Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Life Sciences (5186)
- Medicine and Health Sciences (4359)
- Arts and Humanities (3380)
- Social and Behavioral Sciences (2926)
- Physical Sciences and Mathematics (2069)
-
- Law (1780)
- Education (1517)
- Medical Specialties (1480)
- Medical Sciences (1382)
- Animal Sciences (1110)
- Engineering (1033)
- Biology (970)
- Environmental Sciences (727)
- Ecology and Evolutionary Biology (696)
- History (680)
- Psychology (645)
- Plant Sciences (616)
- Diseases (496)
- Public Health (495)
- Earth Sciences (484)
- Religion (476)
- Business (467)
- Agriculture (451)
- Oncology (450)
- Creative Writing (447)
- Sociology (442)
- Art and Design (418)
- Bioinformatics (418)
- English Language and Literature (399)
- Higher Education (395)
- Institution
-
- The Texas Medical Center Library (1076)
- University of Nebraska - Lincoln (869)
- Washington University School of Medicine (579)
- University of Kentucky (528)
- Brigham Young University (464)
-
- City University of New York (CUNY) (372)
- Louisiana State University (350)
- University of Arkansas, Fayetteville (347)
- Utah State University (346)
- Chulalongkorn University (340)
- University of Central Florida (313)
- TÜBİTAK (290)
- University of Florida Levin College of Law (282)
- University of South Florida (282)
- University of Plymouth (280)
- University of New Hampshire (278)
- University of Montana (273)
- University of Mississippi (264)
- University of South Carolina (210)
- Nova Southeastern University (205)
- Thomas Jefferson University (203)
- University of Texas Rio Grande Valley (203)
- Yale University (201)
- Clemson University (190)
- Liberty University (178)
- Portland State University (177)
- San Jose State University (176)
- South Dakota State University (171)
- University of Memphis (159)
- Technological University Dublin (153)
- Keyword
-
- Animals (1036)
- Humans (892)
- Mice (690)
- COVID-19 (365)
- Female (246)
-
- Male (163)
- Climate change (157)
- Inflammation (121)
- ICTS (Institute of Clinical and Translational Sciences) (116)
- Education (109)
- SARS-CoV-2 (100)
- Sustainability (95)
- Machine learning (93)
- Obesity (89)
- Conservation (87)
- Pandemic (87)
- Disease Models, Animal (86)
- Brain (83)
- Diet (81)
- Cancer (80)
- Aging (79)
- History (79)
- Tumor Microenvironment (78)
- Gender (76)
- Animal (73)
- Ecology (73)
- Pregnancy (73)
- Cell Line, Tumor (72)
- Environment (72)
- JMG (72)
- Publication
-
- Theses and Dissertations (704)
- Faculty, Staff and Student Publications (642)
- 2020-Current year OA Pubs (426)
- Faculty Publications (316)
- Electronic Theses and Dissertations (304)
-
- Chulalongkorn University Theses and Dissertations (Chula ETD) (279)
- Faculty, Staff and Students Publications (275)
- IGC Proceedings (1977-2023) (247)
- Honors Theses (184)
- Florida Law Review (175)
- Theses (172)
- Dissertations (170)
- Florida Historical Quarterly (167)
- Faculty Scholarship (166)
- Open Access Publications (149)
- Masters Theses (148)
- Yale Graduate School of Arts and Sciences Dissertations (133)
- Children's Book and Media Review (130)
- Dissertations, Theses, and Capstone Projects (127)
- USF Tampa Graduate Theses and Dissertations (126)
- Master's Theses (123)
- Research outputs 2022 to 2026 (118)
- Graduate Theses and Dissertations (117)
- Articles (110)
- DRS Biennial Conference Series (101)
- Faculty Research 2022 (98)
- Turkish Journal of Veterinary & Animal Sciences (97)
- Graduate Theses, Dissertations, and Problem Reports (ETD) (95)
- Publications and Research (92)
- Walden Dissertations and Doctoral Studies (92)
- Publication Type
Articles 22741 - 22770 of 23558
Full-Text Articles in Entire DC Network
Typing Of Rarely Isolated Salmonella Serotypes With Mlst, Seyyi̇de Sariçam İnce, İnci̇ Başak Müştak, Hami̇t Kaan Müştak
Typing Of Rarely Isolated Salmonella Serotypes With Mlst, Seyyi̇de Sariçam İnce, İnci̇ Başak Müştak, Hami̇t Kaan Müştak
Turkish Journal of Veterinary & Animal Sciences
Salmonellosis caused by nontyphoidal Salmonella is the second most common zoonotic infection worldwide. The major foodborne route of this infection is the consumption of contaminated poultry meat and egg. Therefore, monitoring and control of Salmonella agents in poultry populations is critical to reduce the risks for public health. In the poultry industry, the most common serotypes in Salmonella infections are Salmonella enterica subsp. enterica serotype Enteritidis and Typhimurium. In recent years, other frequently isolated Salmonella serotypes have also increased in Turkey because of the Salmonella control programs regulated by many countries. Hence, other Salmonella serotypes (except for the most frequently …
Evidence-Based Information About Intermittent Fasting In Diabetes Patients: Useful Or Harmful?, Mustafa Altay
Evidence-Based Information About Intermittent Fasting In Diabetes Patients: Useful Or Harmful?, Mustafa Altay
Turkish Journal of Medical Sciences
Background/aim: One of the most important components of treatment for diabetic patients is diet and healthy nutrition therapy. Calorie restriction is effective and without cost increases its appeal for both patients and physicians. Unfortunately, continuous calorie restriction is a difficult method. For this reason, alternative calorie restriction methods, such as intermittent fasting (IF), have been investigated by some researchers. Materials and methods: IF refers to a wide range of diet programmes covering periods of eating and fasting, which vary according to the different regimens. In this article, first, some general information will enable us to understand the concept of IF, …
Optimal Screw Positioning In Cervical Pedicles To Avoid Complications, Kerem Atalar, Zafer Kutay Coşkun, Ahmet Memduh Kaymaz
Optimal Screw Positioning In Cervical Pedicles To Avoid Complications, Kerem Atalar, Zafer Kutay Coşkun, Ahmet Memduh Kaymaz
Turkish Journal of Medical Sciences
Background/aim: Cervical instability can be caused by a variety of factors, including trauma, tumors, or infection. The cervical transpedicular screw (CPS) is one of the most modern procedures for treating cervical instability. Despite the fact that numerous innovative techniques for CPS have been proposed, the appropriate screw entry points and screw directions have yet to be thoroughly established. The aim of this study is to determine the screw insertion angles and screw entry point distances based on reference points, pedicle axis lengths, and pedicle axis intersections for each vertebra from cervical (C) C2 to C7 in both right and left …
An Updated And Annotated Checklist Of The Malacostraca (Crustacea) Species Inhabitedturkish Inland Waters, Mehmet İpek, Murat Özbek
An Updated And Annotated Checklist Of The Malacostraca (Crustacea) Species Inhabitedturkish Inland Waters, Mehmet İpek, Murat Özbek
Turkish Journal of Zoology
The current status and annotated checklist of fresh- and brackish-water amphipod species inhabiting the inland waters (streams, lakes, ponds, lagoons, subterranean waters, etc.) of Turkey is presented. Totally, 171 papers, 3 books, 3 book chapters, 5 conference papers, 2 projects, 3 PhD and 3 MSc thesis were examined in the present study. As the result of the previous records, 201 taxa comprising 121 amphipods (16 families, 31 genera), 27 isopods (9 families, 13 genera), 9 mysids (1 family, 5 genera), 4 tanaids (3 families, 4 genera) and 40 decapods (16 families, 18 genera) were compiled. All the previously recorded localities …
Length-Weight Relationships Of 28 Fish Species Caught From Demersal Trawl Survey In Themiddle Black Sea, Turkey, Murat Dağteki̇n, Yaşar Genç, Nazli Kasapoğlu, Gökhan Eri̇k, Devri̇m Seli̇m Misir, Sali̇h İlhan, Meltem Ok, Cemi̇l Altuntaş, Uğur Özsandikçi, Ferhat Büyükdeveci̇, Tuğba Kaya, Ayşe Cebeci̇, Asi̇ye Nur Saltan, Ati̇la Haşi̇moğlu, Şi̇ri̇n Fi̇ri̇di̇n
Length-Weight Relationships Of 28 Fish Species Caught From Demersal Trawl Survey In Themiddle Black Sea, Turkey, Murat Dağteki̇n, Yaşar Genç, Nazli Kasapoğlu, Gökhan Eri̇k, Devri̇m Seli̇m Misir, Sali̇h İlhan, Meltem Ok, Cemi̇l Altuntaş, Uğur Özsandikçi, Ferhat Büyükdeveci̇, Tuğba Kaya, Ayşe Cebeci̇, Asi̇ye Nur Saltan, Ati̇la Haşi̇moğlu, Şi̇ri̇n Fi̇ri̇di̇n
Turkish Journal of Zoology
This study provides updated the length-weight relationships and Fulton's condition factor of 28 fish species belonging to 23 families from the Black Sea. Samples were collected along the depths between 0-100 meters by demersal trawl surveys conducted seasonally from May 2017 to September 2019. A total of 83,885 specimens were collected. The length-weight relationships and Fulton's condition factor, minimum, maximum and mean lengths, total weights, descriptive statistics, and growth type were provided for all the species. The results indicate that LWR parameters of b varied from 2.2039 to 3.737 and Fulton's condition factor varied between 0.004 and 1.18. These findings …
A Review Of The Alien Fishes Of Turkish Inland Waters, Erdoğan Çi̇çek, Soheil Eagderi, Sevi̇l Sungur
A Review Of The Alien Fishes Of Turkish Inland Waters, Erdoğan Çi̇çek, Soheil Eagderi, Sevi̇l Sungur
Turkish Journal of Zoology
Aquaculture, recreational fishing, restocking, biological control, and the ornamental fish trade have increased the number of nonnative fish in Turkish inland waters. This work reviews the history, current state, and tendencies of fish introductions into Turkish freshwaters. To date, it is known that a total of 34 exotic species (except two marine and three misidentified species) have been introduced deliberately or accidentally into Turkish inland waters, of which, only 19 species have been established in wild ecosystems. A total of five acclimatized species, viz. Coregonus lavaretus, C. macrophthalmus, Salmo salar, Salvelinus alpinus, and S. fontinalis and four species, viz. Hypophthalmichthys …
Surgical Outcomes Of Extraskeletal Myxoid Chondrosarcoma, Coşkun Ulucaköy, İsmai̇l Burak Atalay, Ali̇ekber Yapar, Ahmet Yi̇ği̇t Kaptan, İzzet Bi̇ngöl, Mehmet Doğan, Mehmet Fati̇h Ekşi̇oğlu
Surgical Outcomes Of Extraskeletal Myxoid Chondrosarcoma, Coşkun Ulucaköy, İsmai̇l Burak Atalay, Ali̇ekber Yapar, Ahmet Yi̇ği̇t Kaptan, İzzet Bi̇ngöl, Mehmet Doğan, Mehmet Fati̇h Ekşi̇oğlu
Turkish Journal of Medical Sciences
Background/aim: Extraskeletal myxoid chondrosarcoma (EMC) is a rare soft tissue sarcoma. The aim of this study is to present the results of the patients we treated with the diagnosis of EMC as an oncology reference center. Materials and methods: Information on 13 patients diagnosed with EMC between 2006 and 2018 was retrospectively reviewed. Patients' demographic information, tumor sizes, surgical treatments, chemotherapy and radiotherapy statuses, follow-up times, recurrences, and metastases were recorded. Results: Mean patient age was 53.6 ± 15 years (range: 28-73). In 8 patients, the tumor was located in the lower limbs, most commonly in the thigh (46.2%). Mean …
Marine Mucilage In The Sea Of Marmara And Its Effects On The Marine Ecosystem: Mass Deaths, Uğur Karadurmuş, Mustafa Sari
Marine Mucilage In The Sea Of Marmara And Its Effects On The Marine Ecosystem: Mass Deaths, Uğur Karadurmuş, Mustafa Sari
Turkish Journal of Zoology
In April of 2021, there was a massive explosion of marine mucilage in the Sea of Marmara, as a result, many invertebrates of marine communities suffered mass mortality. We summarize our results about the devastating effect of mucilage bloom on mass deaths in the Sea of Marmara. The phenomena were lethal to the pelagic fishes and crustaceans, and individuals were impacted severely smothered by mucilage or anoxia. Mucilage accumulations have shown their effectiveness in many areas around the Kapıdağ Peninsula. Misakça, Şirinçavuş, Narlı, and Tatlısu regions, where mass death cases occurred, were selected as study areas, and these areas are …
Factors Associated With Treatment Success After Combined Transforaminal Epidural Steroid Injection And Dorsal Root Ganglion Pulsed Radiofrequency Treatment In Patients With Chronic Lumbar Radicular Pain, Gülçi̇n Gazi̇oğlu Türkyilmaz
Factors Associated With Treatment Success After Combined Transforaminal Epidural Steroid Injection And Dorsal Root Ganglion Pulsed Radiofrequency Treatment In Patients With Chronic Lumbar Radicular Pain, Gülçi̇n Gazi̇oğlu Türkyilmaz
Turkish Journal of Medical Sciences
Background/aim: The aim of the study is to identify predictors of treatment success with combined transforaminal epidural steroid injection (TFESI) and dorsal root ganglion pulsed radiofrequency (DRG-PRF) in patients with lumbar radicular pain (LRP) associated with lumbar disc herniation. Materials and methods: The study included 48 patients with herniation-related LRP who underwent TFESI and DRG-PRF treatment between November 1, 2020 and April 30, 2021. Patient age, sex, symptom duration, history of lumbar surgery, and numeric rating scale (NRS) pain scores before and at 10 days, 1 month, and 3 months after treatment were evaluated retrospectively. Treatment success was defined as …
Earthworm Community Structure Along Altitudinal Gradients On The Western Slopes Ofkopaonik Mountain In Serbia, Filip Popovic, Mirjana Stojanovic, Slobodanka Radosavljevic, Tanja Trakic, Jovana Sekulic
Earthworm Community Structure Along Altitudinal Gradients On The Western Slopes Ofkopaonik Mountain In Serbia, Filip Popovic, Mirjana Stojanovic, Slobodanka Radosavljevic, Tanja Trakic, Jovana Sekulic
Turkish Journal of Zoology
The aim of this study is to examine the altitudinal patterns of earthworm community structure at different habitat types on the western slopes of Kopaonik Mountain. In total, 30 plots between 420 and 1950 m a.s.l. were sampled within two years' fieldwork. Overall, 27 earthworm taxa belonging to 11 genera were found at the study sites. A combination of Pearson's correlation, polynomial regression, and cluster analysis (UPGMA) was used for determining the effects of altitude on the earthworm community structure. The earthworm abundance and species richness monotonically decreased with the increase in altitude, showing a significant negative correlation. Cluster analysis …
Density, Diversity, And Seasonal Fluctuations In Soil Collembola In Three Differentlymanaged Ecosystems In North Khorasan, Iran, Mahmood Mehrafrooz Mayvan, Hussein Sadeghi Namaghi, Masoumeh Shayanmehr, Penelope Greenslade, Grant Palmer
Density, Diversity, And Seasonal Fluctuations In Soil Collembola In Three Differentlymanaged Ecosystems In North Khorasan, Iran, Mahmood Mehrafrooz Mayvan, Hussein Sadeghi Namaghi, Masoumeh Shayanmehr, Penelope Greenslade, Grant Palmer
Turkish Journal of Zoology
We examined the density, diversity, and seasonal fluctuation of soil inhabiting Collembola in different ecosystems: agricultural, rangeland, and forest ecosystems in the North Khorasan province of Iran from June 2018 to May 2019. The sampling program was conducted monthly on the three sites. Density was measured on the number of individuals per square meter. Species diversity was calculated using Shannon?Wiener index, Simpson?s diversity, and species richness by Rarefaction method. Fifty-three species belonging to 42 genera and 17 families were collected and identified. The density of Collembola in the forest was higher than in either rangeland or agroecosystem. Highest densities were …
Evolutionary Relationships Among Several Species From The Genus Cricotopus(Diptera: Chironomidae): What About Turkish Representatives Of This Genus?, Adi̇le Sari
Turkish Journal of Zoology
The genus Cricotopus (Diptera: Chironomidae) has a worldwide distribution and possesses a wide variation in ecology and habitat preference across its distribution. Identification of Cricotopus species and distinguishing them from the species of closely related genera (i.e. Orthocladius and Paratrichocladius) are generally difficult. This study aimed to investigate the evolutionary history of several Cricotopus species, with the main focus on C. bicinctus, C. flavocinctus, C. triannulatus, C. patens, C. intersectus, C. laricomalis, C. ornatus, C. reversus, and C. sylvestris from Turkey, using the mitochondrial cytochrome c oxidase subunit I (COI) gene. Molecular classifications of Turkish Cricotopus species were full compatible …
Hematological Status Of Avian Species Along A Metal Pollution Gradient At Sialkot, Pakistan, Ajmal Shehzad, Khalid Mahmood Anjum, Atif Yaqub, Muhammad Zubair Yousaf, Sarwr Allah Ditta, Junaid Naseer
Hematological Status Of Avian Species Along A Metal Pollution Gradient At Sialkot, Pakistan, Ajmal Shehzad, Khalid Mahmood Anjum, Atif Yaqub, Muhammad Zubair Yousaf, Sarwr Allah Ditta, Junaid Naseer
Turkish Journal of Zoology
The concentration of metals and effects of these metals on hematological parameters were examined in avian species by using feathers and blood samples collected from different sites of Sialkot. The major reason for significant differences in hematological parameters and concentrations of metal contents between different species was the difference in feeding habitat. Metal concentrations in feathers and blood samples indicated that the chromium and lead were not found at a safe level. The results did not revealed a significant negative association between metal contents and hematological parameters but concluded that increased metal contents exert negative effects on hematological status especially …
Egfr Blocker Lapatinib Inhibits The Synthesis Of Matrix Metalloproteinases From Synovial Fibroblasts, Demet Yalçin Kehri̇bar, Hakan Emmungi̇l, Neşe Başak Türkmen, Osman Çi̇ftçi̇, Emi̇ne Şalva, Meti̇n Özgen
Egfr Blocker Lapatinib Inhibits The Synthesis Of Matrix Metalloproteinases From Synovial Fibroblasts, Demet Yalçin Kehri̇bar, Hakan Emmungi̇l, Neşe Başak Türkmen, Osman Çi̇ftçi̇, Emi̇ne Şalva, Meti̇n Özgen
Turkish Journal of Medical Sciences
Background/aim: Epidermal growth factor receptor (EGFR) family members and their associated ligands may be related to bone and joint destruction in rheumatoid arthritis. Matrix metalloproteinases are responsible for joint and bone tissue degradation. This study is intended to investigate the effect of epidermal growth factor receptor inhibition by lapatinib on the synthesis of matrix metalloproteinases in in vitro. Materials and methods: Synovial fibroblast cell culture was obtained from a patient with rheumatoid arthritis who underwent knee arthroplasty. Interleukin-1ß (IL-1ß) and tumor necrosis factor-∝ (TNF-∝) were added to the cell culture to stimulate synovial fibroblast cells and create an inflammatory character. …
Alpha-Lipoic Acid Prevents Atrial Electrical And Structural Remodeling Via Inhibition Of Nadph Oxidase In A Rabbit Rapid Atrial Pacing Model, Lei Chen, Wen Gao, Yameng Shao, Chenggang Li, Yuan Lu
Alpha-Lipoic Acid Prevents Atrial Electrical And Structural Remodeling Via Inhibition Of Nadph Oxidase In A Rabbit Rapid Atrial Pacing Model, Lei Chen, Wen Gao, Yameng Shao, Chenggang Li, Yuan Lu
Turkish Journal of Medical Sciences
Background/aim: Alpha-lipoic acid (ALA) is a natural compound, one of the natural antioxidants with high activity. In the NADPH oxidase family, NADPH oxidase 4 (NOX4) is an important subunit participating in the production of ROS. NADPH oxidase 2 (NOX2) can form active NADPH oxidase complexes when binding to several other subunits in the cytoplasm, and NOX2 is its major functional subunit. Rapid atrial pacing (RAP) model was constructed to study the effects of ALA on electrical and structural remodeling in rabbits. Materials and methods: Thirty rabbits were divided into SHAM group, RAP group and ALA+RAP group. Their right atriums were …
Evaluation Of Toxic Effects Of Dapagliflozin On Reproductive System In Diabetic Rats, Bahar Karaca, Tuğçe Boran, Ayça Karagöz Köroğlu, Feri̇ha Ercan, Gül Özhan
Evaluation Of Toxic Effects Of Dapagliflozin On Reproductive System In Diabetic Rats, Bahar Karaca, Tuğçe Boran, Ayça Karagöz Köroğlu, Feri̇ha Ercan, Gül Özhan
Turkish Journal of Medical Sciences
Background/aim: Dapagliflozin (DAPA), sodium-glucose cotransporter 2 (SGLT2) inhibitor, is an insulin-independent antidiabetic drug used to control hyperglycaemia by promoting glucose excretion from the kidney. Its adverse effects include orthostatic hypotension, dehydration and urinary tract and genital infections caused by glycosuria. DAPA is subjected to constant additional monitoring, as drugrelated adverse reactions are frequently updated in line with the results of case studies, clinical trials and in vivo studies. Some antidiabetic drugs have shown potential harmful effects on the male reproductive system; however, the effects of DAPA have not been sufficiently studied in this capacity. Aiming to fill this gap in …
Interrupted Processing Of Paired Somatosensory Stimuli In Short Interstimulus Intervals: Role Of Thalamo-Cortical Oscillations, Nermi̇n Tepe, Hürrem Evren Boran, Sali̇h Geduk, Ergi̇n Di̇leköz, İlkay Ulusoy, Hayrunni̇sa Bolay Belen
Interrupted Processing Of Paired Somatosensory Stimuli In Short Interstimulus Intervals: Role Of Thalamo-Cortical Oscillations, Nermi̇n Tepe, Hürrem Evren Boran, Sali̇h Geduk, Ergi̇n Di̇leköz, İlkay Ulusoy, Hayrunni̇sa Bolay Belen
Turkish Journal of Medical Sciences
Background/aim: Discrimination of consecutive sensory stimuli is imperative for proper sensory perception and behavioral response. We aimed to investigate the emergence of paired somatosensory responses in relation to the interstimulus interval (ISI) change. Materials and methods: Paired stimulus with 35 ms, 50 ms, 80 ms, 140 ms, and 500 ms ISI was applied to the median nerve and evoked responses were recorded from the primary somatosensory cortex in rats. Early and late components of both responses were analyzed in different frequency bands. Results: The amplitudes were comparable for the 1st responses (S1), while the amplitude of the 2nd responses (S2), …
Effects Of Different Scar Types On Flap Viability In A Skin Flap Model: An Experimental Study, Ceyhun Uzun, Can İlker Demi̇r, Emrah Kağan Yaşar, Mehdi̇ Asadov, Murat Şahi̇n Alagöz, Esra Ci̇vri̇z, Çi̇ğdem Vural
Effects Of Different Scar Types On Flap Viability In A Skin Flap Model: An Experimental Study, Ceyhun Uzun, Can İlker Demi̇r, Emrah Kağan Yaşar, Mehdi̇ Asadov, Murat Şahi̇n Alagöz, Esra Ci̇vri̇z, Çi̇ğdem Vural
Turkish Journal of Medical Sciences
Background/aim: The purpose of this study was to investigate the use of tissues with multiple traumas, scarred pedicles, and medial scarring as a flap. Materials and methods: Forty-eight rats were randomly divided into four equal groups. The modified McFarlane flap was chosen as the flap model. In Group 1 (control), a dorsal skin flap was elevated and then sutured back into original position. In the other groups, a two-phase procedure was used. In Group 2 (pedicle incision), scar tissue was created with a skin incision at the prospective pedicle site of the flap and then sutured to its original site. …
Androgenic Hormones In Crustacean Aquaculture: A Review, Muzaffer Mustafa Harlioğlu, Ardavan Farhadi̇
Androgenic Hormones In Crustacean Aquaculture: A Review, Muzaffer Mustafa Harlioğlu, Ardavan Farhadi̇
Turkish Journal of Zoology
Increased demands of the seafood market have led to the rapid growth in crustacean aquaculture production in various parts of the world. Therefore, an expansion in the knowledge of the reproductive biology of crustaceans has become more important. Hormones released from the androgenic gland (AG) in crustaceans are liable for both the separation of primary and secondary sexual features and reproductive behavior. AG removal in male crustaceans causes a transformation of the intersex animals towards the females and a degeneration of spermatids and reproductive organs. AG implantation and injection of AG extracts are common approaches for crustacean masculinization. In this …
Complementary Medicines Used In Ulcerative Colitis And Unintended Interactions With Cytochrome P450-Dependent Drug-Metabolizing Enzymes, Alaatti̇n Şen
Complementary Medicines Used In Ulcerative Colitis And Unintended Interactions With Cytochrome P450-Dependent Drug-Metabolizing Enzymes, Alaatti̇n Şen
Turkish Journal of Medical Sciences
Ulcerative colitis (UC) is an idiopathic, chronic inflammatory disease with multiple genetic and a variety of environmental risk factors. Although current drugs significantly aid in controlling the disease, many people have led to the application of complementary therapies due to the common belief that they are natural and safe, as well as due to the consideration of the side effect of current drugs. Curcumin, cannabinoids, wheatgrass, Boswellia, wormwood and Aloe vera are among the most commonly used complementary medicines in UC. However, these treatments may have adverse and toxic effects due to unintended interactions with drugs or drugmetabolizing enzymes such …
Circulating Mir-200c And Mir-33a May Be Used As Biomarkers For Predicting High Fructose Corn Syrup-Induced Fatty Liver And Vitamin D Supplementation-Related Liver Changes, Alpaslan Tanoğlu, Eylem Çağiltay, Esra Güzel Tanoğlu, Ayli̇n Gökhan, Cansin Şi̇ri̇n, Türker Çavuşoğlu, Recep Soner Yeşi̇lbaş
Circulating Mir-200c And Mir-33a May Be Used As Biomarkers For Predicting High Fructose Corn Syrup-Induced Fatty Liver And Vitamin D Supplementation-Related Liver Changes, Alpaslan Tanoğlu, Eylem Çağiltay, Esra Güzel Tanoğlu, Ayli̇n Gökhan, Cansin Şi̇ri̇n, Türker Çavuşoğlu, Recep Soner Yeşi̇lbaş
Turkish Journal of Medical Sciences
Background/aim: Nonalcoholic fatty liver is one of the most common forms of liver disease and role of microRNAs (miRNAs) on this illness is currently unclear. It was aimed to evaluate the predictive role of circulating miR-33a and mir-200c on high fructose corn syrup (HFCS)-induced fatty liver and vitamin D3 supplementation-related hepatic changes. Materials and methods: Twenty-four rats were randomized into three groups: sham (n = 8), experimental fatty liver group (n = 8), and fatty liver + vitamin D3 supplementation group (n = 8). In the treatment group, 10 µg/kg/week of vitamin D3 was given by orogastric tube weekly for …
Impact Of Atp Synthase/Coupling Factor 6 In Hypoxic Pulmonary Arterial Hypertension: An Experimental Rat Model, Nannan Li, Yugen Shi, Jie Yin, Li Sun, Qingshan Zhang, Shuai Bao, Juan Zhang, Youlei Li, Miaomiao Wang, Yanwei Zhang, Mei Xue, Lei Qi, Yan Li, Suhua Yan, Xiaolu Li
Impact Of Atp Synthase/Coupling Factor 6 In Hypoxic Pulmonary Arterial Hypertension: An Experimental Rat Model, Nannan Li, Yugen Shi, Jie Yin, Li Sun, Qingshan Zhang, Shuai Bao, Juan Zhang, Youlei Li, Miaomiao Wang, Yanwei Zhang, Mei Xue, Lei Qi, Yan Li, Suhua Yan, Xiaolu Li
Turkish Journal of Medical Sciences
Background/aim: Hypoxia-induced pulmonary arterial hypertension (PAH) is characterized by prostacyclin (PGI2 ) disorder, which manifests in the same manner as in monocrotaline (MCT)-induced PAH. Endogenous PGI2 inhibitor coupling factor 6 (CF6) is involved in MCT-induced PAH. This study aimed to explore the presence or absence of a correlation between hypoxia-induced PAH and CF6. Materials and methods: This study was conducted between January 2019 and June 2020. A total of 135 male Wistar rats (aged 8 weeks and weighing 200?250 g) were randomly divided into five groups: (A) control, (B) 1 week of hypoxia, (C) 2 weeks of hypoxia, (D) 3 …
Dynamics Of A Western Anatolian Population Of Natrix Natrix And Natrix Tessellata(Serpentes: Natricidae), Yusuf Bayrakci, Di̇nçer Ayaz
Dynamics Of A Western Anatolian Population Of Natrix Natrix And Natrix Tessellata(Serpentes: Natricidae), Yusuf Bayrakci, Di̇nçer Ayaz
Turkish Journal of Zoology
Due to their secretive nature, snakes are the most challenging animal group for monitoring. Nevertheless, population size estimates are indispensable to accurately determining conservation status and management strategies. We used passive integrated transponder (PIT) tags to track aquatic snakes Natrix natrix and Natrix tessellata in Lake Işıklı, Denizli province, Turkey. 304 N. natrix and 1563 N. tessellata specimens were captured and marked over the four-year sampling period. Of the marked individuals, 14 N. natrix and 97 N. tessellata were recaptured at least once. The three-year average population size was estimated at 1940 ± 1055 for N. natrix, and 10,146 ± …
Comparison Of Anakinra And Tocilizumab In Management Of Severe Covid-19: A Retrospective Cohort Study, Orhan Küçükşahi̇n, Abdulsamet Erden, Özlem Karakaş, Serdar Can Güven, Berkan Armağan, Enes Seyda Şahi̇ner, Osman İnan, Ali̇ Can Kurti̇pek, Emi̇n Gemci̇oğlu, Selma Karaahmetoğlu, Sema Turan, Seval İzdeş, Deni̇z Erdem, Adalet Aypak, Müge Ayhan
Comparison Of Anakinra And Tocilizumab In Management Of Severe Covid-19: A Retrospective Cohort Study, Orhan Küçükşahi̇n, Abdulsamet Erden, Özlem Karakaş, Serdar Can Güven, Berkan Armağan, Enes Seyda Şahi̇ner, Osman İnan, Ali̇ Can Kurti̇pek, Emi̇n Gemci̇oğlu, Selma Karaahmetoğlu, Sema Turan, Seval İzdeş, Deni̇z Erdem, Adalet Aypak, Müge Ayhan
Turkish Journal of Medical Sciences
Background/aim: Studies regarding effectiveness of anakinra and tocilizumab treatments in coronavirus disease 2019 (COVID-19) have contradictory results. Furthermore, there is scarce comparative data regarding superiority of any agent. To further elucidate any superiority between these two agents, we retrospectively investigated and compared outcomes in hospitalized COVID-19 patients of our inpatient cohort who received anakinra or tocilizumab. Materials and methods: This study was designed as a single-center, retrospective, cross-sectional cohort study. Hospitalized patients with confirmed diagnosis of COVID-19 who had Brescia-COVID respiratory severity scale score ?3 and hyperinflammation (defined as elevation of C reactive protein ?50 g/L or ferritin ?700 ng/mL) …
What Is The Protective Effect Of Preischemic Kisspeptin-10 Administration Against Ischemia/Reperfusion Injury Of Striatum On Mice?, Hati̇ce Akkaya, Engi̇n Sümer, Seli̇m Kutlu, Hati̇ce Solak, Bayram Yilmaz
What Is The Protective Effect Of Preischemic Kisspeptin-10 Administration Against Ischemia/Reperfusion Injury Of Striatum On Mice?, Hati̇ce Akkaya, Engi̇n Sümer, Seli̇m Kutlu, Hati̇ce Solak, Bayram Yilmaz
Turkish Journal of Medical Sciences
Background/aim: Kisspeptin is a neuropeptide with a primary role on the onset of puberty and has beneficial effects on ischemia/ reperfusion (I/R) injury. In this study, we aimed to investigate the effect of kisspeptin administration on striatal I/R injury in mice. Material and methods: Forty adult C57/BL6 mice were randomly divided into four groups: Sham, Kisspeptin, I/R, and I/R + Kisspeptin groups. The groups were administered with either physiological saline (Sham and I/R groups) or kisspeptin (Kisspeptin and I/R + Kisspeptin groups) intraperitoneally 40 min before the operation. A microdialysis probe was placed in the right striatum according to stereotaxic …
The Relationship Between Hidradenitis Suppurativa And Irritable Bowel Syndrome: A Cross-Sectional Study, Abdullah Demi̇rbaş, Ömer Faruk Elmas, Hedi̇ye Eker, Gözde Ulutaş Demi̇rbaş, Recep Dursun, Mustafa Atasoy, Ümi̇t Türsen, Torello Lotti̇
The Relationship Between Hidradenitis Suppurativa And Irritable Bowel Syndrome: A Cross-Sectional Study, Abdullah Demi̇rbaş, Ömer Faruk Elmas, Hedi̇ye Eker, Gözde Ulutaş Demi̇rbaş, Recep Dursun, Mustafa Atasoy, Ümi̇t Türsen, Torello Lotti̇
Turkish Journal of Medical Sciences
Background/aim: Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder in which one experiences abdominal pain, tension, cramping, bloating, and changes in the form and frequency of defecation, without an underlying organic disease. Many skin diseases have been reported to be more common in people with functional bowel disease. To our knowledge, however, no previous study investigated the potential relationship between hidradenitis suppurativa (HS) and IBS. In this study, we aimed to examine the potential association between IBS and HS. Materials and methods: Patients with HS and healthy subjects were enrolled in this cross-sectional study. All participants were assessed for …
Investigation Of The Expression Levels Of Cdh1, Fhit, Pten, And Ttpal Genes In Colorectal Tumors, Evri̇m Suna Arikan Söylemez, Zafer Söylemez, Murat Çi̇lekar, Yüksel Arikan, Çi̇ğdem Tokyol, İbrahi̇m Hali̇l Kenger, Mustafa Solak
Investigation Of The Expression Levels Of Cdh1, Fhit, Pten, And Ttpal Genes In Colorectal Tumors, Evri̇m Suna Arikan Söylemez, Zafer Söylemez, Murat Çi̇lekar, Yüksel Arikan, Çi̇ğdem Tokyol, İbrahi̇m Hali̇l Kenger, Mustafa Solak
Turkish Journal of Medical Sciences
Background/aim: The main aim of the study is to assess expression levels of CDH1, FHIT, PTEN, and TTPAL genes in tumors and peripheral bloods of colorectal cancer patients in staged I-IV. Materials and methods: Gene expression analysis of related genes were performed for tumor tissues and peripheral blood samples of 51 colorectal cancer patients and colon tissues and blood samples of 5 healthy individuals. The real-time-PCR reaction method was used for the analysis. Results: Alteration of mRNA levels of related genes in tumor tissues of colorectal cancer cases was determined compared to control tissues. GAPDH and TBP were used for …
Developing The Nausea And Vomiting Thermometer Scale In Children With Cancer, Asli Akdeni̇z Kudubeş, Murat Bektaş
Developing The Nausea And Vomiting Thermometer Scale In Children With Cancer, Asli Akdeni̇z Kudubeş, Murat Bektaş
Turkish Journal of Medical Sciences
Background/aim: This study aimed to develop the Nausea and Vomiting Thermometer Scale (NVTS) in children with cancer. Materials and methods: This methodological study was conducted on 250 children with cancer at the research and training university hospital in Turkey between September 2019 and January 2020. The t-test, the ROC analysis, the Diagnostic index, and the Youden index were used for determining the scale of the cutting point. The regression analysis, the intra-class correlation coefficient, and the Bland- Altman analysis were used for the data analysis. Results: The scale-level content validity index was .94, which was coherent. As a result of …
Utility Of Etco2 To Predict Hemorrhagic Shock In Multiple Trauma Patients, Gülşen Öztürk Örmeci̇, Özlem Yi̇ği̇t, Oktay Eray
Utility Of Etco2 To Predict Hemorrhagic Shock In Multiple Trauma Patients, Gülşen Öztürk Örmeci̇, Özlem Yi̇ği̇t, Oktay Eray
Turkish Journal of Medical Sciences
Background/aim: For identifying hemorrhagic shock in trauma patients, some objective data are needed. The use of base excess (BE) and lactate values have been originated. In this study, it was aimed to determine the usability of end tidal carbon dioxide (ETCO2) in patients with multiple trauma for recognizing hemorrhagic shock. Materials and methods: Patients who were admitted to the emergency department between June 2019 and February 2020 with high- energy multiple trauma were included in the study. ETCO2 and BE values were measured. Correlation coefficients were calculated to determine correlations between ETCO2 and BE levels. Results: One hundred and twenty-two …