Digital Commons Network^™

Understanding Alcohol Use Discourse And Stigma Patterns In Perinatal Care On Twitter, Fritz Culp, Yuqi Wu, Dezhi Wu, Yang Ren, Phyllis Raynor Phd, Aprn, Pmhnp-Bc, Peiyin Hung Ph.D, Shan Qiao Ph.D., Xiaoming Li Ph.D., Kacey Eichelberger

Publications

(1) Background: perinatal alcohol use generates a variety of health risks. Social media platforms discuss fetal alcohol spectrum disorder (FASD) and other widespread outcomes, providing personalized user-generated content about the perceptions and behaviors related to alcohol use during pregnancy. Data collected from Twitter underscores various narrative structures and sentiments in tweets that reflect large-scale discourses and foster societal stigmas; (2) Methods: We extracted alcohol-related tweets from May 2019 to October 2021 using an official Twitter search API based on a set of keywords provided by our clinical team. Our exploratory study utilized thematic content analysis and inductive qualitative coding methods …

Utilization Of Positive Youth Development Framework By Youth-Facing Organizations In Baltimore City, Selvi Rajagopal, Kaitlyn Harper, Katherine Holzhauer, Tina Kumra

Journal of Youth Development

Positive youth development (PYD) is a strengths-based approach to youth programming which has been tested with success in largely higher income settings with mostly White youth. This study aims to identify the extent to which organizations who work in an urban context serving predominately African American youth incorporate PYD principles into their work. Organizations located in Baltimore, Maryland working with youth ages 14–24 were recruited for participation. In-depth interviews were conducted with organization leaders in this qualitative study. Thematic analysis using a deductive approach identified common themes and activities across organizations that aligned with PYD elements. All 17 youth-facing organizations …

Lgd-4033 And Mk-677 Use Impacts Body Composition, Circulating Biomarkers, And Skeletal Muscle Androgenic Hormone And Receptor Content: A Case Report, Thomas D. Cardaci, Steven B. Machek, Dylan T. Wilburn, Jeffery L. Heileson, Dillon R. Harris, Harry P. Cintineo, Darryn S. Willoughby

Kinesiology Faculty Publications and Presentations

LGD-4033, a selective androgen receptor modulator, and MK-677, a growth hormone secretagogue, are being used increasingly amongst recreationally active demographics. However, limited data exist describing their effects on health- and androgen-related biomarkers. The purpose of this case study was to determine changes in body composition and biomarkers during and after continued co-administration of LGD-4033 and MK-677. We also aimed to examine muscular strength and intramuscular androgen-associated biomarkers relative to non-users. A 25-year-old male ingested LGD-4033 (10 mg) and MK-677 (15 mg) daily for 5 weeks. Blood and body composition metrics were obtained pre-, on- and post-cycle. One-repetition maximum leg and …

Educational Technology Workshops For The Seniors Adults, Maria Guadalupe Martinez Bribiesca

Capstone Projects and Master's Theses

The City of Watsonville Parks and Community Services works with various ages, from toddlers to seniors, depending on the program or organization. The main focus of this project was to work towards keeping seniors up to date with advanced technology. The problem was that many seniors don’t have the knowledge when it comes to using technology properly. The project's purpose was to educate as many senior citizens with basic computer skills. The workshop was offered both in Spanish and English once every month. The individual appointments are every week on Tuesdays. The project has exceeded expectations. The individual appointments get …

How Sample Clearance Has Affected Hip-Hop Music-Making, Bryan J. Brewster

Capstone Projects and Master's Theses

This paper will explain how sample clearance has impacted hip-hop music-making. It will explain what a sample is and show the historical significance of sampling in hip-hop. I will briefly discuss the basics of copyright and the process of clearing a sample. This paper will also look into legal cases of copyright infringement to show the impact of specific cases and analyze data to determine if the amount of sample clearance has changed because of the decisions of the courts. The main goal of this paper is to highlight the significance of sampling in hip-hop, the inherent challenges of legally …

Impact Of Online Learning On Academic Success Of College Students, Natalie Carbonel

Capstone Projects and Master's Theses

Online learning has become more prominent in higher education institutions due to the recent COVID-19 pandemic and has ultimately impacted the academic success of college students. The purpose of this capstone is to examine the impact of online learning on the academic success of college students. Through the use of literature review and a survey with 20 students at the community college and four-year colleges, the findings reveal that online learning has negatively impacted their attitude, motivation, self-efficacy and accessibility toward learning. This capstone concludes with suggestions on ways to improve their attitudes and acceptance of the adaptation of the …

Helping Immigrant Children Cope With Stress And Anxiety, Fatima Luna

Capstone Projects and Master's Theses

Besides physical health, mental health is a critical component of every person’s well-being starting from childhood. In the United States, stress and anxiety are one of the most common mental disorders in children. Occasionally, parents and the environment put much pressure on a child resulting in anxiety; at times, parents’ anxiety is projected onto their kids. Teaching children how to cope with daily stressors and anxiety is crucial to their development. This project focused on teaching Hispanic children about managing stress and anxiety through mindfulness. While also learning about how to seek help and express negative emotions. To help children …

Conscious Discipline For Parents Of Preschool Aged Children, Claire Seabock

Capstone Projects and Master's Theses

This capstone project focuses on the benefits of conscious discipline for both the parent and the child. Conscious parenting is a type of parenting style that asks the parent to consciously look into the way they interact and respond to their child’s behavior. The relationship between the parent and child from two to five years old sets the foundation for a secure attachment between a parent and child during the middle childhood, teenage and early adulthood years. Conscious parenting is a parenting style that helps the parent understand the needs of their children to better help them regulate their emotions. …

Effects Of Sediment Addition On Macroinvertebrate Communities In New England Salt Marshes, Chloe Brownlie

Master's Theses and Capstones

Salt marsh invertebrates play a vital role in salt marsh ecosystems by aerating the marsh, cycling nutrients, and forming connections between trophic levels, but the impacts of large-scale natural and anthropogenic sediment addition on their community structure and species composition is poorly understood. During winter storm Grayson in January of 2018, ice rafting caused large areas of sediment to deposit on significant areas of the Great Marsh in Massachusetts. I hypothesized that sediment addition would influence the abundance and richness of invertebrates in the marsh, because they tend to take years to recover after a disturbance. Sediment cores were taken …

The Cowl - V. 87 N. 8 - December 1, 2022

The Cowl

The Cowl - student newspaper of Providence College. Vol. 87 No. 8 - December 1, 2022. 16 pages.

St. Norbert College Announces J-Term Courses, St. Norbert College

Press Releases 2022

No abstract provided.

Uncloaking Cell-Impermeant Gold Nanorods Via Tumor Microenvironmental Cathepsin B Facilitates Cancer Cell Penetration And Potent Radiosensitization, Subhiksha Raghuram, Yuri Mackeyev, Jessica Symons, Yasmin Zahra, Valeria Gonzalez, Krishnan K Mahadevan, Katherinne I Requejo, Anton Liopo, Paul Derry, Eugene Zubarev, Onur Sahin, Joseph Byung-Kyu Kim, Pankaj K Singh, Sang Hyun Cho, Sunil Krishnan

Faculty, Staff and Student Publications

Major impediments to conveyance of intravenously administered drugs to tumors are biofouling, opsonization, and rapid clearance from the circulation by macrophages and reticuloendothelial phagocytes. Cloaking nanoparticles with stealth epilayers partly overcomes these hurdles but it also foils interactions with tumor cells. Here, we describe the synthesis, characterization, and validation of smart gold nanorods (GNRs) that spontaneously transform from inert passengers in the blood stream to active cell-penetrating nanoparticles within tumors to potently sensitize tumors to radiation therapy. Intrinsically cationic and cell-penetrating GNRs were shielded from phagocytosis with a cloaking polyethylene glycol epilayer containing an intervening cleavable peptide. In the absence …

A Numerical Simulation Of The Powder Bed Additive Manufacturing Process With Molecular Dynamics Simulation, Yeasir Mohammad Akib

Theses and Dissertations

Many manufacturing industries utilize powder bed fusion (PBF) since it can produce microscale precision 3D parts. During PBF, powder particles are selectively fused layer by layer using thermal energy. The build quality in the PBF process relies heavily on powder bed properties and thermal energy deposition. Powder flowability, spreadability, and packing fraction are some of the insightful factors that determine the quality of the powder bed. In this study, a two-dimensional powder bed is developed using the LAMMPS package. A cloud-based pouring of powders with varying volumes and initialization is adopted for the work. A blade-type and circular recoater is …

Arab American Muslims’ Attitudes Toward Seeking Mental Health Services: The Roles Of Acculturation, Religion, And Cultural Beliefs, Tharwah Alzoubi

Theses and Dissertations

The purpose of this study was to identify the relationship between acculturation, religion, cultural beliefs, and attitudes toward seeking mental health services among Arab American Muslims. A total of 280 participants were surveyed for this study. Regression analysis was conducted to explore relationships among the variables; the alpha level was set at .05. The first research hypothesis was accepted as it showed statistical significance in the relationship between attitudes toward seeking mental health services and demographic variables. The standardized regression coefficients, or beta coefficients ranged from -.008 for gender to .24 for marital status, R=.31 (P<.05). Two variables were significant at the .05 level (marital status, and health insurance). The second hypothesis was also accepted as it showed relationship between attitudes toward mental health services and acculturation, religion and cultural beliefs; the standardized regression coefficients, or beta coefficients ranged from .05 for cultural beliefs to a -.25 for religion, R=.44 (P<.05). The variables of acculturation and religion were significant at the .01 level. Cultural beliefs were not significant at .05 level.

The Molecular Evolution Of Insect Opsin Genes, Maria Jose Cardenas Muedano

Theses and Dissertations

Opsins are part of the superfamily of G-coupled receptor proteins and together with chromophores, are responsible for initiating the signal transduction cascade responsible for animal vision. Since opsins have a critical role on visual perception these genes are crucial for a myriad of adaptive traits and behaviors and should show diverse signs of natural selection at the molecular level. Understanding the evolution of opsins across the wide diversity of insect groups will allow us to better understand the evolutionary pressure on insect opsins and serve as a model for both other gene systems and other taxonomic groups of animals that …

Green Synthesis Of Spiro Compounds And The Phytochemical Investigation Of Diethyl Ether Fraction Of Camu-Camu (Myrciaria Dubia) Leaves, Judith Anane

Theses and Dissertations

There are a lot of lucrative plant species found in the Amazon and camu-camu (Myrciaria dubia (H.B.K.) Mc Vaugh) is distinct among them. This is due to its exceptional Vitamin C content which varies from 1600 to 6112 mg/100g of pulp. Besides the fruits which is popularly used, different parts of camu-camu plants including the stems, leaves, seeds, barks, and roots are also traditionally used in folklore practices for treating various ailments and diseases and research has showed the presence of antioxidant, antimicrobial, anticancer, anti-inflammatory agents present in these parts. In this study, the characterization of a bioactive compound, …

Conjunctive Management For Groundwater-Surface Water Resources: Numerical Modeling And Potential Assessment Of Managed Aquifer Recharge (Mar) At Lower Rio Grande Valley In South Texas, Dwight Zedric Q. Capus

Theses and Dissertations

Texas is well known to frequent floods and droughts, and yet has mounting concerns in very imbalanced water availability and water demands from growth in population and economical activities. Capturing and storing water is essential to long-term and climate-smart management of the “already-scarce” water resources. This study aimed to apply numerical modeling to evaluate potentials and impacts of Managed Aquifer Recharge (MAR) to regional groundwater systems in the Lower Rio Grande Valley. Using Visual MODFLOW Flex 3D package, different scenarios were simulated for groundwater flow patterns and storage capacities. Water injections tested ranged between 7.30x105 ft3 to 3.65x109 ft3 , …

Monsters & Men, Christopher Ernest Garcia

Theses and Dissertations

Monsters & Men is a collection of poetry and illustrations that explores the complex emotions associated with masculinity, grief, and personal development. I achieve this by heavily reflecting on my relationship with my late father and using this medium as an outlet to express my trauma in a healthy manner. How we perceive ourselves as men, and what is possible, is not reflected enough in society and I aim to be a proponent in stimulating the conversation revolving around men’s mental health. Men and the patriarchy impose themselves on others to the point where we need to address the unethical …

The Mediating Role Of Gun Attitudes In The Association Between Dsm-5 Posttraumatic Stress Disorder Symptom Clusters, And Gun Ownership In Young Hispanic Adults With Exposure To Interpersonal Trauma, Vanessa Gonzalez

Theses and Dissertations

Despite growing interest in gun attitudes and gun ownership among United States citizens, the current body of literature is limited and tends to focus on white non-Hispanic individuals. The present study examined the effect of interpersonal trauma-related PTSD symptoms on gun attitudes and protective gun ownership. The associations between experiencing PTSD symptoms, gun attitudes, and protective gun ownership were examined in a sample of 176 young Hispanic adults (n = 127 women, n = 49 men) with exposure to interpersonal trauma. Specifically, the mediating role of positive attitudes towards guns in the associations between the four clusters of DSM-5 …

Atomlbs: An Atom Based Convolutional Neural Network For Druggable Ligand Binding Site Prediction, Md Ashraful Islam

Theses and Dissertations

Despite advances in drug research and development, there are few and ineffective treatments for a variety of diseases. Virtual screening can drastically reduce costs and accelerate the drug discovery process. Binding site identification is one of the initial and most important steps in structure-based virtual screening. Identifying and defining protein cavities that are likely to bind to a small compound is the objective of this task. In this research, we propose four different convolutional neural networks for predicting ligand-binding sites in proteins. A parallel optimized data pipeline is created to enable faster training of these neural network models on minimal …

The Persistence Of Racist Violence In The Rio Grande Valley, 1921-1927, Vincent A. Larralde

Theses and Dissertations

This thesis examines the conditions that led to the violence orchestrated by Texas Rangers during La Matanza, and how after the Porvenir Massacre of 1918, state reform initiatives resulted in an investigation of the Texas Rangers in 1919. As a result, they were reduced in force and capability, and modern-day scholars imply violence associated with La Matanza ceased in the Valley after that.

However, this thesis argues that racist violence did not disappear but continued in the 1920s. Posses continued the administration of racist violence and lynching against ethnic Mexicans. Therefore, this thesis examines one case in Cameron County in …

Femtosecond Pulse Filamentation In Dielectric Media Toward Photonics Sensor Fabrication, Anitha Narayanan

Theses and Dissertations

Through pulse filamentation, femtosecond laser pulses have been utilized to modify the refractive indices of dielectric materials such as glass, A-plane sapphire crystal, and Cplane sapphire crystal. The 10x Infinity Corrected Lens was used, and the focusing condition was tuned as being the same and fixed to both glass and sapphire crystals. First, 8uJ of laser energy was optimized to produce controlled pulse filamentation voids in the glass. The laser intensity was then optimized to 2-3.5 uJ, 1.5 uJ, & 2.5 uJ, respectively, for the controlled pulse filamentation in A and C plane sapphire crystals. Due to the different crystal …

Examination Of The Attitudes Towards Substance Use Treatment Approaches By Substance Use Professionals, Cameron Lacy Ortega

Theses and Dissertations

This quantitative study focuses on substance use professionals and students who are seeking employment in substance use treatment or support services. The substance use treatment profession started as a group of people who were supporting each other in recovery through abstinence based practices and has developed in to a recognized profession with multiple methods of treatment approaches. Abstinence based treatment has been and continues to be the primary method of treatment preferred in the United States. Since the 1980, harm reduction increased in application in the profession, but remains a less popular method of treatment. This study examines substance use …

Effects Of Roundup Exposure On Redox Status, Cellular Apoptosis, And Antioxidant And Osmoregulatory Enzyme Expressions In Goldfish (Carassius Auratus), Md Imran Noor

Theses and Dissertations

Intense anthropogenic activities of industrialized nations dramatically increase environmental pollution. This study focused on the effects of Roundup, a glyphosate-based herbicide, exposure (low- and high-dose: 0.5 and 5 mg/L for 2 weeks) on dinitrophenyl protein (DNP), nitrotyrosine protein (NTP), superoxidase dismutase (SOD), catalase (CAT), Na+ /K+ - ATPase (NKA), and renin expressions, and cellular apoptosis in the gills and kidneys of goldfish. Histopathological analysis showed widespread tissue damage in both gills and kidneys. Immunohistochemical analysis provided insights into the expression of molecular biomarkers in tissues. Fish exposed to Roundup exhibited a significant (P<0.05) upregulation in DNP, NTP, SOD, and CAT expressions, and apoptotic nuclei in both tissues. Additionally, exposure to Roundup significantly increased renin expression in kidneys and decreased NKA expression in gills. Overall, our results suggest that exposure to Roundup induces oxidative/nitrative stress and cellular apoptosis and alters osmoregulatory and antioxidant systems which may lead to impaired physiological functions in goldfish.

Growing Up Butchona On The Texas-Mexico Border A Marimacha Memoir, Julietta Rivera

Theses and Dissertations

Growing Up Butchona on the Border is a queer, Latina memoir that takes place on the Texas-Mexico border. This thesis is a journey in words and pictures that spans throughout an immigration crisis, a worldwide pandemic and the fallout that follows a world-wide lockdown; eventually leading down the rocky road to self-discovery. The thesis opens with a fictional account of Torita Torcida, a seven-year-old Honduran immigrant that makes her way across the Texas-Mexico border with her mother only to be ripped away from her when the truck they were smuggled in is seized by border patrol. Images and words come …

Foxo Factors Regulate The Expression Of Canonical Wnt Target Genes In A Set Of Basal-Like Breast And Glioblastoma Multiforme Cancer Cell Lines, Shania Pintor

Theses and Dissertations

Basal-like breast cancer (BBC) and Glioblastoma Multiforme (GBM) each express stem gene expression signatures which are partly driven by FOXO transcription factors. Preliminary data from Gene Set Enrichment Analysis (GSEA) with RNA Seq. data indicated that a set of WNT target genes including LEF1, and TCF7 were robustly induced after 48-hours of AS1842856 (FOXO1 inhibitor) treatment. These same genes were also induced in GBM cell lines U87MG, LN18, LN229, A172, and DBTRG upon treatment with AS1842856. In contrast to FOXO1 inhibition, RNAi targeting of FOXO1, led to reduced LEF1, and TCF7 gene expression in BT549 and U87MG …

Influence Of Glucose And Lactic Acid On Macrophage Transition In Pancreatic Tumors, Anyssa A. Rodriguez

Theses and Dissertations

Pancreatic cancer is the seventh leading cause of cancer-related mortality worldwide. According to the American Cancer Society, it is the eleventh most common cancer diagnosed in both men and women in the United States. Pancreatic ductal adenocarcinoma (PDAC) comprises 90% of all pancreatic malignancies and is associated with poor clinical outcome because of late diagnosis and resistance to therapy. In addition, studies show that the tumor microenvironment has become an emerging interest in cancer research due to its complex components and unique characteristics that aid in cancer initiation, maintenance, and progression. Accumulating evidence signifies that tumor associated macrophages (TAMs) play …

Numerical Simulation Of Vibration - Based Piezoelectric Energy Harvester For Shape Comparison, Adriana Rosas

Theses and Dissertations

This work investigates the shape optimization of piezoelectric energy harvesters subjected to mechanical vibration using ABAQUS/Standard software. Three piezoelectric energy harvesters with different dimensions but the same areas were created to identify if model dimensions have an impact on the output voltage. The models were tested at different speeds to create an output voltage. Once the output voltages were obtained, the results were compared with each other to find if shape optimization on piezoelectric energy harvesters has an impact on scavenging energy from mechanical vibrations.

Como Lo Recuerdo: A Remembrance Of Mexican Folk Songs From Our Residents’ Hearts, Arturo Treviño Jr.

Theses and Dissertations

Educators today face the challenge of finding either the individual in the community or the community in the individual. This study applies Jeff Titon's idea on communities as musical ecosystems to explore the sustainability of John A. Lomax's April 1939 Southern Collection field recordings, examining how and where these musical works exist in Brownsville, Texas today and investigating the meanings of these Mexican folk songs to Rio Grande Valley community members. In this work, I put the Lomax song collection in greater cultural, historical, and musical context, and argue that the songs can assist Rio Grande Valley individuals in both …

Abusing Discretion: The Battle For Childhood In Schools, Hannah Dodson

Michigan Journal of Race and Law

For too many children the schoolhouse doors become a point of entry into the criminal justice system. Children of color are the most likely to suffer from this phenomenon. The presence of policing in schools is a key contributor to this “school-to-prison pipeline.” This Note argues that broad, discretionary mandates for school resource officers (SROs) promote biased law enforcement that impacts Black girls in different and specific ways. I contend that SRO mandates can be effectively limited by strategically bolstering community organizing efforts with impact litigation.