Digital Commons Network^™

Matchstick Keeper, Jona L. Pedersen

Floodwall Magazine

No abstract provided.

Weather Vane, Jona L. Pedersen

Floodwall Magazine

No abstract provided.

At The End Of The Path, Jona Pedersen, Wyatt Atchley

Floodwall Magazine

No abstract provided.

Polyelectrolyte Microgels As Self-Defensive Biomaterials, Matthew Libera

Amgen Seminar Series in Chemical Engineering

Preventing the bacterial colonization of tissue-contacting biomedical devices is a key scientific challenge rich with potential clinical impact. Much research has concentrated on antimicrobial modification of device surfaces either by incorporating continuous elution mechanisms or by covalent surface tethering. Both strategies have shortcomings. As an alternative, we are studying a microgel-based approach to modulate the antimicrobial properties of surfaces. Notably, polyelectrolyte microgels can be electrostatically deposited to form sub-monolayer microgel coatings on complex 3-D devices. We have shown that the size and spatial distribution of antifouling PEG-based microgels critically controls the competing requirements for bacterial repulsion and tissue-cell adhesion/proliferation. Incorporating …

Converging Andragogy With Working Adult Professionalism In Initial Teacher Preparation, Michelle Anderson, Stefani Boutelier

Journal of Educational Research and Practice

Educator Preparation Programs (EPPs) are tasked with providing preservice teachers with pedagogical theory, practical field experiences, mentorship, and scaffolded professional dispositions during critical phases of their preparation. In addition, EPPs collaborate with school districts and state departments of education to address critical issues in the field, including teacher retention and shortages. Our research explores how one EPP pilot, designed to build upon experience, supported working adult education students (e.g., parapros) seeking initial teacher certification. We sought to understand how adult teacher candidates engaged in professional learning and emergent professional relationships. Our qualitative study examined the experience of the first cohort …

Reproductive Aging In Caenorhabditis Elegans: From Molecules To Ecology, Andrea Scharf, Franziska Pohl, Brian M. Egan, Zuzana Kocsisova, Kerry Kornfeld

Biological Sciences Faculty Research & Creative Works

Aging animals display a broad range of progressive degenerative changes, and one of the most fascinating is the decline of female reproductive function. In the model organism Caenorhabditis elegans, hermaphrodites reach a peak of progeny production on day 2 of adulthood and then display a rapid decline; progeny production typically ends by day 8 of adulthood. Since animals typically survive until day 15 of adulthood, there is a substantial post reproductive lifespan. Here we review the molecular and cellular changes that occur during reproductive aging, including reductions in stem cell number and activity, slowing meiotic progression, diminished Notch signaling, and …

Harness Organoid Models For Virological Studies In Animals: A Cross-Species Perspective, Yongming Sang, Laura C. Miller, Rahul K. Nelli, Luis Gabriel Giménez-Lirola

Agricultural and Environmental Sciences Faculty Research

Animal models and cell culture in vitro are primarily used in virus and antiviral immune research. Whereas the limitation of these models to recapitulate the viral pathogenesis in humans has been made well aware, it is imperative to introduce more efficient systems to validate emerging viruses in both domestic and wild animals. Organoids ascribe to representative miniatures of organs (i.e., mini-organs), which are derived from three-dimensional culture of stem cells under respective differential conditions mimicking endogenous organogenetic niches. Organoids have broadened virological studies in the human context, particularly in recent uses for COVID19 research. This review examines the status and …

Did Pa. Supreme Court Justice David Wecht Herald The Death Of God?, Bruce Ledewitz

Newspaper Columns

Collected biweekly contributions to the Pennsylvania Capital-Star, a nonpartisan, nonprofit news site.

Computer Science Principles With C++, Seth D. Bergmann

Open Educational Resources

This textbook is intended to be used for a first course in computer science, such as the College Board’s Advanced Placement course known as AP Computer Science Principles (CSP). This book includes all the topics on the CSP exam, plus some additional topics. It takes a breadth-first approach, with an emphasis on the principles which form the foundation for hardware and software. No prior experience with programming should be required to use this book. This version of the book uses the C++ programming language.

Two University Of Dayton Alumni Awarded Fulbright Scholarships, Allison Brace

College of Arts and Sciences Newsroom

With recent nominees Olivia LeBlanc and Elizabeth Michalenko, the University of Dayton has now produced 37 Fulbright Scholars since 2002.

Blood Biomarkers For Mild Traumatic Brain Injury: A Selective Review Of Unresolved Issues, Daniel B. Hier, Tayo Obafemi-Ajayi, Matthew S. Thimgan, Gayla R. Olbricht, Sima Azizi, Blaine Allen, Bassam A. Hadi, Donald C. Wunsch

College of Natural and Applied Sciences

Background: The use of blood biomarkers after mild traumatic brain injury (mTBI) has been widely studied. We have identified eight unresolved issues related to the use of five commonly investigated blood biomarkers: neurofilament light chain, ubiquitin carboxy-terminal hydrolase-L1, tau, S100B, and glial acidic fibrillary protein. We conducted a focused literature review of unresolved issues in three areas: mode of entry into and exit from the blood, kinetics of blood biomarkers in the blood, and predictive capacity of the blood biomarkers after mTBI.

Findings: Although a disruption of the blood brain barrier has been demonstrated in mild and severe traumatic brain …

Molecular Classification Improves Risk Assessment In Adult Bcr-Abl1-Negative B-All, Elisabeth Paietta, Kathryn G. Roberts, Victoria Wang, Zhaohui Gu, Georgina A N Buck, Deqing Pei, Cheng Cheng, Ross L. Levine, Omar Abdel-Wahab, Zhongshan Cheng, Gang Wu, Chunxu Qu, Lei Shi, Stanley Pounds, Cheryl L. Willman, Richard Harvey, Janis Racevskis, Jan Barinka, Yanming Zhang, Gordon W. Dewald, Rhett P. Ketterling, David Alejos, Hillard M. Lazarus, Selina M. Luger, Letizia Foroni, Bela Patel, Adele K. Fielding, Ari Melnick, David I. Marks, Anthony V. Moorman, Peter H. Wiernik, Jacob M. Rowe, Martin S. Tallman, Anthony H. Goldstone, Charles G. Mullighan, Mark R. Litzow

Pathology Research and Scholarship

Genomic classification has improved risk assignment of pediatric, but not adult B-lineage acute lymphoblastic leukemia (B-ALL). The international UKALLXII/ECOG-ACRIN E2993 (#NCT00002514) trial accrued 1229 adolescent/adult patients with BCR-ABL1- B-ALL (aged 14 to 65 years). Although 93% of patients achieved remission, 41% relapsed at a median of 13 months (range, 28 days to 12 years). Five-year overall survival (OS) was 42% (95% confidence interval, 39, 44). Transcriptome sequencing, gene expression profiling, cytogenetics, and fusion polymerase chain reaction enabled genomic subtyping of 282 patient samples, of which 264 were eligible for trial, accounting for 64.5% of E2993 patients. Among patients with outcome …

A Gentleman's Guide To Love And Murder, Otterbein Theatre And Dance Department

2021-2022 Season Production

Join us as we celebrate a return to live theater with a very special staged concert version of the show that was cancelled due to the COVID-19 pandemic in March of 2020. While we are unable to fully realize the elaborate design of this hilarious knock-em-dead musical romp, the script will be performed in full with much of the original cast, and you will not leave without having a hearty laugh. Poor, low-born Monty Navarro is desperate to inherit the dukedom by surpassing no fewer than eight members of the well-to-do D’Ysquith family in line before him. Just wait until …

Conquer And Prevail Issue 80 September 16 2021, Wofford College. Office Of Marketing And Communications

Conquer and Prevail Newsletter

No abstract provided.

Chen Wins A Va Senior Research Career Scientist Award, Jeff Hansen

Browse All News

No abstract provided.

Daily Eastern News: September 16, 2021, Eastern Illinois University

September

No abstract provided.

Moving On Up: Vertical Distribution Shifts In Rocky Reef Fish Species During Climate-Driven Decline In Dissolved Oxygen From 1995 To 2009, Erin L. Meyer-Gutbrod, Li Kui, Mary Nishimoto, Linda Snook, Milton Love

Faculty Publications

Anthropogenic climate change has resulted in warming temperatures and reduced oxygen concentrations in the global oceans. Much remains unknown on the impacts of reduced oxygen concentrations on the biology and distribution of marine fishes. In the Southern California Channel Islands, visual fish surveys were conducted frequently in a manned submersible at three rocky reefs between 1995 and 2009. This area is characterized by a steep bathymetric gradient, with the surveyed sites Anacapa Passage, Footprint and Piggy Bank corresponding to depths near 50, 150 and 300 m. Poisson models were developed for each fish species observed consistently in this network of …

Unh Research Finds Witnessing Abuse Of Sibling Can Lead To Mental Health Issues, Robbin Ray

Media Relations

No abstract provided.

Sea Otter Effects On Trophic Structure Of Seagrass Communities In Southeast Alaska, Wendel W. Raymond, Julie B. Schram, Ginny L. Eckert, Aaron W. Galloway

Faculty, Staff, and Students

Previous research in southeast Alaska on the effects of sea otters Enhydra lutris in seagrass Zostera marina communities identified many but not all of the trophic relationships that were predicted by a sea otter-mediated trophic cascade. To further resolve these trophic connections, we compared biomass, carbon (δ13C) and nitrogen (δ15N) stable isotope (SI), and fatty acid (FA) data from 16 taxa at 3 sites with high and 3 sites with low sea otter density (8.2 and 0.1 sea otters km−2, respectively). We found lower crab and clam biomass in the high sea otter region but did not detect a difference …

Whalesong 2021-09-16 (V.41 No.5), Mike Flunker, Margaret Everson, Sierra Lissick, Jon Calleja, Ryan Sand, Kenedy Williams, Becky Iverson

Whalesong

No abstract provided.

Bird Courtship Rituals Topic For Virtual Science Cafe, Edwin B. Smith

University of Mississippi News

Neuroscience professor to discuss manakin study during Sept. 21 Zoom event

The Concise Guide To Pharmacology 2021/22: Enzymes, Stephen Ph Alexander, Doriano Fabbro, Eamonn Kelly, Alistair Mathie, John A. Peters, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Adam J. Pawson, Christopher Southan, James A. Davies, Detlan Boison, Kathryn Elisa Burns, Carmen Dessauer, Jürg Gertsch, Nuala Ann Helsby, Angela A. Izzo, Doris Koesling, Rennolds Ostrom, Nigel J. Pyne, Susan Pyne, Michael Russwurm, Roland Seifert, Johannes-Peter Stasch, Mario Van Der Stelt, Albert Van Der Vliet, Val Watts, Szu Shen Wong

Pharmacy Faculty Articles and Research

The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of nearly 1900 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes over 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record …

Unh Research Finds Witnessing Abuse Of Sibling Can Lead To Mental Health Issues, Robbin Ray

UNH Today Archive

No abstract provided.

The Montclarion, September 16, 2021, The Montclarion

The Montclarion

Student Newspaper of Montclair State University

Genetic Counseling As Preventive Intervention: Toward Individual Specification Of Transgenerational Autism Risk, Natasha Marrus, Tychele N Turner, Elizabeth Forsen, Drew Bolster, Alison Marvin, Andrew Whitehouse, Laura Klinger, Christina A Gurnett, J N Constantino

2020-Current year OA Pubs

BACKGROUND: Although autism spectrum disorders (ASD) are among the most heritable of all neuropsychiatric syndromes, most affected children are born to unaffected parents. Recently, we reported an average increase of 3-5% over general population risk of ASD among offspring of adults who have first-degree relatives with ASD in a large epidemiologic family sample. A next essential step is to investigate whether there are measurable characteristics of individual parents placing them at higher or lower recurrence risk, as this information could allow more personalized genetic counseling.

METHODS: We assembled what is to our knowledge the largest collection of data on the …

Evaluating The Structure, Demographics, And Effectiveness Of The Mississippi Master Naturalist Program, Sarah Cunningham, Eric Sparks, Adam Rohnke

Journal of Extension

The purpose of our evaluation was to assess the structure, demographics, and effectiveness of the Mississippi Master Naturalist Program (MMNP) from 2015-2019. Results show that racial diversity within the MMNP was low and offering basic training courses during the work week attracts more retirees. Subsequently, an average retiree completed nearly three times more annual volunteer service hours than a non-retiree. Therefore, targeting retirees may be the most effective means of enhancing environmental stewardship within this program. Additionally, the results of this evaluation highlight that active recruitment of underserved populations is necessary to increase the diversity of participants in Extension programs.

The Cowl - V. 86 N. 2 - Sep 16, 2021

The Cowl

The Cowl - student newspaper of Providence College. Vol. 86 No. 2 - September 16, 2021. 20 pages.

Multivariate Statistical Analysis Applied To The Forensic Analysis Of Synthetic Fibers, Abdulrahman Aljanaahi

Theses

Textile fibers obtained from crime scenes can provide trace evidence to help solve criminal cases through forensic science. Examining the samples involves the use of different analytical procedures to determine associations between different fabric fragments. The current study explored multivariate statistical methods applied in synthetic fiber forensic science comparisons. The literature review of the current research identified various multivariate approaches such as Principal Component Analysis (PCA) and Partial Least Square Discriminant Analysis (PLS-DA) to analyze spectroscopic and chromatographic data. The capstone project used Fourier Transform Infrared (FT-IR) Spectroscopy instrumental methods for the analysis of standard synthetic fibers. Afterwards, multivariate data …

Oral Microbiome And Gingival Gene Expression Of Inflammatory Biomolecules With Aging And Periodontitis, Jeffrey L. Ebersole, Radhakrishnan Nagarajan, Sreenatha Kirakodu, Octavio A. Gonzalez

Dental Medicine Faculty Research

Although data describe the presence and increase of inflammatory mediators in the local environment in periodontitis vs. health in humans, details regarding how these responses evolve in the transition from health to disease, changes during disease progression, and features of a resolved lesion remain unknown. This study used a nonhuman primate model of ligature-induced periodontitis in young, adolescent, adult, and aged animals to document features of inflammatory response affected by age. Rhesus monkeys had ligatures tied and provided gingival tissue biopsy specimens at baseline, 0.5, 1, and 3 months of disease and at 5 months of the study, which was …

The George-Anne Inkwell Edition, Georgia Southern University

The Inkwell

No abstract provided.