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Developing A Semester-Long Project In A Biomechanical Engineering Course To Instill The Entrepreneurial Mindset In The Next-Generation Biomedical Engineering Students, Loren Hedgecock

Biomedical Engineering Undergraduate Honors Theses

Entrepreneurial-Minded Learning (EML) is an emerging pedagogy progressively gaining popularity in the engineering education community. Coincided with project-based learning (PBL), EML illustrates an essential dimension to the instruction of next-generation engineers, equipping them with various perspectives and approaches to relate societal challenges with technical concepts. Nationwide initiatives, such as the Kern Entrepreneurial Engineering Network (KEEN), have developed a learning framework specifically designed to create engineers such as these. The implementation of EML aims to stimulate connections, create value, and ignite curiosity. This study introduced a semester-long project based on these EML skillsets in a sophomore-level biomechanical engineering course. To evaluate …

Novel Nanocomposites For The Treatment Of Lung Infections, Uday Kumar Chintapula

Bioengineering Dissertations - Archive

Lung infections, especially lower respiratory tract infections and their associated pneumonias, are one of the leading causes of death, accounting for more than 4 million fatalities every year worldwide. Bacterial pathogens are involved in many lower respiratory tract infections including emerging antibiotic resistant respiratory pathogens such as methicillin-resistant staphylococcus aureus (MRSA). Current interventions for MRSA lung infections include systemic antibiotic treatments for an extended period leading to various side effects such as acute kidney injury, nephrotoxicity, and so on. To overcome these limitations, the goal of this dissertation research is to develop a drug delivery system, which includes pathogen-specific drug-loaded …

Industrial Construction Safety Policies And Practices With Cost Impacts In A Covid-19 Pandemic Environment: A Louisiana Dow Case Study, Brian Briggs, Carol J. Friedland, Isabelina Nahmens, Charles Berryman, Yimin Zhu

Faculty Publications

There are always significant challenges in improving the safety culture by changing and adding additional safety protocols. The unknown impacts of COVID-19 and how it quickly spreads led the industry to institute essential safety protocols. This paper addresses two problem statements. The first problem statement is: what are the additional safety protocols for process safety, construction & maintenance, and personal protective equipment requirements? The second problem statement is: what are the cost and schedule impacts of industrial construction projects resulting from implementing safety protocols and process safety during construction with the added PPE? While complying with added safety protocols, the …

Assessing The Influence Of Health Policy And Population Mobility On Covid-19 Spread In Arkansas, Tayden Barretto

Industrial Engineering Undergraduate Honors Theses

The outbreak of COVID-19 has created a major crisis across the world since its start in 2019, and its influence on every realm of society is undeniable. Globally, more than 500 million cases have been recorded since March 2020, with almost 6 million deaths. In the wake of this crisis, many governments and health organizations have taken steps and precautions to mitigate its spread. These steps involve public mandates of information, reducing frequency of personal contact, and use of masks to minimize the risk of transmission. Current access to mobility data released from Google detailing population movements has provided a …

Collegiate Football Players Perception Of The Covid-19 Virtual College Experience, Cole L. Laliberty

Leadership Education Capstones

The world was faced with chaos as the COVID-19 virus surged impacting the lives of everyone around the world. Quickly, nations and states began to lockdown as people were required to stay inside and socially distance from one another. The pandemic changed the lives of collegiate football players’ drastically. It left collegiate football players stranded away from teammates, coaches, families, and resources. The research design was a mixed method design consisting of both qualitative and quantitative data. The data obtained from this research focused on major themes of how collegiate football players perceived the pandemics virtual college experience, the challenges …

Reusable Pulse Oximeters Could Result In Significant Cost Savings And Waste Reduction, Scott Dale, Md, Matthew Owrey, Alexa Tomlak, Kathryn Bormes, Allison Weiss, John Waters

Health Equity and Quality Improvement (HEQI) Summit

The goal of this project was to evaluate whether implementing reusable pulse oximeters impacts patient care, is financially feasible, and generally supported.

Dalbavancin Utilization And Associated Clinical Outcomes Within A Large, Integrated Health System, Meagan Greckel, Brent Footer

Providence Pharmacy PGY2 Program at Providence Medical Group 2022

No abstract provided.

Evaluating The Impact Of A Pharmacist Run Pharmacotherapy Service On Hepatitis C Outcomes In A Large Integrated Health-System, Jessica Hendrix, Charmaine Hunt, Judy Perkins

Providence Pharmacy PGY1 Program at Providence Portland and Providence St. Vincent Medical Centers 2022

No abstract provided.

Evaluation Of A Beta-Lactam Antibiotic Allergy Assessment Tool For Patients Receiving Surgical Prophylaxis, Katelynn Tran, Alyssa B Christensen, Tobias Pusch, Jennifer Marfori

Providence Pharmacy PGY1 Program at Providence Portland and Providence St. Vincent Medical Centers 2022

No abstract provided.

Increasing Adherence Of Chg Bathing: An Evidence-Based Practice Quality Improvement Project, Melissa Benedetto

DNP Projects

Introduction

Patients admitted to hospitals are at risk for developing Healthcare-acquired Infections (HAIs). Evidence suggests that these infections, including Central Line Associated Infections (CLABSIs), increase the cost of patient care and have a negative impact on patient outcomes. Daily chlorhexidine (CHG) bathing has been identified to help decrease HAIs in the hospital for patients in the Intensive Care Unit (ICU), those with Multi-drug Resistant Organisms (MDROs), and/or patients with a Central Venous Catheter (CVC).

Purpose

The purpose of this project is to implement an intervention to assess and improve CHG bathing adherence for hospitalized patients. Patients targeted include those at …

Utah Tick Surveillance An Animated Public Service Announcement, Keith Wilson

Undergraduate Honors Capstone Projects

As the United States’ population grows, we develop more land into housing and recreate farther into wilderness areas, consequentially encountering ticks with increasing frequency. As the climate continues to change, tick population distributions are also changing, influencing our population’s exposure to tick-borne diseases. Lyme disease, a tick-borne disease named after Lyme, Connecticut, is one of the fastest growing emerging diseases in North America, and the most prevalent vector-borne infection in the United States. There are two species of tick in North America, Ixodes scapularis and Ixodes pacificus, known to be carriers of the causative agent of Lyme disease, a …

The Evolution And Unraveling Of The American Eugenics Movement, Anneka Walton

Undergraduate Honors Capstone Projects

While the evolution of American eugenics surrounding the time of Nazi Germany has been well-documented, the periods before the explosion of American eugenics and the result of the movement in the wake of the Holocaust are not so well known. Many historically-based works have described the path and growth of eugenics from the time the term was coined to the public acknowledgement of World War II and the point where Americans ended eugenic euthanasia and slowed eugenic sterilizations. There are also many works within the realm of disability history that document these events from the more common social viewpoint. This …

Aggregatibacter Actinomycetemcomitans Exploits And Modulates The Immune Response By Human Neutrophils For Survival In The Anaerobic Environment., Hazel Ozuna

Electronic Theses and Dissertations

Aggregatibacter actinomycetemcomitans (Aa) is a Gram-negative facultative anaerobe and an opportunistic oral pathogen, strongly associated with localized periodontitis and other inflammatory diseases. Periodontitis is a chronic inflammation of the periodontium resulting from the inflammatory response of the host towards the dysbiotic microbial community present at the gingival crevice. The host immune response creates a hostile environment for microorganisms; therefore, it is important for Aa to be able to regulate the necessary genes to survive and thrive in such an environment. Aaexpresses several virulence factors such as a cytolethal distending toxin (Cdt), lipopolysaccharide (LPS) and leukotoxin A (LtxA), …

Statistical Methods For Assessing Drug Interactions And Identifying Effect Modifiers Using Observational Data., Qian Xu

Electronic Theses and Dissertations

This dissertation consists of three projects related to causal inference based on observational data. In the first project, we propose a double robust to identify the effect modifiers and estimate optimal treatment. Observational studies differ from experimental studies in that assignment of subjects to treatments is not randomized but rather occurs due to natural mechanisms, which are usually hidden from the researchers. Many statistical methods to identify the treatment effect and select the optimal personalized treatment for experimental studies may not be suitable for observational studies any more. In this project, we propose a exible outcome model to select the …

Characterization Of Gangliosides And Fatty Acids In Extracellular Vesicles From Human Milk, Aliya Amin

Food Science (MS) Theses

Extracellular vesicles (EVs) are bioactive components of human milk that may impact functionality to regulate growth, cognitive development, metabolism, and immunity in newborns. The biogenesis of EVs and the mechanism by which EVs elicit biologic effects in vivo have not been characterized entirely. Gangliosides and fatty acids are integral in the formation, release, stability, and functionalities of EVs. Presumably, EV function is related to EV composition and lipids in EVs influence the bioavailability of EV cargo and downstream functions of EVs. The objective of this research was to characterize the fatty acid and ganglioside composition of EVs in human milk. …

2022-May-01-Research Spotlight, University Marketing And Communication, East Tennessee State University

ETSU News

JOHNSON CITY – Five East Tennessee State University scientists recently participated in an international study focused on developing new approaches to improve the effectiveness of vaccines.

Research Spotlight

Data from this multi-institutional study, “An adjuvant strategy enabled by modulation of the physical properties of microbial ligands expands antigen immunogenicity,” was published in the journal Cell.

The research focused on modulating the physical properties of fungal sugars, called mannans, to …

Leveraging Ai And Supply Chain Technologies With Thermal Imaging And Telemedicine For Early Detection And Prevention Of Covid-19 And Respiratory Infections In Urm Communities, Gohar Azeem

Industrial, Manufacturing, and Systems Engineering Dissertations - Archive

The underserved population could be at risk during the times of crisis, unless there is strong involvement from government agencies such as local and state Health departments and federal Center for Disease Control (CDC). The COVID-19 pandemic was a crisis of different proportion, creating a different type of burden on government agencies. Vulnerable communities including the elderly populations and communities of color have been especially hard hit by this pandemic. This forced these agencies to change their strategies and supply chains to support all populations receiving therapeutics. The National Science Foundation (NSF Award # 2028612) funded this research to help …

Sexually Transmitted Diseases Consultation And Education For Adolescents And Young Adults, Maryrose Chinedu Obidiaku

Nursing Dissertations - Archive

Sexually transmitted diseases (STDs) have drastically increased in recent years nationwide and worldwide. Adolescents and young adults (AYAs) ages 15-24 make up just over one-quarter of the sexually active populace. Additionally, AYAs account for half of the 20 million new sexually transmitted infections in the United States. Compared with older adults, sexually active adolescents aged 15–19 years and young adults aged 20–24 years are at higher risk of getting STDs. Lack of knowledge of risk and protective factors and high-risk sexual health practices and behaviors significantly contribute to AYAs' STD acquisition. Hence, increasing STDs awareness and prevention is essential in …

2022-05-01_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus/stats/coronavirus-symptoms. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated twice a week on Mondays and Thursdays.

Syndromic Surveillance System data is obtained from approximately 216 facilities participating in syndromic surveillance (139 Emergency Departments (ED), 77 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, …

Institute Of Public Health Newsletter- Volume3, Issue2, Institute Of Public Health (Iph)

Institute of Public Health Newsletter (IPHNL) and Other Publications

Volume 3, Issue 2 (May August 2022)

Patient Harm Associated With Illegal Online Sellers Of Covid- 19 Drug Products: A Year In Review, Kyla Rae Maloney

Undergraduate Honors Thesis Collection

As the online marketplace continues to expand, more patients are turning to the internet for their needs, including COVID-19 pharmaceuticals. However, the current online marketplace is saturated with illegal sellers offering substandard and falsified (SF) products with the potential of causing harm to patients. The primary objective of this thesis is to identify documented cases of harm resulting from illegal online sale of SF COVID-19 related drug or vaccine products. This review utilizes reports by the Medicines Quality Monitoring Globe (MQM Globe) to assess patient harm associated with illegal online sales of COVID-19 marketed pharmaceuticals. This review found 28 references …

An Exploration Of Covid-19 Impact On Healthcare Workers’ Mental Health In China, Jenny Yang

Nursing | Senior Theses

Background

In December 2019, the first confirmed human case of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or COVID-19 occurred in Wuhan, China. By March 2020, the World Health Organization (WHO) had classified the COVID-19 outbreak as a pandemic due to the rapid spread of the virus to other countries. Many people have been affected by the COVID-19 pandemic in various aspects, especially front-line healthcare workers. Hospital working conditions are constantly changing to cope with the problems that arise from the pandemic. These problems can result in an unsafe patient-to-nurse ratio, understaffed healthcare workers in hospitals, equipment shortage, and increased …

Lipid Rafts, Exosomal Vesicles And Anti-Giardial Therapies, Brian Ivan Grajeda

Open Access Theses & Dissertations

Giardia lamblia, a protozoan parasite, is a major cause of waterborne infection, worldwide. While the trophozoite form of this parasite induces pathological symptoms in the gut, the cyst forms transmit the infection via contaminated water. Since Giardia is a non-invasive parasite, the actual mechanism by which it causes infection remains elusive. We have previously reported that Giardia assembles cholesterol and GM1 glycolipid-enriched lipid rafts (LRs) that participate in encystation and cyst production. To further delineate the role of LRs in pathogenesis, we isolated LRs from Giardia and subjected them to proteomic analysis. Various cellular proteins including the virulent proteins—e.g., giardins, …

Time Course Investigation Of The Dermal Leukocyte Response To Lipoteichoic Acid In Chickens, Ian Gilbert

Animal Science Undergraduate Honors Theses

Lipoteichoic acid (LTA) is component of the cell wall of Gram-positive bacteria that stimulates inflammation during bacterial infection. However, few studies have investigated the in vivo immune response to LTA, and none of the in vivo studies done have been performed in birds. For this project, the pulp (a skin-derivative) of growing feathers (GFs) of chickens were used as a test site to investigate the in vivo effects of intradermally injected LTA. In Study 1, the pulp of 12 GFs of 11-week-old Light-brown Leghorn (LBL) males were injected with 10 μL of differing concentrations of LTA (0.1, 1.0, 10, 100 …

Misinformation And Vaccine Hesitancy Determinants: The Significance Of Framed Public Health Messaging, Alexandra I. Todd

Capstone Experience: Master of Public Health

In 2020, the SARS-CoV-2 (COVID19) outbreak effectively disrupted worldwide operation for months, leading to tremendous economic loss and adverse health outcomes. While countries grappled to control the virus and scientists worked around the clock to deliver a vaccine in record time, a pubic health communication crisis emerged. The spread of false and misleading information, also known as misinformation, has proved to be a barrier in the fight against COVID19 and its vaccination effort. Many factors including the rise of social media, distrust of government, polarization of news sources, and fragmented media have created an environment susceptible to misinformation. Utilized correctly, …

Local Public Health Legal Landscape Report, Christina Hitz

Capstone Experience: Master of Public Health

This report provides a framework for understanding and examining local public health authority and implications of proposed legislative changes, specifically whether a shift is occurring in public health authority from the executive to the legislative branch. It compares the public health governance and legal infrastructure of states making a shift in 2021 relative to Nebraska’s current and proposed public health infrastructure and provides a synopsis of the legal context for and the scope of local public health authority currently in Nebraska. Three resources were used to create two tables to compare both states with legislative changes in 2021 indicating a …

The Epidemiology Of Extended Spectrum Beta-Lactamase-Producing Enterobacterales In Nebraska, 2018 – 2021, Axel A. Vazquez Deida

Capstone Experience: Master of Public Health

Background: Extended spectrum beta-lactamase (ESBL)-producing Enterobacterales are considered a serious public health threat by the United States Centers for Disease Control and Prevention. However, surveillance of ESBL-producing Enterobacterales is currently limited to select states and the epidemiology of these antibiotic-resistant bacteria in Nebraska is still not well understood.

Objective: To describe the incidence of ESBL-producing Enterobacterales across local health department (LHD)-jurisdictions as well as at the state-level over time and assess population-specific factors associated with infection or colonization with these pathogens in Nebraska.

Methods: A retrospective, cross-sectional analysis of public health surveillance data reported to the Nebraska Department of …

A Systematic Literature Review Of The Use Of Technology As An Emergency Preparedness Tool To Control And Contain The Covid-19 Pandemic, Alyssa Spartz

Capstone Experience: Master of Public Health

Various tools and strategies have been utilized in response to the COVID-19 pandemic. In addition to preexisting measures, novel mechanisms and methods have also been developed since the COVID-19 pandemic began to address several different needs worldwide. Technology, for example, has served as a unique and multifunctional tool to aid with controlling and containing the pandemic. While studies and reviews have been conducted to analyze specific types of technology, such as digital applications, a gap in the literature currently exists that fails to comprehensively understand and compare how multiple types of technology were implemented to address the COVID-19 pandemic. This …

Housing To Health: A Literature Review Analyzing Housing Pathways And Policy Initiatives, Evan P. Lesser

Capstone Experience: Master of Public Health

Housing is a vital aspect of an individual’s ability to enjoy a healthy lifestyle. It is so integral that the United Nations has stated that housing is a human right and extends beyond just basic shelter where housing should provide a certain level of structural integrity of the infrastructure, security, affordability, and access to surrounding resources. Existing research studying the relationship between housing and health outcomes suggest those with poor housing exhibit higher levels of chronic conditions such as asthma, heart disease, and diabetes, and higher chances of accidents within the home. The goal of this literature review, which has …

The Effect Of Post-Traumatic Stress Disorder On First Responders Following A Disaster: A Literature Review, Briar Butner

Capstone Experience: Master of Public Health

First responders work in a high-stress environment that can potentially produce traumatic situations. This includes aiding in the recovery and response efforts of critical events such as a disaster. A significant risk factor for developing post-traumatic stress disorder symptoms is people who have been through a disaster (National Institute of Mental Health, 2019). This literature review aims to search for evidence on PTSD in first responders following a disaster, identify the factors associated with the development of PTSD, and make recommendations on best practices to reduce or mitigate the incidences of PTSD. The search was conducted in three academic databases: …