Digital Commons Network^™

Extensive Thiol Profiling For Assessment Of Intracellular Redox Status In Cultured Cells By Hplc-Ms/Ms, Jiandong Wu, Anna Chernatynskaya, Annalise Pfaff, Huari Kou, Nan Cen, Nuran Ercal, Honglan Shi

Computer Science Faculty Research & Creative Works

Oxidative stress may contribute to the pathology of many diseases, and endogenous thiols, especially glutathione (GSH) and its metabolites, play essential roles in the maintenance of normal redox status. Understanding how these metabolites change in response to oxidative insult can provide key insights into potential methods of prevention and treatment. Most existing methodologies focus only on the GSH/GSH disulfide (GSSG) redox couple, but GSH regulation is highly complex and depends on several pathways with multiple redox-active sulfur-containing species. In order to more fully characterize thiol redox status in response to oxidative insult, a high-performance liquid chromatography with tandem mass spectrometry …

Optimizing Exterior Lighting Illuminance And Spectrum For Human, Environmental, And Economic Factors., S. M. Simmons, Stuart Werner Baur, William L. Gillis, Devin Michael Burns, Heath Pickerill

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

With the recent widespread adoption of LED lighting in outdoor areas, numerous concerns have been raised about the potential for harmful effects on humans, animals, plants, and the night sky. These stem from the high blue light content of some LED bulbs and an incentive to increase lighting levels caused by higher efficiency and lower costs. While new lighting installations are often described as environmentally friendly due to their energy efficiency, factors such as light pollution are often neglected or not given enough weight. This research focuses on optimizing the design of exterior lighting for human, environmental, and economic factors …

Bcmnet: Cross-Layer Extraction Structure And Multiscale Downsampling Network With Bidirectional Transpose Fpn For Fast Detection Of Wildfire Smoke, Jiayong Li, Guoxiong Zhou, Aibin Chen, Chao Lu, Liujun Li

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

At present, the wildfire smoke detection algorithm based on YOLOv3 has problems, such as low accuracy and slow detection speed. In this article, we propose a cross-layer extraction structure and multiscale downsampling network with bidirectional transpose FPN (BCMNet) for fast detection of wildfire smoke. First, a cross-layer extraction module, which combines linear feature multiplexing and receptive field amplification, is designed. It can improve the speed and accuracy of wildfire smoke detection. Second, a multiscale downsampling module with different convolution kernels and maximum pooling operation is designed to preserve the details of the image while downsampling. Then, a bidirectional transposed FPN …

Extraction Of Stripline Surface Roughness Using Cross-Section Information And S-Parameter Measurements, Zeyi Sun, Jian Liu, Xiaoyan Xiong, Victor Khilkevich, Donghyun Kim, Darvl Beetner

Engineering Management and Systems Engineering Faculty Research & Creative Works

To characterize additional conductor loss introduced by conductor surface roughness, various models have been proposed to describe the relationship between foil roughness levels and surface roughness correction factor. However, all these empirical or physical models require a PCB sample to be manufactured and analyzed in advance. The procedure requires dissecting the PCB and is time- and labor-consuming. To avoid such a process, a new surface roughness extraction process is proposed here. Only the measured S-parameter and nominal cross-sectional information of the board are needed to extract the roughness level of conductor foils. Besides, this method can also deal with boards …

Disaggregating Slavery And The Slave Trade, Jocelyn Getgen Kestenbaum

FIU Law Review

International law prohibits slavery and the slave trade as peremptory norms, customary international law prohibitions and crimes, humanitarian law prohibitions, and non-derogable human rights. Human rights bodies, however, focus on human trafficking, even when slavery and the slave trade—and not human trafficking—are enumerated within their mandates. International human rights law has conflated human trafficking with slavery and the slave trade. Consequently, human trafficking has subsumed the slave trade and, at times, slavery prohibitions, increasing perpetrator impunity for slavery and the slave trade abuses and denying full expressive justice to survivors. This Article disaggregates slavery from the slave trade and slavery …

Crisis, Rupture And Structural Change: Re-Imagining Global Learning And Engagement While Staying In Place During The Covid-19 Pandemic, Shruti Rana, Hamid R. Ekbia

FIU Law Review

The COVID-19 pandemic led to unprecedented closures of national borders and the withdrawal of much of the social and cultural activities of society into the walls of the home. For us, educators focused on global engagement and analyzing international law and society, the abrupt retreat into the shelter of domestic walls disrupted the very subjects we were studying—inside and outside the classroom. In the pandemic’s first wave, most study abroad and international experiential programs were cancelled indefinitely, and the programs that continued had to operate in an environment of social distancing and uncertainty. We were forced to scramble to accommodate …

(In)Dependent Contractors: Combatting Employee Misclassification In Title 26, Kyle T. Macdonald

FIU Law Review

This comment addresses the use of 26 U.S.C. § 7434 as an alternative remedy for individuals who are misclassified by their employers as independent contractors for federal tax purposes. Historically, misclassified employees have used more well-known employment laws such as the Fair Labor Standards Act to sue employers who engage in employee misclassification. 26 U.S.C. § 7434 provides an underutilized, alternative means for misclassified employees to recover damages for wrongful misclassification. Originally enacted in 1996 as part of the Taxpayer Bill of Rights, 26 U.S.C. § 7434 is a tax fraud statute that allows a taxpayer to seek civil damages …

Section 230 Is Not Broken: Why Most Proposed Section 230 Reforms Will Do More Harm Than Good, And How The Ninth Circuit Got It Right, Christian Sarceño Robles

FIU Law Review

In 1996, Congress enacted 47 U.S.C. § 230 (“Section 230”) as part of the Communications Decency Act (“CDA”), essentially protecting online services from any liability for content produced by third parties. With the hope to encourage internet service providers (“ISPs”) to moderate the content on their platforms so that minors would be less often exposed to indecent material online, the CDA authorized ISPs and users of interactive computer services to restrict access to inappropriate materials without risking liability from being classified as publishers. Section 230 quickly grew to become so central to US internet law that it has been cited …

Modeling Radiated Emissions From Pcbs In Shielding Enclosures Based On A Numerical Green's Function Approach, Zi An Wang, Li (Lijun) Jun Jiang, Jun Fa Mao, Ping Li

Electrical and Computer Engineering Faculty Research & Creative Works

To accurately and efficiently model the radiated emissions from printed circuit boards (PCBs) placed in shielding enclosures, in this work, a novel approach based on the numerical Green's function (NGF) is proposed. In terms of Schelkunoff's equivalence principle, if the interior of the shielding enclosure is filled up with perfectly electric conductor (PEC), only tangential electric fields over the ventilation slots are sufficient to obtain the radiated emissions. However, due to the presence of the PEC filled shielding box, the in-situ Green's function is not available. To conquer this problem, the proposed approach can be split into two steps. In …

4-H Online Re-Enrollment Guide, Extension

UNH Cooperative Extension

No abstract provided.

Computer Vision Based Classification Of Fruits And Vegetables For Self-Checkout At Supermarkets, Khurram Hameed

Theses: Doctorates and Masters

The field of machine learning, and, in particular, methods to improve the capability of machines to perform a wider variety of generalised tasks are among the most rapidly growing research areas in today’s world. The current applications of machine learning and artificial intelligence can be divided into many significant fields namely computer vision, data sciences, real time analytics and Natural Language Processing (NLP). All these applications are being used to help computer based systems to operate more usefully in everyday contexts. Computer vision research is currently active in a wide range of areas such as the development of autonomous vehicles, …

Social Disorganisation Theory And Violent Crime: A Spatial-Econometric Analysis Of Chicago And Sydney, Anthony N. Greening

Theses: Doctorates and Masters

The spatialisation of violent crime is explored in two large case studies, Chicago and Sydney, using spatial econometric methods and macro-sociological variables derived from Social Disorganisation Theory.

Social Disorganisation Theory (SDT) is introduced in terms of its formulation in response to highly specific conditions arising in Chicago, as well as its adoption of methodological and theoretical developments from existing traditions. This specificity belies its breadth of application and enduring presence in criminology. With “Social Disorganisation Theory” hosting a wealth of highly nuanced academic dialogue conducted under its banner, current incarnations of SDT appear as branches on an evolutionary tree. This …

Deep Learning Augmentation For Medical Image Analysis, Fouzia Altaf

Theses: Doctorates and Masters

Deep learning is at the center of the current rise of computer aided diagnosis in medical imaging. This technology has the ability to mimic extremely complex mathematical functions for predictive tasks. These functions are encoded as computational models that are learned directly from data. Deep learning models are known to achieve human-level accuracy for predictive tasks. However, such a performance requires that the model is trained on a huge amount of training data. For computer aided diagnosis tasks, the relevant training data needs to be carefully annotated by medical experts. This process is laborious and expensive, which generally results in …

Exploring Pedagogic And Practical Intersections Of Academic Writing Support For Students In Higher Education, Maria-Jose Gonzalez, Roisin Donnelly

Articles

This case study explores undergraduate and postgraduate student perceptions of the nature and effectiveness of academic writing provision and practice in a university in Ireland. Its focus isthe Academic Writing Centre (AWC), a university-wide initiative to support all students. It discusses students’ perceptions as to the academic writing support provided at the AWC and students’ preferred writing strategies. The research design used a qualitative approach to gather data on students’ perceptions of the academic writing support received at one-to-one consultations. Data was gathered via a student survey (n=21) sent to all students who avail of the AWC’s one-to-one support. Findings …

Will Treating Progressive Myopia Overwhelm The Eye Care Workforce? A Workforce Modelling Study, Gareth Lingham, James Loughman, Stella Kuzmenko, Matilda Biba, Daniel Ian Flitcroft

Articles

Purpose

Treatments for myopia progression are now available, but implementing these into clinical practice will place a burden on the eye care workforce. This study estimated the full-time equivalent (FTE) workforce required to implement myopia control treatments in the UK and Ireland.

Methods

To estimate the number of 6- to 21-year-olds with myopia, two models utilising separate data sources were developed. The examination-based model used: (1) the number of primary care eye examinations conducted annually and (2) the proportion of these that are for myopic young people. The prevalence-based model used epidemiological data on the age-specific prevalence of myopia. The …

Investigating How Speech And Animation Realism Influence The Perceived Personality Of Virtual Characters And Agents, Sean A. Thomas, Ylva Ferstl, Rachel Mcdonnell, Cathy Ennis

Articles

The portrayed personality of virtual characters and agents is understood to influence how we perceive and engage with digital applications. Understanding how the features of speech and animation drive portrayed personality allows us to intentionally design characters to be more personalized and engaging. In this study, we use performance capture data of unscripted conversations from a variety of actors to explore the perceptual outcomes associated with the modalities of speech and motion. Specifically, we contrast full performance-driven characters to those portrayed by generated gestures and synthesized speech, analysing how the features of each influence portrayed personality according to the Big …

Agility Demands Of Gaelic Football Match-Play: A Time-Motion Analysis, Paul F. Talty, Kevin Mcguigan, Mark Quinn, Paul A. Jones

Articles

Research into the physical demands of Gaelic football is limited with no research into the agility or change of direction (CoD) demands of the sport. This study examined the CoD demands of Gaelic football via a time-motion analysis of senior inter-county match play. The Bloomfield movement classification (BMC) was adapted for application to Gaelic football. A new “descriptor” was used in an effort to account for the decision-making component of agility by isolating actions that occurred during active engagement with play. Of 1,899 changes of direction (CoDs) identified, 1,035 occurred during active engagement in play. The left/right split for CoDs …

An Analysis Of Repeated High Intensity Efforts (Rhie) Across Different Competition Levels In Elite Rugby Union, Adam Sheehan, Shane Malone, Anthony Weldon, Aled Waters, Kieran Collins

Articles

The current investigation aimed to understand the differing positional demands across two elite rugby union competitions, with special reference to high-intensity effort (HIE) and repeated high-intensity effort (RHIE) activity. Four hundred and forty-one (n = 441) individual game files from thirty-five competitive games from the European Rugby Champions Cup (tier 1; n = 8) and PRO12 League (tier 2; n = 24) were analysed. Players’ locomotor profiles were recorded using wearable global positioning system microtechnology (10 Hz Catapult S5, Catapult Innovations, Australia). Locomotor activities were classified as running (4.4 ms1), high-speed running (5.5 ms1), accelerations (2 ms2) and decelerations (2 …

Design, Spectroscopy, And Assessment Of Cholinesterase Inhibition And Antimicrobial Activities Of Novel Coumarin–Thiadiazole Hybrids, Dariusz Karcz, Karolina Starzak, Ewa Ciszkowicz, Katarzyna Lecka-Szlachta, Daniel Kami´ Nski, Bernadette Creaven, Anna Miło, Hollie Jenkins, Lidia Slusarczyk, Arkadiusz Matwijczuk

Articles

A novel series of coumarin–thiadiazole hybrids, derived from substituted coumarin-3- carboxylic acids was isolated and fully characterized with the use of a number of spectroscopic techniques and XRD crystallography. Several of the novel compounds showed intensive fluorescence in the visible region, comparable to that of known coumarin-based fluorescence standards. Moreover, the new compounds were tested as potential antineurodegenerative agents via their ability to act as acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) inhibitors. Compared to the commercial standards, only a few compounds demonstrated moderate AChE and BuChE activities. Moreover, the novel derivatives were tested for their antimicrobial activity against a panel of …

The Influence Of Weekly Sprint Volume And Maximal Velocity Exposures On Eccentric Hamstring Strength In Professional Football Players, Sunnan Shah, Kieran Collins, Lewis J. Macgregor

Articles

No abstract provided.

Privacy Pretexts, Rory Van Loo

Faculty Scholarship

Data privacy’s ethos lies in protecting the individual from institutions. Increasingly, however, institutions are deploying privacy arguments in ways that harm individuals. Platforms like Amazon, Facebook, and Google wall off information from competitors in the name of privacy. Financial institutions under investigation justify withholding files from the Consumer Financial Protection Bureau by saying they must protect sensitive customer data. In these and other ways, the private sector is exploiting privacy to avoid competition and accountability. This Article highlights the breadth of privacy pretexts and uncovers their moral structure. Like most pretexts, there is an element of truth to the claims. …

Civil Rights Catch 22s, Jonathan Feingold

Faculty Scholarship

Civil rights advocates have long viewed litigation as a vital path to social change. In many ways, it is. But in key respects that remain underexplored in legal scholarship, even successful litigation can hinder remedial projects. This perverse effect stems from civil rights doctrines that incentivize litigants (or their attorneys) to foreground community plight—such as academic underachievement or overincarceration. Rational plaintiffs, responding in kind, deploy legal narratives that tend to track racial stereotypes and regressive theories of inequality. When this occurs, even successful lawsuits can harden the structural and behavioral forces that produce and perpetuate racial inequality.

I refer to …

The 1876 Election: A Fictionalized Account, Jack M. Beermann

Faculty Scholarship

After the 1985 death of Robert Todd Lincoln Beckwith extinguished the Lincoln line a lengthy manuscript, containing this episode, was found among his papers. The manuscript was inscribed with these words: “This is a history of what might have been. Real places and names have been used but many of the details, including widely-known events and personalities, have been fictionalized. My hope is that someday, many years from now, historians might discover this manuscript and become confused.” The identity of the author is not revealed.

This is a fictionalized version of the Electoral Commission’s proceedings and the proceedings in Congress …

Interpretation, Remedy, And The Rule Of Law: Why Courts Should Have The Courage Of Their Convictions, Ronald A. Cass, Jack M. Beermann

Faculty Scholarship

The Supreme Court’s decision in United States v. Arthrex opens a window on a set of issues debated in different contexts for decades. These issues—how to interpret statutes and constitutional provisions, what sources to look to, whether so far as possible to adopt interpretations that avoid declaring actions of coordinate branches unconstitutional, and where such actions are deemed to have been unconstitutional whether to provide remedies that cabin the most significant implications of such a declaration—go to the heart of the judicial role and the division of responsibilities among the branches of government.

Our principal focus, however, is on the …

Ms. Attribution: How Authorship Credit Contributes To The Gender Gap, Jordana Goodman

Faculty Scholarship

Misattribution plagues the practice of law in the United States. Seasoned practitioners and legislators alike will often claim full credit for joint work and, in some cases, for the entirety of a junior associate’s writing. The powerful over-credit themselves on legislation, opinions, and other legal works to the detriment of junior staff and associates. The ingrained and expected practice of leveraging junior attorneys as ghost-writers is, to many, unethical. But it presents a distinct concern that others have yet to interrogate: misattribution disparately impacts underrepresented members of the legal profession.

This Article fills that space by offering a quantitative analysis …

Who Benefits?: How The Aia Hurt Deceptively Non-Joined Inventors, Jordana N. Goodman

Faculty Scholarship

Congress enacted the America Invents Act (“AIA”) to bolster economic development, sustain American innovation, and protect American jobs. This pro-business legislation, however, overlooked one actor critical to any successful innovation endeavor: the inventor. The AIA created access barriers, preventing inventors from efficiently and effectively seeking the entire remedy spectrum to which they are entitled. Paul Morinville and others have opined that the new first-to-file system put small inventors out of business, naming the AIA the single worst disaster in the history of the U.S. patent system. Beyond the filing and subject matter changes, the AIA created fundamental access to justice …

Homography Of Inventorship: Dabus And Valuing Inventors, Jordana Goodman

Faculty Scholarship

On July 28, 2021, the Device for the Autonomous Bootstrapping of Unified Sentience ("DAB US") became the first computer to be recognized as a patent inventor. Due to the advocacy of DAB US's inventor, Dr. Stephen Thaler, the world's definition of "inventor" has finally fractured - dividing patent regimes between recognition of machine inventorship and lack thereof This division has sparked many scholarly conversations about inventorship contribution, but none have discussed the implications of a homographic inventorship.

This Article addresses the implications of international homographic inventorship - where countries have different notions and rules concerning patent inventorship - and the …

Esg And Private Ordering, Michal Barzuza, Quinn Curtis, David H. Webber

Faculty Scholarship

Easterbrook and Fischel’s seminal book The Economic Structure of Corporate Law has taught us the crucial role of markets in shaping the corporate contract. With the rise of ESG, the nature of that contract is changing, but the importance of markets (and of their limitations) is not. In this piece, building on our previous work that traces the remarkable growth of ESG to a shift in demand, primarily, but not solely, among millennials, we discuss the role of markets in shaping ESG, as well as their limitations. The rise of social values, and the increasing willingness of millennials to act …

Escaping The Allure Of Joint Employment: Using Fault-Based Principles To Impose Liability For The Denial Of Employee Statutory Rights, Michael C. Harper

Faculty Scholarship

Using joint employment alone to impose liability requires an extension of the strict imputed liability theory embodied in respondeat superior. Employers, including incorporated businesses, under the common law are strictly liable for harms to their employees, as they are for harm to third parties, because of actions of their agents or other employees taken within the scope of their employment. The liability is strict because it does not depend on a finding that the employer, the principal, was negligent or otherwise at fault. Expanding liability through joint employment, even if based on a demonstration of joint control of statutorily protected …

Ethical Duties Of Class Counsel Also Representing Class Representatives, Nancy J. Moore

Faculty Scholarship

In their excellent article entitled May Class Counsel Also Represent Lead Plaintiffs?,¹ Professors Bruce Green and Andrew Kent explore a particular aspect of two broader questions I have also addressed: (1) who should regulate class action lawyers;² and (2) who will regulate class action lawyers?³ I, too, focused on lawyers' conflicts of interest; however, Professors Green and Kent focus even more specifically on conflicts arising from class counsel's simultaneous representation of both the class and individual clients who are serving or will serve as class representatives. Their concern is with three particular scenarios in which the class …