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2021

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Gambel Oak Care, Shawn Olsen, Debbie Amundsen, Shital Poudyal Sep 2021

Gambel Oak Care, Shawn Olsen, Debbie Amundsen, Shital Poudyal

All Current Publications

Gambel oak is commonly called scrub oak, but other common names are Rocky Mountain white oak and Utah white oak. The scientific name is Quercus gambelii, after William Gambel, an American naturalist. This fact sheet reviews Gambel oak's usability in the landscape, its care, growth requirements, diseases and pests, and maintenance.


The Ephb2 Receptor Uses Homotypic, Head-To-Tail Interactions Within Its Ectodomain As An Autoinhibitory Control Mechanism, Yan Xu, Dorothea Robev, Nayanendu Saha, Bingcheng Wang, Matthew B. Dalva, Kai Xu, Juha P. Himanen, Dimitar B. Nikolov Sep 2021

The Ephb2 Receptor Uses Homotypic, Head-To-Tail Interactions Within Its Ectodomain As An Autoinhibitory Control Mechanism, Yan Xu, Dorothea Robev, Nayanendu Saha, Bingcheng Wang, Matthew B. Dalva, Kai Xu, Juha P. Himanen, Dimitar B. Nikolov

Department of Neuroscience Faculty Papers

The Eph receptor tyrosine kinases and their ephrin ligands direct axon pathfinding and neuronal cell migration, as well as mediate many other cell–cell communication events. Their dysfunctional signaling has been shown to lead to various diseases, including cancer. The Ephs and ephrins both localize to the plasma membrane and, upon cell–cell contact, form extensive signaling assemblies at the contact sites. The Ephs and the ephrins are divided into A and B subclasses based on their sequence conservation and affinities for each other. The molecular details of Eph–ephrin recognition have been previously revealed and it has been documented that ephrin binding …


Supercoiling And Looping Promote Dna Base Accessibility And Coordination Among Distant Sites, Jonathan M Fogg, Allison K Judge, Erik Stricker, Hilda L Chan, Lynn Zechiedrich Sep 2021

Supercoiling And Looping Promote Dna Base Accessibility And Coordination Among Distant Sites, Jonathan M Fogg, Allison K Judge, Erik Stricker, Hilda L Chan, Lynn Zechiedrich

Faculty, Staff and Students Publications

DNA in cells is supercoiled and constrained into loops and this supercoiling and looping influence every aspect of DNA activity. We show here that negative supercoiling transmits mechanical stress along the DNA backbone to disrupt base pairing at specific distant sites. Cooperativity among distant sites localizes certain sequences to superhelical apices. Base pair disruption allows sharp bending at superhelical apices, which facilitates DNA writhing to relieve torsional strain. The coupling of these processes may help prevent extensive denaturation associated with genomic instability. Our results provide a model for how DNA can form short loops, which are required for many essential …


Thrombolytic Enzymes Of Microbial Origin: A Review, Deepti Diwan, Zeba Usmani, Minaxi Sharma, James W Nelson, Vijay Kumar Thakur, Graham Christie, Gustavo Molina, Vijai Kumar Gupta Sep 2021

Thrombolytic Enzymes Of Microbial Origin: A Review, Deepti Diwan, Zeba Usmani, Minaxi Sharma, James W Nelson, Vijay Kumar Thakur, Graham Christie, Gustavo Molina, Vijai Kumar Gupta

2020-Current year OA Pubs

Enzyme therapies are attracting significant attention as thrombolytic drugs during the current scenario owing to their great affinity, specificity, catalytic activity, and stability. Among various sources, the application of microbial-derived thrombolytic and fibrinolytic enzymes to prevent and treat vascular occlusion is promising due to their advantageous cost-benefit ratio and large-scale production. Thrombotic complications such as stroke, myocardial infarction, pulmonary embolism, deep venous thrombosis, and peripheral occlusive diseases resulting from blood vessel blockage are the major cause of poor prognosis and mortality. Given the ability of microbial thrombolytic enzymes to dissolve blood clots and prevent any adverse effects, their use as …


Enhancing Uptake Of Nature-Based Solutions For Informing Coastal Sustainable Development Policy And Planning: A Malaysia Case Study, Su Yin Chee, Louise B. Firth, Amy Yee Hui Then, Jean Chai Yee, Aazani Mujahid, Yang Amri Affendi, A. Aldrie Amir, Chai Ming Lau, Jillian Lean Sim Ooi, Yew Aun Quek, Choo Eng Tan, Tzuen Kiat Yap, Chin Aik Yeap, Abigail Mcquatters-Gollop Sep 2021

Enhancing Uptake Of Nature-Based Solutions For Informing Coastal Sustainable Development Policy And Planning: A Malaysia Case Study, Su Yin Chee, Louise B. Firth, Amy Yee Hui Then, Jean Chai Yee, Aazani Mujahid, Yang Amri Affendi, A. Aldrie Amir, Chai Ming Lau, Jillian Lean Sim Ooi, Yew Aun Quek, Choo Eng Tan, Tzuen Kiat Yap, Chin Aik Yeap, Abigail Mcquatters-Gollop

School of Biological and Marine Sciences

Nature-based Solutions (NbS) have been advocated to protect, sustainably manage, and restore natural or modified ecosystems, simultaneously providing human well-being and biodiversity benefits. The uptake of NbS differs regionally with some countries exhibiting greater uptake than others. The success of NbS also differs regionally with varying environmental conditions and social-ecological processes. In many regions, the body of knowledge, particularly around the efficacy of such efforts, remains fragmented. Having an “inventory” or “tool box” of regionally-trialed methods, outcomes and lessons learnt can improve the evidence base, inform adaptive management, and ultimately support the uptake of NbS. Using Malaysia as a case …


New Scholarship On Florida (2006-2007), Florida Historical Society Sep 2021

New Scholarship On Florida (2006-2007), Florida Historical Society

Florida Historical Quarterly

The Florida Historical Quarter4 is reinstituting an earlier practice of publishing an annual list of new scholarship on Florida History. The list contains books not reviewed in the Quarterly, articles published in journals other than the Florida Historical Quarterly, chapters on Florida that appeared in edited books of essays, and theses and dissertations. The 2006-2007 list was compiled by Ryan D. Groves.


Eating The Claws Of Eden: Stone Crabs, Tourism, And The Taste Of Conservation In Florida And Beyond, Florida Historical Society Sep 2021

Eating The Claws Of Eden: Stone Crabs, Tourism, And The Taste Of Conservation In Florida And Beyond, Florida Historical Society

Florida Historical Quarterly

Don't miss the stone crab-it's in season now," counseled Kathryn Loring to her sister before she and her husband made their first trip from Chicago to Florida in February of 1960. Once in Florida, Loring and her husband took her sister's advice, embarking on a self-proclaimed "sea food binge" that included devouring mullet, pompano, New England and Manhattan-style clam chowder, red snapper, shrimp, and, of course, stone crab. They found the "sweet and delectable" claws of stone crab at Hudgins Cafe in West Palm Beach, Florida, where surrounded by other sun-burned tourists they consumed the meat of a crab that …


Impact Of Increasing Nitrogen Fertilizer Rates Upon An Irrigated Tanzania Grass Pasture. 1. Dry Matter Yield, F. Queiroz-Neto, G. B. Martha Jr., M. A. Penati, M. Corsi, M. J. T. Menezes Sep 2021

Impact Of Increasing Nitrogen Fertilizer Rates Upon An Irrigated Tanzania Grass Pasture. 1. Dry Matter Yield, F. Queiroz-Neto, G. B. Martha Jr., M. A. Penati, M. Corsi, M. J. T. Menezes

IGC Proceedings (1977-2023)

An experiment was carried out with irrigated Tanzania grass (Panicum maximum, Jacq.) pasture receiving five nitrogen (N) rates of (0, 30, 60, 90 and 120 kg N ha-¹ cut-¹) during the growing season. N application increased dry matter yield and Tanzania growth rate linearly (P < 0.05). Responses to nitrogen applications were higher in the first two cuts of the growing season than in the last two cuts. The N fertilizer conversion into herbage dry matter was also higher in the beginning of the growing season.


Short-Term Study On 13Carbon Discrimination On Irrigated Tropical Pasture, G. B. Martha Jr., M. Corsi, P. C. O. Trivelin, F. Queiroz-Neto Sep 2021

Short-Term Study On 13Carbon Discrimination On Irrigated Tropical Pasture, G. B. Martha Jr., M. Corsi, P. C. O. Trivelin, F. Queiroz-Neto

IGC Proceedings (1977-2023)

A better understanding of pasture ecosystem can be obtained through the use of 13C discrimination technique. In this context, an experiment, assigned in a randomized complete block design with four replicates, was conducted to evaluate the Δ 13C (‰) discrimination, nitrogen (N) yield (kg N ha-¹), total nitrogen content (g kg dry matter (DM)-¹) and dry matter yield (kg DM ha-¹) on an irrigated Tanzania grass pasture (Panicum maximum, Jacq.) receiving increasing rates (0, 30, 60, 90 and 120 kg N ha-¹ cut-¹) of N fertilizer during the summer. Dry matter yield, N yield and nitrogen …


Apparent Recovery Of Surface Applied Nitrogen Fertilizer By A Coastcross Pasture, A. C. Primavesi, O. Primavesi, L. A. Corrêa, H. Cantarella, A. G. Silva Sep 2021

Apparent Recovery Of Surface Applied Nitrogen Fertilizer By A Coastcross Pasture, A. C. Primavesi, O. Primavesi, L. A. Corrêa, H. Cantarella, A. G. Silva

IGC Proceedings (1977-2023)

Nitrogen recoveries from five levels of urea and ammonium nitrate surface-applied on coastcross pasture, grown on a dark red latosol (Hapludox), in São Carlos, SP, Brazil, under tropical altitude climate, were estimated. Significant differences occurred within periods (P < 0.05), depending on climatic conditions. Under adequate plant growth conditions, mean N recovery from urea was about 67%, sometimes reaching 80%, of that from ammonium nitrate. Recovery of ammonium nitrate varied from 45 to 68% of applied N.


Soil Ph Correction Affecting N-Use Efficiency Of Urea By Brachiaria Brizantha Cv. Marandu Pastures, P. P. A. Oliveira, P. C. O. Trivelin, W. S. Oliveira, G. M. Teixeira, M. Corsi Sep 2021

Soil Ph Correction Affecting N-Use Efficiency Of Urea By Brachiaria Brizantha Cv. Marandu Pastures, P. P. A. Oliveira, P. C. O. Trivelin, W. S. Oliveira, G. M. Teixeira, M. Corsi

IGC Proceedings (1977-2023)

Nitrogen fertilization is one of the largest investment when recovering and intensifying pasture management. Urea nitrogen use efficiency was studied in Brachiaria brizantha pasture under tropical conditions where liming was applied to the soil in two dates ("early" and "late" - March and August, respectively). Lime was broadcasted and urea was either broadcasted or subsurface-band applied. "Early" applied lime caused 16,4% increase in forage dry matter yield in the rainy season. Urea-N recovered in the shoots was higher when subsurface band applied independently from time of lime application.


Development Of Scientific Concepts "Quality", "Quality Of Education", "Quality Management Of Education", Dilnavoz Makhametova Senior Teacher Sep 2021

Development Of Scientific Concepts "Quality", "Quality Of Education", "Quality Management Of Education", Dilnavoz Makhametova Senior Teacher

Central Asian Journal of Education

The article is devoted to the study of the problems of quality management in higher education. The author develops an integrated approach to understanding and measuring the quality of the educational process. The article clarifies and systematizes various approaches to assessing the main directions of quality management of educational services to ensure competitiveness in the field of higher education in Russia.


Pedagogical Innovation Education Cluster In The Development Of Natural Science Literacy: The Chirchik Experience Is In Practice., Nodira Abdukhamidovna Mirzaeva Phd, Abdukhamid Sattarovich Umarov Associate Professor Sep 2021

Pedagogical Innovation Education Cluster In The Development Of Natural Science Literacy: The Chirchik Experience Is In Practice., Nodira Abdukhamidovna Mirzaeva Phd, Abdukhamid Sattarovich Umarov Associate Professor

Central Asian Journal of Education

The article is being implemented by Chirchik State Pedagogical Institute as a new innovative approach that ensures continuity, consistency and consistency between the types of education in the field of Education. On the example of Chirchik experience, the cooperation between secondary schools, academic lyceums and Higher Education on the basis of the school laboratory and innovation pedagogical education cluster is presented as a practical basis for increasing the effectiveness of Education.


Bacterial Biofilm Growth On Various Dental Stabilization Systems For Avulsed And Luxated Teeth, Mahmoud Mona, Clay Walker, Luciana M. Shaddox, Roberta Pileggi Sep 2021

Bacterial Biofilm Growth On Various Dental Stabilization Systems For Avulsed And Luxated Teeth, Mahmoud Mona, Clay Walker, Luciana M. Shaddox, Roberta Pileggi

Oral Health Practice Faculty Publications

With the increased incidence of traumatic injuries and the advanced understanding of the periodontal and alveolar healing process, teeth splinting has become a common practice for stabilizing traumatized teeth. Consequently, several splinting materials and techniques have been introduced in the past few years. Despite the detrimental role of bacterial biofilm on healing, the level of biofilm development on these material surfaces has not been well investigated. Bacterial biofilms are severely detrimental for periodontal healing of avulsed and luxated teeth. Thus, biofilm growth becomes a critical factor in selecting the material of choice for dental splints. In this study, we aim …


The Stress-Active Cell Division Protein Zape Alters Ftsz Filament Architecture To Facilitate Division In Escherichia Coli, Eric C. Dibiasio, Rebecca A. Dickinson, Catherine E. Trebino, Colby N. Ferreira, Josiah J. Morrison, Jodi L. Camberg Sep 2021

The Stress-Active Cell Division Protein Zape Alters Ftsz Filament Architecture To Facilitate Division In Escherichia Coli, Eric C. Dibiasio, Rebecca A. Dickinson, Catherine E. Trebino, Colby N. Ferreira, Josiah J. Morrison, Jodi L. Camberg

Cell and Molecular Biology Faculty Publications

During pathogenic infections, bacterial cells experience environmental stress conditions, including low oxygen and thermal stress. Bacterial cells proliferate during infection and divide by a mechanism characterized by the assembly of a large cytoskeletal structure at the division site called the Z-ring. The major protein constituting the Z-ring is FtsZ, a tubulin homolog and GTPase that utilizes the nucleotide to assemble into dynamic polymers. In Escherichia coli, many cell division proteins interact with FtsZ and modulate Z-ring assembly, while others direct cell wall insertion and peptidoglycan remodeling. Here, we show that ZapE, an ATPase that accumulates during late constriction, directly interacts …


Advising Tip: Find The Barr And Free Help With Introductory Biology In Irvine 126, Ohio University College Of Arts & Sciences Sep 2021

Advising Tip: Find The Barr And Free Help With Introductory Biology In Irvine 126, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.


A Reversal In Hair Cell Orientation Organizes Both The Auditory And Vestibular Organs., Basile Tarchini Sep 2021

A Reversal In Hair Cell Orientation Organizes Both The Auditory And Vestibular Organs., Basile Tarchini

Faculty Research 2021

Sensory hair cells detect mechanical stimuli with their hair bundle, an asymmetrical brush of actin-based membrane protrusions, or stereocilia. At the single cell level, stereocilia are organized in rows of graded heights that confer the hair bundle with intrinsic directional sensitivity. At the organ level, each hair cell is precisely oriented so that its intrinsic directional sensitivity matches the direction of mechanical stimuli reaching the sensory epithelium. Coordinated orientation among neighboring hair cells usually ensures the delivery of a coherent local group response. Accordingly, hair cell orientation is locally uniform in the auditory and vestibular cristae epithelia in birds and …


Metabolomics Of Healthy And Stony Coral Tissue Loss Disease Affected Montastraea Cavernosa Corals, Jessica M. Deutsch, Olakunle A. Jaiyesimi, Kelly A. Pitts, Jay Houk, Blake Ushijima, Brian K. Walker, Valerie J. Paul, Neha Garg Sep 2021

Metabolomics Of Healthy And Stony Coral Tissue Loss Disease Affected Montastraea Cavernosa Corals, Jessica M. Deutsch, Olakunle A. Jaiyesimi, Kelly A. Pitts, Jay Houk, Blake Ushijima, Brian K. Walker, Valerie J. Paul, Neha Garg

Marine & Environmental Sciences Faculty Articles

Stony coral tissue loss disease, first observed in Florida in 2014, has now spread along the entire Florida Reef Tract and on reefs in many Caribbean countries. The disease affects a variety of coral species with differential outcomes, and in many instances results in whole-colony mortality. We employed untargeted metabolomic profiling of Montastraea cavernosa corals affected by stony coral tissue loss disease to identify metabolic markers of disease. Herein, extracts from apparently healthy, diseased, and recovered Montastraea cavernosa collected at a reef site near Ft. Lauderdale, Florida were subjected to liquid-chromatography mass spectrometry-based metabolomics. Unsupervised principal component analysis reveals wide …


Dynamic Changes Of Brain Cilia Transcriptomes Across The Human Lifespan, Siwei Chen, Wedad Alhassen, Roudabeh Vakil Monfared, Benjamin Vachirakorntong, Surya M. Nauli, Pierre Baldi, Amal Alachkar Sep 2021

Dynamic Changes Of Brain Cilia Transcriptomes Across The Human Lifespan, Siwei Chen, Wedad Alhassen, Roudabeh Vakil Monfared, Benjamin Vachirakorntong, Surya M. Nauli, Pierre Baldi, Amal Alachkar

Pharmacy Faculty Articles and Research

Almost all brain cells contain primary cilia, antennae-like microtubule sensory organelles, on their surface, which play critical roles in brain functions. During neurodevelopmental stages, cilia are essential for brain formation and maturation. In the adult brain, cilia play vital roles as signaling hubs that receive and transduce various signals and regulate cell-to-cell communications. These distinct roles suggest that cilia functions, and probably structures, change throughout the human lifespan. To further understand the age-dependent changes in cilia roles, we identified and analyzed age-dependent patterns of expression of cilia’s structural and functional components across the human lifespan. We acquired cilia transcriptomic data …


All-Women Drum Major Team Leads 2021 Uab Marching Blazers, Shannon Thomason Sep 2021

All-Women Drum Major Team Leads 2021 Uab Marching Blazers, Shannon Thomason

Browse All News

No abstract provided.


The Crossroads Of Glycoscience, Infection, And Immunology, Tanya R. Mckitrick, Margaret E. Ackerman, Robert M. Anthony, Clay S. Bennett, Michael Demetriou, Gregory A. Hudalla, Katharina Ribbeck, Stefan Ruhl, Christina M. Woo, Loretta Yang, Seth J. Zost, Ronald L. Schnaar, Tamara L. Doering Sep 2021

The Crossroads Of Glycoscience, Infection, And Immunology, Tanya R. Mckitrick, Margaret E. Ackerman, Robert M. Anthony, Clay S. Bennett, Michael Demetriou, Gregory A. Hudalla, Katharina Ribbeck, Stefan Ruhl, Christina M. Woo, Loretta Yang, Seth J. Zost, Ronald L. Schnaar, Tamara L. Doering

Dartmouth Scholarship

Advances in experimental capabilities in the glycosciences offer expanding opportunities for discovery in the broad areas of immunology and microbiology. These two disciplines overlap when microbial infection stimulates host immune responses and glycan structures are central in the processes that occur during all such encounters. Microbial glycans mediate host-pathogen interactions by acting as surface receptors or ligands, functioning as virulence factors, impeding host immune responses, or playing other roles in the struggle between host and microbe. In the context of the host, glycosylation drives cell–cell interactions that initiate and regulate the host response and modulates the effects of antibodies and …


"It Was A Season..." Postpartum Depression In American Indian/Alaska Native Women, Jennifer Leigh Heck Sep 2021

"It Was A Season..." Postpartum Depression In American Indian/Alaska Native Women, Jennifer Leigh Heck

Dissertations

Postpartum depression (PPD) is linked to diminished maternal, pediatric, and family health outcomes and is designated as the most common childbirth complication. PPD is found in most populations, and touts international status as a major public health concern. Clinicians define PPD as an episode of major depressive disorder with a "peripartum onset" that occurs within the first year after delivery. Studies suggest that American Indian/Alaska Native (AI/AN) women suffer higher PPD prevalence (14% to 29%) than other United States' women, revealing a racial/ethnic disparity. Health disparities research is a national public health priority and substantiates the need to explore PPD …


Crow's Nest, September 27, 2021, Crow's Nest Staff Sep 2021

Crow's Nest, September 27, 2021, Crow's Nest Staff

Crow's Nest

The September 27, 2021, issue of the Crow's Nest.


Atomistic Simulations And In Silico Mutational Profiling Of Protein Stability And Binding In The Sars-Cov-2 Spike Protein Complexes With Nanobodies: Molecular Determinants Of Mutational Escape Mechanisms, Gennady M. Verkhivker, Steve Agajanian, Deniz Yasar Oztas, Grace Gupta Sep 2021

Atomistic Simulations And In Silico Mutational Profiling Of Protein Stability And Binding In The Sars-Cov-2 Spike Protein Complexes With Nanobodies: Molecular Determinants Of Mutational Escape Mechanisms, Gennady M. Verkhivker, Steve Agajanian, Deniz Yasar Oztas, Grace Gupta

Mathematics, Physics, and Computer Science Faculty Articles and Research

Structure-functional studies have recently revealed a spectrum of diverse high-affinity nanobodies with efficient neutralizing capacity against SARS-CoV-2 virus and resilience against mutational escape. In this study, we combine atomistic simulations with the ensemble-based mutational profiling of binding for the SARS-CoV-2 S-RBD complexes with a wide range of nanobodies to identify dynamic and binding affinity fingerprints and characterize the energetic determinants of nanobody-escaping mutations. Using an in silico mutational profiling approach for probing the protein stability and binding, we examine dynamics and energetics of the SARS-CoV-2 complexes with single nanobodies Nb6 and Nb20, VHH E, a pair combination VHH E + …


Editorial: Unraveling Mechanisms Underlying Annual Plankton Blooms In The North Atlantic And Their Implications For Biogenic Aerosol Properties And Cloud Formation, Michael Behrenfeld, Sarah D. Brooks, Peter Gaube, Kristina D.A. Mojica Sep 2021

Editorial: Unraveling Mechanisms Underlying Annual Plankton Blooms In The North Atlantic And Their Implications For Biogenic Aerosol Properties And Cloud Formation, Michael Behrenfeld, Sarah D. Brooks, Peter Gaube, Kristina D.A. Mojica

Faculty Publications

No abstract provided.


Tb3+-Atorvastatin Doped In Poly(Ethylene Glycol) Optical Biosensor For Selective Determination Of Progesterone And Testosterone In Serum Samples, Ekram Hany Mohamed, Mohamed S. S. Attia, Safwat A. Mahmoud,, Amal M. Ahmed,, Tarek A. Amin, Ahmed O. Youssef, Mona N. Abou-Omar,, Mohammed A. C Amin, Sep 2021

Tb3+-Atorvastatin Doped In Poly(Ethylene Glycol) Optical Biosensor For Selective Determination Of Progesterone And Testosterone In Serum Samples, Ekram Hany Mohamed, Mohamed S. S. Attia, Safwat A. Mahmoud,, Amal M. Ahmed,, Tarek A. Amin, Ahmed O. Youssef, Mona N. Abou-Omar,, Mohammed A. C Amin,

Pharmacy

An innovative, simple and cost effective Tb3+-atorvastatin photo probe was designed and used as a core for a spectrofluorometric approach to sensitively determine two vital biological compounds in serum samples. Tb3+-atorvastatin complex displays a characteristic electrical band with λem at 545 nm with significant luminescence intensity, which is quenched in the presence of progesterone and testosterone at two variant sets of pH; 6.2 and 7.5, respectively. The conditions were optimized and the best solvent for operation was found to be acetonitrile with λex at 320 nm. Progesterone and testosterone were assessed in serum samples using the same optimal conditions within …


Down Syndrome And Dementia:: A Patient And Care-Giver Centered Approach, Mary M. Stephens, E. Adel Herge, Charmaine Wright Sep 2021

Down Syndrome And Dementia:: A Patient And Care-Giver Centered Approach, Mary M. Stephens, E. Adel Herge, Charmaine Wright

Department of Occupational Therapy Faculty Papers

No abstract provided.


Microrna Isoforms Contribution To Melanoma Pathogenesis, Elisabetta Broseghini, Emi Dika, Eric Londin, Manuela Ferracin Sep 2021

Microrna Isoforms Contribution To Melanoma Pathogenesis, Elisabetta Broseghini, Emi Dika, Eric Londin, Manuela Ferracin

Computational Medicine Center Faculty Papers

Cutaneous melanoma (CM) is the most lethal tumor among skin cancers, and its incidence is constantly increasing. A deeper understanding of the molecular processes guiding melanoma pathogenesis could improve diagnosis, treatment and prognosis. MicroRNAs play a key role in melanoma biology. Recently, next generation sequencing (NGS) experiments, designed to assess small-RNA expression, revealed the existence of microRNA variants with different length and sequence. These microRNA isoforms are known as isomiRs and provide an additional layer to the complex non-coding RNA world. Here, we collected data from NGS experiments to provide a comprehensive characterization of miRNA and isomiR dysregulation in benign …


Development Of A Genomic Prediction Pipeline For Maintaining Comparable Sample Sizes In Training And Testing Sets Across Prediction Schemes Accounting For The Genotype-By-Environment Interaction, Reyna Persa, Martin Grondona, Diego Jarquin Sep 2021

Development Of A Genomic Prediction Pipeline For Maintaining Comparable Sample Sizes In Training And Testing Sets Across Prediction Schemes Accounting For The Genotype-By-Environment Interaction, Reyna Persa, Martin Grondona, Diego Jarquin

Department of Agronomy and Horticulture: Faculty Publications

The global growing population is experiencing challenges to satisfy the food chain supply in a world that faces rapid changes in environmental conditions complicating the development of stable cultivars. Emergent methodologies aided by molecular marker information such as marker assisted selection (MAS) and genomic selection (GS) have been widely adopted to assist the development of improved genotypes. In general, the implementation of GS is not straightforward, and it usually requires cross-validation studies to find the optimum set of factors (training set sizes, number of markers, quality control, etc.) to use in real breeding applications. In most cases, these different scenarios …


Chimes: September 27, 2021, Calvin University Sep 2021

Chimes: September 27, 2021, Calvin University

Chimes

Ready for dorm life by Timothy Lin

West Michigan orgs are leading efforts to resettle Afghan refugees. You can help. by Grace Toma

German, Dutch students adapt to finish degrees after program cuts by Katherine Benedict

More fans, more fun: Athletics event restrictions lighten up for the fall by Jamison Van Andel

Mind the gap: How students made the most out of their time off school in 2020 by Hadassa Ribeiro

If you're calling yourself pro-life, you need to become involved in the foster care system by Savannah Shustack