Digital Commons Network^™

Post–Lung Transplantation Outcomes And Ex Vivo Histopathological Findings In Severe Post-Covid-19 Pulmonary Disease—A Single-Center Experience, Hana Javaid, Masayuki Nigo, Bihong Zhao, Daniel Ocazionez Trujillo, Rodrigo Hasbun, Luis Ostrosky-Zeichner, Manish Patel, Soma Jyothula

Faculty, Staff and Student Publications

BACKGROUND: A significant proportion of patients with severe and persistent coronavirus disease 2019 (COVID-19) require continuous ventilatory support and occasional extracorporeal membrane oxygenation (ECMO) for acute respiratory distress syndrome (ARDS). Lung transplantation is a treatment option for patients who develop severe ARDS.

METHODS: Our lung transplant database was retrospectively reviewed for patients who underwent lung transplantation for COVID-19 pulmonary disease at Memorial Hermann Hospital, Texas Medical Center, Houston, Texas, from January 2020 to March 2022. We evaluated outcomes of patients who were followed in our clinic at least 6 months post-transplant. Pretransplant patient characteristics, COVID-19-related treatment, histopathology results, and postdischarge …

Digital Money & Central Bank Digital Currency (Cbdc) - New Opportunity, New Challenge, G.A. Walker

The International Lawyer

No abstract provided.

Visualizing Politics In Indonesia: The Design And Distribution Of Election Posters, Colm A. Fox

Research Collection School of Social Sciences

Where studies have shown that visuals are the primary means of political communication, research continues to focus largely on text-based information. To add to our understanding of visual-political communications, this article analyses Indonesian election posters since the 1950s. Drawing on historical materials and on a content analysis of 4,000 election posters, it asks why election posters have been designed and distributed in particular ways. Findings indicate that in the past, posters used singular, though powerful, social symbols to mobilize demographic groups behind political parties. However, contemporary posters are more visually complex and more candidate-centered, making arguments as to what the …

Apoptotic Brown Adipocytes Enhance Energy Expenditure Via Extracellular Inosine, Birte Niemann, Saskia Haufs-Brusberg, Laura Puetz, Martin Feickert, Michelle Y Jaeckstein, Anne Hoffmann, Jelena Zurkovic, Markus Heine, Eva-Maria Trautmann, Christa E Müller, Anke Tönjes, Christian Schlein, Azin Jafari, Holger K Eltzschig, Thorsten Gnad, Matthias Blüher, Natalie Krahmer, Peter Kovacs, Joerg Heeren, Alexander Pfeifer

Faculty, Staff and Student Publications

Brown adipose tissue (BAT) dissipates energy

"Cerulean Skies" By Maria Schneider: A Formal And Semiotic Analysis, Jonathan Heim

Dissertations, Theses, and Capstone Projects

Expressivity, imagery, and narrativity have long been touted as hallmarks of big band composer Maria Schneider’s style. This perception is widely accepted by critics and casual commentators, but are these attributions merely metaphorical or do they speak to observable dimensions of Schneider’s compositional style? This dissertation aims to address the narrative and expressive dimensions of Schneider’s music by combining aspects of formal analysis with concepts from music semiotics. The centerpiece is an analysis of “Cerulean Skies” (2006), the longest work to date in Schneider’s oeuvre with a duration of approximately twenty-two minutes. “Cerulean Skies” is distinct in its expansiveness and …

Interpreting Jean Coulthard's Concerto For Piano And Orchestra (1963): A Pianist's Perspective, Jocelyn Lai

Dissertations, Theses, and Capstone Projects

Jean Coulthard (1908-2000) is recognized as one of Canada’s most prolific and important female classical composers in the twentieth century. She remained creatively active from her hometown of Vancouver, British Columbia, for eight decades, resulting in a catalog of over 350 works representing most classical music genres. Her music continues to be performed and recorded by renowned ensembles and soloists such as the Vancouver Symphony Orchestra, CBC Vancouver Orchestra, Calgary Philharmonic, Purcell String Quartet, pianists John Ogdon and Jane Coop, and contralto Maureen Forrester. Coulthard is known for her distinctive coloristic sonorities reminiscent of those in works by European composers …

"Secession's Moving Foundation": Fugitive Slave Rendition And The Politics Of American Slavery, Evan Turiano

Dissertations, Theses, and Capstone Projects

This dissertation examines the political conflict over fugitive slave rendition from the era of the American Revolution through the passage of the 1850 Fugitive Slave Law. It pays particular attention to the struggle over the legal rights due to African Americans accused of being fugitive slaves. Slaveholders claimed an absolute property right over accused fugitive slaves and argued that any recognition of legal remedies for accused runaways threatened that right. Free African Americans and their allies in the abolitionist movement asserted that Black people accused of having escaped slavery were due a legal process. This was a vital protection against …

Bearing Il/Liberal Secondary Witness: Un/Disciplined Pedagogies Of Response To Testimonial Narratives, Queenie T. Sukhadia

Dissertations, Theses, and Capstone Projects

This dissertation is preoccupied with secondary witnessing—the process of readerly subjects receiving and responding to testimonial accounts of state-sponsored torture and genocide that they themselves have not experienced firsthand. It examines how certain secondary witnessing postures and practices have been made commonsense for readers—public readerly subjectivities as well as professionalized ones such as literary critics—by liberal discourses, technologies, and institutions, while others have been rendered imperceptible by being represented as too delayed, too quixotic, or too unfeasible. My dissertation understands ‘liberalism’ as a tripartite entity: first, the onto-epistemologies inaugurated and normalized by the Enlightenment, that also authorized the violent processes …

The Politics Of Feminist Citizenship: Violence, Law, And Affect In Post-Revolution Tunisia, Ola Galal

Dissertations, Theses, and Capstone Projects

Taking a historical and ethnographic approach, this dissertation examines citizenship as a historical, political, and ethical problem in Tunisia during a turbulent yet hopeful time of transition. It examines changes in the conceptualization of citizenship from one that is construed as a favor to one that is rights-based, and the political, ethical, and material effects of that shift in both official and popular discourses. I home in on the central and sometimes uneasy role feminists play in articulating and consolidating that discursive, legal, and affective transformation in citizenship by mediating between different legal and moral frameworks and attempting to reconcile …

Refusing Rehabilitation: Outlaw Epistemologies And The Carceral-Therapeutic State In Nyc, Nadja Eisenberg-Guyot

Dissertations, Theses, and Capstone Projects

During an historic re-articulation of incarceration in New York City, Refusing Rehabilitation: Outlaw Epistemologies and the Carceral-Therapeutic State explores how gender, race, and class have been transformed at the intersection of criminal legal system reform and the overdose crisis. I take up how multiracial groups of criminalized women—thrown together by the state, not by choice—refuse forms of state control and violence, and imagine together alternative “outlaw” horizons of justice, healing, drug use, and escape from carceral-therapeutic capture. Countering the individualizing mandate of rehabilitation, women in rehab articulate visions of healing grounded in interdependence, collective safety, and an end to structural …

Prenatal Choline Supplementation During Maternal Obesity Alters Offspring Response To Western Diets, Hunter W. Korsmo

Dissertations, Theses, and Capstone Projects

Maternal obesity has led to an increase in adverse offspring developmental outcomes and a greater risk for long-term metabolic diseases. Choline, a semi-essential nutrient, can be incorporated into phosphatidylcholine (PC) as well as sphingomyelin (SM) and donate its labile methyl group for the remethylation of homocysteine after choline is oxidized to betaine. Prenatal choline insufficiency has been related to maternal obesity and metabolic diseases, such as metabolic associated fatty liver disease (MAFLD). Choline may interact with maternal obesity to influence the programming offspring.

Chapter 1 presents an introduction of choline and the various clinical outcomes associated with choline supplementation during …

Influence Level Prediction On Social Media Through Multi-Task And Sociolinguistic User Characteristics Modeling, Denys Katerenchuk

Dissertations, Theses, and Capstone Projects

Prediction of a user’s influence level on social networks has attracted a lot of attention as human interactions move online. Influential users have the ability to influence others’ behavior to achieve their own agenda. As a result, predicting users’ level of influence online can help to understand social networks, forecast trends, prevent misinformation, etc. The research on user influence in social networks has attracted much attention across multiple disciplines, from social sciences to mathematics, yet it is still not well understood. One of the difficulties is that the definition of influence is specific to a particular problem or a domain, …

Isolation And Characterization Of Fluorescent Proteins And Small Molecules From Marine Vertebrates, Sara Rose Krivoshik

Dissertations, Theses, and Capstone Projects

Fluorescence is a phenomenon in which a wavelength of light excites a fluorophore and then emits light at a higher, longer wavelength. This occurs throughout the biological world, in both the terrestrial and marine realms. Encompassing a diverse set of mechanisms from small molecules to large protein complexes; fluorescence has been used as a biological tool with a wide range of applications to study molecular and cellular biology for decades. This dissertation looks to identify and characterize novel fluorescent proteins and small molecules to allow for more efficient translation in developing new biotechnologies. Using a combination of RNA-Seq, Mass-Spec, protein …

The Effects Of False Heartbeat Feedback On Moral Judgment, Scott Koenig

Dissertations, Theses, and Capstone Projects

Research on human morality is at a crossroads, with one side claiming that moral judgment is the result of rational inference and the other side claiming that it is the result of emotion-laden intuition. This study investigated whether emotion drives moral judgment by manipulating a core component of the experience of emotion: physiological arousal. The sample consisted of 77 undergraduate students at Brooklyn College (57% women, 43% men; mean age = 20.1). One group of participants was led to believe their heart was beating quickly, and another group slowly, while they read and evaluated a series of text vignettes depicting …

Expulsive Greening: A Cross-Sectional Analysis Of Green Gentrification In The Resilience Paradigm, Brooklyn 2010–2020, Rose Jimenez

Dissertations, Theses, and Capstone Projects

Background: This project analyzes the spatial coincidence between gentrification typologies and urban greening in Brooklyn, New York from 2010 to 2020. Assets formed under the NYC Green Infrastructure Program were chosen as a proxy for urban greening to represent the spatial practice specifically within the 21st-century climate change resilience paradigm of development. Methods: First, five indexes measuring variations of economic and demographic conditions related to gentrification were applied to Brooklyn for comparative analysis: NOAA’s Social Vulnerability Indicators of Gentrification Pressure, The NYC Heat Vulnerability Index, The Small Area Index of Gentrification, Typologies of Gentrification and Displacement, and The Housing Risk …

Recovering Authenticity: Care, Conversation And Value, Shannon M. Brick

Dissertations, Theses, and Capstone Projects

Suppose you learn that your steak-loving friend has just adopted a vegan diet. You ask her what prompted the change, and she tells you that someone she trusts recently tweeted “Eating meat is immoral.” Your friend’s response is a little disappointing and shallow, but why? Most of our knowledge comes from trusting what other people tell us, so why, when it comes to moral matters, does deference seem inappropriate? Some philosophers think it’s because moral testimony cannot transmit important epistemic goods, like knowledge or understanding. Others think that when people defer to moral testimony, their actions or characters will be …

The Storytelling Cure: Medicine And Narrative From Galen To Shahrazad And Rousseau, Ryan A. Milov-Cordoba

Dissertations, Theses, and Capstone Projects

Are stories healing? This dissertation introduces and explores an idea that I call “the storytelling cure.” With this term I capture a set of related notions about the healing power of stories that span literary studies, intellectual history, philosophy, and medical practice. Through a comparative study I make the case for “the storytelling cure” as a cross-cultural, multiconfessional, and multilingual phenomenon of great age, complexity, and power, worthy of the most sustained attention by the contemporary field of Comparative Literature. Concretely, this dissertation presents three extended case studies of “storytelling cures” from three different kinds of texts (case history, frame …

Novel Therapeutic Strategies For Alzheimer’S Disease: Prostaglandin D2 Signaling And Its Human Polymorphisms As Well As A Polypharmacological Approach, Charles H. Wallace

Dissertations, Theses, and Capstone Projects

Alzheimer’s disease (AD) is an age related neurodegenerative disease with pathology that includes amyloid plaques, neurofibrillary tangles and non-resolving neuroinflammation. Non-resolving neuroinflammation lasts the entire course of the disease and has deleterious effects and is often thought to accelerate AD pathology. Non-Steroidal Anti-inflammatory Drugs (NSAIDs) have commonly been used as therapeutics to treat pain, inflammation and vascular. NSAIDs work by altering the cyclooxygenase (COX) mediated biosynthesis of prostaglandins which are lipid mediators that have many physiological functions, for example nociception, inflammation and vasodilation. Epidemiological studies support the notion that NSAIDs could be used to treat AD. Yet, clinical trials using …

A Study Of Entrainment In Speech As A Possible Predictor Of Perceived Trust, Mariana Graterol Fuenmayor

Dissertations, Theses, and Capstone Projects

This thesis explores the possibility of using features of speech as possible predictors of perceived trust. It specifically focuses on entrainment, the tendency of participants in a conversation to unconsciously adapt their manner of talking to become more or less similar to each other. We compile a corpus of interviews conducted in English, with different levels of formality and discussing different topics. With it, we distribute a set of surveys to assess raters’ judgment of the participants, focusing on whether they believe the interviewee is trusted by their conversational partner, and whether they find the interlocutors themselves trustworthy. We also …

Banarasipan As Revelation: Immanent Utopias In The Performance Of Everyday Life, Bhargav Rani

Dissertations, Theses, and Capstone Projects

This dissertation locates itself at the intersection of performance theory, South Asian studies and philosophy of history to examine the history of an urban consciousness known as banarasipan (literally, "Banarasi-ness") as performed by the people of Banaras in northern India. Over the course of the twentieth century, banarasipan, as a distinct way of being in everyday life, has been characterized by its valorization of heroic laziness, seditious laughter, subversive obscenities, and by its egalitarian subjectivity that overrides sectarian and class differences. In the context of South Asian history, this dissertation interrogates the theoretical premises of both Marxist and postcolonial modes …

The Microscopical Evidence Traces Analysis Of Household Dust And Its Statistical Significance As A Definitive Identification Technique, Stephanie Polifroni

Dissertations, Theses, and Capstone Projects

Evidence found at crime scenes is used to assist in creating a link the suspect, the victim, and the scene. As stated by the Locard’s Principle, every contact leaves a trace, that evidence can be used to link together an investigation. Traces are collected in hopes that they can be identified and associated to an individual or individuals to help solve that particular crime. However, the strongest conclusion for evidence traces is an association to a source, and unless a physical match of some kind is found, an individualization cannot be established even when known sample is available. However, having …

Competitive And Facilitative Interactions Between Pavlovian Cues In Human Associative Learning: A Behavioral And Neural Analysis, Fahd Alhazmi

Dissertations, Theses, and Capstone Projects

Learning to anticipate significant events accurately is a crucial element of survival for all species. The process by which animals acquire this knowledge has been a central question of psychological research. A fundamental assumption of many learning theories is that the predictive value assigned to cues is not simply determined by their probability of reinforcement but rather by their ability to compete with other cues present during learning. The assumption of cue competition has significantly contributed to the development of behavioral and neuroscience research for decades, as it has opened the door to new empirical and theoretical advances on the …

Women And Ventriloquism In Early Modern English Drama, Ja Young Jeon

Dissertations, Theses, and Capstone Projects

Bringing together feminist and theater-centered readings, this dissertation examines the status of female vessels that foreign voices inhabit and animate in early modern drama, arguing that the Greek model of ventriloquism represented by the Pythia exerted a powerful influence on the period’s ideas about women’s speech. In feminist work on ventriloquism, despite highlighting theatrical performance’s dependence on citationality, ventriloquism has been largely understood as an analogue for exploring male poets’ authorial power to appropriate women’s voices. In these readings, the term ‘ventriloquist’ is mainly identified with the person who throws his voice into human or nonhuman objects, reminding us of …

Development And Characterization Of A Novel, Genetically- Encoded Sensor To Image Sonic Hedgehog Signaling In Functional Circuits, Sonia Bernal

Dissertations, Theses, and Capstone Projects

Dynamic neurotransmitter and neuromodulator signaling in functional circuits is the neural substrate of animal behavior and cognition. The study of said circuits requires tools with sufficient spatiotemporal dynamics that can probe complex signaling patterns and decode their functional relevance by coupling the signal to behavioral output, ideally in awake, behaving animals. Much is known about the role of classical neurotransmitters such as dopamine in behavior, but a wide variety of peptides and small molecules also regulate neuronal transmission. One of these is Shh, whose presence has been observed in a variety of brain regions known to modulate movement, perception, and …

The Interaction Of Different Primary Producers And Physical And Chemical Dynamics Of An Urban Shallow Lake, Majid Sahin

Dissertations, Theses, and Capstone Projects

An artificial urban shallow lake, Prospect Park Lake (PPL), is situated on a terminal moraine in Brooklyn New York, and supplied with municipal water treated with ortho-phosphates. The constant input of the phosphate nutrient is the primary source of eutrophication in the lake. The numerous pools along the water course houses various aquatic phototrophs, which influence the water quality and the state of the system, driving conditions into favoring the survival of their species. In the first half of the dissertation, the focus of the project is on analyzing how the different primary producers in different regions of PPL affect …

Drag, Drugs, And Demonstrations: Cultural Subversion Under Capitalism, Nicholas Kade Edwards

Dissertations, Theses, and Capstone Projects

In this essay, I will define cultural institutionalization and articulate the ways in which the phenomenon modulates subversive countercultural movements and integrates them into Western, capitalist cultural structures. I will then illustrate my theory of cultural institutionalization by analyzing three historical case studies of subversive countercultural movements in the United States. The first of which will be the drag queen phenomenon, which provides the most convincing case for the theory in the artistic sphere. Secondly, I will address a more explicitly political movement, the black liberation movement and its various permutations: the civil rights movement, the black power movement and …

Oxytocin, A Lover And A Fighter: Maternal Trauma Exposure And Mother-Child Coregulation, Patricia M. Pehme

Dissertations, Theses, and Capstone Projects

The placenta is responsible for regulating the fetal growth and environment in preparation for the anticipated external life. To succeed, it continuously adapts and weaves in a variety of neuroendocrine signals from the maternal organism. If a mother was exposed to trauma and her physiology sustained a change in the functioning of the immune, autonomic and/or endocrine systems, the placenta may anticipate different external environments for her children as compared to children of mothers without trauma exposure. This dissertation examined possible underlying mechanisms of psychosocial trauma transmission from one generation to the next via the placental oxytocinergic pathway. Encompassing three …

A Repository Of Books By Women From The Arab World Translated To English, Nadia El Mouldi

Dissertations, Theses, and Capstone Projects

The translation of women writers from the Arab world in the West contributes to the harmful and inaccurate stereotyping of women from the region in the Global North as oppressed and silenced. In this paper, I describe the rationale and building process for “The repository of books by women from the Arab world translated to English”, a digital project built to counter this flattened image of women from the Arab world by shedding light on the books translated so far and exposing the patterns in the choice and translation of books from Arabic to English. I start by discussing the …

Gamma Protocadherin Synaptic Localization And Intracellular Trafficking Is Consistent With Distinct Adhesive And Anti-Adhesive Roles In Development, Nicole Lamassa

Dissertations, Theses, and Capstone Projects

Clustered protocadherins (Pcdhs) constitute a family of cell adhesion molecules with approximately 60 Pcdh genes clustered in a 1 MB locus on chromosome 5q31 in humans. The Pcdh gene cluster is subdivided into α, β, and γ subclusters which encode related proteins. Individual neurons activate different subsets of Pcdh-α, Pcdh-β and Pcdh-γ genes by epigenetic mechanisms to generate distinct Pcdh adhesive units expressed by each neuron. This is thought to serve as a “surface barcode” for single-cell identity and synaptic recognition in the nervous system. The actual role for Pcdhs in neural development is still relatively unknown and different roles …

Generation Of Mycobacterium Smegmatis Model Systems For Testing Inhibitors Of The Mycobactin Siderophore Of Mycobacterium Tuberculosis, Gabrielle A. Germain

Dissertations, Theses, and Capstone Projects

Mycobacterium tuberculosis (Mtb) is the pathogenic bacterium causative of tuberculosis. According to the 2021 World Health Organization (WHO) Global Tuberculosis (TB) Report, there were approximately 5.8 million TB cases in 2020, and 1.3 million TB deaths among HIV negative people in that year. The rise of multi-drug resistant Mtb strains has increased the need for more potent microbials against this pathogen. Biosynthesis of iron scavenging molecules, known as siderophores (e.g., mycobactin and carboxymycobactin), has been identified as a potential drug target candidate since iron acquisition has been directly linked to the survival and virulence of Mtb. Salicyl-AMS (Sal-AMS) is …