Digital Commons Network^™

Community Campus As Threshold: A Space Of Dialogue For Academia And The Community, R Brown, P Warwick, Zoe Latham, Rachel Manning, Sebastian Stevens

School of Art, Design and Architecture

This paper explores an argument for community-situated spaces of encounter – acting as thresholds – between community and academia, through which: learning can be enhanced; a greater sense of identity and efficacy can be fostered; and a defined agency can be enabled. This proposition prioritises a dialogic relationship in a shared ground of agency and discourse, whose potential is reinforced through a rediscovery of the local arising from the Covid pandemic. The rediscovery of the local has pushed civic-minded universities pre-existing interrogation of their community-based learning practice in the context of marginalised communities; a key challenge is how to foster …

Highest Densities Of Mountain Hares ( Lepus Timidus ) Associated With Ecologically Restored Bog But Not Grouse Moorland Management, Carlos P.E. Bedson, Philip M. Wheeler, Neil Reid, Wilson Edwin Harris, David Mallon, Simon Caporn, Richard Preziosi

School of Biological and Marine Sciences

No abstract provided.

Synchronized Seed Germination And Seedling Growth Of Black Cumin, Mohammed Elsayed El-Mahrouk, Mossad Khairy Maamoun, Yaser Hassan Dewir, Antar Nasr El-Banna, Hail Z. Rihan, Ahmed Salamh, Ahmed A. Al-Aizari, Michael P. Fuller

School of Biological and Marine Sciences

Black cumin (Nigella sativa) is an important medicinal plant in the pharmacological industry. It is cultivated on a commercial scale, but its seeds have a slow, unsynchronized germination rate. Enhancing seed germination is crucial for improving the production of black cumin. The influence of presowing treatments [gibberellic acid (GA3), potassium nitrate, salicylic acid, and stratification at 4 °C] on seed germination was assessed. Seed germination was determined daily for 30 days, and germination parameters, including final germination percentage (FGP), corrected germination rate, number of days to reach 50% of FGP, and seedling length vigor index, were evaluated. Endogenous contents of …

Left Ventricular Assist Device Support And Longitudinal Sleeve Gastrectomy Combined With Diet In Bridge To Heart Transplant, Mandy Ng, Beverly Rodgers, Saadiya Rehman, Sriram S Nathan, Kulvinder S Bajwa, Shinil K Shah, Bindu H Akkanti, Marwan F Jumean, Sachin Kumar, Jennifer L Dressel, Rajko Radovancevic, Melissa M Felinski, Biswajit Kar, Igor D Gregoric

The Texas Heart Institute Journal

Combining left ventricular assist device (LVAD) implantation and longitudinal sleeve gastrectomy may enable patients with morbid obesity to lose enough weight for heart transplant eligibility. In a retrospective study, we evaluated long-term outcomes of patients with body mass indexes ≥35 who underwent LVAD implantation and longitudinal sleeve gastrectomy during the same hospitalization (from January 2013 through July 2018) and then adhered to a dietary protocol. We included 22 patients (mean age, 49.9 ± 12.5 yr; mean preoperative body mass index, 43.3 ± 6.2). Eighteen months after gastrectomy, all 22 patients were alive, and 16 (73%) achieved a body mass index …

Evaluating Provider Knowledge On The Impact Of Vitamin D Deficiency In Chronic Health Conditions, Shelly Alamry

DNP Projects

Vitamin D deficiency affects nearly one billion individuals globally. It is an essential vitamin to maintain bone health as well as the overall health of the body. Recent research reveals the significance of vitamin D deficiency in chronic health conditions like osteoporosis, depression, breast cancer, dementia, and viral infections like COVID-19. The Doctor of Nursing Practice (DNP) project aimed to evaluate if education regarding vitamin D deficiency was effective in improving provider knowledge, increases practice confidence levels, and results in self-reported practice changes. An educational session and two questionnaires were administered to healthcare providers in the state of Mississippi. Before …

Creating And Implementing A Covid-19 Prevention And Response Program In The Performing Arts: A Clinician Expertise Commentary, David Tomchuk, Kyle Schneider, Jacklyn Bascomb-Harrison

Clinical Practice in Athletic Training

No abstract provided.

Exertional Heat Stroke In A Male High School Runner With Disordered Eating: A Disablement Model Case Study, Brittni G. Hoover, Rebecca M. Hirschhorn, Allison B. Smith, Amy F. Hand

Clinical Practice in Athletic Training

A 16-year-old male high school cross country athlete collapsed at the end of an afternoon 5K cross country meet. The patient was unable to stand, and after outwardly displaying confusion and agitation, his coaches sought assistance from the athletic trainers (ATs). The patient consumed one cup of water and a granola bar on the day of the meet. The ambient air temperature was 90°F with 69% humidity. Differential diagnoses included exertional heat stroke (EHS), exertional heat exhaustion, exertional collapse associated with sickle cell trait, heat syncope, dehydration, malnutrition, and hypoglycemia. Approximately 20 minutes passed between activation of the emergency action …

Management Of Gastroesophageal Reflux Disease (Gerd) By Primary Care Providers In Mississippi, Kimberly S. Fernando, Claire E. Harrelson, Alisha D. Jones, Kasey M. Rowley, Reagan L. Walker

MSN Research Projects

Gastroesophageal reflux disease (GERD) is one of the most common diseases seen in primary care practice. To reduce the negative effects, such as esophageal narrowing, erosions, and precancerous lesions, from uncontrolled or inadequately managed GERD, primary care providers must stay up to date on evidence-based research and integrate the most current guidelines, The American College of Gastroenterology (ACG) updated guidelines for proper management of GERD in 2021, into practice. The guidelines recommend lifestyle modifications, proper pharmacological treatment with proton pump inhibitors (PPIs) for an eight-week course, and proper follow-up and/or referral if unimproved. The purpose of this research study was …

Coping Self-Efficacy As A Moderator In The Relationship Between Trauma And Disordered Eating, Bethany Owens Raymond

College of Graduate Studies: Theses & Dissertations

Disordered eating behaviors are associated with a myriad of detrimental health and mental health consequences (Ackard et al., 2003; Bryla, 2003; Karkkainen et al., 2018; Quick & Byrd-Bredbenner, 2013). Previous research identifies trauma as a risk factor for disordered eating behaviors and eating disorders (Brewerton, 2007). For instance, individuals with eating disorders are more likely to report trauma than individuals with no such history (Lejonclou et al., 2014). However, because not all individuals with a history of trauma exhibit disordered eating, it is important to identify what factors might moderate this relationship. The current study aims to investigate coping-self efficacy …

Epithelial Morphogenesis In The Drosophila Egg Chamber Requires Parvin And Ilk, Athina Keramidioti, Evgenia Golegou, Eleni Psarra, Nikolaos Paschalidis, Konstantina Kalodimou, Shinya Yamamoto, Christos Delidakis, Katerina M Vakaloglou, Christos G Zervas

Duncan NRI Faculty and Staff Publications

Integrins are the major family of transmembrane proteins that mediate cell-matrix adhesion and have a critical role in epithelial morphogenesis. Integrin function largely depends on the indirect connection of the integrin cytoplasmic tail to the actin cytoskeleton through an intracellular protein network, the integrin adhesome. What is currently unknown is the role of individual integrin adhesome components in epithelia dynamic reorganization. Drosophila egg chamber consists of the oocyte encircled by a monolayer of somatic follicle epithelial cells that undergo specific cell shape changes. Egg chamber morphogenesis depends on a developmental array of cell-cell and cell-matrix signalling events. Recent elegant work …

Emerging Roles Of Alternative Cleavage And Polyadenylation (Apa) In Human Disease, Prakash Dharmalingam, Rajasekaran Mahalingam, Hari Krishna Yalamanchili, Tingting Weng, Harry Karmouty-Quintana, Ashrith Guha, Rajarajan A Thandavarayan

Duncan NRI Faculty and Staff Publications

In the messenger RNA (mRNA) maturation process, the 3'-end of pre-mRNA is cleaved and a poly(A) sequence is added, this is an important determinant of mRNA stability and its cellular functions. More than 60%-70% of human genes have three or more polyadenylation (APA) sites and can be cleaved at different sites, generating mRNA transcripts of varying lengths. This phenomenon is termed as alternative cleavage and polyadenylation (APA) and it plays role in key biological processes like gene regulation, cell proliferation, senescence, and also in various human diseases. Loss of regulatory microRNA binding sites and interactions with RNA-binding proteins leading to …

Rethinking The Role Of Employment Barriers In Active Labor Market Policy: Evidence From A Fixed Effects Analysis, Jian Qi Tan, Irene Y. H. Ng, Kong Weng Ho

Research Collection School Of Economics

Using a panel dataset from a five-wave survey of participants in Singapore’s Work Support Programme (WSP) from 2010 to 2016, we quantify the cumulative negative impact of facing multiple employment barriers and demonstrate the association between the individual stressors and labor market indicators. Using a fixed effects model to reduce the confounding effects of unobservables, we find that a one standard deviation increase in the number of employment barriers brings about a 2.7 to 3.5 percentage point increase in the probability of being unemployed and a 58 SGD to 78 SGD decrease in individual earnings.

Therapist Self-Reported Attachment Organization And Countertransference Responses To Psychotherapy Clients, Morgan Janay Pell

Antioch University Dissertations & Theses

Therapists experience thoughts, feelings, and behaviors in response to their clients, which are sometimes referred to as countertransference. Such responses may be influenced by the therapist’s personal history, including the quality of their attachment experiences. Research has demonstrated that adult attachment organizations influence a person’s cognitive, behavioral, and affective responses toward close others, thus providing a useful framework for understanding some countertransference experiences of therapists. This quantitative study sought to add to the existing literature by examining the relationship between therapist self-reported attachment organization and countertransference responses to clients. Seventy-three therapists participated in this study, including licensed psychologists, doctorate-level psychologists, …

The Socio-Economic Factors Of Poverty: Empirical Evidence From District Lasbela, Balochistan, Fida Muhammad, Parvez Ahmed Shaikh, Hazrat Yousaf

Business Review

Poverty is defined as a lack of basic necessities for survival. The current study examines the socio-economic factors that contribute to poverty in five of the district of Lasbela's nine tehsils, namely (Bela, Dureji, Hub, Sonmiani, and Uthal. Lasbela is Balochistan's tenth most deprived district, located near Karachi. The data for this study is cross-sectional and contributed from the project's 2014 Base Line Survey (BLS, 2014). The Logit model was used to evaluate the variables under study in order to achieve the study goal. According to our empirical findings, the average daily income in this district was less than $1.50. …

Associations Between Eight Earth Observation-Derived Climate Variables And Enteropathogen Infection: An Independent Participant Data Meta-Analysis Of Surveillance Studies With Broad Spectrum Nucleic Acid Diagnostics, Josh M. Colston, Benjamin F. Zaithcik, Hamada S. Badr, Eleanor Burnett, Syed Asad Ali, Ajit Rayamajhi, Syed M. Satter, Daniel Eibach, Ralf Krumkamp, M Imran Nisar, Anita K. M. Zaidi, Zulfiqar Ahmed Bhutta

Department of Paediatrics and Child Health

Diarrheal disease, still a major cause of childhood illness, is caused by numerous, diverse infectious microorganisms, which are differentially sensitive to environmental conditions. Enteropathogen‐specific impacts of climate remain underexplored. Results from 15 studies that diagnosed enteropathogens in 64,788 stool samples from 20,760 children in 19 countries were combined. Infection status for 10 common enteropathogens—adenovirus, astrovirus, norovirus, rotavirus, sapovirus, Campylobacter, ETEC, Shigella, Cryptosporidium and Giardia—was matched by date with hydrometeorological variables from a global Earth observation dataset—precipitation and runoff volume, humidity, soil moisture, solar radiation, air pressure, temperature, and wind speed. Models were fitted for each pathogen, accounting …

Collegiate Male Athlete Attitudes Towards Male And Female Strength And Conditioning Coaches: Is There A Role For Motivation?, Shealene J. Little

EWU Masters Thesis Collection

No abstract provided.

An Asian Case Of Combined 17Α-Hydroxylase/17,20-Lyase Deficiency Due To Homozygous Pr96q Mutation: A Case Report And Review Of The Literature, Qian Liao, Rufei Shen, Mingyu Liao, Chenxi Ran, Ling Zhou, Yuling Zhang, Guiliang Peng, Zheng Sun, Hongting Zheng, Min Long

Center on Aging Staff Publications

Background: Combined 17α-hydroxylase/17,20-lyase deficiency (17-OHD) is a very rare form of congenital adrenal hyperplasia (CAH) caused by mutations in the CYP17A1 gene. Almost 100 different mutations of the CYP17A1 gene have been reported, including p.R96Q mutation, but no case of p.R96Q mutation has been described in Asian populations.

Case presentation: We describe a 22-year-old female patient of 46,XY karyotype, who presented with pseudohermaphrodism, primary amenorrhea, underdeveloped secondary sexual characteristics, delayed epiphyseal healing, hypertension, and hypokalemia. The diagnosis of 17-OHD was reached by measurement of steroid hormones and abdominal CT scan and confirmed by genetic sequencing, which revealed a homozygous p.R96Q …

Creating A Collaborative Trauma-Informed Interdisciplinary Citywide Victim Services Model Focused On Health Care For Survivors Of Human Trafficking, Juhi Jain, Mackenzie Bennett, Mark D Bailey, Daniel Liaou, Sheri-Ann O Kaltiso, Jordan Greenbaum, Kimberly Williams, Mollie R Gordon, Melissa I M Torres, Phuong T Nguyen, John H Coverdale, Victor Williams, Cayla Hari, Samantha Rodriguez, Temilola Salami, Jonell E Potter

Center for Medical Ethics and Health Policy Staff Publications

Although human trafficking is recognized as a public health issue, research on the health effects of human trafficking and best intervention practices is limited. We describe 2 citywide collaborative victim services models, the THRIVE (Trafficking, Healthcare, Resources, and Interdisciplinary Victim Services and Education) Clinic at the University of Miami and Jackson Health System in Miami, Florida, and the Greater Houston Area Pathways for Advocacy-based, Trauma-Informed Healthcare (PATH) Collaborative at Baylor College of Medicine, CommonSpirit Health, and San Jose Clinic in Houston, Texas, funded in part by the Office for Victims of Crime, which focus on trauma-informed health care delivery for …

Western Region Health & Wellness Programming Efforts: Qualitative Results From A Three-Part Listening Session, Cris L. Meier, Lily Ward, Anders Van Sandt, Sue Schneider, Riana Gayle

All Current Publications

The purpose of this project was to understand the programming efforts and experiences of Extension professionals in the Western Region of the United States. The Health and Wellness Working Group team held a series of listening sessions with a closed cohort of Extension professionals, hoping to learn from each other while also building the foundation for future collaborations and conversations about health and wellness programing in the western region.

The objectives were to understand: (1) the state of health and wellness work in the western region, including the gaps and challenges, (2) the programs that currently exist and ways that …

Safety And Efficacy Of Electrical Stimulation For Lower-Extremity Muscle Weakness In Intensive Care Unit 2019 Novel Coronavirus Patients: A Phase I Double-Blinded Randomized Controlled Trial, Alejandro Zulbaran-Rojas, Ramkinker Mishra, Naima Rodriguez, Rasha O Bara, Myeounggon Lee, Amir Behzad Bagheri, James P Herlihy, Muhammad Siddique, Bijan Najafi

Center on Aging Staff Publications

Background: Intensive care unit (ICU) prolonged immobilization may lead to lower-extremity muscle deconditioning among critically ill patients, particularly more accentuated in those with 2019 Novel Coronavirus (COVID-19) infection. Electrical stimulation (E-Stim) is known to improve musculoskeletal outcomes. This phase I double-blinded randomized controlled trial examined the safety and efficacy of lower-extremity E-Stim to prevent muscle deconditioning.

Methods: Critically ill COVID-19 patients admitted to the ICU were randomly assigned to control (CG) or intervention (IG) groups. Both groups received daily E-Stim (1 h) for up to 14 days on both gastrocnemius muscles (GNMs). The device was functional in the IG and …

Investigation Of Flow Characteristics In An Open Channel With One-Line Semicircular Vegetation Patches, Hemanta D. Karki

Theses: Doctorates and Masters

Experiments are conducted in an open channel with semi-circular patches distributed on one sidewall of the channel in which velocity distribution, turbulent intensity, and vortex generation are analyzed. The resistance force offered by a vegetation patch causes the change in water depth which have a broader application in river management, bank stabilization, and flood control.

The measurement is conducted in the laboratory with the help of different measuring devices like Laser doppler velocimeter, particle image velocimeter, measuring scale, and so on. From the experiment, the velocity distribution in a longitudinal direction suggests that the flow is fully developed after a …

Bsl2-Compliant Lethal Mouse Model Of Sars-Cov-2 And Variants Of Concern To Evaluate Therapeutics Targeting The Spike Protein, Mohanraj Manangeeswaran, Derek D C Ireland, Seth G Thacker, Ha-Na Lee, Logan Kelley-Baker, Aaron P Lewkowicz, Paul W Rothlauf, Marjorie Cornejo Pontelli, Louis-Marie Bloyet, Michael A Eckhaus, Mirian I Mendoza, Sean Whelan, Daniela Verthelyi

2020-Current year OA Pubs

Since first reported in 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is rapidly acquiring mutations, particularly in the spike protein, that can modulate pathogenicity, transmission and antibody evasion leading to successive waves of COVID19 infections despite an unprecedented mass vaccination necessitating continuous adaptation of therapeutics. Small animal models can facilitate understanding host-pathogen interactions, target selection for therapeutic drugs, and vaccine development, but availability and cost of studies in BSL3 facilities hinder progress. To generate a BSL2-compatible

Child Dietary Patterns In Homo Sapiens Evolution: A Systematic Review, Lora L Iannotti, Emmanuel A Gyimah, Miranda Reid, Melissa Chapnick, Mary Kate Cartmill, Chessa K Lutter, Charles Hilton, Theresa E Gildner, Elizabeth A Quinn

2020-Current year OA Pubs

Dietary patterns spanning millennia could inform contemporary public health nutrition. Children are largely absent from evidence describing diets throughout human evolution, despite prevalent malnutrition today signaling a potential genome-environment divergence. This systematic review aimed to identify dietary patterns of children ages 6 months to 10 years consumed before the widespread adoption of agriculture. Metrics of mention frequency (counts of food types reported) and food groups (globally standardized categories) were applied to: compare diets across subsistence modes [gatherer-hunter-fisher (GHF), early agriculture (EA) groups]; examine diet quality and diversity; and characterize differences by life course phase and environmental context defined using Köppen-Geiger …

Cardiac Immune Cell Infiltration Associates With Abnormal Lipid Metabolism, Vincenza Cifarelli, Ondrej Kuda, Kui Yang, Xinping Liu, Richard W Gross, Terri A Pietka, Gyu Seong Heo, Deborah Sultan, Hannah Luehmann, Josie Lesser, Morgan Ross, Ira J Goldberg, Robert J Gropler, Yongjian Liu, Nada A Abumrad

2020-Current year OA Pubs

CD36 mediates the uptake of long-chain fatty acids (FAs), a major energy substrate for the myocardium. Under excessive FA supply, CD36 can cause cardiac lipid accumulation and inflammation while its deletion reduces heart FA uptake and lipid content and increases glucose utilization. As a result, CD36 was proposed as a therapeutic target for obesity-associated heart disease. However, more recent reports have shown that CD36 deficiency suppresses myocardial flexibility in fuel preference between glucose and FAs, impairing tissue energy balance, while CD36 absence in tissue macrophages reduces efferocytosis and myocardial repair after injury. In line with the latter homeostatic functions, we …

Systematic Review With Meta-Analysis: Safety And Effectiveness Of Combining Biologics And Small Molecules In Inflammatory Bowel Disease, Quazim A Alayo, Osama Altayar, Matthew A Ciorba, Deborah Thomas, Parakkal Deepak, Et Al.

2020-Current year OA Pubs

BACKGROUND: Combining biologics and small molecules could potentially overcome the plateau of drug efficacy in inflammatory bowel disease (IBD). We conducted a systematic review and meta-analysis to assess the safety and effectiveness of dual biologic therapy (DBT), or small molecule combined with a biologic therapy (SBT) in IBD patients.

METHODS: We searched MEDLINE, EMBASE, Scopus, Web of Science, Cochrane Database of Systematic Reviews, and Clinical trials.gov until November 3, 2020, including studies with 2 or more IBD patients on DBT or SBT. Main outcome was safety assessed as pooled rates of adverse events (AEs) and serious AEs (SAEs) for each …

Hypertension, Rheumatoid Arthritis, And Hypothyroidism In Women Born Preterm Of The Women's Health Initiative, Pamela L. Brewer

Open Access Dissertations

Advances in perinatal and neonatal management, along with improved healthcare technologies, have increased the long-term survival of individuals who were born preterm. Millions of preterm birth survivors now reach adulthood. Premature birth, defined as birth before 37 weeks gestation, predisposes individuals to adverse health risks later in life. The Developmental Origins of Health and Disease (DOHaD) theory was used as a framework for this dissertation. The main tenets of the DOHaD theory are that early birth infers immature organ development and when coupled with maternal, neonatal, and environmental stressors, long-term health consequences and/or chronic disease may result. International studies report …

Epithelial Abnormalities In The Small Intestine Of Zambian Children With Stunting, Chola Mulenga, Sanja Sviben, Kanta Chandwe, Beatrice Amadi, Violet Kayamba, James A J Fitzpatrick, Victor Mudenda, Paul Kelly

2020-Current year OA Pubs

BACKGROUND: Environmental enteropathy (EE) contributes to impaired linear growth (stunting), in millions of children worldwide. We have previously reported that confocal laser endomicroscopy (CLE) shows fluorescein leaking from blood to gut lumen

METHODS: We performed confocal laser endomicroscopy (CLE) in 75 children and collected intestinal biopsies for histology in 91 children. CLE videos were evaluated, employing the Watson score to determine severity of leakiness. Morphometry was carried out on well-orientated mucosa and 3 biopsies were examined by electron microscopy.

RESULTS: Confocal laser endomicroscopy demonstrated substantial leakage from circulation to gut lumen in 73 (97%) children. Histology consistently showed characteristic changes …

Loss Of Function Of Wfs1 Causes Er Stress-Mediated Inflammation In Pancreatic Β-Cells, Shuntaro Morikawa, Lindsey Blacher, Chinyere Onwumere, Fumihiko Urano

2020-Current year OA Pubs

Wolfram syndrome is a rare genetic disorder characterized by juvenile-onset diabetes mellitus, optic nerve atrophy, hearing loss, diabetes insipidus, and progressive neurodegeneration. Pathogenic variants in the

Dietary Magnesium Intake And Risk Of Type 2 Diabetes Mellitus In Ghanaian Women Of Reproductive Age, Helena Bentil

Open Access Dissertations

In several studies conducted in high-income countries, low magnesium intake has been linked to an increased risk of type 2 diabetes mellitus (T2DM). However, very no studies have been conducted in Africa, where the prevalence of T2DM is increasing in many countries. Furthermore, few studies have investigated the risk of magnesium deficiency in women of reproductive age, a group where lower levels of dietary magnesium intake have been linked to gestational diabetes and pre-eclampsia during pregnancy. The purpose of this dissertation was to conduct a pilot cross-sectional study to investigate the dietary magnesium intakes of women of reproductive age in …

Impact Of A Multidisciplinary Nutritional Support Team On Quality Improvement For Patients Receiving Home Parenteral Nutrition, Michael Rothkopf, Mohan Pant, Rebecca Brown, Jaime Haselhorst, Francine Gagliardotto, Allison Tallman, Debbie Stevenson, Andrew Depalma, Michael Saracco, Dan Rosenberg, Vladimir Proudan, Kishwar Shareef, Nudrat Ayub

EVMS School of Health Professions Faculty Publications

Introduction Home parenteral nutrition (HPN) is essential for patients with intestinal failure requiring long-term nutritional support. The Amerita Quality Improvement Project for HPN Patients (QIP-PN) explored the effect of a physician nutrition expert (PNE)-led multidisciplinary nutritional support team (MNST) on HPN care for patients under its service.

Objective To determine an MNST effect on adherence to protocols, outcomes and quality of life (QOL) in HPN.

Methods The study was divided into three phases: data review (phases 1a and 1b), observation (phase 2) and intervention (phase 3). Seven Amerita locations were selected as ‘study branches’ (population), from which all study patients …