Digital Commons Network^™

Pulling The Trigger On Hunting Regulations For Lead Ammunition, Lydia Shields

Villanova Environmental Law Journal (1991 - )

No abstract provided.

Rethinking Public Health Risk Mitigation Strategies: Recognizing The Biosocial Nature Of Covid-19, Grace Savard

CSB and SJU Distinguished Thesis

The SARS-CoV-2 virus has rippled throughout every aspect of society and influenced how we live, breathe, and interact with one another. The purpose of this thesis is to explore the interdisciplinary biosocial impacts of the SARS-CoV-2 virus and the resulting disease, COVID-19. In order to understand the complexities of caregiving during COVID-19, we conducted 75 semi-structured interviews with 55 healthcare providers across 18 states over a span of two years. This research assesses how COVID-19 risk mitigation strategies were designed with the primary intention to stop the spread of the virus rather than account for the longer-term social and biological …

Coeliac Plexus Radiosurgery For Pain Management In Patients With Advanced Cancer : Study Protocol For A Phase Ii Clinical Trial, Galia Jacobson, Ronen Fluss, Amira Dany-Benshushan, Talia Golan, Tikva Meron, Camilla Zimmermann, Laura A Dawson, Aisling Barry, Marcin Miszczyk, Michael Buckstein, Dayssy Diaz Pardo, Artur Aguiar, Liat Hammer, Adam Dicker, Maoz Ben-Ailan, Ofir Morag, David Hausner, Zvi Symon, Yaacov R Lawrence

Department of Radiation Oncology Faculty Papers

Introduction: Pancreatic cancer is characterised by severe mid-back and epigastric pain caused by tumour invasion of the coeliac nerve plexus. This pain is often poorly managed with standard treatments. This clinical trial investigates a novel approach in which high-dose radiation (radiosurgery) is targeted to the retroperitoneal coeliac plexus nerve bundle. Preliminary results from a single institution pilot trial are promising: pain relief is substantial and side effects minimal. The goals of this study are to validate these findings in an international multisetting, and investigate the impact on quality of life and functional status among patients with terminal cancer.

Methods and …

Transformation Of Lipid Vesicles Into Micelles By Adding Nonionic Surfactants: Elucidating The Structural Pathway And The Intermediate Structures, Igor Kevin Mkam Tsengam, Marzhana Omarova, Elizabeth G. Kelley, Alon Mccormick, Geoffrey D. Bothun, Srinivasa R. Raghavan, Vijay T. John

Chemical, Biomolecular, and Materials Engineering Faculty Publications

The phospholipid lecithin (L) and the nonionic surfactant Tween 80 (T) are used together in various contexts, including in drug delivery and oil spill remediation. There is hence a need to elucidate the nanostructures in LT mixtures, which is the focus of this paper. We study these mixtures using cryogenic transmission electron microscopy (cryo-TEM), coupled with dynamic light scattering and small-angle neutron scattering. As the concentration of Tween 80 is increased, the vesicles formed by lecithin are transformed into spherical micelles. We identify bicelles (i.e., disc-like micelles) as well as cylindrical micelles as the key stable nanostructures formed at intermediate …

Micrornas In Pulmonary Hypertension, From Pathogenesis To Diagnosis And Treatment, Junhua Xu, John Linneman, Yanfeng Zhong, Haoyang Yin, Qinyi Xia, Kang Kang, Deming Gou

Open Access Publications

Pulmonary hypertension (PH) is a fatal and untreatable disease, ultimately leading to right heart failure and eventually death. microRNAs are small, non-coding endogenous RNA molecules that can regulate gene expression and influence various biological processes. Changes in microRNA expression levels contribute to various cardiovascular disorders, and microRNAs have been shown to play a critical role in PH pathogenesis. In recent years, numerous studies have explored the role of microRNAs in PH, focusing on the expression profiles of microRNAs and their signaling pathways in pulmonary artery smooth muscle cells (PASMCs) or pulmonary artery endothelial cells (PAECs), PH models, and PH patients. …

Mirrors To The Soul: Elementary Preservice Teachers’ Critical Reflections Of Situating Race, Racism, And Antiracism Within The Literacy Curriculum, Marian Cunningham

Theses and Dissertations

Research that engages preservice teachers in critical reflective practices may reveal the level at which they understand and confront their own biases when addressing race within the institutions and societies they interact. This study was conducted to understand the depth in which elementary preservice teachers critically reflect on their own racialized experiences and beliefs and how they situate race within the literacy curriculum through the lens of critical race theory. Semi-structured interviews were conducted with 21 preservice teachers. Findings indicated that preservice teachers believe antiracist themes should be integrated into literacy. However, due to lack of exposure, limited coursework, and …

Whalesong 2022-03-24 (V.42 No.2), Mike Flunker, Kenedy Williams, Lucas Stewart, Sierra Lissick, Jon Calleja, Becky Iverson, Adam Zenger

Whalesong

No abstract provided.

Fault Lines In The Application Of International Humanitarian Law To Cyberwarfare, Humna Sohail

Journal of Digital Forensics, Security and Law

The dynamics of warfare have changed from the conventional wars fought on the battlefield to virtual warfare as states have been involved in the cyber arms race. From simple distributed denial-of-service (DDoS) attacks to the potent Stuxnet and Flame the cyber weapons vary in their potential human cost. The Law of Armed Conflict (LOAC) is drafted flexibly to adapt to changing circumstances. This paper is primarily based upon the assumption that existing treaty law is sufficient in many aspects yet in some areas treaty-making is also needed. What is the foreseeable solution is the comprehensive state practice for interpreting the …

Herstory: Women And Drugs. Women In The Environment Perspective Using Meta-Ethnography, Tammy Ann Shay

Social Work Doctoral Dissertations

Women are underrepresented in drug and alcohol treatment programs globally. Socio-economic inequities and stigma continue to plague women seeking treatment. The macro and mezzo environments are often ignored, with more of a focus on women "choosing" drugs over traditional feminine roles. Social consequences and punishment are used to deter rather than to treat. Meta-ethnography is a seven-phase qualitative evidence synthesis valuable method for social research. Meta-ethnography was used to explore the treatment barriers involved with women seeking drug treatment. Qualitative studies were examined from EBSCO, PubMed, ProQuest, JSTOR, PubPsych, ResearchGate, ScienceDirect, Google Scholar, and Sage, yielding 422 peer-reviewed records. Inclusion …

Excessive Sanctions & Evolving Standards Of Decency: The Mitigating Nature Of Sexual Trauma For Juvenile Survivors Who Murder, Ingrid Hofeldt

Minnesota Journal of Law, Science & Technology

No abstract provided.

Activated Carbon As Superadsorbent And Sustainable Material For Diverse Applications, Gaurav Sharma, Shweta Sharma, Amit Kumar, Chin Wei Lai, Mu. Naushad, Shehnaz (Panjab University Shehnaz (Panjab University, Jibran Iqbal, Florian J. Stadler

All Works

Activated carbon is a carbonaceous material with highly porous structure. Different functionalities can be introduced to its surface by various physical and chemical treatments. Various precursors can be used for the synthesis of activated carbon such as fossil fuels, agricultural wastes, and lignocellulosic wastes, etc. Number of papers have been reported in literature devoted to the synthesis, characterization, and various applications of activated carbon. Herein, in this review, special attention has been paid to the basic properties of activated carbon and its surface chemistry originated due to physical and chemical treatment. In addition, a general introduction to adsorption process, various …

Tijuana River Valley Pollution: How The Environmental Protection Agency Expects To End A Ninety-Year Environmental And Public Health Crisis, Andrew Simmons

Villanova Environmental Law Journal (1991 - )

No abstract provided.

Using Quantitative Imaging For Personalized Medicine In Pancreatic Cancer: A Review Of Radiomics And Deep Learning Applications, Kiersten Preuss, Nate Thach, Xiaoying Liang, Michael Baine, Justin Chen, Chi Zhang, Huijing Du, Hongfeng Yu, Chi Lin, Michael A. Hollingsworth, Dandan Zheng

School of Biological Sciences: Faculty Publications

As the most lethal major cancer, pancreatic cancer is a global healthcare challenge. Personalized medicine utilizing cutting-edge multi-omics data holds potential for major breakthroughs in tackling this critical problem. Radiomics and deep learning, two trendy quantitative imaging methods that take advantage of data science and modern medical imaging, have shown increasing promise in advancing the precision management of pancreatic cancer via diagnosing of precursor diseases, early detection, accurate diagnosis, and treatment personalization and optimization. Radiomics employs manually-crafted features, while deep learning applies computer-generated automatic features. These two methods aim to mine hidden information in medical images that is missed by …

Modelling Physico-Chemical Properties Of Binary Nano-Alloys By Nano-Thermodynamics And Machine Learning, Luke David Geoffrion

Theses and Dissertations

Nanoscience and nanotechnology are some of the fastest growing fields of materials science that have given impact to several fields of science including biology, medicine, and catalysis. These applications take advantage of several properties of nanoscale materials that are present at sizes below 100 nm namely the increased surface to volume ratio. From a theoretical point of view, nanoscience research is dominated by Density Functional Theory and Molecular Dynamics. These techniques dominate for good reason, but are not without their own limitations due to their computational complexity which results in very long calculation time to complete on materials whose size …

The Effects Of Victimization And Trauma On Well-Being, Physical Health Nutritional Habits, And Resting Heart Rate (Rhr) Based On Gender And Sexual Orientation, Mary Hannah Hughes

Theses and Dissertations

There is a well-established and growing body of research dedicated to understanding the influence of past victimization on physical health outcomes. Consequently, knowledge on identifying how past victimization types influence each domain of physical health and if these outcomes differ by gender and sexual orientation remains largely absent within literature. Therefore, the purpose of the following study is to expound upon victimization literature by examining the physical health outcomes associated with different victimization types and to examine how these factors differ by both gender and sexual orientation with regard to victimization type (personal, property, and stalking). Guided by both life-course …

Recommendations For Discipline-Specific Fairness Evaluation Derived From Applying An Ensemble Of Evaluation Tools, Karsten Peters-Von Gehlen, Heinke Höck, Andrej Fast, Daniel Heydebreck, Andrea Lammert, Hannes Thiemann

Copyright, Fair Use, Scholarly Communication, etc.

From a research data repositories’ perspective, offering research data management services in line with the FAIR principles is becoming increasingly important. However, there exists no globally established and trusted approach to evaluate FAIRness to date. Here, we apply five different available FAIRness evaluation approaches to selected data archived in the World Data Center for Climate (WDCC). Two approaches are purely automatic, two approaches are purely manual and one approach applies a hybrid method (manual and automatic combined).

The results of our evaluation show an overall mean FAIR score of WDCC-archived (meta) data of 0.67 of 1, with a range of …

Blinatumomab Maintenance After Allogeneic Hematopoietic Cell Transplantation For B-Lineage Acute Lymphoblastic Leukemia, Mahmoud R Gaballa, Pinaki Banerjee, Denái R Milton, Xianli Jiang, Christina Ganesh, Sajad Khazal, Vandana Nandivada, Sanjida Islam, Mecit Kaplan, May Daher, Rafet Basar, Amin Alousi, Rohtesh Mehta, Gheath Alatrash, Issa Khouri, Betul Oran, David Marin, Uday Popat, Amanda Olson, Priti Tewari, Nitin Jain, Elias Jabbour, Farhad Ravandi, Hagop Kantarjian, Ken Chen, Richard Champlin, Elizabeth Shpall, Katayoun Rezvani, Partow Kebriaei

Faculty, Staff and Student Publications

Patients with B-lineage acute lymphoblastic leukemia (ALL) are at high-risk for relapse after allogeneic hematopoietic cell transplantation (HCT). We conducted a single-center phase 2 study evaluating the feasibility of 4 cycles of blinatumomab administered every 3 months during the first year after HCT in an effort to mitigate relapse in high-risk ALL patients. Twenty-one of 23 enrolled patients received at least 1 cycle of blinatumomab and were included in the analysis. The median time from HCT to the first cycle of blinatumomab was 78 days (range, 44 to 105). Twelve patients (57%) completed all 4 treatment cycles. Neutropenia was the …

Bombycid Species, Trilocha Varians (Lepidoptera: Bombycidae) An Emerging Insect Pest Of Ornamental Plants In Pakistan, Muhammad Mansoor, Waheed Ahmad, Roshan Zada, Hafiz Muhammad Faisal Ayub, Imtiaz Khan, Musaddiq Israr, Awais Rasool, Muhammad Shehzad Khan

Journal of Bioresource Management

Weeping fig, Ficus benjamina, belongs to Moraceae family is planted alongside the roads as decorative plant and landscape purposes. Fig plants were seen infested with Trilocha varians for three years ago in University of Agriculture Faisalabad, Punjab Pakistan. The complete defoliation, even death of whole plant was observed caused by larvae. The complete metamorphosis was recorded with five larval instars. The fecundity of female was recorded very high (180-300) during its whole life period. The results showed that male was long lived than female. Further studies on current pest biology, host range, biological fauna and management associated with it are …

Estimation Of Chromium In Soil-Plant-Animal Continuum: A Case Study In Ruminants Of Punjab, Pakistan, Kafeel Ahmad, Zafar Iqbal Khan, Saman Nazar, Ifra Saleem Malik, Asma Ashfaq, Mudasra Munir, Humayun Bashir, Fatima Ghulam Muhammad, Shahzad Akhtar, Muhammad Nadeem, Shahid Mehmoud, Muhammad Umer Farooq Awan, Mumtaz Akhtar, Shahzadi Mahpara

Journal of Bioresource Management

The increased use of waste water for agriculture purposes has increased around the globe. There are toxic metals present in waste water which affect plants, animals and human health. But at the same time it also contains useful nutrients which increase growth of plants. Different indices were applied to evaluate the metals present in water soil plant and milk. Various and correlation were determined with the help of SPSS, mean significance was found at the probability levels of 0.05, 0.001 and 0.01. The highest value of Cr was found in Avena sativa (0.7872 mg/kg) collected from site 5 while lower …

Amelioration Of Cr (Vi) Into Cr (Iii) By Some Heavy Metal Resistant Bacterial Strains Isolated From Naran Valley, Ifrah Fayyaz, Asma Kalsoom, Rida Batool

Journal of Bioresource Management

Total thirty-two strains were isolated from both water and soil samples collected from Naran Valley which is surrounded by the rugged mountains, located in the province of Khyber Pakhtunkhwa, Pakistan. Streak plate method was used to screen the bacterial strains for resistance against selected heavy metals like chromium (Cr), cobalt (Co), copper (Cu), nickel (Ni) and zinc (Zn). Resistance against multiple heavy metals was shown by all the strains, but S15 and W15 were significant as they exhibited a maximum resistance to chromium and copper (1200 µg/ml). These strains also presented multiple antibiotic (ampicillin, tetracycline, chloramphenicol, and erythromycin) resistance patterns. …

Microbiological Contamination Associated With The Proximity Of A Refuse Dumpsite To A River Situated In Okada, Edo State, Nigeria, Ebere J. Okafor-Elenwo, Odaro S. Imade, Osazee E. Izevbuwa

Journal of Bioresource Management

This study was performed to evaluate the potential contamination of the Okponha river situated near a dumpsite in Okada, Edo State, Nigeria. Water samples were collected and analyzed for bacteriological and parasitological quality using standard procedures. Isolation and enumeration of bacterial colonies were performed by pour plate technique and the isolated bacteria were identified by standard phenotypic tests. Helminths and protozoa were screened by the direct smear technique. The values of HPC (3.79 ± 0.12 log₁₀ CFU/ml) and TCC (2.20 ± 0.14 log₁₀ CFU/ml) obtained from the river water samples exceeded WHO and NAFDAC recommended limits (≤ 2 …

Checklist Of Zooplankton Of The Halda River, Chattogram, Bangladesh, Md. Safiqul Islam, M.A. Azadi, Munira Nasiruddin, Md. Tajul Islam

Journal of Bioresource Management

The River Halda is one of the important natural breeding grounds of Indian major carp (Labeo rohita, Labeo calbasu, Gibelion catla, Cirrhinus mrigala) in Bangladesh for its unique physicochemical and biological properties of water. The productivity of the Halda ecosystem mainly depends on the plankton diversity. Zooplankton directly affects the productivity of the Halda River ecosystem. Research work was conducted for the two years extending from January 2017 to December 2018 to identify the zooplankton community of the Halda River. A total of 71 species of zooplankton under 37 genera belonging to 9 groups were identified. The dominant …

Current Epidemiological Status And Antibiotic Resistance Profile Of Urinary Tract Infection, Muddasir Khan, Syed Hussain Shah, M. Abdullah, Muhammad Salman, Fawad Hayat, Raheela Sarwar, Neelma Hassan, Sohail Ahmad Jan, M. Saddam, Ziaur Rahman, Imran Qazi

Journal of Bioresource Management

With a longitudinal (2020–2021) completion, a set of 300 urine samples of individuals suspected of UTI was characterized based on the biochemical analysis and Kirby Bauer's disc diffusion method. Throughout, a total of 167 samples revealed UTI positivity by obtaining bacterial growth. Reporting that E. coli (69.4 %) was the most dominant when compared with Klebsiella (14.3 %), Proteus (5.9 %), S. aureus (4.7 %), P. aeruginosa (3.5 %), and Enterobacter (1.7 %), respectively. Gender-wise discrimination showed that E. coli was highly distributed among female (50.2 %) patients. A prominent percentage of E. coli (41.9 %) was found in the …

In-Silico Determination Of Phytochemicals Against Spike Protein Of Covid-19, Muhammad Irfan, Muhammad Adil, Areej Fatima, Arooj Fatima, Ammara Khalid, Muhammad Bilal

Journal of Bioresource Management

Spike protein is present on the exterior of SARS-CoV-2 that mediates the binding of virus with human ACE2 receptor. S-protein has the ability to mutate in a short span of time. Using S-protein as a therapeutic target, Covid-19 infection can be prevented. Many plant-derived phytochemicals are found effective to treat viral infections. In this study, we selected top 10 phytochemicals following the Lipinski’s rule of five from total 82 candidate phytochemicals. The binding energies were determined through molecular docking of the phytochemical ligands. Top three compounds having maximal interactions and lowest binding energies were visualized. We suggested Dictamnine, Deoxypodophyllotoxin and …

Application Of Vibration Technique For The Control Of Physical Properties Of Yam (Dioscorea Spp.) Sprouts During Storage In Funaab, Nigeria Environment, Kifilideen Lekan Osanyinpeju, Adewole A. Aderinlewo, Olawale U. Dairo, Olayide R. Adetunji, Emmanuel S.A. Ajisegiri

Journal of Bioresource Management

Early sprouting of yam tuber is a typical problem during storage resulting into weight losses, deterioration, shrinkage and reduction in quality. This research work therefore carried out investigation on the application of vibration technique for the control of physical properties of yam (Dioscorea spp.) sprouts during storage in FUNAAB, Nigeria environment. The physical properties (length, number and weight of sprout, number of leaves and weight of roots) of the yam sprouts were determined for 140 white yam tubers. The yam tubers were divided into 108 experiment and 32 as control. The factors of the experimental design examined were frequency, …

Environmental And Habitat Preferences Of The Algerian Hedgehog Atelerix Algirus(Lereboullet, 1842) In El Kala National Park (North-East Algeria), Sakraoui Rym, Boukheroufa Mehdi, Dadci Walid, Abdallah Khadidjawissal, Senaoui Charafeddine, Sakraoui Feriel, Benyacoub Slim

Journal of Bioresource Management

We conducted this study to identify the preferred habitat of Atelerix algirus in the National Park of El Kala (PNEK), through the analysis of the catches rates of the species combined to an ethno zoological survey carried out among the residents. The study was conducted between January 2010 and December 2011, in five localities of the Park, different by their useful areas (forests and agricultural land) and their degree of urbanization: Raml Souk, El Aioun, Berrihane, El Kala and Bougous. We also surveyed 57 residents of Berrihane locality. Our results identified the locality of Berrihane as the preferred area of …

A Review On Empirical Approach To Therapeutic Recombinant Protein Production Factories: Applications, Pharmacokinetics And Challenges, Zahra Naz, Ambreen Kanwal, Asima Tayyeb

Journal of Bioresource Management

Major portion of the proteins in a cell refers to their critical roles in metabolism of the living body. Proteins dysfunction results in the severe disorders which need to be treated in time. For this, respective proteins can be extracted by the external sources and be supplied to the human beings. Such medicinal proteins are known as therapeutic proteins (TPs). This review summarizes some of the key areas about these miracle proteins like their types, classification, production factories, routes of administration, pharmacokinetics, and potential applications. Furthermore, challenges and hurdles faced in getting a potential protein drug, its FDA approval and …

Do 2h And 18o In Leaf Water Reflect Environmental Drivers Differently?, Lucas A. Cernusak, Adrià Barbeta, Rosemary T. Bush, Rebekka Eichstaedt Bögelein, Juan Pedro Ferrio, Lawrence B. Flanagan, Arthur Gessler, Paula Martín-Gómez, Regina T. Hirl, Ansgar Kahmen, Claudia Keitel, Chun-Ta Lai, Niels C. Munksgaard, Daniel B. Nelson, Jérôme Ogée, John S. Roden, Hans Schnyder, Steve L. Voelker, Lixin Wang, Hilary Stuart-Williams, Lisa Wingate, Wusheng Yu, Liangju Zhao, Matthias Cuntz

Michigan Tech Publications, Part 1

We compiled hydrogen and oxygen stable isotope compositions (δ H and δ O) of leaf water from multiple biomes to examine variations with environmental drivers. Leaf water δ H was more closely correlated with δ H of xylem water or atmospheric vapour, whereas leaf water δ O was more closely correlated with air relative humidity. This resulted from the larger proportional range for δ H of meteoric waters relative to the extent of leaf water evaporative enrichment compared with δ O. We next expressed leaf water as isotopic enrichment above xylem water (Δ H and Δ O) to remove the …

Stepping-Stones And Mediators Of Pandemic Expansion: A Context For Humans As Ecological Super-Spreaders, Eric P. Hoberg, Walter A. Boeger, Daniel R. Brooks, Valeria Trivellone, Salvatore J. Agosta

MANTER: Journal of Parasite Biodiversity

Humans represent ecological super-spreaders in the dissemination and introduction of pathogens. These processes, consistent with the dynamics of the Stockholm paradigm, are exemplified in the origin and globalized distributions of SARS-CoV-2 since initial recognition in central Asia during 2019 and 2020. SARS-like viruses are not widespread in mammals but appear widespread in chiropterans. Bats are isolated ecologically from most other assemblages of mammals in terrestrial systems. Humans may be the stepping-stone hosts for broad global dissemination and wider infection (given the opportunity) among diverse assemblages of mammals in which host and viral capacity are compatible. Human globalization mediated insertion in …

Southeast Asia Must Narrow Down The Yield Gap To Continue To Be A Major Rice Bowl, Shen Yuan, Alexander M. Stuart, Alice G. Laborte, Juan I. Rattalino Edreira, Achim Dobermann, Le Vu Ngoc Kien, Lưu Thị Thúy, Kritkamol Paothong, Prachya Traesang, Khin Myo Tint, Su Su San, Marcelino Q. Villafuerte Ii, Emma D. Quicho, Anny Ruth P. Pame, Rathmuny Then, Rica Joy Flor, Neak Thon, Fahmuddin Agus, Nurwulan Agustiani, Nanyan Deng, Tao Li, Patricio Grassini

Department of Agronomy and Horticulture: Faculty Publications

Southeast Asia is a major rice-producing region with a high level of internal consumption and accounting for 40% of global rice exports. Limited land resources, climate change and yield stagnation during recent years have once again raised concerns about the capacity of the region to remain as a large net exporter. Here we use a modelling approach to map rice yield gaps and assess production potential and net exports by 2040. We find that the average yield gap represents 48% of the yield potential estimate for the region, but there are substantial differences among countries. Exploitable yield gaps are relatively …