Digital Commons Network^™

Japan’S Covid 19 Infection Rate: A Focus On Tokyo Neighborhoods, Lauren Koerner

USF Tampa Graduate Theses and Dissertations

This thesis asks, are neighborhood demographic and economic variables connected to COVID-19 infection rates in Tokyo, Japan? I hypothesize that variation in urbanization and neighborhood demographics account for Japan’s low, though not uniform COVID-19 infection rates. This thesis applies several anthropological perspectives: The biocultural perspective because I look at epidemiology of COVID 19 considering socio-cultural, economic, and ecological factors as well as biological susceptibilities. The critical biocultural perspective because I look at how structures of power and inequality may impact health and healthcare access. Biomedical/applied anthropology, well placed to study the current epidemiologic situation of COVID 19 in Japan and …

Antibiotic-Resistant Escherichia Coli And EnterococcusSpp. In Sand And Water At Tampa Bay Beaches, Jennifer K. Sabater

USF Tampa Graduate Theses and Dissertations

As antibiotic resistance in the environment continues to rise there is an increased concern that infections may become harder to treat as bacteria acquire genes for multidrug resistance. Recreational beach waters in the Tampa Bay area are routinely monitored by the Florida Department of Environmental Protection for the presence of fecal indicator bacteria (FIB) such as Escherichia coli and enterococci. Exceedances of beach action values (BAV) 235 CFU/100 mL (E. coli) and 70 CFU/100 mL (enterococci) indicate the presence of fecal contamination which is associated with an increased risk of disease for beachgoers. Antibiotic-resistant E. coli and Enterococcus spp. have …

Machine Learning Approach For Cardiovascular Risk And Coronary Artery Calcification Score, C. R. Aditya, Naveen C. Sattaru, Kumaraguruparan Gopal, R. Rahul, G. Chandra Shekara, Omaima Nasif, Sulaiman Ali Alharbi, S.S. Raghavan, S. Arockia Jayadhas

School of Medical and Biological Sciences Faculty Publications and Presentations

Coronary artery calcification (CAC) could assist in the discovery of new risk elements for coronary artery disorder. CAC evaluation, on the other hand, is difficult due to the wide range of CAC in the populations. As a reason, evaluating and analysing data among research have become complicated. In the Research of Inherited Risk Factors for Coronary Atherosclerosis, we used CAC information to test the effects of different analytical methodologies on the correlation with recognized cardiovascular risk elements in asymptomatic patients. Cardiac computed tomography (CT) is also seeing an increase in examinations, and machine learning (ML) could assist with the growing …

Complete Genome Sequence Of Klebsiella Quasipneumoniae Subsp. Similipneumoniae Strain If3sw-P1, Isolated From The International Space Station, Natasha S. Sushenko, Nitin K. Singh, Daniel L. Vellone, Scott W. Tighe, Brian P. Hedlund, Kasthuri Venkateswaran, Duane P. Moser

Life Sciences Faculty Research

The 5.2-Mb circular genome of Klebsiella quasipneumoniae subsp. similipneumoniae strain IF3SW-P1, isolated from the International Space Station, was sequenced using Oxford Nanopore Technologies. The genome lacks a megaplasmid typical of hypervirulent and multidrug-resistant Klebsiella strains but does contain a chromosomally encoded OqxAB efflux pump associated with carbapenem resistance.

Afro-Latinx And Afro-Latin Americans In The United States: Examining Ethnic And Racial Experiences In Higher Education, Glenda Maria Vaillant Cruz

USF Tampa Graduate Theses and Dissertations

Education research in the United States has vastly excluded Afro-Latinx and Afro-Latin American college students from the canon. Afro-Latinx and Afro-Latin American college students are presented with unique challenges and opportunities for identity exploration and development at the university level. As Schwartz, Kurtines, and Montgomery argue, higher education institutions extend emerging adulthood or the period in which individuals explore identities and develop a sense of self (Shwartz, Kurtines, and Montgomery 2005). Education research in the United States has historically centered around US-based racial formation, suggesting that Blackness and Latinness are mutually exclusive, what researchers Christopher Busey and Carolyn Silva refer …

Assessing Environmental Sensitivity In San Diego County, California, For Bird Species Of Special Concern, Eda Okan Kilic

USF Tampa Graduate Theses and Dissertations

It is widely recognized that desertification constitutes one of the biggest environmental problems on Earth. Desertification negatively impacts the future of humans and other living things all over the globe. Therefore, the assessment of desertification is essential to both monitor and combat desertification. A number of models are routinely applied to assess desertification. The MEDALUS model is one of the most popular approaches, identifying desertification risk based on an environmentally sensitive area index (ESAI) that integrates climate, vegetation, soils, groundwater, and socio-economic factors to obtain an overall rating. The goal of this study was to measure the potential impacts of …

Improving Operating Room Turnover Time Through Process Redesign, Kevan Wright

DNP and Student Works

Average turnover times for general surgery for the previous three months were analyzed retrospectively. This quality improvement project aimed to reduce turnover times by eliminating inefficiencies, removing redundant tasks, designating specific team member roles, and standardizing the process. This was accomplished through parallel processing.

Racial And Ethnic Disparities In Postpartum Care In The Greater Boston Area During The Covid-19 Pandemic, Tianyue Mi, Peiyin Hung, Xiaoming Li Ph.D., Alecia Mcgregor, Jinggui He, Jie Zhou

Faculty Publications

IMPORTANCE Racial and ethnic disparities in postpartum care access have been well identified in the United States. Such disparities could be exacerbated by the COVID-19 pandemic because of amplified economic distress and compromised social capital among pregnant women who belong to racial or ethnic minority groups.

OBJECTIVE To examine whether the COVID-19 pandemic is associated with an increase in the existing racial and ethnic disparity in postpartum care access.

DESIGN, SETTING, AND PARTICIPANTS This was a retrospective cohort study using electronic health records data. Multinomial logistic regressions in an interrupted time series approach were used to assess monthly changes in …

Newsroom, Georgia Southern University

Newsroom (2006-2023)

• Georgia Southern names Dominique A. Quarles as Associate Vice President for Inclusive Excellence and Chief Diversity Officer

Post-Discharge And Long-Term Follow-Up After An Acute Coronary Syndrome: International Collaborative Group Of Cncf Position Paper, Pierre Sabouret, Gilles Lemesle, Anne Bellemain-Appaix, Pierre Aubry, Pier-Paolo Bocchino, Erik Rafflenbeul, Loïc Belle, Jim Nolan, Marco Bernardi, Giuseppe Biondi-Zoccai, Michael P. Savage, Maciej Banach, Guillaume Cayla

Division of Cardiology Faculty Papers

Introduction: Long-term follow-up after an acute coronary syndrome (ACS) presents a crucial challenge due to the high residual cardiovascular risk and the potential for major bleeding events. Although several treatment strategies are available, this article focuses on patients who have undergone percutaneous coronary intervention (PCI) for ACS, which is a frequent clinical situation. This position paper aims to support physicians in daily practice to improve the management of ACS patients.

Material and methods: A group of recognized international and French experts in the field provides an overview of current evidence-based recommendations - supplemented by expert opinion where such evidence is …

The Gut Microbiome-Brain Crosstalk In Neurodegenerative Diseases, Laura Ghezzi, Claudia Cantoni, Emanuela Rotondo, Daniela Galimberti

2020-Current year OA Pubs

The gut-brain axis (GBA) is a complex interactive network linking the gut to the brain. It involves the bidirectional communication between the gastrointestinal and the central nervous system, mediated by endocrinological, immunological, and neural signals. Perturbations of the GBA have been reported in many neurodegenerative diseases, suggesting a possible role in disease pathogenesis, making it a potential therapeutic target. The gut microbiome is a pivotal component of the GBA, and alterations in its composition have been linked to GBA dysfunction and CNS inflammation and degeneration. The gut microbiome might influence the homeostasis of the central nervous system homeostasis through the …

Hematopoietic Stem And Progenitor Cell Maintenance And Multiple Lineage Differentiation Is An Integral Function Of Nfatc1, Carlotta Barahona De Brito, S Klein-Hessling, Edgar Serfling, Amiya Kumar Patra

Peninsula Medical School

AbstractHematopoietic stem and progenitor cell (HSPC) maintenance and the differentiation of various lineages is a highly complex but precisely regulated process. Multiple signaling pathways and an array of transcription factors influence HSPC maintenance and the differentiation of individual lineages to constitute a functional hematopoietic system. Nuclear factor of activated T cell (NFAT) family transcription factors have been studied in the context of development and function of multiple mature hematopoietic lineage cells. However, until now their contribution in HSPC physiology and HSPC differentiation to multiple hematopoietic lineages has remained poorly understood. Here, we show that NFAT proteins, specifically NFATc1, play an …

Multidrug Resistance In Cancer: Understanding Molecular Mechanisms, Immunoprevention And Therapeutic Approaches, Talha Bin Emran, Asif Shahriar, Aar Rafi Mahmud, Tanjilur Rahman, Mehedy Hasan Abir, Mohd Faijanur-Rob Siddiquee, Hossain Ahmed, Nova Rahman, Firzan Nainu, Elly Wahyudin

School of Medicine Publications

Cancer is one of the leading causes of death worldwide. Several treatments are available for cancer treatment, but many treatment methods are ineffective against multidrug-resistant cancer. Multidrug resistance (MDR) represents a major obstacle to effective therapeutic interventions against cancer. This review describes the known MDR mechanisms in cancer cells and discusses ongoing laboratory approaches and novel therapeutic strategies that aim to inhibit, circumvent, or reverse MDR development in various cancer types. In this review, we discuss both intrinsic and acquired drug resistance, in addition to highlighting hypoxia- and autophagy-mediated drug resistance mechanisms. Several factors, including individual genetic differences, such as …

Paired Associative Stimulation Applied To The Cortex Can Increase Resting-State Functional Connectivity: A Proof Of Principle Study, Andrew Hooyman, Alexander Garbin, Beth E. Fisher, Jason J. Kutch, Carolee J. Winstein

Physical Therapy Faculty Articles and Research

Introduction
There is emerging evidence that high Beta coherence (hBc) between prefrontal and motor corticies, measured with resting-state electroencephalography (rs-EEG), can be an accurate predictor of motor skill learning and stroke recovery. However, it remains unknown whether and how intracortical connectivity may be influenced using neuromodulation. Therefore, a cortico–cortico PAS (ccPAS) paradigm may be used to increase resting-state intracortical connectivity (rs-IC) within a targeted neural circuit.

Purpose
Our purpose is to demonstrate proof of principle that ccPAS can be used to increase rs-IC between a prefrontal and motor cortical region.

Methods
Eleven non-disabled adults were recruited (mean age 26.4, sd …

The Three Two-Pore Channel Subtypes From Rabbit Exhibit Distinct Sensitivity To Phosphoinositides, Voltage, And Extracytosolic Ph, Xinghua Feng, Jian Xiong, Weijie Cai, Jin-Bin Tian, Michael X Zhu

Faculty, Staff and Student Publications

Two pore channels (TPCs) are implicated in vesicle trafficking, virus infection, and autophagy regulation. As Na+- or Ca2+-permeable channels, TPCs have been reported to be activated by NAADP, PI(3,5)P2, and/or high voltage. However, a comparative study on the function and regulation of the three mammalian TPC subtypes is currently lacking. Here, we used the electrophysiological recording of enlarged endolysosome vacuoles, inside-out and outside-out membrane patches to examine the three TPCs of rabbit (Oryctolagus cuniculus, or Oc) heterologously expressed in HEK293 cells. While PI(3,5)P2 evoked Na+ currents with a potency order of OcTPC1 > OcTPC3 > OcTPC2, only OcTPC2 displayed a strict dependence …

Phosphatidylserine And Phosphatidylethanolamine Asymmetry Have A Negligible Effect On The Global Structure, Dynamics, And Interactions Of The Kras Lipid Anchor

Faculty, Staff and Student Publications

The intrinsically disordered C-terminus of the prominent oncogenic protein KRAS-4B (KRAS) selectively interacts and clusters with phosphatidylserine (PS) lipids in the plasma membrane (PM). This 11-residue segment, called tK, contains a polybasic domain (PBD) of six contiguous lysine residues and a farnesylated cysteine. Previous molecular dynamics (MD) simulation studies of tK in phosphatidylcholine (PC)/PS bilayers have suggested that backbone conformational dynamics modulate tK-PS interactions. These simulations have been conducted in symmetric membranes whereas the PM is compositionally asymmetric, with the inner leaflet, where KRAS is localized, being enriched with PS and phosphatidylethanolamine (PE) lipids. To examine if bilayer asymmetry affects …

A Survey On Machine Learning And Internet Of Medical Things-Based Approaches For Handling Covid-19: Meta-Analysis, Shahab S. Band, Sina Ardabili, Atefeh Yarahmadi, Bahareh Pahlevanzadeh, Adiqa Kausar Kiani, Amin Beheshti, Hamid Alinejad-Rokny, Iman Dehzangi, Arthur Chang, Amir Mosavi, Massoud Moslehpour

Research Outputs: 2025-Present

Early diagnosis, prioritization, screening, clustering, and tracking of patients with COVID-19, and production of drugs and vaccines are some of the applications that have made it necessary to use a new style of technology to involve, manage, and deal with this epidemic. Strategies backed by artificial intelligence (A.I.) and the Internet of Things (IoT) have been undeniably effective to understand how the virus works and prevent it from spreading. Accordingly, the main aim of this survey is to critically review the ML, IoT, and the integration of IoT and ML-based techniques in the applications related to COVID-19, from the diagnosis …

Molecular Modelling A Key Method For Potential Therapeutic Drug Discovery, Omar Karkoutly, Anupam Dhasmana, Vijian Dhevan, Subhash C. Chauhan, Manish Tripathi

School of Medicine Publications

The well-defined and characterized 3D crystal structure of a protein is important to explore the topological and physiological features of the protein. The distinguished topography of a protein helps medical chemists design drugs on the basis of the pharmacophoric features of the protein. Structure-based drug discovery, specifically for pathological proteins that cause a higher risk of disease, takes advantage of this fact. Current tools for studying drug-protein interactions include physical, chromatographic, and electrophoretic methods. These techniques can be separated into either non-spectroscopic (equilibrium dialysis, ultrafiltration, ultracentrifugation, etc.) or spectroscopic (Fluorescence spectroscopy, NMR, X-ray diffraction, etc.) methods. These methods, however, can …

Adolescent Health Risk Behaviors, Adverse Experiences, And Self-Reported Hunger: Analysis Of 10 States From The 2019 Youth Risk Behavior Surveys, Kathryn L. Krupsky, Sarah Silwa, Hilary Seligman, Andrea D. Brown, Angela D. Liese Ph.D., Zewditu Demissie, Ellen Barnidge

Faculty Publications

We examined associations between adolescent self-reported hunger, health risk behaviors, and adverse experiences during the 2018–2019 school year. Youth Risk Behavior Survey data were pooled from 10 states. Prevalence ratios were calculated, and we assessed effect measure modification by sex. The prevalence of self-reported hunger was 13%. Self-reported hunger was associated with a higher prevalence of every health risk behavior/adverse experience analyzed, even after adjusting for sex, grade, and race/ethnicity. Sex did not modify associations. Findings underscore needs for longitudinal research with more robust measures of adolescent food insecurity to clarify the temporality of relationships.

The Hilltop Review, Vol 13, No. 1, Spring 2022, Listiani Eran

The Hilltop Review

No abstract provided.

Ictc12 Abstract Book, Bowling Green State University

International Conference on Toxic Cyanobacteria (2022)

Abstract book for the 12th International Conference on Toxic Cyanobacteria.

Metadata Best Practices For Trans And Gender Diverse Resources, Trans Metadata Collective, Jasmine Burns, Michelle Cronquist, Jackson Huang, Devon Murphy, K. J. Rawson, Beck Schaefer, Jamie Simons, Brian M. Watson, Adrian Williams

Librarian Publications & Presentations

This document is the result of a year of work and collaboration by the Trans Metadata Collective (TMDC; https://transmetadatacollective.org/), a group of dozens of cataloguers, librarians, archivists, scholars, and information professionals with a concerted interest in improving the description and classification of trans and gender diverse people in GLAMS (Galleries, Libraries, Archives, Museums and Special Collections). The Collective’s primary goal was to develop a set of best practices for the description, cataloguing, and classification of information resources as well as the creation of metadata about trans and gender diverse people, including authors and other creators.

We Are ... Marshall, June 22, 2022, Office Of Marshall University Communications

We Are ... Marshall: the Newsletter for Marshall University 1999-2023

No abstract provided.

Ms 146 Guide To Thomas Matney, Phd Papers (1929-2011), Thomas Matney (1928-2010)

Manuscript Finding Aids

The Thomas Matney papers includes materials from 1926 through 2011 relating to Dr. Matney’s research in genetics, Dr. Matney’s teaching materials, and his research as a community activist into the support and well being of at-risk children. Professor Matney made important contributions to scientific understanding of cancer-causing agents and the genetic mechanisms that underlie the development of cancer. See more at MS 146.

The Influence Of Sex On Cognitive Control Performance And Frontoparietal Network Integrity In First Episode Psychosis, Kaitlyn Mcfarlane Greer

Theses and Dissertations

Cognitive deficits in first-episode psychosis (FEP) are well documented including deficits in cognitive control, but how sex may influence or impact these cognitive deficits is not well known. Cognitive deficits may impact multiple neural networks, including the fronto-parietal network (FPN). How sex may influence the structural integrity of regions in the FPN is also an important area of research in FEP that may provide further insight into the beginnings of the disease. The current study aimed to examine sexual dimorphisms in structural integrity of the frontoparietal network (FPN) and its role in cognitive control in FEP. A total of 111 …

Silos In Higher Education Institutions: Shifting From Organizational Phenomena To A Practical Framework For Equitable Decision-Making, Mandi Sue Mizuta

Dissertations and Theses

As higher education has evolved, administrative and support functions have become more stratified and specialized, creating institutions with complex and compartmentalized organizational structures known as silos. These silos have a detrimental impact on institutions, employees, and ultimately the student stakeholders that they serve. Silos within higher education administration support services are readily acknowledged anecdotally; however, robust research to describe this phenomenon and actionable resources to address it are lacking. This multi-paper dissertation explores the theoretical implications and practical applications for using collaborative, intentional approaches to address what is argued to be at its core is a matter of equity. The …

‘Bunkering Down’: How One Community Is Tightening Social-Ecological Network Structures In The Face Of Global Change, Michele L. Barnes, Lorien Jasny, Andrew Bauman, Jon Ben, Ramiro Berardo, Örjan Bodin, Josh Eli Cinner, David A. Feary, Angela M. Guerrero, Fraser A. Januchowski-Hartley, John T. Kuange, Jacqueline D. Lau, Peng Wang, Jessica Zamborain-Mason

Marine & Environmental Sciences Faculty Articles

1. Complex networks of relationships among and between people and nature (social-ecological networks) play an important role in sustainability; yet, we have limited empirical understanding of their temporal dynamics.
2. We empirically examine the evolution of a social-ecological network in a common-pool resource system faced with escalating social and environmental change over the past two decades.
3. We first draw on quantitative and qualitative data collected between 2002 and 2018 in a Papua New Guinean reef fishing community to provide contextual evidence regarding the extent of social and environmental change being experienced. We then develop a temporal multilevel exponential random graph model using …

Advance Trends In Targeting Homology-Directed Repair For Accurate Gene Editing: An Inclusive Review Of Small Molecules And Modified Crispr-Cas9 Systems, Forough Shams, Hadi Bayat, Omid Mohammadian, Somayeh Mahboudi, Hassan Vahidnezhad, Mohsen Soosanabadi, Azam Rahimpour

Jefferson Institute of Molecular Medicine Papers and Presentations

Introduction: Clustered regularly interspaced short palindromic repeat and its associated protein (CRISPR-Cas)-based technologies generate targeted modifications in host genome by inducing site-specific double-strand breaks (DSBs) that can serve as a substrate for homology-directed repair (HDR) in both in vitro and in vivo models. HDR pathway could enhance incorporation of exogenous DNA templates into the CRISPR-Cas9-mediated DSB site. Owing to low rate of HDR pathway, the efficiency of accurate genome editing is diminished. Enhancing the efficiency of HDR can provide fast, easy, and accurate technologies based on CRISPR-Cas9 technologies. Methods: The current study presents an overview of attempts conducted on the …

Why Are There So Many Mosquitoes?, Alan L. Gillen, Savannah Childs, Megan Goin, Karly Mckinney

Faculty Publications and Presentations

Mosquitoes have been challenging man and animals alike since the fall.Mosquitoes number in the trillions worldwide. Not only is the mosquito a nuisance with the constant buzz around your ear, they also are the primary vector of many dangerous diseases including the West Nile Virus (WNV). WNV has become a more prominent mosquito-transmitted disease in the United States and more specifically in Colorado, Texas, and other states in the Midwest. While commonly found in the genus Culex, WNV and other diseases can be found in differentgenera of mosquito, including Aedes and Anopheles. While these two are not themost common regarding …

Bilateral Upper Extremity Motor Priming (Bump) Plus Task-Specific Training For Severe, Chronic Upper Limb Hemiparesis: Study Protocol For A Randomized Clinical Trial, Mary Ellen Stoykov, Olivia M Biller, Alexandra Wax, Erin King, Jacob M Schauer, Louis F Fogg, Daniel M Corcos

Department of Occupational Therapy Faculty Papers

BACKGROUND: Various priming techniques to enhance neuroplasticity have been examined in stroke rehabilitation research. Most priming techniques are costly and approved only for research. Here, we describe a priming technique that is cost-effective and has potential to significantly change clinical practice. Bilateral motor priming uses the Exsurgo priming device (Exsurgo Rehabilitation, Auckland, NZ) so that the less affected limb drives the more affected limb in bilateral symmetrical wrist flexion and extension. The aim of this study is to determine the effects of a 5-week protocol of bilateral motor priming in combination with task-specific training on motor impairment of the affected …