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2021

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Wildlife Responses To Livestock Guard Dogs And Domestic Sheep On Open Range, Daniel Kinka, Jeffrey T. Schultz, Julie K. Young Nov 2021

Wildlife Responses To Livestock Guard Dogs And Domestic Sheep On Open Range, Daniel Kinka, Jeffrey T. Schultz, Julie K. Young

United States Department of Agriculture Wildlife Services: Staff Publications

Domestic sheep (Ovis aries) are an attractant to carnivores; however, sheep are often accompanied by humans and livestock guardian dogs (LGDs; Canis familiaris), which defend sheep from depredation. Sheep also compete directly with wildlife for grazing resources. Although practiced for millennia in much of the world outside North America, the effect that transhumance has on wildlife is poorly understood. To test the effect of sheep bands (sheep, humans, and LGDs) on wildlife, we modeled the detection probability of wild mammals relative to the presence of sheep bands in the Northwestern United States. Sheep band presence was associated …


Mongooses (Urva Auropunctata) As Reservoir Hosts Of Leptospira Species In The United States Virgin Islands, 2019–2020, Hannah M. Cranford, A. Springer Browne, Karen Lecount, Tammy Anderson, Camila Hamond, Linda Schlater, Tod Stuber, Valicia J. Burke-France, Marissa Taylor, Cosme J. Harrison, Katia Y. Matias, Alexandra Medley, John Rossow, Nicholas Wiese, Leanne Jankelunas, Leah De Wilde, Michelle Mehalick, Gerard L. Blanchard, Keith R. Garcia, Alan S. Mckinley, Claudia D. Lombard, Nicole F. Angeli, David Horner, Thomas Kelley, David J. Worthington, Jennifer Valiulis, Bethany Bradford, Are Berentsen, Johanna S. Salzer, Renee Galloway, Ilana J. Schafer, Kristine Bisgard, Joseph Roth, Brett R. Ellis, Esther M. Ellis, Jarlath E. Nally Nov 2021

Mongooses (Urva Auropunctata) As Reservoir Hosts Of Leptospira Species In The United States Virgin Islands, 2019–2020, Hannah M. Cranford, A. Springer Browne, Karen Lecount, Tammy Anderson, Camila Hamond, Linda Schlater, Tod Stuber, Valicia J. Burke-France, Marissa Taylor, Cosme J. Harrison, Katia Y. Matias, Alexandra Medley, John Rossow, Nicholas Wiese, Leanne Jankelunas, Leah De Wilde, Michelle Mehalick, Gerard L. Blanchard, Keith R. Garcia, Alan S. Mckinley, Claudia D. Lombard, Nicole F. Angeli, David Horner, Thomas Kelley, David J. Worthington, Jennifer Valiulis, Bethany Bradford, Are Berentsen, Johanna S. Salzer, Renee Galloway, Ilana J. Schafer, Kristine Bisgard, Joseph Roth, Brett R. Ellis, Esther M. Ellis, Jarlath E. Nally

United States Department of Agriculture Wildlife Services: Staff Publications

During 2019–2020, the Virgin Islands Department of Health investigated potential animal reservoirs of Leptospira spp., the bacteria that cause leptospirosis. In this cross-sectional study, we investigated Leptospira spp. exposure and carriage in the small Indian mongoose (Urva auropunctata, syn: Herpestes auropunctatus), an invasive animal species. This study was conducted across the three main islands of the U.S. Virgin Islands (USVI), which are St. Croix, St. Thomas, and St. John. We used the microscopic agglutination test (MAT), fluorescent antibody test (FAT), real-time polymerase chain reaction (lipl32 rt-PCR), and bacterial culture to evaluate serum and kidney specimens and compared the …


Quality Of Life Assessment Among Patients Suffering From Different Dermatological Diseases, Hend M. Alotaibi, Nuha A. Alfurayh, Bayan M. Alnooh, Nouf A. Aljomah, Sadeem M. Alqahtani Nov 2021

Quality Of Life Assessment Among Patients Suffering From Different Dermatological Diseases, Hend M. Alotaibi, Nuha A. Alfurayh, Bayan M. Alnooh, Nouf A. Aljomah, Sadeem M. Alqahtani

Saudi Medical Journal

Objectives: To assess the quality of life (QoL) of patients with different dermatological diseases. Multiple international studies have evaluated the QoL among patients with different dermatological diseases; however, few studies of this kind have been conducted in Saudi Arabia. Methods: This quantitative, observational, cross-sectional study was carried out in the dermatology outpatient clinics of King Saud University Medical City, Riyadh, Saudi Arabia, from September 2019 until February 2020. Data was collected using the validated Arabic version of the Dermatology of Life Quality Index (DLQI). Results: A total of 391 patients ≥18 years participated in the study. The mean age of …


Synonymous And Non-Synonymous Polymorphisms In Toll-Like Receptor 2 (Tlr2) Gene Among Complicated Measles Cases At A Tertiary Care Hospital, Peshawar, Pakistan, Muhammad Ilyas, Sumera Afzal, Saad Alghamdi, Muhammad Khurram Nov 2021

Synonymous And Non-Synonymous Polymorphisms In Toll-Like Receptor 2 (Tlr2) Gene Among Complicated Measles Cases At A Tertiary Care Hospital, Peshawar, Pakistan, Muhammad Ilyas, Sumera Afzal, Saad Alghamdi, Muhammad Khurram

Saudi Medical Journal

Objectives: To detect single nucleotide polymorphism in toll-like receptor 2 (TLR2) gene in complicated cases of measles, in order to understand the genetic basis of complex human immune responses against measles complications. Methods: A total of 100 children consisted of 50 measles complicated cases while rest were gender matched disease-free individuals who served as controls for this study. Patient demographic data and clinical information were recorded on a separate pre-designed model form. All exonic regions of TLR2 gene of the patients and control samples were amplified through polymerase chain reaction. Various in-silico mutation verification tools like protein variation effect analyzer, …


Qupath Digital Immunohistochemical Analysis Of Placental Tissue, Ashley L. Hein, Maheswari Mukherjee, Geoffrey A. Talmon, Sathish Kumar Natarajan, Tara M. Nordgren, Elizabeth Lyden, Corrine K. Hanson, Jesse L. Cox, Annelisse Santiago‑Pintado, Mariam A. Molani, Matthew Van Ormer, Maranda Thompson, Melissa K. Thoene, Aunum Akhter, Ann Anderson‑Berry, Ana G. Yuil-Valdes Nov 2021

Qupath Digital Immunohistochemical Analysis Of Placental Tissue, Ashley L. Hein, Maheswari Mukherjee, Geoffrey A. Talmon, Sathish Kumar Natarajan, Tara M. Nordgren, Elizabeth Lyden, Corrine K. Hanson, Jesse L. Cox, Annelisse Santiago‑Pintado, Mariam A. Molani, Matthew Van Ormer, Maranda Thompson, Melissa K. Thoene, Aunum Akhter, Ann Anderson‑Berry, Ana G. Yuil-Valdes

Department of Nutrition and Health Sciences: Faculty Publications

Background: QuPath is an open‑source digital image analyzer notable for its user‑friendly design, cross‑platform compatibility, and customizable functionality. Since it was first released in 2016, at least 624 publications have reported its use, and it has been applied in a wide spectrum of settings. However, there are currently limited reports of its use in placental tissue. Here, we present the use of QuPath to quantify staining of G‑protein coupled receptor 18 (GPR18), the receptor for the pro‑resolving lipid mediator Resolvin D2, in placental tissue. Methods: Whole slide images of vascular smooth muscle (VSM) and extravillous trophoblast (EVT) cells stained …


Low Light Intensity Delays Vegetative Phase Change, Mingli Xu, Tieqiang Hu, R Scott Poethig Nov 2021

Low Light Intensity Delays Vegetative Phase Change, Mingli Xu, Tieqiang Hu, R Scott Poethig

Faculty Publications

Plants that develop under low light (LL) intensity often display a phenotype known as the “shade tolerance syndrome (STS)”. This syndrome is similar to the phenotype of plants in the juvenile phase of shoot development, but the basis for this similarity is unknown. We tested the hypothesis that the STS is regulated by the same mechanism that regulates the juvenile vegetative phase by examining the effect of LL on rosette development in Arabidopsis (Arabidopsis thaliana). We found that LL prolonged the juvenile vegetative phase and that this was associated with an increase in the expression of the master …


Effects Of Sesame Consumption On Inflammatory Biomarkers In Humans: A Systematic Review And Meta-Analysis Of Randomized Controlled Trials, Shabnam Rafiee, Roghaye Faryabi, Mohammad Ali Zareian, Jessie Hawkins, Nitin Shivappa Mbbs, Mph, Ph.D., Laila Shirbeigi Nov 2021

Effects Of Sesame Consumption On Inflammatory Biomarkers In Humans: A Systematic Review And Meta-Analysis Of Randomized Controlled Trials, Shabnam Rafiee, Roghaye Faryabi, Mohammad Ali Zareian, Jessie Hawkins, Nitin Shivappa Mbbs, Mph, Ph.D., Laila Shirbeigi

Faculty Publications

Objectives. Existing evidence produces conflicting findings regarding the effect of sesame intake on inflammatory biomarkers; thisknowledge gap has yet to be met through systematic review and meta-analysis. )is meta-analysis of randomized, controlledclinical trials (RCTs) was conducted to evaluate the effects of sesame consumption on markers of inflammation in humans. Methods. PubMed, Scopus, and the Cochrane Database of Systematic Reviews were searched through August 2020 to identify relevant papers for inclusion. Using the random-effects model, data were evaluated as weighted mean differences (WMD) with 95% confidence intervals (CI). Cochrane’s Q and I-squared (I2) tests were used to …


Soil Hydrologic Grouping Guide Which Soil And Weather Properties Best Estimate Corn Nitrogen Need, Gregory Mac Bean, Curtis J. Ransom, Newell R. Kitchen, Peter C. Scharf, Kristen S. Veum, James J. Camberato, Richard B. Ferguson, Fabián G. Fernández, David W. Franzen, Carrie A.M. Laboski, Emerson D. Nafziger, John E. Sawyer, Robert L. Nielsen Nov 2021

Soil Hydrologic Grouping Guide Which Soil And Weather Properties Best Estimate Corn Nitrogen Need, Gregory Mac Bean, Curtis J. Ransom, Newell R. Kitchen, Peter C. Scharf, Kristen S. Veum, James J. Camberato, Richard B. Ferguson, Fabián G. Fernández, David W. Franzen, Carrie A.M. Laboski, Emerson D. Nafziger, John E. Sawyer, Robert L. Nielsen

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Nitrogen fertilizer recommendations in corn (Zea mays L.) that match the economically optimal nitrogen fertilizer rate (EONR) are imperative for profitability and minimizing environmental degradation. However, the amount of soil N available for the crop depends on soil and weather factors, making it difficult to know the EONR from year-to-year and from field-to-field. Our objective was to explore, within the framework of hydrologic soil groups and drainage classifications (HGDC), which site-specific soil and weather properties best estimated corn N needs (i.e., EONR) for two application timings (at-planting and side-dress). Included in this investigation was a validation step using an independent …


Molecular Mechanisms Underlying Enhanced Hemichannel Function Of A Cataract-Associated Cx50 Mutant, Jun-Jie Tong, Umair Khan, Bassam George Haddad, Peter J. Minogue, Eric C. Beyer, Vivian M. Berthoud, Steve L. Reichow, Lisa Ebihra Nov 2021

Molecular Mechanisms Underlying Enhanced Hemichannel Function Of A Cataract-Associated Cx50 Mutant, Jun-Jie Tong, Umair Khan, Bassam George Haddad, Peter J. Minogue, Eric C. Beyer, Vivian M. Berthoud, Steve L. Reichow, Lisa Ebihra

Chemistry Faculty Publications and Presentations

Connexin-50 (Cx50) is among the most frequently mutated genes associated with congenital cataracts. Although most of these disease-linked variants cause loss of function because of misfolding or aberrant trafficking, others directly alter channel properties. The mechanistic bases for such functional defects are mostly unknown. We investigated the functional and structural properties of a cataract-linked mutant, Cx50T39R (T39R), in the Xenopus oocyte system. T39R exhibited greatly enhanced hemichannel currents with altered voltage-gating properties compared to Cx50 and induced cell death. Coexpression of mutant T39R with wild-type Cx50 (to mimic the heterozygous state) resulted in hemichannel currents whose properties were indistinguishable from …


Do Firms Respond To Peer Disclosures? Evidence From Clinical Trial Disclosures, Vedran Capkun, Yun Lou, Clemens A. Otto, Yin Wang Nov 2021

Do Firms Respond To Peer Disclosures? Evidence From Clinical Trial Disclosures, Vedran Capkun, Yun Lou, Clemens A. Otto, Yin Wang

Research Collection School Of Accountancy

We examine whether a firm’s decision to disclose non-financial proprietary information depends on peer disclosures of similar information. Using a sample of 5,035 unique clinical trials by U.S. pharmaceutical firms over the 2007-2014 period, we find that the firm is less likely to disclose its own clinical trial results if peers have published clinical trial results pertaining to the same medical condition. Conditional on disclosing clinical trial results, the firm is also less likely to disclose the trial results on time when peers have disclosed their clinical trial results. Our cross-sectional tests suggest that proprietary costs of disclosure play an …


N Y State Dent J November 2021 Nov 2021

N Y State Dent J November 2021

The New York State Dental Journal

The New York State Dental Journal (NYSDJ) is produced by the New York State Dental Association (NYSDA) six times a year, in January, March, April, July, September and November. Each issue features clinical and scientific articles written by researchers and practitioners from around the globe and is subject to review by a panel of specialists convened by the Editor.

Issues include cover and feature articles alongside regular columns with regional news impacting the New York membership including editorial and perspectives columns, legal, association activities, component news, continuing education opportunities, and classifieds.


Neurotoxicological Effects Of Chlorpyrifos And Deltamethrin On Dopamine And Acetylcholine Systems In Drosophila Melanogaster, Hala Husam Abdul Baki Nov 2021

Neurotoxicological Effects Of Chlorpyrifos And Deltamethrin On Dopamine And Acetylcholine Systems In Drosophila Melanogaster, Hala Husam Abdul Baki

Theses

Emerging evidence suggests a positive association between pesticide exposure and sporadic Parkinson's disease (PD) development. The molecular mechanisms of PD and other neurodegenerative diseases are not fully understood, which hinders the development of therapeutic agents to cure or prevent the development of such diseases. Drosophila has been widely used as a model organism to study various neurodegenerative diseases and to screen for promising therapeutic agents. The aims of this study were: (i) investigating the toxic effect of 24 hours exposure to chlorpyrifos (CPF) and deltamethrin (DLM) on the dopaminergic system and AChE activity in Drosophila melanogaster; (ii) comparing different methodologies …


The Effect Of Natural Elicitors And Cold Storage Period On Quality Improvement Of Uae Date Palm Fruits (Phoenix Dactylifera, Cv. Barhi), Fatima Yaaqoub Yousef Al Shaibani Nov 2021

The Effect Of Natural Elicitors And Cold Storage Period On Quality Improvement Of Uae Date Palm Fruits (Phoenix Dactylifera, Cv. Barhi), Fatima Yaaqoub Yousef Al Shaibani

Theses

Date palm is an agricultural crop of economic importance in most Arab countries. Among the different varieties of date palms grown in the United Arab Emirates, the Barhi variety is extremely popular and is often consumed at the bisr stage (first edible stage). However, the major challenge for this fruit at bisr stage is to maintain its quality over a long period after harvest and during marketing. The objective of this study was to evaluate the synergistic effect of preharvest spraying with a natural elicitor, namely chitosan (Ch) 1%, alone and in combination with salicylic acid (SA) 2 mM and …


Comparison Of Three Different Woody Plant Species For Their Ability To Utilize Nutritional Elements Supplied In The Form Of Biosolids And Mineral Fertilizers, Fatima El-Telib Hassan Nov 2021

Comparison Of Three Different Woody Plant Species For Their Ability To Utilize Nutritional Elements Supplied In The Form Of Biosolids And Mineral Fertilizers, Fatima El-Telib Hassan

Theses

Crop production systems of the future will need to focus on recycling rather than flow- through of mineral nutrients. Much of the nutrients that leave agricultural systems with crop products eventually end up in household waste and sewage. Returning nutrientrich products from wastewater treatment to agricultural soils must be done in an environmentally sound and culturally acceptable manner. More than 300,000 hectares of forest have been planted in the United Arab Emirates (UAE), consisting mainly of native species, such as Prosopis cineraria (Ghāf) and Vachellia tortilis (Samr). It has been proposed that sewage sludge, the dry residue from wastewater treatment, …


Characterization Of The Lining Epithelium Of Normal And Precancerous Uterine Cervix In Mice, Reem Mamoun Shouk Nov 2021

Characterization Of The Lining Epithelium Of Normal And Precancerous Uterine Cervix In Mice, Reem Mamoun Shouk

Dissertations

Despite the fact that cervical cancer is a common health issue among women worldwide, little is known regarding the epithelial lining of the uterine cervix where cancer originates. Cancer development involves alterations in carbohydrate expression and changes in the dynamics of cellular proliferation and differentiation. Therefore, the aim of this study was to define carbohydrate moieties and cellular dynamics of the epithelial lining of the uterine cervix in normal mice and then in mice developing cervical precancerous lesions. Since the uterus undergoes cyclic changes, mice in each of the four stages of the estrus cycle were first identified using both …


Improving Phytoremediation Of Oil Polluted Soil In The Uae Using Acc Deaminase Producing Bacteria Under Arid Conditions, Maitha Mubarak Almansoori Nov 2021

Improving Phytoremediation Of Oil Polluted Soil In The Uae Using Acc Deaminase Producing Bacteria Under Arid Conditions, Maitha Mubarak Almansoori

Theses

Many 1-aminocyclopropane-1-carboxylic acid (ACC) deaminase-producing and oil-degrading rhizosphere actinobacteria were isolated from oil-contaminated soils in the United Arab Emirates. These actinobacterial isolates were further selected based on their ability to solubilize phosphorus, to produce siderophores, and to produce plant growth regulators (PGRs) including auxins and polyamines. The ability of the most-promising isolate #20 (Streptomyces sp.) to promote the growth of the hyper-accumulating plants “Bermuda grass” in soil polluted with Light Arabian Crude Oil (LACO) was evaluated under greenhouse conditions. Under controlled greenhouse conditions, the application of the strongest Streptomyces sp. #20 which exhibited the maximum production of ACC deaminase and …


Impact Of Date-Pit Activated Carbon In Different Applications: Biomedical And Environment, Betty Titus Mathew Nov 2021

Impact Of Date-Pit Activated Carbon In Different Applications: Biomedical And Environment, Betty Titus Mathew

Dissertations

Activated carbon (AC) or activated charcoal are black carbonaceous porous solid material with prominent physico-chemical properties such as low volume pore size distribution, high specific surface area, and high-degree of surface reactivity for adsorption and other chemicals reactions. AC as strong and reliable adsorbent have been reported to be employed in diverse applications stretching from water/air purification, medical, sewage treatment, energy storage devices, catalyst, supercapacitor electrodes fabrication, and as biosensors component. In this current work, AC was produced from date pits, which is a common biological waste product in UAE, and used for biomedical and environmental applications instead of using …


Effect Of Breathing Exercises On Perceived Stress Level Among The French-Speaking Community In Abu Dhabi, Uae: A Comparative Study Between Online And Mobile Application Delivery Methods, Nathalie El Asmar Nov 2021

Effect Of Breathing Exercises On Perceived Stress Level Among The French-Speaking Community In Abu Dhabi, Uae: A Comparative Study Between Online And Mobile Application Delivery Methods, Nathalie El Asmar

Theses

Breathing exercises have many health benefits, especially in terms of stress reduction. Several studies have examined the effect of breathing on stress levels; however, there is a lack of studies comparing delivery methods. This study aimed to compare the difference in perceived stress levels in people who performed breathing exercises face-to-face using an online video conferencing tool versus people who used a mobile breathing application. The sample consisted of sixty-two French-speaking individuals living in Abu Dhabi, United Arab Emirates. Before beginning the study, volunteers completed the Perceived Stress Scale-14 items. Those with results that showed a medium to a high …


Biological Treatment Of Produced Water Using Algae: A Proof Of Concept, Shibin Hashem Mohammed Nadersha Nov 2021

Biological Treatment Of Produced Water Using Algae: A Proof Of Concept, Shibin Hashem Mohammed Nadersha

Theses

Produced water (PW) is the effluent generated during oil mining and extraction. On average, for every barrel of oil, 4 - 5 barrels of PW are generated worldwide. In UAE, 1.22 billion cubic meters of PW were generated in the year 2017. Proper management of PW is thus very important taking into account the large volumes of it being generated. In addition, PW is considered toxic as it contains various contaminants such as aliphatic and aromatic hydrocarbons, inorganic salts, metals, phenols, radioactive materials, and chemical additives. Disposal of untreated PW into oceans and water bodies can cause adverse effects on …


Representation Learning On Multi-Layered Heterogeneous Network, Delvin Ce Zhang, Hady W. Lauw Nov 2021

Representation Learning On Multi-Layered Heterogeneous Network, Delvin Ce Zhang, Hady W. Lauw

Research Collection School Of Computing and Information Systems

Network data can often be represented in a multi-layered structure with rich semantics. One example is e-commerce data, containing user-user social network layer and item-item context layer, with cross-layer user-item interactions. Given the dual characters of homogeneity within each layer and heterogeneity across layers, we seek to learn node representations from such a multi-layered heterogeneous network while jointly preserving structural information and network semantics. In contrast, previous works on network embedding mainly focus on single-layered or homogeneous networks with one type of nodes and links. In this paper we propose intra- and cross-layer proximity concepts. Intra-layer proximity simulates propagation along …


Intercept Graph: An Interactive Radial Visualization For Comparison Of State Changes, Shaolun Ruan, Yong Wang, Qiang Guan Nov 2021

Intercept Graph: An Interactive Radial Visualization For Comparison Of State Changes, Shaolun Ruan, Yong Wang, Qiang Guan

Research Collection School Of Computing and Information Systems

State change comparison of multiple data items is often necessary in multiple application domains, such as medical science, financial engineering, sociology, biological science, etc. Slope graphs and grouped bar charts have been widely used to show a “before-and-after” story of different data states and indicate their changes. However, they visualize state changes as either slope or difference of bars, which has been proved less effective for quantitative comparison. Also, both visual designs suffer from visual clutter issues with an increasing number of data items. In this paper, we propose Intercept Graph, a novel visual design to facilitate effective interactive comparison …


Predicting Anti-Asian Hateful Users On Twitter During Covid-19, Jisun An, Haewoon Kwak, Claire Seungeun Lee, Bogang Jun, Yong-Yeol Ahn Nov 2021

Predicting Anti-Asian Hateful Users On Twitter During Covid-19, Jisun An, Haewoon Kwak, Claire Seungeun Lee, Bogang Jun, Yong-Yeol Ahn

Research Collection School Of Computing and Information Systems

We investigate predictors of anti-Asian hate among Twitter users throughout COVID-19. With the rise of xenophobia and polarization that has accompanied widespread social media usage in many nations, online hate has become a major social issue, attracting many researchers. Here, we apply natural language processing techniques to characterize social media users who began to post anti-Asian hate messages during COVID-19. We compare two user groups—those who posted anti-Asian slurs and those who did not—with respect to a rich set of features measured with data prior to COVID-19 and show that it is possible to predict who later publicly posted anti-Asian …


Contrastive Pre-Training Of Gnns On Heterogeneous Graphs, Xunqiang Jiang, Yuanfu Lu, Yuan Fang, Chuan Shi Nov 2021

Contrastive Pre-Training Of Gnns On Heterogeneous Graphs, Xunqiang Jiang, Yuanfu Lu, Yuan Fang, Chuan Shi

Research Collection School Of Computing and Information Systems

While graph neural networks (GNNs) emerge as the state-of-the-art representation learning methods on graphs, they often require a large amount of labeled data to achieve satisfactory performance, which is often expensive or unavailable. To relieve the label scarcity issue, some pre-training strategies have been devised for GNNs, to learn transferable knowledge from the universal structural properties of the graph. However, existing pre-training strategies are only designed for homogeneous graphs, in which each node and edge belongs to the same type. In contrast, a heterogeneous graph embodies rich semantics, as multiple types of nodes interact with each other via different kinds …


The "Silent Teacher": Learning By Teaching Via Writing A Verbatim Teaching Script, Kagen Y. L. Lim, Sarah Shi Hui Wong, Stephen Wee Hun Lim Nov 2021

The "Silent Teacher": Learning By Teaching Via Writing A Verbatim Teaching Script, Kagen Y. L. Lim, Sarah Shi Hui Wong, Stephen Wee Hun Lim

Research Collection School of Social Sciences

Learning by teaching others is a potent educational strategy, but its implementation is typically cumbersome. This study (N = 108) investigated “silent teaching”—writing a verbatim teaching script—as a convenient approach for independent learning, while assessing whether the teaching benefit is a production benefit. Learners studied a science text on the Doppler effect using one of three learning methods: (1) generating and studying their own notes (restudying control), (2) preparing to teach and then verbally teaching (verbal teaching), or (3) preparing to teach and then writing a verbatim teaching script (silent teaching). On a conceptual knowledge retention test 1 week later, …


Protein Deep Profile And Model Predictions For Identifying The Causal Genes Of Male Infertility Based On Deep Learning, Fang Xu, Ganggang Guo, Feida Zhu, Xiaojun Tan, Liqing Fan Nov 2021

Protein Deep Profile And Model Predictions For Identifying The Causal Genes Of Male Infertility Based On Deep Learning, Fang Xu, Ganggang Guo, Feida Zhu, Xiaojun Tan, Liqing Fan

Research Collection School Of Computing and Information Systems

A principal task in dissecting the genetics of complex traits is to identify causal genes for disease phenotypes. Millions of genes have been sequenced in data-driven genomics era, but their causal relationships with disease phenotypes remain limited, due to the difficulty of elucidating underlying causal genes by laboratory-based strategies. Here, we proposed an innovative deep learning computational modeling alternative (DPPCG framework) for identifying causal (coding) genes for a specific disease phenotype. In terms of male infertility, we introduced proteins as intermediate cell variables, leveraging integrated deep knowledge representations (Word2vec, ProtVec, Node2vec, and Space2vec) quantitatively represented as ‘protein deep profiles’. We …


Editorial: Fresh Faces, A New Look, And A Bright Future For Lajam, Miriam Marmontel, Daniel Gonzalez-Socoloske Nov 2021

Editorial: Fresh Faces, A New Look, And A Bright Future For Lajam, Miriam Marmontel, Daniel Gonzalez-Socoloske

Faculty Publications

No abstract provided.


Making A Water Data System Responsive To Information Needs Of Decision Makers, Alida Cantor, Michael Kiparsky, Susan S. Hubbard, Ronan Kennedy, Lidia Cano Pecharroman, Kamyar Guivetchi, Gary Darling, Christina Mccready, Roger Bales Nov 2021

Making A Water Data System Responsive To Information Needs Of Decision Makers, Alida Cantor, Michael Kiparsky, Susan S. Hubbard, Ronan Kennedy, Lidia Cano Pecharroman, Kamyar Guivetchi, Gary Darling, Christina Mccready, Roger Bales

Geography Faculty Publications and Presentations

Evidence-based environmental management requires data that are sufficient, accessible, useful and used. A mismatch between data, data systems, and data needs for decision making can result in inefficient and inequitable capital investments, resource allocations, environmental protection, hazard mitigation, and quality of life. In this paper, we examine the relationship between data and decision making in environmental management, with a focus on water management. We focus on the concept of decision-driven data systems—data systems that incorporate an assessment of decision-makers' data needs into their design. The aim of the research was to examine the process of translating data into effective …


Immobilization Of Lipase On Metal Organic Frameworks For Biodiesel Production, Reem L Husam Safwan Shoma Nov 2021

Immobilization Of Lipase On Metal Organic Frameworks For Biodiesel Production, Reem L Husam Safwan Shoma

Theses

For the economical application of enzymatic processes in biodiesel production, lipase enzyme has to be used in immobilized form to allow easy retention and reuse. The main challenges facing the industrialization of the enzymatic process are the high mass transfer resistance, the tendency to adsorb the by-product glycerol onto the support matrix and poor operational stability. These problems can be solved by a good selection of supports of favourable surface characteristics and pore sizes. In that regard, increasing interest has recently been in Metal-Organic Frameworks (MOFs) as a new kind of porous support for enzyme immobilization. Physical adsorption, which is …


Attenuated Bacteria Potentiate The Outcome Of Immunotherapy With Pd-L1 Blockade In A Pre-Clinical Model Of Colorectal Cancer, Besan Haytham Mohammad Al-Saafeen Nov 2021

Attenuated Bacteria Potentiate The Outcome Of Immunotherapy With Pd-L1 Blockade In A Pre-Clinical Model Of Colorectal Cancer, Besan Haytham Mohammad Al-Saafeen

Theses

After more than a century of investigation, it has become evident that cancer development and progression occur at the expense of a dysfunctional immune system. This realization has ushered cancer immunotherapy as a new modality of treatment. In the last decade, the use of immune checkpoint inhibitors to treat cancer patients resulted in unprecedented and durable clinical benefits. However, the response rate in many cancers remains rather modest, with colorectal cancer being at the lower end of the spectrum. Previous work from our laboratory demonstrated the efficacy of using attenuated bacteria as immunomodulatory anti-cancer agents. The current study investigated the …


Studying Neurotoxic Effects Of Three Synthetic Insecticides And Two Herbal Infusions On The Nervous System Of The Fruit Fly Drosophila Melanogaster, Sara Khamis Obaid Hamarain Al Dhaheri Nov 2021

Studying Neurotoxic Effects Of Three Synthetic Insecticides And Two Herbal Infusions On The Nervous System Of The Fruit Fly Drosophila Melanogaster, Sara Khamis Obaid Hamarain Al Dhaheri

Theses

Pesticides applied on plants and animals can reach the human diet once they enter food chains. Insecticides are neurotoxic agents; they have the potential of causing damage to the nervous system in people. The damage could induce or promote neurodegenerative diseases such as the Parkinson’s and Alzheimer's. It is well-documented that the exposure to the insecticide chlorpyrifos (CPF) stimulate the Parkinson disease in humans and experimental animals. Thus, this research project will study effect of three synthetic insecticides pirimicarb, tefluthrin, and CPF on the nervous system of Drosophila melanogaster as a model organism. In addition, the project will evaluate the …