Digital Commons Network^™

Cervical Cancer In Northern Tanzania–What Do Women Living With Hiv Know, Dorah Mrema, James Samwel Ngocho, Alex Mremi, Maryam Amour, Rogathe Machange, Benjamin C Shayo, Julius P Alloyce, Evaline Ndosi, Beatus T Shirima, Device Fande, Rahma Shehoza, Emmanuel Balandya, Bruno Sunguya, Stephen E Mshana, Alfred K Mteta, Eligius Lyamuya, John Bartlett, Blandina T Mmbaga

Faculty, Staff and Students Publications

BACKGROUND: Cervical cancer (CC) is more prevalent in women living with human immunodeficiency virus (HIV) infection compared to the general population. The magnitude is high among all countries burdened with HIV-Tanzania is no exception. Despite the unprecedented risk, women living with HIV (WLHIV) may not be aware of the risk and might have unfounded beliefs thereof. This study aimed to determine the knowledge, awareness, and beliefs on CC screening among WLHIV attending a clinic at the Kilimanjaro Christian Medical Centre (KCMC) in Northern Tanzania.

METHODS: This hospital-based cross-sectional study was conducted among 327 WLHIV attending care and treatment clinic (CTC) …

New, Potent, Small Molecule Agonists Of Tyrosine Kinase Receptors Attenuate Dry Eye Disease, Zhiyuan Yu, Shaon Joy, Tianxiong Mi, Ghasem Yazdanpanah, Kevin Burgess, Cintia S De Paiva

Faculty, Staff and Students Publications

Nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), and neurotrophin3 (NT-3) bind to tyrosine kinase (Trk) receptors, TrkA, TrkB, and TrkC, respectively. This study investigated the efficacy of novel molecule agonists of Trk receptors in an in vivo model of dry eye disease (DED). Small molecule TrkC agonist (C1) and a pan-Trk agonist (pan) were synthesized for this. C57BL/6J mice were subjected to desiccating stress (DS) and received bilateral eye drops of C1, pan, or vehicle (2x/day). Dry eye signs, inflammation and expression of corneal barrier function, and conjunctival goblet cell (GC) densities were measured as part of the DED …

Reduced Pro-Inflammatory Dendritic Cell Phenotypes Are A Potential Indicator Of Successful Peanut Oral Immunotherapy, Sara Anvari, Levi B Watkin, Charles G Minard, Kimberly Schuster, Oluwatomi Hassan, Aikaterini Anagnostou, Jordan S Orange, David B Corry, Carla M Davis

Faculty, Staff and Students Publications

Dendritic cells are important mediators in the early presentation of antigen and regulation of the differentiation of T cells. Peanut oral immunotherapy (POIT) results in desensitization in most peanut allergic individuals (responders), but not in others due to allergic reactions (non-responders). Delineation of early immunologic changes contributing to desensitization would help clarify the POIT mechanism of action. We analyzed dendritic cells in 15 pediatric subjects (5-12 years) undergoing a phase 1 single-center POIT study. We examined dendritic cells at baseline, 6-, 12-, 18- and 24-weeks after initiation of POIT and responders of therapy were compared to non-responders and healthy controls. …

Endpoints In Heart Failure Drug Development, Aliza Hussain, Arunima Misra, Biykem Bozkurt

Faculty, Staff and Students Publications

Heart failure (HF) is a major health problem worldwide. The development of effective drug and/or device therapy is crucial to mitigate the significant morbidity, mortality and healthcare costs associated with HF. The choice of endpoint in clinical trials has important practical and clinical implications. Outcomes of interest including mortality and HF hospitalisations provide robust evidence for regulatory approval granted there is sufficiency of safety data. At the same time, it is important to recognise that HF patients experience significant impairments in functional capacity and quality of life, underscoring the need to incorporate parameters of symptoms and patient-reported outcomes in clinical …

A Faith For Today: Saving The Planet, Oystein S. Labianca

Faculty Publications

No abstract provided.

Pcsk9 Inhibitors In The Management Of Cardiovascular Risk: A Practical Guidance, Xiaoming Jia, Mahmoud Al Rifai, Anum Saeed, Christie M Ballantyne, Salim S Virani

Faculty, Staff and Students Publications

Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors are potent medications in the toolkit for treatment of atherosclerotic cardiovascular disease. These agents have been well studied in clinical trials supporting their efficacy in dramatically reducing low-density lipoprotein cholesterol (LDL-C) and impact on cardiovascular outcomes. Since the approval of commercial use for PCSK9 inhibitors in 2015, we have also gained significant experience in the use of these therapeutics in the real-world setting. In this article, we review current guideline recommendations, clinical trial evidence on efficacy and safety as well as data on cost-effectiveness, prescription and adherence. We focus primarily on the monoclonal …

Strategic Planning Of Electronic Resource Management: A Study Of A Smt. Hansa Mehta Library Of Msu, Baroda., Sangeeta Kamble, Mayank Trivedi Dr

Library Philosophy and Practice (e-journal)

Strategic planning helps to complete the organization's mission, vision, values, and goals. Now libraries transfer and incorporate print resources into electronic resources. The rapid growth of electronic resources in libraries urges librarians for e-resource management. This paper addresses the planning strategy for electronic resource management and the librarian's experience with planning, policy, and workflow issues regarding e-resource management. The study addresses significant steps in the process, issues, and challenges in selecting and acquiring e-resources and points out the effects of strategic planning of e-resources in the Hansa Mehta library of MSU, Baroda. It also describes the technical requirements, license, and …

Creating Community Of Young Readers During Covid-19 Lockdown: A Comprehensive Study Of A Digital Reading Platform: Storyweaver, Shaveta Azad, Rupak Chakravarty Prof.

Library Philosophy and Practice (e-journal)

Reading stories to children when they are young is the most effective way to keep them creatively engaged. Children in multilingual countries require free access to story repositories for leisure reading. In India, a country with hundreds of mother tongues, books are largely published in English and Hindi, owing to market economics. Various studies have shown that learning and reading become more important in one's mother tongue and that when a child reads in two or more languages during early years, gains a deeper understanding of language and its effective use.

In this paper, the researchers have tried to discover; …

Perception And Contribution Of Librarians To Open Access Resources In Tertiary Institutions In Ekiti State, Nigeria, Fajiwe Olabode Thomas, Adedara Judah T

Library Philosophy and Practice (e-journal)

The study investigated the perception and contribution of Librarians to Open Access Resources in tertiary institutions in Ekiti State, Nigeria. The study adopted the expo-facto descriptive design. The sampled for the study comprised 100 Librarians who were randomly selected through simple random sampling. The Role of Librarians to Open Access Resources (RLOARs),Benefits Derived from Open Access Resources (BOARs) and Challenges encountered when promoting Open Access Resources (COARs) were the three instruments used to collect relevant data for the study. The research questions raised were answered using mean and standard deviation. Means scores cut off point of 2.50 and above would …

Modeling Document Classification To Automate Mental Health Diagnosis, William M. Tadlock

EWU Masters Thesis Collection

The objective of this study is to determine if diagnosis documents can be used with document classification to automatically diagnose mental health conditions. Document classification allows text documents to be analyzed and organized into their appropriate classes based on the features and words presented in the text. One application of this is within the medical field to automatically classify different patient diagnosis based on medical or patient notes. This research applied mental health diagnosis documents to automatically diagnose a group of patients with a mental health condition based on text-based survey data. This classification was approached through several feature engineering …

Unlocking The Rusty Padlock: The Role Of The Scientific Tradition Of Pesantren Karanggedang On The Literacy Development In The Surrounding Village Community, Amri Mahbub Alfathon, Achmad Riyadi Alberto, Aldila Putri Hakmi

Library Philosophy and Practice (e-journal)

The scientific and literary construction of pesantren or Islamic boarding schools, especially traditional ones, is highly popular to the community and involves the surrounding villagers. The communication established between village community and pesantren in continuing the scientific tradition ultimately creates new socio-cultural-economic activities. Pondok Pesantren Al-Muwahidin, located in Karanggedang, Salebu Village, Majenang District, Cilacap Regency, Central Java, is one of the pesantren that has a role in developing community literacy as mentioned. This research aims to observe and explain the role of the scientific tradition of Pesantren Karanggedang on literacy development of the local village community. A case study approach …

Online Resources Utilization Of Visual And Performing Arts Undergraduates, G. F. Yasanthini, S Santharooban

Library Philosophy and Practice (e-journal)

Abstract

Even though the performance-based academic materials are useful for visual and performing arts studies, their availability is comparatively low in virtual space which makes difficult to find appropriate online resources to enrich their theoretical and practical knowledge. This study investigated the online resource utilisation and its barriers among visual and performing arts students of Swami Vipulananda Institute of Aesthetic Studies, Eastern University, Sri Lanka. A questionnaire survey was conducted among 246 randomly selected undergraduates and focus group discussion was conducted among sixteen students. The results revealed that the students mainly use social media, google applications, mobile applications and websites …

Assessment Of Information Literacy And Fake News Identification Of Benguet State University Freshmen: Implications For Library Literacy Program, Daniel Jr Balbin

Library Philosophy and Practice (e-journal)

The world is experiencing a rapid and massive spread of misinformation referred to as “infodemic” (WHO, 2020, cited by Salvi, et al., 2021). Despite information literacy had been a long-offered solution to information problems (Horton, 2007) and studies discovered that accurate identification of fake news was significantly associated with information literacy (Jones-Jang, et al., 2021), approaches to IL instruction must be updated and must adapt to the changing information society and environment (SCONUL, 2018; Rutledge and LeMire, 2017).

It aimed to determine the level of information literacy and fake news identification of the students. It also determined if there is …

The Bridwell Quarterly. Issue 14, Winter 2022, Michelle Ried

Bridwell Library Publications

No abstract provided.

Covid-19 And Education: Effects Of Integrating Mobile Devices With Undergraduate Learning Process, Moyosade Omolade Oguntuase, Oluwabunmi Dorcas Bakare

Library Philosophy and Practice (e-journal)

Abstract

The Covid-19 pandemic and the social distancing rules and lockdowns that followed have affected all aspect of our societies, including education. In order to keep education running, educational institutions have had to quickly adapt to the situation. This has resulted in an unprecedented push to online learning where mobile technologies are being used for the learning purposes. The study adopted a descriptive survey research method with a study sample of 200 undergraduate students drawn from the two colleges in Afe Babalola University, Ado Ekiti using random sampling technique. The study revealed that Telegram (67%), WhatsApp (64.5%) and Zoom (57.5%) …

Blended Or Differentiated Instruction For Inclusive Education During Post-Covid-19 Era: The Need For Upgrading School Libraries In Nigeria, Charity Onyishi

Library Philosophy and Practice (e-journal)

Abstract

With the socio-educational challenges posed by COVID-19, teaching-learning is gradually moving from face-to-face to digital and online distance learning across the world. This makes it generally challenging to meet the needs of all learners in the context of inclusive education. Increasing evidence tends to show that for effective inclusive learning, the hybrid blended approaches to learning should be differentiated. Further still is the fact that school libraries need to be upgraded with resources that meet the needs of diverse learners, and speak to the present hybridization in pedagogy and learning. A major impairing problem is the documented lack of …

Parent Involvement Towards Children’S Reading Habit: A Focus Group Survey From Nashik, India, Suvarna P. Desale, Rajendra M. Kumbhar Ph.D.

Library Philosophy and Practice (e-journal)

Abstract

Purpose - This study was carried out to ascertain parents’ attitude about reading related activities of children, to discover parents’ efforts for instilling the reading habit in their children, to understand the challenges faced by parents in inculcating reading habit in their children, and to suggest possible solutions to the parents’ difficulties related to their children’s reading habits.

Design/ Methodology - The research was conducted using the Survey method, with Focus Group Discussion used as the data collection tool. The research sample was 24 parents of pupils who were studying in the primary and secondary Marathi medium schools in …

Citizen's Arrest And Race, Ira P. Robbins

Scholarly Articles in Law Reviews & Journals

I begin with a mea culpa. In 2016, I published an article about citizen’s arrest. The idea for the article arose in 2014, when a disgruntled Virginia citizen attempted to arrest a law school professor while class was in progress. I set out to research and write a “traditional” law review article. In it, I traced the origins of the doctrine of citizen’s arrest to medieval England, imposing a positive duty on citizens to assist the King in seeking out suspected offenders and detaining them. I observed that the need for citizen’s arrest lessened with the development of organized and …

Platform-Enabled Crimes: Pluralizing Accountability When Social Media Companies Enable Perpetrators To Commit Atrocities, Rebecca Hamilton

Scholarly Articles in Law Reviews & Journals

Online intermediaries are omnipresent. Each day across the globe, the corporations running these platforms execute policies and practices that serve their profit model, typically by sustaining user engagement. Sometimes, these seemingly banal business activities enable principal perpetrators to commit crimes. Online intermediaries, however, are almost never held to account for their complicity in the resulting harms. This Article introduces the concept of platformenabled crimes into the legal literature to highlight the ways in which the ordinary business activities of online intermediaries enable the commission of crime. It then focuses on a subset of platform-enabled crimes—those in which a social media …

[Marked Confidential]: Negative Externalities Of Discovery Secrecy, Gustavo Ribeiro

Scholarly Articles in Law Reviews & Journals

Current unprecedented levels of secrecy in civil discovery create significant negative externalities by preventing our adversary system from measuring up to the broad public goals that justify it. First, excessive discovery secrecy undermines the courts and the public’s ability to correct distortions of the truth-seeking function of the adversary system caused by excessive partisanship and confirmation bias. Second, it weakens the adversary system’s promotion of liberal democratic values, such as transparency and self-government. Third, it threatens the adversary system’s role in upholding human dignity, understood either as respect or status. To correct the negative externalities caused by excessive discovery secrecy, …

An Analysis Of Cpr Performance, Self-Efficacy, And Deliberate Feedback, Caroline Martinez

Health Nutrition and Exercise Science

During sudden cardiac arrest (SCA), prompt initiation of cardiopulmonary resuscitation (CPR) by a healthcare provider or layperson is critical to a patient’s odds of survival.4 The absence of health care providers in athletic settings often leaves coaches as the primary responder in competitive or recreational athletics. The goal of this study was to determine if coaches could provide high-quality CPR. Twenty coaches completed confidence and deliberate feedback questionnaires before and after two sessions of 5 minute compression-only CPR. Data were analyzed to compare confidence pre and post CPR assessment, as well as to determine the relationship between CPR performance, self-efficacy, …

Development Of Phage Cocktails To Treate Coli Catheter-Associated Urinary Tract Infection And Associated Biofilms, Belkys C Sanchez, Emmaline R Heckmann, Sabrina I Green, Justin R Clark, Heidi B Kaplan, Robert F Ramig, Casey Hines-Munson, Felicia Skelton, Barbara W Trautner, Anthony W Maresso

Faculty, Staff and Students Publications

High rates of antimicrobial resistance and formation of biofilms makes treatment of Escherichia coli catheter-associated urinary tract infections (CAUTI) particularly challenging. CAUTI affect 1 million patients per year in the United States and are associated with morbidity and mortality, particularly as an etiology for sepsis. Phage have been proposed as a potential therapeutic option. Here, we report the development of phage cocktails that lyse contemporary E. coli strains isolated from the urine of patients with spinal cord injury (SCI) and display strong biofilm-forming properties. We characterized E. coli phage against biofilms in two in vitro CAUTI models. Biofilm viability was …

A Survey On Self-Medication For The Prevention Or Treatment Of Covid-19 And Distrust In Healthcare Of Veterans In A Primary Care Setting In The United States, Eva Amenta, Larissa Grigoryan, Laura Dillon, Casey Hines-Munson, John Van, Barbara Trautner

Faculty, Staff and Students Publications

BACKGROUND: The SARS-CoV-2 (COVID-19) pandemic brought the public overwhelming and conflicting information. Rates of trust in healthcare professionals have been declining among laypersons over the past five decades. In this setting, we sought to evaluate the use of medications, both with or without a prescription, to prevent and treat SARS-CoV-2 as well as trust in healthcare among patients in a primary care clinic.

DESIGN: We surveyed 150 veterans in primary care clinic waiting rooms at a large southwestern tertiary care Veterans Affairs hospital. This survey was performed in March-November 2021.

METHODS: The survey asked about respondents' demographics, use of medications, …

Effectiveness Of Cardiopulmonary Resuscitation Ventilation Devices With Protective Hockey Equipment As Performed By Certified Athletic Trainers, Lauren Konkol

Health Nutrition and Exercise Science

Certified Athletic Trainers (ATCs) are expected to perform cardiopulmonary resuscitation (CPR) on athletes experiencing cardiac arrest regardless of the protective equipment worn by the athlete. Additionally, ventilation devices used by ATCs aid in the delivery of ventilations during CPR. The goal of this research was to determine which ventilation device allowed ATCs to deliver adequate ventilations and to establish recommendations for helmet removal method in hockey players requiring CPR. Twenty ATCs completed four scenarios of CPR according to the 2020 AHA guidelines using a PocketMask (PM) or FaceShield (FS) to deliver ventilations and accessing the airway by removing only the …

Tracking Body Dissatisfaction And Body Ideals Of Ethnically Diverse College Women, Emma Johnson

Human Development and Family Science

Globally, women are exposed to society-created, unachievable body ideals, which change over time and are subject to influence by other, typically Western, societies. Socializing agents such as family members, peers, and media often reinforce these ideals through pressure, which can then lead to body dissatisfaction. Research on body ideals and body dissatisfaction disproportionately focuses on White women within the United States. While this group is important to continue to examine, there is a need to include women from outside of the United States and from Non-Western societies. Thus, this study examined college women’s perceptions of body ideals within and outside …

Wework: A Unicorn Company That Went Bust, Ana J. Montalvo

Socionomic Prize Winners and Events (Archived)

No abstract provided.

Pay It Forward: Realizing The Promise Of Oer For The Next Generation Of Learners, Kimberly S. Grotewold, Karen Kohler, Elisabeth M. Krimbill

Library Staff Publications (Archived)

Using Open Educational Resources to Promote Social Justice explores the opportunities and challenges of moving the discussion about open educational resources (OER) beyond affordability to address structural inequities found throughout academia and scholarly publishing. OER have the potential to celebrate research done by marginalized populations in the context of their own communities, to amplify the voices of those who have the knowledge but have been excluded from formal prestige networks, and to engage students as co-creators of learning content that is relevant and respectful of their cultural contexts. Edited by academic librarians with experience advocating across campus, Using Open Educational …

Drivers And Challenges Of Wearable Devices Use: Content Analysis Of Online Users Reviews, Ahmed El Noshokaty, Omar El-Gayar, Abdullah Wahbeh, Mohammad A. Al-Ramahi, Tareq Nasralah

Computer Information Systems Faculty Publications (Archived)

With recent advancements in wearable device technologies, there is still a need to investigate drivers and challenges associated with the use of these devices. Following a content analysis approach, this study leverages recent “found large-scale” data to better understand the drivers and challenges that affect the adoption and use of such devices. Analyzing a total of 16,717 online reviews about wearable devices, the findings emphasized the importance of various functionalities (perceived usefulness), appeal, and a number of device design features as the most prominent drivers, while concerns about quality, credibility, and perceived value as potential challenges to wearable adoption and …

Using Burdens Of Proof To Allocate The Risk Of Error When Assessing Developmental Maturity Of Youthful Offenders, David L. Faigman, Kelsey Geiser

Faculty Scholarship

Behavioral and neuroscientific research provides a relatively clear window into the timing of developmental maturity from adolescence to early adulthood. We know with considerable confidence that, on average, sixteen-year-olds are less developmentally mature than nineteen-year-olds, who are less developmentally mature than twenty-three-year-olds, who are less developmentally mature than twenty-six-year-olds. However, in the context of a given case, the question presented might be whether a particular seventeen-year-old defendant convicted of murder is “developmentally mature enough” that a sentence of life without parole can be constitutionally imposed on him or her. While developmental maturity can be accurately measured in group data, it …

Dynamic 3d In Vitro Bone Metastatic Testbeds For Prostate And Breast Cancer, Haneesh Jasuja

Materials and Nanotechnology

Metastatic prostate cancer spreads preferentially to the bone, causing skeletal complications associated with significant morbidity and a poor prognosis, despite current therapeutic approaches. Increasing evidence suggests the synergistic role of biochemical and biophysical cues in cancer progression at metastases. However, the mechanism underlying the crosstalk between interstitial flow-induced mechanical stimuli and prostate cancer progression in the bone microenvironment remains poorly understood. To this end, we have developed 3D in vitro dynamic models of prostate cancer bone metastasis using perfusion bioreactor and horizontal flow bioreactor to delineate the role of flow-induced shear stress on prostate cancer progression and migration, respectively at …