Digital Commons Network^™

The Effects Of The Covid-19 Pandemic On Postgraduate Endodontic Programs In The United States, Bianca Aboubakare, James Chen, Johnah C. Galicia

Orthodontics and Endodontics Theses

In December 2019, the coronavirus disease 2019 (COVID-19) was first identified as an acute infectious disease in Wuhan, China and subsequently led to an ongoing pandemic. At the onset of the pandemic, dental professionals were understood to face the greatest exposure risk to SARS-Cov-2 due to aerosolization of fluids from the oral cavity and respiratory airways . As a result, dental professionals, including academic institutions and their students and residents halted much of their operations to minimize exposure risks and potentially slow the spread of infection to peers and patients alike. Currently, there is little in the literature that describes …

T-Lymphocyte Tyrosine Hydroxylase Regulates T H 17 T-Lymphocytes During Repeated Social Defeat Stress, Safwan K. Elkhatib, Cassandra M. Moshfegh, Gabrielle F. Watson, Adam J. Case

Journal Articles: Cellular & Integrative Physiology

Posttraumatic stress disorder (PTSD) is a debilitating psychiatric disorder which results in deleterious changes to psychological and physical health. Patients with PTSD are especially susceptible to life-threatening co-morbid inflammation-driven pathologies, such as autoimmunity, while also demonstrating increased T-helper 17 (T_H17) lymphocyte-driven inflammation. While the exact mechanism of this increased inflammation is unknown, overactivity of the sympathetic nervous system is a hallmark of PTSD. Neurotransmitters of the sympathetic nervous system (i.e., catecholamines) can alter T-lymphocyte function, which we have previously demonstrated to be partially mitochondrial redox-mediated. Furthermore, we have previously elucidated that T-lymphocytes generate their own catecholamines, and strong …

Online Sale Of Small Turtles Circumvents Public Health Regulations In The United States, Lauren E. Montague, Juliana M. Macrotrigiano, Niamh E. Keane, Hannah E. Marquardt, Jennifer A. Sevin, Nancy E. Karraker

Natural Resources Science Faculty Publications

In the United States (U.S.), pet turtles have been associated with outbreaks of salmonellosis, a serious and sometimes-fatal intestinal illness caused by Salmonella bacteria, with nearly 300,000 people being infected in some years. Children are particularly susceptible because of their propensity to put items, including small turtles, in their mouths. In 1975, a U.S. federal regulation prohibited the sale of turtles <4 inches (101.6 mm) in size, except for the purposes of export, scientific, or educational purposes. This regulation was established to reduce the incidence of salmonellosis, particularly in small children. Previous research has not evaluated the availability of turtles <4 inches in size on websites selling wildlife. We monitored 16 websites in 2021 and quantified listings of small turtles. We determined whether information on Salmonella, the 1975 federal regulation, or related state regulations were provided on the websites and determined legality of sales of small turtles by state regulations. We found that all 16 websites openly advertised and sold turtles <4 inches in size, but only half of these websites provided information about Salmonella and/or …

How Is H. Pylori Implicated In The Etiology Of Cancer?, Chaya S. Lowy

The Science Journal of the Lander College of Arts and Sciences

Gastric cancer is a major public health concern due to the many deaths it is associated with. H. pylori is present in almost all gastric cancer patients; thus, it is fundamental to understand how H. pylori is implicated in the etiology of gastric cancer. The research in this paper is primarily based on studies acquired from Touro College Online Libraries. The bacteria have the means to survive the harsh environment of the stomach by creating a safe microenvironment and propelling themselves toward safer territory. If the bacteria attach to host cells, H. pylori injects cytotoxin-associated protein A (CagA) and vacuolating …

Chapter 12: A Shared Vision For Online Teaching Effectiveness Of K-12 Steam Minority Teachers, Abeni El-Amin Ph.D., Saundra Johnson Austin

Management Faculty Publications

This chapter presents a model to improve the online teaching effectiveness of K-12 science, technology, engineering, arts, and mathematics (STEAM) educators who teach underrepresented minority (URM) students. Further, K-12 institutions must consider the imperative by creating a STEAM professional advocacy network (SPAN) through which the online teaching effectiveness of K-12 STEAM teachers is improved. Ultimately, SPAN seeks to broaden the participation of URM students in STEAM from high-need, racially diverse learning environments nationwide. There is an initiated three-phase process through SPAN that begins with a pre-launch phase to convene an advisory board. The three phases of SPAN are program implementation, …

Optimal Control And Solving Of Cellular Dna Cancer Model, Mohamed S. Mohamed, Sayed K. Elagan, Saad J. Almalki, Muteb R. Alharthi, Mohamed F. El-Badawy, Sahar A. Najati

Applied Mathematics & Information Sciences

In this study, we have presented a novel fractional numerical model for the breast cancer stages. We have proved the existence of a stable solution of the fractional model. Also, the optimal control of this model and numerical technique for the simulation of the control problem is discussed. We have proved the existence of the solution. We have achieved the results of the dissection with numeral emulations. The compartment diagram of the model is done. We have utilized Mathematica programming to calculate the outcomes. A lot of investigators have shown that bacterial DNA could generate and suck electromagnetic waves. One …

Research And Creative Activity, July 01, 2021-June 30, 2022: Major Sponsored Programs And Faculty Accomplishments In Research And Creative Activity, University Of Nebraska-Lincoln, Office Of Research And Economic Development, University Of Nebraska-Lincoln

Office of Research and Economic Development: Publications

Foreword by Bob Wilhelm, Vice Chancellor for Research and Economic Development:

This booklet highlights successes in research, scholarship and creative activity by University of Nebraska–Lincoln faculty during the fiscal year running July 1, 2021, to June 30, 2022.

It lists investigators, project titles and funding sources on major grants and sponsored awards that were active during the year; fellowships and other recognitions and honors bestowed on our faculty; books, chapters and creative literature published by faculty; performances, exhibitions and other examples of creative activity; patents and licensing agreements; and conference presentations. In recognition of the important role faculty play in …

Recombinant Ahpc Antigen From Mycobacterium Bovis Boosts Bcg-Primed Immunity In Mice, Özgün Firat Düzenli̇, Sezer Okay, İnci̇ Kazkayasi Bölük, Ayşe Fi̇li̇z Öner

Turkish Journal of Biology

Tuberculosis (TB) is still one of the most common infectious diseases around the world despite the widespread use of BCG (bacille Calmette-Guerin) strain of Mycobacterium bovis as a vaccine. This vaccine does not always protect people from TB, and, thus, new effective vaccines or vaccination strategies are being investigated. In this study, alkyl hydroperoxide reductase (AhpC) from M. bovis was evaluated as a new candidate vaccine antigen against TB in BALB/c mice model. The ahpC gene was amplified from M.bovis genome, cloned, and expressed in Escherichia coli. Vaccine antigen AhpC was formulated with Montanide ISA 61 VG, an oil-based emulsion …

Covid-19 In Sub-Saharan Africa: Monitoring Impacts On Learning Outcomes: Zambia Report, Australian Council For Educational Research (Acer), Unesco Institute For Statistics

Monitoring Learning

Six African countries participated in the COVID-19: Monitoring Impacts on Learning Outcomes (MILO) project in 2021 – Burundi, Burkina Faso, Côte d’Ivoire, Kenya, Senegal and Zambia. This report presents the key findings from the MILO project for Zambia. The MILO study was designed to provide information on the impact of the pandemic on learning outcomes. As countries work towards achieving Sustainable Development Goal (SDG) 4.1.1b, it is essential that progress towards this goal continues to be monitored. The MILO project was implemented to provide a way for countries to measure learning progress against Sustainable Development Goal (SDG) 4.1.1b prior to, …

Cauti: Are We Testing Appropriately?, Christoph Lecznar

VCU Health Nursing

Purpose: The purpose of this evidence-based quality improvement project was to decrease catheter associated urinary tract infections in a 28 bed Surgical Trauma Intensive Care Unit in a Level One Trauma Academic Medical Center.

Background: Catheter Associated Urinary Tract Infections (CAUTI) are deemed never events by the Centers for Medicare & Medicaid Services. Centers for Disease Control and Prevention estimates 17-69% of CAUTIs are preventable. Current recommendations for CAUTI reduction include: Education strategies, chlorhexidine gluconate bathing and catheter care, catheter avoidance, policies for insertion, and urine culture testing stewardship. Our unit experienced an increase in CAUTI incidence in May and …

Southern Adventist University Undergraduate Handbook 2022-2023, Southern Adventist University

Student Handbooks, Undergraduate

No abstract provided.

The Antiviral Restriction Factor Trim5 Engages Autophagy In Mitochondrial Quality Control, Bhaskar Saha, Michelle Salemi, Brett Phinney, Michael A. Mandell

Brain & Behavioral Health Research Day

The protein TRIM5α has multiple roles in anti-retroviral defense, but the mechanisms underlying TRIM5α action are unclear. Here, we used a proteomics approach to identify TRIM5α-interacting proteins. Analysis of the TRIM5α interactome found proteins participating in a wide variety of cellular functions including regulating antiviral signaling pathways. We used this data set to uncover a novel role for TRIM5α in mitophagy. Mitochondrial damage triggered the relocalization of TRIM5α to mitochondria-associated endoplasmic reticulum where TRIM5α colocalized with markers of autophagy initiation and autophagosome biogenesis. Furthermore, we found that TRIM5 was required for the recruitment of the ULK1 complex and other autophagy …

Vector Error Correction Modeling Of Covid-19 Infected Cases And Deaths, Rajarathinam Arunachalam, Tamilselvan Pakkirisamy

Journal of Statistics Applications & Probability

The main objective of this paper is to investigate the dynamic relationship between the COVID-19 infected cases and the number of deaths due to COVID-19 using the Johnsen-Fisher co-integration test, vector error correction model and Granger causality test. The daily COVID-19-infected new cases and daily deaths due to COVID-19 in the United States, Canada, Ukraine and India were collected from the website for the period from 01-04-2020 to 26-12-2010. The summary statistics revealed that the highest numbers of COVID-19-infected cases were registered in the United States, followed by India, Canada and Ukraine; the highest numbers of deaths due to COVID-19 …

Research News, Publications, 2022, Volume 4, Soumyajit Majumdar

Publications (2015-)

Publications that appeared during the period of October 1 through December 31, 2022

The Chanticleer, 2022-11-03, Coastal Carolina University

The Chanticleer Student Newspaper

The editorially independent student produced weekly newspaper of Coastal Carolina University.

Uv Exposure Causes Energy Trade-Offs Leading To Increased Chytrid Fungus Susceptibility In Green Tree Frog Larvae, Rebecca L. Cramp, Michel E. B. Ohmer, Craig E. Franklin

Faculty and Student Publications

Levels of ultraviolet (UV) radiation have increased in many parts of the world due to the anthropogenic destruction of the ozone layer. UV radiation is a potent immunosuppressant and can increase the susceptibility of animal hosts to pathogens. UV radiation can directly alter immune function via immunosuppression and photoimmunotolerance; however, UV may also influence pathogen defences by affecting the distribution of energy resources among competing physiological processes. Both defence against UV damage and repair of incurred damage, as well as the maintenance of immune defences and responding to an immune challenge, are energetically expensive. These competing demands for finite energy …

Precision Exercise Medicine: Sex Specific Differences In Immune And Cns Responses To Physical Activity, Constanza J. Cortes, Zurine De Miguel

Psychology Faculty Publications and Presentations

Physical activity is a powerful lifestyle factor capable of improving cognitive function, modifying the risk for dementia associated with neurodegeneration and possibly slowing neurodegenerative disease progression in both men and women. However, men and women show differences in the biological responses to physical activity and in the vulnerabilities to the onset, progression and outcome of neurodegenerative diseases, prompting the question of whether sex-specific regulatory mechanisms might differentially modulate the benefits of exercise on the brain. Mechanistic studies aimed to better understand how physical activity improves brain health and function suggest that the brain responds to physical exercise by overall reducing …

Towards Water Literacy: An Interdisciplinary Analysis Of Standards For Teaching And Learning About Humans And Water, Silvia‑Jessica Mostacedo‑Marasovic, Brooke Colleen Mott, Holly White, Cory T. Forbes

School of Natural Resources: Faculty Publications

Water is critical to sustain human existence. Water literacy involves understanding the interactions within and between natural and human dimensions of water systems to support informed decision-making, an important outcome for learners of all ages. It is therefore critical to foster water literacy in today’s global citizens, particularly through formal education. The purpose of this study, in tandem with a parallel study focusing on natural dimensions of water systems (Mostacedo-Marasovic et al., in press), is to examine water-related K-12 standards for teaching and learning about human dimensions of water systems to develop a comprehensive and transdisciplinary perspective on water education. …

Genome-Wide Association Study Of Disease Resilience Traits From A Natural Polymicrobial Disease Challenge Model In Pigs Identifies The Importance Of The Major Histocompatibility Complex Region, Jian Cheng, Rohan Fernando, Hao Cheng, Stephen D. Kachman, Kyusang Lim, John C.S. Harding, Michael K. Dyck, Frederic Fortin, Graham S. Plastow, Piggen Canada Research Consortium, Jack C.M. Dekkers

Department of Statistics: Faculty Publications

Infectious diseases cause tremendous financial losses in the pork industry, emphasizing the importance of disease resilience, which is the ability of an animal to maintain performance under disease. Previously, a natural polymicrobial disease challenge model was established, in which pigs were challenged in the late nursery phase by multiple pathogens to maximize expression of genetic differences in disease resilience. Genetic analysis found that performance traits in this model, including growth rate, feed and water intake, and carcass traits, as well as clinical disease phenotypes, were heritable and could be selected for to increase disease resilience of pigs. The objectives of …

2022 Annual Campus Security And Fire Safety Report, University Of Nebraska-Lincoln, University Police, University Of Nebraska-Lincoln

University of Nebraska-Lincoln, University Police

2022 Annual Campus Security and Fire Safety Report, University of Nebraska-Lincoln

Safety and security information for the University of Nebraska-Lincoln, including crime and fire statistics for the 2021 calendar year, and the information required by the Drug-Free Schools and Communities Act of 1989. All data are submitted to the United States Department of Education according to law.

Access Barriers To Long-Term Healthcare For Female Sexual Assault Survivors, Mary E. Farley

Honors Undergraduate Theses

Background: Approximately one in five women in the United States experience childhood sexual abuse or rape as an adult. Healthcare providers are often not equipped to address the long-term effects of sexual trauma and its impact on one's health. Research Question: How can healthcare providers lessen service barriers for SA survivors? Method: This qualitative study employed convenience sampling from clinics that offered family medicine, urgent care, gynecology, or obstetrics. Participants included 11 physicians, physician assistants, and nurses. A semi-structured interview guide was used to explore health providers' perspectives and current practice procedures regarding treatment for sexual assault survivors and the …

Covid-19: A Review Of Random Testing As An Augmentation Of A Close-Contact Testing Regime In Response To The Covid-19 Pandemic, John Mcdonnell

Dissertations

The COVID-19 pandemic has presented the world with a huge challenge to balance the health of the population with the scale of stringent response measures. Policy makers need evidence based recommendations to inform their response to the pandemic and the ever changing landscape it creates. Testing and isolation of infected individuals plays a critical role in containing the spread of the disease, but is aimed primarily at detecting symptomatic individuals. However, asymptomatic individuals are much more difficult to detect. This study presents the augmentation of a close contact testing regime with random testing to examine the elect on the number …

Baystate Medical Practices Annual Report - 2022, Andrew Artenstein Md, Betty Larue Rn

Baystate Medical Practices Annual Report

No abstract provided.

Dengue Virus Downregulates Tnfr1- And Tlr3-Stimulated Nf-Kb Activation By Targeting Ripk1, Darshika J. Udawatte, Diane M. Lang, Jeffrey R. Currier, Carey L. Medin, Alan L. Rothman

Cell and Molecular Biology Faculty Publications

Dengue virus (DENV) infection is the most prevalent arthropod-borne virus disease and is endemic in more than 100 countries. Several DENV proteins have been shown to target crucial human host proteins to evade innate immune responses and establish a productive infection. Here we report that the DENV NS3 protein targets RIPK1 (Receptor Interacting Protein Kinase I), a central mediator of inflammation and cell death, and decreases intracellular RIPK1 levels during DENV infection. The interaction of NS3 with RIPK1 results in the inhibition of NF-κB activation in response to TNFR or TLR3 stimulation. Also, we observed that the effects of NS3 …

Assessing The Role Of Multiple Mechanisms Increasing The Age Of Dengue Cases In Thailand, Angkana T. Huang, Saki Takahashi, Henrik Salje, Lin Wang, Bernardo Garcia-Carreras, Kathryn Anderson, Timothy Endy, Stephen Thomas, Alan L. Rothman, Chonticha Klungthong, Anthony R. Jones, Stefan Fernandez, Sopon Iamsirithaworn, Pawinee Doung-Ngern, Isabel Rodriguez-Barraquer, Derek A.T. Cummings

Cell and Molecular Biology Faculty Publications

The mean age of dengue hemorrhagic fever (DHF) cases increased considerably in Thailand from 8.1 to 24.3 y between 1981 and 2017 (mean annual increase of 0.45 y). Alternative proposed explanations for this trend, such as changes in surveillance practices, reduced mosquito–human contact, and shifts in population demographics, have different implications for global dengue epidemiology. To evaluate the contribution of each of these hypothesized mechanisms to the observed data, we developed 20 nested epidemiological models of dengue virus infection, allowing for variation over time in population demographics, infection hazards, and reporting rates. We also quantified the effect of removing or …

Covid-19, Workplace Mental Health, And The Ada "Regarded As" Prong: A Hypothetical Case Study, Matthew Saleh, Jacquelyn Thomas, Susanne Bruyere, Hannah Potter, Sarah Jane Smith

Nova Law Review

No abstract provided.

Encapsulation Of Essential Oils In Nanocarriers For Active Food Packaging, Shubham Sharma, Lilly Mulrey, Megan Byrne, Amit Jaiswal, Swarma Jaiswal

Articles

Active packaging improves a packaging system’s effectiveness by actively integrating additional components into the packaging material or the headspace around the packaging. Consumer demand and awareness have grown enough to replace chemical agents with natural active agents. Essential oils (EOs) are extensively distributed throughout nature but at low levels and sometimes with poor recovery yields, which poses an issue with their application in food. Due to the instability of EOs when added directly into a food product, they require encapsulation before being added to a packaging matrix such as liposomes, solid-lipid nanoparticles, nano-emulsions, cyclodextrins, and nanostructured lipid nano-carriers. This article …

Disparities In The Use Of Prophylactic Treatments In Reproductive Health Between The Sexes: A Recommendation For The Use Of Hpv Vaccination Schemes Rather Than Surgical Interventions To Reduce Inequities And Threats To The Public’S Health, Paul Mclaughlin

Scholarly Works

This Article will examine the unequal treatment of the sexes under the law with regard to prophylactic treatments against STDs. The second section of this Article will discuss the ethical and legal issues in the use of prophylactic treatments and the issues involving informed consent regarding their use. The third section of this Article will discuss the historic and current use of prophylactic surgeries on both sexes to prevent disease and the challenges that have been raised against such practices. The fourth section of this Article will discuss the use of the H.P.V. vaccinations in both sexes to reduce the …

A Retrospective Analysis Of Ebola Virus Disease In Liberia, Matthew Jeremiah Matson

Theses, Dissertations and Capstones

The outbreak of Ebola virus disease (EVD) centered in the West African countries of Guinea, Liberia, and Sierra Leone from 2013-2016 was the longest and largest such outbreak on record. At least 30,000 cases were reported, and the outbreak lasted nearly two-and-a-half years. Despite the progress made during and since that time, many questions remain unanswered. The studies here utilize a large set of nearly 750 whole blood samples from patients that were triaged and treated at the ELWA-3 Ebola treatment unit in Monrovia, Liberia in 2014 and 2015. Viral load, as approximated by qRT-PCR diagnostic assays in the field, …

Advancing Harm Reduction Services In The United States: The Untapped Role Of The Americans With Disabilities Act, Valarie K. Blake, Abigail Fletes, Maria Katherine Delos Reyes, John C. Messinger, Leo Beletsky

Scholarly Works

Now in its third decade, the overdose crisis continues to worsen. Harm reduction strategies, such as syringe service programs (SSPs), are proven, cost-effective responses to this ongoing public health emergency. Despite extensive research demonstrating that the health and social benefits of harm reduction services far outweigh alleged negative externalities, the number and scope of these programs continue to be severely limited. Restrictive zoning and other discriminatory legal measures figure among key barriers to harm reduction service access. The Americans with Disabilities Act (ADA) and Rehabilitation Act (RA) have recently gained prominence in challenging discrimination against people who seek substance use …