Digital Commons Network^™

Neurod1 Aav-Based Gene Therapy For Functional Brain Repair After Ischemic Injury Through In Vivo Astrocyte-To-Neuron Conversion, Marlena Ramlatchan

VCU's Medical Journal Club: The Work of Future Health Professionals

This study uses AAV based gene therapy to create an astrocyte- neuron conversion to regain functional abilities damaged by ischemic injuries. NeuroD1 treatment has shown promising results in the treatment of ischemic injuries in rodents and is heading towards clinical trials. Cognitive and motor improvements were shown. The basis of this therapy is to use functional glial cells to promote neurocellular growth, which would restore some function lost as a result of injury.

Regulation Of Genetically Engineered (Ge) Mosquitoes As A Public Health Tool: A Public Health Ethics Analysis, Zahra Meghani

Philosophy Faculty Publications

Background: In recent years, genetically engineered (GE) mosquitoes have been proposed as a public health measure against the high incidence of mosquito-borne diseases among the poor in regions of the global South. While uncertainties as well as risks for humans and ecosystems are entailed by the open-release of GE mosquitoes, a powerful global health governance non-state organization is funding the development of and advocating the use of those bio-technologies as public health tools.

In August 2016, the US Food and Drug Agency (FDA) approved the uncaged field trial of a GE Aedes aegypti mosquito in Key Haven, Florida. The …

2021 Touro University System Faculty Publications, Touro University System

Faculty Publications Books

2021 edition of the Faculty Publications Book of the Touro University system. This bibliography contains the published works of affiliated authors during 2021, arranged by academic unit.

2022-2023 Housing Resident Handbook, Morehead State University. Housing & Residence Education Office.

Housing & Residence Education Records

2022-2023 Housing Resident Handbook of Morehead State University.

Xenotransplants: The Risks And Benefits, Sima Langner

The Science Journal of the Lander College of Arts and Sciences

This literature review discusses how xenotransplants from animals, especially pigs, can serve as viable alternatives to allotransplants. There are many ways of ensuring the health of the host, including testing the donor pig for cytomegalovirus, Epstein Barr virus, simian agent 8, and other viruses linked to transmitted infections. The Galα-1,3-Gal epitope and N-glycolylneuraminic acid are both recognized by human antibodies and induce rejection. To remedy this, double knockout pigs have been developed that lack both. The human complement system serves as another potential pitfall for xenotransplants that can be neutralized by introducing human complement regulatory proteins into transgenic animals pre-transplant. …

Full Issue: Volume 16, Number 1, Fall 2022

The Science Journal of the Lander College of Arts and Sciences

Complete .pdf file of Volume 16, Number 1 of The Science Journal of the Lander College of Arts and Sciences. Published Fall 2022.

The Student Collective 2021-2022, The Student Collective

Yearbooks

Volume VIII

Yearbook from the 2021-2022 school year.

Southeastern Law Librarian Winter 2022, Seaall

Newsletters

No abstract provided.

Wash Practices In Mozambique, Karsyn Britsch

Ballard Brief

Although there has been improvement over the years, Mozambique severely lacks basic access to WaSH facilities. WaSH is a collective term for water, Sanitation and Hygiene - which refers to access to clean water, improved sanitation facilities, and basic hygiene materials like soap for handwashing. WaSH is an issue in Mozambique due to a declining number of natural water sources, a high amount of contaminated water resources, a lack of proper toileting facilities, and issues with governmental corruption hindering individuals from having access to clean water resources. These hindrances result in water-borne diseases. unsafe drinking water, bacteria ridden agriculture, and …

The Female Stigma: Menstruation Attitudes In The Women's Liberation Movement, Kayla Becknuss

AWE (A Woman’s Experience)

No abstract provided.

Ordinary And Extraordinary Images: Making Visible The Operations Of Stock Photography In Posters Against The Repeal Of The 8th Amendment, Ann Curran

Articles

The operations of stock photographs, as utilised by the Irish anti-abortion lobby, have not been examined before. Many of the ‘Vote No’ posters in the 2018 Irish referendum campaign on the 8th amendment maintained a visual and textual focus on foetal personhood: asking the Irish electorate to ‘love both,’ while deploying a range of stock photographs. In this article, I trace specific stock images used on anti-abortion posters against Repeal back to their online image bank sources. I make visible the role of generic or stereotypical photographs in anti-abortion messaging, in the knowledge that stock photographs often function best when …

A Relational Literary Geography Of George Macdonald’S The Wise Woman, John Pazdziora, James Thurgill

North Wind: A Journal of George MacDonald Studies

No abstract provided.

A Comparative Analysis Of The Andes And The Himalayas: How Climate Change Effects The Health Of Glaciers And The Social Impacts This Has On Surrounding Communities, Jacqueline Mountford

Environmental Studies Honors Papers

The glacial ice in both the Andean and Himalayan Mountain ranges act as water towers for the billions of people that live within their watersheds. Throughout the year, these communities rely on the glacial meltwater to increase the flow of rivers, but this meltwater is the most impactful during the dry season when there is less precipitation. Communities in both the Andes and Himalayas use this glacial meltwater for human and animal consumption, agricultural purposes, and harnessing hydroelectric power as a clean energy source. One of the biggest worries for scientists and people around the world is how climate change …

Reverse Engineering Spinal Motoneuron Properties In Slice And Whole-Cord Preparations Using Computational Modeling, Mohamed H. Mousa

Browse all Theses and Dissertations

Since Hodgkin and Huxley’s discoveries in the 1950s, mathematical modeling became an indispensable tool in neuroscience. The evolution of computer systems paved the way for computational models to improve our understanding of the nervous system. The long-term goals of this research are to develop tools for examining, understanding, and analyzing experimental data from spinal motoneurons (MNs), which are implicated in many motor disorders. Specifically, I developed high-fidelity, anatomically-detailed computational models that could be used to 1) study the cellular mechanisms underlying the non-linear MNs firing behaviors, 2) analyze the multifactorial process of MNs excitability regulation, and how it is affected …

Muhlenberg Magic, Lehigh Valley Health Network

LVHN documents

No abstract provided.

Multi-Temporal Monitoring Of Petroglyphs Using Sfm Photogrammetry, Aaron Estes

All-Inclusive List of Electronic Theses and Dissertations

This thesis describes the development and testing of an experimental method for monitoring the condition of archaeological features through computer-assisted 3D change detection. This method utilizes structure-from-motion (SfM) photogrammetry and the Model-to-Model Cloud Comparison (M3C2) algorithm to document and compare features in three dimensions. In collaboration with the Daniel Boone National Forest (DBNF) of eastern Kentucky, USA, this method was tested using a sample of nine ancient rock carvings, or petroglyphs, in hopes of identifying and tracking multiscale change. SfM photogrammetry is the process of creating 3D representations using 2D images, and the M3C2 algorithm measures the precise distance between …

Annual Reports For The Town Of Strafford, New Hampshire 2021, For The Year Ending December 31, 2021., Strafford Town Representatives

Strafford, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

Annual Report Woodstock, New Hampshire For The Fiscal Year Ending December 31, 2021., Woodstock Town Representatives

Woodstock, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

Annual Report Town Of Loudon, New Hampshire Annual Report For The Fiscal Year Ending June 30, 2022., Loudon Town Representatives

Loudon, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

Chapter 16. Holy Ghost College—Duquesne University 1878–1923

Spiritan Horizons

No abstract provided.

Expanding The Landscape Of Amino Acid-Rich Antimicrobial Peptides: Definition, Deployment In Nature, Implications For Peptide Design And Therapeutic Potential, Aaron P. Decker, Abraham F. Mechesso, Guangshun Wang

Journal Articles: Pathology and Microbiology

Unlike the α-helical and β-sheet antimicrobial peptides (AMPs), our knowledge on amino acid-rich AMPs is limited. This article conducts a systematic study of rich AMPs (>25%) from different life kingdoms based on the Antimicrobial Peptide Database (APD) using the program R. Of 3425 peptides, 724 rich AMPs were identified. Rich AMPs are more common in animals and bacteria than in plants. In different animal classes, a unique set of rich AMPs is deployed. While histidine, proline, and arginine-rich AMPs are abundant in mammals, alanine, glycine, and leucine-rich AMPs are common in amphibians. Ten amino acids (Ala, Cys, Gly, His, …

Town Of New Ipswich, Nh Annual Report For 2021., New Ipswich Town Representatives

New Ipswich, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

Annual Reports Of The Town Officers Town Of Stoddard, New Hampshire 2022, Fiscal Year Ending 2021., Stoddard Town Representatives

Stoddard, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

Town Of Dummer, Nh Annual Report Of The Town Officers For The Year Ended December 31, 2021, Dummer Town Representatives

Dummer, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

Sjsu Erfa News, Winter 2022, San Jose State University, Emeritus And Retired Faculty Association

Emeritus and Retired Faculty Association (ERFA) Newsletter

Volume 36, No 2

“Doe As Thou Wouldst Be Done By”: Relief Responses To Mental Illness In Puritan New England, Rebecca Farias

History & Classics Dissertations and Masters Theses

The emergent historical field of early American disability studies has catalyzed discussion on the mental and physical impairments that contributed to America’s cultural, medical, social, and economic foundations. How can historians tell an accurate story of mental illness, grounded in the narrative of America’s founding, and situate mental illness within disability studies? Literary and linguistic categories of analysis, presented in this thesis, can help historians begin to unpack disability in early modern New England.

The New England Puritan welfare model formed a basis of American disability ideology, a framework that persisted well until the 1800s. This article seeks to dispel …

Excluded From Our City: Clement Of Alexandria And The Porous Frontier Of Early Christian Identity, Jordan C. Goneau-Goncalves

Theology Graduate Theses

In the Paedagogus, the second volume of his three major works, Clement of Alexandria develops a “Christian” ethic and sense of identity, which is dependent on one’s “habits, deeds, and passions.”¹ The work itself is directed toward “you who are children” and is intended to instruct Christians in matters of character and behavior.² Though he is preoccupied with attempting to educate—rather, allowing his understanding of Christ to educate—Christians in regard to appropriate behaviors and values, thereby defining and maintaining a unique sense of Christian identity in late second century Alexandria, he is also at home in a …

Active Participation In The Two Direct Points Of Contact With God Within The Thomistic Metaphysics Of Human Nature, Richard. R. Palin Jr.

Theology Graduate Theses

No abstract provided.

Recommendations To Address Race In Washington’S Juvenile Legal System: 2022 Recommendations To Criminal Justice Stakeholders In Washington, Task Force 2.0: Race And The Criminal Justice System

Fred T. Korematsu Center for Law and Equality

Recommendations to Address Race in Washington’s Juvenile Legal System: 2022 Recommendations to Criminal Justice Stakeholders in Washington

Improving Dysarthric Speech Recognition By Enriching Training Datasets, Sophie Cullen

Dissertations

Dysarthria is a motor speech disorder that results from disruptions in the neuro-motor interface and is characterised by poor articulation of phonemes and hyper-nasality and is characteristically different from normal speech. Many modern automatic speech recognition systems focus on a narrow range of speech diversity therefore as a consequence of this they exclude a groups of speakers who deviate in aspects of gender, race, age and speech impairment when building training datasets. This study attempts to develop an automatic speech recognition system that deals with dysarthric speech with limited dysarthric speech data. Speech utterances collected from the TORGO database are …