Digital Commons Network^™

Attention-Deficit/Hyperactivity Disorder (Adhd) In Preschool-Aged Children: A Critical Review, Will Anastasiadis

Bakerman Student Research Awards

Attention-Deficit/Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder characterized by core symptoms of hyperactivity, impulsivity, and inattention (American Psychiatric Association, 2013). ADHD is a fairly common psychopathology diagnosed in childhood (Kooij et al., 2010; Perou et al., 2013). For instance, a recent study conducted by the Centers for Disease Control and Prevention (CDC) found that approximately 6.1 million (9.4%) U.S. children and adolescents between the ages of 2 and 17 have received an ADHD diagnosis; these prevalence estimates were acquired from a collection of 2016 parent-reported ADHD diagnoses (Danielson et al., 2018). Of those patients diagnosed with ADHD, a weighted estimate …

Viral Suppression Of Ripk1-Mediated Signaling, Darshika J. Udawatte, Alan L. Rothman

Cell and Molecular Biology Faculty Publications

Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) has emerged as a key upstream regulator of cell death and inflammation. RIPK1-mediated signaling governs the outcome of signaling pathways initiated by tumor necrosis factor receptor 1 (TNFR1), Toll-like receptor 3 (TLR3), TLR4, retinoic acid-inducible gene 1 (RIG-I)/melanoma differentiation-associated protein 5 (MDA-5), and Z-binding protein 1 (ZBP1) by signaling for NF-k B activation, mitogen-associated protein kinase (MAPK) and interferon regulatory factor 3/7 (IRF3/7) phosphorylation, and cell death via apoptosis and necroptosis. Both cell death and inflammatory responses play a major role in controlling virus infections. Therefore, viruses have evolved multifaceted mechanisms to exploit host immune …

Winter Cereal Rye Cover Crop Decreased Nitrous Oxide Emissions During Early Spring, Graig W. Reicks, David E. Clay, Sharon A. Clay, Deepak R. Joshi, Janet Moriles-Miller, Shaina Westhoff, Aaron Lee M. Daigh, Stephanie A. Bruggeman

Agronomy, Horticulture and Plant Science Faculty Publications

Despite differences between the cover crop growth and decomposition phases, few greenhouse gas (GHG) studies have separated these phases from each other. This study’s hypothesis was that a living cover crop reduces soil inorganic N concentrations and soil water, thereby reducing N₂O emissions. We quantified the effects of a fall-planted living cereal rye (Secale cereale L.) cover crop (2017, 2018, 2019) on the following spring’s soil temperature, soil water, water-filled porosity (WFP), inorganic N, and GHG (N₂O-N and CO₂–C) emissions and compared these measurements to bare soil. The experimental design was a randomized …

Data Analysis, Policies, And Practices Addressing Parental Incarceration And Behavioral Outcomes., Jennifer Wyatt Bourgeois

Dissertations (2016-Present)

• collateral consequences of incarceration
• parental arrest
• parental incarceration
• parental status

Hair Toxicology Testing Among Children Evaluated For Physical Abuse: Evaluation Of A Practice Change., Ashley Dejarnette

Doctor of Nursing Practice Papers

Background: Despite a complete medical evaluation for child physical abuse, many suspected victims have indeterminant findings. The lack of a definitive diagnosis can impede child protection agencies’ ability to protect those children at high risk for abuse, leaving them vulnerable to subsequent injuries and potentially escalating violence by caregivers. Oftentimes, allegations of child physical abuse are accompanied by concerns for substance abuse by the caregiver as well. While we know that children living in homes where caregivers use illicit substances are at substantially higher risk for physical abuse, drug testing children for environmental exposure to illicit substances is not yet …

Automated Parsing Of Flexible Molecular Systems Using Principal Component Analysis And K-Means Clustering Techniques, Matthew J. Nwerem

Computational and Data Sciences (MS) Theses

Computational investigation of molecular structures and reactions of biological and pharmaceutical interests remains a grand scientific challenge due to the size and conformational flexibility of these systems. The work requires parsing and analyzing thousands of conformations in each molecular state for meaningful chemical information and subjecting the ensemble to costly quantum chemical calculations. The current status quo typically involves a manual process where the investigator must look at each conformation, separating each into structural families. This process is time-intensive and tedious, making this process infeasible in some cases, and limiting the ability of theoreticians to study these systems. However, the …

Ensemble Data Fitting For Bathymetric Models Informed By Nominal Data, Samantha Zambo

Dissertations

Due to the difficulty and expense of collecting bathymetric data, modeling is the primary tool to produce detailed maps of the ocean floor. Current modeling practices typically utilize only one interpolator; the industry standard is splines-in-tension.

In this dissertation we introduce a new nominal-informed ensemble interpolator designed to improve modeling accuracy in regions of sparse data. The method is guided by a priori domain knowledge provided by artificially intelligent classifiers. We recast such geomorphological classifications, such as ‘seamount’ or ‘ridge’, as nominal data which we utilize as foundational shapes in an expanded ordinary least squares regression-based algorithm. To our knowledge …

Doping Of Conjugated Polymers: Preparation, Characterization And Device Fabrication, Kan Tang

Dissertations

Semiconducting conjugated polymers (CPs) as emerging materials for advanced electronic applications such as sensors, OPVs, and OEFTs has become an intriguing research topic in the past decades. It opens a new avenue of “flexible” electronics, which has shown great potential in next-generation electronic devices.

However, due to the nature of CP materials and related solution processing techniques, unlike almost perfectly crystalline silicon materials, CPs in the solid-state often exhibit much lower crystallinity if it is not complete amorphous, which severely hinder the electronic property and optical property of the materials. The crystallinity of CPs in a film is often uniquely …

Identification Of Cultural Differences And Their Effects On International Relations: A Novel Approach, Stephen W. Jones

Dissertations

International Relations suffers from underspecified treatments of culture that risk reifying, essentializing, or ignoring the effects of cultural differences in the conduct of relationships between states. Following a review of the development of the culture concept, this interpretivist, epistemologically critical realist, dissertation introduces intercultural adaptive frameshifting from the intercultural communication literature. To assess whether culture has effect within an epistemic community, four frameworks are evaluated within a non-IR field (global Christian reasoning). Speech act theory is used to assess meaningful affect through illocutionary and/or perlocutionary divergence based on cultural difference.

Following the findings that such cultural differences do in fact …

Interleukin-17a Facilitates Chikungunya Virus Infection By Inhibiting Ifn-Α2 Expression, Biswas Neupane

Dissertations

Interferons (IFNs) are the key components of innate immunity and are crucial for host defense against viral infections. Here, we report a novel role of interleukin-17A (IL-17A) in inhibiting IFN-α2 expression, thus promoting chikungunya virus (CHIKV) infection. CHIKV infected IL-17A deficient (Il17a^-/-) mice expressed a higher level of IFN-α2 and developed diminished viremia and milder footpad swelling in comparison to wild-type (WT) control mice, this was also recapitulated in IL-17A receptor-deficient (Il17ra^-/-) mice. Interestingly, IL-17A selectively blocked IFN-α2 production during CHIKV, but not West Nile virus (WNV) or Zika virus (ZIKV), infections. Recombinant IL-17A …

The Role Of The Msaabcr Operon In Cell Wall Integrity And Programmed Cell Death During Biofilm Development, Bibek G C

Dissertations

Staphylococcus aureus is an important human pathogen in both community and health care settings. Biggest challenges with S. aureus as a pathogen is its ability to acquire antibiotic resistance and produce robust biofilms. In this work, we investigated the nature of the cell wall defect in the msaABCR operon mutant in the Mu50 (VISA) and USA300 LAC methicillin-resistant Staphylococcus aureus (MRSA) strains. Results showed that msaABCR-mutant cells had decreased cell wall thickness and cell wall crosslinking in both strains. These defects are most likely due to increased murein hydrolase activity and/or nonspecific processing of murein hydrolases mediated by increased …

Gender And Cross-Cultural Invariance Of Attitudes Toward Statistics Among Non-Stem Undergraduate Students, Mihili Edirisooriya

Dissertations

Because of the wide usage of statistics in almost every field, many universities have incorporated statistics into their undergraduate and graduate curricula. Students taking statistics have often reported negative experiences and an aversion to statistics. Non-STEM students have often reported negative attitudes toward statistics (Chew & Dillon, 2014; Keeley et al., 2008). Researchers have used qualitative and quantitative approaches to measure attitudes toward statistics. The Survey of Attitudes Toward Statistics-36 (SATS-36) scale has been the most widely accepted measure to investigate attitudes toward statistics. Any psychometrically sound measurement instrument requires invariance across groups in its usage. Otherwise, measurement biases could …

An Evaluation Of The Central Coast Rangeland Coalition: Trust And Other Factors Important For Collaborative Conservation, Dustin Tran

Master of Science in Environmental Sciences and Management Projects

The proliferation of collaborative partnerships across the western United States and the lack of tools and protocols to evaluate them have been well documented. As the number and types (conservation-based, policy actions, information sharing) of collaboratives rises, there is a need for research that aims to evaluate these partnerships' performance and collaborative process considering their importance and potential to solve complex ecological, economic, and social problems. This study aims to contribute to this pool of research by interviewing the Steering Committee (SC) members of the Central Coast Rangeland Coalition (CCRC), a volunteer-based and information-sharing rangeland collaborative coalition. We evaluate and …

Multi-Material Additive Manufacturing (3d Printing), Jason Weaver

BYU Research Development Office Research Networking Conference

Multi-material Additive Manufacturing, Hybrid Manufacturing, Design for Additive Manufacturing (DfAM), 3D printing applications

Influence Of Estradiol On Bovine Trophectoderm And Uterine Gene Transcripts Around Maternal Recognition Of Pregnancy, Emmalee J. Northrop-Albrecht, Jerica J.J. Rich, Robert A. Cushman, Runan Yao, Xijin Ge, George A. Perry

Roman L. Hruska U.S. Meat Animal Research Center: Reports

Embryo survival and pregnancy success is increased among animals that exhibit estrus prior to fixed time-artificial insemination, but there are no differences in conceptus survival to d16. The objective of this study was to determine effects of preovulatory estradiol on uterine transcriptomes, select trophectoderm (TE) transcripts, and uterine luminal fluid proteins. Beef cows/heifers were synchronized, artificially inseminated (d0), and grouped into either high (highE2) or low (lowE2) preovulatory estradiol. Uteri were flushed (d16); conceptuses and endometrial biopsies (n = 29) were collected. RNA sequencing was performed on endometrium. Real-time polymerase chain reaction (RT-PCR) was performed on TE (n = 21) …

Multi-Scale And Collaborative Disaster Evacuation Planning Framework, Dahai Liu, Kai Zhang, Yongxin Liu, Yupeng Yang, Houbing Song

Center for Advanced Transportation Mobility

When emergency occurs, no tools are available to assist the decision‐making of airline planning and coordination. In this project, we use big data and multi‐agent modeling to integrate ADS‐B data and weather information, to optimize and visualize the airspace strategic planning during disaster, and develop a forecast and recommendation system to aid the authorities and public for optimal airline evacuation process, by using the deep reinforcement learning technique.

Proceedings Of The Harmful Algal Bloom (Hab) Preparedness & Response Virtual Workshop And Tabletop Exercise, Coastal Response Research Center

Coastal Response Research Center

On April 27 - 28, 2021, CRRC and DPP co-sponsored a virtual workshop entitled “Harmful Algal Bloom (HAB) Preparedness & Response.” The workshop focused on HAB preparedness and response capabilities and responsibilities across the Federal Interagency Working Group on Harmful Algal Bloom and Hypoxia Research and Control Act (IWG – HABHRCA) members and select state agencies. Workshop participants represented academia, Federal, state, and local agencies. The two-day workshop included plenary presentations from Federal, state, and non-government agency representatives outlining: their roles and responsibilities; risk and crisis communication strategies; tools for early detection, measurement quantification, and mitigation; and public health and …

Why Targeted Testing Matters: Evaluation Of A Practice Change In Pediatric Ingestion Screening., Emily Neal

Doctor of Nursing Practice Papers

Background: The drug epidemic is plaguing the United States and more Americans than ever have been identified to use illicit substances regularly, including while caring for children. The practice of obtaining a standard urine or serum drug screen is outdated and ineffective in determining if children have been exposed to illicit substances. Often these immunoassay drug screens are negative despite pediatric patients having symptomatic responses to illicit drug exposures. Immunoassay drug screens are not designed for testing in children who are often passively and directly exposed as bystanders to adult drug use in their environment. This means that a “negative” …

Student Success And Experience Task Force Report - Etsu 125 - Chapter Ii, Student Success And Experience Task Force, East Tennessee State University

ETSU 125 - Chapter II

Chair: Dr. Chris Keller, Dean Honors College

Staff Lead: Dr. Leah Adinolfi, Associate Dean of Students

Members: Wesley Wehde, Susan Epps, Stephen Hendrix, Patrick Brown, Cerrone Foster, Alison Barton, Shivam Patel, Nicholas Jordan, Stefanie Murphy, Joy Fulkerson, Brian Thompson, Sam Hensley, and John King.

Purpose:

Bring together the diverse perspectives of the ETSU community to develop a focused vision of a destination campus for students, a campus where students from all backgrounds can succeed.

Explore opportunities to make continued progress towards the objectives of the Complete College Tennessee Act, revising institutional objectives as appropriate.

Research And Scholarship Task Force Report - Etsu 125 - Chapter Ii, Research And Scholarship Task Force, East Tennessee State University, Committee For 125, East Tennessee State University

ETSU 125 - Chapter II

Chair: Dr. Joe Bidwell, Interim-Dean College of Arts and Sciences

Staff Lead: Dr. Nick Hagemeier, Presidential Fellow

Members: Jonathan Peterson, Eric Sellers, Ron Roach, Stephen Marshall, Pam Mims, Blaine Shubert, Josie Ward, Ashley McBee, Robert Pack, Greg Ordway, Scott Andrew, Nick Hagemeier, Daniel Westover, William Hopkins, and Elwood Watson.

Purpose:

Conduct a comprehensive review of the ETSU research and scholarship environment and develop a vision for the future that grows faculty and student participation in research and scholarship as well as increase funding derived from those activities.

Explore opportunities to advance our research infrastructure, creating business and industry partnerships as …

Etsu Health Task Force Report - Etsu 125 - Chapter Ii, Etsu Health Task Force, East Tennessee State University

ETSU 125 - Chapter II

Chair: Dr. David Linville, Executive Vice Provost for Academics and Health

Staff Lead: Dr. Megan Quinn, Presidential Fellow

Members: Skylar Moore, Melissa Nipper, Claire Roberson, Kennedy Aerhart, Kimberly Hale, Nakia Woodward, Judith Rice, Kara Gilliam, Fernando Calogero, Randy Wykoff, and Wally Dixon.

Purpose:

Explore opportunities for ETSU Health to maximize the academic, clinical, and research mission of the institution while ensuring strong linkages to the other academic units across the campus and identify current and potential external partners.

Promote the growth and development of ETSU Health so that it emerges as the practice of choice for our region.

Men's Soccer Media Guide 2021, Wofford College. Department Of Athletics

Media Guides

No abstract provided.

Football Media Guide 2021, Wofford College. Department Of Athletics

Media Guides

No abstract provided.

Women's Soccer Media Guide 2021, Wofford College. Department Of Athletics

Media Guides

No abstract provided.

Volleyball Media Guide 2021, Wofford College. Department Of Athletics

Media Guides

No abstract provided.

Oer Workshops For Learning (Owls), Maria T. Torres

Education

Learning resources for an engaging workshop on OER basics using gamification.

2021 Fall - Schedule Of Classes, Office Of The Registrar, East Tennessee State University

Registration Resources

No abstract provided.

Kentucky Warbler (Vol. 97, No. 3), Kentucky Library Research Collections

The Kentucky Warbler

No abstract provided.

People With Disabilities Still At Risk In Congregate Care Settings, University Of Montana Rural Institute

Health and Wellness

This report provides an analysis of data to better understand where cases and deaths are rising in nursing homes as of August 8 2021. We hope this analysis can help support local community planning and networking among rural partners to improve outcomes.

• COVID-19 cases among residents and staff are on the rise in nursing homes with the steepest increases in urban areas and in the South and Midwest.
• Disabled people are disproportionately overrepresented in the resident populations of unsafe congregate settings, such as nursing homes.
• Vaccination rates across both residents and staff in nursing homes have stagnated.
• Policy priorities should …

Statistics Education From The Perspective Of Statistical Literacy: Reflections Taken From Studies With Teachers, Carlos Eduardo Ferreira Monteiro, Liliane Maria Teixeira Lima De Carvalho

The Mathematics Enthusiast

The aim of this article is to discuss aspects of statistical literacy from research on statistics education conducted with teachers and developed by the Research Group on Mathematics and Statistics Education (GPEME) at the Universidade Federal de Pernambuco (UFPE). These investigations were influenced by international discussions on a perspective of statistical literacy that focuses not only on knowledge and technical procedures of curriculum content in statistics, but also on developing critical attitudes towards approaching data. The reflections are based on the analysis of research with teachers of different levels and teaching modalities, who engaged in problem-solving activities associated with various …