Digital Commons Network^™

A Rapid Screening Method For Ecological Risks Posed By Different Land Use Intensities: Case Study Of Marikina City’S River System, Maria Aileen Leah Guzman, Charlotte Kendra Gotangco Gonzales, Rene Juna Claveria, Philippe Joshua Evardo, Jean Jardeleza Mijares

Journal of Management for Global Sustainability

Land use plays an important role in environmental and sustainability research because of its potential contribution to ecosystem protection or degradation. However, most risk maps used in comprehensive land use planning only identify areas at risk, for example, to various geophysical or climate- and weather-related hazards. It would also be useful to identify land areas that pose a risk to ecological systems. In this study, a simplified method adapted from the source-habitat approach and the relative risk model was used to explore the potential ecological risk of exposure to water pollutants posed by land uses on the river system in …

Genetic Diversity Of Huaya India (Melicoccus Oliviformis Kunth), A Neglected Neotropical Fruit Crop, Mónica I. Jiménez-Rojas, Rubén H. Andueza-Noh, Obed I. Noh-Ake, Daniel Potter, Matilde M. Ortiz-García, Renee S. Arias, Jaime Martínez-Castillo

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Currently, some species of Sapindaceae are important fruit crops worldwide. The Huaya India (Meliccocus oliviformis, Sapindaceae) is a neglected Neotropical fruit tree consumed locally in the Maya Lowlands of Mexico, where it exists in both wild and domesticated forms. Our objective was to evaluate the genetic diversity of the Huaya India in its possible domestication area and thus generate knowledge that serves as the basis for a commercial management. A total of 450 individuals collected from 15 natural vegetation sites and 15 Maya villages, were characterized using nine microsatellite loci and population genetics approaches were applied. STRUCTURE, Neighbor-Joining and PCoA …

Development And Application Of A Novel Acoustic Microfluidic Technology For Single Cell Per Well Trapping And High-Resolution Analysis Of Cilia Motion In Chlamydomonas Reinhardtii, Mingyang Cui

McKelvey School of Engineering Graduate Student Theses & Dissertations

Acoustic manipulation of cells and microorganisms is a label-free and contact-free technique with promise for biological and biomedical applications. When exposed to an ultrasonic standing wave field, particles suspended in microfluidic channels will be moved to pressure minima (nodes) or maxima (antinodes) due to the acoustic impedance mismatch between particles and the suspension medium. Cilia motion is fundamental to understanding biological and biomedical problems related to dysfunctional human cilia, including primary ciliary dyskinesia, blindness, and male infertility. However, in vivo and ex vivo mammalian ciliated cell research is laborious and time-consuming due to difficulty in growing, maintaining, and imaging these …

Photoacoustic Imaging Of Colorectal Cancer And Ovarian Cancer, Xiandong Leng

McKelvey School of Engineering Graduate Student Theses & Dissertations

Photoacoustic (PA) imaging is an emerging hybrid imaging technology that uses a short-pulsed laser to excite tissue. The resulting photoacoustic waves are used to image the optical absorption distribution of the tissue, which is directly related to micro-vessel networks and thus to tumor angiogenesis, a key process in tumor growth and metastasis. In this thesis, the acoustic-resolution photoacoustic microscopy (AR-PAM) was first investigated on its role in human colorectal tissue imaging, and the optical-resolution photoacoustic microscopy (OR-PAM) was investigated on its role in human ovarian tissue imaging.Colorectal cancer is the second leading cause of cancer death in the United States. …

Acoustic Radiation Force And Its Application For Cell Manipulation And Ion Channels Activation, Xiangjun Peng

McKelvey School of Engineering Graduate Student Theses & Dissertations

Sound is a stress wave that carries energy and momentum flux. Scattered sound waves can generate acoustic radiation force that can be used to manipulate particles or cells. This dissertation demonstrates the physics behind cell manipulation by ultrasound. The work begins with a detailed analysis of the mechanics of using standing surface acoustic waves to fabricate acoustic tweezers for contactless particle manipulation using acoustic radiation force. Models to design and analyze acoustic radiation force have traditionally relied on plane wave theories that cannot predict how standing surface acoustic waves can levitate cells in the direction perpendicular to the substrate. We …

Anion Exchange Membranes In Electrochemical Energy Systems, Yunzhu Zhang

McKelvey School of Engineering Graduate Student Theses & Dissertations

Non-CO2-emitting sources of renewable energy, such as solar and wind, have become quite popular in recent years, and their electricity generation cost at scale has become comparable with that of gas- and coal-fired power plants. However, their intermittent output makes the resultant electricity hard to dispatch in a reliable manner in the absence of grid-scale electrical energy storage (EES) technologies. Redox-flow batteries (RFBs) are promising devices for medium- to large-scale electric energy storage. They are safe, reliable, and portable, and are designed with decoupled power and energy modules, which makes it easy and cost-effective to scale their output to meet …

Effect Of A Rehabilitation Program On Quality Of Life Among 2nd Degree Burn Adolescents Quasi Experimental Study, Sara Sayed Abdalla

Nursing

No abstract provided.

Deep Convolutional Neural Networks For Accurate Diagnosis Of Covid-19 Patients Using Chest X-Ray Image Databases From Italy, Canada, And The Usa, Amgad A. Salama, Samy H. Darwish, Samir M. Abdel-Mageed, Radwa A. Meshref, Ehab I. Mohamed

The University of Louisville Journal of Respiratory Infections

Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), famously known as COVID-19, has quickly become a global pandemic. Chest X-ray (CXR) imaging has proven reliable, fast, and cost-effective for identifying COVID-19 infections, which proceeds to display atypical unilateral patchy infiltration in the lungs like typical pneumonia. We employed the deep convolutional neural network (DCNN) ResNet-34 to detect and classify CXR images from patients with COVID-19 and Viral Pneumonia and Normal Controls.

Methods: We created a single database containing 781 source CXR images from four different international sub-databases: the Società Italiana di Radiologia Medica e Interventistica (SIRM), the GitHub Database, the …

Detecting Apple Crop Pest Insects From Eptesicus Fuscus (Big Brown Bat) Feces Using Metabarcoding In Southern Michigan Apple Orchards, Randi Lesagonicz

Masters Projects

Michigan is ranked third in the U.S. for apple production. Michigan State University identified 78 pest insect species that cause damage to Michigan’s crop. Orchards using conventional and integrated pest management (IPM) spend thousands of dollars on pest control substances, which are hazardous to the environment and human health, and do not prevent 100% of crop damage and losses. The public’s increasing desire for “cleaner” foods has led to studies on how to incorporate more naturally occurring pest biocontrol agents. Bats have been recognized as pest insect biocontrol agents in numerous U.S. agroecosystems like corn, cotton, and pecans; however, little …

Depression As A Moderator Of The Relationship Between Perceived Injustice And Neuropsychological Performance Validity Among Individuals Previously Diagnosed With A Concussion, Jeremiah Lum

Clinical Psychology Dissertations

Concussion is one of the most common conditions seen within rehabilitation and neuropsychology. Given that many concussions are diagnosed following litigation-associated injuries, it is unsurprising that malingered neurocognitive deficit (i.e., deliberate underperformance on cognitive instruments in the interest of secondary gain) has dominated the concussion literature. Although the identification of malingering is essential to ethical assessment, its presence or absence is not the sole determinant of performance validity as a whole. Rather, performance validity is a broad construct involving effort, which refers to examinees’ investment in performing at capacity levels; emerging research suggests this can be affected by psychological factors …

Cold Conditioned: Discovery Of Novel Alleles For Low-Temperature Tolerance In The Vavilov Barley Collection, Ahmad H. Sallam, Kevin P. Smith, Gongshe Hu, Jamie Sherman, Peter Stephen Baeziger, Jochum Wiersma, Carl Duley, Eric J. Stockinger, Mark E. Sorrells, Tamas Szinyei, Igor G. Loskutov, Olga N. Kovaleva, Jed Eberly, Brian J. Steffenson

Department of Agronomy and Horticulture: Faculty Publications

Climate changes leading to higher summer temperatures can adversely affect cool season crops like spring barley. In the Upper Midwest region of the United States, one option for escaping this stress factor is to plant winter or facultative type cultivars in the autumn and then harvest in early summer before the onset of high-temperature stress. However, the major challenge in breeding such cultivars is incorporating sufficient winter hardiness to survive the extremely low temperatures that commonly occur in this production region. To broaden the genetic base for winter hardiness in the University of Minnesota breeding program, 2,214 accessions from the …

Low-Level Groundwater Atrazine In High Atrazine Usage Nebraska Counties: Likely Effects Of Excessive Groundwater Abstraction, Moses New-Aaron, Olufemi P. Abimbola, Raheleh Mohammadi, Oluwaseun Famojuro, Zaeema Naveed, Azar M Abadi, Jesse E. Bell, Shannon Bartelt-Hunt, Eleanor G. Rogan

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Recent studies observed a correlation between estrogen-related cancers and groundwater atrazine in eastern Nebraska counties. However, the mechanisms of human exposure to atrazine are unclear because low groundwater atrazine concentration was observed in counties with high cancer incidence despite having the highest atrazine usage. We studied groundwater atrazine fate in high atrazine usage Nebraska counties. Data were collected from Quality Assessed Agrichemical Contaminant Nebraska Groundwater, Parameter–Elevation Regressions on Independent Slopes Model (PRISM), and water use databases. Descriptive statistics and cluster analysis were performed. Domestic wells (59%) were the predominant well type. Groundwater atrazine was affected by well depth. Clusters consisting …

On The Bookshelf, Susan Dumais

UNH Today Archive

No abstract provided.

Virology: Mutagenizing The Proteolytic Cleavage Site In The Major Capsid Protein In Ssv1, Thejanee Liyanaarachchi

University Honors Theses

SSV1, spindle-shaped virus 1, is an archaeal virus with a unique shape that belongs to the family of fuselloviruses and infects hyperthermophilic archaea that thrive at 80°C and pH 3. SSV1 has two capsid proteins, VP1 and VP3, that presumably produce the lemon-shaped virion structure characteristic of fuselloviruses. The VP1 amino acid sequence is highly conserved among SSVs. Here, we investigate the importance of the proteolytic cleavage site in position E66 in VP1 by changing its glutamic acid to the other 19 amino acids. We have developed a new protocol for creating SSV1 mutants through HiFi Assembly (NEB) to increase …

An Investigation Into The Relationship Between Obstetric Racism And Postpartum Depression In Black Women, Miguel A. Claxton Iii

University Honors Theses

Postpartum depression is the most common postpartum mood disorder, with 13% of new mothers reporting symptoms within the first year. Adverse birth outcomes, such as low birth weight and preterm birth co-index with the development of postpartum depression. This correlation is particularly alarming considering that Black women have about a 60% higher rate of preterm birth and an 88% higher rate of low birth weight infants than Caucasian women. By utilizing theories of stratified reproduction, necropolitics, and obstetric racism, this paper aims to situate postpartum depression in Black women as a psychological response to systems of medicolegal control and domination. …

End Matter, Vol. 81 No. 4

Western North American Naturalist

No abstract provided.

Nesting Biology And Offspring Development Of The Cavity-Nesting Solitary Wasp Isodontia Elegans (F. Smith) From Trap-Nests In Oregon, Ronald C. Spendal, Kevin M. O'Neill, Casey M. Delphia

Western North American Naturalist

We studied the nesting biology and developmental schedules of the cavity-nesting solitary wasp Isodontia elegans in Oregon, USA. Trap-nests contained 1–15 brood cells each, separated by partitions, which adult females made with grass fragments. Before leaving nests to hunt, females made loose, temporary closures of longer fragments of dried grass and, upon returning, briefly deposited prey just inside the nest entrance before transferring them to a cell. Cells were provisioned with katydids (Meconema thalassinum, an invasive species in North America) and tree crickets (Oecanthus fultoni), the latter predominating as summers progressed. The inner cells of nests, …

Front Matter, Vol. 81 No. 4

Western North American Naturalist

No abstract provided.

Characterization Of Bacteriophage Targeting Bacillus Licheniformis In Milk Processes And Thermal Stability Of Bacteriophage During Htst Pasteurization, Jeremy Robert Arbon

Theses and Dissertations

An array of Bacillus licheniformis strains were isolated from a commercial powdered milk process. Bacteriophages exhibiting activity against B. licheniformis were isolated from cattle manure and effluent samples destined for a lagoon at a dairy farm. After sequencing, 8 of the 10 phages were found to be novel and genetically differentiated. Transmission electron scanning microscopy (TSEM) was performed. All bacteriophages were of the family Herelleviridae with contractile tail sheaths ranging from 80µm to 150µm and, surprisingly, survived a common fluid milk processing treatment used to inactivate vegetative cells. The survival of the phage after high temperature short time pasteurization of …

Regional Reprogramming And The Small Intestine: Analysis And Modeling Of Adaptive Regeneration Of The Epithelium, Sarah Elizabeth Waye

Arts & Sciences Graduate Student Theses and Dissertations

The small intestine in homeostasis is capable of regular regeneration, but in cases of massive injury like Short Bowel Syndrome, the innate human response often fails to fully compensate for the loss of nutrient absorptive surface area that accompanies bowel resection. Murine models display an active compensatory reaction deemed “adaptation” in which the surface area of the bowel is increased to accommodate nutrient absorptive needs. This observation has highlighted several gaps in knowledge regarding bowel adaptation. Firstly, what occurs on a molecular level in murine models during adaptation? Secondly, how can the findings in mice be applied to humans in …

On The Challenges And Rewards Of Analyzing Molecular Dynamics At The Terabyte And Millisecond Scale, Justin Roy Porter

Arts & Sciences Graduate Student Theses and Dissertations

Molecular Dynamics (MD) and Markov state models (MSMs) are powerful tools for estimating and concisely representing the conformational ensemble accessible to biological macromolecules, particularly proteins. Conformational ensembles are of special importance biological function, both in health and disease, because biology derives from molecules’ entire conformational distribution rather than any single structure. Consequently, MD is poised to become a powerful tool for personalized medicine and for the study of molecular sequence-function relationships generally. However, because of their hyperdimensionality and size, just generating MD datasets and Markov state models (MSMs) that represent biologically relevant molecules is a substantive technical challenge. Then, even …

Age-Dependent Search Behavior In The Colorado Checkered Whiptail (Aspidoscelis Neotesselatus), Carina Kusaka, Kaera Utsumi, Catherine Staley, Rachael Pedersen, Julia Valdivia, Elizabeth Liu, Hannah Caracalas, Hannah Reynolds, Maria A. Eifler, Douglas A. Eifler

Western North American Naturalist

We compared movement and space use patterns of foraging adult and juvenile Colorado checkered whiptails (Aspidoscelis neotesselatus) in pinyon pine–juniper woodland. Through focal observations, we characterized (1) movement paths as a series of step lengths and turn angles at 30-s intervals, and (2) habitat use reflected by the proportion of time spent in different vegetation types and in the open. Adults and juveniles differed in both movement and habitat use. Adults spent more time in the open and in association with mountain mahogany (Cercocarpus montanus), while juveniles were more frequently found in association with dead wood, …

Investigating Antimicrobial Properties Of Snake Venoms Against B. Cereus, B. Subtilis, E. Coli, And P. Vulgaris, Savannah Elaine Berger

Honors Program Theses and Research Projects

The increasing incidence of antibiotic resistant bacterial infections has provoked the attention of health officials and scientists as a major threat to global public health. Antibiotic resistance is the product of overprescription by doctors, ineffective or shortened dosing by the patient, and more. When a bacterial infection is ineffectively treated as such, persistent pathogenic cells are given the opportunity to proliferate and spread their resistance to other cells. With bacteria utilizing such tools to fight and ultimately resist our current treatment methods, investigation towards the next novel mechanism of inhibition is essential. Venom is of particular interest to many scientists …

Lrg1 Is An Adipokine That Mediates Obesity-Induced Hepatosteatosis And Insulin Resistance, Sijia He, Jiyoon Ryu, Juanhong Liu, Hairong Luo, Ying Lv, Paul R. Langlais, Jie Wen, Feng Dong, Zhe Sun, Ravindranath Duggirala

School of Medicine Publications

Dysregulation in adipokine biosynthesis and function contributes to obesity-induced metabolic diseases. However, the identities and functions of many of the obesity-induced secretory molecules remain unknown. Here, we report the identification of leucine-rich alpha-2-glycoprotein 1 (LRG1) as an obesity-associated adipokine that exacerbates high fat diet–induced hepatosteatosis and insulin resistance. Serum levels of LRG1 were markedly elevated in obese humans and mice compared with their respective controls. LRG1 deficiency in mice greatly alleviated diet-induced hepatosteatosis, obesity, and insulin resistance. Mechanistically, LRG1 bound with high selectivity to the liver and promoted hepatosteatosis by increasing de novo lipogenesis and suppressing fatty acid β-oxidation. LRG1 …

The Binary Oppositions In Joseph Conrad's Novel Heart Of Darkness, Huda Kadhim Alwan

Alustath Journal for Human and Social Sciences

The novel Heart of Darkness is regarded as one of Joseph Conrad's highly skilled works and seen as an important tale written between the years of 1898 - 1899, and also viewed as an assault on imperialism and unethical behaviors of the European colonizers in Africa in the nineteenth century. The novel displays the author's humanity towards the crimes of the colonists and imperialists throughout the world. In Heart of Darkness, Conrad shows the cruelty of colonialism in Africa through his major character, Charlie Marlow, who realizes the cruel manners of Belgian colonialism during his journey to the Congo …

Beach Hazards: Riu Funana, Cape Verde, C Stokes, G Masselink, T Scott, L Brodie

School of Biological and Marine Sciences

No abstract provided.

A Case Study On Hls Portability From Intel To Xilinx Fpgas, Zhili Xiao

McKelvey School of Engineering Graduate Student Theses & Dissertations

Field-programmable gate arrays (FPGAs) are a hardware accelerator option that is growing in popularity. However, FPGAs are notoriously hard to program. To this end, high-level synthesis (HLS) tools have been developed to allow programmers to design hardware accelerators with FPGAs using familiar software languages. The two largest FPGA vendors, Intel and Xilinx, support both C/C++ and OpenCL C to construct kernels. However, little is known about the portability of designs between these two platforms. In this work, we evaluate the portability and performance of Intel and Xilinx kernels. We conduct a case study, porting the Needleman-Wunsch application from the Rodinia …

Deep Learning For Automatic Microscopy Image Analysis, Shenghua He

McKelvey School of Engineering Graduate Student Theses & Dissertations

Microscopy imaging techniques allow for the creation of detailed images of cells (or nuclei) and have been widely employed for cell studies in biological research and disease diagnosis in clinic practices.Microscopy image analysis (MIA), with tasks of cell detection, cell classification, and cell counting, etc., can assist with the quantitative analysis of cells and provide useful information for a cellular-level understanding of biological activities and pathology. Manual MIA is tedious, time-consuming, prone to subject errors, and are not feasible for the high-throughput cell analysis process. Thus, automatic MIA methods can facilitate all kinds of biological studies and clinical tasks. Conventional …

Defining The Epigenetic And Transcriptional Regulatory Mechanisms By Which Hrsv Ns1 Alters Host Transcriptional Response, Nina Rose Beri

Arts & Sciences Graduate Student Theses and Dissertations

No abstract provided.

A Systematic Study Of Neutron Production In Two Versions Of The Mevion Proton-Therapy System, Nima Tatari

Arts & Sciences Graduate Student Theses and Dissertations

This thesis presents a study of neutron production in two types of proton-therapy systems: passive scattering Mevion S250, and active scanning Mevion S250i. The scattering system has been operating at Washington University in St. Louis since 2013. The scanning system was installed in the same building in 2020. The scanning system has the advantage of producing fewer neutrons due to a focused scanned beam and the absence of beam scatterers, collimators, and a static brass aperture. A systematic particle transport Monte Carlo analysis using the Geant4 toolkit has been performed to track the neutrons produced in various components of each …