Digital Commons Network^™

Reclaiming Establishment: Identity And The ‘Religious Equality Problem’, Faraz Sanei

Law Faculty Scholarship

Since at least 2017, the Court has implicitly recognized a right of equal access to generally available public benefits based on the beneficiary's religious identity or status. In Carson v. Makin (2022), the Court went a step further and, for the first time, concluded that the “status-use distinction lacks a meaningful application” in both theory and practice. It then held that restrictions on the use of public benefits for sacral purposes amount to religious discrimination because they impose substantial burdens on free exercise rights. Carson's holding, and the rationale underlying it, contravene settled case law and effectively gut the Establishment …

It’S All Relative: Changes In Teachers’ Knowledge And Instruction During Covid-19, Daniel Mourlam, Daniel Decino, Steven R. Chesnut, Gabrielle Strouse, Ryan Los, Lisa Newland

School of Education Faculty Publications

In this convergent-parallel mixed-methods study, we explored the effect that teaching remotely during the first months of the pandemic had on teachers’ TPACK and how teachers leveraged their new and existing knowledge to facilitate remote instruction. Survey results indicated that teachers’ self-reported knowledge decreased across multiple TPACK subdomains, which is likely an indicator of teachers’ recalibration of their knowledge as they experienced a new instructional context. Findings from semi-structured interviews indicated that although instruction narrowed at times when teachers struggled to enact their knowledge in less-than-ideal circumstances, teachers were often able to successfully facilitate remote instruction.

Comparison Review Of The Production, Microbiology, And Sensory Profile Of Lambic And American Coolship Ales, John Carriglio, Drew Budner, Katherine A. Thompson-Witrick

Chemistry

Sour beers have been traditionally brewed with spontaneous fermentation. This has been occurring in Belgium for hundreds of years, and more recently in the United States as the American craft beer industry has boomed. Belgian sour styles include lambics, which are mirrored in a burgeoning style called the American coolship ale (ACA). American beers have much more creative leeway than their Belgian counterparts, as American craft brewing tends to incorporate more contemporary techniques and ingredients than their traditional European forebears. This review paper will summarize the history, production methods, fermentation, microbiological profiles, and sensory profiles of Belgian lambics and American …

Monte-Carlo Method Based Simulations For Photothermal Mucosa Coagulation With Accurate Depth Limits, Merve Türker Burhan, Serhat Tozburun

Turkish Journal of Electrical Engineering and Computer Sciences

The mucosa layer, the innermost layer of the gastrointestinal (GI) system, is of great importance in carcinogenesis since most cancerous tissues occur as superficial lesions. Although various treatment strategies exist, the main difficulty in eradicating lesions is unintentional damage to healthy tissues with the uncontrolled depth of treatment. This study proposes a computer modeling approach for simulating depth-resolved photothermal (laser) mucosal coagulation therapy. Computer modeling mimics the thermal dynamics of mucosal tissue to characterize the total heat energy required for successful superficial coagulation, which can be controlled by the scan rate, scan time, output power, and beam diameter of the …

Nebline, November/December 2022

NEBLINE Newsletter Archive from Nebraska Extension in Lancaster County

Holiday Wellness Tips by Alyssa Havlovic

Holiday Food Safety Quiz by Alyssa Havlovic

Recipe of the Month: Acorn Squash Cranberry Kale Salad by Alyssa Havlovic

Winter Protection for Potted Trees and Shrubs by Sarah Browning

Garden Guide: Things to Do This Month

What's the Deal With Smelly Well Water? by Becky Schuerman

Cover Crop Grazing Conference, Nov. 1

Pantry Pests by Kait Chapman

Bedtime Blues for Young Children by Hayley Jackson

Heart of 4-H Volunteer Award: Beatrice 77 Livestock and Lon and Carol Bohling

State 4-H Archery Outdoor Results

20 Years of Heart of 4-H Award!

4-H Announcements for Enrolled …

High-Resolution Ribosome Profiling Reveals Translational Selectivity For Transcripts In Bovine Preimplantation Embryo Development, Linkai Zhu, Tong Zhou, Rajan Iyyappan, Hao Ming, Michal Dvoran, Yinjuan Wang, Qi Chen, R. Michael Roberts, Andrej Susor, Zongliang Jiang

Faculty Publications

High-resolution ribosome fractionation and low-input ribosome profiling of bovine oocytes and preimplantation embryos has enabled us to define the translational landscapes of early embryo development at an unprecedented level. We analyzed the transcriptome and the polysome- and non-polysome-bound RNA profiles of bovine oocytes (germinal vesicle and metaphase II stages) and early embryos at the two-cell, eight-cell, morula and blastocyst stages, and revealed four modes of translational selectivity: (1) selective translation of non-abundant mRNAs; (2) active, but modest translation of a selection of highly expressed mRNAs; (3) translationally suppressed abundant to moderately abundant mRNAs; and (4) mRNAs associated specifically with monosomes. …

Modification Of The Tumor Microenvironment Enhances Anti-Pd-1 Immunotherapy In Metastatic Melanoma, Guilan Shi, Megan Scott, Cathryn G. Mangiamele, Richard Heller

Bioelectrics Publications

Resistance to checkpoint-blockade treatments is a challenge in the clinic. Both primary and acquired resistance have become major obstacles, greatly limiting the long-lasting effects and wide application of blockade therapy. Many patients with metastatic melanoma eventually require further therapy. The absence of T-cell infiltration to the tumor site is a well-accepted contributor limiting immune checkpoint inhibitor efficacy. In this study, we combined intratumoral injection of plasmid IL-12 with electrotransfer and anti-PD-1 in metastatic B16F10 melanoma tumor model to increase tumor-infiltrating lymphocytes and improve therapeutic efficacy. We showed that effective anti-tumor responses required a subset of tumor-infiltrating CD8⁺ and CD4 …

Ink (2022)

Ink, 2008-

The student-run features magazine covering the fashion, art, music and culture worlds at VCU and in Richmond. Published annually in print and updated regularly online.

Student Senate Meeting Minutes November 1, 2022, Student Senate-Winona State University

Student Senate Meeting Minutes

This document is the official Winona State University Student Senate Minutes November 1, 2022.

Third-Party Beneficiaries Of Government Contracts: Imagining An Equitable Approach And Applying It To Broken Promises In Detroit, Gabe Chess

Michigan Law Review

Courts have widely adopted a heightened standard for recognizing third-party beneficiaries of government contracts. But the justifications offered for the heightened standard do not withstand scrutiny. Instead, courts should apply a series of equitable factors to produce results consistent with the concern for “manifest justice” that animates third-party beneficiary doctrine. Governments make contracts frequently, often to address issues of huge importance to their citizens, including housing, economic development, and healthcare. In each of these areas, third-party beneficiary doctrine may be an important avenue of relief to citizens harmed by broken promises and may encourage the government and its contracting partners …

Practice Makes Professionalism, Virginia C. Thomas

Library Scholarly Publications

This column highlights three diverse examples of legal professionalism in our community.

The "Roaring Flame": Pursuing Thymos In Chinua Achebe's Things Fall Apart, Samrand Avestan, Owen G. Mordaunt

International Dialogue

Drawing principally from Francis Fukuyama’s (1952–) conception of thymos, this article focuses on exploring Okonkwo’s desire and his rigid personality in Chinua Achebe’s (1930–2013) magnum opus titled Things Fall Apart (1958). This paper hopes to prove how Achebe’s most famous character, Okonkwo, attempts to gratify his thymos which is described as a ‘desire for recognition’. Consistent with Fukuyama’s notion, this research examines how Okonkwo struggles to gain his thymos in confrontation with Ibo people and how his thymos-driven emotions incite him to reject the white colonists’ dominance in the fictional clan of Umuofia in Iboland. Therefore, we argue why Okonkwo’s …

Levinas, Adorno, And The Ethics Of The Material Other By Eric Nelson, Suny Press, 2020 Pp. 480, Emilia Angelova, Curtis Hutt, Leah Klmanson, Eric Nelson

International Dialogue

This is a number of reviews and responses to Eric S. Nelson's Levinas, Adorno, and the Ethics of Materials Other (2020) SUNY Press. This includes:

The Relation of the Ethics of the Material Other to the Rights of the Stranger by Emilia Angelova

Nelson's Defense of Asymmetrical Ethics: On Religion and Human Rights by Curtis Hutt

On Nelson and East Asian Philosophies by Leah Kalmanson

Author Response: The Ethics of the Material Other and the Right of the Other by Eric S. Nelson

Impacts Of Algal Morphology And Water Flow On Macroalgal Microplastic Capture, Cheyenne M. Adams

Honors College Theses

Microplastic pollution is a major area of concern in marine environments, especially as microplastics enter the food web. This study used pipe cleaners and two lichen species as algal mimics, and Chaetomorpha sp. and Chondrus crispus as model algal species to test the effects of morphology and biomass on microbead and foam capture. This study also utilized two different water flow methods: vortices and waves. Results suggest that water flow, as well as biomass and morphology, play a role in microplastic capture in macroalgae. For all mimics and algal species, except Cladonia lichens, turfs with increased biomass and length showed …

Regulation Of Tissue Mechanics And Adherens Junctions By Small Gtpase Rhoa During Drosophila Embryogenesis, Hanqing Guo

Dartmouth College Ph.D Dissertations

Actomyosin contractility plays an important role at both the cell and tissue level during developments. In this study, we developed an optogenetic tool that can acutely inhibit actomyosin contractility by targeting its main activator Rho1. This optogenetic tool can achieve myosin inhibition within one minute and thus enable further dissection of actomyosin function in development. In my first two projects, I used Drosophila mesoderm invagination (also known as ventral furrow formation) as a model to study epithelial folding, a fundamental mechanism for constructing complex 3D tissues. Apical constriction mediated by actomyosin contractility is a common mechanism for epithelial folding. However, …

Tephritid Fruit Fly Species Composition, Seasonality, And Fruit Infestations In Two Central African Agro-Ecological Zones, Samuel Nanga Nanga, Rachid Hanna, Apollin Fotso Kuate, Komi K.M. Fiaboe, Ibrahim Nchoutnji, Michel Ndjab, Désiré Gnanvossou, Samira A. Mohamed, Sunday Ekesi, Champlain Djieto-Lordon

All Peer-Reviewed Publications

Bactrocera dorsalis and several Africa-native Ceratitis species are serious constraints to fruit production in sub-Saharan Africa. A long-term trapping and fruit collection study was conducted (2011–2016) in two contrasting agro-ecological zones (AEZs) of Cameroon to determine fruit fly species composition, seasonality, attraction to various lures and baits, and fruit infestation levels. Ten tephritid species from genera Bactrocera, Ceratitis, Dacus, and Perilampsis were captured in traps. Bactrocera dorsalis was the most dominant of the trapped species and persisted throughout the year, with peak populations in May–June. Ceratitis spp. were less abundant than B. dorsalis, with Ceratitis anonae dominating in the western …

Algorithmic Governance From The Bottom Up, Hannah Bloch-Wehba

Faculty Scholarship

Artificial intelligence and machine learning are both a blessing and a curse for governance. In theory, algorithmic governance makes government more efficient, more accurate, and more fair. But the emergence of automation in governance also rests on public-private collaborations that expand both public and private power, aggravate transparency and accountability gaps, and create significant obstacles for those seeking algorithmic justice. In response, a nascent body of law proposes technocratic policy changes to foster algorithmic accountability, ethics, and transparency.

This Article examines an alternative vision of algorithmic governance, one advanced primarily by social and labor movements instead of technocrats and firms. …

Running On Empty: Ford V. Montana And The Folly Of Minimum Contacts, James P. George

Faculty Scholarship

Jurisdictional contests are in disarray. Criticisms date back to the issuance of International Shoe Co. v. Washington but the breakdown may be best illustrated in two recent Supreme Court opinions, the first rejecting California’s “sliding scale” that mixes general and specific contacts, the second using the discredited sliding scale to hold Ford amenable in states where accidents occurred.

California’s sliding scale is one variety of the contacts-relatedness tests, used in lower courts to have general contacts bolster weaker specific contacts. Some states—Montana and Minnesota for example—use the opposite extreme requiring a causal connection in defendant’s forum contacts, often using foreseeability …

Different Tides: A Journey Of Loss, Loneliness, And Friendship, William Gilmer

All Theses

This project is an exploration of story, producing an animatic for the original story Different Tides. Different Tides is a story about loss and separation, and how we carry with us a piece of everyone that has ever been close to us. This thesis will explore the themes of loneliness and loss that pervade the short, as well as the methods of visually expressing those themes. The goal of this thesis is to produce an animatable story, complete with storyboards, animatic, and color script, as well as explore the psychology behind loss and friendship.

Experimental And Observational Evidence Of Negative Conspecific Density Dependence In Temperate Extomycorrhizal Trees, Fiona V. Jevon, Dayna De La Cruz, Joseph A. Lamanna, Ashley K. Lang, David A. Orwig, Sydne Record, Paige V. Kouba, Matthew P. Ayres, Jaclyn H. Matthes

Biological Sciences Faculty Research and Publications

Conspecific negative density dependence (CNDD) promotes tree species diversity by reducing recruitment near conspecific adults due to biotic feedbacks from herbivores, pathogens, or competitors. While this process is well-described in tropical forests, tests of temperate tree species range from strong positive to strong negative density dependence. To explain this, several studies have suggested that tree species traits may help predict the strength and direction of density dependence: for example, ectomycorrhizal-associated tree species typically exhibit either positive or weaker negative conspecific density dependence. More generally, the strength of density dependence may be predictably related to other species-specific ecological attributes such as …

Post-Fire Seed Dispersal Of A Wind-Dispersed Shrub Declined With Distance To Seed Source, Yet Had High Levels Of Unexplained Variation, Cara Applestein, T. Trevor Caughlin, Matthew J. Germino

Biology Faculty Publications and Presentations

Plant-population recovery across large disturbance areas is often seed-limited. An understanding of seed dispersal patterns is fundamental for determining natural-regeneration potential. However, forecasting seed dispersal rates across heterogeneous landscapes remains a challenge. Our objectives were to determine (i) the landscape patterning of post-disturbance seed dispersal, and underlying sources of variation and the scale at which they operate, and (ii) how the natural seed dispersal patterns relate to a seed augmentation strategy. Vertical seed trapping experiments were replicated across 2 years and five burned and/or managed landscapes in sagebrush steppe. Multi-scale sampling and hierarchical Bayesian models were used to determine the …

Biodegradable Magnesium Materials Regulate Ros-Rns Balance In Pro-Inflammatory Macrophage Environment, Maria P. Kwesiga, Amani A. Gillette, Fatemeh Razaviamri, Margaret E. Plank, Alexia L. Canull, Zachary Alesch, Weilue He, Bruce P. Lee, Roger J. Guillory Ii

Peer Reviewed Articles

The relationship between reactive oxygen and nitrogen species (ROS-RNS) secretion and the concomitant biocorrosion of degradable magnesium (Mg) materials is poorly understood. We found that Mg foils implanted short term in vivo (24 h) displayed large amounts of proinflammatory F4/80+/iNOS + macrophages at the interface. We sought to investigate the interplay between biodegrading Mg materials (98.6% Mg, AZ31 & AZ61) and macrophages (RAW 264.7) stimulated with lipopolysaccharide (RAW 264.7^LPS) to induce ROS-RNS secretion. To test how these proinflammatory ROS-RNS secreting cells interact with Mg corrosion in vitro, Mg and AZ61 discs were suspended approximately 2 mm above a …

The Effect Of Covid- 19 Pandemic Process On Social Psychology And Nature-Based Therapeutic Activities, Aysun Yalvac, Esmahan Yalcin, Murad A. Kasalak

University of South Florida (USF) M3 Publishing

Today, many scientists have stated that the use of nature-based products and activities at certain rates together with the healing effect of modern medical techniques during the epidemic that affects the whole world has health-supporting benefits. Based on these views, people's consumption of products obtained from natural resources has increased and the interest in outdoor activities in nature has increased. Due to the positive effects of these activities on mental health, socialization and rehabilitation processes, over time, it became necessary to consider these activities within the scope of therapeutic recreation applied to groups with health restrictions such as the disabled, …

Safety Assessment Of Novel Foods And Food Proteins, Niloofar Moghadam Maragheh

Department of Food Science and Technology: Dissertations, Theses, and Student Research

The global food market needs to grow and supply food demand to feed the growing world population. Alternative food proteins, including novel sources of safe foods and ingredients, are the candidates that could provide more environmentally sustainable choices, animal welfare, and consumers health. Novel foods and food proteins must undergo premarket safety evaluations including allergenicity assessment to reduce the risk of cross-reactivity with known allergens and uncharacterized risk to food allergic individuals. This research addressed the safety assessment of some novel foods and food ingredients using the study of stability of proteins in pepsin and sequence identity analysis in the …

Identification Of Gut Microbiome Composition Responsible For Gas Production, Erasme Mutuyemungu

Department of Food Science and Technology: Dissertations, Theses, and Student Research

Gas production remains a significant barrier to increasing intake of dietary fiber-containing foods for many consumers. Therefore, this thesis is comprised of two studies focusing on the role of the gut microbiome in contributing to gas production during fermentation of dietary components. Previous studies have reported significant correlations between Megasphaera elsdenii and gas production during fermentation of pulses. Therefore, the objective of the first study was to determine the role of M. elsdenii in gas production by the microbiome during fermentation of foods commonly associated with gas production. Human fecal microbiomes were separated based on the presence (Me+) or absence …

Evaluation Of Wheat-Specific Peptide Targets For Use In The Development Of Elisa And Mass Spectrometry-Based Detection Methods, Jessica Humphrey

Department of Food Science and Technology: Dissertations, Theses, and Student Research

Individuals with IgE-mediated wheat allergy and celiac disease must avoid the consumption of wheat. Those with celiac disease must also avoid rye and barley in addition to wheat as these make up the gluten-containing grains. To ensure products are accurately labeled, ELISA methods may be used to monitor compliance with food allergen and gluten-free regulations. Currently, available ELISA methods for wheat detection utilize monoclonal antibodies that target peptides from the gluten fraction of proteins, and therefore, also detect rye and barley. Limitations such as differing antibody reactivity and unequal gluten content among wheat, rye, and barley have led to inconsistent …

Occurrence Of Hydroxyproline In Proteomes Of Higher Plants, Olivia Huffman

Department of Food Science and Technology: Dissertations, Theses, and Student Research

Food allergies affect millions of individuals across the United States and worldwide. Peanut allergies are among the most severe food allergies because of their potentially life-threatening symptoms and lifelong persistence. Potent peanut allergen, Ara h 2, is known to contain an amino acid motif containing the posttranslational modification, hydroxyproline (HyP). HyP is associated with immunogenic response when present both in Ara h 2 and in timothy grass pollen allergen, Phl p 1. To further explore the presence of HyP in higher plants and specifically to investigate its potential presence in commonly allergenic plants, a study of 26 plant seeds was …

Examining The Effects Of Formal Education Level On The Montreal Cognitive Assessment, Renee S. White, Justin M. Barber, Jordan P. Harp, Gregory A. Jicha

Sanders-Brown Center on Aging Faculty Publications

Background: Brief, global assessments such as the Montreal Cognitive Assessment (MoCA) are widely used in primary care for assessing cognition in older adults. Like other neuropsychological instruments, lower formal education can influence MoCA interpretation.

Methods: Data from 2 large studies of cognitive aging were used—Alzheimer’s Disease Neuroimaging Initiative (ADNI) and National Alzheimer’s Coordinating Center (NACC). Both use comprehensive examinations to determine cognitive status and have brain amyloid status for many participants. Mixed models were used to account for random variation due to data source.

Results: Cognitively intact participants with lower education (≤12 years) were more likely than …

Gold Nanoparticle (Aunp) As A Therapeutic Enhancer For Radio – And Immunotherapy Therapy Combination In Triple Negative Breast Cancer, Brana Janic, Stephen L. Brown, R. Neff, G. Mao, Indrin J. Chetty, Benjamin Movsas, Ning Wen

Radiation Oncology Meeting Abstracts

Purpose/Objective(s): Triple negative breast cancer (TNBC) is the most aggressive breast cancer (BC) form, with a high metastases rate and a very low survival. The aggressiveness of TNBC coupled with a significant toxicity and suboptimal chemotherapy outcomes underscores the urgency for new TNBC treatments. In recent years, immunotherapy has emerged as a promising option. In particular, immune checkpoint blockers (ICB) targeting PD-L1/PD1 inhibitory T cell check point pathway showed clinical responses and have been explored for TNBC. Unfortunately, the response rates to standalone ICB therapy are low (15-20%), indicating the presence of inhibitory immune mechanisms. Radiation therapy (RT) has been …

An Unsupervised Autoencoder Developed From Dynamic Contrast-Enhanced (Dce)-Mri Datasets For Classification Of Acute Tumor Response In An Animal Model, Hassan Bagher-Ebadian, Tavarekere N. Nagaraja, Glauber Cabral, Katelynn G. Farmer, Olivia Valadie, P. Acharya, Benjamin Movsas, Stephen L. Brown, Indrin J. Chetty, James R. Ewing

Radiation Oncology Meeting Abstracts

Purpose/Objective(s): Recent studies have shown that vascular parameters of brain tumors derived from DCE-MRI may act as potential biomarkers for radiation-induced acute effects. However, accurate characterization of the spatial regions affected by radiation therapy (RT) remains challenging. Here, we introduce an unsupervised adaptive model for classification and ranking of the RT-affected regions in an animal model of cerebral U-251n tumors.

Materials/Methods: Twenty-three immune-compromised-RNU rats were implanted with human U251n cancer cells to form an orthotopic glioma (IACUC #1509). For each rat, 28 days after implantation, two DCE-MRI studies (Dual Gradient Echo, DGE, FOV: 32 × 32 mm2, TR/(TE1-TE2) = 24 …