Digital Commons Network^™

The Outcomes Of Using Thai Biphasic Calcium Phosphate For Bone Augmentation In Implant Dentistry, Sirida Arunjaroensuk

Chulalongkorn University Theses and Dissertations (Chula ETD)

Aims: The aim of this randomized, double-blind, clinical trial was to compare the stability of the horizontal dimensions (facial bone thickness) of augmented bone using Biphasic Calcium Phosphate (BCP) with hydroxyapatite/ β-tricalcium phosphate ratio of either 60/40 or 70/30. Materials and Methods: Sixty dental implants placed with contour augmentation in the esthetic zone were randomized to 60/40 BCP (n=30) or 70/30 BCP (n=30). Cone-Beam Computed Tomographic was used to assess facial bone thickness post-implantation and 6 months later at implant platform and 2, 4, and 6 mm apical to it. Results: The percentage of horizontal dimension reduction was 23.64%, 12.83%, …

Isolation And Characterization Of Bacteriophage Targeting Acute Hepatopancreatic Necrosis Disease-Causing Vibrio Parahaemolyticus, Khrongkhwan Thammatinna

Chulalongkorn University Theses and Dissertations (Chula ETD)

Vibrio parahaemolyticus causing Acute hepatopancreatic necrosis disease (VPAHPND) has been a major cause of serious shrimp aquaculture economic losses. Moreover, many isolates have exhibited the resistance of various antibiotic drugs. Most recently, bacteriophage or phage, the killer of bacteria, has been gaining interest as an alternative tool to prevent and control pathogens. In this study, we discovered two novel vibriophages - vibriophage Seahorse and vibriophage phiKT1024 – that target various strains of VPAHPND. vibriophage Seahorse and vibriophage phiKT1024 were assigned to the family Siphoviridae and Myoviridae, respectively. Based on the cut-off of genome size that is less than 200 kbp …

Development Of Paper-Based Electrochemical Immunosensor For Sars-Cov-2 Detection, Jutamas Jaewjaroenwatana

Chulalongkorn University Theses and Dissertations (Chula ETD)

This dissertation aimed to develop a simple and low-cost electrochemical sensing platform for detecting SAR-CoV-2 antigen. The proposed sensor combined the innovative disposable paper-based immunosensor and cost-effective plant-based anti-SARS-CoV-2 monoclonal antibody, extracted from Nicotiana benthamiana. The cellulose nanocrystal was modified on screen-printed graphene electrode to provide the COOH functional groups on electrode surface, leading to the high ability for antibody immobilization. The quantification of the presence receptor binding domain (RBD) spike protein of SARS-CoV-2 was performed using differential pulse voltammetry by monitoring the changing current of [Fe(CN)6]3-/4- redox solution. The current change of [Fe(CN)6]3-/4- before and after the presence of …

Development Of Diagnostic Methods And Epidermiology Of Tuberculosis In Free-Ranging Long-Tailed Macaque Macaca Fascicularis And Rhesus Macaque M. Mulatta In Thailand, Suthirote Meesawat

Chulalongkorn University Theses and Dissertations (Chula ETD)

Cross-species infectious disease transmission, especially between humans and wildlife, is increasing during the global warming. Tuberculosis (TB) is an air-borne infectious disease that can be transmitted from humans to non-human primates (NHPs), however, no report of TB prevalence in free ranging NHPs that highly interacted with humans in Thailand was published. Thus, this study was conducted and separated into 3 phases. Phase I, active TB in 1,836 free-ranging macaques including 6 rhesus (Macaca mulatta; Mm), 23 common long-tailed (M. fascicularis fascicularis; Mff), and 3 Burmese long-tailed (M. f. aurea; Mfa) macaque populations throughout Thailand was assesses. Monkeys were captured, anesthetized, …

Seek, Picture Insect, Google Lens: An Analysis Of Popular Insect Identification Apps Using Photos Of Realistic Quality, Morgan Manderfield

Department of Entomology: Distance Master of Science Projects

Photo-based identification apps for mobile devices have grown in popularity across many fields of organismal biology. While studies have shown that these apps show promise in fields such as botany and ornithology, there is much skepticism surrounding their accuracy and usefulness in entomology. While providing these apps with photos of high quality will undoubtedly lead to the highest accuracy rates, often users submit photos of average quality, e.g., in poor lighting, out of focus, from far away, etc. To quantify realistic accuracy rates of photo-based insect identification apps, this study analyzed three popular apps – Seek, Picture Insect, and Google …

“One Bug, Two Bug, Good Bug, Bad Bug”, Ivy Grob

Department of Entomology: Distance Master of Science Projects

Integrated Pest Management (IPM) is a holistic strategy for the management of pest species. It is a framework that relies on scientifically informed decisions to identify and remediate a pest problem in a way that minimizes harm to the environment, human health, and the economy (Dara, 2019). The term pest is broadly defined not just as a nuisance, but as any organism that has detrimental effects to a resource or public health and that exists at a population level that exceeds a threshold of economic damage. This encompasses invertebrates (such as insects, nematodes, and mites), vertebrates, plant pathogens, diseases, and …

Counting Butterflies In Yosemite: A Guide For Beginners, Christine Melvin

Department of Entomology: Distance Master of Science Projects

Entomology is the study of insects. Insects are the most numerous animal group on the planet and therefore the field of entomology is further divided based upon insect groups. Butterflies and Moths belong to the insect group Lepidoptera. An entomologist who studies butterflies and/or moths is called a Lepidopterist. Butterflies are a special group of insects because they are not only studied by entomologists, but they are also studied by people called citizen scientists. Citizen science is the casual participation in gathering of data about anything relating to science. Anyone who uses the app iNaturalist is a citizen scientist because …

Gc/Ms And Lc/Ms Approaches To Chemical Communication In Plants And Marine Cyanobacteria, Carolyn Keim

University of the Pacific Theses and Dissertations

Natural products are small organic compounds synthesized by living organisms including plants, animals, and microbes. These fall into one of two categories, primary metabolites are required for survival, but secondary metabolites usually play a more accessory role. Extracts from organisms have proven to be useful to humans throughout history. Prior to evidence-based western medicine practices, natural products were the only source of medicine and remain as a treatment source for underdeveloped nations. Today, natural products have either been approved by or have served as the template for many FDA approved drugs. Based on a survey of all FDA approved drugs …

A Populist World Order? Origins And Predictions, Michael Lee

Publications and Research

No abstract provided.

Art. 8.9 Ceta Investment And Regulatory Measures, Stefanie Schacherer

Research Collection Yong Pung How School Of Law

Article 8.9 CETA on “Investment and Regulatory Measures” is at the centre of continuous and vigorous debate on how to ensure a proper balance between private business interests and the prerogative of States to regulate public welfare issue. The concerns expressed in the debate on the right to regulate are well-known. International investment agreements (IIAs) came under criticism due to their substantive protection standards, whose language is perceived as lacking in precision; as a consequence, they deliver too little policy flexibility. The protection standards together with the investor-State dispute settlement (ISDS) system, moreover, afford high levels of discretion to the …

Performance Of Black Soldier Fly Frass Fertiliser On Maize (Zea Mays L.) Growth, Yield, Nutritional Quality, And Economic Returns, C. M. Tanga, D. Beesigamukama, M. Kassie, P. J. Egonyu, Changeh J. Ghemoh, Kiatoko Nkoba, S. Subramanian, A. O. Anyega, S. Ekesi

All Peer-Reviewed Publications

Although the black soldier fly frass fertiliser (BSFFF) is globally recognised as a promising and potential high-quality organic fertiliser, there is inadequate information on its impact on the growth performance and nutritional status of maize. Furthermore, no information exist on their combination with mineral fertiliser (NPK) as well as economic impact on maize production. This study evaluated the comparative impact of BSFFF, NPK and commercial organic fertiliser (Evergrow®) on growth, nitrogen use efficiency, yield, nutritional quality, and profitability of maize under greenhouse conditions. The treatments included: (1) sole application of BSFFF, conventional compost of brewers’ spent grain (BSG), Evergrow, and …

Engineered Cord Blood Megakaryocytes Evade Killing By Allogeneic T-Cells For Refractory Thrombocytopenia, Bijender Kumar, Vahid Afshar-Kharghan, Mayela Mendt, Robert Sackstein, Mark R Tanner, Uday Popat, Jeremy Ramdial, May Daher, Juan Jimenez, Rafet Basar, Luciana Melo Garcia, Mayra Shanley, Mecit Kaplan, Xinhai Wan, Vandana Nandivada, Francia Reyes Silva, Vernikka Woods, April Gilbert, Ricardo Gonzalez-Delgado, Sunil Acharya, Paul Lin, Hind Rafei, Pinaki Prosad Banerjee, Elizabeth J Shpall

Faculty, Staff and Student Publications

The current global platelet supply is often insufficient to meet all the transfusion needs of patients, in particular for those with alloimmune thrombocytopenia. To address this issue, we have developed a strategy employing a combination of approaches to achieve more efficient production of functional megakaryocytes (MKs) and platelets collected from cord blood (CB)-derived CD34+ hematopoietic cells. This strategy is based on ex-vivo expansion and differentiation of MKs in the presence of bone marrow niche-mimicking mesenchymal stem cells (MSCs), together with two other key components: (1) To enhance MK polyploidization, we used the potent pharmacological Rho-associated coiled-coil kinase (ROCK) inhibitor, KD045, …

A Comparative Test Of Creative Thinking In Preschool Children And Dolphins, Dawn Melzer, Deirdre Yeater, Madison Bradley, Heather M. Hill, Gonzalo Guerra, Kimberly Salazar, Teresa Bolton, Kathleen M. Dudzinski

Psychology Faculty Publications

Creativity is considered one aspect of intelligence. Including creativity allows for more room for expression (e.g., participants can respond with movement instead of written or verbal responses) than in standard intelligence assessments. The Torrance Tests of Creative Thinking (TTCT; Torrance, 1974) are the leading method of assessing creative abilities in school-aged humans and above. To assess creativity in young humans and nonhuman animals, modifications must be made to facilitate nonverbal responses. In the current study, a cross-species comparison was conducted between preschoolers and bottlenose dolphins to examine responses to a modified creativity task in which both species were trained to …

Regenerative Medicine Technologies Applied To Transplant Medicine An Update, Astgik Petrosyan, Filippo Montali, Andrea Peloso, Antonio Citro, Lori N Byers, Catherine La Pointe, Mara Suleiman, Alice Marchetti, Eoin P Mcneill, Allison L Speer, Wai Hoe Ng, Xi Ren, Benedetta Bussolati, Laura Perin, Paolo Di Nardo, Vincenzo Cardinale, Jerome Duisit, Alexandra Rose Monetti, John Richard Savino, Amish Asthana, Giuseppe Orlando

Faculty, Staff and Student Publications

Regenerative medicine (RM) is changing how we think and practice transplant medicine. In regenerative medicine, the aim is to develop and employ methods to regenerate, restore or replace damaged/diseased tissues or organs. Regenerative medicine investigates using tools such as novel technologies or techniques, extracellular vesicles, cell-based therapies, and tissue-engineered constructs to design effective patient-specific treatments. This review illustrates current advancements in regenerative medicine that may pertain to transplant medicine. We highlight progress made and various tools designed and employed specifically for each tissue or organ, such as the kidney, heart, liver, lung, vasculature, gastrointestinal tract, and pancreas. By combing both …

Impairment Of Autophagy After Spinal Cord Injury Potentiates Neuroinflammation And Motor Function Deficit In Mice, Yun Li, Zhuofan Lei, Rodney M Ritzel, Junyun He, Hui Li, Harry M C Choi, Marta M Lipinski, Junfang Wu

Faculty, Staff and Student Publications

Autophagy is a catabolic process that degrades cytoplasmic constituents and organelles in the lysosome, thus serving an important role in cellular homeostasis and protection against insults. We previously reported that defects in autophagy contribute to neuronal cell damage in traumatic spinal cord injury (SCI). Recent data from other inflammatory models implicate autophagy in regulation of immune and inflammatory responses, with low levels of autophagic flux associated with pro-inflammatory phenotypes. In the present study, we examined the effects of genetically or pharmacologically manipulating autophagy on posttraumatic neuroinflammation and motor function after SCI in mice.

Methods: Young adult male C57BL/6, CX3CR1-GFP, autophagy …

Mechanisms And Treatment Of Pain-Depressed Behavior In Male And Female Mice, Clare M. Diester

Theses and Dissertations

One of the largest discrepancies between preclinical and clinical assessment of pain and analgesia is the type of behavioral endpoint used. Although most preclinical research has historically focused on drug effectiveness to block reflexive withdrawal behaviors stimulated by a noxious stimulus, increasing evidence shows that drug-induced restoration of pain-depressed behaviors provides increased clinical translation with decreased susceptibility to false-positives. Accordingly, the first portion of this dissertation designed a behavioral battery that featured pain-depressed behaviors as well as more conventional pain-stimulated behaviors for testing candidate analgesics in male and female mice. The main findings are as follows. (1) Intraperitoneal injection of …

Therapeutic Approaches For Respiratory Distress Syndrome, Franck J. Kamga Gninzeko

Theses and Dissertations

Respiratory distress syndrome (RDS) is characterized by shortness of breath and low oxygen levels. RDS affects the neonatal and adult populations. In the neonatal population, RDS can be classified as NRDS (Neonatal respiratory distress syndrome), while in adults, it is known as ARDS (acute respiratory distress syndrome). This dissertation examines a therapeutic approach to NRDS and a mechanistic approach to ARDS with in vivo and in vitro models of lung injury. NRDS is characterized by a deficiency or lack of surfactant. Surfactant is an essential compound composed of phospholipids and proteins to prevent the lungs from collapsing. There are several …

Race, Weight, Gender And The Embodied (Odied, Odied) Consciousness Of Big-Bodied Black Women Educators: A Phenomenological Study, Kendra D. Johnson

Theses and Dissertations

Big-Bodied Black women in the United States have perpetually navigated the veritable dichotomy of being hyper-visible and invisible (Beauboeuf-Lafontant, 2003; Fleetwood, 2001; Strings, 2019). Fat Black female bodies have borne the burden of exaggerated tropes and exploitation throughout history, stripping them of their femininity and humanity and resulting in a unique form of objectification (Strings, 2019). Inconsistent messages about BBWs, their bodies, and their value in society have endured for generations. They have been essential in constructing the controlling images of Black womanhood in the U.S. (Collins, 2000). The controlling images all evoked thoughts about the suitability of Black women …

Roots And Webs And Nets And Branches And Bulletin Boards And Banners And Newsletters And Mutual Aid Text Threads And Kin And Caretakers And Porches And Poems Of Today And Spaces Of Survival, Lukaza Branfman-Verissimo

Theses and Dissertations

As I welcome Richmond, VA into my family, I find myself needing to make roots and webs and nets and branches that ground me, that place myself as a Black, queer, mixed race, artist, activist, educator, storyteller, and cultural worker in this city. I am called to the streets before I am called to my studio. I question what it means to be a part of an institution that is slowly eating this city up. I become a story collector. I need to know where I am and whose land I now call home.

Blast Zone, Eleanor M. Thorp

Theses and Dissertations

My works emphasize the animistic qualities of extracted or displaced stones. This paper will explore my practice in relationship to practices of image reading, and drawing images within images, particularly rocks. I will use traditions of landscape painting, geological study, and Persian image making to talk about displacement of materials and stones.. I will explain how viewers can be trapped inside of the rock and my use of pastels, rock mediums, colored pencils, and my fingers to build these rocky landscapes.

Graduate School's Transformative Awakening: An Arts-Based Autoethnography, Roxanne L. Brown

Theses and Dissertations

This is an autoethnographic journey of a 30-year veteran art teacher through graduate school during the 2016 presidential campaign, election, presidency, #MeToo movement, a global pandemic, Black Lives Matter (BLM), virtual teaching and grading during a pandemic. My narrative includes an account of my transformative academic, social, and personal experiences and how they have informed my teaching practice. They include a collection of visual representations I created during my graduate school journey.

The Abuse Liability Profile Of An Unflavored, Sucralose-Sweetened, Electronic Cigarette In Combustible Cigarette Smokers, Sarah F. Maloney

Theses and Dissertations

The purpose of this study was to examine the effects of sucralose and nicotine in otherwise unflavored PG/VG ECIG liquid solutions, via a 30-watt ECIG, using multiple measures predictive of abuse liability to provide a basic understanding of the effects of sweeteners and perceived sweetness on ECIG abuse liability in reference to combustible cigarettes. Fourteen dependent smokers completed five independent study sessions that were within-subject, Latin-square ordered, and were identical in regards to all aspects but the product used. In each session, participants were given either their own brand of cigarettes or one of the four ECIG conditions: 0 mg/mL …

Peri-Implantitis Incidence And Effect Of Supportive Periodontal Therapy On Outcomes: Retrospective Cohort Study, Michael Ha

Theses and Dissertations

Purpose: Management of peri-implantitis is becoming an increasing component of dental practice. Dental implants can develop peri-implantitis lesions which occur in a non‐linear and accelerating pattern compared to a gradual periodontitis lesion. It is crucial to diagnose and treat this disease early, or ideally prevent it. Contemporary implants have a rough surface texture which is difficult to properly decontaminate as a crucial component for treatment prognosis. Evidence on the long-term effects of Periodontal implant maintenance therapy (PIMT) on implants is limited. This study aims to investigate the effect of periodontal maintenance on peri-implant tissue health.

Methods: A retrospective chart review …

Improving College Students’ Views And Beliefs Relative To Mathematics: A Systematic Literature Review Followed By A Multiple Case Mixed Methods Exploration Of The Experiences That Underpin Community College Students’ Attitudes, Self-Efficacy, And Values In Mathematics, Marquita H. Sea

Theses and Dissertations

Mathematics is particularly important due to its relevance in our daily lives. It is a general requirement throughout schooling. Unfortunately, many students openly declare negative views/beliefs regarding math in their personal and academic lives. These in turn, negatively influence students’ achievement related behaviors and outcomes. First, a systematic literature review was conducted to determine what types of studies/initiatives have aimed to enhance students’ views/beliefs relative to mathematics, including domain general and specific perceptions of math as well as their judgements of who is successful in mathematics and if they themselves can be successful. Specifically, the review centered on the components …

Puddlefist, Dylan Ahern

Theses and Dissertations

This written thesis focuses on my MFA thesis exhibition, Puddlefist. It begins with an introduction to both the artworks and my artistic approach, then discusses the text Transcendental Black Metal by Hunter Hunt-Hendrix, which serves as a larger reference point for the work. The latter part of this written thesis is a narrative influenced by the convergence of the sculptures that comprise the exhibition. I consider it a form of endurance writing that exercises motifs of noise, mantra, and monotony. In the section entitled Puc and Yellow, NPC (non-playable character) dialogue from the video game Fallout: New Vegas is transcribed …

Cadent Diffusion: Permeating The Membrane, Isabella M. Kubo

Theses and Dissertations

cadent diffusion: permeating the membrane explores and documents KUBO's journey of cultivating a sustainable and curious artistic practice during their Master’s program in Richmond, Virginia (Powhatan Land) from the Fall of 2020 to the Spring of 2022.

KUBO's practice is the affirmation between life and change in an attempt to work along the forces of singularity; to free lines, scores, concepts, and events from structures that otherwise bind them.The cadent diffusion is the rhythm in this force. Or perhaps, it is the force itself.

Wet, Flowering, Dry, Caroline A. Minchew

Theses and Dissertations

Wet, flowering, dry is a series of photographic works that explore how vernal pools are a macrocosm for holding memory and a site of omnipresent solitude and decay. This installation distills an embodied and ephemeral experience of how we are grounded in a network of invisible connections with our surroundings. This network becomes evident through biological, historical, and field research conducted at the vernal pools for over a year. Through slow observation and consideration of how multiple stories of place can weave together into a larger parable, Wet, flowering, dry reveals how the life cycle of a vernal pool is …

Until Its Calmness Can Claim You, Gabrielle Mchugh

Theses and Dissertations

This is an invitation to pause //

This is an externalization of my inner landscape, a highlight of what I value in my everyday and what comprises my lexicon of a sacred space. The following is a journey of nets, quiet, the sacred, space, and the in-between; where I share research and questions that are the foundation for my thesis work, Until Its calmness can claim you.

// This is an invitation to find moments of quiet in the noise

Traumatic Brain Injury-Induced Changes Of Immune/Inflammatory Response In The Context Of Predisposition Of Alzheimer’S Disease, Alexandra Pedin

Theses and Dissertations

Alzheimer’s Disease (AD) is a progressive neurogenerative disease that affects millions globally. At this time there are no effective treatment options as the primary cause for AD is not fully understood. In addition to old age, genetic predisposition, and certain health conditions, traumatic brain injury (TBI) has been identified as a risk factor for AD. While the pathway that links TBI to AD is still largely unknown, the neuroinflammatory response to both conditions has been connected to the NLRP3 inflammasome. Due to its role in the innate immune system and proinflammatory cytokine mediation, the NLRP3 inflammasome could be a potential …

Dregs / Lessons From The Things Around Us, Juan-Manuel Pinzon

Theses and Dissertations

The writing in Lessons From the Things Around Us is in support of the work in my MFA thesis show, dregs. I detail the progression of my making and thinking over the last two years. I expand on the material and personal relationships that have manifested themselves in the work and influenced my approach to the things that surround me. Finally, I point to a more expansive definition of Craft, rooted in its material sensibilities, and the possibilities already present in the field that this definition creates.