Digital Commons Network^™

Preservice Teachers, Antiracism, And Racial Literacy: Exploring Current Preservice Teachers' Definitions And Perceptions Of Racism And Antiracism Within Teacher Education, Olivia Gabrielle Terrones

Honors Program Theses

In teacher preparation programs across the country, racial discourse has grown in relevance and become an increasingly common aspect of teacher preparation programs. This study will explore the perceptions of preservice teachers on topics of race. Through a research survey of 120 current University of Northern Iowa preservice teachers, this study will explore and analyze how current UNI preservice teachers view and define racism and antiracism, where the participants place themselves on a racial literacy continuum, and how they value antiracist racial literacy in their future careers as teachers. Antiracist education is necessary for teacher education programs because the grade …

An Exploration On Apts In Biocybersecurity And Cyberbiosecurity, Xavier-Lewis Palmer, Lucas Potter, Saltuk Karahan

School of Cybersecurity Faculty Publications

Novel and complex digital threats that are increasingly interwoven with means and products of biology that can affect society. Much work in Biocybersecurity/Cyberbiosecurity (BCS/CBS) discuss vulnerabilities, but few deeply address malicious actor varieties as attacks at this intersection are new. The path to those attacks remains mostly theoretical, presenting considerable difficulty to accomplish in practical scenarios. In terms of advanced persistent threats (APTs) this of course needs to change as biomanufacturing facilities are at risk, considering Covid-19 and other potential pandemics. Further attacks are not out of reach and thus we must start to imagine how BCS APTs may appear. …

A Zebra's Trust: How Rare Disease Communities' Participation In Data Trusts' Governance Builds Trust And Drives Research, Samantha C. Smith

Vanderbilt Journal of Transnational Law

Data sharing plays an increasingly prominent role in society, but it remains a necessary component of rare disease research. Because rare diseases are--as the name indicates-- rare, researchers have only a small number of patients from whom to collect data, and the expense of cross-border data sharing to increase research data is significant. Nevertheless, the rise of artificial intelligence and precision medicine increases the need for usable rare disease data. Current legislation and regulations aimed at addressing rare diseases fall short in addressing these data sharing needs for rare disease research. While the European Union (EU) has invested in rare …

System Statuses In Academic Libraries: Increasing Transparency And Improving The User Experience, Lauren Puzier, Rebecca A. Nous

University Libraries Faculty Scholarship

"is facebook down" trended on Google on October 4, 2021, when Facebook became temporarily globally unavailable. Web users proactively seek information when they encounter issues online. System status dashboards are one way libraries can leverage this behavior to share changes to resources or services and improve transparency, reference services, and the user experience. The University at Albany Libraries Discovery Services Librarian and User Experience Librarian implemented Springshare’s System Status Management tool to share system statuses with library staff and the campus community. The institutional context, implementation, and impact are described in this article. The authors reviewed Association of Research Libraries …

The Dissonance Between Knowing Animals Are Sentient Beings Yet Eating Them, Yana Bender, Juliane Bräuer

Animal Sentience

Animal sentience is linked to the bigger picture of climate and health crises and “carnism” is a factor in the dissonance among (1) knowing animals are sentient, (2) caring about their feelings, and (3) not acting accordingly. We discuss our responsibility as researchers and as individual human beings.

Intrinsic Motivation Is Not Enough: Exploring The Decision To Pursue Promotion To Full Professor, Margaret Roberts

University of the Pacific Theses and Dissertations

The academic career path for tenure track faculty in most four-year universities in the United States allows those who earn tenure to make an individual choice about whether to pursue promotion to the rank of full professor. Limited research exists on the intrinsic motivators that individuals possess and draw upon to push past obstacles or challenges they encounter along their academic career journey. This study explored the role of intrinsic motivation in the decision of tenured associate professors to pursue promotion to full professor. Using a basic qualitative research design, this inquiry involved two in-depth interviews each with seven participants. …

Investigation Of Cdk8 Inhibitor Q-12 Effects On Cdk8 And Cdk8 Substrates In Triple Negative Breast Cancer Cell Line Mda-Mb-468, Shengxi Li

University of the Pacific Theses and Dissertations

Cyclin-dependent kinases (CDKs) and cyclins (Cyclins) are the core molecules in the regulation mechanism of the entire cell cycle. Cell cycle dysregulation is a common feature of human cancers, and inhibitors of cyclin-dependent kinases (CDKs) play a crucial role in cell cycle control and are one of the most promising areas of cancer therapy. We aspired to use our cyclin-dependent kinase 8 (CDK8) inhibitor, Q-12, as a probe for biomarker discovery for CDK8 inhibitor sensitive tumor types. Q-12 shows potent inhibition of cell viability and induction of apoptosis process in some triple-negative breast cancer (TNBC) and colorectal cancer cell lines …

Microbial Community Analysis: Biofilm Inhibition & Algae Associated Community Structure, Michelle V. Fong

University of the Pacific Theses and Dissertations

Natural products chemistry is the pursuit of bioactive small molecules from living organisms. These can be classified as primary metabolites if they are essential to survival, and secondary metabolites if they are accessory, playing a role in communication, defense, recruitment, etc.. Natural products have made a significant contribution to society – of 1,881 FDA-approved drugs from 1981 to 2019, 4% were pure natural products, 19% were natural products derived, and 3% were synthetic drugs with a natural products pharmacophore targeting a wide range of diseases and infections (Newman & Cragg, 2020). Pharmacophores are structural components of drugs that are responsible …

Peripherally Restricted Delivery System Provides Insights On The Role Of Cns In Precipitating Opioid-Induced Constipation, Dengpan Liang

University of the Pacific Theses and Dissertations

A serious opioid crisis is affecting public health and economics, eroding people’s quality of life. 80% of patients who receive opioids suffer from adverse effects such as Opioid-induced constipation (OIC). However, there is no efficient medicine for these adverse effects. Notably, mainstream theory supports that analgesia effects are mainly controlled by CNS while OIC is predominately controlled by peripheral. In addition, the sites of action of opioid was based on the assumption that mu-opioid receptor antagonists (PAMORAs), did not cross the blood-brain barrier (BBB). Unfortunately, the BBB crossing of PAMORAs mislead the understanding of the role of the central nervous …

Utilization Of Virtual Reality For General Education Purposes, Amit Lal

University of the Pacific Theses and Dissertations

The use of Virtual Reality (VR) in a variety of professional, military, governmental, and educational fields has continued to expand over the past several decades, and the recent Covid-19 pandemic has brought attention to this field. This study surveys 154 college students over 23 questions that include various demographics that can be used to look for discriminators, multiple-choice VR-related questions, as well as a few free-form questions about use of VR in learning environments. The students’ experience with, interest in, and thoughts on how to best use VR vary considerably. The Covid-19 pandemic is found to have limited impact thus …

The Role Of Rad51 In Trichomonas Vaginalis, Dominique Hall

University of the Pacific Theses and Dissertations

Drug resistance to the current treatments on the market is on the rise, therefore there is strong interest in understanding what could be causing the resistance, how resistance could be spreading through the population, and finding some possible new drug targets. One protein of interest is Radiation Sensitive Protein 51 (Rad51). It is a protein that is involved in homologous recombination as well as other processes such as DNA damage repair. While Trichomonas vaginalis traditionally has been known to replicate via binary fission, a modified form of closed mitosis, there is some evidence that meiosis, or at least some form …

Spouses Of First Responders: A Narrative Inquiry Of Survival, Recovery And Healing, Jennifer D. Geiger

University of the Pacific Theses and Dissertations

The nature of the work of emergency responders (i.e., firefighters, law enforcement, paramedics, and dispatch) includes high stress and direct experiences of traumatic situations. The experience of posttraumatic stress is common. The spouse or significant other is often the first person to see a change in their responder and the person most likely to be sought out for support from the responder, yet there is little support for the spouses or significant others of emergency workers. The purpose of this qualitative study using in-depth interviews and narrative inquiry was to learn about participants’ experiences at the 6-day residential treatment (retreat) …

The Importance Of Building Positive Classroom Community For Adolescents After The Relational Disconnect From The Covid-19 Pandemic, Jessica Ann Swanson

All Electronic Theses and Dissertations

This paper aims to analyze the importance of providing students with a positive classroom environment that supports adolescent mental health. Middle school can be a time when students feel lonely, isolated, and oftentimes, it can be physiologically confusing as the body is transforming to becoming an adult. The Covid-19 pandemic exemplified the negative characteristics of normal adolescence. Research suggests that schools that incorporate belonging, relationship building, resilience training, community, and conflict resolution into the classroom can translate to academic success. Social-emotional learning programs can build community and improve adolescent mental health by promoting well-being. Addressing mental health through these types …

Our Place In Research: Understanding Social Productions Of Knowledge Using Digital Spaces, Allison C. Iafrate

Cal Poly Humboldt theses and projects

Academic research and research-writing are increasingly being recognized across disciplines as social and collaborative processes, involving many different voices and perspectives in the negotiation of meaning. However, within the context of the university classroom, research is often framed as an individualized process where students learn and perform research skills as single authors. This project approaches this discrepancy with a critical eye towards change by introducing digital spaces as a tool for reframing student perceptions of academic research. A selected review of literature is offered, which touches on topics such as critical research pedagogy, language varieties and language-play, multimodality and genres …

Uncertainty, Populist Deprivation Rhetoric, And Extremism, Crane Conso

Cal Poly Humboldt theses and projects

The present study investigates the influence of leadership messages on support for extremism using a social identity framework. Specifically, the study highlights the potential role of populist deprivation rhetoric and self-uncertainty in generating support for leaders and extremism. The study seeks to fill a gap in the existing research to understand the use of deprivation rhetoric as a direct process of populist leadership. Political extremism can serve to reduce feelings of uncertainty. Group relative deprivation results from a social comparison in which a person believes another individual or group is denying them something to which they feel entitled. Leaders can …

Resource Access And Equity In Humboldt County (How Social Myth Becomes Social Fact), Colton J. Hubbard

Cal Poly Humboldt theses and projects

Rural areas of Northern California have gone without health and social services for decades. The shortcomings of local services have given rise to the idea that there are no services in these rural and isolated communities. Conditions and beliefs have brought up two important questions. The first question is how can access and knowledge of available services be improved in rural areas? The second question is, through what mechanisms do communities develop their facts?

To address the previous questions, I worked with the primary health and social service provider in Humboldt County, CA. We developed a database of local services …

Nā Pua Makani Wind Farm: The Shifting Winds Of Renewable Development In HawaiʻI, George Webster Ross Iv

Cal Poly Humboldt theses and projects

In 2015, Hawaiʻi set the most ambitious renewable energy portfolio goal in the nation by vowing to reach 100% renewable energy by 2045. Since then, many renewable energy development projects in Hawaiʻi have been met with strong community opposition, including the Nā Pua Makani wind farm (NPM) in Kahuku. The aim of this project is to analyze the process timeline of NPM to identify factors in the development process that contributed to organized protest, and to offer recommendations for improving the process. In order to get a full picture of the events throughout the Nā Pua Makani project’s timeline, my …

Escherichia Coli And Salmonella Sp. In Domestic Cattle And Wild Roosevelt Elk: Fecal Pathogens At The Wildlife-Domestic Interface, Emily A. Buck

Cal Poly Humboldt theses and projects

Direct or indirect contact between domestic populations of animals and wildlife carries an inherent risk for transmission of pathogens that cause infectious disease. In Humboldt and Del Norte counties of northern California, ongoing conflict between ranchers and Roosevelt elk groups results from elk use of ranching pastures and pastures on private land. Fecal samples from elk in association with cattle, cattle, and from elk not in known association with cattle were assessed for the presence of bacteria Salmonella enterica and pathogenic Escherichia coli to assess whether association with cattle increases risk of infection for elk. Group identity (one of the …

Developing Standards For Gender-Responsive Human Rights Due Diligence, Constance Z. Wagner, Nancy Kaymar Stafford

All Faculty Scholarship

This article addresses the current state of gender-responsive human rights due diligence (GR-HRDD) standards and advocates for greater attention to be paid to women’s human rights in the due diligence process. The 2011 United Nations Guiding Principles on Business and Human Rights (UNGPs) created a global framework for recognizing, preventing, and addressing the risk of adverse impacts of human rights violations linked to business activities. The responsibility of businesses to respect human rights under the UNGPs includes implementing a human rights due diligence process. Although the UNGPs do not provide guidance on the process for integrating women’s rights into human …

Virtual Learning And Its Impact On Belonging And Mental Health, Chelsey Highley

Murray State Theses and Dissertations

This dissertation examined virtual learning and the link between sense of belonging and mental health. Specifically, this qualitative study assessed the perceptions and opinions of 15 high school students from a rural high school setting who participated in virtual learning for at least one semester during the COVID-19 pandemic. The research questions that guided this study were: (a) How did high school students experience belongingness with teachers and peers when engaged in virtual learning; and (b) How did high school students experience mental health issues during virtual learning? The data was collected via individual interviews and analyzed. The category emerging …

Factors Influencing Attitudes Towards Assistance Animals, Anna R. Ledonne

Murray State Theses and Dissertations

Service animals and emotional support animals are gaining a greater presence in many public spaces. The purpose of the following study is to explore attitudes towards service animals and emotional support animals in a more rigorous fashion than previous research and to explore possible predictors of people’s attitudes towards service animals and emotional support animals. Specifically, this study examined the following predictors: public and self-stigma against mental health, ableism, and attitudes towards pets or pet ownership. Data was collected utilizing an online survey distributed to an online general population sample (n = 105). A measure of attitudes towards service …

From Similarities To Probabilities: Feature Engineering For Predicting Drugs’ Adverse Reactions, Nahla Barakat, Ahmed Elsabagh

Artificial Intelligence

Social media recently became convenient platforms for different groups with common concerns to share their experiences, including Adverse Drug Reactions (ADRs). In this paper, we propose a two stage intelligent algorithm which we call “Simi_to_Prob”, that utilizes social media forums; for ranking ADRs, and evaluating the ADRs prevalence considering different age and gender groups as its first stage. In the second stage, ADRs are predicted utilizing a different data set from the Food and Drug Administration (FDA). In particular, Natural Language Processing (NLP) is used on social media to extract ranked lists of ADRs, which are then validated using novel …

Empowerment By Design: Classroom Innovation And Inquiry Through Design Thinking And Action Research, Cory Rayala

University of the Pacific Theses and Dissertations

Increasingly standardized and assessment-driven educational systems are failing to meet the needs of many students, replacing their love of learning with a fear of failure. Importantly, the fear of failure is a common mindset of not only students but also teachers, administrators, and policymakers. This qualitative, action research study is situated in a design thinking/growth mindset conceptual theory that posits that the design thinking process can serve as a meaningful growth mindset opportunity for teachers and students. The prototyping mindset inherent in design thinking may mitigate the fear of failure by focusing on rapid iteration rather than striving for perfection. …

Expression Of Mouse Full-Length Aryl Hydrocarbon Receptor And Human Aryl Hydrocarbon Receptor Ligand Binding Domain In Pichia Pastoris, Yiyuan Wang

University of the Pacific Theses and Dissertations

Aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that regulates biological responses to planar aromatic hydrocarbon. AHR activates gene transcription by binding to its corresponding enhancer with its partner-aryl hydrocarbon receptor nuclear translocator (ARNT). In addition, this receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. AHR exists widely in body tissues and affects bioactivation of carcinogenic compounds, T cell differentiation, fatty acid synthesis, cell proliferation, hematopoietic stem cell differentiation, respiratory reactivity, and insulin sensitivity. Although the precise mechanism illustrating the endogenous AHR function remains unclear, there has been intense interest in exploring AHR as a …

Social Movement Splintering: An Examination Of Stockton Stands With Minneapolis And News Media Representation, Kevin Ozomaro

University of the Pacific Theses and Dissertations

The phenomenon surrounding news media’s power to alter group identity and group cohesion is something that rarely a point of focus in communication studies. In this study I worked with a local social movement group called Stockton Stands with Minneapolis. This group illustrated the importance of maintaining shared values. Utilizing relational Interviewing, SSWM members provided evidence showing the connection between news media and group success. News media has had a role in shaping group members’ understanding of SSWM and activism. SSWM has faced internal conflict as a result of negative news representation. SSWM is a relatively small and young (2 …

Regulation Of Ppp1r15a (Gadd34) And Ppp1r15b (Crep) Mrna Expression And Localization In The Unfolded Protein Response, Krithika Giresh

University of the Pacific Theses and Dissertations

The failure to balance protein synthesis, folding, and degradation in the endoplasmic reticulum (ER) leads to the accumulation of unfolded proteins, leading to ER stress. Cells respond to this stress by activating a response signaling pathway known as the Unfolded Protein Response (UPR). One of the branches of the UPR induces the phosphorylation of eIF2α (Eukaryotic Initiation Factor 2) to attenuate global protein synthesis, allowing for a chance to clear misfolded and unfolded proteins. This phosphorylation of eIF2α is opposed by a phosphatase, containing a catalytic subunit, Protein Phosphatase 1, and a scaffolding protein, either GADD34 or CReP. Inhibition of …

Teacher Retention Policy Coherence: An Analysis Of Policies And Practices Across Federal, State, And Division Levels, Andrene Castro, Adria Hoffman, Jonathan D. Becker, David Naff, Peter S. Willis, Andy Kane

MERC Publications

As part of a larger MERC study, this report provides an overview of federal, state, and regional policies and practices relevant to teacher retention. Using key informant interviews and document analysis, the report addresses the following research questions: What teacher retention policies exist at the federal, state, and local levels? How are these policies structured at the state level and local levels? How do teacher retention policies vary across MERC divisions? Following the findings, the report presents recommendations for policy and practice.

Legal Recognition Of Animal Sentience: The Case For Cautious Optimism, Jane Kotzmann

Animal Sentience

Rowan et al.’s target article provides a valuable indication of the work that was required to reach the point where animals are recognised as sentient in various laws. To ensure this work was not in vain, the language of sentience needs to be used as a moral currency to demand further cultural change involving greater human respect for animals.

Annual Report Of The Registrar 2021/2022, University Of Northern Iowa

Institutional Effectiveness & Planning Documents

Contents:

--Definitions
--Some Comparisons
--Annual Report Data
--Summary of Attendance
--Attendance by Session
--Degrees Granted 2021/22
--Degree Summary 2021/22
--Program Certificates 2021/22
--Miscellaneous Enrollment Information
--Degrees Granted by College, Degree and Racial/Ethnic Classification

Cyber Whistleblowers: The Black Sheep Of Whistleblowing?, Andrew Wisniewski Jr.

Cybersecurity Undergraduate Research Showcase

From the Introduction:

Contrary to popular belief, this paper argues that cyber whistleblowing can contribute to a greater cyber security posture. However, this requires the development of clearer legal obligations and protections for cyber whistleblowers. This paper will explore the psychology behind whistleblowing, the effectiveness of whistleblowing in a cybersecurity context, how to create a safer and more transparent environment for whistleblowers and companies, and how current laws contribute to cyber whistleblowing.