Digital Commons Network^™

Weak Spatial-Genetic Structure In A Native Invasive, The Southern Pine Beetle (Dendroctonus Frontalis), Across The Eastern United States, Ryan C. Garrick, Ísis C. Arantes, Megan B. Stubbs, Nathan P. Havill

Faculty and Student Publications

The southern pine beetle, Dendroctonus frontalis, is a native pest of pine trees that has recently expanded its range into the northeastern United States. Understanding its colonization, dispersal, and connectivity will be critical for mitigating negative economic and ecological impacts in the newly invaded areas. Characterization of spatial-genetic structure can contribute to this; however, previous studies have reached different conclusions about regional population genetic structure, with one study reporting a weak east-west pattern, and the most recent reporting an absence of structure. Here we systematically assessed several explanations for the absence of spatial-genetic structure. To do this, we developed nine …

Growth And Feeding In The Sponge Agelas Tubulata From Shallow To Mesophotic Depths On Grand Cayman Island, Keir J. Macartney, Amelia Clayshulte Abraham, Marc Slattery, Michael P. Lesser

Faculty and Student Publications

On Caribbean coral reefs, sponges are important members of the benthic community and play multiple roles in ecosystem structure and function. They have an important role in benthic-pelagic coupling, consuming particulate organic matter (POM) and dissolved organic matter (DOM) and in turn providing food in the form of sponge biomass or the release of detritus for a variety of coral reef organisms. Throughout the Caribbean, sponges show consistent increases in their abundance and growth rates as depth increases into the mesophotic zone (30–150 m). This has been hypothesized to be driven by bottom-up forces, particularly the increased supply of nitrogen-rich …

Targeted Downregulation Of Myc Through G-Quadruplex Stabilization By Dnai, Alexandra Maria Psaras, Katarina T. Chang, Taisen Hao, Tracy A. Brooks

Faculty and Student Publications

Modulating the expression or function of the enigmatic MYC protein has demonstrated efficacy in an array of cancer types and a marked potential therapeutic index and safety profile. Despite its high therapeutic value, specific and selective inhibitors or downregulating therapeutics have proven difficult to develop. In the current study, we expanded our work on a MYC promoter G-quadruplex (G4) stabilizing DNA clamp to develop an oligonucleotide interfering DNA (DNAi) therapeutic. We explored six DNAi for G4-stabilization through EMSA, DMS footprinting, and thermal stability studies, focusing on the DNAi 5T as the lead therapeutic. 5T, but not its scramble control 5Tscr, …

Tissue-Specific Regulation Of Hnk-1 Biosynthesis By Bisecting Glcnac, Haruka Kawade, Jyoji Morise, Sushil K. Mishra, Shuta Tsujioka

Faculty and Student Publications

Human natural killer—1 (HNK-1) is a sulfated glyco-epitope regulating cell adhesion and synaptic functions. HNK-1 and its non-sulfated forms, which are specifically expressed in the brain and the kidney, respectively, are distinctly biosynthesized by two homologous glycosyltransferases: GlcAT-P in the brain and GlcAT-S in the kidney. However, it is largely unclear how the activity of these isozymes is regulated in vivo. We recently found that bisecting GlcNAc, a branching sugar in N-glycan, suppresses both GlcAT-P activity and HNK-1 expression in the brain. Here, we observed that the expression of non-sulfated HNK-1 in the kidney is unexpectedly unaltered in mutant mice …

Diary Of An Afghan Woman Collection - September 2021

TSOS Interview Gallery

Four women share with us their daily lives in Afghanistan. Join them as they express their love for the country, the people, and each other; and as they share with you their deepest fears and most intimate moments.

They refuse to be silenced as they journey through this new, uncharted chapter in Afghanistan's history.

We at TSOS are honored to provide a platform for their voices to be heard. We will post entries as we receive them. For safety purposes, names have been changed and only avatars (designed with input from each woman) will be used.

ZOYA

Zoya is a …

The Faculty Notebook, September 2021, Provost's Office

Faculty Notebook

The Faculty Notebook is published periodically by the Office of the Provost at Gettysburg College to bring to the attention of the campus community accomplishments and activities of academic interest. Faculty are encouraged to submit materials for consideration for publication to the Associate Provost for Faculty Development. Copies of this publication are available at the Office of the Provost.

Mathematical Modelling Of An Advection-Driven Interspecific Competition, Joel N. Ndam, Christian O. Akaluzia, Hilal Al Bayatti

Applied Mathematics & Information Sciences

An advection-driven interspecific competition model is constructed, which we believe is more physically realistic as the movements of competing species are usually aimed at a target. Standard analysis using the travelling wave approach was employed, and the results show that the equilibrium points are independent of the advection velocities and the wave speed. However, the stability of each steady state depends on the wave speed and the advection velocities of the competing species. Conditions for the extinction and coexistence of the species were also obtained and illustrated using numerical simulations. The implication for ecological resource management is also highlighted.

Symmetry Solutions And Conserved Quantities Of An Extended (1+3)-Dimensional Kadomtsev-Petviashvili- Like Equation, Oke Davies Adeyemo, Chaudry Masood Khalique

Applied Mathematics & Information Sciences

In this paper, we study an extended (1+3)-dimensional Kadomtsev-Petviashvili-like equation. Lie symmetry reductions of the equation were performed and direct integration technique was adopted. Kudryashov’s approach was utilized to generate a closed- form solution of the equation. Besides, we employ power series approach to secure a solution of the underlying equation. Solutions found for the underlying equation include hyperbolic function as well as series solutions of the equation. In conclusion, we construct conserved quantities of the aforementioned equation by invoking Ibragimov’s theorem.

Late Miocene Onset Of Tasman Leakage And Southern Hemisphere Supergyre Ushers In Near-Modern Circulation, Beth A. Christensen, David De Vleeschouwer, Jorijntje Henderiks, Jeroen Groeneveld, Gerald Auer, Anna Joy Drury, Boris Theofanis Karatsolis, Jing Lyu, Christian Betzler, Gregor P. Eberli, Dick Kroon

School of Earth & Environment Departmental Research

This study provides a Miocene-to-recent history of Tasman Leakage (TL), driving surfaceto-intermediate waters from the Pacific into the Indian Ocean. TL, in addition to Indonesian ThroughFlow (ITF), constitutes an important part of the Southern Hemisphere Supergyre. Here, we employ deep-sea benthic δ13C timeseries from the southwestern Pacific and eastern Indian Oceans to identify the history of Tasman Leakage. The δ13C results combined with sedimentary evidence show that an inter-ocean connection south of Australia existed from 7 Ma onward. A southward shift in Westerlies combined with a northward movement of Australia created the oceanic corridor necessary for Tasman Leakage (between Australia …

Uba2 Variants Underlie A Recognizable Syndrome With Variable Aplasia Cutis Congenita And Ectrodactyly, Rhonda E Schnur, Sairah Yousaf, James Liu, Wendy K Chung, Lindsay Rhodes, Michael Marble, Regina M Zambrano, Nara Sobreira, Parul Jayakar, Mary Ella Pierpont, Matthew J Schultz, Pavel N Pichurin, Rory J Olson, Gail E Graham, Matthew Osmond, Gustavo A Contreras-García, Karina A Campo-Neira, Camilo A Peñaloza-Mantilla, Mark Flage, Srikar Kuppa, Karina Navarro, Maria J Guillen Sacoto, Ingrid M Wentzensen, Maria I Scarano, Jane Juusola, Carlos E Prada, Robert B Hufnagel

Pediatrics Research and Scholarship

PURPOSE: The human chromosome 19q13.11 deletion syndrome is associated with a variable phenotype that includes aplasia cutis congenita (ACC) and ectrodactyly as specific features. UBA2 (ubiquitin-like modifier-activating enzyme 2) lies adjacent to the minimal deletion overlap region. We aimed to define the UBA2-related phenotypic spectrum in humans and zebrafish due to sequence variants and to establish the mechanism of disease.

METHODS: Exome sequencing was used to detect UBA2 sequence variants in 16 subjects in 7 unrelated families. uba2 loss of function was modeled in zebrafish. Effects of human missense variants were assessed in zebrafish rescue experiments.

RESULTS: Seven human UBA2 …

Alterations In The Leaf Lipidome Of Brassica Carinata Under High-Temperature Stress, Zolian Zoong Lwe, Saroj Sah, Leelawatti Persaud, Jiaxu Li, Wei Gao, K. Raja Reddy, Sruthi Narayanan

Open Access Publishing Fund

Background: Brassica carinata (A) Braun has recently gained increased attention across the world as a sustainable biofuel crop. B. carinata is grown as a summer crop in many regions where high temperature is a significant stress during the growing season. However, little research has been conducted to understand the mechanisms through which this crop responds to high temperatures. Understanding traits that improve the high-temperature adaption of this crop is essential for developing heat-tolerant varieties. This study investigated lipid remodeling in B. carinata in response to high-temperature stress. A commercial cultivar, Avanza 641, was grown under sunlit-controlled environmental conditions in Soil-Plant-Atmosphere-Research …

Microbial Communities In A Serpentinizing Aquifer Are Assembled Through Strong Concurrent Dispersal Limitation And Selection, Lindsay I. Putman, Mary C. Sabuda, William J. Brazelton, Michael D. Kubo, Tori M. Hoehler, Tom M. Mccollom, Dawn Cardace, Matthew O. Schrenk

Geosciences Faculty Publications

In recent years, our appreciation of the extent of habitable environments in Earth's subsurface has greatly expanded, as has our understanding of the biodiversity contained within. Most studies have relied on single sampling points, rather than considering the long-term dynamics of subsurface environments and their microbial populations. One such habitat are aquifers associated with the aqueous alteration of ultramafic rocks through a process known as serpentinization. Ecological modeling performed on a multiyear time series of microbiology, hydrology, and geochemistry in an ultrabasic aquifer within the Coast Range Ophiolite reveals that community assembly is governed by undominated assembly (i.e., neither stochastic …

2021-2022 Ursinus College Course Catalogue, Office Of The Registrar

Ursinus College Catalogues, 1869-Present

A digital copy of the 2021-2022 Ursinus College Catalog. It contains details of the curriculum, departmental requirements and courses of instruction as well as the Open Questions core requirements, experiential learning and the Common Intellectual Experience (CIE). Academic policies, special opportunities and scholarships, off-campus programs and graduation requirements are also outlined.

Odei Pathways, Office Of Diversity, Equity, And Inclusion

Newsletters

Greetings 1-2

Latinx/Hispanic Heritage Month September 15 to October 15 2

Equity Fellows Introductions: Members of ODEI Extended Extended Team 3-5

Faculty Cluster Hiring 5

Moving Beyond Bias 5-6

Anti-Racism Action Plan 7

Freshman Orientation 7

DEI Professional Development At HSU 7

Cross-Cultural Conversations 7

University Police

PD Day

Social Work

University Senate

English

equity arcata 8

Collaborative Network Analyst 8

PSCI 381S 8

Whiteness Accountability Space 9

TK-12 Equity Partnership Funding Ends 9

Ways to Engage: 10

ODEI Training Calendar 10

Serving on a Search Committee Soon? Check Your AUB Status 10

equity arcata Book Club: The Sum of …

Bioplastics In The Consumer Market, Elena Strom

Master of Science in Environmental Sciences and Management Projects

The global production and mismanagement of plastic has led to plastics deposited and scatted across marine environments. Conventional plastic, which most Americans encounter every day, is produced from fossil fuels and lacks the ability to fully break down upon disposal, breaking down into microplastics that can remain in the natural environment for hundreds of years. Moving away from petroleum-based plastics could lead to a reduction in greenhouse gas emissions and decrease plastic particles in the ocean. Based on existing literature, there are three biopolymers that could serve as replacements to conventional plastics in the marketplace. These biopolymers are seen as …

Silicon Foliar Spray And Substrate Drench Effects On Plant Growth, Morphology, And Resistance To Wilting With Container-Grown Edible Species, Joshua Tebow, Lauren L. Houston, Ryan W. Dickson

Horticulture Faculty Publications and Presentations

The objective of this study was to evaluate silicon (Si) foliar spray and substrate drench effects on plant growth and morphology for container-grown edible crops during greenhouse production, as well as resistance to plant wilting during post-production. In the first greenhouse experiment, basil received Si foliar sprays at 0, 50, 100, 200, and 400 mg∙L^–1 Si. In the second greenhouse experiment, Si was applied as either a foliar spray (500 mg∙L–1 Si) or substrate drench (100 mg∙L^–1 Si) with six edible crop species. Supplemental Si increased shoot Si levels but had minimal effects on plant growth and morphology, …

Linking Ecomechanical Models And Functional Traits To Understand Phenotypic Diversity, T. E. Higham, L. A. Ferry, L. Schmitz, D. J. Irschick, S. Starko, P. S L Anderson, P. J. Bergmann, H. A. Jamniczky, L. R. Monteiro, D. Navon, J. Messier, E. Carrington, S. C. Farina, K. L. Feilich, L. P. Hernandez, Michele A. Johnson, S. M. Kawano, C. J. Law, S. J. Longo, C. H. Martin, P. T. Martone, A. Rico-Guevara, S. E. Santana, K. J. Niklas

Biology Faculty Research

Physical principles and laws determine the set of possible organismal phenotypes. Constraints arising from development, the environment, and evolutionary history then yield workable, integrated phenotypes. We propose a theoretical and practical framework that considers the role of changing environments. This 'ecomechanical approach' integrates functional organismal traits with the ecological variables. This approach informs our ability to predict species shifts in survival and distribution and provides critical insights into phenotypic diversity. We outline how to use the ecomechanical paradigm using drag-induced bending in trees as an example. Our approach can be incorporated into existing research and help build interdisciplinary bridges. Finally, …

Freedom Of Will, Physics, And Human Intelligence: An Idea, Miroslav Svitek, Vladik Kreinovich, Nguyen Hoang Phuong

Departmental Technical Reports (CS)

Among the main fundamental challenges related to physics and human intelligence are: How can we reconcile the free will with the deterministic character of physical equations? What is the physical meaning of extra spatial dimensions needed to make quantum physics consistent? and Why are we often smarter than brain-simulating neural networks? In this paper, we show that while each of these challenges is difficult to resolve on its own, it may be possible to resolve all three of them if we consider them together. The proposed possible solution is that human reasoning uses the extra spatial dimensions. This may sound …

Positive Psychological Transformation: A Mixed Methods Investigation Into Catalysts And Processes Of Meaningful Change, Nick Fortino, Paul Dommert Jr., Nadia Santiago, Jen Smith

International Journal of Transpersonal Studies

This mixed methods study investigated the experience of positive psychological transformation, including its catalysts, dynamics, supportive factors, and outcomes. The first phase of the study was a 13-item survey (N=130) that revealed trends and associations in participants’ experiences of transformation. The most significant correlation was between “expressing myself” and change stabilization (p < .01). Forty-four percent of participants reported trauma or emotional distress as the main catalyst of their transformation. Each of the other three main catalysts (dissonance, adaptation, and inspiration) drew approximately 18% of responses. Connecting with nature (71%), introspection (65%), solitude (63%) and empathy (61%) were commonly reported supportive factors. Common changes related to participants’ way of interacting with others (77%), perception (75%), and emotional patterns (70%). The process of transformation differed substantially depending on multiple factors including the catalyst and demographic categories. Additionally, the survey revealed a trend of moving away from organized religion toward a sense of being spiritual but not religious. The second phase of the study consisted of interviews with a portion of the participants who reported trauma as the main catalyst of their transformation (n = 26) and was focused on the experience of posttraumatic growth. Thematic analysis revealed that transformation is typically initiated by a series of traumatic events and that the process of transformation can involve impaired well-being/functioning before elevated well-being/functioning. The results of thematic analysis were consistent with existing data on posttraumatic growth.

Farmers’ Adoption And Perceived Benefits Of Diversified Crop Rotations In The Margins Of U.S. Corn Belt, Tong Wang, Jin Hailong, Yubing Fan, Oladipo Obembe, Dapeng Li

Economics Faculty Publications

Monoculture and simplified two-crop rotation systems compromise the ecosystem services essential to crop production, diminish agricultural productivity, and cause detrimental effects on the environment. In contrast to the simplified two-crop rotation, diversified crop rotation (DCR) refers to rotation systems that contain three or more crops. Despite multiple benefits generated by DCR, its usage has dwindled over the past several decades. This paper examined determinants of farmers' adoption decisions and perceived benefits of DCR in the west margins of the U.S. Corn Belt where crop diversity has declined. We analyzed 708 farmer responses from a farmer survey conducted in the eastern …

No Bones About Art, Lydia Lytal, Brooke A. Whitworth, Gail Morton

Publications

No abstract provided.

Simulated Wildfire Smoke Significantly Alters Sperm Dna Methylation Patterns In A Murine Model, Adam Schuller, Chiara Bellini, Timothy G. Jenkins, Matthew Eden, Jacqueline Matz, Jessica Oakes, Luke Montrose

Public and Population Health Faculty Publications and Presentations

Wildfires are now a common feature of the western US, increasing in both intensity and number of acres burned over the last three decades. The effects of this changing wildfire and smoke landscape are a critical public and occupational health issue. While respiratory morbidity due to smoke exposure is a priority, evaluating the molecular underpinnings that explain recent extrapulmonary observations is necessary. Here, we use an Apoe^−/− mouse model to investigate the epigenetic impact of paternal exposure to simulated wildfire smoke. We demonstrate that 40 days of exposure to smoke from Douglas fir needles induces sperm DNA methylation changes …

Men's Golf Media Guide 2021-22, Wofford College. Department Of Athletics

Media Guides

No abstract provided.

Cross Country-Track And Field Media Guide 2021-2022, Wofford College. Department Of Athletics

Media Guides

No abstract provided.

Amjambo Africa! (September 2021), Kathreen Harrison

Amjambo Africa!

In this Issue

Afghanistan..........................2/39

Burundi/Cameroon.....3/34 - 35

Education . ...........................4 - 9

Publshers Editorial Afghanistan.........................10

Translations........................11-13

World Market Basket........14/15

African Weddings...................16

Beautiful Blackbird Children’s Festival.................................17

Columns...18/19/31

New!

Health&Wellness...............22-30 Covid-19 and Delta variant In English & translation

New!

New Voices.........................32/33

Columnists

Kifah Abdullah,

Rupal Ramesh Shah,

Roseline Souebele

Nsiona Nguizani

Gashi

In honor of National Hispanic Heritage Month!......................39

Maine organizations serving Spanish speakers...

Spanish coming in October!

Placenta-Specific Slc38a2/Snat2 Knockdown Causes Fetal Growth Restriction In Mice, Owen R. Vaughan, Katarzyna Maksym, Elena Silva, Kenneth Barentsen, Russel V. Anthony, Sara L. Hillman, Thomas L. Brown, Rebecca Spencer, Anna L. David, Fredrick J. Rosario, Theresa L. Powell, Thomas Jansson

Neuroscience, Cell Biology & Physiology Faculty Publications

Fetal growth restriction (FGR) is a complication of pregnancy that reduces birth weight, markedly increases infant mortality and morbidity and is associated with later-life cardiometabolic disease. No specific treatment is available for FGR. Placentas of human FGR infants have low abundance of sodium-coupled neutral amino acid transporter 2 (Slc38a2/SNAT2), which supplies the fetus with amino acids required for growth. We determined the mechanistic role of placental Slc38a2/SNAT2 deficiency in the development of restricted fetal growth, hypothesizing that placenta-specific Slc38a2 knockdown causes FGR in mice. Using lentiviral transduction of blastocysts with a small hairpin RNA (shRNA), we achieved 59% knockdown of …

Linfield University Catalog, 2021-2022, Linfield Archives

Student Course Catalogs

No abstract provided.

Incidence Of Yersinia Enterocolitica In Raw Farm And Market Milk Sample, Marwa Eltoukhy, Mohammed El-Sayed, Aisha Shoeib

Mansoura Veterinary Medical Journal

Objectives: This study was applied to investigate the incidence of Yersinia enterocolitica in raw farm and market milk and studying the quality drawbacks which might happen in milk as a result of its existence. Design: Observation study. Samples:Onehundred raw milk samples. Procedures: Fifty bulk tank milk (BTM), 25 individual milk & 25 market milk samples were collected from various dairy farms and supermarkets in Dakahlia Governorate, Egypt. The quality assessment of the samples began with evaluating the milk physical characteristics including color, odor, pH and the titratable acidity that reflected the hygienic quality of milk production on farm levels. Then …

The Effects Of Family Structure Stability And Parenting Practices On Juvenile Delinquency: Variations By Immigrant Generational Status And Race/Ethnicity, Lanmeng Ma

Doctoral Works at the University of New Haven

While the important role of various psychosocial factors in the development of criminality has long been acknowledged, many researchers, criminologists and criminal justice professionals firmly believe that family is specifically at the core. The purpose of this dissertation is to examine the relationships among family structure stability, parenting practice dimensions, and concurrent/subsequent delinquent behaviors, both theoretically and empirically. This study investigates how immigrant generational status and racial/ethnic disparities modulate associations between the stability of family structure, aspects of parenting practices, and adolescent delinquency, using a nationally representative sample from the National Longitudinal Study of Adolescent to Adult Health (Add Health). …

Loss Of Synergistic Transcriptional Feedback Loops Drives Diverse B-Cell Cancers, Jared M Andrews, Sarah C Pyfrom, Jennifer A Schmidt, Olivia I Koues, Rodney A Kowalewski, Nicholas R Grams, Jessica J Sun, Leigh R Berman, Eric J Duncavage, Yi-Shan Lee, Amanda F Cashen, Eugene M Oltz, Jacqueline E Payton

Open Access Publications

BACKGROUND: The most common B-cell cancers, chronic lymphocytic leukemia/lymphoma (CLL), follicular and diffuse large B-cell (FL, DLBCL) lymphomas, have distinct clinical courses, yet overlapping "cell-of-origin". Dynamic changes to the epigenome are essential regulators of B-cell differentiation. Therefore, we reasoned that these distinct cancers may be driven by shared mechanisms of disruption in transcriptional circuitry.

METHODS: We compared purified malignant B-cells from 52 patients with normal B-cell subsets (germinal center centrocytes and centroblasts, naïve and memory B-cells) from 36 donor tonsils using >325 high-resolution molecular profiling assays for histone modifications, open chromatin (ChIP-, FAIRE-seq), transcriptome (RNA-seq), transcription factor (TF) binding, and …