Digital Commons Network^™

Anti-Tumoral Activity Of Acetogenins Derived From Soursop Fruit (Annona Muricata L.) In High Grade Serous Ovarian Cancer, Roger Neuberger, Paola Amero, Cristian Rodriguez-Aguayo, Efigenia Montalvo-González, Gabriel Lopez-Berestein

Summer Experience 2021

No abstract provided.

My Mother She Killed Me, My Father He Ate Me., John Rosegrant

Mythcon

In this presentation I explore why Tolkien singled out for particular appreciation the Brothers Grimm fairy tale The Juniper Tree, which Tatar (Annotated Grimm 209) has called “the most shocking of all fairy tales.” In On Fairy-Stories, Tolkien described its effect on him as follows: “The beauty and horror of The Juniper Tree…with its exquisite and tragic beginning, the abominable cannibal stew, the gruesome bones, the gay and vengeful bird-spirit coming out of a mist that rose from the tree, has remained with me since childhood; and yet always the chief flavor of that tale lingering in …

Why Farmers Don't Always Practice 'Optimum' Management: Case Study Of Small Stock Ranching Systems In Southern Namibia, Stephanie E. Domptail, Alexander Popp, Ernst‐August Nuppenau

IGC Proceedings (1977-2023)

No abstract provided.

Assessing The Contribution Of Mixed Farming Systems To Biodiversity Across Australia's Sheep‐Wheat Zone: The Grain & Graze Participatory Research Model, Kerry L. Bridle, Peter Mcquillan, Dave Green, Janet Smith, Margy Fitzgerald, Ted Lefroy

IGC Proceedings (1977-2023)

No abstract provided.

Pilot-Scale H2S And Swine Odor Removal System Using Commercially Available Biochar, Kyoung S. Ro, Brian Woodbury, Mindy Spiehs, Ariel A. Szogi, Philip J. Silva, Okhwa Hwang, Sungback Cho

Roman L. Hruska U.S. Meat Animal Research Center: Reports

Although biochars made in laboratory seem to remove H2S and odorous compounds effectively, very few studies are available for commercial biochars. This study evaluated the efficacy of a commercial biochar (CBC) for removing H2S and odorous volatile organic compounds (VOCs). We found that the well-known Ergun equation may not be adequate in predicting pressure drop for properly sizing a ventilation system. The H2S breakthrough adsorption capacity of the CBC was 2.51 mg/g under humid conditions, which was much higher than that for dry conditions. The breakthrough capacity increased with the influent concentration of H2S. The efficacy of a pilot-scale biochar …

The Ovarian Follicle Of Ruminants: The Path From Conceptus To Adult, Jennifer L. Juengel, Robert A. Cushman, Joëlle Dupont, Stéphane Fabre, Richard G. Lea, Graeme B. Martin, Francesca Mossa, Janet L. Pitman, Christopher A. Price, Peter Smith

Roman L. Hruska U.S. Meat Animal Research Center: Reports

This review resulted from an international workshop and presents a consensus view of critical advances over the past decade in our understanding of follicle function in ruminants. The major concepts covered include: (1) the value of major genes; (2) the dynamics of fetal ovarian development and its sensitivity to nutritional and environmental influences; (3) the concept of an ovarian follicle reserve, aligned with the rise of anti-Müllerian hormone as a controller of ovarian processes; (4) renewed recognition of the diverse and important roles of theca cells; (5) the importance of follicular fluid as a microenvironment that determines oocyte quality; (6) …

Evolution Of The Sheep Industry And Genetic Research In The United States: Opportunities For Convergence In The Twenty-First Century, J. W. Thorne, B. M. Murdoch, B. A. Freking, R. R. Redden, Thomas W. Murphy, J. B. Taylor, Harvey D. Blackburn

Roman L. Hruska U.S. Meat Animal Research Center: Reports

The continuous development and application of technology for genetic improvement is a key element for advancing sheep production in the United States. The US sheep industry has contracted over time but appears to be at a juncture where a greater utilization of technology can facilitate industry expansion to new markets and address inefficiencies in traditional production practices. Significant transformations include the increased value of lamb in relation to wool, and a downtrend in large-scale operations but a simultaneous rise in small flocks. Additionally, popularity of hair breeds not requiring shearing has surged, particularly in semi-arid and subtropical US environments. A …

The Role Of Dnd1 In Cancers, Yun Zhang, Jyotsna D. Godavarthi, Abie Williams-Villalobo, Shahrazad Polk, Angabin Matin

Faculty Publications

The Ter mutation in Dead-End 1 (Dnd1), Dnd1Ter, which leads to a premature stop codon, has been determined to be the cause for primordial germ cell deficiency, accompanied with a high incidence of congenital testicular germ cell tumors (TGCTs) or teratomas in the 129/Sv-Ter mice. As an RNA-binding protein, DND1 can bind the 3′-untranslated region (3′-UTR) of mRNAs and function in translational regulation. DND1 can block microRNA (miRNA) access to the 3′-UTR of target mRNAs, thus inhibiting miRNA-mediated mRNA degradation and up-regulating translation or can also function to degrade or repress mRNAs. Other mechanisms of DND1 activity include promoting translation …

Probiotics In Prevention And Treatment Of Covid-19: Current Perspective And Future Prospects, Shilia Jacob Kurian, Mazhuvancherry Kesavan Unnikrishnan, Sonal Sekhar Miraj, Debasis Bagchi, Mithu Banerjee, B. Shrikar Reddy, Gabriel Sunil Rodrigues, Mohan K. Manu, Kavitha Saravu, Chiranjay Mukhopadhyay, Mahadev Rao

Faculty Publications

Saving lives and flattening the curve are the foremost priorities during the ongoing pandemic spread of SARS-CoV-2. Developing cutting-edge technology and collating available evidence would support frontline health teams. Nutritional adequacy improves general health and immunity to prevent and assuage infections. This review aims to outline the potential role of probiotics in fighting the COVID-19 by covering recent evidence on the association between microbiota, probiotics, and COVID-19, the role of probiotics as an immune-modulator and antiviral agent. The high basic reproduction number (R0) of SARS-CoV-2, absence of conclusive remedies, and the pleiotropic effect of probiotics in fighting influenza and other …

Litigating For Legality: Nature Conservation, Commercial Fisheries And Disputed Territoriality In Ukraine’S Danube Delta, Tanya Richardson

Anthropology Faculty Publications

Between 2014 and 2016 Ukraine’s Danube Biosphere Reserve (DBR) administrators devoted extensive time to lawsuits in which they defended the legality of commercial fisheries in reserve territory. Two cases are discussed in order to examine what impact litigation had and why administrators pursued litigation when dominant accounts of law in Ukraine suggest that avoiding the courts might be a more likely response. It analyzes court documents and interviews gathered during anthropological research about nature conservation in the Danube Delta by combining insights from political ecology, agrarian studies, and socio-legal scholarship on Ukraine. Even though administrators lost their cases and had …

Sleep Disparities During The Covid-19 Pandemic An Investigation Of Aian, Asian, Black, Latinx And White Young Adults, Tiffany Yip, Ye Feng, Jillianne Fowle, Celia B. Fisher

Covid-19 Digital Research

Objectives: This study investigates race-related disparities in sleep duration and quality among diverse young adults during the coronavirus 2019 (COVID-19) pandemic.

Design & setting: Online cross-sectional study of young adults in the United States in April 2020.Participants:About 547 American Indian/Alaskan Native (AIAN), Asian, Black, Latinx, and White young adults ages 18-25 years.

Measurements: Participants completed measures of sleep duration and quality, coronavirus victimization dis-tress, depression, age, sex/gender, employment status, essential worker status, student status, residential region, socioeconomic status, concerns about contracting coronavirus and CDC health risks.

Results: Black young adults reported the largest disparity in sleep duration and quality. For …

The Role Of Yantak “Alhagi” Species In The Biological Diversity Of The Deserts Of Uzbekistan, Khudargan Mavlonov, Surayyo Kodirova

Mental Enlightenment Scientific-Methodological Journal

This article provides information on the occurrence, importance, role of Alhagi species in biodiversity (phytocenosis), eco-biological features, allelopathy.

A Study Of Information Literacy Instruction And Its Impact On Stem Students At Hbcus, Dawn Ventress Kight

Electronic Dissertations and Theses

In today’s complex information environment, students are entering college underprepared and lacking Information Literacy (IL) skills as they matriculate in STEM disciplines. Some universities have not developed effective systematic approaches for IL instructional programs to aid students in developing necessary 21st century IL skills. Therefore, the purpose of this study was to investigate Information Literacy (IL) instruction and the impact it has on student achievement for students majoring in Science, Technology, Engineering, and Math (STEM) disciplines. This qualitative research followed a transcendental phenomenological approach by documenting and giving voice to the lived experiences of participants at HBCUs in a Southern …

Winner-Loser Effects Part 3, Omar T. Eldakar, Natalie Buckwold, Andrew C. Gallup

Biology Faculty Datasets

The dataset is part of an investigation of patterns of wins and losses of two-, three-, and four-game collegiate baseball series for analysis of winner and loser, and residency effects. The dataset is a compilation of publicly available data from Atlantic 10, Conference USA, and Sunbelt conferences for the years 2015-2019.

Yield And Economic Performance Of Crop Rotation Systems In South Dakota, Hanxiao Feng, Tong Wang, Shannon L. Osborne, Sandeep Kumar

Economics Faculty Publications

Crop yield and economic profitability, both highly dependent on local crop management, soil characteristics, and weather conditions, are among the most influential factors to consider when considering a cropping system. The objective of this study was to compare the economic returns of three different 4-yr diverse crop rotations with that of a 2-yr traditional crop rotation in eastern South Dakota. The rotations included were (a) corn (Zea mays L.)–soybean [Glycine max (L.) Merr.]–spring wheat (Triticum aestivum L.)–pea (Pisum sativum L.) (CSSwP), (b) corn–pea–winter wheat–soybean (CPWwS), (c) corn–oat (Avena sativa L.)–winter wheat–soybean (COWwS), and (d) corn–soybean …

Refining The Coarse Filter Approach: Using Habitat-Based Species Models To Identify Rarity And Vulnerabilities In The Protection Of U.S. Biodiversity, Anne Davidson, Leah Dunn, Kevin Gergely, Alexa Mckerrow, Steven Williams, Mackenzie Case

University Author Recognition Bibliography: 2021

Preserving biodiversity and its many components is a priority of conservation science and how to efficiently allocate resources to preserve healthy populations of as many species, habitats, and ecosystems as possible. We used the U.S. Geological Survey (USGS) Gap Analysis Project (GAP) species models released in 2018, which identify predicted habitats for terrestrial vertebrates in the conterminous United States, to illustrate hotspots of biodiversity for the major taxonomic groups. This collection represents the first complete compilation of terrestrial vertebrate species models for the conterminous United States (U.S. Geological Survey (USGS), 2018a). We used the species models but not the available …

Fear Then And Now: The Vampire As A Reflection Of Society, Mackenzie Phelps

English (MA) Theses

Over the expanse of centuries, human society has created monsters in order to give a physical form to their abstract fears. Society has gone from speaking of them in oral traditions to watching them on a screen in more recent decades, but the written works of these monstrosities have occurred in the multitudes across multiple eras. The globalized monster I have chosen to focus on here is the vampire. Said vampires are witnessed as changing over time to adjust to the awakening or loss of certain human fears, distresses, and perceived threats—whether that be war, religion, race, etc. While …

The Greenbook, Faculty Handbook, 2021-2022, Marshall University Academic Affairs

The Greenbook

This book has been published for the faculty of Marshall University for the specified period of time. This book was created by Academic Affairs and is for the period of 2021-2022.

The Degree Of Polymerization And Sulfation Patterns In Heparan Sulfate Are Critical Determinants Of Cytomegalovirus Entry Into Host Cells, Dipanwita Mitra, Mohammad H. Hasan, John T. Bates, Michael A. Bierdeman

Faculty and Student Publications

Several enveloped viruses, including herpesviruses attach to host cells by initially interacting with cell surface heparan sulfate (HS) proteoglycans followed by specific coreceptor engagement which culminates in virus-host membrane fusion and virus entry. Interfering with HS-herpesvirus interactions has long been known to result in significant reduction in virus infectivity indicating that HS play important roles in initiating virus entry. In this study, we provide a series of evidence to prove that specific sulfations as well as the degree of polymerization (dp) of HS govern human cytomegalovirus (CMV) binding and infection. First, purified CMV extracellular virions preferentially bind to sulfated longer …

(E)-2,6,10-Trimethyldodec-8-En-2-Ol: An Undescribed Sesquiterpenoid From Copaiba Oil, Mohammed F. Hawwal, Zulfiqar Ali, Mei Wang, Jianping Zhao

Faculty and Student Publications

The use of copaiba oil has been reported since the 16th century in Amazon traditional medicine, especially as an anti-inflammatory ingredient and for wound healing. The use of copaiba oil continues today, and it is sold in various parts of the world, including the United States. Copaiba oil contains mainly sesquiterpenes, bioactive compounds that are popular for their positive effect on human health. As part of our ongoing research endeavors to identify the chemical constituents of broadly consumed herbal supplements or their adulterants, copaiba oil was investigated. In this regard, copaiba oil was subjected to repeated silica gel column chromatography …

Red Algal Sulfated Galactan Binds And Protects Neural Cells From Hiv-1 Gp120 And Tat, Vitor H. Pomin, Fakhri Mahdi, Weihua Jin, Fuming Zhang

Faculty and Student Publications

The potential neuroprotective capacity of four different sulfated glycans: Botryocladia occidentalis-derived sulfated galactan (BoSG) (MW > 100 kDa), Lytechinus variegatus-derived sulfated fucan (LvSF) (MW~90 kDa), high-molecular weight dextran sulfate (DxS) (MW 100 kDa), and unfractionated heparin (UFH) (MW~15 kDa), was assessed in response to the HIV-1 proteins, R5-tropic glycoprotein 120 (gp120) and/or trans-activator of transcription (Tat), using primary murine neurons co-cultured with mixed glia. Compared to control-treated cells in which HIV-1 proteins alone or combined were neurotoxic, BoSG was, among the four tested sulfated glycans, the only one capable of showing significant concentration-dependent neuroprotection against Tat and/or gp120, alone or combined. …

History Of Mathematics Education In Brazil: An Overview Of Secondary Education, Maria Laura Magalhães Gomes, Antonio Vicente Marafioti Garnica

The Mathematics Enthusiast

The field of the history of mathematics education, inscribed in the field of research on mathematics education in Brazil, has been developed as a result of the work of many groups of researchers, dedicated to varied themes under the light of various theoretical and methodological approaches. While it is impossible to describe in detail such studies in a single article, the objective of this text is to offer an overview of research results on a specific topic – mathematics in secondary education and training of teachers to teach at this level, over the years.

The current situation of the country …

Enhancing Microbiome Host Disease Prediction With Variational Autoencoders, Celeste Manughian-Peter

Computational and Data Sciences (MS) Theses

Advancements in genetic sequencing methods for microbiomes in recent decades have permitted the collection of taxonomic and functional profiles of microbial communities, accelerating the discovery of the functional aspects of the microbiome and generating an increased interest among clinicians in applying these techniques with patients. This advancement has coincided with software and hardware improvements in the field of machine learning and deep learning. Combined, these advancements implicate further potential for progress in disease diagnosis and treatment in humans. The ability to classify a human microbiome profile into a disease category, and additionally identify the differentiating factors within the profile between …

Uncertainty Quantification, Douglas Cook

BYU Research Development Office Research Networking Conference

What are the limitations of scientific models? Uncertainty quantification, Sensitivity analyses, Theory-based and statistical modeling, Systems thinking, systems analysis

Carbon Nanodots Inhibit Oxidized Low Density Lipoprotein-Induced Injury And Monocyte Adhesion To Endothelial Cells Through Scavenging Reactive Oxygen Species, Safeera Khan, Jessica Chavez, Xuewei Zhu, Norman H. Chiu, Wendi Zhang, Ziyu Yin, Jian Han, Jibin Yang, Robert Sigler, Shaomin Tian, Hong Zhu, Y R. Li, Jianjun Wei, Xianwen Yi, Zhenquan Jia

Osteopathic Medicine, Jerry M. Wallace School of

Oxidized low density lipoprotein (Ox-LDL) is a known biomarker of inflammation and atherosclerosis, a leading cause of death worldwide. As a new class of nanomaterials, carbon nanodots (CNDs) are widely used in bioimaging, diagnostics, and drug delivery. However, there is no current report on how these CNDs affect the cardiovascular system, particularly their potential in mediating endothelial inflammatory dysfunction. This study examined effects of CNDs on Ox-LDL-mediated endothelial dysfunction. CNDs significantly inhibited Ox-LDL-mediated adhesion of monocytes to human microvascular endothelial cells (HMEC-1), in human microvascular endothelial cells (HMEC-1). CNDs significantly inhibited Ox-LDL-mediated adhesion of monocytes to endothelial cells, which is …

Facile Atomic-Level Structure Determination Of Proteins, James Moody

BYU Research Development Office Research Networking Conference

Protein structure and function, Protein crystallization methods, Enzymology, Enzyme engineering

Using X-Ray Vision To Understand How Things Break: Lensless X-Ray Imaging Of Materials In Extreme Conditions, Richard Sandberg

BYU Research Development Office Research Networking Conference

Microscopy, nanotechnology, optics, inverse problems, applied math, materials science, computer science, data science, x-ray imaging and diffraction

Polydnavirus Innexins Disrupt Host Cellular Encapsulation And Larval Maturation, Peng Zhang, Matthew Turnbull

Open Access Publishing Fund

Polydnaviruses are dsDNA viruses associated with endoparasitoid wasps. Delivery of the virus during parasitization of a caterpillar and subsequent virus gene expression is required for production of an amenable environment for parasitoid offspring development. Consequently, understanding of Polydnavirus gene function provides insight into mechanisms of host susceptibility and parasitoid wasp host range. Polydnavirus genes predominantly are arranged in multimember gene families, one of which is the vinnexins, which are virus homologues of insect gap junction genes, the innexins. Previous studies of Campoletis sonorensis Ichnovirus Vinnexins using various heterologous systems have suggested the four encoded members may provide different functionality in …

Sulfur Isotopes As A Proxy For Human Diet And Mobility From The Preclassic Through Colonial Periods In The Eastern Maya Lowlands, Claire E. Ebert, Asta J. Rand, Kirsten Green-Mink, Julie A. Hoggarth, Carolyn Freiwald, Jaime J. Awe, Willa R. Trask, Jason Yaeger, M. Kathryn Brown, Christophe Helmke, Rafael A. Guerra, Marie Danforth, Douglas J. Kennett

Faculty and Student Publications

Maya archaeologists have long been interested in understanding ancient diets because they provide information about broad-scale economic and societal transformations. Though paleodietary studies have primarily relied on stable carbon (δ13C) and nitrogen (δ15N) isotopic analyses of human bone collagen to document the types of food people consumed, stable sulfur (δ34S) isotope analysis can potentially provide valuable data to identify terrestrial, freshwater, or marine/coastal food sources, as well as determine human mobility and migration patterns. Here we assess applications of δ34S for investigating Maya diet and migration through stable isotope analyses of human bone collagen (δ13C, δ15N, and δ34S) from 114 …

Bacterial High Throughput Platform For Drug Discover, Dario Mizrachi

BYU Research Development Office Research Networking Conference

Synthetic biology, Tight Junctions, Membrane proteins