre Louvet, Andrew P. Holt, Ramon Bataller

Peninsula Medical School

No abstract provided.

Endotyping Asthma - Profiling The Metabolic Dimension?, Michael J. Wilde, Salman Siddiqui

School of Geography, Earth and Environmental Sciences

Asthma has long been recognised as a heterogeneous disease, and the notion of discrete endotypes of asthma has been prevalent for over a decade [1]. However, despite the success in identifying and targeting type-2 inflammation in asthma, the identification of tractable endotypes - has remained elusive; with not a single endotype defined with certainty. Here, Kelly et al, have reported putative novel asthma endotypes, defined using metabolomics (metabo-endotypes), in childhood asthma [2]. The metabolomics included unbiased multi-platform, metabolic profiling, using liquid chromatography and tandem mass spectrometry (LC-MS). The metabolic endotypes generated, were replicated against clinical outcomes in an independent cohort, …

Extracellular Secretion Of A Cutinase With Polyester-Degrading Potential By E. Coli Using A Novel Signal Peptide From Amycolatopsis Mediterranei, Yeqi Tan, Gemma K. Kinsella, Gary T. Henehan, Barry J. Ryan

Articles

Recent studies in this laboratory showed that an extracellular cutinase from A. mediterranei (AmCut) was able to degrade the plastics polycaprolactone and polybutylene succinate. Such plastics can be slow to degrade in soils due to a lack of efficient polyester degrading organisms. AmCut also showed potential for the biocatalytic synthesis of esters by reverse hydrolysis.

The gene for AmCut has an upstream leader sequence whose transcript is not present in the purified enzyme. In this study, we show using predictive modelling, that this sequence codes for an N-terminal signal peptide that directs transmembrane expression via the Sec secretion pathway.

E. …

The Utilization Of Algae And Seaweed Biomass For Bioremediation Of Heavy Metal-Contaminated Wastewater, Hussein Znad, Md Rabiul Awual, Sri Martini

Research outputs 2022 to 2026

The presence of heavy metals in water bodies is linked to the increasing number of industries and populations. This has serious consequences for the quality of human health and the environment. In accordance with this issue, water and wastewater treatment technologies including ion exchange, chemical extraction, and hydrolysis should be conducted as a first water purification stage. However, the sequestration of these toxic substances tends to be expensive, especially for large scale treatment methods that require tedious control and have limited efficiency. Therefore, adsorption methods using adsorbents derived from biomass represent a promising alternative due to their great efficiency and …

Learning Fruit Class From Short Wave Near Infrared Spectral Features, An Ai Approach Towards Determining Fruit Type, Ayesha Zeb, Waqar Shahid Qureshi, Abdul Ghafoor, Dympna O'Sullivan

Conference papers

This paper analyzes the potential of using shortwave NIRS (near-infrared spectroscopy) for fruit classification problems. The research focuses on O-H and C-H overtone features of fruit and its correlation with NIRS and therefore opens a new dimension of fruit classification problems using NIRS. Eleven fruits, which include apple, cherry, hass, kiwi, grapes, mango, melon, orange, loquat, plum, and apricot, were used in this study to cover physical characteristics such as peel thinness, pulp, seed thickness, and size. NIR spectral data is collected using the industry-standard F-750 fruit quality meter (wavelength range 300-1100nm) for all fruit mentioned above. Different shallow machine …

Study Of Synaptic Properties Of Honey Thin Film For Neuromorphic Systems, Brandon Sueoka, Kuan Yew Cheong, Feng Zhao

Electrical and Computer Engineering Faculty Research & Creative Works

Besides conventional electrical properties, materials for emerging artificial synaptic devices in brain-inspired neuromorphic systems need to have properties analogous to those of biological synapses, such as synaptic plasticity. In this work, we investigated, for the first time, the synaptic properties of a natural bio-organic material – honey. The honey film was sandwiched between Ag and ITO to form a structure resembling biological synapse. Neural facilitation, an essential synaptic plasticity, was demonstrated by honey thin film with a larger facilitation index, wider interval time range and higher dynamic filtering gain than other natural bio-organic materials. The results indicate that honey is …

Resource Availability And Implications For The Development Of Plug‐In Electric Vehicles, Ona Egbue, Suzanna Long, Seong Dae Kim

Engineering Management and Systems Engineering Faculty Research & Creative Works

Plug‐in electric vehicles (PEVs) have immense potential for reducing greenhouse gas emissions and dependence on fossil fuels, and for smart grid applications. Although a great deal of research is focused on technological limitations that affect PEV battery performance targets, a major and arguably equal concern is the constraint imposed by the finite availability of elements or resources used in the manufacture of PEV batteries. Availability of resources, such as lithium, for batteries is critical to the future of PEVs and is, therefore, a topic that needs attention. This study addresses the issues related to lithium availability and sustainability, particularly supply …

Concentration Polarization Controlin Stand-Alone And Hybrid Forward Osmosis Systems: Recent Technological Advancements And Future Directions, W. Suwaileh, Masoumeh Zargar, A. Abdala, F. A. Siddiqui, Mehdi Khiadani, A. Abdel-Wahab

Research outputs 2022 to 2026

Forward osmosis (FO) has received significant attention recently. FO has high potentials for integration with other water treatment technologies. However, concentration polarization (CP) remains a significant challenge in FO membrane applications. In particular, internal CP (ICP) reduces the permeability of FO membranes by nearly 80%. The development of FO processes and their applications can greatly benefit from strategies that detect and control CP in standalone and integrated FO systems. This requires consideration of FO membrane structures, materials, configurations, operating conditions, and modification and cleaning strategies. This review provides a state-of-the-art analysis of recent literature on CP detection and control with …

Is Tissue Still The Issue? The Promise Of Liquid Biopsy In Uveal Melanoma, Daniël P. De Bruyn, Aaron B. Beasley, Robert M. Verdijk, Natasha M. Van Poppelen, Dion Paridaens, Ronald O.B. De Keizer, Nicole C. Naus, Elin S. Gray, Annelies De Klein, Erwin Brosens, Emine Kiliç

Research outputs 2022 to 2026

Uveal melanoma (UM) is the second most frequent type of melanoma. Therapeutic options for UM favor minimally invasive techniques such as irradiation for vision preservation. As a consequence, no tumor material is obtained. Without available tissue, molecular analyses for gene expression, mutation or copy number analysis cannot be performed. Thus, proper patient stratification is impossible and patients' uncertainty about their prognosis rises. Minimally invasive techniques have been studied for prognostication in UM. Blood-based biomarker analysis has become more common in recent years; however, no clinically standardized protocol exists. This review summarizes insights in biomarker analysis, addressing new insights in circulating …

Phosphorylation Of The Aggregate-Forming Protein Alpha-Synuclein On Serine-129 Inhibits Its Dna-Bending Properties, Sydney E. Dent, Dennisha P. King, Valerie R. Osterberg, Eleanor K. Adams, Marilyn R. Mackiewicz, Tamily A. Weissman, Vivek K. Unni

Chemistry Faculty Publications and Presentations

Alpha-synuclein (aSyn) is a vertebrate protein, normally found within the presynaptic nerve terminal and nucleus, which is known to form somatic and neuritic aggregates in certain neurodegenerative diseases. Disease-associated aggregates of aSyn are heavily phosphorylated at serine-129 (pSyn), while normal aSyn protein is not. Within the nucleus, aSyn can directly bind DNA, but the mechanism of binding and the potential modulatory roles of phosphorylation are poorly understood. Here we demonstrate using a combination of electrophoretic mobility shift assay and atomic force microscopy approaches that both aSyn and pSyn can bind DNA within the major groove, in a DNA length-dependent manner …

Dissecting The Shared Genetic Architecture Of Suicide Attempt, Psychiatric Disorders, And Known Risk Factors, Niamh Mullins, Joo Eun Kang, Adrian I. Campos, Jonathan R.I. Coleman, Ney Alliey Rodriguez

School of Medicine Publications

Background: Suicide is a leading cause of death worldwide, and nonfatal suicide attempts, which occur far more frequently, are a major source of disability and social and economic burden. Both have substantial genetic etiology, which is partially shared and partially distinct from that of related psychiatric disorders. Methods: We conducted a genome-wide association study (GWAS) of 29,782 suicide attempt (SA) cases and 519,961 controls in the International Suicide Genetics Consortium (ISGC). The GWAS of SA was conditioned on psychiatric disorders using GWAS summary statistics via multitrait-based conditional and joint analysis, to remove genetic effects on SA mediated by psychiatric disorders. …