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Food And Drug Regulation: Statutory And Regulatory Supplement (2022 ), Adam I. Muchmore

Books

This Statutory and Regulatory Supplement is intended for use with its companion casebook, Food and Drug Regulation: A Statutory Approach (2021). This is not a traditional statutory supplement. Instead, it contains selected, aggressively edited provisions of the Federal Food, Drug and Cosmetic Act (FFDCA), related statutes, and the Code of Federal Regulations. The Supplement includes all provisions assigned as reading in the casebook, as well as a few additional provisions that some professors may wish to cover. The excerpts are designed to be teachable rather than comprehensive.

Do Multilingual Employees Better Adjust To Work Environment Changes? Examining The Case Of A Credit Union During The Covid-19 Pandemic, Timothy Veach, Yeongjoon Yoon, John D. Iglesias

Faculty Publications - College of Business

Purpose: Organizations have been challenged to identify antecedents to improved employee adjustment to the work environment changes that arose in the wake of the COVID-19 global pandemic. This study explores the effect of multilingualism on employee ability to adjust to workplace changes based on the concept that multilinguals have been found to switch between tasks more efficiently as compared to monolinguals. Methodology: Applying a sequential explanatory mixed methods research approach, quantitative performance evaluation data on 207 credit union employees is analyzed using hierarchical linear modeling to predict employee performance, and thematic analysis of qualitative data representing the adjustment narratives of …

The Intersection Of Traumatic Brain Injury And Homelessness, Stephanie A. Chassman

Electronic Theses and Dissertations

The rates of TBI are significantly higher among individuals experiencing homelessness compared to the general population. Up to half of individuals experiencing homelessness may have a TBI. Accurate prevalence rates of TBI among individuals experiencing homelessness are difficult to obtain due to different methods of sampling participants and differing definitions of TBI; therefore, estimates may be underrepresented. Despite past research that has examined the relationship between TBI and homelessness, there are specific gaps in knowledge such as correlates and risk factors of TBI among individuals experiencing homelessness. This three-manuscript dissertation attempts to address these gaps in knowledge.

The first manuscript …

Developing, Refining, And Testing The Intersectional Model Of Service Use: A Transgender And Nonbinary-Specific Model Of Healthcare Access, Jarrod Call

Electronic Theses and Dissertations

Transgender and nonbinary (TNB) people are more likely to experience negative health outcomes than cisgender (i.e., not TNB) people, but less likely to access healthcare services due to the systemic forces of transphobia and cisgenderism. Despite this, there are few theoretical models of healthcare access specifically designed for TNB people. This three-paper dissertation addresses this gap by developing, refining, and testing the Intersectional Model of Service Use (IMSU), a population-specific framework for researching TNB healthcare access. Manuscript one describes how the initial IMSU was developed from an integrative review of currently available TNB healthcare access literature. This initial IMSU was …

Mcops, List Of Q1 Journals (2022-2023), Faculty Members

Health collection

No abstract provided.

Response 2022, Seattle Pacific University

Seattle Pacific Alumni Magazines

No abstract provided.

Zip8-Mediated Intestinal Dysbiosis Impairs Pulmonary Host Defense Against Bacterial Pneumonia, Derrick R. Samuelson, Deandra R. Smith, Kelly C. Cunningham, Todd A. Wyatt, Sannette C. Hall, Daryl J. Murry, Yashpal S. Chhonker, Daren L. Knoell

Journal Articles: Environmental, Agricultural & Occupational Health

Pneumococcal pneumonia is a leading cause of morbidity and mortality worldwide. An increased susceptibility is due, in part, to compromised immune function. Zinc is required for proper immune function, and an insufficient dietary intake increases the risk of pneumonia. Our group was the first to reveal that the Zn transporter, ZIP8, is required for host defense. Furthermore, the gut microbiota that is essential for lung immunity is adversely impacted by a commonly occurring defective ZIP8 allele in humans. Taken together, we hypothesized that loss of the ZIP8 function would lead to intestinal dysbiosis and impaired host defense against pneumonia. To …

Surface Modification Of Biodegradable Microparticles With The Novel Host-Derived Immunostimulant Cpdi-02 Significantly Increases Short-Term And Long-Term Mucosal And Systemic Antibodies Against Encapsulated Protein Antigen In Young Naïve Mice After Respiratory Immunization, Jacob E. Parriott, Jason P. Stewart, D. David Smith, Stephen M. Curran, Christopher D. Bauer, Todd A. Wyatt, Joy A. Phillips, Elizabeth Lyden, Geoffrey M. Thiele, Joseph A. Vetro Phd

Journal Articles: Environmental, Agricultural & Occupational Health

Generating long-lived mucosal and systemic antibodies through respiratory immunization with protective antigens encapsulated in nanoscale biodegradable particles could potentially decrease or eliminate the incidence of many infectious diseases, but requires the incorporation of a suitable mucosal immunostimulant. We previously found that respiratory immunization with a model protein antigen (LPS-free OVA) encapsulated in PLGA 50:50 nanoparticles (~380 nm diameter) surface-modified with complement peptide-derived immunostimulant 02 (CPDI-02; formerly EP67) through 2 kDa PEG linkers increases mucosal and systemic OVA-specific memory T-cells with long-lived surface phenotypes in young, naïve female C57BL/6 mice. Here, we determined if respiratory immunization with LPS-free OVA encapsulated in …

Point-Of-Care Diagnosis Of Cervical Cancer: Potential Protein Biomarkersin Cervicovaginal Fluid, Büşra Köse, Özgüç Takmaz, Mete Güngör, Ahmet Tarik Baykal

Turkish Journal of Biology

Cervical cancer (CxCa) is preventable and treatable via vaccination and screening. Cervicovaginal fluid (CVF) represents the physiological components of the female genital tract. These components are suitable to be utilized for clinical purposes, therefore, making CVF a suitable material for disease screening approaches. Due to high false-negative result rates and low attendance of current expensive routine CxCa screening methods, it has become more important to develop a point-of-care (POC) screening method that every single woman could reach worldwide. For this purpose, various self-usage apparatus have been developed for screening of the human papilloma virus (HPV) infection. Furthermore, due to the …

Rethinking Constitutionally Impermissible Punishment, Nadia Banteka

Scholarly Publications

Prisons and jails endanger the health and wellbeing of incarcerated individuals and their communities. These facilities are often overcrowded and unsanitary,1 with limited access to medical care, 2 and no basic sanitation and personal hygiene products unless a person can pay the spiked prices of the jail's commissary.3 Public health emergencies compound these dangers. Most recently, the spread of the COVID-19 pandemic created a crisis for people in detention, their families, and the communities surrounding jails and prisons. For over a year, there were no vaccines against COVID-19, new strains of the virus continue to evade vaccine-induced immunity, and there …

Cas Accents, Vol. 24, No. 3 (50th Cas Foundation Anniversary Issue - Part 1), College Of Arts And Sciences, University Of The Philippines Los Baños

CAS Accents

No abstract provided.

The Effects Of Atir Blocker On The Severity Of Covid-19 In Hypertensive Inpatients And Virulence Of Sars-Cov-2 In Hypertensive Hace2 Transgenic Mice., Xiaoliang Jiang, Huadong Li, Yong Liu, Linlin Bao, Lingjun Zhan, Hong Gao, Wei Deng, Jing Xue, Jiangning Liu, Xing Liu, Junli Li, Jie Wang, Shuang Wu, Mingzhe Yan, Wei Luo, Pedro A. Jose, Chuan Qin, Xiuhong Yang, Dingyu Zhang, Zhiwei Yang

Medicine Faculty Publications

No abstract provided.

Foreword, Meera V. Patel

Annals of Health Law and Life Sciences

No abstract provided.

Table Of Contents, Annals Of Health Law & Life Sciences

Annals of Health Law and Life Sciences

No abstract provided.

Welcome To The Digital Age: Reinventing Contact Tracing And The Public Health Service Act For A Modern Pandemic Response, Michael L. Cederblom

Annals of Health Law and Life Sciences

No abstract provided.

Pandemic Response Through Whole Person Care: The Intersection Of Physical And Mental Health And The Law, Jennifer Kinsley Smith, Esq., Elizabeth J. Lattner, Ma, Allison Kreiner, Md, Edward J. Kilbane, Md, Ma, Keyvan Ravakhah, Md, Mba

Annals of Health Law and Life Sciences

No abstract provided.

Hiv-Related Shame: A Grounded Theory Study Exploring The Impact Of Psychoeducation On The Lives Of People Living With Hiv, Melissa Stuntz

DNP Research Projects

Abstract

Over the past 40 years there have been significant advances in medical care for HIV. However, many people living with HIV (PLWH) experience internalized stigma in the form of HIV-related shame. This shame has been found to negatively impact mental health, patient relationships, and adherence to healthcare. This grounded theory DNP scholarly project was aimed at developing a novel theoretical framework and practice to improve quality of life including increased viral load suppression in PLWH. To this aim, a psychoeducation curriculum based on shame resilience theory was implemented with two participants in an inner-city healthcare clinic. While the shame …

Atypical Pericardial Opportunistic Infection, Brittney Ward, David Pash, Brittney Carman

View All Washington/Montana GME

Presented at the 2022 Virtual Northwest Medical Research Symposium

Eng 300: The Efficacy Of Bacteriophage & Lysin Antimicrobials In Industrial & Commercial Settings, Bella Norman

English 100-200-300 Conference

No abstract provided.

Type I Ifn Signaling Protects Mice From Lethal Sars-Cov-2 Neuroinvasion., Md Bashir Uddin, Yuejin Liang, Shengjun Shao, Sunil Palani, Michael Mckelvey, Scott C. Weaver, Keer Sun

Journal Articles: Pathology and Microbiology

Multiple organ damage is common in patients with severe COVID-19, even though the underlying pathogenic mechanisms remain unclear. Acute viral infection typically activates type I IFN (IFN-I) signaling. The antiviral role of IFN-I is well characterized in vitro. However, our understanding of how IFN-I regulates host immune response to SARS-CoV-2 infection in vivo is incomplete. Using a human ACE2-transgenic mouse model, we show in the present study that IFN-I receptor signaling is essential for protection against the acute lethality of SARS-CoV-2 in mice. Interestingly, although IFN-I signaling limits viral replication in the lung, the primary infection site, it is dispensable …

A Training Curriculum For Retrieving, Structuring, And Aggregating Information Derived From The Biomedical Literature And Large-Scale Data Repositories, Darawan Rinchai, Damien Chaussabel

Faculty Research 2023

Background: Biomedical research over the past two decades has become data and information rich. This trend has been in large part driven by the development of systems-scale molecular profiling capabilities and by the increasingly large volume of publications contributed by the biomedical research community. It has therefore become important for early career researchers to learn to leverage this wealth of information in their own research.

Methods: Here we describe in detail a training curriculum focusing on the development of foundational skills necessary to retrieve, structure, and aggregate information available from vast stores of publicly available information. It is provided along …

Virginia Dental Journal (Vol. 99, No. 3, 2022)

Virginia Dental Journal

No abstract provided.

Graduate Catalog 2022-2023, Southwestern Oklahoma State University

Graduate Catalogs

The 2022-2023 SWOSU Graduate Catalog.

Vaccine Apartheid: A Human Rights Analysis Of Covid-19 Vaccine Inequity, Sarah Joseph, Gregory Dore

Florida State University Journal of Transnational Law & Policy

In this paper, we analyse the inequity in current global vaccine distribution through the lens of international human rights law. First, we introduce the currently available COVID-19 vaccines, before discussing causes and consequences of vaccine inequity, as well as efforts to expand global vaccine access. We then turn to explain the relevant obligations of states regarding human rights to health, life, and equitable access to the benefits of technology. In light of those obligations, we assess the human rights compatibility of vaccine procurement and vaccine aid. After a discussion of the possible human rights responsibilities of the pharmaceutical companies that …

A Nurse's Impact On Global Health Concerns, Meagan Yoder

Student Research Poster Presentations 2022

No abstract provided.

Does The Thermal Mismatch Hypothesis Predict Disease Outcomes In Different Morphs Of A Terrestrial Salamander?, Matthew Venesky, Joseph Alan Demarchi, Cari-Ann M. Hickerson, Carl D. Anthony

2022 Faculty Bibliography

Many aspects of ectotherm physiology are temperature‐dependent. The immune system of temperate‐dwelling ectothermic host species is no exception and their immune function is often downregulated in cold temperatures. Likewise, species of ectothermic pathogens experience temperature‐mediated effects on rates of transmission and/or virulence. Although seemingly straightforward, predicting the outcomes of ectothermic host−pathogen interactions is quite challenging. A recent hypothesis termed the thermal mismatch hypothesis posits that cool‐adapted host species should be most susceptible to pathogen infection during warm temperature periods whereas warm‐adapted host species should be most susceptible to pathogens during periods of cool temperatures. We explore this hypothesis using two …

Sustainable Development Matters For Animals Too: Governments Have A Responsibility To Recognize That., Jeff Sebo, Cleo Verkuijl, Maria Jose Hotzel, Ploy Achakulwisut, Mairon Baston Lima, Jonathan Green

General - Environmental Sustainability

Animals matter for sustainable development, and sustainable development matters for animals. Yet animal welfare remains largely neglected in sustainable development governance. The 2030 Agenda for Sustainable Development aims to protect species, biodiversity, and habitats, but not individual animals. This June, governments will convene for the UN Stockholm+50 Conference, which marks 50 years of international environmental decision making. At this conference, governments have an opportunity to recognize the importance of animal welfare for sustainable development, and to aspire to harm animals less and benefit them more as part of sustainable development governance. We call on governments to take these steps for …

Modernizing Medical Research To Benefit People And Animals, Jarrod Bailey, Carla Owen, Isobel Hutchinson

General - Animal Welfare

In the context of widespread public and political concern around the use of animals in research, we sought to examine the scientific, ethical, and economic arguments around the replacement of animals with New Approach Methodologies (NAMs) and to situate this within a regulatory context. We also analyzed the extent to which animal replacement aligns with British public and policymakers’ priorities and explored global progress towards this outcome. The global context is especially relevant given the international nature of regulatory guidance on the safety testing of new medicines. We used a range of evidence to analyze this area, including scientific papers; …

Operationalising One Health-One Welfare, Janice H. Cox

One Health

The World Health Organisation (WHO) describes One Health as an approach to designing and implementing programmes, policies, legislation and research in which multiple sectors communicate and work together to achieve better public health outcomes. WHO considers the ‘One Health’ approach to be “critical to addressing health threats in the animal, human and environment interface”.

On Florida Law, Language, And Alcohol Use Disorder, Stacey A. Tovino

Nova Law Review

No abstract provided.