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Articles 10951 - 10980 of 32278
Full-Text Articles in Entire DC Network
Herstory& Female Identity: Postmodern Feminist Revision Of Female Characters In Islamic Narrative In Mohja Kahf’S Hagar Poems, Aya Elbably
Dentistry
Contending with the re-reading and re-writing of history that has always excluded women from its grand narratives, postmodern feminist writers have always sought to revise canonical texts from a gynocentric perspective. Through their revisionary fiction, they aimed at challenging the subordinate, marginal and invisible position of the women characters in these texts. In place of the alleged objectivity of these accounts, postmodern feminist revisionist writers transform these ancient tales while employing female insight to re-narrate the story of humanity, yet through women’s perspective. Thus, they create new texts to challenge the fundamental gender stereotypes, namely the binary images generated by …
Pharmacy Newsletter : July 2022, Pharmacy Department
Pharmacy Newsletter : July 2022, Pharmacy Department
Department of Pharmacy Archives
Content:
- TOX TOK! Liquid Nicotine Used in E-Cigarettes can Harm Children
- Monkey Pox FAQs
- Clinical Understanding of Different Formulations of Tenofovir: TDF Versus TAF
- Fluids And Electrolytes Maintenance Calculation In Pediatric Patients
- A NEW Warning : FDA recommends thyroid monitoring in babies and young children who receive injections of iodine-containing contrast media(ICM) for medical imaging.
- CHOLERA
- The 2 Million Dollar Injection
- Retinoic Acid Preparations & their Differ
Prophetic Eu: Prospective Identification Of Pneumonia In Hospitalized Patients In The Intensive Care Unit In European And United States Cohorts, Stephen P. Bergin, Sara B. Calvert, John Farley, Jie-Lena Sun, Karen Chiswell, Willem Dieperink, Jan Kluytmans, Juan Carlos Lopez-Delgado, Rafael Leon-Lopez, Marcus J. Zervos, Marin H. Kollef, Matthew Sims, Badih A. Kabchi, Daniel Rubin, Jonas Santiago, Mukil Natarajan, Pamela Tenaerts, Vance G. Fowler, Thomas L. Holland, Marc J. Bonten, Sebastiaan J. Hullegie
Prophetic Eu: Prospective Identification Of Pneumonia In Hospitalized Patients In The Intensive Care Unit In European And United States Cohorts, Stephen P. Bergin, Sara B. Calvert, John Farley, Jie-Lena Sun, Karen Chiswell, Willem Dieperink, Jan Kluytmans, Juan Carlos Lopez-Delgado, Rafael Leon-Lopez, Marcus J. Zervos, Marin H. Kollef, Matthew Sims, Badih A. Kabchi, Daniel Rubin, Jonas Santiago, Mukil Natarajan, Pamela Tenaerts, Vance G. Fowler, Thomas L. Holland, Marc J. Bonten, Sebastiaan J. Hullegie
Infectious Diseases Articles
Background: The prospective identification of patients at high risk for hospital-acquired/ventilator-associated bacterial pneumonia may improve clinical trial feasibility and foster antibacterial development. In a prior study conducted in the United States, clinical criteria were used to prospectively identify these patients; however, these criteria have not been applied in a European population.
Methods: Adults considered high risk for pneumonia (treatment with ventilation or high levels of supplemental oxygen) in the intensive care units of 7 European hospitals were prospectively enrolled from June 12 to December 27, 2017. We estimated the proportion of high-risk patients developing pneumonia according to US Food and …
2022 - 2023 University Catalog, Loma Linda University
2022 - 2023 University Catalog, Loma Linda University
University Catalog (2005 - present)
This is a one-year CATALOG, effective beginning Summer Quarter 2022.
Volume 112, Number 1, July 2022
External Funding Bulletin, January - June 2022, Uno Office Of Research And Creative Activity
External Funding Bulletin, January - June 2022, Uno Office Of Research And Creative Activity
Sponsored Programs Bulletins
No abstract provided.
How Environmental Litigation Has Turned Pipelines Into Pipe Dreams, Madison Hinkle, Jesse J. Richardson
How Environmental Litigation Has Turned Pipelines Into Pipe Dreams, Madison Hinkle, Jesse J. Richardson
Law Faculty Scholarship
Proposed oil and gas pipelines have faced a myriad of legal challenges in the past several years. Even where pipeline proponents have prevailed, the cost and delay of protracted litigation has often caused cancellation of pipeline projects. In addition, presidential transitions have led to abrupt reversals of pipeline policies, which courts have often reviewed skeptically. This Article explores the regulatory framework for pipeline construction and analyzes recent lawsuits, describing the legal requirements that agencies must follow to change policies and discussing policies of the Obama and Trump Administrations in context of the legal challenges. It concludes by analyzing the approaches …
Effects Of Combined Gentamicin And Furosemide Treatment On Cochlear Macrophages, Liana Sargsyan, Austin R Swisher, Alisa P Hetrick, Hongzhe Li
Effects Of Combined Gentamicin And Furosemide Treatment On Cochlear Macrophages, Liana Sargsyan, Austin R Swisher, Alisa P Hetrick, Hongzhe Li
Faculty, Staff and Student Publications
Combining aminoglycosides and loop diuretics often serves as an effective ototoxic approach to deafen experimental animals. The treatment results in rapid hair cell loss with extended macrophage presence in the cochlea, creating a sterile inflammatory environment. Although the early recruitment of macrophages is typically neuroprotective, the delay in the resolution of macrophage activity can be a complication if the damaged cochlea is used as a model to study subsequent therapeutic strategies. Here, we applied a high dose combination of systemic gentamicin and furosemide in
Breast Cancer-Caps: A Breast Cancer Screening System Based On Capsule Network Utilizing The Multiview Breast Thermal Infrared Images, Devanshu Tiwari, Manish Dixit, Kamlesh Gupta
Breast Cancer-Caps: A Breast Cancer Screening System Based On Capsule Network Utilizing The Multiview Breast Thermal Infrared Images, Devanshu Tiwari, Manish Dixit, Kamlesh Gupta
Turkish Journal of Electrical Engineering and Computer Sciences
This paper proposed an accurate and fully automated breast cancer early screening system called the "Breast Cancer-Caps". The capsule network is used in this approach for the cancer detection in breast utilizing the thermal infrared images for the first time. This capsule network is trained with the help of Dynamic as well as Static breast thermal images dataset consisting of left, right, frontal views along with a new multiview thermal images. These multiview breast thermal images are fabricated by concatenating the conventional left, frontal and right view breast thermal images. The other current and popular deep transfer learning models such …
Automatic Keyword Assignment System For Medical Research Articles Using Nearest-Neighbor Searches, Fati̇h Di̇lmaç, Adi̇l Alpkoçak
Automatic Keyword Assignment System For Medical Research Articles Using Nearest-Neighbor Searches, Fati̇h Di̇lmaç, Adi̇l Alpkoçak
Turkish Journal of Electrical Engineering and Computer Sciences
Assigning accurate keywords to research articles is increasingly important concern. Keywords should be selected meticulously to describe the article well since keywords play an important role in matching readers with research articles in order to reach a bigger audience. So, improper selection of keywords may result in less attraction to readers which results in degradation in its audience. Hence, we designed and developed an automatic keyword assignment system (AKAS) for research articles based on k-nearest neighbor (k-NN) and threshold-nearest neighbor (t-NN) accompanied with information retrieval systems (IRS), which is a corpus-based method by utilizing IRS using the Medline dataset in …
A New Automatic Bearing Fault Size Diagnosis Using Time-Frequency Images Of Cwt And Deep Transfer Learning Methods, Yilmaz Kaya, Fatma Kuncan, Hüseyi̇n Meti̇n Ertunç
A New Automatic Bearing Fault Size Diagnosis Using Time-Frequency Images Of Cwt And Deep Transfer Learning Methods, Yilmaz Kaya, Fatma Kuncan, Hüseyi̇n Meti̇n Ertunç
Turkish Journal of Electrical Engineering and Computer Sciences
Bearings are generally used as bearings or turning elements. Bearings are subjected to high loads and rapid speeds. Furthermore, metal-to-metal contact within the bearing makes it sensitive. In today?s machines, bearing failures disrupt the operation of the system or completely stop the system. Bearing failures that can occur can cause enormous damage to the entire system. Therefore, it is necessary to anticipate bearing failures and to carry out a regular diagnostic examination. Various systems have been developed for fault diagnosis. In recent years, deep transfer learning (DTL) methods are often preferred in current bearing diagnosis models, as they provide time …
Analysis Of Tissue Electrical Properties On Bio-Impedance Variation Of Upper Limps, Enver Salkim
Analysis Of Tissue Electrical Properties On Bio-Impedance Variation Of Upper Limps, Enver Salkim
Turkish Journal of Electrical Engineering and Computer Sciences
Upper limb loss has a significant impact on individual socioeconomic life. Human-machine interface (HMI) using surface electromyography (sEMG) establishes a link between the user and a hand prosthesis to recognize hand gestures and motions which allows the control of robotic machines and prostheses to perform dexterous tasks. Numerous methods aimed to enhance hand gesture and motion recognition toward an HMI. Bio-impedance analysis (BIA) is a noninvasive way of assessing body compositions and has been recently used for hand motion interpretation using `brute force? pattern recognition. The impedance variation in the body mostly depends on the precise stimulation using appropriate electrical …
Protecting Free Speech And Due Process Values On Dominant Social Media Platforms, Dawn Carla Nunziato
Protecting Free Speech And Due Process Values On Dominant Social Media Platforms, Dawn Carla Nunziato
UC Law Journal
Dominant social media platforms have been increasingly perceived as engaging in discrimination against conservative and right-wing viewpoints. Trump’s deplatforming, coupled with the platforms’ recent removal of Covid- and election-related misinformation, led to cries of censorship by conservatives and increased calls for regulation of the platforms. Supreme Court Justice Thomas took up this charge, suggesting a regulatory path forward for lawmakers seeking to hold the platforms liable for alleged viewpoint discrimination and censorship.
This Article examines the desirability and constitutionality of recent legislative initiatives that seek to provide remedies for these alleged ills and to rein in the dominant platforms’ discretion …
Institutional Choice For Software Safety Standards, Bryan H. Choi
Institutional Choice For Software Safety Standards, Bryan H. Choi
UC Law Journal
The pursuit of software safety standards has stalled. In response, commentators and policymakers have looked increasingly to federal agencies to deliver new hope. Some place their faith in existing agencies while others propose a new super agency to oversee software-specific issues. This turn reflects both optimism in the agency model as well as pessimism in other institutions such as the judiciary or private markets.
This Essay argues that the agency model is not a silver bullet. Applying a comparative institutional choice lens, this Essay explains that the characteristic strengths of the agency model—expertise, uniformity, and efficiency—offer less advantage than one …
Interannual Variation In Climate Contributes To Contingency In Post-Fire Restoration Outcomes In Seeded Sagebrush Steppe, Allison B. Simler-Williamson, Cara Applestein, Matthew J. Germino
Interannual Variation In Climate Contributes To Contingency In Post-Fire Restoration Outcomes In Seeded Sagebrush Steppe, Allison B. Simler-Williamson, Cara Applestein, Matthew J. Germino
Biology Faculty Publications and Presentations
Interannual variation, especially weather, is an often-cited reason for restoration “failures”; yet its importance is difficult to experimentally isolate across broad spatiotemporal extents, due to correlations between weather and site characteristics. We examined post-fire treatments within sagebrush-steppe ecosystems to ask: (1) Is weather following seeding efforts a primary reason why restoration outcomes depart from predictions? and (2) Does the management-relevance of weather differ across space and with time since treatment? Our analysis quantified range-wide patterns of sagebrush (Artemisia spp.) recovery, by integrating long-term records of restoration and annual vegetation cover estimates from satellite imagery following thousands of post-fire seeding …
Photocrosslinking Probes Proximity Of Thymine Modifiers Tethering Excitonically Coupled Dye Aggregates To Dna Holliday Junction, Shibani Basu, Keitel Cervantes-Salguero, Bernard Yurke, William B. Knowlton, Jeunghoon Lee, Olga A. Mass
Photocrosslinking Probes Proximity Of Thymine Modifiers Tethering Excitonically Coupled Dye Aggregates To Dna Holliday Junction, Shibani Basu, Keitel Cervantes-Salguero, Bernard Yurke, William B. Knowlton, Jeunghoon Lee, Olga A. Mass
Chemistry and Biochemistry Faculty Publications and Presentations
A DNA Holliday junction (HJ) has been used as a versatile scaffold to create a variety of covalently templated molecular dye aggregates exhibiting strong excitonic coupling. In these dye-DNA constructs, one way to attach dyes to DNA is to tether them via single long linkers to thymine modifiers incorporated in the core of the HJ. Here, using photoinduced [2 + 2] cycloaddition (photocrosslinking) between thymines, we investigated the relative positions of squaraine-labeled thymine modifiers in the core of the HJ, and whether the proximity of thymine modifiers correlated with the excitonic coupling strength in squaraine dimers. Photocrosslinking between squaraine-labeled thymine …
Branched-Chain Amino Acids And Their Interactions With Lipid Metabolites For Increased Risk Of Gestational Diabetes, Ninghua Li, Jing Li, Hui Wang, Jinnan Liu, Weiqin Li, Kai Yang, Xiaoxu Huo, Junhong Leng, Zhijie Yu, Gang Hu, Zhongze Fang, Xilin Yang
Branched-Chain Amino Acids And Their Interactions With Lipid Metabolites For Increased Risk Of Gestational Diabetes, Ninghua Li, Jing Li, Hui Wang, Jinnan Liu, Weiqin Li, Kai Yang, Xiaoxu Huo, Junhong Leng, Zhijie Yu, Gang Hu, Zhongze Fang, Xilin Yang
Population and Public Health Science Faculty Publications
Objective: We aimed to explore associations of branched-chain amino acids (BCAA) in early pregnancy with gestational diabetes mellitus (GDM), and whether high BCAAs and lipidomics markers had interactive effects on the risk of GDM. Methods: We conducted a 1:1 case-control study (n=486) nested in a prospective cohort of pregnant women in Tianjin, China. Blood samples were collected at their first antenatal care visit (median 10 gestational weeks). Serum BCAAs, saturated fatty acids (SFA) and lysophosphatidylcholines (LPC) were measured by liquid chromatography-tandem mass spectrometry analysis. Conditional logistic regression was performed to examine associations of BCAAs with the risk of GDM. Interactions …
Planetary-Scale Change To The Biosphere Signalled By Global Species Translocations Can Be Used To Identify The Anthropocene, Mark Williams, Reinhold Leinfelder, Anthony D. Barnosky, Martin J. Head, Francine M.G. Mccarthy, Alejandro Cearreta, Stephen Himson, Rachael Holmes, Colin N. Waters, Jan Zalasiewicz, Simon Turner, Mary Mcgann, Elizabeth A. Hadly, M. Allison Stegner, Paul Michael Pilkington, Jérôme Kaiser, Juan Carlos Berrio, Ian P. Wilkinson, Jens Zinke, Kristine L. Delong
Planetary-Scale Change To The Biosphere Signalled By Global Species Translocations Can Be Used To Identify The Anthropocene, Mark Williams, Reinhold Leinfelder, Anthony D. Barnosky, Martin J. Head, Francine M.G. Mccarthy, Alejandro Cearreta, Stephen Himson, Rachael Holmes, Colin N. Waters, Jan Zalasiewicz, Simon Turner, Mary Mcgann, Elizabeth A. Hadly, M. Allison Stegner, Paul Michael Pilkington, Jérôme Kaiser, Juan Carlos Berrio, Ian P. Wilkinson, Jens Zinke, Kristine L. Delong
Faculty Publications
We examine three distinctive biostratigraphic signatures of humans associated with hunting and gathering, landscape domestication and globalization. All three signatures have significant fossil records of regional importance that can be correlated inter-regionally and help describe the developing pattern of human expansion and appropriation of resources. While none have individual first or last appearances that provide a globally isochronous marker, all three signatures overlap stratigraphically, in that they are part of a continuum of change, with complex regional patterns. Here we show that during the later stages of globalization, late nineteenth to twentieth century records of species translocations can be used …
Enhancing A Qubo Solver Via Data Driven Multi-Start And Its Application To Vehicle Routing Problem, Whei Yeap Suen, Matthieu Parizy, Hoong Chuin Lau
Enhancing A Qubo Solver Via Data Driven Multi-Start And Its Application To Vehicle Routing Problem, Whei Yeap Suen, Matthieu Parizy, Hoong Chuin Lau
Research Collection School Of Computing and Information Systems
Quadratic unconstrained binary optimization (QUBO) models have garnered growing interests as a strong alternative modelling framework for solving combinatorial optimization problems. A wide variety of optimization problems that are usually studied using conventional Operations Research approaches can be formulated as QUBO problems. However, QUBO solvers do not guarantee optimality when solving optimization problems. Instead, obtaining high quality solutions using QUBO solvers entails tuning of multiple parameters. Here in our work, we conjecture that the initial states adjustment method used in QUBO solvers can be improved, where careful tuning will yield overall better results. We propose a data-driven multi-start algorithm that …
Demographic Expansions And The Emergence Of Host Specialization In Genetically Distinct Ecotypes Of The Tick-Transmitted Bacterium Anaplasma Phagocytophilum, Matthew L. Aardema, Nina V. Bates, Qiana E. Archer, Friederike D.Von Loewenich
Demographic Expansions And The Emergence Of Host Specialization In Genetically Distinct Ecotypes Of The Tick-Transmitted Bacterium Anaplasma Phagocytophilum, Matthew L. Aardema, Nina V. Bates, Qiana E. Archer, Friederike D.Von Loewenich
Department of Biology Faculty Scholarship and Creative Works
In Europe, genetically distinct ecotypes of the tick-vectored bacterium Anaplasma phagocytophilum circulate among mammals in three discrete enzootic cycles. To date, potential ecological factors that contributed to the emergence of these divergent ecotypes have been poorly studied. Here, we show that the ecotype that predominantly infects roe deer (Capreolus capreolus) is evolutionarily derived. Its divergence from a host generalist ancestor occurred after the last glacial maximum as mammal populations, including roe deer, recolonized the European mainland from southern refugia. We also provide evidence that this host specialist ecotype's effective population size (Ne) has tracked changes in the population of its …
Pastoral Liturgy 52 (3) Complete Journal
Whalers In “A Post-Whaling World”: Sustainable Conservation Of Marine Mammals And Sustainable Development Of Whaling Communities—With A Case Study From The Eastern Caribbean, Russell Fielding
Honors College Faculty Publications
The sustainable conservation of marine mammals depends not only upon considerations made for the marine mammals themselves. In many parts of the world, human societies have developed a deep reliance upon marine mammals as a food source. The sustainability and the equitable, sustainable development of these communities should be considered alongside efforts to conserve the marine mammals upon which people rely. As an example of the complexity inherent to simultaneous efforts on both fronts, this paper reviews and synthesizes two lines of research related to a small-scale whaling operation for odontocetes (dolphins and toothed whales) based in the Eastern Caribbean. …
Juvenile Homicide Offenders: A Life-Course Perspective, Norair Khachatryan
Juvenile Homicide Offenders: A Life-Course Perspective, Norair Khachatryan
USF Tampa Graduate Theses and Dissertations
Murder by offenders under the age of 18 is a cause for public concern, despite the overall decrease in the rate of juvenile-perpetrated homicide since 1994. Due to several rulings by the U.S. Supreme Court (i.e., Miller v. Alabama, 2012), the likelihood that convicted juvenile homicide offenders (JHOs) will be released from prison has increased. Accordingly, it is important to examine these offenders’ long-term readjustment to society after their release. Using a mixed-method approach, the present study was designed to explore the factors that influence whether JHOs reoffend and their reoffending patterns, over a period of approximately 35 years. Another …
Optimization Of Nozzle, Application Height, And Speed For Uass Pesticide Applications, Trenton Houston
Optimization Of Nozzle, Application Height, And Speed For Uass Pesticide Applications, Trenton Houston
Department of Agronomy and Horticulture: Dissertations, Theses, and Student Research
Unmanned aerial spray systems (UASS) applications have the potential to be efficient pesticide application platforms under conditions that are not accessible or fit for typical pesticide application equipment. Although this type of application is still under development in the United States, UASS pesticide applications are common in Asia, as they have replaced backpack sprayers. There is limited literature on the optimization of UASS applications and many parameters need to be investigated to identify the best combination of application variables such as flight height, flight speed, and nozzle selection. The objectives were to identify the deposition patterns of a four rotor …
Age- And Sex-Based Differences In The Moral Intuitions Of American Early Adolescents, Brandon Bretl, Marlon Goering
Age- And Sex-Based Differences In The Moral Intuitions Of American Early Adolescents, Brandon Bretl, Marlon Goering
Education Faculty Publications and Presentations
This study sought to explore the validity of a latent-factor model of moral intuition development during early adolescence. The 3-Factor Character Foundations Survey (CFS-3) was used to assess the moral intuitions of early adolescents (n = 850, mean = 12.4 years old, SD = 0.96) under a moral foundations theory framework. Confirmatory factor analysis supported the psychometric validity of the three latent factor constructs (autonomy, loyalty and empathy), and partial metric invariance was established to allow for the comparison of latent factor means between four age- and sex-based groups coinciding with averages for pubertal onset. Results support prior findings of …
Social Perception Of Systemic Risks, Pia Johanna Schweizer, Robert Goble, Ortwin Renn
Social Perception Of Systemic Risks, Pia Johanna Schweizer, Robert Goble, Ortwin Renn
Sustainability and Social Justice
The article distinguishes between two types of risks: conventional and systemic risks. Conventional risks can be contained in space and time, follow linear cause–effect relationships and can be addressed with effective and pointed interventions into the cause–effect chain. Systemic risks, however, are characterized by high complexity, transboundary effects, stochastic relationships, nonlinear cause–effect patterns with tipping points, and are often associated with less public attention than they require. The article addresses the reasons why systemic risks seem to be attenuated in public perception. The article goes on to consider how the social amplification of risk framework is useful in the context …
Food Justice And Urban Agriculture: Using City Spaces To Foster Equity, Jessica Giese
Food Justice And Urban Agriculture: Using City Spaces To Foster Equity, Jessica Giese
School of Education and Leadership Student Capstone Theses and Dissertations
In an increasingly urban society, urban agriculture creates opportunities to address inequalities in access to healthy foods and bridge gaps in our food systems. While solving the problems of food and environmental injustice demands large-scale changes at a systemic level, urban agriculture can promote community engagement, education, and sovereignty, empowering city residents to gain control over their resources and access to nutritious foods. This research seeks to explain how two very different urban agricultural projects are impacting their communities through access, engagement, and education. Intersections Food Forest is a neighborhood project that utilizes an empty city lot to cultivate perennial …
A Black Woman’S Road To Principalship: An Autoethnography, Daria Caldwell
A Black Woman’S Road To Principalship: An Autoethnography, Daria Caldwell
School of Education and Leadership Student Capstone Theses and Dissertations
This study investigates the perceived barriers of Black women in educational leadership. Majority of the research in the educational field pertaining to women is generalized in various ways and are not specific to Black women. With Black women in educational leadership on the rise, more research is needed for and by Black women to help successfully navigate educational leadership. During the last decade, African American women have pioneered and forged new frontiers as educational leaders (Rusher, 1996). This study included four Black women in educational leadership in different school districts in Minnesota. Data was collected through semi-structured interviews as well …
Emergence Activity At Hibernacula Differs Among Four Bat Species Affected By White-Nose Syndrome, Reilly T. Jackson, Emma V. Wilcox, John M. Zobel, Riley F. Bernard
Emergence Activity At Hibernacula Differs Among Four Bat Species Affected By White-Nose Syndrome, Reilly T. Jackson, Emma V. Wilcox, John M. Zobel, Riley F. Bernard
Biological Sciences Faculty Publications and Presentations
Prior to the introduction of white-nose syndrome (WNS) to North America, temperate bats were thought to remain within hibernacula throughout most of the winter. However, recent research has shown that bats in the southeastern United States emerge regularly from hibernation and are active on the landscape, regardless of their WNS status. The relationship between winter activity and susceptibility to WNS has yet to be explored but warrants attention, as it may enable managers to implement targeted management for WNS-affected species. We investigated this relationship by implanting 1346 passive integrated transponder (PIT) tags in four species that vary in their susceptibility …
Normalizing Reproductive Genetic Innovation, Myrisha S. Lewis
Normalizing Reproductive Genetic Innovation, Myrisha S. Lewis
Faculty Publications
Many societally accepted techniques were quite controversial at inception and for decades after. For example, historically, dialysis was “unnatural,” vaccination was “the poisoned quill,” and artificial insemination was akin to adultery. Despite social and cultural hurdles, the aforementioned medical techniques have today attained overall public acceptance, permissive legal treatment, and even health insurance coverage in some cases.
Unlike many now-routine treatments like in vitro fertilization (IVF), egg freezing, and organ transplantation, which flourished without significant governmental intervention, today’s controversial medical treatments, especially those involving reproductive genetic innovation, face intense regulatory barriers. Reproductive genetic innovation, which is the combination of IVF …
Dose-Related Effects Of Ketamine For Antidepressant-Resistant Symptoms Of Posttraumatic Stress Disorder In Veterans And Active Duty Military: A Double-Blind, Randomized, Placebo-Controlled Multi-Center Clinical Trial, Chadi G Abdallah, John D Roache, Ralitza Gueorguieva, Lynnette A Averill, Stacey Young-Mccaughan, Paulo R Shiroma, Prerana Purohit, Antoinette Brundige, William Murff, Kyung-Heup Ahn, Mohamed A Sherif, Eric J Baltutis, Mohini Ranganathan, Deepak D'Souza, Brenda Martini, Steven M Southwick, Ismene L Petrakis, Rebecca R Burson, Kevin B Guthmiller, Argelio L López-Roca, Karl A Lautenschlager, John P Mccallin, Matthew B Hoch, Alexandar Timchenko, Sergio E Souza, Charles E Bryant, Jim Mintz, Brett T Litz, Douglas E Williamson, Terence M Keane, Alan L Peterson, John H Krystal
Dose-Related Effects Of Ketamine For Antidepressant-Resistant Symptoms Of Posttraumatic Stress Disorder In Veterans And Active Duty Military: A Double-Blind, Randomized, Placebo-Controlled Multi-Center Clinical Trial, Chadi G Abdallah, John D Roache, Ralitza Gueorguieva, Lynnette A Averill, Stacey Young-Mccaughan, Paulo R Shiroma, Prerana Purohit, Antoinette Brundige, William Murff, Kyung-Heup Ahn, Mohamed A Sherif, Eric J Baltutis, Mohini Ranganathan, Deepak D'Souza, Brenda Martini, Steven M Southwick, Ismene L Petrakis, Rebecca R Burson, Kevin B Guthmiller, Argelio L López-Roca, Karl A Lautenschlager, John P Mccallin, Matthew B Hoch, Alexandar Timchenko, Sergio E Souza, Charles E Bryant, Jim Mintz, Brett T Litz, Douglas E Williamson, Terence M Keane, Alan L Peterson, John H Krystal
Staff and Researcher Publications
This study tested the efficacy of repeated intravenous ketamine doses to reduce symptoms of posttraumatic stress disorder (PTSD). Veterans and service members with PTSD (n = 158) who failed previous antidepressant treatment were randomized to 8 infusions administered twice weekly of intravenous placebo (n = 54), low dose (0.2 mg/kg; n = 53) or standard dose (0.5 mg/kg; n = 51) ketamine. Participants were assessed at baseline, during treatment, and for 4 weeks after their last infusion. Primary analyses used mixed effects models. The primary outcome measure was the self-report PTSD Checklist for DSM-5 (PCL-5), and secondary outcome …