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2022

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Why Anti-Racist Education Must Include Asian American History, Leanne Kang Jan 2022

Why Anti-Racist Education Must Include Asian American History, Leanne Kang

Mid-Western Educational Researcher

This is a commentary on why anti-racist education must include Asian American history, especially in the wake of increased hate crimes against Asians and anti-Asian bullying in schools during the COVID-19 pandemic. The first half of the paper discusses the issue and how the absence of Asian American history in K-12 and teacher preparation programs plays a role in perpetuating racism against Asians in the U.S. The second half of the paper presents how I have incorporated Asian American history into a social foundations of education course through two legal cases filed by Chinese Americans: Tape v. Hurley (1885) and …


Perceptions Of Black First-Generation College Students Regarding The Impact Of Recruitment Practices At A Predominantly White Institution During The Covid-19 Pandemic, Deann Handy Walter Jan 2022

Perceptions Of Black First-Generation College Students Regarding The Impact Of Recruitment Practices At A Predominantly White Institution During The Covid-19 Pandemic, Deann Handy Walter

Electronic Theses and Dissertations

In 2020, the coronavirus disease (COVID-19) plagued the United States, becoming one of the greatest disruptions to the U.S. higher education system in history. Affecting every aspect of institution’s operations, prospective fall 2020 and beyond students were impacted greatly by the interruption of traditional college recruitment practices which would have occurred as they made their enrollment decisions. Most affected by this interruption were students of underrepresented groups. This dissertation focuses particularly on Black first-generation students and their perceptions regarding the impact of recruitment practices at a Predominantly White Institution during the COVID-19 pandemic. A qualitative study is proposed as the …


Will Covid-19 Be Eradicated?, Matthew Kieke Jan 2022

Will Covid-19 Be Eradicated?, Matthew Kieke

Williams Honors College, Honors Research Projects

In this paper I want to define the meaning of “eradication”, explain the history of various diseases that have been eradicated, and compare and contrast them to covid-19, to answer the question of “Will covid-19 be eradicated”?


Themes And Associations Concerning The Covid-19 Pandemic: Autoethnography, Amber Mcgannon, Ebunoluwa O. Adedeji Jan 2022

Themes And Associations Concerning The Covid-19 Pandemic: Autoethnography, Amber Mcgannon, Ebunoluwa O. Adedeji

Williams Honors College, Honors Research Projects

Per the college of nursing, my proposed project will discuss living during uncertain times and unusual times of change. This APA formatted paper will be an autoethnography, meaning that we will review the perspectives of COVID through the lens of culture, research, and our own perspectives and experiences. Everyone has experienced changes during the COVID-19 pandemic due to self-isolation. Examples of change include changes in learning, working, thinking, teaching, and behaving. Using acquired nursing skills such as critical thinking, reflection, inquiry, and evidenced-based practice; my partner and I will dissect and discuss these changes and how they have affected ourselves, …


Auto- Ethnography With A Deep Dive Into Changes Mental Health During The Pandemic And A Look Into The Way The Pandemic Has Shaped Nursing Protocols For Recent Nursing College Graduates, Audrey Shaffer, Sarah Bereznay Jan 2022

Auto- Ethnography With A Deep Dive Into Changes Mental Health During The Pandemic And A Look Into The Way The Pandemic Has Shaped Nursing Protocols For Recent Nursing College Graduates, Audrey Shaffer, Sarah Bereznay

Williams Honors College, Honors Research Projects

In this project we completed a deep dive into how the Covid-19 pandemic reshaped our mental health and has affected our preparation for careers as registered nurses through a series of auto- ethnographic narrative journals using scholarly articles to support this idea. By utilizing personal narratives, we analyzed and reflected upon the cognitive and mental changes we experienced throughout this pandemic. We fulfilled this by comprising two personal narratives with inquiries pertaining to each shared narrative by utilizing the common themes of being nursing students and living through a pandemic. Within these personal narratives, we discussed how the pandemic influenced …


Emergency Water Treatment Methods Through The Adaptation Of Natural Disaster Building Debris, Benjamin Colston Jan 2022

Emergency Water Treatment Methods Through The Adaptation Of Natural Disaster Building Debris, Benjamin Colston

Williams Honors College, Honors Research Projects

The primary objective of this research was to determine whether concrete slag acquired from building debris in a disaster can be utilized to remove pathogens biochemically through changes in pH or physically through filtration. Direct Plate Enumeration testing was completed for different water samples to compare the general activity of bacterial growth as an indication of pathogenic potential. Throughout each experiment, the pH of different water samples was monitored and consistently indicated that water samples in contact with concrete pieces (concrete water samples) would exhibit a higher pH than samples with no exposure to concrete (control water samples). Compared to …


Retention And Stability Of Polystyrene Sulfonic Acid And Polyethylene Glycol Anti- Fouling Films With 3-Aminopropyltriethoxysilane Coupling Agent, Brian Cameron Jan 2022

Retention And Stability Of Polystyrene Sulfonic Acid And Polyethylene Glycol Anti- Fouling Films With 3-Aminopropyltriethoxysilane Coupling Agent, Brian Cameron

Williams Honors College, Honors Research Projects

Fouling is a process where particles, proteins, or microorganisms will accumulate onto a material [2]. This can lead to biofilms in medical implants, which can trap and create drug resistant bacteria [5]. Due to this, the study and creation of anti-fouling polymeric films that is stable in aqueous environments is essential. The goal of this study is to utilize APTES to retain the already studied PSS-PEG anti-fouling films. The films that are created is a thermally crosslinked network of the polystyrene sulfonic acid (PSS) and polyethylene glycol (PEG) with differing mass fractions (75- 25 and 55-45 PSS-PEG). To retain the …


Smart Low-Cost Thermal Imaging Acquisition Towards Personal Comfort Prediction, Ati Soleimanijavid, Iason Konstantzos Jan 2022

Smart Low-Cost Thermal Imaging Acquisition Towards Personal Comfort Prediction, Ati Soleimanijavid, Iason Konstantzos

International High Performance Buildings Conference

No abstract provided.


Preventing Opioid Addiction In Benton And Franklin County, Washington, Tracie Hicks Jan 2022

Preventing Opioid Addiction In Benton And Franklin County, Washington, Tracie Hicks

Selected Social Change Portfolios in Prevention, Intervention, and Consultation

Goal Statement: Prevention of opioid addiction in Benton and Franklin County, WA through the implementation of effective strategies, resources, and prevention programs.

Significant Findings: Opioid addiction is a significant public health crisis in the United States costing approximately $78.5 billion a year (NIDA, 2021). Both Benton and Franklin County, Washington have been impacted by the national opioid epidemic. Statistics show that in Benton County between 2018-2020 there was a 169.8% increase in opioid deaths and Franklin County experienced a staggering 289.2% increase in opioids deaths in 2018-2020 (Addictions, Drug, and Alcohol Institute, 2021). Research indicates that prevention and advocacy programs …


Humidity Reduces Rapid And Distant Airborne Dispersal Of Viable Viral Particles In Classroom Settings, Antun Skanata, Fabrizio Spagnolo, Molly Metz, Davida S. Smyth, John J. Dennehy Jan 2022

Humidity Reduces Rapid And Distant Airborne Dispersal Of Viable Viral Particles In Classroom Settings, Antun Skanata, Fabrizio Spagnolo, Molly Metz, Davida S. Smyth, John J. Dennehy

Publications and Research

The transmission of airborne pathogens is considered to be the main route through which a number of known and emerging respiratory diseases infect their hosts. While physical distancing and mask wearing may help mitigate short-range transmission, the extent of long-range transmission in closed spaces where a pathogen remains suspended in the air remains unknown. We have developed a method to detect viable virus particles by using an aerosolized bacteriophage Phi6 in combination with its host Pseudomonas phaseolicola, which when seeded on agar plates acts as a virus detector that can be placed at a range of distances away from an …


Preparing For Professional Programs: Strategies And Practices For Pre-Medical Education, April Elayne Curry Jan 2022

Preparing For Professional Programs: Strategies And Practices For Pre-Medical Education, April Elayne Curry

Theses and Dissertations

This study examines the preparation process for students in professional programs and highlights strategies and practices for pre-medical education. The COVID-19 pandemic has highlighted elements of the healthcare system that explore how critical physicians are that can lead with both a global perspective and with compassionate patient care. In order to understand the competencies required for this leadership process, it is critical to consider the medical school lifecycle from the undergraduate education to residency. Working from the admissions process, we consider what competencies are required for medical school success and physician preparedness and we use that to shape a solid …


Understanding The Underserved Student: Barriers Experienced By At-Risk Students During The Covid-19 Pandemic, Melissa Rosado Jan 2022

Understanding The Underserved Student: Barriers Experienced By At-Risk Students During The Covid-19 Pandemic, Melissa Rosado

Theses and Dissertations

The forced expeditious transition online induced by the COVID-19 pandemic caused a massive disruption to education. COVID-19 exacerbated the inequities that existed in education for years. As technology advances and integrates with education, it can both enhance inclusive instructional practices, as well as exacerbate issues of equity. Achievement gaps will persist unless colleges create equitable educational environments for all students, including “at-risk” populations such as those enrolled in the Extended Opportunity Program and Services (EOPS) program—a state funded equity program.

Through the lens of digital equity and inclusion theoretical frameworks, the purpose of this embedded mixed methods study was to …


The Shades Of Immigration: How Skin Tone Shapes Attitudes Towards Venezuelan Immigrants In Latin America, Madison Hamilton Jan 2022

The Shades Of Immigration: How Skin Tone Shapes Attitudes Towards Venezuelan Immigrants In Latin America, Madison Hamilton

Electronic Theses and Dissertations

Venezuela is currently home to one of the most profound economic crises in modern-day Latin America and the most severe in any non-war-ridden country in recent years. Due to this, mass amounts of Venezuelan immigrants have left to countries such as Colombia, Chile, Ecuador, and Peru. This immigration within Latin America, with similar culture and language, leads to the question of if and how does skin tone predict attitudes towards Venezuelans in several Latin American countries? This study uses data from the 2018/19 LAPOP data survey to assess the link between skin tone and support for Venezuelan immigrants. Results of …


Shying Away From The Shot: A Qualitative Analysis On Vaccine Hesitancy At Uab Huntsville Family Medicine Clinic, Nadia Anabtawi, Roger D. Smalligan, Gayatri Venkatraman Jan 2022

Shying Away From The Shot: A Qualitative Analysis On Vaccine Hesitancy At Uab Huntsville Family Medicine Clinic, Nadia Anabtawi, Roger D. Smalligan, Gayatri Venkatraman

UAB Huntsville Research Day - All Presentations

2022 oral presentation


A Rare Presentation Of Acute Acalculous Cholecystitis In A Patient With Acute Hepatitis A, Oseyime Okoeguale, Rafik Elbeblawy, Jimmy Molyneux, Roger Smalligan Jan 2022

A Rare Presentation Of Acute Acalculous Cholecystitis In A Patient With Acute Hepatitis A, Oseyime Okoeguale, Rafik Elbeblawy, Jimmy Molyneux, Roger Smalligan

UAB Huntsville Research Day - All Presentations

2022 clinical vignette poster


Longevity Of An Immunocontraceptive Vaccine Effect On Fecundity In Rats, Rebecca Pinkham, Douglas C. Eckery, Richard E. Mauldin, M. Gomm, F. Hill, F. Vial, G. Massei Jan 2022

Longevity Of An Immunocontraceptive Vaccine Effect On Fecundity In Rats, Rebecca Pinkham, Douglas C. Eckery, Richard E. Mauldin, M. Gomm, F. Hill, F. Vial, G. Massei

United States Department of Agriculture Wildlife Services: Staff Publications

Increases in human-wildlife conflicts alongside cultural shifts against lethal control methods are driving the need for alternative wildlife management tools such as fertility control. Contraceptive formulations suitable for oral delivery would permit broader remote application in wildlife species.

This study evaluated the contraceptive effect and immune response to two novel injectable immunocontraceptive formulations targeting the Gonadotropin Releasing Hormone (GnRH): MAF-IMX294 and MAF-IMX294P conjugates, both identified as having potential as oral contraceptives. The study also explored whether in multiparous species immunocontraceptives may either totally prevent reproduction or also affect litter size.

Female rats, chosen as a model species, were given three …


Rapid Changes In Public Perception Toward A Conservation Initiative, Rebecca Niemiec, Richard E.W. Berl, Mireille Gonzalez, Tara L. Teel, Jonathan Salerno, Stewart Breck, Cassiopeia Camara, Matthew Collins, Courtney Scholtz, Dana Hoag, Kevin R. Crooks Jan 2022

Rapid Changes In Public Perception Toward A Conservation Initiative, Rebecca Niemiec, Richard E.W. Berl, Mireille Gonzalez, Tara L. Teel, Jonathan Salerno, Stewart Breck, Cassiopeia Camara, Matthew Collins, Courtney Scholtz, Dana Hoag, Kevin R. Crooks

United States Department of Agriculture Wildlife Services: Staff Publications

Rapid, widespread changes in public perceptions and behaviors have the potential to influence conservation outcomes. However, few studies have documented whether and how such shifts occur throughout the span of a conservation initiative. We examined the 2020 ballot initiative to reintroduce wolves into Colorado, which passed with less support than prior surveys had estimated. We conducted a postelection survey of Colorado residents using the same methods as our preelection survey to compare responses between surveys and to official election results. Reported voting in favor of wolf reintroduction in the postelection survey decreased in comparison to voting intentions shared in the …


A Model For Leveraging Animal Movement To Understand Spatio-Temporal Disease Dynamics, Mark Q. Wilber, Anni Yang, Raoul Boughton, Kezia R. Manlove, Ryan S. Miller, Kim M. Pepin, George Wittemyer Jan 2022

A Model For Leveraging Animal Movement To Understand Spatio-Temporal Disease Dynamics, Mark Q. Wilber, Anni Yang, Raoul Boughton, Kezia R. Manlove, Ryan S. Miller, Kim M. Pepin, George Wittemyer

United States Department of Agriculture Wildlife Services: Staff Publications

The ongoing explosion of fine-resolution movement data in animal systems provides a unique opportunity to empirically quantify spatial, temporal and individual variation in transmission risk and improve our ability to forecast disease outbreaks. However, we lack a generalizable model that can leverage movement data to quantify transmission risk and how it affects pathogen invasion and persistence on heterogeneous landscapes. We developed a flexible model ‘Movement-driven modelling of spatio-temporal infection risk’ (MoveSTIR) that leverages diverse data on animal movement to derive metrics of direct and indirect contact by decomposing transmission into constituent processes of contact formation and duration and pathogen deposition …


Large- And Small-Scale Climate Influences Spring Migration Departure Probability Of American White Pelicans, D. Tommy King, Guiming Wang, Fred L. Cunningham Jan 2022

Large- And Small-Scale Climate Influences Spring Migration Departure Probability Of American White Pelicans, D. Tommy King, Guiming Wang, Fred L. Cunningham

United States Department of Agriculture Wildlife Services: Staff Publications

Endogenous (e.g., age and sex) and exogenous (e.g., climate and resource availability) factors influence avian migration phenology. However, little is known regarding the migration ecology of birds at the non-breeding grounds, including the American white pelican (Pelecanus erythrorhynchos). We used Global Positioning System transmitters to track the movements and migration of 51 pelicans from 2002 to 2012. We used the Kaplan–Meier model to estimate pelican spring migration probabilities to quantify partial migration with 94 spring migration events and used the Cox proportional hazards model to evaluate the effects of the North Atlantic Oscillation index (NAOI), Southern Oscillation Index (SOI), and …


Adaptive Risk-Based Targeted Surveillance For Foreign Animal Diseases At The Wildlife-Livestock Interface, Ryan S. Miller, Sarah N. Bevins, Gericke Cook, Ross Free, Kim M. Pepin, Thomas Gidlewski, Vienna Brown Jan 2022

Adaptive Risk-Based Targeted Surveillance For Foreign Animal Diseases At The Wildlife-Livestock Interface, Ryan S. Miller, Sarah N. Bevins, Gericke Cook, Ross Free, Kim M. Pepin, Thomas Gidlewski, Vienna Brown

United States Department of Agriculture Wildlife Services: Staff Publications

Animal disease surveillance is an important component of the national veterinary infrastructure to protect animal agriculture and facilitates identification of foreign animal disease (FAD) introduction. Once introduced, pathogens shared among domestic and wild animals are especially challenging to manage due to the complex ecology of spillover and spillback. Thus, early identification of FAD in wildlife is critical to minimize outbreak severity and potential impacts on animal agriculture as well as potential impacts on wildlife and biodiversity. As a result, national surveillance and monitoring programs that include wildlife are becoming increasingly common. Designing surveillance systems in wildlife or, more importantly, at …


Evidence For Irruptive Fluctuation In Axis Deer Of Hawai‘I, Steven C. Hess, Jonathan Sprague, Jacob Muise Jan 2022

Evidence For Irruptive Fluctuation In Axis Deer Of Hawai‘I, Steven C. Hess, Jonathan Sprague, Jacob Muise

United States Department of Agriculture Wildlife Services: Staff Publications

Axis deer on the Hawaiian Islands of Maui, Lāna‘i, and Moloka‘i simultaneously experienced one of the most dramatic population crashes on record in 2020-2021, which coincided with extended drought conditions and prompted an emergency declaration for these islands. This phenomenon has been anecdotally documented during previous drought events in 2011-2012, but never formally studied. Newspaper articles document abundant deer becoming a nuisance to agriculture and natural resources, and then experiencing high mortality during droughts. This phenomenon fits Caughley’s (1970) operational definition of eruptive (sic) fluctuation “…as an increase in numbers over at least two generations, followed by a marked decline.” …


Cultivation Of Industrial Hemp On And Near Airports: Implications For Wildlife Use And Risk To Aviation Safety, Bradley F. Blackwell, Page E. Klug, Lee A. Humberg, Zachary T. Brym, Bryan M. Kluever, Jenna Edwards Jan 2022

Cultivation Of Industrial Hemp On And Near Airports: Implications For Wildlife Use And Risk To Aviation Safety, Bradley F. Blackwell, Page E. Klug, Lee A. Humberg, Zachary T. Brym, Bryan M. Kluever, Jenna Edwards

United States Department of Agriculture Wildlife Services: Staff Publications

Industrial hemp (Cannabis sativa L.; hemp) is an emerging crop in the United States with little known about bird use or the potential for birds to become an agricultural pest. We identified birds associated with hemp fields, using repeated visits to oilseed plots in North Dakota, USA (n = 6) and cannabinoid (CBD) plots in Florida, USA (n = 4) from August to November 2020. We did not control for plot area or density; our observations were descriptive only. We observed 10 species in hemp, 12 species flying over hemp, and 11 species both foraging in and …


Industrial Hemp As A Resource For Birds In Agroecosystems: Human-Wildlife Conflict Or Conservation Opportunity?, Emily A. Kotten, Iona Hennessy, Bryan M. Kluever, Bradley F. Blackwell, Lee A. Humberg, Page E. Klug Jan 2022

Industrial Hemp As A Resource For Birds In Agroecosystems: Human-Wildlife Conflict Or Conservation Opportunity?, Emily A. Kotten, Iona Hennessy, Bryan M. Kluever, Bradley F. Blackwell, Lee A. Humberg, Page E. Klug

United States Department of Agriculture Wildlife Services: Staff Publications

Industrial hemp (Cannabis sativa L.; hemp) is an emerging crop in the United States with little known about bird use or the potential for birds to become an agricultural pest. We identified birds associated with hemp fields, using repeated visits to oilseed plots in North Dakota, USA (n = 6) and cannabinoid (CBD) plots in Florida, USA (n = 4) from August to November 2020. We did not control for plot area or density; our observations were descriptive only. We observed 10 species in hemp, 12 species flying over hemp, and 11 species both foraging in and …


Investigating How Bat Ectoparasites Influence The Skin Microbiome Diversity And Composition In Washington State Bats, Dana E. Colley Jan 2022

Investigating How Bat Ectoparasites Influence The Skin Microbiome Diversity And Composition In Washington State Bats, Dana E. Colley

EWU Masters Thesis Collection

White-Nose Syndrome (WNS), caused by the psychrophilic pathogenic fungus Pseudogymnoascus destructans (Pd), has killed millions of bats in the eastern United States since its initial introduction in 2006 and recent expansion into the western U.S. Understanding factors that contribute to the spread of Pd and risk of infection is crucial for management of WNS. Bat ectoparasites, including bat mites and bat flies, are omnipresent in bat populations, yet the relationship between these ectoparasites and bat health is still unknown. We examined the relationship between bat ectoparasites and the skin microbiome in relation to WNS infection risk in Washington State bats. …


The Role Of The Skin Microbiome In Amphibian Pathogen Susceptibility In Turnbull National Wildlife Refuge, Krista S. Dodd Jan 2022

The Role Of The Skin Microbiome In Amphibian Pathogen Susceptibility In Turnbull National Wildlife Refuge, Krista S. Dodd

EWU Masters Thesis Collection

The fungal pathogen, Batrachochytrium dendrobatidis (Bd), has led to the decline and extinction of many amphibian populations, but some bacteria in the skin microbiome can inhibit its growth. In Turnbull National Wildlife Refuge (TNWR) in eastern Washington, Bd is highly prevalent, but the role of the skin microbiome in Bd infection dynamics have not been examined in this region. We hypothesized that frogs with lower Bd infection intensities would have higher skin bacterial diversity and more abundant anti-Bd bacteria, indicative of a more protective function. Our study combined cultureindependent and culture-dependent methods to assess the relationship between Bd and the …


Analysis Of Covid-19 Pandemic Disease Metrics In Nebraska Counties With Large Meat Processing Plants, Nyah D. Chambers, James Lawler Md,Mph, Sara Donovan Mph Jan 2022

Analysis Of Covid-19 Pandemic Disease Metrics In Nebraska Counties With Large Meat Processing Plants, Nyah D. Chambers, James Lawler Md,Mph, Sara Donovan Mph

Posters: 2022 Summer Undergraduate Research Program

This poster analyzes COVID-19 disease metrics of counties with large meat processing facilities to counties with small or no meat processing facilities based on different time frames of the COVID-19 pandemic.


Novel Molecular Approaches To Diagnostic And Epidemiological Analyses Of Cryptosporidiumspp.Implicated In Clinical Infection, Jennifer K. O'Leary Jan 2022

Novel Molecular Approaches To Diagnostic And Epidemiological Analyses Of Cryptosporidiumspp.Implicated In Clinical Infection, Jennifer K. O'Leary

Theses

Cryptosporidium remains an underestimated, yet highly prevalent, parasitic agent of gastrointestinal illness worldwide. In clinical settings, diagnosis has previously relied on microscopic techniques. However, enteric parasite targeting molecular tools, such as real-time PCR panels, have superseded microscopy in recent years. This body of work examines the nature, implications and opportunities of this paradigm shift. This thesis is divided into seven chapters that consist of a literature review chapter, five experimental chapters focusing on the molecular diagnosis and epidemiological analysis of Cryptosporidium spp., and a final summary chapter. Chapter I provides the contextual narrative and supportive reasoning behind the research undertaken …


Microbial Contamination And Metabolite Exposure Assessment During Waste And Recyclable Material Collection, Fabiola Salambaga, Loïc Wingert, Isabelle Valois, Nancy Lacombe, François Gouin, Julien Trépanier, Maximilien Debia, Ewelina Soszczyńska, Magdalena Twarużek, Robert Kosicki, Marta Dias, Susana Viegas, Liliana Caetano, Carla Viegas, Geneviève Marchand Jan 2022

Microbial Contamination And Metabolite Exposure Assessment During Waste And Recyclable Material Collection, Fabiola Salambaga, Loïc Wingert, Isabelle Valois, Nancy Lacombe, François Gouin, Julien Trépanier, Maximilien Debia, Ewelina Soszczyńska, Magdalena Twarużek, Robert Kosicki, Marta Dias, Susana Viegas, Liliana Caetano, Carla Viegas, Geneviève Marchand

Études primaires

Waste workers are exposed to bioaerosols when handling, lifting and dumping garbage. Bioaerosol exposure has been linked to health problems such as asthma, airway irritant symptoms, infectious, gastrointestinal and skin diseases, and cancer. Our objective was to characterize the exposure of urban collectors and drivers to inhalable bioaerosols and to measured the cytotoxic effect of air samples in order to evaluate their health risk.

Personal and ambient air sampling were conducted during the summer of 2019. Workers from 12 waste trucks collecting recyclables, organic waste or compost were evaluated. Bacteria and fungi were cultured, molecular biology methods were used to …


The Law, Economics, And Governance Of Generation Covid-19 Long-Haul, Julia Puaschunder, Martin Gelter Jan 2022

The Law, Economics, And Governance Of Generation Covid-19 Long-Haul, Julia Puaschunder, Martin Gelter

Faculty Scholarship

The SARS-CoV-2 novel coronavirus is an external shock to all societies with lasting impacts that have changed individual, political, and corporate decisions profoundly. Increasing evidence reveals that an estimated 10-50% of those previously infected with COVID-19 face a longer-term or long-term health impact and/or chronic debilitation that in many cases comes and goes in waves. This phenomenon has already been referred to as a pandemic within the pandemic. The broad-based and long-term impact of COVID Long Haulers have also holds the potential to change our world and modern society, lasting through the following three outlined speculative trends: (1) The coronavirus …


Pet Imaging Reveals Reduced Synaptic Density In People With Well-Controlled Hiv Infection, Julian Joseph Weiss Jan 2022

Pet Imaging Reveals Reduced Synaptic Density In People With Well-Controlled Hiv Infection, Julian Joseph Weiss

Yale Medicine Thesis Digital Library

Background: Synaptic injury is a pathological hallmark of neurological impairment in people living with HIV (PLWH), a common complication despite viral suppression with antiretroviral therapy (ART). However, there are no biomarkers sensitive to neurocognitive impairment in PLWH. Measurement of synaptic density in living humans may allow better understanding of HIV neuropathogenesis and provide a dynamic biomarker for therapeutic studies. We applied novel synaptic vesical protein 2A (SV2A) positron emission tomographic (PET) imaging to investigate synaptic density in the frontostriatalthalamic region in PLWH and HIV-uninfected (HIV-) participants.

Methods: In this cross-sectional pilot study,13 older male PLWH on ART underwent neurocognitive assessments, …