Digital Commons Network^™

Salivary Immunity Of Elite Collegiate American Football Players Infected With Sars-Cov-2 Normalizes Following Isolation, Joshua Granger, Eunhan Cho, Kevin Lindsey, Nathan Lemoine, Derek Calvert, Jack Marucci, Shelly Mullenix, Hollis O’Neal, Brian A. Irving, Neil Johannsen, Guillaume Spielmann

School of Medicine Faculty Publications

The impact of COVID-19 on systemic immunity in the general population has been well characterized, however the short-term effects of COVID-19 infection on innate salivary immunity in elite-level athletes are unknown. Therefore, this study aimed to determine whether elite college football athletes had altered salivary immunity following the CDC-recommended isolation post-SARS-CoV-2 infection. Salivary samples were obtained from fourteen elite football players who tested positive for SARS-CoV-2 (n = 14), immediately after CDC-recommended isolation (average days = 14 ± 2 days) and fifteen controls who remained uninfected with SARS-CoV-2. Biomarkers of innate salivary immunity (sIgA and alpha-amylase), antimicrobial proteins (AMPs, i.e., …

Fulbright Grantees Selected, Keith Testa

UNH Today Archive

No abstract provided.

Impact Of Hospital Inventory Management Of Ppe On State-Level Healthcare Worker Infections During The Covid-19 Pandemic, Nidhal Bouazizi

College of Business Theses and Dissertations

The COVID-19 pandemic has put a spotlight on the personal protective equipment (PPE) supply chain and its inability to keep up with the fluctuating demands of a global pandemic. Limited research examines the resilience of the PPE supply chain in times of stress, and very few studies rely on quantitative retrospective analysis. This dissertation studies the impact of hospital inventory management, a portion of PPE supply chain preparedness, on infections in healthcare workers (HCWs). Our research shows that there exists a statistically significant negative relationship between PPE preparedness and infections for HCWs, but this relationship is only significant for N95 …

American Contagions: Epidemics And The Law From Smallpox To Covid-19 By John Fabian Witt, Stephanie Cho

Osgoode Hall Law Journal

At the time of writing, the coronavirus known as COVID-19 has swept across the world and affected nearly every aspect of daily life as we know it. Canada has had approximately 20 thousand deaths and about 780 thousand total cases and the United States has had over 400 thousand deaths and more than 25 million total cases.

Global Health Electives In The Covid-19 Era: Resuming Travel And Strengthening Global Health Academic Partnerships., Heather Haq, Amos Msekandiana, Mogomotsi Matshaba, Linoeo Thahane, Jennifer Watts, Reena Tam, Nicole St Clair, Charles Schubert, Amy Rule, Pia Pannaraj, Michael Pitt, David Oleson, Brittany Murray, Lee Morris, Joanne Mendoza, Megan Mchenry, Elizabeth Keating, Kathy Ferrer, Heather Crouse, Tania Condurache, Maneesh Batra, Adelaide Barnes, James Conway

Manuscripts, Articles, Book Chapters and Other Papers

No abstract provided.

Provision Of Mental Health Care To Healthcare Workers During Covid-19: A Call For The Practice Of Vulnerability, J Hoare

Peninsula Medical School

No abstract provided.

Parens Patriae, Punishment, And Pandemics: The State’S Responsibility For Incarcerated Persons During A Public Health Emergency, Meredith Harrell

Journal of Law and Health

This article looks at the nation’s response to the COVID-19 pandemic since March 2020 and explores the commonalities and differences of states’ actions to protect their citizens, especially the most vulnerable populations. The article discusses the government’s obligations to jailees and prisoners during the COVID-19 pandemic and how incarcerated persons have been consistently failed by the institutions that are required to protect them. The article examines possible remedies for these governmental and institutional failings under the Eighth Amendment and § 1983 civil rights claims. Ultimately the article proposes that monetary damages would provide relief to incarcerated individuals and their families …

Fragmentation Drives Dominant Plant Encroachment On A Horizontal Wastewater Treatment Levee, Joia S. Fishman

Master's Theses

Urban coastal wetlands protect humans from sea-level rise while providing valuable habitat for wildlife. Degradation and loss of these wetlands threaten urban infrastructure such as wastewater treatment facilities. Nature-based adaptive solutions with the combined purposes of bioremediation, coastal defense, and habitat creation are being tested to make communities safer and more resilient. The current research examines a 6-year-old experimental horizontal levee at the Oro Loma Sanitary District in San Lorenzo, California. Using horizontal transects and quadrat sampling, I compare the success of two planting strategies – a wet meadow and a riparian scrub community – on an ecotone slope. I …

The Role Of School Counselors In Advocating For Social Justice For All Students During The Covid-19 Pandemic, Amna Jaffer

Dissertations

The field of K–12 school counseling has evolved to embrace social–emotional and mental wellness aspects of students in addition to academic and career/college readiness. Social justice advocacy has been added to the role of school counselor by professional and educational entities. What is less clear is how well-versed school counselors are in social justice advocacy competencies, whether they are equipped to lead and advocate for social justice, barriers and accomplishments in doing so, and ways in which this role may be further developed and integrated into the field of school counseling, particularly in the context of the COVID-19 pandemic. As …

Implementation Of The Covid-19 Risk Communication Policy In Pandeglang 2022, Nahda Salimah, Wahyu Sulistiadi

Journal of Indonesian Health Policy and Administration

Currently, the world is experiencing a non-natural disaster, the COVID-19 pandemic. The Indonesian Government issued instructions for handling and controlling COVID-19 by implementing health protocols and vaccinations to reduce the rate of COVID-19 cases. The handling and control of COVID-19 are delivered by increasing public knowledge about COVID-19 through a risk communication approach. Pandeglang area, Banten, had the lowest dose one and two vaccination coverage rates in Banten Province in 2021. Implementing the risk communication policy needs to be considered in successfully handling and controlling COVID-19. This research is qualitative with case study type research. The method of collecting data …

2022-05-29_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus/stats/coronavirus-symptoms. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated twice a week on Mondays and Thursdays.

Syndromic Surveillance System data is obtained from approximately 216 facilities participating in syndromic surveillance (139 Emergency Departments (ED), 77 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, …

Cardiology Implications Of Ed Covid-19 Patients In An Underserved Rural Health Care Environment, Pedro Colio

Dissertations

Background/Purpose: Positive COVID-19 patients with chronic comorbidities have been associated with severe cardiac complications (e.g., STEMI, NSTEMI, myocarditis, pericarditis, AF) specifically among underserved communities. Acute STEMI and NSTEMI are cardiac conditions associated with ruptured atherosclerotic plaque leading to significant myocardial injury. AF, the most common arrhythmia leading to cerebrovascular accidents, is also common in hospitalized patients with severe illnesses. Myocarditis and pericarditis are inflammatory heart conditions associated with acute viral infections. According to the literature, these cardiac issues have been linked as complications of COVID-19. COVID 19 is an emerging, complex, and costly public health challenge globally with potential lifelong …

Increasing Covid-19 Vaccine Awareness Among Hispanic Families: A Policy Perspective, Allison Chico, Iris Vazquez, Claudia Aguayo, Jose Andres Rozo

Doctor of Nursing Practice Final Manuscripts

COVID-19 disproportionally affected Hispanic/Latinx populations exacerbating systemic health inequities. In San Diego County, 44.7% of COVID-19 cases are among Hispanic/Latinxs compared to 31.1% Whites. Community-centered, culturally tailored vaccine programs are essential to close the gap in COVID-19 disparities. This health policy project aimed to explore barriers to COVID-19 vaccination across Hispanics/Latinx in San Diego, communicate findings and seek assistance from elected officials, and collaborate with a community-based organization to provide vaccines utilizing the PRECEDE-PROCEED model. Our project utilized a multicomponent approach. We conducted a screening of 200 participants to identify common barriers for vaccine hesitancy among Hispanics/Latinx individuals across San …

Improving Vaccination Rates Through Community Partnership, Marissa Marquez

Doctor of Nursing Practice Final Manuscripts

IMPROVING VACCINATION RATES THROUGH COMMUNITY PARTNERSHIP

by

Marissa Marquez, DNP Student, FNP-C, MSN, MBA, RN, BSN

Clinical Mentor: Jill Milton, MSN, FNP-C

Joseph Burkard, DNSc, CRNA, AACN Health Policy Fellow

Purpose: The purpose of the quality improvement project is to improve the vaccination rates and vaccine series completion rates of school age children at Rosa Parks Elementary school through a targeted educational intervention.

Background: Under immunization among school-aged children is an ongoing challenge. Low rates of immunization can cause outbreaks of communicable disease, leading to preventable injury, loss of life, and burden to the healthcare system. Among other …

Evaluating The Effectiveness Of Education On The Misuse Of Corticosteroids And Antibiotics For Treatment Of Acute Pharyngitis, Samantha Kaikai

Doctor of Nursing Practice Final Manuscripts

Purpose: This evidence-based practice (EBP) project aims to pilot a nurse practitioner-driven education utilizing the American Family Physician guideline (AFP) “IDSA Updates Guideline for Managing Group A Streptococcal Pharyngitis.” Acute pharyngitis is a frequently observed condition in outpatient clinics, but its optimal management continues to be of concern due to the overuse of antibiotics and corticosteroid treatments. The AFP Guidelines for acute pharyngitis include using the Centor criteria to guide the plan of care and the evidence-based antibiotic therapy for patients who score >4 on the Centor criteria or test positive for the rapid point of care testing.

Background: In …

The Differences In The Susceptibility Patterns To Triclabendazole Sulfoxide In Field Isolates Of Fasciola Hepatica Are Associated With Geographic, Seasonal, And Morphometric Variations, Martha V Fernandez-Baca, Cristian Hoban, Rodrigo A Ore, Pedro Ortiz, Young-Jun Choi, César Murga-Moreno, Makedonka Mitreva, Miguel M Cabada

2020-Current year OA Pubs

Triclabendazole (TCBZ) resistance is an emerging problem in fascioliasis that is not well understood. Studies including small numbers of parasites fail to capture the complexity of susceptibility variations between and within

Beyond Inhibition: A Novel Strategy Of Targeting Hiv-1 Protease To Eliminate Viral Reservoirs, Josh G Kim, Liang Shan

2020-Current year OA Pubs

HIV-1 protease (PR) is a viral enzyme that cleaves the Gag and Gag-Pol polyprotein precursors to convert them into their functional forms, a process which is essential to generate infectious viral particles. Due to its broad substrate specificity, HIV-1 PR can also cleave certain host cell proteins. Several studies have identified host cell substrates of HIV-1 PR and described the potential impact of their cleavage on HIV-1-infected cells. Of particular interest is the interaction between PR and the caspase recruitment domain-containing protein 8 (CARD8) inflammasome. A recent study demonstrated that CARD8 can sense HIV-1 PR activity and induce cell death. …

Hospital Surface Disinfection Using Ultraviolet Germicidal Irradiation Technology: A Review, Robert Scott, Lovleen Tina Joshi, Conor Mcginn

Peninsula Dental School

No abstract provided.

The Time They Are A' Changin': Bilski V. Kappos, Global Tech V. Seb, Stanford V. Roche, And Microsoft V. I4i, Sue Ann Mota

Journal of Technology Law & Policy

Patent law in the United States has been in the process of changing in the last few years due to a series of Supreme Court cases and congressional action. This Article gives an overview of these changes and their implications.

In 2010 and 2011, the U.S. Supreme Court decided four landmark patent cases, each time affirming the Court of Appeals for the Federal Circuit. On June 28, 2010, the Court unanimously held in Bilski v. Kappos that a patent application for claims involving hedging risk in energy markets involved non-patentable subject matter. On May 31, 2011, the Court held 8–1 …

Parasite Hospitality: How Parasitic Helminth Worms Help Researchers Prevent Type 1 Diabetes., Brooke Wynalda

SUURJ: Seattle University Undergraduate Research Journal

The hygiene hypothesis describes how human exposure to parasitic helminth worms (and other microorganisms) impacts immune system functions. The potential impacts include protection against autoimmune and allergic disease. Epidemiological disease mapping reveals cases of allergic and autoimmune disease are disproportionately concentrated in urban, developed countries where there is less risk of parasitic infection. This suggests an inverse correlation between autoimmune diseases and likelihood of helminth infection. These observations have led researchers to posit that helminth worms have coevolved alongside their human host. This hypothesis is supported by helminth antagonization of human anti-inflammatory responses. There is some evidence to suggest that …

The Influence Of Social Capital On Drought-Caused Climate Change: Low-Income Farmer Adaptation., Alex Chapman

SUURJ: Seattle University Undergraduate Research Journal

Climate change continues to destroy ecosystems, cause extreme shifts in weather patterns, and threaten the livelihood of people across the globe. Drought has become one of the most pervasive weather changes, with a particularly hard impact on low-income farmers. In order to combat the impacts of drought, farmers now must take adaptive measures, which include investing in technology, shifting planting schedules, employing different irrigation methods, and more. Social capital has been recognized as an important element in supporting livelihoods, yet it is less clear how social capital influences adaptation to climate change. This paper is a literature review, examining the …

Minutes 2020-2021, Bowling Green State University. Administrative Staff Council

Administrative Staff Council

The records of the Administrative Staff Council (UA-022) are available in print in the Center for Archival Collections.

Cross-Reactive Immunity Against The Sars-Cov-2 Omicron Variant Is Low In Pediatric Patients With Prior Covid-19 Or Mis-C., Juanjie Tang, Tanya Novak, Julian Hecker, Gabrielle Grubbs, Fatema Tuz Zahra, Lorenza Bellusci, Sara Pourhashemi, Janet Chou, Kristin Moffitt, Natasha B. Halasa, Stephanie P. Schwartz, Tracie C. Walker, Keiko M. Tarquinio, Matt S. Zinter, Mary A. Staat, Shira J. Gertz, Natalie Z. Cvijanovich, Jennifer E. Schuster, Laura L. Loftis, Bria M. Coates, Elizabeth H. Mack, Katherine Irby, Julie C. Fitzgerald, Courtney M. Rowan, Michele Kong, Heidi R. Flori, Aline B. Maddux, Steven L. Shein, Hillary Crandall, Janet R. Hume, Charlotte V. Hobbs, Adriana H. Tremoulet, Chisato Shimizu, Jane C. Burns, Sabrina R. Chen, Hye Kyung Moon, Christoph Lange, Adrienne G. Randolph, Surender Khurana

Manuscripts, Articles, Book Chapters and Other Papers

Neutralization capacity of antibodies against Omicron after a prior SARS-CoV-2 infection in children and adolescents is not well studied. Therefore, we evaluated virus-neutralizing capacity against SARS-CoV-2 Alpha, Beta, Gamma, Delta and Omicron variants by age-stratified analyses (5 years of age. As expected, convalescent pediatric COVID-19 and MIS-C cohorts demonstrate higher neutralization titers than hospitalized acute COVID-19 patients. Overall, children and adolescents show some loss of cross-neutralization against all variants, with the most pronounced loss against Omicron. In contrast to SARS-CoV-2 infection, children vaccinated twice demonstrated higher titers against Alpha, Beta, Gamma, Delta and Omicron. These findings can influence transmission, re-infection …

The Trips Agreement: Is It Beneficial To The Developing World, Or Simply A Tool Used To Protect Pharmaceutical Profits For Developed World Manufacturers?, Clark A.D. Wilson

Journal of Technology Law & Policy

There is an ongoing struggle between the rights of pharmaceutical patent owners and those in desperate need of the drugs for whom they hold the patents. Further technological innovation requires that there be sufficient incentive to research and develop (R&D) new drugs, but once these drugs are approved and protected by patent law, they should be made available to people who will suffer without them. In this regard, a system of patent rights which is too protective will hinder availability by restricting widespread dissemination to the public. On the other hand, a system of patent rights which is too weak …

Covid-2019 And Pregnancy: A Narrative Review Of Maternal And Perinatal Outcomes, Nihal Al Riyami, Shahila Sheik

Sultan Qaboos University Medical Journal

As of August 11, 2021, approximately 206 million people worldwide had been infected with SARS-CoV-2. However, limited data are available regarding the effects of COVID-19 infection on pregnancy and maternal and perinatal outcomes. This review aimed to resolve this gap in literature. The MEDLINE®, SCOPUS and Cumulative Index to Nursing and Allied Health Literature databases were searched to identify relevant English-language articles published between January 2020 and February 2021. A total of 17 articles describing the outcomes of 762 pregnancies were identified. There were 613 babies born, including 16 sets of twins. Within the cases studied, 12 (1.6%) maternal deaths …

Early Disseminated Mycobacterium Abscessus Complex Infection In An Infant With Coexisting Cystic Fibrosis And Progressive Familial Intrahepatic Cholestasis: Case Report And Literature Review, Sanjeewani A. Weerakoon, Maya Al Salti, Jalila Mohsin, Hilal Al Hashami, Tawfiq Al Lawati, Hussain Mohsin

Sultan Qaboos University Medical Journal

Mycobacterium abscessus complex (MABSC) is a rapidly growing mycobacterium and may rarely cause disseminated infections in immunocompromised patients. In patients with cystic fibrosis (CF), it peaks between the ages of 11 and 15 years. We present a five-month-old infant with coexisting CF and progressive familial intrahepatic cholestasis (PFIC) who had pulmonary and cutaneous dissemination of MABSC infection. The management of this disseminated infection in an infant with two coexisting chronic diseases was challenging and resulted in the rapid deterioration of lung function and progression of PFIC to liver cirrhosis with a fatal outcome.

Impact Of Hospital Characteristics And Governance Structure On The Adoption Of Tracking Technologies For Clinical And Supply Chain Use: Longitudinal Study Of Us Hospitals, Xiao Zhu, Youyou Tao, Ruilin Zhu, Dezhi Wu, Wai-Kit Ming

Publications

BACKGROUND: Despite the increasing adoption rate of tracking technologies in hospitals in the United States, few empirical studies have examined the factors involved in such adoption within different use contexts (eg, clinical and supply chain use contexts). To date, no study has systematically examined how governance structures impact technology adoption in different use contexts in hospitals. Given that the hospital governance structure fundamentally governs health care workflows and operations, understanding its critical role provides a solid foundation from which to explore factors involved in the adoption of tracking technologies in hospitals. OBJECTIVE: This study aims to compare critical factors associated …

Lessons Learned From The World Health Organization’S Late Initial Response To The 2014-2016 Ebola Outbreak In West Africa, Chulwoo Park

Faculty Research, Scholarly, and Creative Activity

The purpose of this article is to 1) examine the role of the World Health Organization (WHO) in controlling infectious disease outbreaks, 2) evaluate if the WHO’s initial response to the 2014-2016 Ebola crisis was appropriate, 3) evaluate current WHO’s efforts to prevent future disease outbreaks after the Ebola elimination, and 4) suggest how WHO should be further reformed to provide prompt and accurate guidance to multi-sectoral health stakeholders at local, national, regional and global level for effective surveillance preparedness and response. This is a non-systematic narrative literature review. The articles from PubMed, Scopus, Medline, books, WHO documents and websites, …

Amoebic Liver Abscess: A Disease Native To Oman?, Nenad Pandak, Sirous Golchinheydari, Asmaa S. Mahdi, Ali Al Majrafi, Stephen S. Deenadayalan, Faryal Khamis

Sultan Qaboos University Medical Journal

Objectives: Amoebic liver abscess (ALA) is endemic to many areas of the world. This study sought to investigate the epidemiology, presentation, laboratory tests and imaging characteristics of ALA in Oman and ultimately determine whether it is native to Oman or originated abroad. Methods: This case series study was conducted at the Royal Hospital, Muscat, Oman, from January 2013 to December 2017 with patients older than 13 years and having a discharge diagnosis of ALA. Patient data were extracted from the Royal Hospital patient database. Results: 22 patients were included in the study—18 Omani patients and four expatriates. Only two Omanis …

Microbial Sociality In Biofilms, Swetha Kasetty

Dartmouth College Ph.D Dissertations

Biofilms are communities of microorganisms attached to surfaces through various self-secreted matrix materials. Biofilms are dynamic communities with extensive interactions between their residents. Microorganisms compete, cooperate, and communicate with each other in biofilms. These ecological interactions determine the emergence or loss of strains/species and are critical in the formation and proliferation of biofilms. Furthermore, most natural biofilms are formed by multiple microbial species and strains and these interactions within the biofilm dramatically influence community composition and structure over time. Microbial interactions also influence clinically relevant outcomes such as antibiotic resistance and host virulence. In this thesis we explore the potential …