Digital Commons Network^™

Economic Evaluation Of Ai-Assisted Technologies In Healthcare: A Systematic Review, Wen-Tung Wu, Yi-Wen Chao, Tsung-Kun Lin, Ching-Kuo Huang, Ping-Hsuan Hsieh

Journal of Food and Drug Analysis

Artificial intelligence (AI) technologies are increasingly integrated into healthcare, yet their economic value remains uncertain. Traditional economic evaluation methods may not adequately capture the unique features of AI, including dynamic model evolution, scalability, and broader societal impacts. This systematic review synthesized existing evidence on the cost-effectiveness of AI-based healthcare interventions and assessed the methodological rigor of published studies. A comprehensive search identified health economic evaluations of AI applications published between September 2019 and March 2025, following PRISMA and SWiM guidelines and registered in PROSPERO (CRD42025641230). Eligible studies were full economic evaluations comparing AI-based interventions with non-AI alternatives, and data were …

Rewriting The Monster: Carmilla As Laura's Gothic Double And Subversive Prince Charming In Le Fanu's Queer Gothic Fairy Tale, Annalee Tanner

English Theses

Rewriting the Monster: Carmilla as Laura's Gothic Double and Subversive Prince Charming in Le Fanu's Queer Gothic Fairy Tale

Diagnostic Stewardship Considerations In Infectious Diseases, Shawn Vasoo

Asian Medical Journal and Alternative Medicine

Diagnostic stewardship in infectious diseases is crucial to ensure that the right test is performed for the right patient for the right reasons at the right time, with the right interpretation which results in the right treatment, optimizing patient care. Managing clinicians have a critical role to play in thoughtful decision making in the pre- and post-analytic phases of test selection, interpretation and subsequent action. They also need to have a good understanding of the analytic phase of testing (test performance characteristics and limitations). In this paper, diagnostic stewardship across the main testing modalities for infectious diseases (culture, serology and …

Rsv In Pediatrics: Immunization Strategies And Treatment Insights, Mike Smith, Maria Deza Leon

Pediatrics in Practice: A CME Podcast

Respiratory Syncytial Virus (RSV) remains a leading cause of hospitalization in infants and young children. In this episode, we sit down with Dr. Maria Deza Leon to explore the latest in RSV prevention and treatment. From maternal immunization and monoclonal antibodies like Nirsevimab to practical guidance on managing severe cases, we’ll cover what pediatricians need to know this season. Tune in for evidence-based strategies, emerging therapies, and tips to navigate supply and coverage challenges—helping you protect your patients and stay ahead of RSV trends.

Click here to stream the podcast episode.

Mapping Climatic And Environmental Determinants Of Parasitic Helminth Prevalence In Southeast Asia, Angelica Avisado

UNLV Theses, Dissertations, Professional Papers, and Capstones

Climate change is reshaping environmental conditions across Southeast Asia (SEA) through rising temperatures, altered precipitation patterns, and increased droughts. These changes alter transmission dynamics of neglected tropical diseases (NTDs) by shifting spatial distribution, increasing larval development rates, faster pathogen growth development, and increasing transmission rates. NTDs are a group of preventable and treatable infections that disproportionately affect more than 1 billion people globally, specifically in tropical and subtropical regions. A subgroup of NTDs, parasitic helminth infections (PHIs) - particularly schistosomiasis, soil-transmitted helminths, and lymphatic filariasis remains a public health concern in the Southeast Asian region. PHIs and their ecological responses …

Results Of The 2024 Immunization Status Survey Of 24-Month-Old Children In Tennessee, Tennessee. Department Of Health.

Immunization Rates

No abstract provided.

Editor’S Note, Thana Khawcharoenporn

Asian Medical Journal and Alternative Medicine

No abstract provided.

Impact Of Staff Education To Clinical Documentation Integrity Team, Leyna Belcher

Walden Dissertations and Doctoral Studies

The doctoral project investigates the impact of education on Clinical Documentation Integrity (CDI) nurses in enhancing the accuracy and quality of clinical documentation within healthcare organizations. Clinical documentation plays a crucial role in accurately reflecting patient care and is essential for capturing proper diagnoses, coding, and reimbursement. In contrast, inaccurate or incomplete documentation can lead to misdiagnoses, poor patient outcomes, and financial deficits. Due to frequent updates in clinical guidelines and coding standards, CDI professionals require continuous, specialized training to stay informed with ever-changing medical terminology, disease processes, and coding regulations. By enhancing the CDI education, the aim is to …

Oxytocin Varies Across The Life Course In A Sex-Specific Way In A Human Subsistence Population, Abigail E. Colby, Dominik C. Jud, Valerie Baettig, Jordan S. Martin, Camila Scaff, Michael D. Gurven, Benjamin C. Trumble, Bret A. Beheim, Paul L. Hooper, Daniel K. Cummings, Hillard Kaplan, Jonathan Stieglitz, Arnulfo Cary Ista, Adrian V. Jaeggi

ESI Publications

Oxytocin, a hormone linked to reproduction and health, may mediate life-history trade-offs across the human life course. Yet, how oxytocin naturally varies with age remains poorly understood. Here, working with the Tsimane, forager-horticulturalists of lowland Bolivia, we collected the largest sample of oxytocin measurements to date (n = 1,242 samples, n = 405 individuals, age = 2 to 84 y, 51% female), and i) examined how oxytocin varies throughout the life course in females and males, and ii) investigated potential drivers of age- and sex-specific variation. Our sample provides rare insight into the relationship between oxytocin and age in a …

The Incorporation Of Salivary Diagnostic Testing In Dental Hygiene Program Curriculum; A Pilot Study Using A Self-Reported Questionnaire, Carrie B. Palmer-Hawkins

Dental Hygiene ETDs

This study evaluated the incorporation of salivary diagnostic testing in dental hygiene program curricula. A recruitment email and survey link were sent to a convenience sample of 296 CODA-accredited program directors in the United States. Using a descriptive research approach, the survey gathered quantitative and qualitative data exploring directors’ perspectives on the role of salivary testing in dental hygiene education. Thirty-seven responses were gathered over three weeks, and 34 participants were included in the study, resulting in a response rate of 13%. Thirty-eight percent (n=13) reported incorporating salivary testing into their dental hygiene program curriculum through didactic or clinical coursework. …

Guillaume Dustan's Ethico-Politics Of The Body, Noah Mertz

Foreign Languages & Literatures ETDs

In this MA Thesis, I lay out a synthetic overview of polemical French writer Guillaume Dustan's (1965-2005) political philosophy. He is criticized first as irresponsible and dangerous for his defense of barebacking (sex without condoms) in the midst of the AIDS epidemic, and then, after his death, as a neoliberal/anarcho-capitalist for his focus on individual liberty. My overview touches on Dustan's Freudian belief that repression is the root of all social ills, his functional ethics of self-responsibility, the revaluation of heteronormative Judeo-Christian morality towards 'virtusex,' and his social contract that minimizes repression. Dustan’s goal is for you to autonomously subjectify …

Meningococcemia In Boy With Dense Deposit Disease Receiving C5 Complement Inhibitor Ravulizumab, Andrew Gonedes, Alexandra Martinez, Allan M. Greissman, Hanan Atia, Eric Boccio

Florida Journal of Emergency Medicine (FJEM)

No abstract provided.

Impact Of Patient Education Meetings On Disease Knowledge In Chronic Urticaria Patients, Nazan Beyhan, Hati̇ce Eylül Bozkurt Yilmaz, Asli Çi̇ftci̇, Ömür Aydin, Di̇lşad Mungan, Betül Ayşe Si̇n, Gülfem Eli̇f Çeli̇k, Murat Türk, İnsu Yilmaz, Sevi̇m Bavbek

Turkish Journal of Medical Sciences

Background/aim: Chronic urticaria (CU) is a manageable disease with symptoms of itching and visible lesions that can disrupt daily life and reduce quality of life. The severity of symptoms can vary, and the cause is often unknown. Concerns among patients as regards to treatment and prognosis highlight the need for disease education to enhance self-management and reduce anxiety. The present study examines the effect of disease education on the knowledge level of CU patients.

Materials and methods: Patients with CU who presented to the allergy clinics of two tertiary university hospitals were invited to inperson education sessions including slide presentations …

Psychological Capital Of Hospital Nurses In The United States During And After The Covid-19 Pandemic, Mary Jean Erschen-Cooke

Walden Dissertations and Doctoral Studies

This study was conducted to explore lived experiences, perceptions, and associated meanings reported by nurses during the COVID-19 pandemic to determine what protected their well-being. A plethora of research focused on the negative impact of exhaustion, compassion fatigue, moral distress, and burnout; however, there was a gap in information regarding supports for emotional, mental, spiritual, and physical health, particularly among U.S. nurses. The foundational theory of psychological capital (PsyCap), focusing on the positive psychological traits of hope, self-efficacy, resilience, and optimism, grounded this investigation. A basic qualitative research design yielded rich data from semistructured interviews with 16 nurses working full …

Functional Impact Of Single Nucleotide Polymorphism Rs4129009 (Ile775val) On Human Toll-Like Receptor 10, Audrey N. Koti

Biology Student Research

Toll-like receptors (TLRs) are a subclass of pattern recognition receptors within the

innate immune system that detect pathogen-associated and danger-associated molecular patterns,

thereby initiating host defense responses. The human TLR family comprises ten receptors (TLR1

– TLR10), each recognizing structurally conserved microbial motifs such as bacterial

lipoproteins and viral nucleic acids. The ligand specificities, adaptor protein recruitment, and

downstream signaling cascades have been well-characterized for TLR1 – TLR9, which

predominantly engage MyD88- or TRIF-dependent pathways to activate pro-inflammatory

transcription factors including NF-κB. In contrast, the ligand specificity and intracellular

signaling mechanisms of TLR10 have yet to be fully elucidated. Emerging …

Chinese Intellectual Property Theft On United States Innovation In The Aerospace, Energy, And Pharmaceutical Economic Sectors Through Human Intelligence And Cyber Intelligence Collection, Preston Martz

Honors Theses

In cases of Chinese intellectual property theft on aerospace, energy, and pharmaceutical sectors in the United States, does Chinese intelligence collection favor HUMINT or CYBINT for collection? Sub questions also arise, including: to what extent does the amount of information collected vary by collection through HUMINT vs. CYBINT? Furthermore, does the sector where IP theft is used change the method of collection used? Finally, to what extend do case factors and outcomes affect the collection method used?

Comparison Of The Combination Of Prp And Topical Minoxidil To Topical Minoxidil Alone On Androgenetic Alopecia, Leia Hyunyoung Son, Ashley Olivia Owens

Physician Assistant Capstones, 2020-current

Objective: To assess the efficacy of combination therapy of platelet-rich plasma (PRP) and topical 5% minoxidil compared to topical 5% minoxidil alone in androgenetic alopecia (AGA). Methods: A PubMed search using the term “PRP hair” was conducted. The following criteria were used for the search: published in the last 10 years, randomized controlled trials, clinical trials, free full text, and full text. Three articles that met these criteria were chosen for systematic review. Results: In all three studies, the combination of PRP with topical 5% minoxidil had increased hair density and higher patient satisfaction compared to topical minoxidil alone. Conclusion: …

Treating Atopic Dermatitis: Oral Jak1 Inhibitor Vs. Monoclonal Antibody, Abby Craft, Nicolle Holgate

Physician Assistant Capstones, 2020-current

Objective: To compare symptom management of atopic dermatitis between injectable monoclonal antibodies and an oral Janus kinase 1 (JAK1) inhibitor. Design: Literature review. Methods: Searches were done in PubMed and CINAHL using the following terms: abrocitinib, Cibinqo, dupilumab, Dupixent, and atopic dermatitis. Filters included: randomized controlled trials, clinical trials, and scholarly journal. Results: Three studies met all criteria including Bieber et al, Reich et al, and Huang et al. Conclusion: Oral JAK1 inhibitor abrocitinib has been shown to have similar efficacy in symptom management of moderate-to-severe atopic dermatitis compared to monoclonal antibody dupilumab and should be considered when prescribing treatment.

Sex Disparities In Prescription Opioids Associated Cardiovascular Adverse Events, Li Ma

Theses and Dissertations

The opioid crisis in the United States has evolved from a medical response to pain into a nationwide public health emergency. The prescription opioids (POs) – associated cardiovascular adverse events (CVAEs) remain insufficiently studied, especially in relation to sex disparities. This dissertation investigates sex disparities in PO-associated cardiovascular adverse events (CVAEs) through an analytic framework integrating artificial-intelligence-assisted literature mining and real-world pharmacovigilance analytics. In the analytic framework, first, AI powered topic modeling was employed to uncover POs-associated CVAEs risks with a focus on sex differences. A total of 1,837 PubMed abstracts were analyzed using two methods, Latent Dirichlet Allocation (LDA) …

The Cytotoxicity And Anti-Inflammatory Properties Of 1’S-1’-Acetoxychavicol Acetate (Aca) On Oral Cells, Nur Umairah Atiqah Sabri, Nor Syazwani Muhammad Zahidan, Zulfahmi Said, Siti Noor Adnalizawati Adnan, Normaliza Ab Malik

Journal of Dentistry Indonesia

Objective: Mouthwash is widely used to maintain oral health by reducing the prevalence of pathogenic microbiomes. Nonetheless, chlorhexidine, a common active ingredient, is associated with side effects including teeth staining, mucosal peeling, mouth and tongue numbness. This has prompted interest in natural alternatives. This study aimed to identify the cytotoxicity and anti-inflammatory properties of 1’S-1’-acetoxychavicol acetate (ACA) isolated from Alpinia conchigera rhizome against human primary gingival fibroblast and keratinocyte (HPGF and HPGK). Methods: Cytotoxicity of ACA (1.57 mg/mL) against HPGF and HPGK was assessed using the MTT assay. Meanwhile, the anti-inflammatory property of ACA was analyzed based on …

Antibacterial Analysis Of Human Amniotic Membrane Against Streptococcus Mutants, Streptococcus Sobrinus, And Enterococcus Faecalis, Mohamad Ezany Yusoff, Ruhil Hayati Hamdan, Haslina Taib, Tan Li Peng, Maizan Mohamed, Rumaizi Shaari, Mohamad Arif Awang Nawi

Journal of Dentistry Indonesia

Objectives: The human amniotic membrane (HAM) is a promising scaffold for oral applications due to its antimicrobial properties, which help protect against bacterial degradation. However, evidence of its activity against oral bacteria remains limited. Thus, this study aimed to evaluate the antibacterial activity of the HAM against selected Gram-positive oral bacteria, namely, Streptococcus mutans (S. mutans), Streptococcus sobrinus (S. sobrinus), and Enterococcus faecalis (E. faecalis). Methods: HAM in 1 cm²-pieces was inoculated with bacterial suspensions and incubated at 37 °C in 5% carbon dioxide (CO₂) for 48 hours to evaluate …

Factors Influencing The Re-Emergence Of Vaccine-Preventable Diseases Using The Social Ecological Model: A Scoping Review, Glenda Dorina Rodriguez Lenarduzzi

Master's Projects and Capstones

Abstract

Background.

Several factors contribute to the resurgence of vaccine-preventable diseases, affecting coverage rates and vaccine uptake during recent outbreaks. The pandemic has underscored how crucial it is to comprehend vaccine literacy, as this understanding influences people's perspectives and behaviors toward vaccination, particularly in their approaches to problem-solving and decision-making.

Objective.

The present study conducts a scoping review of research on the impact of vaccine literacy and vaccine uptake on the re-emergence of vaccine-preventable diseases in the United States, framed by the social ecological model (SEM).

Design.

PubMed and Google Scholar were utilized as online databases to identify papers published …

Reducing Hospital-Acquired Pressure Injuries Through Targeted Nurse Education On The Braden Scale And Skins Bundle, Sarah Nicole Farkas

Master's Projects and Capstones

Objective: Hospital-acquired pressure injuries (HAPIs) continue to rise nationally despite overall reductions in other hospital-acquired conditions. This project sought to address gaps in nurse knowledge, inconsistent prevention practices, and workflow barriers contributing to HAPI development on a Trauma Medical-Surgical Unit (Unit A). Aim: This project aims to decrease the number of HAPIs on the Trauma Medical Surgical Unit by 11%, from nine HAPIs to eight HAPIs, following implementation of nurse education on the proper use of the Braden Scale and the SKINS Bundle from October 6, 2025, to November 14, 2025. Methods: A pre-intervention survey was administered to identify baseline …

A Quality Improvement Initiative To Streamline Flu Vaccine Documentation And Increase Staff Engagement, Carla E. Giron

Master's Projects and Capstones

Objective: This quality improvement project was implemented in an urban community health clinic primarily serving low-income and Latinx patients. Factors such as demographics, socioeconomic status, health, and transportation contribute to low U.S. influenza vaccination rates (Chen et al., 2020), while EHR training can improve provider satisfaction and efficiency (DiAngi et al., 2019). This microsystem faced inconsistent workflow processes, limited EHR training, and documentation errors that contributed to low staff satisfaction rates and influenza vaccination rates. An average of 11.4% of patients received a flu vaccine in October 2023 and 2024. Medical assistants (MAs) completed a pre-intervention survey indicating that 35% …

Spatiotemporal Ecology Of Mycobacterium Ulcerans And Mycolactone Functions In French Guiana And Southeastern United States Aquatic Environments, Magdalene Dogbe

Theses and Dissertations

Mycobacterium ulcerans, the causative agent of Buruli ulcer, produces mycolactone, a polyketide toxin traditionally studied for its role in human pathogenesis. This dissertation presents a comprehensive spatiotemporal analysis of M. ulcerans and mycolactone producing mycobacteria (MPM) ecology in the Americas and also reveals mycolactone's role in the environment as a microbial community regulator. Through comparative studies in French Guiana (endemic) and the southeastern United States (non-endemic), combined with experimental microcosm investigations, this research contributes to environmental pathogen ecology understanding. Environmental surveillance across 2,226 samples from French Guiana revealed complete MPM restriction to freshwater environments, with zero detections from 1,226 coastal …

Toward A Unified Network Flow Framework: From Conservation Principles To Fluid Dynamics Models, Zonghan Zhang

Theses and Dissertations

Network flows govern a wide range of critical systems, from tangible infrastructures like transportation and power grids to replicable processes such as information spread and epidemics. While tangible flows obey conservation laws and physical constraints, replicable flows, like rumors or viruses, can grow, decay, or vanish unpredictably. Despite their increasing interaction in real-world settings, these flow types are typically modeled in isolation, using disconnected mathematical frameworks. This dissertation presents a unified modeling approach that bridges the gap between conserved and replicable flows by embedding principles from fluid dynamics into graph-based propagation models. I introduce physically informed extensions to classical models, …

2022u_Nhp60_Approved_Nc_Phlt-1013-Introduction-To-Public-Health, Undergraduate Curriculum Council

All Approved Curriculum

No abstract provided.

2023g_Approved_Agri053_Nc_Drvm_7363_Equine_Medicine_&_Surgery_Ii, Graduate Council

All Approved Curriculum

No abstract provided.

2023g_Approved_Agri052_Nc_Drvm_7353_Equine_Medicine_&_Surgery_I, Graduate Council

All Approved Curriculum

No abstract provided.

2023g_Approved_Agri015_Nc_Drvm_716v_Veterinary_Immunology, Graduate Council

All Approved Curriculum

No abstract provided.