Digital Commons Network^™

บทบาทพยาบาลในระบบการแพทย์ทางไกลสำหรับคัดกรอง โรคติดเชื้อไวรัสโคโรนา 2019, ดวงพร พลปัถพี

Journal of Nursing Research, Innovation, and Health

โรคติดเชื้อไวรัสโคโรนา 2019 (Coronavirus disease 2019 หรือ COVID-19) เป็นโรคติดเชื้อ ที่มีการแพร่ระบาดอยู่ในปัจจุบัน ทั่วโลกพบอุบัติการณ์การติดเชื้อและมีผู้เสียชีวิตจำนวนมาก เนื่องจากในระยะแรกผู้ติดเชื้อไม่แสดงอาการชัดเจนจึงไม่มารักษาที่โรงพยาบาล ทำให้มีการแพร่กระจายเชื้อได้ง่ายส่งผลให้อัตราการเสียชีวิตของผู้ป่วยเพิ่มมากขึ้น ดังนั้น พยาบาลซึ่งเป็นด่านหน้าในการดูแลผู้ป่วยควรมีความรู้ความเข้าใจเกี่ยวกับการคัดกรองโรค อาการแสดง การแพร่กระจายเชื้อ และบทบาทพยาบาลในระบบการแพทย์ทางไกล โดยใช้กระบวนการพยาบาลนำความรู้ภาคทฤษฎีและทักษะการพยาบาลมาประยุกต์ใช้ในสถานการณ์การแพร่ระบาดทั้งการเตรียมพร้อม การตอบสนอง และการปรับปรุงฟื้นฟูซ่อมแซม เพื่อประเมินอาการและช่วยป้องกันการแพร่กระจายเชื้อไปยังผู้รับบริการท่านอื่นและเจ้าหน้าที่ได้

The Environmental Health And Safety Leaders’ Perspectives Of Higher Education Safety Culture, Zenebe Asfir

University of the Pacific Theses and Dissertations

To safeguard the health and well-being of faculty, students, staff, and the community is of moral imperative for higher education institutions. Likewise, protecting the environment is a socially sound practice. Furthermore, building and maintaining a positive safety culture is believed to contribute to productive environmental health and safety (EH&S) outcomes. Higher education EH&S leaders are at the center of universities’ efforts in maintaining a positive safety culture. The purpose of this inquiry was to study higher education EH&S leaders’ perspectives on safety culture and contribute to closing the academic literature gap in the higher education setting. Interviews and a survey …

Do Law Enforcement Officers’ Attitudes And Knowledge Impact Their Likelihood Of Administering Naloxone?, Nicole Alexis Gulkis

PCOM Psychology Dissertations

Law enforcement officers (LEOs) are integral public service providers who have been called upon by government personnel across state and local government bodies to aid in combating the opioid epidemic. As LEOs are often the primary front-line workers who encounter opioid overdose scenarios, more states across the nation are training LEOs to administer naloxone. The emergence of Coronavirus (COVID-19) has complicated LEOs’ involvement with naloxone administration because of shifts in policing strategies and occupational safety procedures. Given the current pandemic, concerns about contraction and transmission of COVID-19 must be considered for LEOs working in the frontlines of these concurrent public …

Exploring The Association Between Female Infertility Stigma, Women’S Cognitions, And Coping Responses, Spencer Paige Brown

PCOM Psychology Dissertations

Infertility is becoming a significant problem for many women around the globe. According to the World Health Organization (WHO), infertility impacts 186 million individuals worldwide. Women who experience infertility may be exposed to increased pressure from family and friends to get pregnant, feelings of isolation, and inadequacy. Both cultural and societal views that promote the connection between womanhood and motherhood may increase a woman’s negative view about herself due to her inability to conceive a child. The purpose of this study was to bring awareness about the impact that social stigma of infertility has on a woman’s cognitions and ability …

Adoptive T-Cell Therapies To Overcome T Cell-Dependent Immune Dysregulations In Covid-19, Sevgi̇ Kalkanli Taş, Merve Sai̇de Uzunoğlu, Ayli̇n Seher Uzunoğlu, Duygu Kirkik, Derya Altunkanat, Nevi̇n Kalkanli

Turkish Journal of Biology

Coronavirus disease 2019 (COVID-19) pandemic has been an important global interest that affected millions of people, and it requires a deep investigation of the disease immunology for developing further therapeutic applications. Adoptive T cell therapy promises to address T cell-dependent immune dysregulation in COVID-19 patients by the generation of specific T cell clones against virus-specific antigens. Additionally, targeting B cell-dependent protection through COVID-19 vaccines, which have been developed in the recent year, possessed sufficient prevention for spreading the virus, since the cases and deaths related to COVID-19 tend to decrease after the vaccination. However, adoptive cell therapies are now encouraging …

Development A Novel Multi-Epitope Dna Vaccine Against Human Sars Coronavirus-2: An Immunoinformatics Designing Study, Afshin Samimi Nemati, Sako Mirzaie, Mohammad Reza Masoumian, Fatemeh Sheikhi, Mostafa Jamalan

Turkish Journal of Biology

Human SARS coronavirus 2 (SARS-CoV-2) causes the current global COVID-19 pandemic. The production of an efficient vaccine against COVID-19 is under heavy investigation. In this study, we have designed a novel multiepitope DNA vaccine against SARS-CoV-2 using reverse vaccinology and DNA vaccine approaches. Applying these strategies led to reduce the time and costs of vaccine development and also improve the immune protective characteristics of the vaccine. For this purpose, epitopes of nucleocapsid, membrane glycoprotein, and ORF8 proteins of SARS-CoV-2 chose as targets for B and T-cell receptors. Accordingly, DNA sequences of selected epitopes have optimized for protein expression in the …

Palmitic Acid Declines Glucose Uptake In Hepg2 Cells Via Modulating Phosphoglucomutase 1 To Repress Phosphatidylinositol 3 Kinase/Protein Kinase B And Jnk Pathways Via Inducing Microrna-124-3p, Linghui Zhang, Shengli Zhang

Turkish Journal of Biology

Diabetes resulting from insufficient insulin secretion or insulin resistance (IR) is a highly prevalent metabolic disease. Since microRNAs have been linked with elevated IR, the current research hypothesized that miR-124-3p has a role in IR and the establishment of IR and type 2 diabetes (T2DM). The study aimed to explore the molecular mechanisms of miR-124-3p which influence IR leading to T2DM establishment. HepG2 cells were cultured in vitro, and palmitic acid (PA) was used to construct the IR cell model. In the IR model, transfection of miR-124-3p or phosphoglucomutase 1 (PGM1) linked plasmids were transfected into HepG2 cells. RT-qPCR was …

Exploring The Behavioral Health Clinician Shortage At A Rural Midwestern U.S. Agency, Tracy L. Wilson

Walden Dissertations and Doctoral Studies

Behavioral health clinician shortages are a significant and ongoing problem in the United States, especially in rural areas, which have higher rates of homelessness, suicide, substance use, and violence rates than urban areas. The purpose of this qualitative case study was to explore factors contributing to the behavioral health clinician shortage in a rural midwestern U.S. public health department. The goal was to gain a better understanding of this shortage and explore strategies and solutions for recruiting and retaining behavioral health clinicians at the agency’s facilities. The Baldrige excellence framework undergirded the investigation. Data sources included interviews with three administrative …

Improving Patients' Engagement And Retention In Intensive Outpatient Substance Abuse Treatment, Leo W. Lavender

Walden Dissertations and Doctoral Studies

Substance use disorder continues to be a major health crisis in the United States. Thousands of people die yearly due to substance use and related criminal activity. Substance abuse treatment is a remedy to the disorder and treatment centers admit thousands of patients yearly to address the dilemma. Throughout the years retention has been an ongoing barrier to successful treatment. This study explored significant obstacles to retention: motivation and engagement. The Baldrige Excellence Framework was utilized to assess the training, supervision, procedures, and leadership roles at an intensive outpatient substance abuse treatment center. This study utilized a qualitative approach case …

Co-Parenting During Lockdown: Covid-19 And Child Custody Cases Before The Vaccine, New York Law School Family Law Quarterly Editors

Articles & Chapters

No abstract provided.

Presidential Rhetoric In Times Of Health Crises: From President Eisenhower To President Trump, Abbi Murphy, Justin Kirk

Honors Program: Senior Projects (Public)

Three major health crises in American history include the polio epidemic in the 1950s, the Ebola crisis in 2014, and the coronavirus in 2020. Each of these viruses evolved under a different President, from President Eisenhower to President Obama to President Trump. Each of these presidents spoke to the people on their respective crisis, and here I examine speeches, addresses, and social media posts in order to examine the rhetorical strategies that each President utilized. Each of them had a similar goal in mind, to eradicate the disease and quell the public’s fears. However, they all had advantages and disadvantages …

Clinical Pearls To Diagnosing Lyme Arthritis, Chandelle Keller

Capstone Showcase

Arthritis is one of the most common long term sequelae of Lyme disease infection in humans. Although the pathophysiology for Lyme arthritis is not concretely understood, there are several key features that are helpful in diagnosing Lyme disease as the culprit for the arthritic symptoms that an individual is experiencing. With a thorough history of an individuals’ age, geographic location, recent travel history and common outdoor recreational activities engaged in, a differential can be narrowed down. With the knowledge of how various arthritides present in the body, along with the use of diagnostic testing with ELISA and Western immunoblot, any …

Implementation Of Mental And Substance Misuse Screenings Into Routine Prep Therapy Encounters, Kieran Talkiewicz

Capstone Showcase

It has been well documented over the years that lesbian, gay, bisexual, transgender, queer/ questioning (LGBTQ+) populations are disproportionately affected by a higher burden of mental health illnesses, alcohol abuse, and illicit substance abuse when compared to heterosexual populations. This article will recommend utilizing routine Pre-Exposure Prophylaxis (PrEP) therapy encounters, a common point of contact for primary care for sexual minority populations, to perform screening for mental health and substance use. Due to men who have sex with men (MSM) being the highest utilizing population of this therapy, and disproportionately burdened by psychiatric and substance use disorders, this article will …

Bodily Autonomy And Anti-Vaccine Discourse During The Covid-19 Pandemic, Haley Sherman

Capstone Showcase

This paper explores the relationship between anti-vaccine discourse and ideas about bodily autonomy. I analyze the cyclical nature of vaccine hesitancy and show that it can lead to misinformation and harmful narratives. This paper uses theories of bodily autonomy that identify a concept called moral obligation. This concept, as explored by Alberto Giubilini, is a utilitarian approach in which citizens have a responsibility to their governments to get vaccinated so that, in turn, their governments can fulfill their obligation of protecting other individuals’ health (Giubilini 2020, 54). A discourse analysis of four key players in the anti-vax movement shows that …

Will Screening Women For Bacterial Vaginosis In Pregnancy Reduce The Adverse Outcomes Of Bacterial Vaginosis Infection In Pregnancy, Such As Preterm Delivery Or Low-Birth-Weight Infants?, Lauren Greiner

Capstone Showcase

Abstract

Background: Bacterial Vaginosis (BV) is a common genital tract infection in women, and in pregnant women, has been linked to adverse birth outcomes such as premature delivery and low-birth-weight infants. The treatment of BV is either Metronidazole or Clindamycin, both of which are safe during pregnancy. Currently, there are no current guidelines for screening asymptomatic women for BV while pregnant. This paper aims to analyze current literature to determine if screening asymptomatic pregnant women will reduce the outcome of preterm and low-birth-weight infants.

Methods: A literature search was completed using search terms such as “bacterial vaginosis AND screening AND …

Management Of Adult Growth Hormone Deficiency Related To Hypopituitarism, Kellie Jamin

Capstone Showcase

The treatment of growth hormone deficiency (GHD) is well-established in childhood but less understood in adults, given the more complex role that growth hormone (GH) assumes in this population. Decreased functionality of the pituitary gland, otherwise known as hypopituitarism, can present with an isolated GHD in adulthood, which may result from a number of factors including neoplasm, ischemia, infection, traumatic injury, or systemic disease. Adult GHD may be definitively diagnosed with a stimulation test, the insulin tolerance test (ITT) being the study of choice. With a positive ITT, the disorder can be treated with growth hormone replacement therapy (GHRT), which …

The Duties Of Occupying Powers In Relation To The Prevention And Control Of Contagious Diseases Through The Interplay Between International Humanitarian Law And The Right To Health, Dr. Marco Longobardo

Vanderbilt Journal of Transnational Law

This Article explores the rules governing the prevention and control of contagious diseases in occupied territory under international law. Although the Article refers to the ongoing COVID-19 pandemic, its scope is broader and encompasses instances of state practice that have occurred over the last two centuries. After a careful analysis of the relevant treaties and episodes of state practice, the Article concludes that occupying powers have duties under international humanitarian law and international human rights law to prevent and control contagious diseases, through cooperating with the local authorities and bringing the necessary medical supplies in the occupied territory. The Article …

Reducing Inappropriate Antibiotic Use, Sarah Breeden

Capstone Showcase

Inappropriate use of antibiotics is a common problem in healthcare, resulting in adverse drug reactions and the development of MDROs. Antibiotic overuse has caused a huge financial cost to society as well as a huge cost to human life and human quality of life. This article reviews common reasons for inappropriate antibiotic use and examines procalcitonin and how it can be used to reduce the burden of antibiotic overuse on society.

Simulation Of An Inflammatory Model Using Schwann Cells, Caitlyn E. Henry, Peyton Kimmel, Mackenzie Wilcox, Angela Asirvatham

SURF Posters 2022

Schwann cells are a type of glial cell in the peripheral nervous system that produce the myelin sheath surrounding neuronal axons. This myelin insulates the neurons and promotes the rapid conduction of electrical impulses throughout the body. Schwann cells have also been found to play a critical role in neuron repair following nerve injury. During nerve injury, the myelin sheath is damaged, stimulating Schwann cells to release cytokines, or inflammatory mediators, that recruit immune cells to the site of injury so that the myelin debris can be cleared, and repair can take place.1 Then neuronal growth is facilitated by heregulin …

Analyzing Behavioral Adaptation To Covid-19 And Return To Pre-Pandemic Baselines In A Cohort Of College Seniors, Vlado Vojdanovski

Computer Science Senior Theses

As the critical phase of the COVID-19 pandemic seems to be winding down, it is important to analyze the adjustment to COVID-19 and return to normalcy of various populations. In this study we focus on the behavioral adjustments exhibited by a cohort of N=114 college seniors. To infer COVID-19 adjustment we compare the 2021 year (second year of COVID-19) to the 2020 year (first year of COVID-19) and 2019 (prepandemic baseline year). We begin with a broad analysis between the second and first covid year, finding that the second year of COVID-19 shows significant returns to pre-pandemic baselines on multiple …

Does The Novel Coronavirus Use The Ocular Surface As An Entrance Into The Body Or As An Infection Site?, Remzi Karadag, Alp Kayiran, Christopher J Rapuano

Wills Eye Hospital Papers

This study attempts to review whether the coronavirus disease-2019 (COVID-19) is transmitted through the ocular surface and examine the symptoms and signs of ocular disease. Considering that COVID-19 is transmitted by airborne droplets and close contact with infected individuals, we will also review the conditions to which eye clinics and ophthalmologists should pay attention to prevent the transmission of the disease. Although some researchers have argued that COVID-19 transmission cannot occur through the ocular surface, most of them are of the opinion that the ocular surface is a potential pathway of transmission. Until date, ocular signs and symptoms have been …

Risk Of Alzheimer's Disease Following Influenza Vaccination: A Claims-Based Cohort Study Using Propensity Score Matching, Avram S Bukhbinder, Yaobin Ling, Omar Hasan, Xiaoqian Jiang, Yejin Kim, Kamal N Phelps, Rosemarie E Schmandt, Albert Amran, Ryan Coburn, Srivathsan Ramesh, Qian Xiao, Paul E Schulz

Faculty, Staff and Student Publications

BACKGROUND: Prior studies have found a reduced risk of dementia of any etiology following influenza vaccination in selected populations, including veterans and patients with serious chronic health conditions. However, the effect of influenza vaccination on Alzheimer's disease (AD) risk in a general cohort of older US adults has not been characterized.

OBJECTIVE: To compare the risk of incident AD between patients with and without prior influenza vaccination in a large US claims database.

METHODS: Deidentified claims data spanning September 1, 2009 through August 31, 2019 were used. Eligible patients were free of dementia during the 6-year look-back period and≥65 years …

Enhancing Diagnosis Through Technology: Decision Support, Artificial Intelligence, And Beyond, Robert El-Kareh, Dean F Sittig

Faculty, Staff and Student Publications

Patient care in intensive care environments is complex, time-sensitive, and data-rich, factors that make these settings particularly well-suited to clinical decision support (CDS). A wide range of CDS interventions have been used in intensive care unit environments. The field needs well-designed studies to identify the most effective CDS approaches. Evolving artificial intelligence and machine learning models may reduce information-overload and enable teams to take better advantage of the large volume of patient data available to them. It is vital to effectively integrate new CDS into clinical workflows and to align closely with the cognitive processes of frontline clinicians.

Magi1 Inhibits Interferon Signaling To Promote Influenza A Infection, Yin Wang, Jun-Ichi Abe, Khanh M Chau, Yongxing Wang, Hang Thi Vu, Loka Reddy Velatooru, Fahad Gulraiz, Masaki Imanishi, Venkata S K Samanthapudi, Minh T H Nguyen, Kyung Ae Ko, Ling-Ling Lee, Tamlyn N Thomas, Elizabeth A Olmsted-Davis, Sivareddy Kotla, Keigi Fujiwara, John P Cooke, Di Zhao, Scott E Evans, Nhat-Tu Le

Faculty, Staff and Student Publications

We have shown that membrane-associated guanylate kinase with inverted domain structure-1 (MAGI1), a scaffold protein with six PSD95/DiscLarge/ZO-1 (PDZ) domains, is involved in the regulation of endothelial cell (EC) activation and atherogenesis in mice. In addition to causing acute respiratory disease, influenza A virus (IAV) infection plays an important role in atherogenesis and triggers acute coronary syndromes and fatal myocardial infarction. Therefore, the aim of this study is to investigate the function and regulation of MAGI1 in IAV-induced EC activation. Whereas, EC infection by IAV increases MAGI1 expression, MAGI1 depletion suppresses IAV infection, suggesting that the induction of MAGI1 may …

Evolutionary Action Score Of Tp53 Analysis In Pathologically High-Risk Human Papillomavirus-Negative Head And Neck Cancer From A Phase 2 Clinical Trial: Nrg Oncology Radiation Therapy Oncology Group 0234, Chieko Michikawa, Pedro A Torres-Saavedra, Natalie L Silver, Paul M Harari, Merrill S Kies, David I Rosenthal, Quynh-Thu Le, Richard C Jordan, Dzifa Y Duose, Saradhi Mallampati, Sanchit Trivedi, Rajyalakshmi Luthra, Ignacio I Wistuba, Abdullah A Osman, Olivier Lichtarge, Robert L Foote, Upendra Parvathaneni, D Neil Hayes, Curtis R Pickering, Jeffrey N Myers

Faculty, Staff and Student Publications

PURPOSE: An evolutionary action scoring algorithm (EAp53) based on phylogenetic sequence variations stratifies patients with head and neck squamous cell carcinoma (HNSCC) bearing

METHODS AND MATERIALS: Eighty-one resection samples from patients treated surgically for stage III or IV human papillomavirus-negative HNSCC with high-risk pathologic features, who received either radiation therapy + cetuximab + cisplatin (cisplatin) or radiation therapy + cetuximab + docetaxel (docetaxel) as adjuvant treatment in a phase 2 study were subjected to

RESULTS: At a median follow-up of 9.8 years, there was a significant interaction between EAp53 group and treatment for overall survival (

CONCLUSIONS: The docetaxel arm …

Does Spaced Retrieval Therapy Help Improve Quality Of Life For Individuals With Dementia?, Simone E. Fleary

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this systematic EBM review is to determine “Does Spaced Retrieval Therapy Help Improve Quality of Life for Individuals with Dementia?”

Study Design: A systemic review of three peer-reviewed randomized controlled trials (RCT) published in English between 2016-2017.

Data Sources: All peer-reviewed articles were selected using PubMed. All articles were published in English and selected based on relevance to the clinical question. Exclusion criteria excluded studies with combined intervention methods.

Outcome Measured: Assessment of instrumental activities of daily living (IADL) was determined using the IADL task score assessed by the recruiter. Improvement of hyperphagic behavior assessed by …

Awareness And Knowledge Of Aging And Hiv-Associated Neurocognitive Disorder: Service User And Provider Perspectives And Experiences In Southern Nevada, Renato M. Liboro, Brandon Ranuschio, Sherry Bell, Jenna Despres, Trinity Puno, Aruna Sedere, Nadia Sheik Yosef, Esmeralda Villalobos, Janelle Wackens, Lianne Barnes

Psychology Faculty Research

This community report presents the findings and analysis of a survey that was part of the quantitative stage of a mixed-method Community-Based Participatory Research (CBPR) project dedicated to examine the awareness and knowledge of racially and ethnically diverse, middle-aged and older people living with HIV/AIDS, and their healthcare and service providers from Southern Nevada, on aging, brain health, HIV/AIDS, and the condition known as HIV-Associated Neurocognitive Disorder. The CBPR project was conducted in collaboration with community partners such as the LGBTQIA+ Community Center of Southern Nevada, Southern Nevada Health District’s Ryan White Program, Community Counseling Center of Southern Nevada, and …

2021 Update To The Quality Assessment And Performance Improvement Strategy, Tennessee. Division Of Tenncare.

TennCare Additional Reports

No abstract provided.

Why Anti-Racist Education Must Include Asian American History, Leanne Kang

Mid-Western Educational Researcher

This is a commentary on why anti-racist education must include Asian American history, especially in the wake of increased hate crimes against Asians and anti-Asian bullying in schools during the COVID-19 pandemic. The first half of the paper discusses the issue and how the absence of Asian American history in K-12 and teacher preparation programs plays a role in perpetuating racism against Asians in the U.S. The second half of the paper presents how I have incorporated Asian American history into a social foundations of education course through two legal cases filed by Chinese Americans: Tape v. Hurley (1885) and …

Perceptions Of Black First-Generation College Students Regarding The Impact Of Recruitment Practices At A Predominantly White Institution During The Covid-19 Pandemic, Deann Handy Walter

Electronic Theses and Dissertations

In 2020, the coronavirus disease (COVID-19) plagued the United States, becoming one of the greatest disruptions to the U.S. higher education system in history. Affecting every aspect of institution’s operations, prospective fall 2020 and beyond students were impacted greatly by the interruption of traditional college recruitment practices which would have occurred as they made their enrollment decisions. Most affected by this interruption were students of underrepresented groups. This dissertation focuses particularly on Black first-generation students and their perceptions regarding the impact of recruitment practices at a Predominantly White Institution during the COVID-19 pandemic. A qualitative study is proposed as the …