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2022

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Properties And Environmental Impacts Of Sustainable Electrically Conductive Composites Of Carbonized Pulp Fibers And Recycled Polyamide 12, Chinmoyee Das Jan 2022

Properties And Environmental Impacts Of Sustainable Electrically Conductive Composites Of Carbonized Pulp Fibers And Recycled Polyamide 12, Chinmoyee Das

Dissertations, Master's Theses and Master's Reports

Electrically conductive composites are polymer composites filled with electrically conductive filler. Electrically conductive composites can be implemented in the development of lightweight electrically conductive components for the automotive industry. Traditional electrically conductive composites incorporate synthetic carbon-based fillers that have good properties but are very expensive and highly energy intensive, creating the need for a sustainable and cost-effective replacement. This study explores the effectiveness of biocarbon fibers developed from Douglas fir pulp fibers as a potential electrically conductive filler in recycled polyamide (PA) 12 composites.

Biocarbon fibers were developed from pulp by carbonization of the feedstock at 1000° C in an …


Effects Of Dissimilar Silvicultural Techniques On Small Mammal Communities In Michigan's Upper Peninsula, Breanna R. Gusick Jan 2022

Effects Of Dissimilar Silvicultural Techniques On Small Mammal Communities In Michigan's Upper Peninsula, Breanna R. Gusick

Dissertations, Master's Theses and Master's Reports

Small mammal populations, and predators reliant upon them as food resources, are often challenged by conflicting objectives of timber production and maintenance of quality habitat. With over 70% of the landscape forested, and nearly one-third of the land privately owned, Michigan’s Upper Peninsula (UP) is a matrix of independent management strategies. To assess the effects of various silvicultural regeneration methods on small mammal populations in the Upper Peninsula, we trapped small mammals in experimental silviculture plots, whereby treatments varied by regeneration method (amount of residual canopy cover) and site preparation (i.e., control, tip-up, and scarification), and deer exclosures. We used …


Crude Extracts And Essential Oil Of Platycladus Orientalis (L.) Franco: A Source Of Phenolics With Antioxidant And Antibacterial Potential As Assessed Through A Chemometric Approach, Marwa Khammassi, Rayda Ben Ayed, Sana Khedhiri, Mouna Souihi, Mohsen Hanana, Ismail Amri, Lamia Hamrouni Jan 2022

Crude Extracts And Essential Oil Of Platycladus Orientalis (L.) Franco: A Source Of Phenolics With Antioxidant And Antibacterial Potential As Assessed Through A Chemometric Approach, Marwa Khammassi, Rayda Ben Ayed, Sana Khedhiri, Mouna Souihi, Mohsen Hanana, Ismail Amri, Lamia Hamrouni

Turkish Journal of Agriculture and Forestry

The chemical composition, antioxidant properties and antibacterial activities of different extracts (water, ethanol, acetate ethyl and hexane) and essential oil from Platycladus orientalis leaves were analysed in this study. The essential oil was extracted by hydrodistillation, and its chemical composition was determined by gas chromatography coupled to mass spectrometry (GC-MS). The major components of the essential oil were α-pinene (40.2%), β-phellandrene (9.3), α-cedrol (9.2%) and β-caryophyllene (6.3%). Phytochemical analysis of crude extracts and essential oil revealed the richness of ethyl acetate and ethanolic extracts in total phenolic content (62.69 and 61.44 mg GAE/g DW, respectively). The antioxidant activities of all …


Genome-Wide Analysis Of Peroxidase Genes In Passion Fruit (Passiflora Edulis Sims.) And Their Expression Patterns Induced By Root Colonization Of Piriformospora Indica Under Cold Stress, Dangdi Liang, Muhammad Moaaz Ali, Shariq Mahmood Alam, Xuping Huang, Ahmed Fathy Yousef, Walid F. A. Mosa, Emi̇ne Orhan, Zhimin Lin, Faxing Chen Jan 2022

Genome-Wide Analysis Of Peroxidase Genes In Passion Fruit (Passiflora Edulis Sims.) And Their Expression Patterns Induced By Root Colonization Of Piriformospora Indica Under Cold Stress, Dangdi Liang, Muhammad Moaaz Ali, Shariq Mahmood Alam, Xuping Huang, Ahmed Fathy Yousef, Walid F. A. Mosa, Emi̇ne Orhan, Zhimin Lin, Faxing Chen

Turkish Journal of Agriculture and Forestry

Peroxidases (PODs) have various physiological and biochemical roles in plant growth, development and stress response. The POD genes were identified in various plant species, but in passion fruit has not yet been thoroughly characterized. Here, we discovered 30 putative POD genes from the genome of Passiflora edulis Sims. For further elucidation, comprehensive bioinformatics analysis was utilized to determine the physicochemical properties, gene organization, conserved motifs, gene duplication and phylogenetic relationships of PePOD genes. Most of the POD proteins were predicted to be located in extracellular region. Gene organization and motif analysis showed that the number of exons and motifs in …


Selected Phenolics And Antioxidant Capacities: From Boğazkere (Vitis Vinifera L.) Grape To Pomace And Wine, Hande Tahmaz, Gökhan Söylemezoğlu Jan 2022

Selected Phenolics And Antioxidant Capacities: From Boğazkere (Vitis Vinifera L.) Grape To Pomace And Wine, Hande Tahmaz, Gökhan Söylemezoğlu

Turkish Journal of Agriculture and Forestry

In this research, the amounts of trans-resveratrol, (+)-catechin, (-)- epicatechin, and malvidin-3-glucoside which are among phenolic compounds as well as the total phenolic compound, total anthocyanin, and antioxidant capacity changes were examined in the Boğazkere (Vitis vinifera L.) grape, pomace before press, pomace after press and wine. In all parameters examined, a decrease was seen when proceeding from grape to wine, only (+)- catechin and (-)- epicatechin levels were detected to be higher in the prepress pomace. Total phenolic compound, total anthocyanin, and antioxidant capacity levels were found highest in grape samples, respectively, 8018 mg GAE/kg; 1606 mg/kg; 16.05 μmol …


Plant Growth-Promoting Bacteria Improve Triticum Aestivum L. Growth And Photosynthetic Activity In Sulfonamide-Contaminated Soil, Ammara Saleem, Asma Zulfiqar, Soha A. Alamoudi, Mada F. Ashkan, Eman Alhomaidi Jan 2022

Plant Growth-Promoting Bacteria Improve Triticum Aestivum L. Growth And Photosynthetic Activity In Sulfonamide-Contaminated Soil, Ammara Saleem, Asma Zulfiqar, Soha A. Alamoudi, Mada F. Ashkan, Eman Alhomaidi

Turkish Journal of Agriculture and Forestry

Antibiotics are disseminated by grazing animals or their feces throughout agricultural areas. These antibiotics, as environmental pollutants, have a negative impact on plant growth and physiology. Sulfonamides are frequently used to protect livestock production, but they also have a considerable negative impact on plant growth and rhizospheric bacteria. Plants are sensitive to their surroundings, and they employ their internal biological systems to deal with the threats to their growth and development. Soil microbes, which are the most common inhabitants, have amazing metabolic capacities that enable them to overcome abiotic constraints. The effects of sulfonamide stress on wheat cultivar Chakwal-50 were …


Amino Acids Application Alleviated Salinity Stress In Spinach (Spinacia Oleracea L.) By Improving Oxidative Defense, Osmolyte Accumulation, And Nutrient Balance, Maham Saddique, Abida Kausar, Iqra Iqra, Noreen Akhter, Nazoora Mujahid, Abida Parveen, Qamar Zaman, Saddam Hussain Jan 2022

Amino Acids Application Alleviated Salinity Stress In Spinach (Spinacia Oleracea L.) By Improving Oxidative Defense, Osmolyte Accumulation, And Nutrient Balance, Maham Saddique, Abida Kausar, Iqra Iqra, Noreen Akhter, Nazoora Mujahid, Abida Parveen, Qamar Zaman, Saddam Hussain

Turkish Journal of Agriculture and Forestry

Salinity is affecting more than 6 million hectares of cultivated area in Pakistan. The use of amino acids offers a pragmatic solution for minimizing the adverse effects of salinity on Spinacia oleracea L. (spinach). The present study evaluated the possible potential of amino acids in enhancing the salinity tolerance in spinach and identified the probable underlying mechanisms. The experiment comprised of two factors viz. amino acids with total of seven treatments; control, salinity (sal) 100 mM, Methionine + sal, Phenylalanine + sal, Proline + sal, Tyrosine + sal, Combined amino acids + sal, and two spinach cultivars (Desi Palak and …


Herbicide Resistance In Avena Sterilis Subsp Ludoviciana Populations From The Wheat Fields Of Turkey, Süleyman Gürdal Türkseven, Ahmet Uludağ, Mehmet Demi̇rci̇, Ahmet Tansel Seri̇m Jan 2022

Herbicide Resistance In Avena Sterilis Subsp Ludoviciana Populations From The Wheat Fields Of Turkey, Süleyman Gürdal Türkseven, Ahmet Uludağ, Mehmet Demi̇rci̇, Ahmet Tansel Seri̇m

Turkish Journal of Agriculture and Forestry

Avena sterilis L. subsp ludoviciana (Durieu) Gillet and Magne (AVELU) is among the most common and economically important grass weed species, especially in wheat fields of Turkey; therefore, the herbicides with the same mode of action (ACCase and ALS/AHAS inhibitors) are used to control have been successively applied without incessant by farmers. A study was conducted to find out the extent of wild oat problems throughout Turkey including herbicide resistance. This paper includes results of determining the herbicide resistance status of AVELU populations to ACCase and ALS inhibitors that are fenoxaprop (Fen), pinoxaden (Pin), tralkoxydim (Tra), mesosulfuron+iodosulfuron (MeI), and proxycarbazone+mesosulfuron …


Development Of Dna Markers Associated With Sunburn Resistance In Pomegranate (Punica Granatum L.) Using Bulk Segregant Analysis, Kezi̇ban Yazici, Mehtap Şahi̇n Çevi̇k Jan 2022

Development Of Dna Markers Associated With Sunburn Resistance In Pomegranate (Punica Granatum L.) Using Bulk Segregant Analysis, Kezi̇ban Yazici, Mehtap Şahi̇n Çevi̇k

Turkish Journal of Agriculture and Forestry

Production and consumption of pomegranate have been increasing in the world in recent years due to its health benefits to humans. Sunburn is an important physiological disorder caused by high temperature, light, and radiation. With the changes in climatic conditions that have occurred in recent years, the effect of sunburn is increasing and limiting the production and quality of pomegranate. Therefore, development of pomegranate cultivars resistance to sunburn is one of the main objectives of pomegranate breeding program. However, the development of a new variety takes a very long time. In order to shorten this time, molecular markers have been …


Unlocking The Genomic Regions Associated With Seed Protein Contents In Turkishcommon Bean Germplasm Through Genome-Wide Association Study, Faheem Shahzad Baloch, Muhammad Azhar Nadeem Jan 2022

Unlocking The Genomic Regions Associated With Seed Protein Contents In Turkishcommon Bean Germplasm Through Genome-Wide Association Study, Faheem Shahzad Baloch, Muhammad Azhar Nadeem

Turkish Journal of Agriculture and Forestry

Human body needs sufficient quantity of protein on daily basis for the normal functioning. Dietary protein in sufficient quantity is becoming a key issue for huge population of the world particularly in developing countries. Present investigation aimed to explore the phenotypic variation and to investigate the genomic regions associated with seed protein contents in Turkish common bean germplasm collected from 19 provinces. Field experiments were conducted according to augmented block design at two locations (Bolu and Sivas) for two consecutive years (2017 and 2018). Analysis of variance revealed highly significant environmental effects (p < 0.05) on seed protein contents within environments, while genotype by environment interaction revealed nonsignificant effects. Overall mean protein contents were 36.36%, while Balikesir-3 and Hakkari-38 yielded minimum (31.64%) and maximum (40.70%) protein contents. Among 19 provinces, accessions from Hakkari and Erzincan provinces disclosed maximum and minimum mean protein contents respectively. Scatter plot between seed protein contents and plant height divided the accessions according to their protein contents and plant height. A total of eight stable accessions were selected and can be recommended for future breeding activities. The implemented constellation plot separated the studied germplasm into two populations on the basis of their protein contents. Genotyping by sequencing resulted 7900 DArTseq markers was used for marker-trait association and a total of 11 markers showed significant association for protein contents. During this study, DArT-3365703 marker was identified in both locations (Sivas and Bolu) during 2017 and might be used for future common bean breeding. Physical map revealed the presence narrow regions between identified markers on Pv02 and Pv05. Therefore, these regions should be considered for future breeding activities. We are confident that results of present study will be helpful for marker-assisted breeding of common bean.


Research On The Potential Of Some Sweet Sorghum Genotypes As Bioethanol Source Undermediterranean Conditions, Celal Yücel, Derya Yücel, Rüştü Hati̇poğlu, Ismail Dweikat Jan 2022

Research On The Potential Of Some Sweet Sorghum Genotypes As Bioethanol Source Undermediterranean Conditions, Celal Yücel, Derya Yücel, Rüştü Hati̇poğlu, Ismail Dweikat

Turkish Journal of Agriculture and Forestry

Sweet sorghum (Sorghum bicolor var. saccharatum (L.) Mohlenbr.) is a variety of sorghum developed for the harvest of sweet juice, rather than grain. It has been identified as a potential ethanol feedstock crop for rainfed areas in different parts of the world. It is a promising source of bioenergy due to its high biomass, drought tolerance and low input. This study was conducted to determine the potential of bioethanol production from different sweet sorghum varieties under the Çukurova conditions with a Mediterranean climate. Experiments were conducted over two years in 2016 and 2017 on the experimental fields of the Eastern …


Induction Of Polyploidy In Grapevine (Vitis Vinifera L.) Seedlings By In Vivo Colchicineapplications, Zeki̇ Kara, Kevser Yazar Jan 2022

Induction Of Polyploidy In Grapevine (Vitis Vinifera L.) Seedlings By In Vivo Colchicineapplications, Zeki̇ Kara, Kevser Yazar

Turkish Journal of Agriculture and Forestry

Polyploidization is an important technique used in grape breeding to create new genetic resources and can be induced using some antimitotic agents, including colchicine. Plants with increased ploidy can gain better quality than their original diploids in some characteristics. In this study, which was carried out to obtain polyploid genotypes under in vivo conditions, the effects of six (1 g L-1, 2 g L-1, 3 g L-1, 4 g L-1, 5 g L-1, 6 g L-1) doses of colchicine were applied to the shoot tip meristem regions of the seedlings obtained from the seeds of grapevine cv. Ekşi Kara and …


Medicinal And Aromatic Plants In The Omics Era: Application Of Plant Breeding Andbiotechnology For Plant Secondary Metabolite Production, Muzaffer Barut, Muhammad Azhar Nadeem, Özlem Akgür, Leyla Sezen Tansi, Muhammad Aasim, Muhammad Tanveer Altaf, Faheem Shahzad Baloch Jan 2022

Medicinal And Aromatic Plants In The Omics Era: Application Of Plant Breeding Andbiotechnology For Plant Secondary Metabolite Production, Muzaffer Barut, Muhammad Azhar Nadeem, Özlem Akgür, Leyla Sezen Tansi, Muhammad Aasim, Muhammad Tanveer Altaf, Faheem Shahzad Baloch

Turkish Journal of Agriculture and Forestry

Human being has strong and historic connections with plants to fulfill food, feed, and shelter. Moreover, human uses plants as medicine for the treatment of various diseases. Plants are chemical factories for the biosynthesis of the huge number of secondary metabolites (SMs) that are directly used as a medicine or indirectly used in the development of commercial pharmaceutical drugs. Their improvement through classical breeding remains a difficult struggle for plant breeders. Hence, rapidly advancing research on the plant omics era has accelerated our understanding of the complex structure of SMs synthesis in medicinal and aromatic plants (MAPs). In addition, sequencing …


Inter-Primer Binding Site (Ipbs) Retrotransposon Markers Provide Insights Into Thegenetic Diversity And Population Structure Of Carrots (Daucus, Apiaceae), Mehtap Yildiz, Carlos Arbizu Jan 2022

Inter-Primer Binding Site (Ipbs) Retrotransposon Markers Provide Insights Into Thegenetic Diversity And Population Structure Of Carrots (Daucus, Apiaceae), Mehtap Yildiz, Carlos Arbizu

Turkish Journal of Agriculture and Forestry

Studies of genetic diversity and population structure are essential as an initial step in conservation and breeding programs for modern crops. Carrot (Daucus spp.) is among the ten most important vegetables worldwide, however, its genetic structure and phylogenetic relationships are not totally deciphered. Here, we explored the utility of 21 inter-primer binding site (iPBS) retrotransposon markers to determine the genetic diversity and population structure of 38 accessions of Daucus and one accession of a related genus. The manual scoring revealed 309 bands based on their presence/absence. The dendrogram based on the UPGMA clustering algorithm and a principal coordinate analysis (PCoA) …


Characterization Of Some Local Pea (Pisum Sativum L.) Genotypes For Agro-Morphologicaltraits And Mineral Concentrations, Aybegün Ton, Dürdane Mart, Tolga Karaköy, Meltem Türkeri̇, Ayfer Alkan Torun, Adem Emi̇n Anlarsal Jan 2022

Characterization Of Some Local Pea (Pisum Sativum L.) Genotypes For Agro-Morphologicaltraits And Mineral Concentrations, Aybegün Ton, Dürdane Mart, Tolga Karaköy, Meltem Türkeri̇, Ayfer Alkan Torun, Adem Emi̇n Anlarsal

Turkish Journal of Agriculture and Forestry

The aim of the present study is to evaluate diversity among the Turkish local pea germplasm for mineral concentrations and agro-morphological traits for breeding programs. The experiment was conducted during 2018/2019 and 2019/2020 and arranged according to an augmented block design with 40 local genotypes and two standard check cultivars (Carina and Jof). Seed yield per plant was positively and significantly correlated with branches per plant, pods per plant, seeds per pod, harvest index, and 100-seed weight. The first three principal components (PC1) for agro-morphological traits accounted for 76.3% of the total variation. The principal first component was positively correlated …


Study Of Anatomical And Acc (1-Aminocyclopropane-1-Carboxylate) During Flower Budabscission Indicate An Important Role Of Alternate Bearing, Muhammet Ali̇ Gündeşli̇, Sali̇h Kafkas, Şenay Karabiyik, Si̇nan Eti̇, Nesi̇be Ebru Kafkas Jan 2022

Study Of Anatomical And Acc (1-Aminocyclopropane-1-Carboxylate) During Flower Budabscission Indicate An Important Role Of Alternate Bearing, Muhammet Ali̇ Gündeşli̇, Sali̇h Kafkas, Şenay Karabiyik, Si̇nan Eti̇, Nesi̇be Ebru Kafkas

Turkish Journal of Agriculture and Forestry

This study investigates whether, and how, 1-aminocyclopropane-1-carboxylic acid (ACC) is concerned in flower bud abscission of pistachio (Pistacia vera L.). Abscission was studied about the activation of the abscission zone, located between shoot and flower bud, from Uzun pistachio cultivar where the abscission profiles and the scanning electron micrographs pictorial differences in the abscission program, under natural conditions of flower bud. ACC content was investigated in the flower bud abscission zone during growth and abscission using liquid chromatography coupled with electrospray tandem mass spectrometry (UPLC/ESI-MS/MS). Results showed that abscission layers were started at first 45 days after full blooming (DAFB) …


The Effects Of Zinc Oxide Nanoparticles Loaded With Iaa And Iba On In Vitro Rooting Ofapple Microcuttings, Shabnam Alizadeh, Hati̇ce Dumanoğlu Jan 2022

The Effects Of Zinc Oxide Nanoparticles Loaded With Iaa And Iba On In Vitro Rooting Ofapple Microcuttings, Shabnam Alizadeh, Hati̇ce Dumanoğlu

Turkish Journal of Agriculture and Forestry

In the micropropagation of difficult-to-root plants, the low rates of rooting cause high economic losses. The local apple (Malus domestica Borkh.) cultivar #67, which is highly resistant to fire blight disease, has been shown to have low rooting success. Nanoparticles loaded with auxins could increase the rooting success with their physicochemical properties. To increase rooting percentage, the effects of zinc oxide nanoparticles (nZnO), nZnO loaded with indole-3-acetic acid (IAA-nZnO) and indole-3-butyric acid (IBA-nZnO) at different concentrations (1.0, 2.0, 3.0, 4.0, 5.0, and 6.0 mg L-1) on in vitro rooting of microcuttings were investigated. The concentrations of auxin carried by the …


Rhetoric Of Surrogacy: Re-Considering Agency Through Embodied Performance, Ann Kitalong-Will Jan 2022

Rhetoric Of Surrogacy: Re-Considering Agency Through Embodied Performance, Ann Kitalong-Will

Dissertations, Master's Theses and Master's Reports

Surrogacy as a medical practice goes back, in a practical sense, to 1988, when the court case, “In the Matter of Baby M, A Pseudonym for an Actual Person,” was tried in the Supreme Court of New Jersey. At the heart of the issue, was the question of who Baby M’s legally-recognized mother was in the relationship between the contracting parents and the woman who gestated and gave birth to Baby M. Using this case as a jumping off point, this dissertation traces a history of surrogacy as a global industry. This project explores rhetorical agency in the embodied performance …


Defining The Endmember System Of Us Soils And Quantifying Relationships, And A Hyperspectral Approach To The Alteration Strength Index, Rachel Rulison Jan 2022

Defining The Endmember System Of Us Soils And Quantifying Relationships, And A Hyperspectral Approach To The Alteration Strength Index, Rachel Rulison

Dissertations, Master's Theses and Master's Reports

Soils form a complex part of the environment, providing important functions in systems such as food production, groundwater movement, and ecosystem health. There have been numerous studies on soil geochemistry and the origin of elements within soils, but few studies into quantifying the relationships between elements and geographical data on a national scale. Using geochemical data obtained by the USGS, the surficial soils of the US were defined by a 13-endmember system using Polytopic Vector Analysis and mapped in GIS. Correlation matrices provided Pearson’s correlation coefficients for elements in the Top 5 cm soil profile, the A horizon, and the …


Collective Hydrodynamics Of Robotic Fish, Rohit S. Pandhare Jan 2022

Collective Hydrodynamics Of Robotic Fish, Rohit S. Pandhare

Dissertations, Master's Theses and Master's Reports

Many animals in nature travel in groups either for protection, survival, or endurance. Among these, fish do so under the burden of hydrodynamic loads, which incites questions as to the significance of the multi-body fluid-mediated interactions that facilitate collective swimming. We study such interactions in the idealized setting of a rotational array of robotic fish whose tails undergo a prescribed flapping motion, but whose swimming speed is determined as a natural result of the hydrodynamic effects. Specifically, we examine how the measured collective speed of the swimmers varies with the imposed frequency and amplitude of their tail flapping, and with …


Rebuilding Fish-Human Relationships By Quantifying Combined Toxicity And Evaluating Policy Related To Legacy Contamination, Emily Shaw Jan 2022

Rebuilding Fish-Human Relationships By Quantifying Combined Toxicity And Evaluating Policy Related To Legacy Contamination, Emily Shaw

Dissertations, Master's Theses and Master's Reports

The central theme of this dissertation is relationships – building relationships as research partnerships, disrupting relationships through chemical contamination, and upholding existing relationships (i.e., responsibilities) to address industrial legacies. In partnership with the Keweenaw Bay Indian Community Lake Superior Band of Chippewa Indians (KBIC), this dissertation focuses on rebuilding fish-human relationships within the context of chemical contamination. By quantifying combined toxicity and evaluating the efficacy of cleaning up contamination, conclusions from this work help empower people to maintain practices and knowledges related to fish.

In chapter 1, I positioned myself, a white, American settler scholar, within the context of Indigenous …


Avian Haemosporidian Blood Parasite Diversity, Prevalence, And Distribution In Michigan’S Western Upper Peninsula, Maria M. Ferrer Jan 2022

Avian Haemosporidian Blood Parasite Diversity, Prevalence, And Distribution In Michigan’S Western Upper Peninsula, Maria M. Ferrer

Dissertations, Master's Theses and Master's Reports

Avian haemosporidian parasites, known as avian malaria (phylum Apicomplexa) can diminish an individual bird’s fitness by causing parasitemia, anemia, and reduced survival. Climate change is predicted to increase the spread of malarial parasites into more northerly latitudes where little is known about community compositions of these parasites. I assessed the prevalence and diversity of haemosporidian parasites in the first-ever community-level sampling of malaria in songbirds across the western Upper Peninsula of Michigan. In total, 179 blood samples were collected from birds representing 17 species, at five locations in the Upper Peninsula, including a mature forest, an early successional forest, and …


Isolation And Chromatographic Separation Of Cytotoxic Plant Compounds, Michael C. Hromada Jan 2022

Isolation And Chromatographic Separation Of Cytotoxic Plant Compounds, Michael C. Hromada

Dissertations, Master's Theses and Master's Reports

Plants produce diverse bioactive compounds that are used in the treatment of diseases such as cancer, microbial infection, and cardiovascular diseases. Our lab has discovered a potential anticancer compound named Hemolysin X (HelyX) in the storage and germination tissues of a plant species. Investigation of this compound relies on aqueous extraction which limits the isolation of other potentially important hydrophobic compounds. To overcome this limitation and to determine if HelyX is distributed in other tissues of the plant (such as flower), organic extracts of flower tissue were examined by analytical thin layer chromatography (TLC), preparative TLC, and silica gel column …


The Language Of Development In The Rhetoric Of Liberian Presidents, Tolulope Aina Odebunmi Jan 2022

The Language Of Development In The Rhetoric Of Liberian Presidents, Tolulope Aina Odebunmi

Dissertations, Master's Theses and Master's Reports

This dissertation contests the framing of “development” in Liberian presidential discourse — Inaugural and State of the Nation addresses of Ellen Johnson Sirleaf (EJS) and George Weah through Reisigl & Wodak's (2016) Discourse Historical Analysis (DHA) and conceptions of political ideologies (Chilton & Schaffner, 2002; van Dijk, 2006; Fairclough & Wodak, 1997). Aristotelian rhetoric complements my analysis. I turn to Mohanty (1988), Mama (2001), and other theorists of globalization for theorizing the subjectivity of third world subjects, setting up the complex connections between the periphery and global south. Through a linguistic, historical, and rhetorical analysis, I contest the framing and …


Evolutionary Conservation Of The Dream Subcomplex Muvb, Spencer Snider Jan 2022

Evolutionary Conservation Of The Dream Subcomplex Muvb, Spencer Snider

Dissertations, Master's Theses and Master's Reports

As the publications of annotated genomes from species representing most domains of life continue to grow exponentially, we are gaining more insight into how proteins, cellular pathways, and protein complexes evolved. We are interested in understanding how each protein in the 8-subunit transcriptional repressor complex called DREAM interacts with each other. DREAM is comprised of 3 main components: an E2F-DP transcription factor heterodimer, a pocket protein, and the highly conserved 5-subunit subcomplex called MuvB. We hypothesize that the mechanism of DREAM’s formation on chromatin dictates how DREAM functions to turn off target gene expression. Unfortunately, many interaction surfaces remain unknown, …


Display Site Selection By Male Ruffed Grouse In The Upper Great Lakes Region, Seth Finkel Jan 2022

Display Site Selection By Male Ruffed Grouse In The Upper Great Lakes Region, Seth Finkel

Dissertations, Master's Theses and Master's Reports

The Ruffed Grouse (Bonasa umbellus) is widely known for its characteristic territorial drumming display. In this study, I used ruffed grouse drumming survey data from Minnesota and Michigan, in a series of mixed logistic models, to identify drivers of drumming log selection by reproductive male ruffed grouse. I collected drumming stage data utilizing a paired-random sampling structure. I used information theoretic model selection to examine three sets of a priori mixed logistic models: one for the entirety of my Minnesota dataset, one consisting of stages identified in aspen stands in Minnesota, and one for my Michigan dataset. In …


An Antimicrobial Polydopamine Surface Coating To Reduce Biofouling On Telemetry Tags Used In Marine Conservation Practices, Ariana Smies Jan 2022

An Antimicrobial Polydopamine Surface Coating To Reduce Biofouling On Telemetry Tags Used In Marine Conservation Practices, Ariana Smies

Dissertations, Master's Theses and Master's Reports

Satellite telemetry tags are used to track the migration patterns of large cetaceans. These tags penetrate the dermis and remain embedded in the underlying blubber tissue. As the dermis of cetaceans is host to a diverse microbiome, and it is impossible to clean the skin before implanting the devices, the potential for infection is increased when the tags penetrate through the skin. H2O2 is a potential antimicrobial agent that, in addition to showing broad-spectrum efficacy against gram-negative and gram-positive bacteria, can promote wound healing outcomes by promoting proliferative factors and peptides that protect against oxidative stress. However, …


Beyond Homogenous Decision-Making Models: Role Of Brain Areas Interaction And Heterogeneity, Mohsen Rakhshan Jan 2022

Beyond Homogenous Decision-Making Models: Role Of Brain Areas Interaction And Heterogeneity, Mohsen Rakhshan

Dartmouth College Ph.D Dissertations

Most existing mechanistic models of decision making consider microcircuits within a homogenous brain area and fail to consider the distributed nature of this cognitive process. More specifically, these models do not take into account: a) how different types of information might influence choice in different stages of the process; and b) how interactions and the heterogeneity between circuits across different brain areas might be essential for the process. In this dissertation, I present a combination of experimental and modeling approaches to study distributed nature of the decision-making by examining both the distributed processing of information as well as the interaction …


Phase-Changing Nanodroplets As Nanotheranostic Platform For Combination Cancer Therapy, Catalina-Paula Spatarelu Jan 2022

Phase-Changing Nanodroplets As Nanotheranostic Platform For Combination Cancer Therapy, Catalina-Paula Spatarelu

Dartmouth College Ph.D Dissertations

Cancer is a cluster of diseases, and 1.8 million Americans are newly diagnosed each year. Treatment issues such as drug instability, the occurrence of severe side effects, as well as resistance make the need for solutions to improve conventional methods, like chemotherapy, apparent. Nano-sized drug-delivery platforms, particles loaded with therapeutic molecules that escape the immune system clearance and accumulate at the tumor site, were proposed as one of these solutions. Despite the expansion of the field, several aspects still need to be addressed: inconsistent delivery of the drugs, inability of measuring the effective dose being delivered to the tumor, lack …


In Situ Vaccination Using Plant Viral Particles As A Novel Approach For Cancer Immunotherapy, Chenkai Mao Jan 2022

In Situ Vaccination Using Plant Viral Particles As A Novel Approach For Cancer Immunotherapy, Chenkai Mao

Dartmouth College Ph.D Dissertations

Non-infectious to mammals, genetically, and physically stable plant virus-based nanoparticles have been increasingly studied as a novel platform for cancer vaccine and adjuvants due to their immunogenic properties. Our prior work showed that, empty cowpea mosaic virus (eCPMV), a plant virus-like particle (VLP) that is composed of a separated capsid, is an excellent in situ vaccine (ISV) for cancer immunotherapy; however, little is known about the mechanisms linked to their activities regarding recognition and antigen presentation.

In the present studies, we report cowpea mosaic virus (CPMV) and RNA-lacking CPMV (empty, eCPMV) are both toll like receptor (TLR) agonists for TLRs …