Digital Commons Network^™

Early Life Exposure To Unpredictable Parental Sensory Signals Shapes Cognitive Development Across Three Species, Elyssia Poggi Davis, Kari Mccormack, Hina Arora, Desiree Sharpe, Annabel K. Short, Jocelyne Bachevalier, Laura M. Glynn, Curt A. Sandman, Hal S. Stern, Mar Sanchez, Tallie Z. Baram

Psychology Faculty Articles and Research

Exposure to early life adversity has long term consequences on cognitive function. Most research has focused on understanding components of early life adversities that contribute to later risk, including poverty, trauma, maltreatment, and neglect. Whereas these factors, in the aggregate, explain a significant proportion of emotional and cognitive problems, there are serious gaps in our ability to identify potential mechanisms by which early life adversities might promote vulnerability or resilience. Here we discuss early life exposure to unpredictable signals from the caretaker as an understudied type of adversity that is amenable to prevention and intervention. We employ a translational approach …

Accelerate Construction Of New Pattern Of Ecological Protection In Northwest China, Qi Feng, Guangzu Bai, Zongxing Li, Bao Wang, Lijuan Chen, Penglong Wang, Tengfei Yu, Hongfei Meng, Wen Liu, Zhixiang Lu, Tingting Ning, Chengqi Zhang, Meng Zhu

Bulletin of Chinese Academy of Sciences (Chinese Version)

Based on a profound understanding of the great significance of constructing an ecological protection pattern in Northwest China, this paper systematically summarizes the achievements, new problems and new trends of ecological protection in Northwest China, and accordingly, puts forward an overall spatial arrangement for the ecological protection under "two regions (watersheds)-six zones (core ecological function zones)-multiple points (key ecological points)". In addition, a key path to construct a new pattern of ecological protection in Northwest China is expounded in order to make more contributions to the acceleration of the harmonious co-existence between human and nature. The path is mainly based …

The Image Of God: A Reflection Of Order And Suitability In Design, Mary D. Mckenzie

Doctoral Dissertations and Projects

In the history of biblical interpretation and dogmatic speculation, the “image of God” in humanity has proved remarkably prolific as a source of exegetical and theological discussion. In Genesis 1:26–27, the Bible expounds that God created man in His own image, and in His image, he created male and female. The literature on this topic continues to be overwhelming despite several exhaustive treatments spanning decades among biblical scholars. The act of posing several questions resulted in different answers from various sources. For example, what exactly is the image of God? Is the image of God spiritual or physical? Is the …

Trends In Nutrients Load And Driving Factors In Illinois River Basins, Olaoluwa David Oladuji

Theses and Dissertations

The demand for clean and potable water increases as the population number grows, and surface water serves as a significant source of water supply to many municipalities. However, the quality of surface waters is altered due to excess load of nutrients in the water bodies. For example, excess nitrate and dissolved phosphorus in water may lead to eutrophication. The 2019 bi-annual Illinois Nutrient Loss Reduction Strategies reported about 13% and 35% increases in nitrate and total phosphorus, respectively, across the statewide basins compared to the previous baseline data of 1980-1996. The biannual report stated that Illinois River basin was a …

Vista: October 20, 2022, University Of San Diego

USD Vista (1965-)

No abstract provided.

Kenyon Collegian - October 20, 2022

The Kenyon Collegian

No abstract provided.

Monodelphis Domestica Induced Pluripotent Stem Cells Reveal Metatherian Pluripotency Architecture, Satish Kumar, Erica De Leon, Jose C. Granados, Deanne J. Whitworth, Jane F. Vandeberg

School of Medicine Publications

Marsupials have been a powerful comparative model to understand mammalian biology. However, because of the unique characteristics of their embryology, marsupial pluripotency architecture remains to be fully understood, and nobody has succeeded in developing embryonic stem cells (ESCs) from any marsupial species. We have developed an integration-free iPSC reprogramming method and established validated iPSCs from two inbred strains of a marsupial, Monodelphis domestica. The monoiPSCs showed a significant (6181 DE-genes) and highly uniform (r2 [95% CI] = 0.973 ± 0.007) resetting of the cellular transcriptome and were similar to eutherian ESCs and iPSCs in their overall transcriptomic profiles. …

Human Journeys In The Digital Age: Advances And Challenges In Digital Historical Migration Studies, Paul Longley Arthur, Isabel Smith

Research outputs 2022 to 2026

Accelerations in migration, mobility, and processes of globalization in recent decades have intersected with parallel developments in information and communications technology (ICT). These advances have had profound influences on historical and cultural research. With reference to a diverse range of international projects, this paper outlines major directions and opportunities in the growing field of Digital Historical Migration Studies (DHMS). The “digital turn” brings opportunities for integrating data on macro and micro scales, and finding new ways to combine and explore tensions between quantitative and qualitative materials, and between external observations of migrants and migration and self-representations by migrants. The plural …

Enriched Dietary Saturated Fatty Acids Induce Trained Immunity Via Ceramide Production That Enhances Severity Of Endotoxemia And Clearance Of Infection, Amy L. Seufert, James W. Hickman, Ste K. Traxler, Rachael M. Peterson, Trent A. Waugh, Sydney L. Lashley, Natalia Shulzhenko, Ruth J. Napier, Brooke A. Napier

Biology Faculty Publications and Presentations

Trained immunity is an innate immune memory response that is induced by a primary inflammatory stimulus that sensitizes monocytes and macrophages to a secondary pathogenic challenge, reprogramming the host response to infection and inflammatory disease. Dietary fatty acids can act as inflammatory stimuli, but it is unknown if they can act as the primary stimuli to induce trained immunity. Here we find mice fed a diet enriched exclusively in saturated fatty acids (ketogenic diet; KD) confer a hyper-inflammatory response to systemic lipopolysaccharide (LPS) and increased mortality, independent of diet-induced microbiome and hyperglycemia. We find KD alters the composition of the …

A Phenomenological Study Design Of Receiving Student Feedback: Professor Shared Experiences, James Sigler

Doctoral Dissertations and Projects

The purpose of this transcendental phenomenological study was to describe the experience of using student feedback for professors at higher-education accredited institutions in the United States of America. The essential question of this research was what are the lived experiences of professors when receiving feedback from students? This research found that professors use student feedback if the feedback is found to be valid. The essence of the phenomena was found using the guiding theory of feedback intervention created by Kluger and DeNisi. The 10 professors of this study represented a combined teaching tenure of over 200 years of experience who …

Control Of Ribosomal Rna Synthesis By Hematopoietic Transcription Factors, Charles Antony, Subin S George, Justin Blum, Patrick Somers, Chelsea L Thorsheim, Dexter J Wu-Corts, Yuxi Ai, Long Gao, Kaosheng Lv, Michel G Tremblay, Tom Moss, Kai Tan, Jeremy E Wilusz, Austen R D Ganley, Maxim Pimkin, Vikram R Paralkar

Faculty, Staff and Students Publications

Ribosomal RNAs (rRNAs) are the most abundant cellular RNAs, and their synthesis from rDNA repeats by RNA polymerase I accounts for the bulk of all transcription. Despite substantial variation in rRNA transcription rates across cell types, little is known about cell-type-specific factors that bind rDNA and regulate rRNA transcription to meet tissue-specific needs. Using hematopoiesis as a model system, we mapped about 2,200 ChIP-seq datasets for 250 transcription factors (TFs) and chromatin proteins to human and mouse rDNA and identified robust binding of multiple TF families to canonical TF motifs on rDNA. Using a 47S-FISH-Flow assay developed for nascent rRNA …

Integrated Host-Microbe Plasma Metagenomics For Sepsis Diagnosis In A Prospective Cohort Of Critically Ill Adults, Katrina L Kalantar, Pratik Sinha, Et Al.

2020-Current year OA Pubs

We carried out integrated host and pathogen metagenomic RNA and DNA next generation sequencing (mNGS) of whole blood (n = 221) and plasma (n = 138) from critically ill patients following hospital admission. We assigned patients into sepsis groups on the basis of clinical and microbiological criteria. From whole-blood gene expression data, we distinguished patients with sepsis from patients with non-infectious systemic inflammatory conditions using a trained bagged support vector machine (bSVM) classifier (area under the receiver operating characteristic curve (AUC) = 0.81 in the training set; AUC = 0.82 in a held-out validation set). Plasma RNA also yielded a …

The Wages Of Crying Life: What States Must Do To Protect Children After The Fall Of Roe, Leah A. Plunkett, Michael S. Lewis

Pepperdine Law Review

In the post-Roe world, can a state rationally claim that the value of human life justifies the imposition of abortion bans but does not demand that a state protect the vulnerable young who are “born human beings”—commonly called “minors” or “children”—and are entitled to protection under a state’s laws? This essay advances the claim that it cannot. This essay asks that those who say they are “Pro-life” in politics and law demonstrate that they protect vulnerable life beyond the abortion context, and that they do so in the most minimal fashion: through a demonstrated commitment to protecting the basic welfare …

Tolkien As A Literary Artist: Exploring Rhetoric, Language And Style In The Lord Of The Rings By Thomas Kullmann And Dirk Siepmann, Sharon L. Bolding

Mythlore: A Journal of J.R.R. Tolkien, C.S. Lewis, Charles Williams, and Mythopoeic Literature

No abstract provided.

Well, I’M Back: Samwise Gamgee And The Future Of Tolkien’S Literary Pastoral, Mg Prezioso

Mythlore: A Journal of J.R.R. Tolkien, C.S. Lewis, Charles Williams, and Mythopoeic Literature

This article examines the treatment of the literary pastoral in The Lord of the Rings in order to demonstrate that Tolkien’s pastoral, often considered a vestige of authorial nostalgia, is as forward-looking as it is wistful. Through Samwise Gamgee and his connection to the Shire, Tolkien presents a pastoral that, though rooted in memory, is as mutable as nature itself – one that orients the reader forward and conveys that change is not only something to be accepted, but also embraced.

“What Happened To Battles Are Ugly Affairs?”: Fighting Girls In The Films The Chronicles Of Narnia, Chapters 1, 2 And 3, Anne-Frédérique Mochel-Caballero

Mythlore: A Journal of J.R.R. Tolkien, C.S. Lewis, Charles Williams, and Mythopoeic Literature

Although C.S. Lewis’s Chronicles of Narnia (1950-1956) are still hugely popular today, some critics have accused the books of representing masculinity and femininity in an outmoded way. The three Walden Media films, The Lion, the Witch and the Wardrobe (2005), Prince Caspian (2008) and The Voyage of the Dawn Treader (2010), appear to adopt a more contemporary perspective, especially as far as the representation of fighting girls is concerned. While Lewis seemed slightly reluctant to show women playing an active role on the battlefield, Andrew Adamson, who directed the first two films, lets Susan, the female protagonist, fight alongside the …

Echoing Ecopoetics: Fantasy Literature's Background Sounds, Catherine Olver

Mythlore: A Journal of J.R.R. Tolkien, C.S. Lewis, Charles Williams, and Mythopoeic Literature

Despite David Abram’s fear that reading disrupts people’s “attunement to environing nature,” fantasy literature can vibrantly convey how to hear our environments as it describes characters attuning their ears to particular places. Garth Nix’s Old Kingdom series (1995-2021) and Patrick Ness’s Chaos Walking trilogy (2008-10) develop an echoing ecopoetics of place through both world-building and style. Their fantasy worlds emphasize that characters must relearn to listen in unfamiliar environments: adjusting their expectations and interpretations of background sounds, recognising significant silences, adapting to new ways of communicating, and seeking meaning in nonhuman sounds rather than dismissing them as noise. Their stylistic …

History In The Margins: Epigraphs And Negative Space In Robin Hobb’S Assassin’S Apprentice, Matthew Oliver

Mythlore: A Journal of J.R.R. Tolkien, C.S. Lewis, Charles Williams, and Mythopoeic Literature

Robin Hobb’s Assassin’s Apprentice demonstrates a significant effect of epic fantasy’s conventions for creating the history of a fictional world. By prefacing each chapter with an epigraph from an official in-world historical text before giving a first-person personal narrative, the novel blurs the boundaries between text and paratext, public and private, official history and personal myth-making. This structure raises questions about what is central and marginal in history, suggesting the extent to which historical narrative is constructed in the imagination by taking the facts surrounding a central event from which the historian is absent—a process much like negative space drawing …

David Lindsay's The Violet Apple, Eric Wills

Mythlore: A Journal of J.R.R. Tolkien, C.S. Lewis, Charles Williams, and Mythopoeic Literature

Applies the philosophy of Georg Wilhelm Friedrich Hegel to The Violet Apple, a posthumously published novel by David Lindsay, whose A Voyage to Arcturus is frequently cited as an influence on Lewis’s Out of the Silent Planet.

Motoneuron Excitability Dysfunction In Als: Pseudo-Mystery Or Authentic Conundrum?, Sherif M. Elbasiouny

Neuroscience, Cell Biology & Physiology Faculty Publications

In amyotrophic lateral sclerosis (ALS), abnormalities in motoneuronal excitability are seen in early pathogenesis and throughout disease progression. Fully understanding motoneuron excitability dysfunction may lead to more effective treatments. Yet decades of research have not produced consensus on the nature, role or underlying mechanisms of motoneuron excitability dysfunction in ALS. For example, contrary to Ca excitotoxicity theory, predictions of motoneuronal hyper-excitability, normal and hypo-excitability have also been seen at various disease stages and in multiple ALS lines. Accordingly, motoneuron excitability dysfunction in ALS is a disputed topic in the field. Specifically, the form (hyper, hypo or unchanged) and what role …

Associations Between Faculty Vitality And Burnout In The Covid-19 Era: The Experience Of One Institution, Megan Ferriby Ferber, Tina H. Chen, Patrice L. Vallot, Jane Mchowat, Cindy C. Bitter

Journal of Wellness

Introduction: Faculty vitality is the ideal synergy between engaged faculty and mission-driven institutions that generates a fruitful environment for academic productivity, career satisfaction, and fulfillment of shared goals. The COVID-19 pandemic has introduced unprecedented disruptions to faculty vitality, with profound perturbations to individual and institutional support networks. However, the extent of this impact is unclear, as are strategies to mitigate loss of faculty vitality and prevent burnout.

Methods: We developed a survey instrument to evaluate the impact of COVID-19 on faculty vitality and burnout at a mid-sized, Midwestern academic institution affiliated with a university hospital. Survey items focused on individual …

The Donkey: An Unsung Hero Of Human Civilization, Andrew Rowan

Tales of WellBeing

Donkeys receive little respect but provide critical support and livelihood for millions of people worldwide.

Infrasonic Gliding Reflects A Rising Magma Column At Mount Etna (Italy), Mariangela Sciotto, Leighton M. Watson, Andrea Cannata, Massimo Cantarero, Emanuela De Beni, Jeffrey B. Johnson

Geosciences Faculty Publications and Presentations

Infrasound is increasing applied as a tool to investigate magma dynamics at active volcanoes, especially at open-vent volcanoes, such as Mt. Etna (Italy), which are prodigious sources of infrasound. Harmonic infrasound signals have been used to constrain crater dimensions and track the movement of magma within the shallow plumbing system. This study interprets the remarkable systematic change in monotonic infrasound signals preceding a lava fountaining episode at Mt. Etna on 20 February 2021. We model the changing tones (0.7 to 3 Hz fundamental frequency) as a rise in the magma column from 172 ± 25 m below the crater rim …

Major Niaid Grant Brings Cutting-Edge Equipment To Uab For Research On Covid And More, Matt Windsor

Browse All News

No abstract provided.

Daily Eastern News: October 19, 2022, Eastern Illinois University

October

No abstract provided.

What Motivates Barrier-Crossing Leadership?, Michael D. Buhrmester, Michael A. Cowan, Harvey Whitehouse

New England Journal of Public Policy

From large-scale wars, natural disasters, and pandemics to community-level religious and ethnic conflicts, many leaders wield power during crises by championing their group’s goals against those of rivals. But there is also a rarer breed of leader—barrier-crossers who pursue group interests by recognizing rivals’ interests and working with them to achieve mutually beneficial outcomes. Though such leaders have played vital roles in resolving conflicts, little is known about their extraordinary motivation. Here we report survey results contrasting barrier-crossing with barrier-bound leaders from seven communities. In line with new theories from group psychology and anthropology, we found that barrier-crossers uniquely reported …

A Latitudinal Signal In The Relationship Between Species Geographic Range Size And Climatic Niche Area, Tad Dallas, Andrew Kramer

Faculty Publications

Species with broader niches may have the opportunity to occupy larger geographic areas, assuming no limitations on dispersal and a relatively homogeneous environmental space. Here, we use data on a large set of mammal (n = 1225), bird (n = 1829) and tree (n = 341) species to examine the 1) relationship between geographic range size and climatic niche area, 2) influence of species traits on species departures from this relationship and 3) sensitivity of these relationships to how species range size and climatic niche area are estimated. We find positive geographic range size–climatic niche area relationships for all taxa, …

October 19, 2022 (Vol. 107, No. 9), Daily Eastern News

Daily Eastern News: 2022-2023

No abstract provided.

Household Salt Production By The Late Classic Maya: Underwater Excavations At Ta'ab Nuk Na, Heather Mckillop, E. Cory Sills

Faculty Publications

Salt is an essential commodity; archaeological remains around the world attest to the importance of its production, exchange and consumption. Often located in coastal locations, many production sites were submerged by rising seas, including the Paynes Creek Salt Works on the southern Belize coast. Survey and excavation of these sites has identified 'kitchens' for brine boiling, as well as Terminal Classic residential structures at Ek Way Nal. The authors report the discovery of an earlier residential building alongside salt kitchens at the nearby site of Ta'ab Nuk Na. This finding indicates that surplus household production began during the Late Classic, …

The Impact Of The Inclusion Of Grains In A Canine Diet On The Animal's Overall Health, Rachel Bruner

Honors Program: Senior Projects (Public)

The objective of this senior project was to examine the impacts that grains in a canine diet have on the overall health of the animal. Specifically, there was a focus on the nutritional attributes of grains, potential concerns regarding their inclusion in foods, misconceptions from consumers about grains in pet food, and alternatives to grains used in some diet formulations. The method of research for this project was a literature review. Scholarly articles focused on the various subtopics which helped to answer the research question were reviewed and included throughout the following discussion. Ultimately, the review of various literature resulted …