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2021

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Phys 203-101: The Earth In Space, George Georgiou Sep 2021

Phys 203-101: The Earth In Space, George Georgiou

Physics Syllabi

No abstract provided.


Sts 210-101: Introduction To Psychology, Christopher Guarino Sep 2021

Sts 210-101: Introduction To Psychology, Christopher Guarino

Humanities Syllabi

No abstract provided.


Sts 210-103: Introduction To Psychology, Christopher Guarino Sep 2021

Sts 210-103: Introduction To Psychology, Christopher Guarino

Humanities Syllabi

No abstract provided.


Sts 201-H01: Understanding Technological Society, Narendra-Neel Khichi Sep 2021

Sts 201-H01: Understanding Technological Society, Narendra-Neel Khichi

Humanities Syllabi

No abstract provided.


Sts 360-451: Ethics And The Environment, Adam See Sep 2021

Sts 360-451: Ethics And The Environment, Adam See

Humanities Syllabi

No abstract provided.


Sts 360-453: Ethics And The Environment, Adam See Sep 2021

Sts 360-453: Ethics And The Environment, Adam See

Humanities Syllabi

No abstract provided.


Sts 342-451: Gender, Technology And Society, Nancy Steffen-Fluhr Sep 2021

Sts 342-451: Gender, Technology And Society, Nancy Steffen-Fluhr

Humanities Syllabi

No abstract provided.


Eng 340-101: Oral Presentation, Maximiliano Febles Sep 2021

Eng 340-101: Oral Presentation, Maximiliano Febles

Humanities Syllabi

No abstract provided.


September 1, 2021 Greenmail, University Of Alabama At Birmingham Sep 2021

September 1, 2021 Greenmail, University Of Alabama At Birmingham

GreenMail (student newsletter through 2024)

No abstract provided.


System Controls Of Coastal And Open Ocean Oxygen Depletion, Grant C. Pitcher, Arturo Aguirre-Velarde, Denise Breitburg, Jorge Cardich, Jacob Carstensen, Daniel J. Conley, Boris Dewitte, Anja Engel, Dante Espinoza-Morriberón, Georgina Flores, Véronique Garçon, Michelle Graco, Marilaure Grégoire, Dimitri Gutiérrez, José Martin Hernandez-Ayon, Huai Hsuan May Huang, Kirsten Isensee, María Elena Jacinto, Lisa Levin, Alberto Lorenzo, Eric Machu, Lander Merma, Ivonne Montes, Naqvi Swa, Aurelien Paulmier, Michael Roman, Kenneth Rose, Raleigh Hood, Nancy N. Rabalais, Anne Gro V. Salvanes, Renato Salvatteci, Sonia Sánchez, Abdelfettah Sifeddine Sep 2021

System Controls Of Coastal And Open Ocean Oxygen Depletion, Grant C. Pitcher, Arturo Aguirre-Velarde, Denise Breitburg, Jorge Cardich, Jacob Carstensen, Daniel J. Conley, Boris Dewitte, Anja Engel, Dante Espinoza-Morriberón, Georgina Flores, Véronique Garçon, Michelle Graco, Marilaure Grégoire, Dimitri Gutiérrez, José Martin Hernandez-Ayon, Huai Hsuan May Huang, Kirsten Isensee, María Elena Jacinto, Lisa Levin, Alberto Lorenzo, Eric Machu, Lander Merma, Ivonne Montes, Naqvi Swa, Aurelien Paulmier, Michael Roman, Kenneth Rose, Raleigh Hood, Nancy N. Rabalais, Anne Gro V. Salvanes, Renato Salvatteci, Sonia Sánchez, Abdelfettah Sifeddine

Faculty Publications

The epoch of the Anthropocene, a period during which human activity has been the dominant influence on climate and the environment, has witnessed a decline in oxygen concentrations and an expansion of oxygen-depleted environments in both coastal and open ocean systems since the middle of the 20th century. This paper provides a review of system-specific drivers of low oxygen in a range of case studies representing marine systems in the open ocean, on continental shelves, in enclosed seas and in the coastal environment. Identification of similar and contrasting responses within and across system types and corresponding oxygen regimes is shown …


Benthic Nutrient Fluxes Across Subtidal And Intertidal Habitats In Breton Sound In Response To River-Pulses Of A Diversion In Mississippi River Delta, Robert R. Twilley, Silke Rick, Daniel C. Bond, Justin Baker Sep 2021

Benthic Nutrient Fluxes Across Subtidal And Intertidal Habitats In Breton Sound In Response To River-Pulses Of A Diversion In Mississippi River Delta, Robert R. Twilley, Silke Rick, Daniel C. Bond, Justin Baker

Faculty Publications

We measured benthic fluxes of dissolved nutrients in subtidal sediments and intertidal soils associated with river-pulse events from Mississippi River via the operation of a river diversion struc-ture at Caernarvon, LA. Experiments measuring benthic fluxes in subtidal habitats were conducted during the early spring flood pulse (February and March) each year from 2002 to 2004, compared to benthic fluxes of intertidal habitats measured in February and March 2004. Nitrate (NO3−) uptake rates for subtidal sediments and intertidal soils depended on overlying water NO3− concentrations at near-, mid-, and far-field locations during river-pulse experiments when water temperatures were …


Integration Of Crop-Livestock Systems: An Opportunity To Protect Grasslands From Conversion To Cropland In The Us Great Plains, Alexander J. Smart, Daren Redfearn, Robert Mitchell, Tong Wang, Cody Zilverberg, Peter J. Bauman, Justin D. Derner, Julie Walker, Cody Wright Sep 2021

Integration Of Crop-Livestock Systems: An Opportunity To Protect Grasslands From Conversion To Cropland In The Us Great Plains, Alexander J. Smart, Daren Redfearn, Robert Mitchell, Tong Wang, Cody Zilverberg, Peter J. Bauman, Justin D. Derner, Julie Walker, Cody Wright

Native Plant Focused Publications

The Great Plains is a mixture of cropland and grassland mainly used for agricultural purposes, with grasslands under continual threat of conversion to cropland. Agriculturists are advocating for the integration of crop-livestock systems (ICLS) to recouple nutrient cycles, improve biodiversity, and increase resilience of agricultural operations. We address the benefits of ICLS in the Great Plains, contending that focus on improving soil health and financial stability of agricultural operations should reduce the conversion of grasslands to cropland. Using US Department of Agriculture National Agricultural Statistics Service Census of Agriculture survey data from the 1925−2017 category “cropland used only for pasture …


Keeping Nutrient Pollution At Bay: An Analysis Of Efforts To Mitigate Non-Point Source Pollution In The Chesapeake Bay, Madison Hinkle Sep 2021

Keeping Nutrient Pollution At Bay: An Analysis Of Efforts To Mitigate Non-Point Source Pollution In The Chesapeake Bay, Madison Hinkle

West Virginia Law Review

The Chesapeake Bay is one of the most important estuaries in the United States, adding to the region’s ecological, economic, recreational, historic, and cultural value. In 1982, a study was conducted that determined that a rapid loss of aquatic life in the Bay was due to nutrient pollution, specifically nitrogen and phosphorus, the majority of which is associated with the agricultural industry. A number of the jurisdictions2 within the Bay Watershed established the first Chesapeake Bay Agreement in 1983, aimed at abating the issues. Over the next four decades, the Agreement was then modified and resigned, additional jurisdictions have signed …


Aurora Kinase A Inhibition Reverses The Warburg Effect And Elicits Unique Metabolic Vulnerabilities In Glioblastoma, Trang T. T. Nguyen, Enyuan Shang, Chang Shu, Sungsoo Kim, Angeliki Mela, Nelson Humala, Aayushi Mahajan, Hee Won Yang, Hasan Orhan Akman, Catarina M. Quinzii, Guoan Zhang, Mike-Andrew Westhoff, Georg Karpel-Massler, Jeffrey N. Bruce, Peter Canoll, Markus D. Siegelin Sep 2021

Aurora Kinase A Inhibition Reverses The Warburg Effect And Elicits Unique Metabolic Vulnerabilities In Glioblastoma, Trang T. T. Nguyen, Enyuan Shang, Chang Shu, Sungsoo Kim, Angeliki Mela, Nelson Humala, Aayushi Mahajan, Hee Won Yang, Hasan Orhan Akman, Catarina M. Quinzii, Guoan Zhang, Mike-Andrew Westhoff, Georg Karpel-Massler, Jeffrey N. Bruce, Peter Canoll, Markus D. Siegelin

Publications and Research

Aurora kinase A (AURKA) has emerged as a drug target for glioblastoma (GBM). However, resistance to therapy remains a critical issue. By integration of transcriptome, chromatin immunoprecipitation sequencing (CHIP-seq), Assay for Transposase-Accessible Chromatin sequencing (ATAC-seq), proteomic and metabolite screening followed by carbon tracing and extracellular flux analyses we show that genetic and pharmacological AURKA inhibition elicits metabolic reprogramming mediated by inhibition of MYC targets and concomitant activation of Peroxisome Proliferator Activated Receptor Alpha (PPARA) signaling. While glycolysis is suppressed by AURKA inhibition, we note an increase in the oxygen consumption rate fueled by enhanced fatty acid oxidation (FAO), which was …


University Of Dayton Magazine, Autumn 2021, University Of Dayton Sep 2021

University Of Dayton Magazine, Autumn 2021, University Of Dayton

University of Dayton Alumni Publications

The University of Dayton Magazine is published quarterly by the Office of University Marketing and Communications for alumni, parents, students, faculty/staff, trustees and other friends of UD.


Targeting The Cdk6 Dependence Of Ph+ Acute Lymphoblastic Leukemia, Patrizia Porazzi, Marco De Dominici, Joseph Salvino, Bruno Calabretta Sep 2021

Targeting The Cdk6 Dependence Of Ph+ Acute Lymphoblastic Leukemia, Patrizia Porazzi, Marco De Dominici, Joseph Salvino, Bruno Calabretta

Department of Cancer Biology Faculty Papers

Ph+ ALL is a poor-prognosis leukemia subtype driven by the BCR-ABL1 oncogene, either the p190-or the p210-BCR/ABL isoform in a 70:30 ratio. Tyrosine Kinase inhibitors (TKIs) are the drugs of choice in the therapy of Ph+ ALL. In combination with standard chemotherapy, TKIs have markedly improved the outcome of Ph+ ALL, in particular if this treatment is followed by bone marrow transplantation. However, resistance to TKIs develops with high frequency, causing leukemia relapse that results in


The Legal Consequences Of Climate Change And The Durability Of U.S. Forest Service Sky Area Permits And Water Rights, Kiefer Armitage Stenseng Sep 2021

The Legal Consequences Of Climate Change And The Durability Of U.S. Forest Service Sky Area Permits And Water Rights, Kiefer Armitage Stenseng

Water Law Review

Water, an already scarce and valuable resource in the arid western United States, will only become more important as competing demands for water increase and water availability decreases. Lower precipitation driven by climate change is likely to worsen in the coming decades. The lasting impact of climate change can also manifest itself legally. Thus, the law operates to balance conflicting uses of water (and the associated rights) between public and private entities.

Differing views on the nature of property rights, particularly the nature of private nights in public resources, become determinative of how public and private interests should be balanced. …


Selective Serotonin Reuptake Inhibitors And Clozapine: Clinically Relevant Interactions And Considerations, Amber N. Edinoff, Juliana M. Fort, Joshua J. Woo, Christopher D. Causey, Caroline R. Burroughs, Elyse M. Cornett, Adam M. Kaye, Alan David Kaye Sep 2021

Selective Serotonin Reuptake Inhibitors And Clozapine: Clinically Relevant Interactions And Considerations, Amber N. Edinoff, Juliana M. Fort, Joshua J. Woo, Christopher D. Causey, Caroline R. Burroughs, Elyse M. Cornett, Adam M. Kaye, Alan David Kaye

School of Pharmacy Faculty Articles

The monoamine hypothesis of depression attributes the symptoms of major depressive disorders to imbalances of serotonin, noradrenaline, and dopamine in the limbic areas of the brain. The preferential targeting of serotonin receptor (SERT) by selective serotonin reuptake inhibitors (SSRIs) has offered an opportunity to reduce the range of these side effects and improve patient adherence to pharmacotherapy. Clozapine remains an effective drug against treatment-resistant schizophrenia, defined as failing treatment with at least two different antipsychotic medications. Patients with schizophrenia who display a constellation of negative symptoms respond poorly to antipsychotic monotherapy. Negative symptoms include the diminution of motivation, interest, or …


Mechanically Transduced Immunosorbent Assay To Measure Protein-Protein Interactions, Christopher J. Petell, Kathyrn Randene, Michael Pappas, Diego Sandoval, Brian Dstrahl, Joseph S. Harrison, Joshua P. Steimel Sep 2021

Mechanically Transduced Immunosorbent Assay To Measure Protein-Protein Interactions, Christopher J. Petell, Kathyrn Randene, Michael Pappas, Diego Sandoval, Brian Dstrahl, Joseph S. Harrison, Joshua P. Steimel

College of the Pacific Faculty Articles

Measuring protein-protein interaction (PPI) affinities is fundamental to biochemistry. Yet, conventional methods rely upon the law of mass action and cannot measure many PPIs due to a scarcity of reagents and limitations in the measurable affinity ranges. Here, we present a novel technique that leverages the fundamental concept of friction to produce a mechanical signal that correlates to binding potential. The mechanically transduced immunosorbent (METRIS) assay utilizes rolling magnetic probes to measure PPI interaction affinities. METRIS measures the translational displacement of protein-coated particles on a protein-functionalized substrate. The translational displacement scales with the effective friction induced by a PPI, thus …


Foundations Of Linguistics And Identity In L2 Teaching And Learning: Agency Through Linguistic Enrichment, Differentiated Instruction And Teacher Identity, Marnie Jo Petray, Rebecca Shapiro, Gladys M. Vega Sep 2021

Foundations Of Linguistics And Identity In L2 Teaching And Learning: Agency Through Linguistic Enrichment, Differentiated Instruction And Teacher Identity, Marnie Jo Petray, Rebecca Shapiro, Gladys M. Vega

Publications and Research

Language, procedure, and identity are L2 teaching/learning essentials that may promote agency and stimulate synergies among knowledge, practice, and reflection (Diaz Maggioli, 2014; Duff, 2012). This meta-report presents three studies that collectively advance agency and endorse linguistic foundations as enrichment, differentiated instruction as engagement, and teacher identity as empowerment. All of these theoretical constructs are key to successful L2 teaching and acquisition. Study 1 quantitatively reports on introductory linguistics’ presence or absence in 114 master’s programs at 54 US institutions. Findings suggest that linguistics’ curricular presence is inconsistent and training for optimal impact in the L2 classroom is lacking. Given …


Apologetics And Science Instruction For Educators In Secondary Christian Schools, Brett Austin Craddock Sep 2021

Apologetics And Science Instruction For Educators In Secondary Christian Schools, Brett Austin Craddock

Masters Theses

Without the incorporation of apologetic instruction into the science classroom students will be ill-equipped to defend the Christian faith. The academic world has seen a decrease of importance that is placed on the Christian mind and therefore the academic world and the majority of scholarly debates have been left to secular thinkers. Secondary Christian schools are in the optimal position to answer the need to raise up a generation of students that may apologetically and academically defend the Christian faith. Through including topics such as Intelligent Design, irreducible complexity, anatomy, and fine-tuning to various fields of science, secondary educators will …


Suits Against Gas-Emitting Landfills In West Virginia: Identifying And Overcoming The Barriers, Shawn H. Hogbin Sep 2021

Suits Against Gas-Emitting Landfills In West Virginia: Identifying And Overcoming The Barriers, Shawn H. Hogbin

West Virginia Law Review

The U.S. in the past two decades has experienced an increase in class actions stemming from landfill odors, with many of these lawsuits utilizing the common law doctrines of nuisance, trespass, and negligence. Landfill odors impact nearby residents, making it unenjoyable for them to be outside on their lawns, and even in their homes. West Virginia’s sole appellate court, despite the state having 17 operational landfills and disposing of nearly 1.5 million tons of trash, has seen no such suit. This Note identifies whether West Virginia decisional law is prohibitive of this type of suit; it finds no clear legal …


Season Of Prescribed Fire Determines Grassland Restoration Outcomes After Fire Exclusion And Overgrazing, Erin N. Novak, Michelle Bertelsen, Dick Davis, Devin M. Grobert, Kelly G. Lyons, Jason P. Martina, W. Matt Mccaw, Matthew O'Toole, Joseph W. Veldman Sep 2021

Season Of Prescribed Fire Determines Grassland Restoration Outcomes After Fire Exclusion And Overgrazing, Erin N. Novak, Michelle Bertelsen, Dick Davis, Devin M. Grobert, Kelly G. Lyons, Jason P. Martina, W. Matt Mccaw, Matthew O'Toole, Joseph W. Veldman

Biology Faculty Research

Fire exclusion and mismanaged grazing are globally important drivers of environmental change in mesic C4 grasslands and savannas. Although interest is growing in prescribed fire for grassland restoration, we have little long-term experimental evidence of the influence of burn season on the recovery of herbaceous plant communities, encroachment by trees and shrubs, and invasion by exotic grasses. We conducted a prescribed fire experiment (seven burns between 2001 and 2019) in historically fire-excluded and overgrazed grasslands of central Texas. Sites were assigned to one of four experimental treatments: summer burns (warm season, lightning season), fall burns (early cool season), winter …


This Red Line Goes Straight To Your Heart By Madhur Anand, Rita Kaur Dhamoon Sep 2021

This Red Line Goes Straight To Your Heart By Madhur Anand, Rita Kaur Dhamoon

The Goose

Review of Madhur Anand's This Red Line Goes Straight to Your Heart


Paul Perspectives, Fall 2021, Peter T. Paul College Of Business And Economics Sep 2021

Paul Perspectives, Fall 2021, Peter T. Paul College Of Business And Economics

Paul College Newsletters

No abstract provided.


Scaup Depredation On Arkansas Baitfish And Sportfish Aquaculture, Stephen A. Clements, Brian S. Dorr, J. Brian Davis, Luke A. Roy, Carole R. Engle, Katie Hanson-Dorr, Anita M. Kelly Sep 2021

Scaup Depredation On Arkansas Baitfish And Sportfish Aquaculture, Stephen A. Clements, Brian S. Dorr, J. Brian Davis, Luke A. Roy, Carole R. Engle, Katie Hanson-Dorr, Anita M. Kelly

United States Department of Agriculture Wildlife Services: Staff Publications

Lesser scaup (Aythya affinis) and greater scaup (A. marila), hereafter scaup, consume a variety of aquatic invertebrates, plants, and occasionally small fish. Scaup have foraged on commercial aquaculture farms in the southern United States for decades. However, the types, abundance, and rate of fish exploitation by scaup on baitfish and sportfish farms are not well documented. Thus, information is needed to understand how fish and other foods influence scaup use of aquatic resources, and any potential economic effects of depredation of fish. From November–March in winters 2016–2017 and 2017–2018, we conducted 1,458 pond surveys to …


In Situ Imaging Of Bacterial Outer Membrane Projections And Associated Protein Complexes Using Electron Cryo-Tomography, Mohammed Kaplan, Georges Chreifi, Lauren Ann Metskas, Janine Liedtke, Cecily R. Wood, Catherine M. Oikonomou, William J. Nicolas, Poorna Subramanian, Lori A. Zacharoff, Yuhang Wang, Yi-Wei Chang, Morgan Beeby, Megan J. Dobro, Yongtao Zhu, Mark J. Mcbride, Ariane Briegel, Carrie L. Shaffer, Grant J. Jensen Sep 2021

In Situ Imaging Of Bacterial Outer Membrane Projections And Associated Protein Complexes Using Electron Cryo-Tomography, Mohammed Kaplan, Georges Chreifi, Lauren Ann Metskas, Janine Liedtke, Cecily R. Wood, Catherine M. Oikonomou, William J. Nicolas, Poorna Subramanian, Lori A. Zacharoff, Yuhang Wang, Yi-Wei Chang, Morgan Beeby, Megan J. Dobro, Yongtao Zhu, Mark J. Mcbride, Ariane Briegel, Carrie L. Shaffer, Grant J. Jensen

Veterinary Science Faculty Publications

The ability to produce outer membrane projections in the form of tubular membrane extensions (MEs) and membrane vesicles (MVs) is a widespread phenomenon among diderm bacteria. Despite this, our knowledge of the ultrastructure of these extensions and their associated protein complexes remains limited. Here, we surveyed the ultrastructure and formation of MEs and MVs, and their associated protein complexes, in tens of thousands of electron cryo-tomograms of ~90 bacterial species that we have collected for various projects over the past 15 years (Jensen lab database), in addition to data generated in the Briegel lab. We identified outer MEs and MVs …


Rna Splicing Programs Define Tissue Compartments And Cell Types At Single-Cell Resolution, Julia E. Olivieri, Roozbeh Dehghannasiri, Peter Wang, Sori Jang, Antoine De Morree, Serena Y. Tan, Jingsi Ming, Angela R. Wu, Stephen R. Quake, Mark A. Krasnow, Julia Salzman Sep 2021

Rna Splicing Programs Define Tissue Compartments And Cell Types At Single-Cell Resolution, Julia E. Olivieri, Roozbeh Dehghannasiri, Peter Wang, Sori Jang, Antoine De Morree, Serena Y. Tan, Jingsi Ming, Angela R. Wu, Stephen R. Quake, Mark A. Krasnow, Julia Salzman

All Faculty Articles - School of Engineering and Computer Science

The extent splicing is regulated at single-cell resolution has remained controversial due to both available data and methods to interpret it. We apply the SpliZ, a new statistical approach, to detect cell-type-specific splicing in >110K cells from 12 human tissues. Using 10x data for discovery, 9.1% of genes with computable SpliZ scores are cell-type-specifically spliced, including ubiquitously expressed genes MYL6 and RPS24. These results are validated with RNA FISH, single-cell PCR, and Smart-seq2. SpliZ analysis reveals 170 genes with regulated splicing during human spermatogenesis, including examples conserved in mouse and mouse lemur. The SpliZ allows model-based identification of subpopulations indistinguishable …


2020 (32nd) Report Of The Nou Records Committee, Mark A. Brogie Sep 2021

2020 (32nd) Report Of The Nou Records Committee, Mark A. Brogie

Nebraska Bird Review

ebraska: 2017” (NOURC 2017).

Nebraska State List: The following includes all revisions made by the American Ornithological Society (Chesser et al. 2020) in 2020 including scientific name changes and taxonomic realignment that affect the current published “Official List of the Birds of Nebraska: 2017” (NOURC 2017, wwwNOUbirds.org). This report includes all accounts submitted during the 2020 calendar year covering 29 records with accession numbers 2258 – 2286.

2020 Additions/Deletions to the “Official List of the Birds of Nebraska”: Two new species were added in 2020.: Black Phoebe (Sayornis nigricans) 1. A single bird was photographed (Class 1-P, TL) 26 April …


Black-Throated Gray Warbler In Knox County, Nebraska, Mark A. Brogie Sep 2021

Black-Throated Gray Warbler In Knox County, Nebraska, Mark A. Brogie

Nebraska Bird Review

The Nebraska Ornithologists’ Union Records Committee (NOURC) considers Black-throated Gray Warbler (Setophaga nigrescens) to be Accidental in Nebraska (NOURC 2017). Silcock and Jorgensen (2020) list a total of seven accepted records with only two occurring in fall: an adult male at the Hyannis Cemetery, Grant Co., 01 Sep 2002 (Brogie 2003) and a female at Oliver Reservoir, Kimball Co., 07 Sep 2001 (Silcock 2001). The following documents the third Nebraska fall record for Black-throated Gray Warbler, the third record east of the Nebraska Panhandle, the first for northeast Nebraska, and the only NOURC accepted record (#2338) in the last decade.