Digital Commons Network^™

Exercise In Advanced Prostate Cancer Elevates Myokine Levels And Suppresses In-Vitro Cell Growth, Jin Soo Kim, Dennis R. Taaffe, Daniel A. Galvão, Nicolas H. Hart, Elin Gray, Charles J. Ryan, Stacey A. Kenfield, Fred Saad, Robert U. Newton

Research outputs 2022 to 2026

Background:

Altering the systemic milieu through exercise has been proposed as a potential mechanism underlying exercise-driven tumour suppression. It is not yet known whether men with advanced prostate cancer can elicit such adaptations following a program of exercise. The purpose is to examine myokine levels of serum acquired from metastatic castrate-resistant prostate cancer (mCRPC) patients recruited to the INTERVAL-GAP4 trial before and after 6 months of exercise and its tumour-suppressive effect.

Methods:

Twenty-five men with mCRPC (age = 74.7 ± 7.1 yrs) were randomised to supervised multimodal (aerobic and resistance) exercise (EX) or self-directed exercise control group (CON). Body composition …

Overview Of Aboriginal And Torres Strait Islander Health Status, 2021, Australian Indigenous Healthinfonet

Research outputs 2022 to 2026

The main purpose of the Overview of Aboriginal and Torres Strait Islander health status (Overview) is to provide a comprehensive summary of the most recent indicators of the health and current health status of Australia’s Aboriginal and Torres Strait Islander people. The Overview has been prepared by HealthInfoNet staff as part of our contribution to supporting those who work in the Aboriginal and Torres Strait Islander health sector. The Overview is a key indicator of the HealthInfoNet’s commitment to authentic and engaged knowledge development and exchange. The initial sections of this Overview provide information about the context of Aboriginal and …

The Role Of Microstructure On High-Temperature Oxidation Behavior Of Hafnium Carbide, Jonathan A. Scott, Xiaoqing He, David W. Lipke

Materials Science and Engineering Faculty Research & Creative Works

Microstructure development of the products formed upon oxidation of hafnium carbide (HfCx, x = 0.65, 0.81, or 0.94) at 1300°C and 0.8 mbar oxygen pressure was investigated using Raman spectroscopy, X-ray diffraction, electron microscopy, and electron energy-loss spectroscopy. For all specimens a multilayered oxide scale was observed featuring an outermost porous hafnia layer and an interlayer adjacent to the parent carbide containing hafnia interspersed with carbon. The outermost hafnia features coarse pores presumably formed during initial stages of oxidation to allow rapidly evolving gaseous products to escape from the oxidation front. As the oxidation scale thickens, diffusional resistance results in …

Re-Crosslinking Particle Gel For Co2 Compliance Control And Co2 Filtration Blocking, Yifu Long, Baojun Bai, Thomas P. Schuman

Patents

The present invention generally relates to the composition of particle gels for CO2 - EOR and CO2 storage . More particularly , CO2 resistant particle gels are provided that can re - crosslink at subterranean conditions . These particle gels can be deployed to improve the conformance of CO , flooding , CO , huff - puff , or Water - Alternative - Gas ( WAG ) . The applications may also involve CO2 storage , such as the blocking of CO2 leakage and similar CO2 processing .

Fiber Assisted Re-Cross-Linkable Polymer Gel And Preformed Particle Gels For Fluid Loss And Conformance Control, Baojun Bai, Ze Wang, Zhe Sun, Jingyang Pu, Thomas P. Schuman

Patents

Described herein are compositions useful for controlling fluid flow, for example in a target zone of a subterranean environment, and methods of forming and using the same. The composition generally comprises a quantity of fibers and a quantity of swellable particles, which may be dispersed in a carrier fluid. The composition may be synthesized in the form of a bulk gel or may be gelatinated during use. The fibers in the compositions provide improved performance as compared to prior PPG and RPPG particle containing compositions. Specifically, the compositions reinforce the re-cross-linked/re-associated hydrogel plug in underground features and support proper rehydration …

Fuel Cell Having Corrugated Membrane Electrode Assembly, Jonghyun Park

Patents

An electrochemical reaction cell comprising an anode electrode, a cathode electrode, and a membrane electrode assembly (MEA). The MEA is positioned between the anode electrode and the cathode electrode. The anode electrode, the cathode electrode, and the MEA each have a corrugated shape and are contained within a recess of a housing.

3d-Printed Gelatin-Alginate Hydrogel Dressings For Burn Wound Healing: A Comprehensive Study, Fateme Fayyazbakhsh, Michael J. Khayat, Ming-Chuan Leu

Mechanical and Aerospace Engineering Faculty Research & Creative Works

Burn Wound Treatment is Still a Clinical Challenge Due to the Severity of Tissue Damage and Dehydration. among Various Wound Dressings, Hydrogel Materials Have Gained Significant Attention for Burn Wound Treatment in Clinical Practice Due to their Soothing and Moisturizing Activity. in This Study, 3D-Printed Dressings Were Fabricated using Clinically Relevant Hydrogels for Deep Partial-Thickness Burn (PTB) Wounds. Different Ratios of Gelatin and Alginate Mixture Were 3D-Printed and Examined in Terms of Rheological Behavior, Shear Thinning Behavior, Mechanical Properties, Degradation Rate, and Hydration Activity to Tune the Hydrogel Composition for Best Functionality. the Cell-Laden Dressings Were Bioprinted to Evaluate the …

A Bim+Blockchain Approach To Ensure Transparency In The Strategic Housing Development Planning System, Carlo Orani, Malachy Mathews Dr

Conference papers

The introduction of the fast-tracking housing regulations in Ireland has modified the dynamics in which democratic participation is deployed in planning decisions. The resulting planning process has favoured inequality phenomena and has strengthened the position of construction lobbies in large-scale developments. This paper enforces citizen engagement in the Strategic Housing Development (SHD) framework using Building Information Modelling (BIM) and blockchain technologies to build digital trust. Digital tools have enormous potential to deliver more transparent planning by establishing proven accountability for building permissions and promoting trusted interactions between citizens and local administrations. This study first describes all the reasoning underpinning the …

Patient Generated Health Data And Electronic Health Record Integration, Governance And Socio-Technical Issues: A Narrative Review, Abdullahi Abubakar Kawu, Lucy Hederman, Julie Doyle, Dympna O'Sullivan

Articles

Patients’ health records have the potential to include patient generated health data (PGHD), which can aid in the provision of personalized care. Access to these data can allow healthcare professionals to receive additional information that will assist in decision-making and the provision of additional support. Given the diverse sources of PGHD, this review aims to provide evidence on PGHD integration with electronic health records (EHR), models and standards for PGHD exchange with EHR, and PGHD-EHR policy design and development. The review also addresses governance and socio-technical considerations in PGHD management. Databases used for the review include PubMed, Scopus, ScienceDirect, IEEE …

Investigating How Speech And Animation Realism Influence The Perceived Personality Of Virtual Characters And Agents, Sean A. Thomas, Ylva Ferstl, Rachel Mcdonnell, Cathy Ennis

Articles

The portrayed personality of virtual characters and agents is understood to influence how we perceive and engage with digital applications. Understanding how the features of speech and animation drive portrayed personality allows us to intentionally design characters to be more personalized and engaging. In this study, we use performance capture data of unscripted conversations from a variety of actors to explore the perceptual outcomes associated with the modalities of speech and motion. Specifically, we contrast full performance-driven characters to those portrayed by generated gestures and synthesized speech, analysing how the features of each influence portrayed personality according to the Big …

The Trouble With Harman And Lorandos’S Attempted Refutation Of The Meier Et Al. Family Court Study, Joan S. Meier, Sean Dickson, Chris S. O'Sullivan, Leora N. Rosen

GW Law Faculty Publications & Other Works

Harman and Lorandos assert that they have produced a study analyzing custody cases involving alienation allegations, which “disconfirms” the findings from our study of family court out- comes in cases involving abuse and alienation. In addition to pointing out the authors’ misrepresentation and mis-reporting of some of their findings, this Response details a series of profound flaws in their study’s design, dataset construction and variable coding, interpretations and analytic approach, as well as a series of statistical errors. The statistical analyses demonstrate that Harman and Lorandos’s five findings of a gender bias in favor of fathers are not supported by …

Firearms And Initial Aggressors, Cynthia Lee

GW Law Faculty Publications & Other Works

Under the initial aggressor doctrine, an “initial aggressor” loses the right to claim self-defense. Until recently, judges, legal scholars, and others have paid relatively little attention to this doctrinal limitation on the defense of self-defense. Two high-profile criminal trials in 2021 put the initial aggressor doctrine front and center of the national conversation on issues concerning self-defense and racial justice. One involved Kyle Rittenhouse, the 17-year-old teenager who brought an AR-15 style rifle to Kenosha, Wisconsin during the third night of racial protests in August 2020, and ended up shooting three men, killing two and injuring the third. The other …

The Common Sense Of A Wealth Tax: Thomas Paine & Taxation As Freedom From Aristocracy, Jeremy Bearer-Friend, Vanessa Williamson

GW Law Faculty Publications & Other Works

Thomas Paine’s writing helped spur the American colonies to independence and ensure that the new nation would be a republic, not a monarchy. In light of the renewed interest in wealth taxes, this article provides a close examination of Thomas Paine’s wealth tax proposal in the second volume of The Rights of Man. Unlike Paine’s proposal to tax inheritances, his 1792 proposal to tax wealth on an annual basis is often overlooked. The article identifies Paine’s various design specifications, provides original estimates of the impact of Paine’s wealth tax proposal within his own time period and as applied to billionaires …

Regulating Big Tech: Lessons From The Ftc’S Do Not Call Rule, William E. Kovacic, David A. Hyman

GW Law Faculty Publications & Other Works

Big Tech (Amazon, Apple, Facebook, and Google) is under regulatory assault. Cases have been brought against each of these companies in multiple countries around the world, but there is an emerging consensus that more needs to be done – most likely in the form of ex ante regulation that prescribes rules of conduct for dominant information platforms. The European Union and the United Kingdom are well on the way to establishing such frameworks, and the United States appears poised to undertake similar measures in the coming years. Most of the debate has focused on the case for ex ante regulation …

Medicare For All, Health Justice, And The Laboratories Of Democracy, Elenore Wade

GW Law Faculty Publications & Other Works

A growing majority of Americans support the implementation of a national single-payer healthcare program, also known as Medicare for All, which would shift payments for healthcare services to a single public payer and provide care based on need rather than ability to pay. However, legislators, scholars, and advocates have suggested state governments rather than the federal government should take the lead by implementing state-based single-payer programs. Dozens of single-payer proposals have been introduced in state legislatures across the country, and proposed legislation in Congress would remove the federal roadblocks to state-based single-payer’s implementation. Proponents of state-based single-payer rely on the …

An Overview Of Privacy Law In 2022, Daniel J. Solove, Paul M. Schwartz

GW Law Faculty Publications & Other Works

Chapter 1 of PRIVACY LAW FUNDAMENTALS (6th edition, IAPP 2022) provides an overview of information privacy law circa 2022. The chapter summarizes the common themes in privacy laws and discusses the various types of laws (federal, constitutional, state, international). It contains a list and brief summary of the most significant U.S. federal privacy laws. The heart of the chapter is an historical timeline of major developments in the law of privacy and data security, including key cases, enactments of laws, major regulatory developments, influential publications, and other significant events. The chapter also contains a curated list of important treatises and …

Unsexing Breastfeeding, Naomi Schoenbaum

GW Law Faculty Publications & Other Works

For half a century, constitutional sex equality doctrine has been combating harmful sex stereotypes by invalidating laws that treat women as caregivers and men as breadwinners. Yet decades after the constitutional sex equality revolution unsexed parenting roles, one area of parenting has escaped this doctrine’s exacting gaze: breastfeeding. Beginning in the 1990s in the wake of public health efforts to promote breastfeeding, a raft of laws were enacted, from insurance coverage mandates under the Affordable Care Act to workplace accommodations under the Fair Labor Standards Act, that provide substantial breastfeeding protections and benefits, but only to women. Although the sexed …

Selective Judicial Activism In The Roberts Court, Alan B. Morrison

GW Law Faculty Publications & Other Works

In Dobbs v. Jackson Women’s Health Organization, Justice Samuel Alito offers two main reasons why there is no Due Process right to an abortion in the Constitution, and hence why Roe v. Wade should be overturned: abortion is not mentioned in the text, and decisions about whether abortions should be permitted and, if so, under what conditions, are properly the province of the elected representatives and not federal judges. In this essay I show that, in many of the most significant cases decided by the Roberts Court, the Court has disregarded both of those reasons, and engaged in the kind …

Between A Rock And A Hard Place? Ict Companies, Armed Conflict, And International Law, Arturo J. Carrillo

GW Law Faculty Publications & Other Works

What is an ICT company to do when operating in the midst of international armed conflict like the one raging in Ukraine? How should tech company executives respond to urgent government demands – often conflicting -- to propagate or censor online content arising in the context of war, including disinformation? And what of their demands to access the personal data or communications of users, ostensibly to safeguard security but nonetheless presenting the potential for abuse? Governments make difficult demands of ICT companies by seeking to impose heavy restrictions on the free flow of information and data privacy via the latter’s …

Overcoming Corruption And War -- Lessons From Ukraine's Prozorro Procurement System, Christopher R. Yukins, Steven Kelman

GW Law Faculty Publications & Other Works

After the 2014 uprising against widespread corruption under former Ukrainian President Victor Yanukovych, a group of civic activists and data experts decided to overhaul government procurement. Their efforts produced an open-source e-procurement system, ProZorro (“transparency” in Ukrainian), and a community of citizens and government buyers, Dozorro (“watchdog” in Ukrainian), that analyzes contracting data, flags high-risk deals and irregularities, and reports them to government authorities. Created with the help of the European Bank for Reconstruction and Development and the U.S. Agency for International Development, ProZorro has helped Ukraine save almost $6 billion in public funds since October 2017, according to the …

No Man Is An Island In Defense Procurement: Developments In Eu Defense Procurement Regulation And Its Implications For The U.S., Luke R.A. Butler, Michael Bowsher, Christopher R. Yukins

GW Law Faculty Publications & Other Works

The Russian invasion of Ukraine and the United Kingdom’s exit from the European Union have focused minds on the EU’s role as a defense actor. In the context of defense procurement, this includes whether the EU should itself co-fund cooperative programmes with Member States (through the European Defense Fund, for example, and Permanent Structured Cooperation (PESCO) initiatives among Member States), what can be commonly procured (and what cannot, e.g., due to prohibitions against offsets), and how (for example, under the competing constraints of Article 346 of the Treaty on Functioning of the European Union (TFEU) and the 2009 European Defense …

Integral Equation Formulation For Planar Plasmonic Structures With Finite Thickness In Layered Media, Esraa M. Mahdy, Alaa Abdelmageed, Ezzeldin A Soliman

Faculty Journal Articles

A detailed Volume Integral Equation (VIE) formulation for planar plasmonic nano structures with finite thickness in flat multi-layers medium is presented. The boundary condition along the localized metallic objects is expressed in terms of the unknown polarization current flowing through these objects in the form of an integral equation, which is solved using the Method of Moments (MoM). The Green's functions associated with a layered medium of practical importance are expressed in the spectral domain. The corresponding spatial domain Green's functions are obtained using the Discrete Complex Images Method (DCIM). Special treatment for the spectral function's asymptote at high spectral …

Establishing And Characterizing Patient-Derived Breast Cancer Cell Lines, Farid Solaymani Mohammadi

Biological Sciences

Commercial cancer cell lines have long been extensively used as an important platform to study cancer. They have contributed to a plethora of discoveries in the field of cancer research. However, there are limitations with using these cell lines, such as induced mutations over the long-term in vitro culture. These mutations cause incorrect exhibition of the in vivo characteristics of the cancer cells. Here, we focused on establishing Patient-derived breast cancer cell lines and attempted to characterize them in terms of several biomarkers that are shown to be overexpressed in breast cancer cells. Patient-derived breast cancer cell lines are more …

Eye Movement And Pupil Measures: A Review, Bhanuka Mahanama, Yasith Jayawardana, Sundararaman Rengarajan, Gavindya Jayawardena, Leanne Chukoskie, Joseph Snider, Sampath Jayarathna

Computer Science Faculty Publications

Our subjective visual experiences involve complex interaction between our eyes, our brain, and the surrounding world. It gives us the sense of sight, color, stereopsis, distance, pattern recognition, motor coordination, and more. The increasing ubiquity of gaze-aware technology brings with it the ability to track gaze and pupil measures with varying degrees of fidelity. With this in mind, a review that considers the various gaze measures becomes increasingly relevant, especially considering our ability to make sense of these signals given different spatio-temporal sampling capacities. In this paper, we selectively review prior work on eye movements and pupil measures. We first …

Camouflaged Poisoning Attack On Graph Neural Networks, Chao Jiang, Yi He, Richard Chapman, Hongyi Wu

Computer Science Faculty Publications

Graph neural networks (GNNs) have enabled the automation of many web applications that entail node classification on graphs, such as scam detection in social media and event prediction in service networks. Nevertheless, recent studies revealed that the GNNs are vulnerable to adversarial attacks, where feeding GNNs with poisoned data at training time can lead them to yield catastrophically devastative test accuracy. This finding heats up the frontier of attacks and defenses against GNNs. However, the prior studies mainly posit that the adversaries can enjoy free access to manipulate the original graph, while obtaining such access could be too costly in …

Research And Graduate Studies Annual Report, 2022, Office Of Research And Graduate Studies, Illinois State University

Research and Graduate Studies Annual Report

No abstract provided.

Assessing And Meeting The Mental Health Needs Of Student Athletes - A Case Study Of The University Of Northern Iowa, Samantha Bennett

Honors Program Theses

It is my hope with this work to shed light on these grave issues facing our student-athletes at UNI, and to more greatly inform community members about the real experiences of this population. Readers should come away with an understanding of why greater action is necessary to help our student-athletes and remedy the disparities our campus is seeing in terms of mental health resource need and acquisition.

For stakeholders and institutional leaders at UNI, I hope this paper may provide a helpful and informed
framework for responding to the issues being presented by our athletics community.

Blough Dairy Farm Comprehensive Safety & Training Manual, Riley Elaine Elenz

Honors Program Theses

No abstract provided.

Social Media Recruitment And Online Propaganda By Extremist Groups, Megan Marie Robinson

Honors Program Theses

As billions of people turn to their technologically elite phones and laptops for immediate information, online groups have learned how to take advantage of social media patterns and isolate people into a specific belief or carefully tailored platforms that eliminate opposing ideas. Extremist groups’ online presence have been studied as individual dilemmas, rather than being studied for patterns to combat the rapidly increasing radicalization of people who had no claim to these beliefs before social media. This study will contrast the online presence of the Islamic State of Iraq and Syria (ISIS) and the January 6th insurrectionists in terms of …

Using Color With Care: An Exploration Of The Application Of Psychological Color Theory Within Language Classrooms, Mackenzie Wisneski

Honors Program Theses

This study is a qualitative analysis of the current use(s) of affective-based color theory for social-emotional and academic-related assistance within language classrooms. Current and past literature support the important and effective nature of a learner’s environment in relation to information acquisition and retention (Krashen, 1982; Maslow, 1970b; Perry, 2006). This research is significant within the language teaching field as it stands to summarize the external challenges that emergent bilingual students are facing as well as contextualize their learning environment with respect to the use of visual cues to promote both the students’ social-emotional wellbeing and academic success. Data was collected …