Digital Commons Network^™

Racism Experiences And Mental Health: An Examination Of Direct, Vicarious, And Appropriated Racism Experiences On Mental Health Symptom Expression, Christina Barnett

Theses and Dissertations

The current study aimed to corroborate existing models of racism-related experiences by creating an explanatory model that operationalized direct, vicarious, and appropriated racism experiences. This study explored whether the factors of direct and vicarious racism experiences influenced mental health outcomes via appropriated racism experiences in a sample of Black women. This association was not present. However, results showed a positive association between vicarious and direct racism experiences, as well as predictive relations between direct and vicarious racism experiences and depression and trauma symptoms. Results, limitations, implications, and recommendations for future research are included.

Keywords: vicarious racism, appropriated racism, direct racism, …

Intergenerational Transmission Of Alexithymia As A Predictor Of Child Posttraumatic Stress Outcomes During Covid-19, Casey Burton

Theses and Dissertations

The objective of this study was to test the role of parent alexithymia in explaining why some children are functioning relatively well during the COVID-19 pandemic while others are experiencing poor mental health. Participants were 88 U.S. children (M_age = 9.94 years; 54.5% female; 59.1% White) and their parents/caregivers (68.2% female; 59.1% White). Two models were tested: a path model in which the association between parent alexithymia symptoms and child COVID-19-related posttraumatic stress symptoms (PTSS) was mediated by child alexithymia symptoms, and a moderator model in which the association between parent alexithymia symptoms and child PTSS was moderated …

Comparison Of The Different Isoforms Of Vitamin E Against Amyloid Beta-Induced Neurodegeneration, Alp Yi̇ği̇t Özdemi̇r, Esi̇n Çeti̇n, Mehmet Ali̇ Onur

Turkish Journal of Biology

Neurodegeneration is the progressive loss of structure or function of neurons. Amyloid beta oligomers and aggregates have been linked to neurodegeneration. While previous studies have suggested that dietary α-tocopherol intake can prevent amyloid beta aggregation and protect the brain against neurotoxicity, other research, however, indicated that tocotrienol forms might be used as an alternate agent against this kind of degeneration. In the presented research, we compared the in vitro protective effects of α-tocopherol and α-tocotrienol. In this context, we formed an in vitro neurodegeneration model with primary isolated neurons and measured α-tocopherol's and α-tocotrienol's protective effects. As a result, α-tocopherol …

A Qualitative Study Of Emergency Department Delirium Prevention Initiatives, Anita Chary, Shan W Liu, Ilianna Santangelo, Kyler M Godwin, Christopher R Carpenter, Aanand D Naik, Maura Kennedy

Faculty, Staff and Students Publications

BACKGROUND: Delirium is a serious but preventable syndrome of acute brain failure. It affects 15% of patients presenting to emergency care and up to half of hospitalized patients. The emergency department (ED) often represents the entry point for hospital care for older adults and as such is an important site for delirium prevention.

OBJECTIVE: We sought to characterize delirium prevention initiatives in EDs in the United States and Canada.

METHODS: We conducted qualitative interviews with 16 ED administrators representing 14 EDs with delirium prevention initiatives. We used a combined deductive-inductive approach to code responses about involved staff, target patient population, …

Racial/Ethnic Variations In Alcohol And Cigarette Use By Pregnancy Status Among 20- To 44-Year-Old Women, Nhanes 2001–2018, Jacqueline M Hirth, Catherine Valadez, Sandra Gonzalez, Alicia Kowalchuk, Judith A Gutierrez, Roger Zoorob

Faculty, Staff and Students Publications

OBJECTIVES: This study examines alcohol consumption and smoking behaviors by pregnancy status and race/ethnicity in order to inform improved interventions designed to assist women of all races to avoid alcohol and tobacco use during pregnancy for their health and to prevent potential fetal exposure.

METHODS: This retrospective secondary data analysis utilized nationally representative National Health and Nutrition Examination Survey data between 2001 and 2018. Smoking and alcohol use were evaluated by race/ethnicity and pregnancy risk. Sexual behavior, reproductive health, and prescription drug use determined pregnancy risk, categorized as low pregnancy risk, at risk of becoming pregnant, and pregnant. Binary and …

A Survey On Self-Medication For The Prevention Or Treatment Of Covid-19 And Distrust In Healthcare Of Veterans In A Primary Care Setting In The United States, Eva Amenta, Larissa Grigoryan, Laura Dillon, Casey Hines-Munson, John Van, Barbara Trautner

Faculty, Staff and Students Publications

BACKGROUND: The SARS-CoV-2 (COVID-19) pandemic brought the public overwhelming and conflicting information. Rates of trust in healthcare professionals have been declining among laypersons over the past five decades. In this setting, we sought to evaluate the use of medications, both with or without a prescription, to prevent and treat SARS-CoV-2 as well as trust in healthcare among patients in a primary care clinic.

DESIGN: We surveyed 150 veterans in primary care clinic waiting rooms at a large southwestern tertiary care Veterans Affairs hospital. This survey was performed in March-November 2021.

METHODS: The survey asked about respondents' demographics, use of medications, …

Multiplex Hextuple Luciferase Assaying, Alejandro Sarrion-Perdigones, Yezabel Gonzalez, Lyra Chang, Tatiana Gallego-Flores, Damian W Young, Koen J T Venken

Faculty, Staff and Students Publications

We recently expanded the commonly used dual luciferase assaying method toward multiplex hextuple luciferase assaying, allowing monitoring the activity of five experimental pathways against one control at the same time. In doing so, while our expanded assay utilizes a total of six orthogonal luciferases instead of two, this assay, conveniently, still utilizes the well-established reagents and principles of the widely used dual luciferase assay. Three quenchable D-luciferin-consuming luciferases are measured after addition of D-Luciferin substrate, followed by quenching of their bioluminescence (BL) and the measurement of three coelenterazine (CTZ)-consuming luciferases after addition of CTZ substrate, all in the same vessel. …

Adult Memory T Cell Responses To The Respiratory Syncytial Virus Fusion Protein During A Single Rsv Season (2018-2019), Brittani N Blunck, Laura S Angelo, David Henke, Vasanthi Avadhanula, Matthew Cusick, Laura Ferlic-Stark, Lynn Zechiedrich, Brian E Gilbert, Pedro A Piedra

Faculty, Staff and Students Publications

Respiratory Syncytial Virus (RSV) is ubiquitous and re-infection with both subtypes (RSV/A and RSV/B) is common. The fusion (F) protein of RSV is antigenically conserved, induces neutralizing antibodies, and is a primary target of vaccine development. Insight into the breadth and durability of RSV-specific adaptive immune response, particularly to the F protein, may shed light on susceptibility to re-infection. We prospectively enrolled healthy adult subjects (n = 19) and collected serum and peripheral blood mononuclear cells (PBMCs) during the 2018–2019 RSV season. Previously, we described their RSV-specific antibody responses and identified three distinct antibody kinetic profiles associated with infection …

Exercise-Induced Myokines Downregulates The Ace2 Level In Bronchial Epithelial Cells: Implications For Sars-Cov-2 Prevention, Vaishali Bhardwaj, Mart Dela Cruz, Deepika Subramanyam, Rohit Kumar, Sandeep Markan, Beth Parker, Hemant K Roy

Faculty, Staff and Students Publications

BACKGROUND: The Covid-19 pandemic has emerged as the leading public health challenge of our time (20th century). While vaccinations have finally blunted the death rate, concern has remained about more virulent forms highlighting the need for alternative approaches. Epidemiological studies indicate that physical activity has been shown to decrease the risk of infection of some respiratory viruses. Part of the salutary effects of exercise is believed to be through the elaboration of cytokines by contracting skeletal muscles (termed myokines). The objective of this study was to investigate whether exercise-induced myokines would mitigate the SARS-CoV-2 infectivity of the bronchial epithelium through …

How Do Digital Lives Affect Resident Mental Health In The Digital Era? Empirical Evidence Based On Chinese General Social Survey, Yan Chen, Mengyang Wei, Jaime Ortiz

Faculty, Staff and Students Publications

Having good mental health means we are better able to connect, function, cope and thrive. The widespread application of digital technology in daily life provides new ways and promising tools for residents to maintain their mental health. Given the importance of mental health for everyone, and the fact that mental health problems are prevalent worldwide, this study discusses how digital lives affects the mental health of residents. The results suggest that digital lives are significantly and positively associated with mental health. Mechanisms analysis identifies personal perceptions (self-rated physical exercise and subjective wellbeing) as the important paths for digital lives to …

Culturally Relevant Coping Strategies Within Bicultural Latine College Students In The Face Of Anti-Immigrant Sentiment And Policy, Cindy M. Hernandez

Theses and Dissertations

Despite their protective potential against anti-immigrant sentiment and policy, the connections between bicultural identity development and culturally relevant coping among temporarily documented Latinx college students remain unstudied. Therefore, this study (a) describes culturally relevant coping strategies used by bicultural Latinx college students, (b) examines the role cultural identity plays in bicultural Latinx college students’ coping strategies, and (c) illuminates the role institutional level systems play in liminally-documented college students’ coping with anti-immigrant sentiment and policy. Participants in this study included 16 Latine college students (M_age = 21.19, SD = 3.21) with DACA (n = 14) or TPS (n = …

Less Water, More Holy: Tools For Sustainable Ablution, Faheem Khan

Theses and Dissertations

Prayer is an important part of life for many people, whether it takes the form of meditation or talking to God. Muslims pray five times a day, and before each prayer, they first clean themselves by performing ritual ablution (wudu). The eight-step purification process of wudu cleanses the body from head to toe. The Hadiths of Sahih al-Bukhari and Sahih Muslim tell us the Prophet Muhammad ﷺ needed just one mudd of water (650ml) to complete wudu, but most people consume many times that amount—four-to-seven liters is more common today.

To visualize and better understand the nature …

Adaptations In Orthodontics For Current And Future Covid-19 Best Practices, Jordan Lamb

Theses and Dissertations

Purpose: To determine what adaptations orthodontists made in their practices during the COVID-19 pandemic in response to safety recommendations and to determine which of these adaptations orthodontists plan to continue to implement after resolution of the COVID-19 pandemic.

Methods: An original 34-question survey was sent by mail to a randomized and geographically proportionate selection of actively practicing orthodontic specialists (N = 1000). Questions asked orthodontists about the changes they made during the pandemic in four overarching categories (infection control, social distancing, appliance use, and tele-orthodontics) and whether they anticipated keeping those changes post-pandemic. The data were compared between categorical responses …

Roots And Webs And Nets And Branches And Bulletin Boards And Banners And Newsletters And Mutual Aid Text Threads And Kin And Caretakers And Porches And Poems Of Today And Spaces Of Survival, Lukaza Branfman-Verissimo

Theses and Dissertations

As I welcome Richmond, VA into my family, I find myself needing to make roots and webs and nets and branches that ground me, that place myself as a Black, queer, mixed race, artist, activist, educator, storyteller, and cultural worker in this city. I am called to the streets before I am called to my studio. I question what it means to be a part of an institution that is slowly eating this city up. I become a story collector. I need to know where I am and whose land I now call home.

Exploring Digital Equity Through Parent Perceptions Of Students’ Use Of 1:1 Devices: A Mixed Methods Approach, Joy Washington

Theses and Dissertations

Over the last two decades, 1:1 initiatives, in which each child in a school building is provided a school-issued device, have increased dramatically around the world. However, the outcomes of such programs are not always clear and studies regarding 1:1 one programs have found mixed results. It is important to ensure that1:1 initiatives are equitable and do not perpetuate the digital divide. Many studies exist that examine use of 1:1 devices in schools from a teacher or student perspective. However, only a few studies examine the experience of 1:1 initiatives from a parent perspective and also focus on equity. The …

Graduate School's Transformative Awakening: An Arts-Based Autoethnography, Roxanne L. Brown

Theses and Dissertations

This is an autoethnographic journey of a 30-year veteran art teacher through graduate school during the 2016 presidential campaign, election, presidency, #MeToo movement, a global pandemic, Black Lives Matter (BLM), virtual teaching and grading during a pandemic. My narrative includes an account of my transformative academic, social, and personal experiences and how they have informed my teaching practice. They include a collection of visual representations I created during my graduate school journey.

The Value Of Educating Teachers, Coaches, And Athletic Trainers On The Management Of Dental Trauma., Laura Satoski

Theses and Dissertations

Purpose: The aim of this study is to investigate the baseline knowledge and assess the benefit of educating teachers, coaches, and athletic trainers about the management of sports-related dental injuries.

Methods: Teachers, coaches, and athletic trainers working in youth sports activities across the city of Richmond and the Greater Richmond Region were recruited via email. Participants answered a pre-seminar survey to evaluate their baseline knowledge and determine whether they experienced dental trauma with their athletes previously. The survey also indicated whether they participated in a public or private sports facility. The participants watched a pre-recorded virtual seminar educating them on …

“What Have We Got To Celebrate?”: Native American Contestation To Commemoration During The Late 20th Century, Jennifer C. Tennison

Theses and Dissertations

This thesis examines how Indigenous groups in the United States have contested mainstream historical narratives of America’s founding during major commemorative events in the late twentieth century. To analyze this, I have examined two major national commemorative events during which Native Americans spearheaded a marked shift in the popular interpretation of national origins. The first event I analyze is the 1976 Bicentennial of the American Revolution; the second event is the 1992 Columbus Quincentenary. Native Americans contested the ways that the federal planning bodies for both events represented the history of the nation’s founding. How could they be called on …

The Civil Right To Belong: A Case Study On Immigrant Integration Of Muslim Students In Educational Institutions, Mamoona H. Siddiqui

Theses and Dissertations

Constitutional equal protection values serve as social integration policies for new Americans and generations that follow. They promise equal opportunity, fair treatment, protection from unlawful discrimination, and freedom to preserve cultural identities in their new communities. However, in times of national security crises and political polarization, the disjuncture in the way equal protection doctrines have been historically implemented often reflect deep-rooted inequities that impact underrepresented communities. American Muslims are one such community in which members have experienced anti-Muslim and anti-immigrant sentiment particularly after 9/11 and political polarization on immigration and civil rights policies. The study explores the equal protection doctrine …

Childhood Reliquary De Una Catracha/Mexi Entre Nopales, Juliana Bustillo

Theses and Dissertations

Childhood Reliquary De Una CatrachaMexi Entre Nopales is a multisensory based installation consisting of three large and six medium scale mixed media paintings with performance. It is informed by my upbringing in Boyle Heights in the projects during the 90s, followed by East LA in the mid 2000s. It is the reliquary for my discomfort in institutional spaces and why I have found comfort in dystopian-like installations. This is the landscape in which I exist, regardless of where I am now. It is where I place my work. It is the context in which I celebrate the powerful delicacy of …

Once Upon A Time/There Was A Story That Began: Novelty, Endings, And Chronotope In John Barth’S The Tidewater Tales, Zachary K. Gibson

Theses and Dissertations

This thesis examines the use of frame tales, genre blending, multi-voiced narration, and circular structure in John Barth’s 1987 novel, The Tidewater Tales. It tracks the isomorphy of Barth’s general aesthetic project, set forth in his essays, “The Literature of Exhaustion,” “The Literature of Replenishment,” and “Very Like an Elephant: Reality Versus Realism,” onto the theoretical aesthetics of Russian philosopher Mikhail Bakhtin. Both Barth and Bakhtin praise the novel its omnivorous capability to accommodate, and juxtaposes conflicting genres against one another; they each see the novelist as an “arranger” or “orchestrator,” who reassembles pre-existing forms to make them …

Metal Nanoparticle Synthesis Via Laser-Induced Photochemical Reduction Of Metal Salts, Laysa M. Frias Batista

Theses and Dissertations

Significant attention has been focused on metal nanoparticles (MNPs) due to their unique optical, catalytic, and electronic properties. In the last two decades, laser synthesis techniques have emerged as versatile routes to MNPs that enable control over particle size, shape, and surface chemistry without the use of chemical reducing agents or surface-blocking capping ligands. A method gaining increasing attention is the direct laser-driven reduction of metal salts, called Laser Reduction in Liquid (LRL). LRL typically involves the use of intense laser pulses of picosecond or femtosecond duration to ionize and dissociate solvent molecules, generating plasmas with reactive chemical species such …

Snapshots Of A Fictional Past: Photographic Nostalgia In The Early 20th Century Art Novel., Harry A. Jones Iv

Theses and Dissertations

In this dissertation I argue that the proliferation of a mass codependent relationship with nostalgia in the twentieth century shares a parallel history with the widespread adoption of the reproducible image being used by collective audiences as a supplement for natural memory, or what Proust names “voluntary memory.” This conflict between nostalgia-hungry consumers and artists inspired groups such as Alfred Stieglitz’s Photo-Secessionists and artistically minded authors like Henry James, who employed increasingly complex photographic and literary practices to resist the images’ tendency to debase the aesthetic quality of their own work. Authors such as Marcel Proust and William Faulkner used …

A Novel Approach To Reducing Adiposity Among Young Men, Jean M. Reading

Theses and Dissertations

Background

Lifestyle intervention is the first line treatment for obesity. Yet, young men are underrepresented in lifestyle interventions, which is posited to be the result of unmet needs and overall low concern for weight management. The aims of this dissertation are to:

Papers 1 and 2: Test the preliminary efficacy, feasibility, and acceptability of a self-guided lifestyle intervention for young men.

Paper 3: Explore the behavioral and physiological factors associated with changes in adiposity among young men and women enrolled in a more intensive lifestyle intervention.

Results

Papers 1 and 2: The self-guided intervention produced modest weight …

Novel Microfabricated Systems To Elucidate The Role Of Anisotropic Stiffness In The Tumor Microenvironment, Jiten Narang

Theses and Dissertations

Cancer is the second leading cause of death in women and late stage (metastatic) cancers have abysmal survival rates compared to early stage regional cases (27% vs 86%). As a tumor grows, the surrounding extracellular matrix (ECM) is reorganized into a dense, collagen rich matrix. The new matrix of aligned collagen fibers provides unique mechanical cues such as anisotropic stiffness and contact guidance. Matrix turnover also constricts local vasculature and restricts delivery of key nutrients and signaling molecules to malignant cells to outside the tumor creating a chemotactic gradient from outside to inside. In this work, we developed a novel …

Synthesis And Modeling Of Manganese Ferrite Nanoparticles For Magnetic Hyperthermia Applications, Margaret E. Thornton

Theses and Dissertations

Biologically targeted magnetic hyperthermia (MH) is a promising cancer therapeutic that is both non-invasive and has the potential to serve as a single-modality cancer treatment. MH operates through the elevation of temperatures between 40-43 °C to induce apoptosis in malignant tumor cells, while the small size of the magnetic nanoparticles preserves the healthy surrounding tissue. At present, MH is limited by low heating efficiency and heterogenous outcomes, and treatment requires direct-injection of the nanoparticles, excluding deep-tissue and metastatic tumors from the therapy. The most popular candidates for MH are the spinel ferrites iron oxide and manganese iron oxide (MFO). These …

Progress Towards Next Generation Modulators Of Ctbp's Oncogenic Effects, Jacqueline L. West

Theses and Dissertations

Human C-terminal binding proteins (CtBP1 and CtBP2) are transcriptional coregulators of multiple genes in the human genome, including tumor suppressor genes (e.g., Bik, PTEN, BRCA1, and E-cadherin) as well as oncogenes (e.g. MDR1 and Tiam1). Both homologues of CtBP are overexpressed in many types of cancer, including breast cancer (92%), ovarian cancer (83%), colorectal cancer (64%), hepatocellular carcinoma (60%), gastric cancer, prostate cancer, and pancreatic adenocarcinoma. Further, expression levels of CtBP correlate with worse prognostic outcomes and more aggressive tumor features because it promotes proliferation, epithelial-mesenchymal transition, and cancer stem cell self-renewal activity.

Our laboratory has identified a lead inhibitor …

Estimating The Statistics Of Operational Loss Through The Analyzation Of A Time Series, Maurice L. Brown

Theses and Dissertations

In the world of finance, appropriately understanding risk is key to success or failure because it is a fundamental driver for institutional behavior. Here we focus on risk as it relates to the operations of financial institutions, namely operational risk. Quantifying operational risk begins with data in the form of a time series of realized losses, which can occur for a number of reasons, can vary over different time intervals, and can pose a challenge that is exacerbated by having to account for both frequency and severity of losses. We introduce a stochastic point process model for the frequency distribution …

Puddlefist, Dylan Ahern

Theses and Dissertations

This written thesis focuses on my MFA thesis exhibition, Puddlefist. It begins with an introduction to both the artworks and my artistic approach, then discusses the text Transcendental Black Metal by Hunter Hunt-Hendrix, which serves as a larger reference point for the work. The latter part of this written thesis is a narrative influenced by the convergence of the sculptures that comprise the exhibition. I consider it a form of endurance writing that exercises motifs of noise, mantra, and monotony. In the section entitled Puc and Yellow, NPC (non-playable character) dialogue from the video game Fallout: New Vegas is transcribed …

Eadah: Tools For Celebrating Qatari Wellness Rituals, Abdulrahman Al Muftah

Theses and Dissertations

Friday prayer is an essential congregational practice in Muslim communities. To prepare for Friday prayer, worshippers groom and cleanse themselves ahead of time, according to Islamic ablution rituals, and dress in their best attire.

Eadah is a collection of contemporary tools designed to facilitate the pre-prayer cleansing ritual, inspired by traditional Qatari remedies and wellness practices. The tools reflect three balanced considerations: touch, meditative making, and cultural preservation. They are used to prepare natural ingredients through mindful making that produce remedies with stimulating scents and sensations through touch. An emphasis on cultural preservation differentiates Eadah from other tools offered by …