Digital Commons Network^™

Perspectives On Wider Integration Of The Health-Assistive Smart Home, Gordana Dermody, Jenna Mikus, Davina Porock, Dov Sugarman, Naeem K. Janjua, Christopher How, Roschelle Fritz

Research outputs 2022 to 2026

Most older adults desire to be as independent as possible and remain living in their ancestral home as they age. Aging-in-place maximizes the independence of older adults, enhancing their wellbeing and quality of life while decreasing the financial burden of residential care costs. However, due to chronic disease, multimorbidity, and age-related changes, appropriate conditions are required to make aging-in-place possible. Remote monitoring with smart home technologies could provide the infrastructure that enables older adults to remain living independently in their own homes safely. The health-assistive smart home shows great promise, but there are challenges to integrating smart homes on a …

Statistical Analysis Plan For The Stepped-Wedge Clinical Trial Healing Right Way - Enhancing Rehabilitation Services For Aboriginal Australians After Brain Injury, Elizabeth Armstrong, Tapan Rai, Deborah Hersh, Sandra Thompson, Juli Coffin, Natalie Ciccone, Leon Flicker, Dominique Cadilhac, Erin Godecke, Deborah Woods, Colleen Hayward, Graeme J. Hankey, Meaghan Mcallister, Judith Katzenellenbogen

Research outputs 2022 to 2026

Background: Aboriginal Australians are known to suffer high levels of acquired brain injury (stroke and traumatic brain injury) yet experience significant barriers in accessing rehabilitation services. The aim of the Healing Right Way trial is to evaluate a culturally secure intervention for Aboriginal people with newly acquired brain injury to improve their rehabilitation experience and quality of life. Following publication of the trial protocol, this paper outlines the statistical analysis plan prior to locking the database. Methods: The trial involves a stepped wedge design with four steps over 3 years. Participants were 108 adult Aboriginal Australians admitted to one of …

Deep Learning Inspired Feature Engineering For Classifying Tremor Severity, Ahmed Al Taee, Seyedehmarzieh Hosseini, Rami N. Khushaba, Tanveer Zia, Chin-Teng Lin, Adel Al-Jumaily

Research outputs 2022 to 2026

Bio-signals pattern recognition systems can be impacted by several factors with a potential to limit their associated performance and clinical translation. Among these factors, selecting the optimum feature extraction method, that can effectively exploit the interaction between the temporal and spatial information, is the most prominent. Despite the potential of deep learning (DL) models for extracting temporal, spatial, or temporal-spatial information, they are typically restricted by their need for a large amount of training data. The deep wavelet scattering transform (WST) is a relatively recent advancement within the DL literature to replace expensive convolution neural networks models with computationally less …

Pre-Service Teachers' Use Of Ict To Collaborate To Complete Assessment Tasks, Eileen V. Slater, Donna Barwood, Zina Cordery

Research outputs 2022 to 2026

This research explored the use of ICT products by n = 123 pre-service teachers to complete collaborative assessments. Students responded to a questionnaire relating to the use, benefits and limitations, and what would better enable the use of ICT for collaborative assessment purposes. The ICT products favoured by students did not support some key elements necessary for online collaboration, through either student use or product functionality. Poor Internet access was a commonly cited limitation with the effect of reducing access to available ICT skills training. Suggestions for changes to course structure and content and further research are made.

Squat And Countermovement Jump Performance Across A Range Of Loads: A Comparison Between Smith Machine And Free Weight Execution Modes In Elite Sprinters, Irineu Loturco, Michael R. Mcguigan, Tomás T. Freitas, Fábio Y. Nakamura, Daniel A. Boullosa, Pedro L. Valenzuela, Lucas A. Pereira, Fernando Pareja-Blanco

Research outputs 2022 to 2026

The aims of this study were to: 1) provide and compare the height achieved during Smith machine (SM) and free weight (FW) loaded jumps executed over a wide spectrum of loads (40–120 % of body mass [BM]); and 2) test the difference between loaded and unloaded squat jump (SJ) and countermovement jump (CMJ) attempts in ten highly trained male sprinters. On the first visit, athletes performed unloaded SJ and CMJ, loaded SJ with loads corresponding to 40, 60, 80, 100, and 120 % BM, and loaded CMJ at 100% BM using an Olympic barbell (FW). On the second visit, they …

The Effects Of Home-Based Exercise Therapy For Breast Cancer-Related Fatigue Induced By Radical Radiotherapy, Georgios Mavropalias, Prue Cormie, Carolyn J. Peddle-Mcintyre, Daniel A. Galvão, Dennis R. Taaffe, Christelle Schofield, Sharon Ray, Yvonne Zissiadis, Robert U. Newton

Research outputs 2022 to 2026

Background: Radiotherapy (RT) can lead to cancer-related fatigue (CRF) and decreased health-related quality of life (HRQoL) in breast cancer patients. The purpose of this trial was to examine the feasibility and efficacy of a home-based resistance and aerobic exercise intervention for reducing CRF and improving HRQoL in breast cancer patients during RT. Methods: Women with breast cancer (N = 106) commencing RT were randomized to 12 weeks of home-based resistance and aerobic exercise (EX) or usual care/control (CON). The primary endpoint was CRF, with secondary endpoints of HRQoL, sleep duration and quality, and physical activity. Measurements were undertaken prior to …

Anatomy Of An Internet Hijack And Interception Attack: A Global And Educational Perspective, Ben A. Scott, Michael N. Johnstone, Patryk Szewczyk

Research outputs 2022 to 2026

The Internet’s underlying vulnerable protocol infrastructure is a rich target for cyber crime, cyber espionage and cyber warfare operations. The stability and security of the Internet infrastructure are important to the function of global matters of state, critical infrastructure, global e-commerce and election systems. There are global approaches to tackle Internet security challenges that include governance, law, educational and technical perspectives. This paper reviews a number of approaches to these challenges, the increasingly surgical attacks that target the underlying vulnerable protocol infrastructure of the Internet, and the extant cyber security education curricula; we find the majority of predominant cyber security …

Revisiting The Interval And Fuzzy Topsis Methods: Is Euclidean Distance A Suitable Tool To Measure The Differences Between Fuzzy Numbers?, Hosein Arman, Abdollah Hadi-Vencheh, Reza Kiani Mavi, Mehdi Khodadadipour, Ali Jamshidi

Research outputs 2022 to 2026

Euclidean distance (ED) calculates the distance between n-coordinate points that n equals the dimension of the space these points are located. Some studies extended its application to measure the difference between fuzzy numbers (FNs).This study shows that this extension is not logical because although an n-coordinate point and an FN are denoted the same, they are conceptually different. An FN is defined by n components; however, n is not equal to the dimension of the space where the FN is located. This study illustrates this misapplication and shows that the ED between FNs does not necessarily reflect their difference. We …

Exploring Discordant Low Amyloid Beta And High Neocortical Tau Positron Emission Tomography Cases, Natasha Krishnadas, Vincent Doré, Simon M. Laws, Tenielle Porter, Fiona Lamb, Svetlana Bozinovski, Victor L. Villemagne, Christopher C. Rowe

Research outputs 2022 to 2026

Introduction: Neocortical 3R4R (3-repeat/4-repeat) tau aggregates are rarely observed in the absence of amyloid beta (Aβ). 18F-MK6240 binds specifically to the 3R4R form of tau that is characteristic of Alzheimer's disease (AD). We report four cases with negative Aβ, but positive tau positron emission tomography (PET) findings. Methods: All Australian Imaging, Biomarkers and Lifestyle study of aging (AIBL) study participants with Aβ (18F-NAV4694) and tau (18F-MK6240) PET scans were included. Centiloid < 25 defined negative Aβ PET (Aβ–). The presence of neocortical tau was defined quantitatively and visually. Results: Aβ– PET was observed in 276 participants. Four of these participants (one cognitively unimpaired [CU], two mild cognitive impairment [MCI], one AD) had tau tracer retention in a pattern consistent with Braak tau stages V to VI. Fluid biomarkers supported a diagnosis of AD. In silico analysis of APP, PSEN1, PSEN2, and MAPT genes did not identify relevant functional mutations. Discussion: Discordant cases were infrequent (1.4% of all Aβ– participants). In these cases, the Aβ PET ligand may not be detecting the Aβ that is present.

Plasma P217+Tau Versus Nav4694 Amyloid And Mk6240 Tau Pet Across The Alzheimer's Continuum, Vincent Doré, James D. Doecke, Ziad S. Saad, Gallen Triana-Baltzer, Randy Slemmon, Natasha Krishnadas, Pierrick Bourgeat, Kun Huang, Samantha Burnham, Christopher Fowler, Stephanie R. Rainey-Smith, Ashley I. Bush, Larry Ward, Jo Robertson, Ralph N. Martins, Colin L. Masters, Victor L. Villemagne, Jurgen Fripp, Hartmuth C. Kolb, Christopher C. Rowe

Research outputs 2022 to 2026

Introduction: We evaluated a new Simoa plasma assay for phosphorylated tau (P-tau) at aa217 enhanced by additional p-tau sites (p217+tau). Methods: Plasma p217+tau levels were compared to 18F-NAV4694 amyloid beta (Aβ) positron emission tomography (PET) and 18F-MK6240 tau PET in 174 cognitively impaired (CI) and 223 cognitively unimpaired (CU) participants. Results: Compared to Aβ− CU, the plasma levels of p217+tau increased 2-fold in Aβ+ CU and 3.5-fold in Aβ+ CI. In Aβ− the p217+tau levels did not differ significantly between CU and CI. P217+tau correlated with Aβ centiloids P =.67 (CI, P =.64; CU, P =.45) and tau SUVRMT P …

Edge-Iiotset: A New Comprehensive Realistic Cyber Security Dataset Of Iot And Iiot Applications For Centralized And Federated Learning, Mohamed A. Ferrag, Othmane Friha, Djallel Hamouda, Leandros Maglaras, Helge Janicke

Research outputs 2022 to 2026

In this paper, we propose a new comprehensive realistic cyber security dataset of IoT and IIoT applications, called Edge-IIoTset, which can be used by machine learning-based intrusion detection systems in two different modes, namely, centralized and federated learning. Specifically, the dataset has been generated using a purpose-built IoT/IIoT testbed with a large representative set of devices, sensors, protocols and cloud/edge configurations. The IoT data are generated from various IoT devices (more than 10 types) such as Low-cost digital sensors for sensing temperature and humidity, Ultrasonic sensor, Water level detection sensor, pH Sensor Meter, Soil Moisture sensor, Heart Rate Sensor, Flame …

The Career Resilience Of Senior Women Managers: A Cross-Cultural Perspective, Uma Jogulu, Esmé Franken

Research outputs 2022 to 2026

This article examines how cultural contexts influence the demonstration of resilient behaviors of women senior managers in large organizations. We compare the experiences of Malaysian and Australian women overcoming key challenges and obstacles in their career journeys by engaging in the resilience strategies of network leveraging, learning, and adaptability. Our findings reveal the unique, complex, and contextual nature of career resilience, and show how resilience can be demonstrated, often differently, across culture and context. Our study adds to the existing body of literature in the areas of careers, gender in the workplace, and resilience, by highlighting how senior women sustain …

An Initial Investigation Into Parental Perceptions Surrounding The Impact Of Mobile Media Use On Child Behavior And Executive Functioning, Stephanie C. Milford, Lynette Vernon, Joseph J. Scott, Nicola F. Johnson

Research outputs 2022 to 2026

Children demonstrate increasing early engagement with mobile media facilitated by its portability and interactivity. Parents are known to employ a range of mediation strategies for mobile media use but continue to have limited awareness about the impact of mobile media on their child’s executive functioning. Mobile media use has previously been shown to be negatively correlated with the executive functioning development of a child; however, little is known of how parents approach their child’s mobile media use. This study employed a survey design (N = 281) to examine how parents access information related to mobile media and document their perspectives …

Exercise Recommendations For People With Bone Metastases: Expert Consensus For Healthcare Providers And Clinical Exercise Professionals, Kristin L. Campbell, Prue Cormie, Sarah Weller, Shabbir M. H. Alibhai, Kate A. Bolam, Anna Campbell, Andrea L. Cheville, Mary-Ann Dalzell, Nicolas H. Hart, Celestia S. Higano, Kirstin Lane, Sami Mansfield, Margaret L. Mcneely, Robert U. Newton, Morten Quist, Jennifer Rauw, Friederike Rosenberger, Daniel Santa Mina, Kathryn H. Schmitz, Kerri M. Winters-Stone, Joachim Wiskemann, Jennifer Goulart

Research outputs 2022 to 2026

Purpose: Exercise has been underutilized in people with advanced or incurable cancer despite the potential to improve physical function and reduce psychosocial morbidity, especially for people with bone metastases because of concerns over skeletal complications. The International Bone Metastases Exercise Working Group (IBMEWG) was formed to develop best practice recommendations for exercise programming for people with bone metastases on the basis of published research, clinical experience, and expert opinion. Methods: The IBMEWG undertook sequential steps to inform the recommendations: (1) modified Delphi survey, (2) systematic review, (3) cross-sectional survey to physicians and nurse practitioners, (4) in-person meeting of IBMEWG to …

Identifying Effective Interventions To Promote Consumption Of Protein-Rich Foods From Lower Ecological Footprint Sources: A Systematic Literature Review, Rimante Ronto, Golsa Saberi, Gianna Maxi Leila Robbers, Stephanie Godrich, Mark Lawrence, Shawn Somerset, Jessica Fanzo, Josephine Chau

Research outputs 2022 to 2026

Addressing overconsumption of protein-rich foods from high ecological footprint sources can have positive impacts on health such as reduction of non-communicable disease risk and protecting the natural environment. With the increased attention towards development of ecologically sustainable diets, this systematic review aimed to critically review literature on effectiveness of those interventions aiming to promote protein-rich foods from lower ecological footprint sources. Five electronic databases (Medline, Web of Science, Scopus, Embase and Global Health) were searched for articles published up to January 2021. Quantitative studies were eligible for inclusion if they reported on actual or intended consumption of protein-rich animal-derived and/or …

Rapid Triage For Ischemic Stroke: A Machine Learning-Driven Approach In The Context Of Predictive, Preventive And Personalised Medicine, Yulu Zheng, Zheng Guo, Yanbo Zhang, Jianjing Shang, Leilei Yu, Ping Fu, Yizhi Liu, Xingang Li, Hao Wang, Ling Ren, Wei Zhang, Haifeng Hou, Xuerui Tan, Wei Wang, Global Health Epidemiology Reference Group (Gherg)

Research outputs 2022 to 2026

Background

Recognising the early signs of ischemic stroke (IS) in emergency settings has been challenging. Machine learning (ML), a robust tool for predictive, preventive and personalised medicine (PPPM/3PM), presents a possible solution for this issue and produces accurate predictions for real-time data processing.

Methods

This investigation evaluated 4999 IS patients among a total of 10,476 adults included in the initial dataset, and 1076 IS subjects among 3935 participants in the external validation dataset. Six ML-based models for the prediction of IS were trained on the initial dataset of 10,476 participants (split participants into a training set [80%] and an internal …

5-Ht2 Receptor Antagonism Reduces Human Motoneuron Output To Antidromic Activation But Not To Stimulation Of Corticospinal Axons, Jacob R. Thorstensen, Janet L. Taylor, Justin J. Kavanagh

Research outputs 2022 to 2026

The intrinsic electrical properties of motoneurons strongly affect motoneuron excitability to fast-acting excitatory ionotropic inputs. Serotonin (5-HT) is a neurochemical that alters the intrinsic properties of motoneurons, whereby animal models and in vitro experiments indicate that 5-HT increases motoneuron excitability by activating 5-HT2 receptors on the somato-dendritic compartment. In the current study, we examined how antagonism of the 5-HT2 receptor affects motoneuron excitability in humans. We hypothesised that motoneuron excitability would be reduced. The 5-HT2 antagonist cyproheptadine was administered to 10 healthy participants in a double-blinded, placebo-controlled, crossover trial. Electrical cervicomedullary stimulation was used to deliver a synchronised excitatory volley …

Epidemiology Of ∆8thc-Related Carcinogenesis In Usa: A Panel Regression And Causal Inferential Study, Albert Stuart Reece, Gary Kenneth Hulse

Research outputs 2022 to 2026

The use of ∆8THC is increasing at present across the USA in association with widespread cannabis legalization and the common notion that it is “legal weed”. As genotoxic actions have been described for many cannabinoids, we studied the cancer epidemiology of ∆8THC. Data on 34 cancer types was from the Centers for Disease Control Atlanta Georgia, substance abuse data from the Substance Abuse and Mental Health Services Administration, ethnicity and income data from the U.S. Census Bureau, and cannabinoid concentration data from the Drug Enforcement Agency, were combined and processed in R. Eight cancers (corpus uteri, liver, gastric cardia, breast …

Fine-Grained Ship Image Recognition Based On Bcnn With Inception And Am-Softmax, Zhilin Zhang, Ting Zhang, Zhaoying Liu, Peijie Zhang, Shanshan Tu, Yujian Li, Muhammad Waqas

Research outputs 2022 to 2026

The fine-grained ship image recognition task aims to identify various classes of ships. However, small inter-class, large intra-class differences between ships, and lacking of training samples are the reasons that make the task difficult. Therefore, to enhance the accuracy of the fine-grained ship image recognition, we design a fine-grained ship image recognition network based on bilinear convolutional neural network (BCNN) with Inception and additive margin Softmax (AM-Softmax). This network improves the BCNN in two aspects. Firstly, by introducing Inception branches to the BCNN network, it is helpful to enhance the ability of extracting comprehensive features from ships. Secondly, by adding …

Mediation Roles Of Pedagogical Approaches And Personality Traits In Entrepreneurial Curriculum Design And Entrepreneurial Intention Nexus, Victor Fannam Nunfam, Ebenezer Afrifa-Yamoah, Akanganngang Joseph Asitik

Research outputs 2022 to 2026

Planned behaviour theory was used in a path analysis modelling to investigate the serial mediation role of teaching methods and personality traits (locus of control, need for achievement and entrepreneurial attitude) in the relationship between entrepreneurship curriculum and entrepreneurial intention among university students in Ghana. A proposed 40-item instrument was used to measure outcomes for six constructs (3 personality trait constructs, entrepreneurship curriculum, teaching methods and entrepreneurial intention) for 324 participants. Acceptable convergent, divergent and construct validity scores were observed for the instrument. Teaching methods fully mediated the first-order relationships between entrepreneurial curriculum and each personality traits. The three constructs …

Determinants Of Switching Intention In The Electricity Markets - An Integrated Structural Model Approach, Shahid Hussain, Pi-Shen Seet, Maria Ryan, Mohammad Iranmanesh, Helen Cripps, Abdul Salam

Research outputs 2022 to 2026

This study adopts an integrated approach and combines the theory of planned behavior and push-pull theory to unpack the antecedents of customer switching intention in a contextual setting (Western Australia) that has a regulated electricity market. Partial least squares structural equation modeling was used to analyze data from a survey of 405 retail electricity consumers, which reveals that perceived relative price, electronic word-of-mouth, customer-based reputation of a service provider, past switching experience, and subjective norms significantly influence attitude toward switching and switching intention. Our findings contribute to the literature on retail electricity markets by showing the importance of customer-based reputation …

“It Only Hurts When I Laugh”: Tolerating Bullying Humour In Order To Belong At Work, Barbara Plester, Tim Bentley, Emily Brewer

Research outputs 2022 to 2026

Our study examines the impacts on workers when organisational humour is repeated, sustained, dominating, and potentially harmful, and thus can be considered to be bullying. In an ethnographic study of an idiosyncratic New Zealand IT company, we observed humour that was sexualised, dominating, and perpetrated by the most powerful organizational members. We argue that the compelling need for belonging in this extreme organizational culture influenced workers to accept bullying humour as just a joke and therefore acceptable and harmless even when it contravened societal workplace norms. Our contribution is in identifying and extending the significant theoretical relationship between workplace humour …

A Retrospective Cohort Study Of Factors Associated With Severity Of Falls In Hospital Patients, Manonita Ghosh, Beverly O’Connell, Ebenezer Afrifa-Yamoah, Sue Kitchen, Linda Coventry

Research outputs 2022 to 2026

Severity of falls in hospital patients are threat to patient safety which can result in a financial burden on the patient’s family and health care services. Both patient specific and environmental and organisational factors are associated with severity of falls in hospital. It is important to continuously analyse the factors associated with severity of fall which can inform the implementation of any fall preventive strategies. This study aims to identify factors associated with the severity of falls in hospitalised adult patients in Western Australia. This study involved a retrospective cohort analysis of inpatient falls records extracted from the hospital’s Clinical …

Addressing Filicide In Ghana: Linking Cultural Understanding With The Law Against Filicide. Does The Law Work?, Alhassan Abdullah, Margarita Frederico, Felix Mensah, Hajara Bentum, Yihang Wang, Jennifer Litela Asare

Research outputs 2022 to 2026

Introduction: Consistent with international promulgation on the criminalization of filicide, Ghana’s Children’s Act 1998 (560) and the Criminal Justice Act criminalizes any form of torture against children. Yet, perpetrators of filicide in Ghana may go unpunished due to the beliefs in cultural norms that justify filicide acts. The cultural narratives of filicide can impede on the application and effectiveness of the laws of filicide. Method: The study employed a vignette approach to explore the views of 19 adults, who were parents between 69 years of age and 30 years of age, in rural and urban Ghana on the laws of …

Assessment And Monitoring Of Achilles Tendinopathy In Clinical Practice: A Qualitative Descriptive Exploration Of The Barriers Clinicians Face, Myles Calder Murphy, James Debenham, Caroline Bulsara, Paola Chivers, Ebonie Kendra Rio, Sean Docking, Mervyn Travers, William Gibson

Research outputs 2022 to 2026

Our primary objective was to explore the barriers preventing clinicians from implementing what they think is ideal practice as it relates to using tools to aid diagnosis and monitor progress in mid-portion Achilles tendinopathy. Our secondary objectives were to describe the assessments employed by clinicians in their own practice to aid with (a) diagnosis and (b) monitoring progress in Achilles tendinopathy and explore the outcome measure domains clinicians believe to be the most and least important when managing patients with Achilles tendinopathy. We employed a qualitative descriptive study design. Thirteen participants (eight female, five male) from across Australia, consisting of …

Association Of Immunoglobulin G N-Glycosylation With Carotid Atherosclerotic Plaque Phenotypes And Actual Clinical Cardiovascular Events: A Study Protocol For A Longitudinal Prospective Cohort Study, Cuihong Tian, Gehendra Mahara, Hongxia Zhang, Xuerui Tan

Research outputs 2022 to 2026

Introduction Immune-inflammatory response plays a key role in the pathogenesis of atherosclerosis. IgG N-glycosylation is reported to be associated with the 10-year atherosclerotic cardiovascular disease risk score and subclinical atherosclerosis. However, the relationship of IgG glycosylation with actual clinical cardiovascular disease (CVD) events and plaque phenotypes has rarely been investigated. Therefore, this study aims to understand whether IgG glycosylation traits are correlated with actual clinical CVD events and plaque phenotypes. Methods and analysis Designed to verify the efficacy of IgG glycosylation as a risk for CVD events and screen potential biomarkers of CVD to prevent atherosclerosis occurrence, this longitudinal prospective …

Bioturbation By Echidna (Tachyglossus Aculeatus) In A Forest Habitat, South-Western Australia, Shannon J. Dundas, Lara Osborne, Anna J. M. Hopkins, Katinka X. Ruthrof, Patricia A. Fleming

Research outputs 2022 to 2026

Bioturbation by digging animals is important for key forest ecosystem processes such as soil turnover, decomposition, nutrient cycling, water infiltration, seedling recruitment, and fungal dispersal. Despite their widespread geographic range, little is known about the role of the short-beaked echidna (Tachyglossus aculeatus) in forest ecosystems. We measured the density and size of echidna diggings in the Northern Jarrah Forest, south-western Australia, to quantify the contribution echidna make to soil turnover. We recorded an overall density of 298 echidna diggings per hectare, 21 % of which were estimated to be less than 1 month old. The average size of digs was …

Comparison Of Auditory Steady-State Responses With Conventional Audiometry In Older Adults, Hadeel Y. Tarawneh, Hamid R. Sohrabi, Wilhelmina H. A. M. Mulders, Ralph N. Martins, Dona M. P. Jayakody

Research outputs 2022 to 2026

Behavioral measures, such as pure-tone audiometry (PTA), are commonly used to determine hearing thresholds, however, PTA does not always provide reliable hearing information in difficult to test individuals. Therefore, objective measures of hearing sensitivity that require little-to-no active participation from an individual are needed to facilitate the detection and treatment of hearing loss in difficult to test people. Investigation of the reliability of the auditory steady-state response (ASSR) for measuring hearing thresholds in older adults is limited. This study aimed to investigate if ASSR can be a reliable, objective measure of frequency specific hearing thresholds in older adults. Hearing thresholds …

European Epidemiological Patterns Of Cannabis- And Substance-Related Body Wall Congenital Anomalies: Geospatiotemporal And Causal Inferential Study, Albert Stuart Reece, Gary Kenneth Hulse

Research outputs 2022 to 2026

As body wall congenital anomalies (BWCAs) have a long history of being associated with prenatal or community cannabis exposure (CCE), it was of interest to investigate these epidemiological relationships in Europe given the recent increases in cannabis use prevalence, daily intensity, and Δ9-tetrahydrocannabinol (THC) potency. Methods: This study makes use of BWCA data from Eurocat, drug exposure data from the European Monitoring Centre for Drugs and Drug Addiction, and income from the World Bank. Results: The mapping analysis showed that BWCARs increased in France, Spain, and the Netherlands. The bivariate mapping analysis showed that the BWCA rates (BWCAR) and the …

Flavonoid Intakes Inversely Associate With Copd In Smokers, Nicola P. Bondonno, Benjamin H. Parmenter, Frederik Dalgaard, Kevin Murray, Daniel Bech Rasmussen, Cecilie Kyrø, Aedin Cassidy, Catherine P. Bondonno, Joshua R. Lewis, Kevin D. Croft, Gunnar Gislason, Augustin Scalbert, Anne Tjønneland, Kim Overvad, Anja Olsen, Jonathan M. Hodgson

Research outputs 2022 to 2026

Introduction: Higher flavonoid intakes are beneficially associated with pulmonary function parameters; however, their association with chronic obstructive pulmonary disease (COPD) is unknown. This study aimed to examine associations between intakes of 1) total flavonoids, 2) flavonoid subclasses and 3) major flavonoid compounds with incident COPD in participants from the Danish Diet, Cancer and Health study. Methods: This prospective cohort included 55 413 men and women without COPD, aged 50-65 years at recruitment. Habitual flavonoid intakes at baseline were estimated from a food frequency questionnaire using Phenol-Explorer. Danish nationwide registers were used to identify incident cases of COPD. Associations were modelled …