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2022

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Bayesian Network Development And Validation For Siting Selection, Abdullah Hassan Battawi Aug 2022

Bayesian Network Development And Validation For Siting Selection, Abdullah Hassan Battawi

Theses and Dissertations

In this study, increasing electricity demand requires considerable attention to increasing the diversity of power generation. Alternative energy can produce heating and power systems and thermal storage. Our objective and every organization’s objectives are to minimize its energy consumption cost under electricity demand uncertainty. In rural areas, heat and power availability and stability are also crucial. Combined heat and power have proven their effectiveness as a subsequent to Electricity. This paper identified four criteria and eleven sub-criteria to determine the most appropriate structure location for combined heat and power in the rural community. The Bayesian Network technology has been applied …


Effects Of The In Ovo Administration Of The Poulvac E. Coli Vaccine In Layer Hatching Eggs On Hatchability, Hatchling Characteristics, And Early Posthatch Chick Performance, Lauren L. Lindsey Aug 2022

Effects Of The In Ovo Administration Of The Poulvac E. Coli Vaccine In Layer Hatching Eggs On Hatchability, Hatchling Characteristics, And Early Posthatch Chick Performance, Lauren L. Lindsey

Theses and Dissertations

Avian Pathogenic E. coli can lead to infections in laying hens and wide-spread economic problems in the table egg industry. A vaccine widely used to combat APEC is the Poulvac E. coli vaccine, which is normally applied via spray vaccination. Application of this vaccine via in ovo injection has not been examined. The purpose of this series of studies was to determine the effects of injecting 50 μL of different dosages of the PECV into Hy-Line W-36 layer hatching eggs on the hatchability and characteristics of the hatchlings, and on the livability and characteristics of the chicks through 21 d …


Effectiveness Of Food-Grade Coating Treated Nets After Various Drying Methods At Controlling Mite Growth On Dry-Cured Hams, Sadie White Aug 2022

Effectiveness Of Food-Grade Coating Treated Nets After Various Drying Methods At Controlling Mite Growth On Dry-Cured Hams, Sadie White

Theses and Dissertations

Tyrophagus putrescentiae, known as the ham mite, is the most difficult pest to control in the dry-cured ham industry. Food-grade propylene glycol coated nets have been studied as an alternative to conventional mite infestation treatments but were heavy and costly to ship. This study aimed to increase the ease of use of the coated nets via drying. Three drying treatments: oven dried for 7 min (OD7m), oven dried for 20 min (OD20m), and counter dried for 24 h (CD24h), were tested to determine the efficacy at controlling mites as well as the mechanical properties of the nets and sensory characteristics …


Backyard Grower-Consumer Perceptions Of Rabbit Meat Consumption In Rural Mississippi, Mildred Elizabeth Murphree Aug 2022

Backyard Grower-Consumer Perceptions Of Rabbit Meat Consumption In Rural Mississippi, Mildred Elizabeth Murphree

Theses and Dissertations

Every country in the world is affected by one or more forms of malnutrition. Malnutrition includes three conditions: undernutrition, micronutrient deficiencies or excesses, or overnutrition. Obesity is a greater contributor to death than undernutrition. Age, sex, ethnicity, socioeconomic status, and education level affect obesity. The rates of obesity vary considerably between states and regions of the country. The state of Mississippi is ranked as the poorest state in the nation and Mississippi has the highest adult obesity rate at 40.8% (Farberman & Kelley, 2020).

Rabbit meat production and consumption is a possible solution to malnutrition worldwide (Petrescu & Petrescu-Mag, 2018). …


Effects Of Mass Death On Community Structure And Ecosystem Function, Abby Kimpton Jones Aug 2022

Effects Of Mass Death On Community Structure And Ecosystem Function, Abby Kimpton Jones

Theses and Dissertations

Death and decomposition are natural processes that are generally well-understood. However, large events of death, such as mass mortality events (MMEs) are increasing in frequency and their impacts on the ecosystem are largely unknown. These events may have both bottom-up effects from increased nutrient input as well as top-down effects from loss of an ecological functional group by the affected population. Different functional MMEs may result in different top-down effects, creating cascading effects. In Chapter 1, I test the hypothesis that scavenger and herbivore simulated MMEs generate novel bottom-up and top-down effects. Results indicate that MMEs have a significant effect …


Soybean Potassium Utilization During Reproductive Growth Stages In Response To Potassium Timing, Potassium Rate, Herbicide Injury, And Desiccation, Tyler Lawrence Richmond Aug 2022

Soybean Potassium Utilization During Reproductive Growth Stages In Response To Potassium Timing, Potassium Rate, Herbicide Injury, And Desiccation, Tyler Lawrence Richmond

Theses and Dissertations

Potassium (K) deficiency of soybean [Glycine max (Merr.) L.] is common throughout the Mid-Southern region of the United States. Visual symptoms of K deficiency may be absent or subtle during early and mid-reproductive growth stages. Correcting K deficiency in-season is problematic due to limited research. Information regarding soybean yield response to in-season fertilizer K application time is limited to growth stages prior to the onset of R1. Research is also limited on new higher yielding soybean cultivars. The objective of this study was to evaluate influences of in-season K application timing during reproductive growth stages on soybean yield. Field experiments …


The Level Of Burnout And Job Satisfaction Among Mississippi Agriculture Educators And The Potential Level Of Impact From The Covid-19 Pandemic, Anna Hollis Aug 2022

The Level Of Burnout And Job Satisfaction Among Mississippi Agriculture Educators And The Potential Level Of Impact From The Covid-19 Pandemic, Anna Hollis

Theses and Dissertations

Many states across the country have felt the impact of a nationwide teacher shortage. Specifically, the state of Mississippi has experienced a shortage of certified agricultural education teachers. Unfortunately, during a time, a novel virus (Coronavirus or COVID-19) swept the entire world and shook the academic world to its core. Like the majority, educators were encouraged to adopt a variety of approaches to better flow with the changes in their “normal” routines. Many researchers have suggested that teachers are leaving education due to little resources, recognition, and high job demands, which correlates to poor job satisfaction and symptoms of burnout. …


Assessing Virtual Free-Choice Agricultural Learning: A Mixed Methods Approach, Richard John Kennedy Aug 2022

Assessing Virtual Free-Choice Agricultural Learning: A Mixed Methods Approach, Richard John Kennedy

Theses and Dissertations

Since the mid-19th century, agricultural museums and living history sites, first in Scandinavia and then in the United States and Canada, have provided historical, cultural, and, sometimes, scientific information about farming to visitors. Many of these visitors have been school children on field trips. Assessment of this learning, however, has been scant, particularly within the free-choice style inherent in these types of educational venues. At the same time, assessment of free-choice learning, often analyzed through the Contextual Model of Learning (Falk & Dierking 2000), has taken place at educational sites like zoos, natural history museums, and science centers. This study, …


Effects Of Anthropogenic Global Change On A Grassland Prairie Community, Carter Wolff Aug 2022

Effects Of Anthropogenic Global Change On A Grassland Prairie Community, Carter Wolff

Theses and Dissertations

Anthropogenic global change is altering food web dynamics. Global change comprises factors, like temperature, sound, light and more. In this dissertation, I evaluate how two factors, sound and temperature, alter prairie communities. In Chapter 1, I test if sound influences grasshopper respiration rate, thereby altering diet. Some sound frequencies increased grasshopper respiration rate while others decreased respiration rate. Frequencies that elevated respiration rate led to grasshoppers consuming more carbohydrate-rich foods compared to protein-rich foods. This diet change stems from a carbon deficit due to increased respiration rate and could act as a mechanism by which sound pollution indirectly alters plant …


Inosine 5’- Monophosphate Derived Umami Flavor Intensity Of Beef Determination By Electrochemistry And Chromatography, Kezia Virellia To Aug 2022

Inosine 5’- Monophosphate Derived Umami Flavor Intensity Of Beef Determination By Electrochemistry And Chromatography, Kezia Virellia To

Theses and Dissertations

The umami sensation contributes to beef flavor and acceptability. Inosine 5’- monophosphate (IMP) was the most abundant nucleotide in meat known to impart umami taste which thus far had been overlooked in meat flavor studies. The objectives of this study were to determine the umami taste threshold of inosine 5'-monophosphate (IMP), the effects of spiking IMP on the sensory descriptive attributes of various USDA graded beef strip steaks, and to differentiate beef by IMP content using electrochemistry. USDA Prime, Choice, and Select steaks were spiked with 0.3 and 0.6 mM IMP and analyzed chemically and organoleptically. Liquid chromatography-mass spectrometry and …


How And With Whom You Spend Your Time Matters: An Examination Of Familial Relationships, Leisure Activities, And Dementia Development, Erika Cooksey Mcdaniel Aug 2022

How And With Whom You Spend Your Time Matters: An Examination Of Familial Relationships, Leisure Activities, And Dementia Development, Erika Cooksey Mcdaniel

Theses and Dissertations

Dementia is an interminable disorder characterized by a decrease in cognitive functioning behavioral and emotional changes, and an overall diminishment in quality of life that usually affects the older population. In the coming decades, scientists estimate that the number of sufferers will reach over 100 million worldwide. Though there is currently no cure for any form of dementia, the theory of cognitive reserve posits certain lifestyle characteristics (i.e., educational attainment, SES, and/or career path) can mitigate the risk of dementia by improving cognitive resilience over an individual’s lifetime. The current study sought to discover what, if any, effects familial relationships, …


Maternal Nutrient Restriction And Melatonin Supplementation Alter Neurotransmitter Pathways In Bovine Fetal And Placental Tissues, Allison R. Harman Aug 2022

Maternal Nutrient Restriction And Melatonin Supplementation Alter Neurotransmitter Pathways In Bovine Fetal And Placental Tissues, Allison R. Harman

Theses and Dissertations

Nutrient restriction is a relatively common production insult to pregnancy in cattle. Recently, melatonin supplementation has been investigated as a possible therapeutic to rescue the negative effects of nutrient restriction. Neurotransmitters have been implicated as having negative programming effects in mouse and human pregnancies, manifested as metabolic and neurologic disorders. The role of neurotransmitters in fetal development has only begun to be understood in mice and humans. Neurotransmitters have not been analyzed in cattle, much less within the context of a compromised pregnancy. Brangus heifers were allotted to one of four treatments (ADQ-CON, RES-CON, ADQ-MEL, RES-MEL) in either Fall 2019 …


The Effect Of Learner Profiling On Fourth Grade English Students' Pirls Achievement Scores Of Students Whose Teachers Are Credentialed Or Non-Credentialed, Raynor Stuart Roberts Aug 2022

The Effect Of Learner Profiling On Fourth Grade English Students' Pirls Achievement Scores Of Students Whose Teachers Are Credentialed Or Non-Credentialed, Raynor Stuart Roberts

Doctoral Dissertations and Projects

As the world enters the knowledge-based economy, schools across the globe look to teach up so students can become lifelong learners. Educators focus on implementing instructional best practices that will promote increased student achievement. The current study aims to determine if a significant interaction exists between teacher credentialing and the pedagogical act of learner profiling that would affect student Progress in International Reading Literacy Study (PIRLS) achievement scores. PIRLS is a recognized reading assessment proctored to over sixty-one countries that measures and benchmarks fourth-grade students’ reading achievement. The researcher deployed a quantitative, quasi-experimental nonequivalent control-group study to observe four groups …


Cognitive Abilities Of Criminal Justice Leaders, Dustin Joe Addison Aug 2022

Cognitive Abilities Of Criminal Justice Leaders, Dustin Joe Addison

Doctoral Dissertations and Projects

The purpose of this applied study was to help in the understanding of how stress has a significant impact on criminal justice leadership. The research design with the applied study was multimethod. The multimethod design correlated interviews, surveys, and archival data to understand the correlation between stress events and perceived cognitive abilities. The central questions within this study were related to prolonged exposure to high stress and whether criminal justice leaders have a lower cognitive ability than those not exposed to high-stress situations. With the malleability of the human brain allowed by neuroplasticity, do criminal justice leaders have altered abilities …


Clinical Significance Of Evaluation Of Some Metabolic And Hematological Parameters In Patients With Sudden Sensorineural Hearing Loss, Eman S. Abd El-Gaffar, Gehan M. S. Abd El-Salam, Hala M. Abd El-Samad Aug 2022

Clinical Significance Of Evaluation Of Some Metabolic And Hematological Parameters In Patients With Sudden Sensorineural Hearing Loss, Eman S. Abd El-Gaffar, Gehan M. S. Abd El-Salam, Hala M. Abd El-Samad

Journal of Medicine in Scientific Research

Background Sudden sens orineural hearing loss (SSNHL) is a medical emergency, being mostly an idiopathic disease. Understanding the pathogenesis of SSNHL may help physicians for diagnosis and intervention. Objective The aim of the present study was to investigate some metabolic and hematological parameters in patients with SSNHL and related them to their clinical condition. Patients and methods The study was conducted on 50 patients with SSNHL and 20 age-matched and sex-matched controls. Both groups were subjected to audiological and laboratory evaluation of their fasting blood sugar (FBS), lipid profile, thyroid function test, neutrophil–lymphocyte ratio, and platelet–lymphocyte ratio. Moreover, the relation …


Grk2 Regulates Adp Signaling In Platelets Via P2y1 And P2y12., Xuefei Zhao, Matthew Cooper, James V Michael, Yanki Yarman, Aiden Baltz, J Kurt Chuprun, Walter J Koch, Steven E. Mckenzie, Maurizio Tomaiuolo, Timothy J Stalker, Li Zhu, Peisong Ma Aug 2022

Grk2 Regulates Adp Signaling In Platelets Via P2y1 And P2y12., Xuefei Zhao, Matthew Cooper, James V Michael, Yanki Yarman, Aiden Baltz, J Kurt Chuprun, Walter J Koch, Steven E. Mckenzie, Maurizio Tomaiuolo, Timothy J Stalker, Li Zhu, Peisong Ma

Department of Medicine Faculty Papers

The critical role of G protein-coupled receptor kinase 2 (GRK2) in regulating cardiac function has been well documented for >3 decades. Targeting GRK2 has therefore been extensively studied as a novel approach to treating cardiovascular disease. However, little is known about its role in hemostasis and thrombosis. We provide here the first evidence that GRK2 limits platelet activation and regulates the hemostatic response to injury. Deletion of GRK2 in mouse platelets causes increased platelet accumulation after laser-induced injury in the cremaster muscle arterioles, shortens tail bleeding time, and enhances thrombosis in adenosine 5'-diphosphate (ADP)-induced pulmonary thromboembolism and in FeCl3-induced carotid …


Cross-Linked Chitosan/Gelatin Beads Loaded With Chlorella Vulgaris Microalgae/Zinc Oxide Nanoparticles For Absorbing Carcinogenic Bisphenol-A Pollutant From Water, Hazim M Ali, Omar M Ibrahim, Ahmed S M Ali, Mahmoud A Mohamed, Rehab Y Ghareeb, Elsayed E Hafez, Mohamed R El-Aassar Aug 2022

Cross-Linked Chitosan/Gelatin Beads Loaded With Chlorella Vulgaris Microalgae/Zinc Oxide Nanoparticles For Absorbing Carcinogenic Bisphenol-A Pollutant From Water, Hazim M Ali, Omar M Ibrahim, Ahmed S M Ali, Mahmoud A Mohamed, Rehab Y Ghareeb, Elsayed E Hafez, Mohamed R El-Aassar

2020-Current year OA Pubs

Water polluted by phenolic compounds is a global threat to health and the environment; accordingly, we prepared a green novel sorbent biological system from a chitosan (CS), gelatin (GT), and


Technology-Delivered Adaptations Of Motivational Interviewing For The Prevention And Management Of Chronic Diseases: Scoping Review, Havisha Pedamallu, Matthew J Ehrhardt, Julia Maki, April Idalski Carcone, Melissa M Hudson, Erika A Waters Aug 2022

Technology-Delivered Adaptations Of Motivational Interviewing For The Prevention And Management Of Chronic Diseases: Scoping Review, Havisha Pedamallu, Matthew J Ehrhardt, Julia Maki, April Idalski Carcone, Melissa M Hudson, Erika A Waters

2020-Current year OA Pubs

BACKGROUND: Motivational interviewing (MI) can increase health-promoting behaviors and decrease health-damaging behaviors. However, MI is often resource intensive, precluding its use with people with limited financial or time resources. Mobile health-based versions of MI interventions or technology-delivered adaptations of MI (TAMIs) might increase reach.

OBJECTIVE: We aimed to understand the characteristics of existing TAMIs. We were particularly interested in the inclusion of people from marginalized sociodemographic groups, whether the TAMI addressed sociocontextual factors, and how behavioral and health outcomes were reported.

METHODS: We employed the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines for scoping reviews to conduct …


Defective Homologous Recombination In Aged Mice, Vindhya Kilaru, Lakshmi Paniker, Maria Sandoval, Suhani Bhakta, Francesca Cole Aug 2022

Defective Homologous Recombination In Aged Mice, Vindhya Kilaru, Lakshmi Paniker, Maria Sandoval, Suhani Bhakta, Francesca Cole

Summer Experience 2022

No abstract provided.


Elucidating The Role Of Microbiome In Low- And High-Grade Glioma, Aditi Manjrekar, Golnaz Morad, Matthew Wong, Ashish Damania, Pranoti Sahasrabhojane, Sarah Johnson, Sherise D. Ferguson, Nadim J. Ajami, Jennifer A. Wargo Aug 2022

Elucidating The Role Of Microbiome In Low- And High-Grade Glioma, Aditi Manjrekar, Golnaz Morad, Matthew Wong, Ashish Damania, Pranoti Sahasrabhojane, Sarah Johnson, Sherise D. Ferguson, Nadim J. Ajami, Jennifer A. Wargo

Summer Experience 2022

No abstract provided.


Tumor Cell Specific Function Of Il-1 Signaling In The Pathogenesis Of K-Ras Mutant Lung Cancer, Milind Mutala, Avantika Krishna, Bo Yuan, Michael J. Clowers, Seyed Javad Moghaddam Aug 2022

Tumor Cell Specific Function Of Il-1 Signaling In The Pathogenesis Of K-Ras Mutant Lung Cancer, Milind Mutala, Avantika Krishna, Bo Yuan, Michael J. Clowers, Seyed Javad Moghaddam

Summer Experience 2022

Department of Pulmonary Medicine


Lipocalin 2 Protects From Lung Tumorigenesis Associated With Gut Microbiota Alterations, Elizabeth L. Tang, Humam Kadara, Zahraa Rahal Aug 2022

Lipocalin 2 Protects From Lung Tumorigenesis Associated With Gut Microbiota Alterations, Elizabeth L. Tang, Humam Kadara, Zahraa Rahal

Summer Experience 2022

No abstract provided.


Characterization Of Glioblastoma Stem Cells, Joelly Cortes, Diangelo Gonzalez, Sam Mcleod, Aadhya Tiwari, Sadhan Majumder Aug 2022

Characterization Of Glioblastoma Stem Cells, Joelly Cortes, Diangelo Gonzalez, Sam Mcleod, Aadhya Tiwari, Sadhan Majumder

Summer Experience 2022

No abstract provided.


Effects Of Parp Inhibitors, Sglt2 Inhibitors, And Colchicine On Doxorubicin-Induced Premature Senescence Induced-Phenotype, Michelle Xiaoyi Lu, Jun-Ichi Abe, Sivareddy Kotla, Kyung Ae Ko, Samanthapudi K. Venkatasubrahman Aug 2022

Effects Of Parp Inhibitors, Sglt2 Inhibitors, And Colchicine On Doxorubicin-Induced Premature Senescence Induced-Phenotype, Michelle Xiaoyi Lu, Jun-Ichi Abe, Sivareddy Kotla, Kyung Ae Ko, Samanthapudi K. Venkatasubrahman

Summer Experience 2022

No abstract provided.


Regulator Of G Protein Signaling 14 Disruption Affects The Gut Microbiota And Metabolome In Mice, C R. Longoria, O Ibironke Phd, L J. Kerkhof Phd, M Oydanich, X Su Phd, E Chiles, S F. Vatner Md, S C. Campbell Phd Facsm Aug 2022

Regulator Of G Protein Signaling 14 Disruption Affects The Gut Microbiota And Metabolome In Mice, C R. Longoria, O Ibironke Phd, L J. Kerkhof Phd, M Oydanich, X Su Phd, E Chiles, S F. Vatner Md, S C. Campbell Phd Facsm

International Journal of Exercise Science: Conference Proceedings

See Attached Abstract


Transcending The Impasse: Towards An Indigenous Vision Of Legality In Palestine, Juman Abujbara Aug 2022

Transcending The Impasse: Towards An Indigenous Vision Of Legality In Palestine, Juman Abujbara

LLM Theses

This thesis attempts to demonstrate that the international legal impasse surrounding Palestine is animated by incommensurable visions of legality. It argues that in portraying the Palestinian struggle for liberation as a struggle for state sovereignty, international law subjects the indigenous worldview to a violent and perpetual erasure. The thesis employs Aaron Mills' theoretical framework to argue for an incommensurability between Palestine's indigenous conception of legality and the dominant conception of legality underlying international law. Further, the thesis offers a reading of Ghassan Kanafani's novel The Other Thing to explore the consequences and normative implications of an impasse characterized by incommensurability. …


Protecting Our Pets: Nebraska’S Domestic Abuse Protection Orders And Pets, Josiah J. Shanks Aug 2022

Protecting Our Pets: Nebraska’S Domestic Abuse Protection Orders And Pets, Josiah J. Shanks

Nebraska Law Bulletin (Selected Issues)

It is now well-understood that there is a link between violence toward animals and community-involved violence. And abusers typically escalate their abuse as it goes on. Unfortunately, abuse victims frequently stay within the confines of their relationship out of fear, especially when pets are involved. Protection orders are effective at protecting abuse victims, and their pets, from abusers.

Pets play a unique role in our lives and the law. Pets need to be expressly accounted for within protection order statutes. Half-measures, such as relying on a catch-all provision or updating protection order forms, are not enough. Currently, Nebraska’s protection order …


Accepting The Unacceptable: Trinity Western University, Religious Freedom, And The Meaning Of Liberal Constitutionalism, Robert Stephen Boissonneault Aug 2022

Accepting The Unacceptable: Trinity Western University, Religious Freedom, And The Meaning Of Liberal Constitutionalism, Robert Stephen Boissonneault

LLM Theses

This thesis proposes an answer to the question of when, and under what conditions, a state operating within the framework of liberal constitutionalism may legitimately condition receipt of public benefits on the recipient's conformity with liberal values—a question that is implicitly asked, but never directly answered, by the decision of the Supreme Court of Canada in Law Society of British Columbia v Trinity Western University. How this question is answered has significant implications for the law of religious freedom in Canada. This thesis posits a conceptual distinction between two types of public benefit: public licences and public mandates. This distinction …


Time Domains Of Hypoxia Responses And -Omics Insights, James J. Yu, Amy L. Non, Erica C. Heinrich, Wanjun Gu, Joe Alcock, Esteban A. Moya, Elijah S. Lawrence, Michael S. Tift, Katie A. O'Brien, Jay F. Storz, Anthony V. Signore, Jane I. Khudyakov, William K. Milsom, Sean M. Wilson, Cynthia M. Beall, Francisco C. Villafuerte, Tsering Stobdan, Colleen G. Julian, Lorna G. Moore, Mark M. Fuster, Jennifer A. Stokes, Richard Milner, John B. West, Jiao Zhang, John Y. Shyy, Ainash Childebayeva, José Pablo Vázquez-Medina, Luu V. Pham, Omar A. Mesarwi, James E. Hall, Zachary A. Cheviron, Jeremy Sieker, Arlin B. Blood, Jason X. Yuan, Tatum S. Simonson, Et Al. Aug 2022

Time Domains Of Hypoxia Responses And -Omics Insights, James J. Yu, Amy L. Non, Erica C. Heinrich, Wanjun Gu, Joe Alcock, Esteban A. Moya, Elijah S. Lawrence, Michael S. Tift, Katie A. O'Brien, Jay F. Storz, Anthony V. Signore, Jane I. Khudyakov, William K. Milsom, Sean M. Wilson, Cynthia M. Beall, Francisco C. Villafuerte, Tsering Stobdan, Colleen G. Julian, Lorna G. Moore, Mark M. Fuster, Jennifer A. Stokes, Richard Milner, John B. West, Jiao Zhang, John Y. Shyy, Ainash Childebayeva, José Pablo Vázquez-Medina, Luu V. Pham, Omar A. Mesarwi, James E. Hall, Zachary A. Cheviron, Jeremy Sieker, Arlin B. Blood, Jason X. Yuan, Tatum S. Simonson, Et Al.

School of Biological Sciences: Faculty Publications

The ability to respond rapidly to changes in oxygen tension is critical for many forms of life. Challenges to oxygen homeostasis, specifically in the contexts of evolutionary biology and biomedicine, provide important insights into mechanisms of hypoxia adaptation and tolerance. Here we synthesize findings across varying time domains of hypoxia in terms of oxygen delivery, ranging from early animal to modern human evolution and examine the potential impacts of environmental and clinical challenges through emerging multi-omics approaches. We discuss how diverse animal species have adapted to hypoxic environments, how humans vary in their responses to hypoxia (i.e., in the context …


Circadian Rhythms Mediate Infection Risk In Daphnia Dentifera, Alaina C. Pfenning-Butterworth, David T. Nguyen, Jessica L. Hite, Clayton E. Cressler Aug 2022

Circadian Rhythms Mediate Infection Risk In Daphnia Dentifera, Alaina C. Pfenning-Butterworth, David T. Nguyen, Jessica L. Hite, Clayton E. Cressler

School of Biological Sciences: Faculty Publications

Biological rhythms mediate important within-host processes such as metabolism, immunity, and behavior which are often linked to combating disease exposure. For many hosts, exposure to pathogens occurs while feeding. However, the link between feeding rhythms and infection risk is unclear because feeding behavior is tightly coupled with immune and metabolic processes which may decrease susceptibility to infection. Here, we use the Daphnia dentifera–Metschnikowia bicuspidata host–pathogen system to determine how rhythms in feeding rate and immune function mediate infection risk. The host is known to have a nocturnal circadian rhythm in feeding rate, yet we found that they do not exhibit …