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2022

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Jail Health And Early Release Practices, Brandon L. Garrett, Deniz Ariturk, Jessica Carda-Auten, David L. Rosen Jan 2022

Jail Health And Early Release Practices, Brandon L. Garrett, Deniz Ariturk, Jessica Carda-Auten, David L. Rosen

Faculty Scholarship

Local jails in the United States incarcerate millions of people each year. The COVID-19 pandemic made jail health a pressing public health concern nationally, where releasing individuals from jails occurred across the country in order to prevent pandemic spread. But releases also faced substantial resistance and exposed long-standing challenges in delivering adequate healthcare in jail settings. People in jail have substantially higher levels of medical need than individuals in the general population, with large numbers having serious mental illnesses and substance use disorders. Further, overcrowded conditions and poor healthcare standards and delivery make jails harmful to those already-vulnerable people. What …

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Machine Learning Techniques For Predicting Depression And Anxiety In Pregnant And Postpartum Women During The Covid-19 Pandemic: A Cross-Sectional Regional Study, Radwan Qasrawi, Malak Amro, Stephanny Vicunapolo, Diala Abu Al-Halawa, Hazem Agha, Rania Abu Seir, Maha Hoteit, Reem Hoteit, Sabika Allehdan, Nouf Behzad, Khlood Bookari, Majid Alkhalaf, Haleama Al-Sabbah, Eman Badran, Reema Tayyem Jan 2022

Machine Learning Techniques For Predicting Depression And Anxiety In Pregnant And Postpartum Women During The Covid-19 Pandemic: A Cross-Sectional Regional Study, Radwan Qasrawi, Malak Amro, Stephanny Vicunapolo, Diala Abu Al-Halawa, Hazem Agha, Rania Abu Seir, Maha Hoteit, Reem Hoteit, Sabika Allehdan, Nouf Behzad, Khlood Bookari, Majid Alkhalaf, Haleama Al-Sabbah, Eman Badran, Reema Tayyem

All Works

Background: Maternal depression and anxiety are significant public health concerns that play an important role in the health and well-being of mothers and children. The COVID-19 pandemic, the consequential lockdowns and related safety restrictions worldwide negatively affected the mental health of pregnant and postpartum women. Methods: This regional study aimed to develop a machine learning (ML) model for the prediction of maternal depression and anxiety. The study used a dataset collected from five Arab countries during the COVID-19 pandemic between July to December 2020. The population sample included 3569 women (1939 pregnant and 1630 postpartum) from five countries (Jordan, Palestine, …

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A Novel Tunicate Swarm Algorithm With Hybrid Deep Learning Enabled Attack Detection For Secure Iot Environment, Fatma Taher, Mohamed Elhoseny, Mohammed K. Hassan, Ibrahim M. El-Hasnony Jan 2022

A Novel Tunicate Swarm Algorithm With Hybrid Deep Learning Enabled Attack Detection For Secure Iot Environment, Fatma Taher, Mohamed Elhoseny, Mohammed K. Hassan, Ibrahim M. El-Hasnony

All Works

No abstract provided.

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The Combination Of Tlr7/8 And Tlr4 Adjuvants In An Influenza Vaccine Produce Unique Antigen-Specific Adaptive Immunity And Protect Against Lethal Heterologous Influenza Challenge, Shelby Lynn Cole Jan 2022

The Combination Of Tlr7/8 And Tlr4 Adjuvants In An Influenza Vaccine Produce Unique Antigen-Specific Adaptive Immunity And Protect Against Lethal Heterologous Influenza Challenge, Shelby Lynn Cole

Graduate Student Theses, Dissertations, & Professional Papers

Influenza virus infection is a global health concern resulting in death and illness each year, which disproportionally effects high-risk individuals. While there are several approved vaccines for seasonal influenza, there are some limitations to consider: current vaccines provide minimal cross protection against seasonally drifted influenza subtypes, influenza vaccine strains change each year, requiring timely manufacture of a new vaccine. Thus, vaccines capable of inducing a more robust and broadly protective immune response to multiple influenza subtypes remains a critical unmet need. Adjuvants and novel delivery systems are an interesting and promising avenue of exploration for enhancing and broadening seasonal influenza …

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Isolated Splenic Infarction: An Initial Manifestation Of Postoperative Atrial Fibrillation., Chaitra Janga, Kimberley Okoyeze, Vincent Chan Jan 2022

Isolated Splenic Infarction: An Initial Manifestation Of Postoperative Atrial Fibrillation., Chaitra Janga, Kimberley Okoyeze, Vincent Chan

Division of Internal Medicine Faculty Papers & Presentations

Splenic infarction is an uncommon cause of abdominal pain. In this article, we present a case of isolated splenic infarction presenting with severe abdominal pain, nausea, and with associated generalized weakness. Computed tomography (CT) abdomen and pelvis with contrast revealed multiple splenic infarctions of the entire lower pole with occlusion of the branch splenic arteries, while CT abdomen without contrast was unremarkable. Etiology was later revealed to be thromboembolism secondary to atrial fibrillation. It was managed with anticoagulation. To our knowledge, this is the second case of splenic infarction presenting as an initial manifestation of atrial fibrillation (AF), reported in …

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Hierarchy And Responsibility In Media: Cults, Culpability, And Culture, Max Hargett Jan 2022

Hierarchy And Responsibility In Media: Cults, Culpability, And Culture, Max Hargett

Online Theses and Dissertations

This is a descriptive research project that investigates how popular entertainment media portrays cults. My intention is to see how the selected films and television shows portray issues of hierarchy and culpability within the cult and to explore how the genre and theme of the content was utilized in order to evoke certain reactions and sentiments in the audience. The selected films were The Sacrament, Martha Marcy May Marlene, and Midsommar. The selected television shows were Waco and American Horror Story: Cult. Each film and series is given its own analysis. Findings indicate that a common theme of the rigid …

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Vampire Narratives: Looking At Queer-Centric Experiences In Comparison To Hetero-Centric Norms In Order To Model A New Queer Vampiric Experience, Marah Heikkila Jan 2022

Vampire Narratives: Looking At Queer-Centric Experiences In Comparison To Hetero-Centric Norms In Order To Model A New Queer Vampiric Experience, Marah Heikkila

Master's Theses and Doctoral Dissertations

This thesis examines vampire narratives such as Twilight, The Vampire Diaries, True Blood, From Dusk Till Dawn, The Gilda Stories, and Fledgling using queer and sexuality studies frameworks to look at salient patterns in the texts. The project focuses on how gender performances take place in the text, what the performances mean, and what the implications of them are. In addition to gender performance, in the thesis, I also look at how vampire narratives influence and transform binaries related to gender and sexuality. Furthermore, while popular narratives such as Twilight are fan favorites, there are …

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From Dna Logic Gates To Dna Nanorobots, Tatiana Molden Jan 2022

From Dna Logic Gates To Dna Nanorobots, Tatiana Molden

Electronic Theses and Dissertations, 2020-2023

Due to their biocompatibility and parallel data processing, DNA computational devices are highly desired for applications in diagnosis and treatment of cancer, infectious and genetic diseases. Much like in modern electronic devices, DNA computation is based on the logic gates - by directly interacting with DNA or RNA input molecules, they produce a specific output depending on their embedded logic function. This work is devoted to the development of functional parts of a future DNA nanorobot for biomedical applications. Specifically, we used DNA nanotechnology and the concept of multicomponent DNA probes to develop three parts of the DNA nanorobot: computing, …

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Exploration Of The Oral Microbiome In Non-Ventilated Hospitalized Patients, Kimberly Emery Jan 2022

Exploration Of The Oral Microbiome In Non-Ventilated Hospitalized Patients, Kimberly Emery

Electronic Theses and Dissertations, 2020-2023

Non-ventilator hospital acquired pneumonia (NV-HAP) impacts 1 in 100 hospitalized patients and is a significant patient concern due to its negative clinical outcomes. Many factors play a role in NV-HAP development: oral health, oral care, microaspiration risk, and the oral microbiome. Little is known about how the oral microbiome alters during hospitalization. This study explored changes in the oral microbiome of non-ventilated hospitalized patients over time and analyzed the relationship between the oral microbiome, pre-hospital residence, and NV-HAP. A prospective, observational design was used to recruit 46 non-ventilated adults 65 years and older from a large medical center in central …

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Return Visit Characteristics Of Sars-Cov-2 Pcr-Positive Cases In A Pediatric Emergency Department, Ni̇han Şik, Durgül Özdemi̇r, Murat Duman Jan 2022

Return Visit Characteristics Of Sars-Cov-2 Pcr-Positive Cases In A Pediatric Emergency Department, Ni̇han Şik, Durgül Özdemi̇r, Murat Duman

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to evaluate return visits to the pediatric emergency department (ED) for children who were detected to be positive for SARS-CoV-2 by polymerase chain reaction (PCR). Materials and methods: Between April 2, 2020, and January 20, 2021, children aged 0 to 18 years who were detected to be SARS-CoV-2 PCR-positive and discharged from the ED were evaluated. Among them, patients who returned to the ED within 14 days of quarantine were included in the study. For the first presentation and return visit, demographics, clinical findings, laboratory and radiologic investigations, and ward/pediatric intensive care unit …

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The Role Of Cd8+ Regulatory T Cells And B Cell Subsets In Patients With Covid-19, Hülya Uçaryilmaz, Di̇lek Ergün, Hüsametti̇n Vatansev, Hande Köksal, Onur Ural, Uğur Arslan, Hasi̇be Artaç Jan 2022

The Role Of Cd8+ Regulatory T Cells And B Cell Subsets In Patients With Covid-19, Hülya Uçaryilmaz, Di̇lek Ergün, Hüsametti̇n Vatansev, Hande Köksal, Onur Ural, Uğur Arslan, Hasi̇be Artaç

Turkish Journal of Medical Sciences

Background/aim: Coronavirus disease 2019 (COVID-19) has a wide clinical spectrum from asymptomatic to mild, moderate, and severe cases. There are still many unknowns about the role of immunoregulatory mechanisms in COVID-19. We aimed to study regulatory T cells (Tregs) and B cell subsets and evaluate their correlations with severity of COVID-19. Materials and methods: In total, 50 patients with COVID-19 confirmed by PCR (mean age = 49.9 ± 12.8 years) and 40 healthy control (mean age = 47.9 ± 14.7 years) were included in this study. The patients were classified as 14 mild (median age = 35.5 [24-73] years), 22 …

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Extinction And Growth On An Inhomogeneous Seascape, Tung Tran, Mehran Kardar Jan 2022

Extinction And Growth On An Inhomogeneous Seascape, Tung Tran, Mehran Kardar

Turkish Journal of Physics

The effects of noise and nonuniformity on dynamics of populations are relevant and timely subjects of investigation. One form of variation is the time dependence of the reproduction rate (fitness), referred to as ?seascape? noise; another is time-independent intrinsic dependencies of fitness on location (in the parlance of statistical physics, corresponding to annealed and quenched disorder, respectively). The former was studied recently and demonstrated to lead to novel universality classes for extinction and growth. To reduce the gap between this theoretical model and reality, we develop a new formalism for seascape noise where growth and migration parameters are inhomogeneous. In …

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A Comparison Of Antibody Response In Kidney Transplant Recipients And Healthcare Workers Who Had Pcr-Confirmed Covid-19 Infection, Mevlüt Tamer Di̇ncer, Necmi̇ Eren, Ahmet Murt, Nuri̇ye Yildiz, Şeyda Gül Özcan, Meti̇n Ergül, Si̇bel Gökçay Bek, Zeynep Atli, Si̇nan Trabulus, Erkan Dervi̇şoğlu, Hamdi̇ Levent Doğanay, Nurhan Seyahi̇ Jan 2022

A Comparison Of Antibody Response In Kidney Transplant Recipients And Healthcare Workers Who Had Pcr-Confirmed Covid-19 Infection, Mevlüt Tamer Di̇ncer, Necmi̇ Eren, Ahmet Murt, Nuri̇ye Yildiz, Şeyda Gül Özcan, Meti̇n Ergül, Si̇bel Gökçay Bek, Zeynep Atli, Si̇nan Trabulus, Erkan Dervi̇şoğlu, Hamdi̇ Levent Doğanay, Nurhan Seyahi̇

Turkish Journal of Medical Sciences

Background/aim: Data on antibody response following COVID-19 in kidney transplant recipients is scarce. This crosssectional study aims to investigate the antibody response to COVID-19 among kidney transplant recipients. Materials and methods: We recruited 46 kidney transplant recipients with RT-PCR-confirmed COVID-19 and 45 recipients without COVID-19 history. We also constructed two control groups (COVID-19 positive and negative) from a historical cohort of healthcare workers. We used age and sex-based propensity score matching to select the eligible subjects to the control groups. We measured the SARS-CoV-2 IgG levels quantitatively using the Abbott ARCHITECT system. An antibody level above 1.4 S/C was defined …

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Covid-19 In Pediatric Nephrology Centers In Turkey, Emre Leventoğlu, Yeşi̇m Özdemi̇r Ati̇kel, Hülya Nalçacioğlu, İsmai̇l Dursun, Hasan Dursun, Zeynep Nagehan Yürük Yildirim, Nurdan Yildiz, Gülşah Kaya Aksoy, Mehmet Taşdemi̇r, Mehtap Çelakil, Belti̇nge Demi̇rci̇oğlu Kiliç, Şenay Zirhli Selçuk, Nur Canpolat, Evri̇m Kargin Çakici, Sare Gülfem Özlü Jan 2022

Covid-19 In Pediatric Nephrology Centers In Turkey, Emre Leventoğlu, Yeşi̇m Özdemi̇r Ati̇kel, Hülya Nalçacioğlu, İsmai̇l Dursun, Hasan Dursun, Zeynep Nagehan Yürük Yildirim, Nurdan Yildiz, Gülşah Kaya Aksoy, Mehmet Taşdemi̇r, Mehtap Çelakil, Belti̇nge Demi̇rci̇oğlu Kiliç, Şenay Zirhli Selçuk, Nur Canpolat, Evri̇m Kargin Çakici, Sare Gülfem Özlü

Turkish Journal of Medical Sciences

Background/aim: There is limited data on COVID-19 disease in children with kidney disease. We aimed to investigate the characteristics and prognosis of COVID-19 in pediatric nephrology patients in Turkey. Materials and methods: This was a national, multicenter, retrospective cohort study based on an online survey evaluating the data between 11th March 2020 and 11th March 2021 as an initial step of a detailed pediatric nephrology COVID-19 registry. Results: Two hundred and three patients (89 girls and 114 boys) were diagnosed with COVID-19. One-third of these patients (36.9%) were between 10-15 years old. Half of the patients were on kidney replacement …

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Synthesis And Antimicrobial Studies Of Nano-Copper Doped Carbon Substrates; Activated Carbon, Reduced Graphene Oxide, And Carbon Nanofiber, Songwuit Chanthee, Jenjira Jirasangthong, Channarong Asasvatesanupap, Malee Santikunaporn Jan 2022

Synthesis And Antimicrobial Studies Of Nano-Copper Doped Carbon Substrates; Activated Carbon, Reduced Graphene Oxide, And Carbon Nanofiber, Songwuit Chanthee, Jenjira Jirasangthong, Channarong Asasvatesanupap, Malee Santikunaporn

Journal of Metals, Materials and Minerals

Copper oxides (CuxO) have received considerable attention as a result of their biological activity. Nanoparticles (NPs) of CuxO attached to different substrates exhibit a wide spectrum of antimicrobial activity against bacteria and viruses, with similar properties to silver. The antimicrobial activity of CuxO-NPs doped on distinctive carbon materials was investigated for three carbon substrates: apricot stone activated carbon (AAC), reduced graphene oxide (rGO) and carbon nanofiber (CNF). The CuxO-NPs (5 wt%) doped AAC and rGO substrates were prepared by impregnation of copper nitrate followed by a thermal treatment process, while a similar weight of CuxO-NPs doped CNF was fabricated by …

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Advancing Positive Water Rights, Allyson E. Gold, Srinivas Parinandi, Allen Slater, Tyler Garrett Jan 2022

Advancing Positive Water Rights, Allyson E. Gold, Srinivas Parinandi, Allen Slater, Tyler Garrett

Maryland Law Review

No abstract provided.

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The Impact Of Tobacco Use On Covid-19 Outcomes: A Systematic Review, Jessica Baker, Nandita Krishnan, Lorien C. Abroms, Carla J. Berg Jan 2022

The Impact Of Tobacco Use On Covid-19 Outcomes: A Systematic Review, Jessica Baker, Nandita Krishnan, Lorien C. Abroms, Carla J. Berg

GW Authored Works

Introduction. Tobacco use increases risks for numerous diseases, including respiratory illnesses. We examined the literature to determine whether a history of tobacco use increases risks for adverse outcomes among COVID-19 patients. Methods. We conducted a systematic search of PubMed, LitCovid, Scopus, and Europe PMC (for preprints) using COVID-19 and tobacco-related terms. We included studies of human subjects with lab-confirmed COVID-19 infections that examined tobacco use history as an exposure and used multivariable analyses. The data was collected between March 31st, 2020, and February 20th, 2021. Outcomes included mortality, hospitalization, ICU admission, mechanical ventilation, and illness severity. Results. Among the 39 …

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The Value Of A Longitudinal Human Immunodeficiency Virus Track For Medical Students: 10-Year Program Evaluation, Jasmine R. Marcelin, Paul Brosnihan, Susan Swindells, Nada A. Fadul, Sara Bares Jan 2022

The Value Of A Longitudinal Human Immunodeficiency Virus Track For Medical Students: 10-Year Program Evaluation, Jasmine R. Marcelin, Paul Brosnihan, Susan Swindells, Nada A. Fadul, Sara Bares

Journal Articles: Infectious Diseases

We surveyed graduates of a longitudinal medical school human immunodeficiency virus curriculum to evaluate its impact. Respondents felt comfortable caring for people with human immunodeficiency virus (PWH) and found value from the curriculum regardless of ultimate career path. Programs like this contribute to the development of culturally sensitive clinicians comfortable caring for PWH.

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Caregiver Willingness To Give Tpt To Children Living With Drug-Resistant Tb Patients, V. Rouzier, M. Murrill, S. Kim, L. Naini, J. Shenje, E. Mitchell, M. Raesi, M. Lourens, A. Mendoza, F. Conradie, N. Suryavanshi, M. Hughes, S. Shah, G. Churchyard, Susan Swindells, A. Hesseling, A. Gupta Jan 2022

Caregiver Willingness To Give Tpt To Children Living With Drug-Resistant Tb Patients, V. Rouzier, M. Murrill, S. Kim, L. Naini, J. Shenje, E. Mitchell, M. Raesi, M. Lourens, A. Mendoza, F. Conradie, N. Suryavanshi, M. Hughes, S. Shah, G. Churchyard, Susan Swindells, A. Hesseling, A. Gupta

Journal Articles: Infectious Diseases

Pediatric household contacts (HHCs) of patients with multidrug-resistant TB (MDR-TB) are at high risk of infection and active disease. Evidence of caregiver willingness to give MDR-TB preventive therapy (TPT) to children is limited.METHODS This was a cross-sectional study of HHCs of patients with MDR-TB to assess caregiver willingness to give TPT to children aged <13 years.RESULTS Of 743 adult and adolescent HHCs, 299 reported caring for children aged <13 years of age. The median caregiver age was 35 years (IQR 27-48); 75% were women. Among caregivers, 89% were willing to give children MDR TPT. In unadjusted analyses, increased willingness was associated with TB-related knowledge (OR 5.1, 95% CI 2.3-11.3), belief that one can die of MDR-TB (OR 5.2, 95% CI 1.2-23.4), concern for MDR-TB transmission to child (OR 4.5, 95% CI 1.6-12.4), confidence in properly taking TPT (OR 4.5, 95% CI 1.6-12.6), comfort telling family about TPT (OR 5.5, 95% CI 2.1-14.3), and willingness to take TPT oneself (OR 35.1, 95% CI 11.0-112.8).CONCLUSIONS A high percentage of caregivers living with MDR- or rifampicin-resistant TB patients were willing to give children a hypothetical MDR TPT. These results provide important evidence for the potential uptake of …

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Mitochondrial Redox Environments Predict Sensorimotor Brain-Behavior Dynamics In Adults With Hiv., Rachel K. Spooner, Brittany K. Taylor, Iman M. Ahmad, Kelsey Dyball, Katy Emanuel, Jennifer O'Neill, Maureen Kubat, Susan Swindells, Howard S. Fox, Sara Bares, Kelly L. Stauch, Matthew C. Zimmerman, Tony W. Wilson Jan 2022

Mitochondrial Redox Environments Predict Sensorimotor Brain-Behavior Dynamics In Adults With Hiv., Rachel K. Spooner, Brittany K. Taylor, Iman M. Ahmad, Kelsey Dyball, Katy Emanuel, Jennifer O'Neill, Maureen Kubat, Susan Swindells, Howard S. Fox, Sara Bares, Kelly L. Stauch, Matthew C. Zimmerman, Tony W. Wilson

Journal Articles: Infectious Diseases

Despite virologic suppression, people living with HIV (PLWH) remain at risk for developing cognitive impairment, with aberrations in motor control being a predominant symptom leading to functional dependencies in later life. While the neuroanatomical bases of motor dysfunction have recently been illuminated, the underlying molecular processes remain poorly understood. Herein, we evaluate the predictive capacity of the mitochondrial redox environment on sensorimotor brain-behavior dynamics in 40 virally-suppressed PLWH and 40 demographically-matched controls using structural equation modeling. We used state-of-the-art approaches, including Seahorse Analyzer of mitochondrial function, electron paramagnetic resonance spectroscopy to measure superoxide levels, antioxidant activity assays and dynamic magnetoencephalographic …

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The Effect Of Resource Scarcity On Consumer Ethical Behavior, Todd C. Haderlie Jr, Jaehoon Lee Jan 2022

The Effect Of Resource Scarcity On Consumer Ethical Behavior, Todd C. Haderlie Jr, Jaehoon Lee

AMTP Proceedings 2022

We identify a novel relationship between scarcity and ethical behavior. When resource scarcity is made salient, consumers engage in less ethical behavior. Furthermore, the effect of resource scarcity on ethical behavior is stronger for consumers with high (vs. low) levels of the inclusion of others in the self (IOS).

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Extremophilic Fungi From Marine Environments: Underexplored Sources Of Antitumor, Anti-Infective And Other Biologically Active Agents, Lesley Ann Giddings, David J. Newman Jan 2022

Extremophilic Fungi From Marine Environments: Underexplored Sources Of Antitumor, Anti-Infective And Other Biologically Active Agents, Lesley Ann Giddings, David J. Newman

Chemistry: Faculty Publications

Marine environments are underexplored terrains containing fungi that produce a diversity of natural products given unique environmental pressures and nutrients. While bacteria are commonly the most studied microorganism for natural products in the marine world, marine fungi are also abundant but remain an untapped source of bioactive metabolites. Given that their terrestrial counterparts have been a source of many blockbuster antitumor agents and anti-infectives, including camptothecin, the penicillins, and cyclosporin A, marine fungi also have the potential to produce new chemical scaffolds as leads to potential drugs. Fungi are more phylogenetically diverse than bacteria and have larger genomes that contain …

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Childhood Nephrolithiasis And Nephrocalcinosis Caused By Metabolic Diseases And Renal Tubulopathy: A Retrospective Study From 2 Tertiary Centers, Jameela A. Kari, Mohamed A. Shalaby, Faiza A. Qari, Amr S. Albanna, Khalid A. Alhasan Jan 2022

Childhood Nephrolithiasis And Nephrocalcinosis Caused By Metabolic Diseases And Renal Tubulopathy: A Retrospective Study From 2 Tertiary Centers, Jameela A. Kari, Mohamed A. Shalaby, Faiza A. Qari, Amr S. Albanna, Khalid A. Alhasan

Saudi Medical Journal

Objectives: To study childhood nephrolithiasis and nephrocalcinosis caused by metabolic disorders, distal renal tubular acidosis (dRTA), and familial hypomagnesemia, hypercalciuria, and nephrocalcinosis (FHHNC). Methods: We retrospectively evaluated 86 children presented over 10 years (2011-2021), with nephrolithiasis (89%) and nephrocalcinosis (11%) caused by metabolic disorders (62%), FHHNC (21%), and dRTA (17%). Results: The mean age at discovery was 72.7 months. The underlying metabolic etiologies included hyperoxaluria (38%), cystinuria (32%), hypercalciuria (24%), and hyperuricosuria (6%). Genetic testing was carried out for 23 patients. Hyperoxaluria was typically treated medically (75%). However, the majority progressed to end-stage kidney disease (ESKD). Most children with cystinuria, …

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Covid-19 Collaborative Modelling For Policy Response In The Philippines, Malaysia And Vietnam, Angus Hughes, Romain Ragonnet, Pavithra Jayasundara, Hoang-Anh Ngo, Elvira P. De Lara-Tuprio, Ma. Regina Justina Estuar, Timothy Robin Y. Teng, Law Kian Boon, Kalaiarasu M. Peariasamy, Zhuo-Lin Chong, Izzuna Mudla M. Ghazali, Greg J. Fox, Thu-Anh Nguyen, Linh-Vi Le, Milinda Abayawardana B. Eng, David Shipman, Emma S. Mcbryde, Michael T. Meehan, Jamie M. Caldwell, James M. Trauer Jan 2022

Covid-19 Collaborative Modelling For Policy Response In The Philippines, Malaysia And Vietnam, Angus Hughes, Romain Ragonnet, Pavithra Jayasundara, Hoang-Anh Ngo, Elvira P. De Lara-Tuprio, Ma. Regina Justina Estuar, Timothy Robin Y. Teng, Law Kian Boon, Kalaiarasu M. Peariasamy, Zhuo-Lin Chong, Izzuna Mudla M. Ghazali, Greg J. Fox, Thu-Anh Nguyen, Linh-Vi Le, Milinda Abayawardana B. Eng, David Shipman, Emma S. Mcbryde, Michael T. Meehan, Jamie M. Caldwell, James M. Trauer

Mathematics Faculty Publications

Mathematical models that capture COVID-19 dynamics have supported public health responses and policy development since the beginning of the pandemic, yet there is limited discourse to describe features of an optimal modelling platform to support policy decisions or how modellers and policy makers have engaged with each other. Here, we outline how we used a modelling software platform to support public health decision making for the COVID-19 response in the Western Pacific Region (WPR) countries of the Philippines, Malaysia and Viet Nam. This perspective describes an approach to support evidence-based public health decisions and policy, which may help inform other …

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Functionalized Nanomaterials As Tailored Theranostics, Kavini M. Rathnayake Jan 2022

Functionalized Nanomaterials As Tailored Theranostics, Kavini M. Rathnayake

Dissertations

Theranostic nanoparticles are a type of biodegradable and biocompatible multifunctional nanosystems in combination with diagnostic and therapeutic capabilities for more specific and personalized disease management. However, difficulties still exist in engineering biocompatible theranostic nanoparticles with highly specific to intracellular bacteria and tumor. Development of nanoassemblies which can overcome these difficulties to achieve maximum therapeutic efficacy of the drugs will be discussed in this dissertation. Pseudomonas aeruginosa (PA) is an opportunistic pathogen, which causes serious lung infections in immunocompromised patients. Traditional oral intake of large quantities of small-molecule antibiotics to treat bacterial infections leads to off-target toxicity and development of drug-resistant …

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Simplification Of Intake Process Leads To Better Understanding During Community Center Programming, George Crickard Iv Jan 2022

Simplification Of Intake Process Leads To Better Understanding During Community Center Programming, George Crickard Iv

OTD DEx Reports - College of Pharmacy and Health Sciences

"The simplification of the intake process at a community justice center will allow for a smoother transition into programming and treatment for clients. The Community Justice Support Center (CJSC) in Springfield, MA is a programming center that helps its clientele achieve the quality of life that they want while they are going through the criminal justice system. The CJSC decided that the intake process was confusing and not engaging. This project was focused on the improvement of the intake process so that participants would be more engaged in the program This engagement will lead to the client having a better …

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The Efficacy Of Online Video-Based Continuing Education Courses, Jessica Winter Jan 2022

The Efficacy Of Online Video-Based Continuing Education Courses, Jessica Winter

OTD DEx Reports - College of Pharmacy and Health Sciences

"Currently nursing professionals including home health aides, certified nursing assistants, licensed practical nurses, and registered nurses have a varied amount of continuing education (CE) requirements to maintain licensure or certification. CE requirements range from zero to fifteen contact hours every two years (Commonwealth of Massachusetts, 2022). Providing continuing education, professional development, and empowerment to health care professionals can promote improved patient care and services (Eslamian, Moeini, & Soleimani, 2015). Using an online learning method to provide continuing education can allow flexibility in the learning process, increase participant self-efficacy, and improve participant confidence. Additionally, asynchronous online CE courses can reach a …

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An Examination Of Three Transitional Events In The Substance Misuse Trajectories Of Women With Criminal Legal System Involvement, Martha Tillson Jan 2022

An Examination Of Three Transitional Events In The Substance Misuse Trajectories Of Women With Criminal Legal System Involvement, Martha Tillson

Theses and Dissertations--Sociology

Research has consistently demonstrated that criminal legal system (CLS)-involved women are distinct from men in initiation and course of drug use, with important differences on biological, environmental, and sociocultural levels. Thus, the unique pathways and transitions into and out of drug use for women with CLS involvement are critical to consider from a research perspective, but also from a need to develop and support evidence-based, women-centered services in correctional contexts. This dissertation project uses a three-paper format to investigate three aims: (1) to understand CLS-involved women’s initiations to injection drug use and their experiences providing injection initiation assistance (IIA) to …

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Can't Live With Them, Can't Live Without Them: The Impact Of Covid-19 On Funeral Homes And The Relationship Of Privacy Interests Between The Living And Decreased, Taylor A. Neeld Jan 2022

Can't Live With Them, Can't Live Without Them: The Impact Of Covid-19 On Funeral Homes And The Relationship Of Privacy Interests Between The Living And Decreased, Taylor A. Neeld

University of Dayton Law Review

No abstract provided.

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Recognizing And Addressing Conflict That Emerges From Sociotechnical Change In Higher Education, Kathleen Ann Watkins-Richardson Jan 2022

Recognizing And Addressing Conflict That Emerges From Sociotechnical Change In Higher Education, Kathleen Ann Watkins-Richardson

Department of Conflict Resolution Studies Theses and Dissertations

Today’s unprecedented technology growth impacts at many levels—from individuals to groups to society. This study aims to characterize how exponential digital technology growth and organizational change is explained and experienced in a university setting deploying new instructional technologies—and how or where conflict emerges. Organizational conflict is a phenomenon that takes many forms and may not be fully recognized. This dissertation highlights theories of technology invention and disruption, the dynamics of sociotechnical change (defined as the interdependencies between people, technology, and the environment) and response in organizations, complex adaptive systems, and practice theory of change. It considers current technological forces at …

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