Digital Commons Network^™

Overview Of Multi-Factor Prediction Using Deep Neural Networks, Machine Learning, And Their Open-Source Software, Richard S. Segall

Faculty Publications

This chapter first provides an overview with examples of what neural networks (NN), machine learning (ML), and artificial intelligence (AI) are and their applications in biomedical and business situations. The characteristics of 29 types of neural networks are provided including their distinctive graphical illustrations. A survey of current open-source software (OSS) for neural networks, neural network software available for free trail download for limited time use, and open-source software (OSS) for machine learning (ML) are provided. Characteristics of artificial intelligence (AI) technologies for machine learning available as open source are discussed. Illustrations of applications of neural networks, machine learning, and …

Identification Of Sars-Cov-2 Main Protease Inhibitors From A Library Of Minor Cannabinoids By Biochemical Inhibition Assay And Surface Plasmon Resonance Characterized Binding Affinity, Chang Liu, Tess Puopolo, Huifang Li, Ang Cai, Navindra P. Seeram, Hang Ma

Biomedical and Pharmaceutical Sciences Faculty Publications

The replication of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is mediated by its main protease (M^pro), which is a plausible therapeutic target for coronavirus disease 2019 (COVID-19). Although numerous in silico studies reported the potential inhibitory effects of natural products including cannabis and cannabinoids on SARS-CoV-2 M^pro, their anti-M^pro activities are not well validated by biological experimental data. Herein, a library of minor cannabinoids belonging to several chemotypes including tetrahydrocannabinols, cannabidiols, cannabigerols, cannabichromenes, cannabinodiols, cannabicyclols, cannabinols, and cannabitriols was evaluated for their anti-M^pro activity using a biochemical assay. Additionally, the binding affinities …

Newsletter Winter 2022, Annette Kluck, Margaret Savoie

Newsletters of the Graduate School

No abstract provided.

Graduate Medical Education Annual Report 2021-2022, Children's Mercy Kansas City

GME Annual Reports

Annual report of the Children's Mercy Hospital Graduate Medical Education department, including pediatric residency, internal medicine/pediatrics residency, fellowship programs, medical students, continuing medical education, and library services.

Arginine Catabolism And Polyamine Biosynthesis Pathway Disparities Within Francisella Tularensis Subpopulations, Yinshi Yue, Bhanwar Lal Puniya, Tomáš Helikar, Benjamin Girardo, Steven H. Hinrichs, Marilyn A. Larson

Department of Biochemistry: Faculty Publications

Francisella tularensis is a highly infectious zoonotic pathogen with as few as 10 organisms causing tularemia, a disease that is fatal if untreated. Although F. tularensis subspecies tularensis (type A) and subspecies holarctica (type B) share over 99.5% average nucleotide identity, notable differences exist in genomic organization and pathogenicity. The type A clade has been further divided into subtypes A.I and A.II, with A.I strains being recognized as some of the most virulent bacterial pathogens known. In this study, we report on major disparities that exist between the F. tularensis subpopulations in arginine catabolism and subsequent polyamine biosynthesis. The genes …

How Universal Is Universal? A Comparative Study Of Refugee Access To Health Care In France And Germany, Rosemary Mejia

Theses & ETDs

Annually, millions of asylum seekers leave their countries to seek safety from persecution, violence, and war. It is in the international community's interest for countries to establish methods to provide access to universal health care. This study examines health care access for refugees in France and Germany. Comparative analysis of these two universal health systems confirms that France and Germany are both states that provide asylum seekers and refugees with access to care, with only some limitations. Differences between these two universal health care systems did not significantly contribute to legal access to care for refugees. National policies between the …

Covid-19 And The Carceral System: An Examination Of The Increasing Structural Inequities In Access To Healthcare In Sarasota And Manatee County Jails, Danielle Robbins

Theses & ETDs

The purpose of this thesis is to examine the impact of the COVID-19 pandemic on access to healthcare in Southwest Florida jails. The ongoing public health crisis has underscored the importance of examining these constructions in a cautious yet expeditious manner. While a considerable amount of research seeks to understand COVID-19 within prisons, there is limited information that contextualizes the novel virus within jails. This thesis aims to augment existing literature by taking a closer look at public health and disease prevention in jails. This project draws on data accumulated from nine ethnographic interviews dated from December of 2021 through …

Genome Sequence Analysis Of A Novel Sediment-Derived Marine Bacterium And Its Biosynthesis Of The Antimicrobial Molecules Prodigiosin And Cycloprodigiosin, Cara Ruhnke

Theses & ETDs

With the rise of antimicrobial resistant bacteria, the search for novel compounds exhibiting antimicrobial properties has become an important area of research. Antimicrobial secondary metabolites produced by novel species of bacteria provide a new avenue for drug innovation. A red pigment-producing bacteria with antimicrobial properties was isolated from marine sediment off the coast of St. Petersburg, Florida and named MI3. The genome of MI3 showed less than 78% identity to known bacterial species. Phylogenetic analysis based on the genome showed MI3 represents a new species of the genus Zooshikella. SEM imaging showed the bacteria to be spirillum shaped and forming …

Art As Politics? How Fox News Manufactures Its Hosts’ Performances To Acquire Cable Prestige, Matthew Mcguirk

The Graduate Review

Fox News is the most popular cable news network in the United States, drawing millions of conservative viewers who trust it more than any other outlet. Although many of the network’s claims are subject to controversy or rooted in falsities, these viewers continue watching, offering a never-before-seen devotion to the network. Using Fox’s coverage of the COVID-19 pandemic, as well as insight from Karl Marx and Walter Benjamin, this paper demonstrates how Fox manufactures its hosts’ performances to advance its fetishizing of the commodity of cable prestige.

Donate Blood. Save A Life. Fact Sheet

United States Natonal Institutes of Health: Materials

Every two seconds, someone in the United States needs blood. In this two-page handout, learn about the importance of blood donation for life-saving treatments.

Socioeconomic Determinants Of Antibiotic Resistance, Kausar Jama

Theses and Graduate Projects

Background: Antibiotics were first developed to treat wounded soldiers and cases of pneumonia in World War II. By the 1940s, antibiotics became widely used to treat several infectious processes. It was not long after antibiotics were being used frequently by clinicians that resistant strains began to emerge. Today, antibiotic resistance is a growing global health concern seen in many parts of the world. There are many factors that contribute to the prevalence of antibiotic resistance.

Purpose: This paper aims to demonstrate how socioeconomic factors play a role in the development and spread of antibiotic resistance. The literature review …

Washington University Magazine, August 2022

Washington University Magazine

No abstract provided.

Washington University Magazine, December 2022

Washington University Magazine

No abstract provided.

Lowering Depression Symptoms In Adults: Exploring Nonpharmacologic/Non-Talk Therapy Based Approaches, Alyssa A. Raiolo

Theses and Graduate Projects

Background: Depression has a high prevalence, affecting more than 300 million people worldwide.1 Antidepressants and talk therapy are the current mainstays for treatment. Given the high prevalence of depression, there is value in the research regarding further treatment options.

Purpose: A literature review of studies exploring additional treatment modalities to lower depression symptoms in adults.

Methods: A comprehensive literature review was conducted using with the search terms <(adults) AND (depression, low mood, mental health) AND (pharmacologic, SSRI, SNRI) OR ( physical activity, fitness, exercise), OR (time outdoors, UV exposure, phototherapy) OR (non-talk therapy)>. Inclusion criteria were studies that were published from 2015 to the present. Exclusion criteria were studies not in English.

Conclusions: Aside from the currently recommended approaches to treating …

Integration Of Sexual Assault Nurse Examiners (Sane’S) Care Program, Erin B. Mehta

Theses and Graduate Projects

Sexual assault is a public health issue, especially for individuals experiencing homelessness, violence, and victimization. Barriers to post-sexual assault health care must be addressed to ensure individuals experiencing homelessness receive effective and adequate care. Traditionally found in Emergency Departments, Sexual Assault Nurse Examiners (SANEs) offer patient-centered, comprehensive health care to sexual assault survivors. To reduce barriers for individuals experiencing homelessness, SANEs must be accessible where health care services are utilized. Guided by Jean Watson’s Theory of Human Caring and trauma-informed principles, this project aims to embed a SANE program into a homeless-specific Midwest Health Care Center. The SANE program will …

Disability And Climate Change: A Critical Realist Model Of Climate Justice, Molly M. King, Maria A. Gregg

Sociology

Existing literature on climate change as an issue of environmental justice documents the heightened vulnerability of people with disabilities to the effects of climate change. Additionally, there are numerous studies showing that access to information is a prerequisite for perceiving risk and taking action. Building on this work, our review seeks to understand how physical disability relates to perceptions of climate-related risk and adaptations to climate-related events. We introduce a critical realist model of climate justice to understand the relationships between the environmental features that disable, risk perception and information seeking, and adaptive capacity and resilience to climate change. In …

Using Theraputic Jurisprudence To Improve Nursing Home Regulation During Future Pandemics, Kathy L. Cerminara, Alina M. Perez, Alexandra Kirby

Nova Law Review

No abstract provided.

University Of Memphis Magazine, 2020 Fall

University of Memphis Magazine

In this issue, "I Want To Go Where I Can Help" By David Waters, UofM Institute for Public Service Reporting, Illustration by Catherine Knowles

UofM alum Janice Ballard joined a group of health professionals helping fight COVID-19 in the Navajo Nation, one of the hardest hit areas in the world per capita.

Also featured, "Unearthing Ancient Egypt" by Trent Shadid

As an expert on ancient Egypt, the work of UofM history professor Suzanne Onstine is providing insight into the lives of everyday Egyptians.

Resistance And Resilience: Antibiotic Tracking To Thwart Antimicrobial Resistance, Jordan M. Fisher

Journal of Health Care Law and Policy

No abstract provided.

Reducing The Negative Effects Of Counterterrorism Frameworks And Other Restrictive Measures On Humanitarian Action And Enforcing The Obligations Of States In Relation To The Covid-19 Vaccine, Claudio Cerqueira Bastos Netto

American University International Law Review

Countering terrorism has been a priority agenda point for the international community, especially after the September 11th attacks. As the International Committee of the Red Cross (ICRC) points out, “States have had to confront a threat emanating from individuals and non-State armed groups [(NSAGs)] that resort to acts of terrorism. In response, States and international organizations have developed increasingly robust counterterrorism measures.”

The Impact Of Sickle Cell Disease On Gingival Bleeding And Oral Health Of Adults, Natalie Roa

Honors Undergraduate Theses

Oral health may serve as an indicator of overall systemic health, with each disease or condition manifesting differently in the oral cavity. Sickle cell disease (SCD) is a genetic disorder in which sickled red blood cells cause blood vessel occlusion and potentially bleeding in specific sites (e.g., gastrointestinal and intracranial bleeding). With SCD being one of the most common hereditary diseases in the world, it is essential to understand the disease and improve awareness to better treat this population. While studies have been done to evaluate the oral health of persons with SCD, few have explored the occurrence of gingival …

Clark Magazine, Winter/Spring 2022, Clark University

Clark Magazine

The Winter/Spring 2022 edition of Clark Magazine. Clark Magazine is a twice-yearly publication primarily geared towards Clark University Alumni.

The cover story is 'Mission of the Mind: The Mosakowski Institute merges psychology with technology to confront the mental health crisis devastating America's youth.'

A Fatal Case Of Ards: Concomitant Blastomycosis & Aspergillosis In An Immunocompetent Male, Hytham Rashid, Alexander Llop, Tusharkumar Pansuriya, Jayaram Turuvekere

Gulf Coast Division GME Research Day 2022

No abstract provided.

Contrast-Induced Encephalopathy Following Diagnostic Coronary Angiography, Hytham Rashid, Andrew Good, Jonathan Brown, Tusharkumar Pansuriya, Alan Fisher Covin, Mir Ali Sadat

Gulf Coast Division GME Research Day 2022

No abstract provided.

Emergency Department Use Among Probationers Enrolled In The Riverside University Health System, Whole-Person Care Pilot Program, Nirshila Chand

CGU Theses & Dissertations

Formerly incarcerated individuals suffer from poor health outcomes and often overuse emergency department (ED) services because of a lack of access to care and insurance coverage upon reentry to their community. The Riverside County Whole Person Care (WPC) pilot program implemented by Riverside University Health System (RUHS) was designed as a reentry program developed to address these challenges and ensure that releasees successfully transition back into the community. The primary aim of this project was to assess whether participating in the RUHS WPC program reduced emergency department (ED) use among recent releasees. This was a cross-sectional retrospective study of formerly …

Examining Structural Racism As A Cause Of Health Inequities Among Pacific Island Peoples In The United States And Aotearoa New Zealand: An Exploratory Comparative Case Study, Jake Ryann Cambia Sumibcay

CGU Theses & Dissertations

Native Hawaiians and Pacific Islanders (NHPI) in the United States are known to experience profound and persistent disparities across most indicators of socioeconomic status and health when compared to the majority population. Similarly, the Indigenous Māori and Pacific peoples in Aotearoa New Zealand parallel the same experiences. Reducing disparities and improving health equity among racial/ethnic minority populations have been regarded as a national priority in both the United States and New Zealand. Improved population health data have provided insights into the social determinants of health (SDoH), which has unveiled multiple factors that contribute to health disparities, including income, education, residential …

Physicians’ Perceptions Of The Utility Of Clinical Guidelines In The Management Of People With Type 2 Diabetes In Saudi Arabia, Abdulaziz Eskandarani

CGU Theses & Dissertations

Aim: The aim of this research was to assess physicians’ perception of the utility of clinical guidelines in the management of people with Type 2 diabetes in Saudi Arabia and how their perception is affected by different physicians’ characteristics and whether high perception would result in adherence to guidelines. Methods: This study employed a cross-sectional study design and used a self-administered online survey through Qualtrics software. The survey was distributed through the Saudi Society for Diabetes (SSD) whose membership includes more than five-thousand active physicians from all regions of Saudi Arabia. There were 493 respondents to the survey. Results: Around …

Post-Pandemic Outbound Travel Intentions And Preparations Of Chinese Residents: The Effects Of Media Coverage And Risk Perception, Jinhua Zhang, Rong Huang, Qian Chen, Guoqing Zhao

Plymouth Business School

No abstract provided.

A Systematic Literature Review On Humanitarian Logistics Using Network Analysis And Topic Modeling, Jin Ju Kim, Hyunmi Jang, Saeyeon Roh

Plymouth Business School

The aim of this paper is to conduct a systematic literature review to understand the research trends, identify area of improvements and recommend the future research direction in humanitarian relief logistics (HRL). Using Netminer 4.0, keyword network analysis, keyword frequency analysis, and topic modeling analysis were undertaken. As a result, it has been identified that the number of studies on HRL continuously increased since it mounted in the mid-2010s, with the main issues changing by period. Keyword network analysis and keyword frequency analysis discovered that establishment of the HRL identity and disaster response, preparation and recovery were the main issues …

Introduction Of Plasmid Dna Into Sneathia Vaginalis; The First Step To Genetic Manipulation, Rea Mansukhani, Cathyrn O'Brien, Zion Mccoy, Kimberly K. Jefferson

UROP Posters

Many bacterial pathogens are capable of secreting one or more toxins, all of which can be categorized based on their function, target, or mechanism of action. Pore-forming toxins, for instance, are characterized based on their ability to perforate the host membrane. This may result in the delivery of bacterial substances into the host cell, release of compounds from the host cell, and/or death of the host cell. Research from our lab has demonstrated that Sneathia vaginalis, a gram-negative anaerobic bacterial species that is associated with bacterial vaginosis and preterm birth, produces a pore-forming toxin referred to as cytopathogenic toxin …