Digital Commons Network^™

Using Authentic Online Resources In Russian For Stem Coursework For Novice Through Superior Level Learners, Molly T. Blasing

Modern and Classical Languages, Literatures and Cultures Faculty Publications

This article makes a case for incorporating STEM content into Russian language courses at the Novice through Superior levels of proficiency. The author presents models of asynchronous learning activities based on authentic online resources developed for a Russian for STEM pilot course taught during the COVID-19 pandemic. These lessons can be employed in online or face-to-face courses to prepare students to speak, read, write, and understand the language of STEM fields in Russian.

Effects Of Social Isolation On Perineuronal Nets In The Amygdala Following A Reward Omission Task In Female Rats, Dolores B. Vazquez-Sanroman, G. Arlington Wilson, Michael T. Bardo

Psychology Faculty Publications

Negative urgency is a facet of impulsivity associated with negative affect and risky behavior that may involve the amygdala. The current study determined if social isolation during development alters negative urgency and c-Fos activity in the basolateral amygdala (BLA). Female Sprague-Dawley rats were raised in an isolated condition (IC), a standard social condition (SC), or an enriched condition (EC) and then were tested for locomotor activity, novelty place preference, and negative urgency using a reward omission task. Following performance on the reward omission task, the brains were analyzed for c-Fos expression in Ca2+ /calmodulin kinase II (CaMKII) and calbindin (CB) …

Effects Of The Glucocorticoid Receptor Antagonist Pt150 On Stress-Induced Fentanyl Seeking In Male And Female Rats, Lindsey R. Hammerslag, Emily D. Denehy, Benjamin A. Carper, Tracy L. Nolen, Mark A. Prendergast, Michael T. Bardo

Psychology Faculty Publications

Rationale Opioid use disorder (OUD) is highly comorbid with stress-related disorders, and stress can serve as a trigger for reinstatement of drug seeking. Glucocorticoid receptor (GR) antagonists such as mifepristone (RU-486) may be effective against stress-induced drug seeking. In the current study, PT150 (formerly ORG-34517), a more selective GR antagonist, was tested using two models of stress-induced drug seeking, namely footshock and yohimbine.

Methods Adult male and female Sprague-Dawley rats were trained to self-administer fentanyl (2.5 μg/kg/infusion, i.v.) in a model of escalation. Rats then received 7 days of abstinence, followed by extinction; PT150 (0, 50 or 100 mg/kg in …

Laser-Scribed Graphene Electrodes As Inflammatory Biosensors (Laserflame), Pei Shee Tan

Theses

Laser-scribed graphene electrodes (LSGE) are a low cost, portable, flexible and ideal electrochemical platform approach as point of care biosensors. It is anticipated that integrating the detection of immune cell inflammatory cytokines with LSGEs may present a useful diagnostic platform for managing the risk of inflammatory diseases as early detection of inflammatory molecules could significantly improve the treatment and outcome of diseases induced by protracted inflammation, such as cancer, asthma and rheumatoid arthritis. This study proposed LSGE first time novel use in the detection of an inflammatory cytokine released by immune cells (monocyte THP-1 cell line), with high sensitivity and …

Comparison Of The Effects Of Land Use / Land Cover On Water Quality And The Intertidal Marine Macroalgae Communities At The Fluvial Outflows Of The Dingle Peninsula, Cassandra Lew

Theses

The Milltown, Feohanagh, and Owenmore river basins located on the Dingle Peninsula in Ireland were studied to see how variation in land use and land cover (LU/LC) affected water quality and the macroalgal communities at each river’s respective fluvial outflow. Abundance and composition of macroalgae in river and coastal water bodies have been designated as an indicator of water quality according to the Water Framework Directive 2000. The results of this study found that the Feohanagh’s macroalgal community had the highest species richness for most months while the Milltown had the highest Shannon Diversity Index. The Owenmore’s community was consistently …

Ectoparasitism Of The Feather Chewing Louse Colpocephalum Trichosum On The Andean Condor Vultur Gryphus, Pablo Sebastián Padrón, Anahi Hidalgo, Nicole Ormaza, Sebastián Kohn, Fabricio Narvaez, Félix Hernán Vargas

Neotropical Biodiversity

Feather chewing lice are common and important ectoparasites of birds. Here we report for the first time the presence of the ectoparasite, Colpocephalum trichosum Harrison1916 (Phthiraptera: Menoponidae on the Andean condor Vultur gryphus Linnaeus, 1758 from the North high Andes of Ecuador in Pichincha province. A total of 20 louse specimens were collected and analyzed from one free-living female juvenile host. Additionally, high resolution photographs of the louse are included, and a discussion on the potential implications of ectoparasites on the conservation of this threatened bird species is presented. Finally, we propose that further studies on Andean Condor ectoparasites should …

A Karst Feature Prediction Model For Prince Of Wales Island, Alaska Based On High Resolution Lidar Imagery, Alexander Lyles

Master's Theses or Doctor of Nursing Practice

Investigation into surface karst formation is significant to hazard prediction, hydrogeologic drainage, and land management. Southeast Alaska contains over 600,000 acres of mapped carbonate bedrock, and some of the fastest recorded karst dissolution in the world. The objectives of this study are to develop and compare multiple semi-automated models to map and delineate karst features from bare-earth LiDAR imagery using ArcGIS Desktop 10.7, and to apply a preliminary geostatistical analysis of sinkhole morphometric parameters to highlight potential spatial patterns of karst evolution on Prince of Wales Island, Alaska. A semi-automated approach of mapping karst features provides a dataset that minimizes …

Examining How Adverse Childhood Experiences And The Underlying Processes Of Trait And State Impulsivity Influence Suicidal Behavior, Julia K. Duran

Master's Theses or Doctor of Nursing Practice

ABSTRACT

Due to the effects of ACEs and impulsive behavior on mental and physical health, it is important to better understand the relationship between these two as well as how they both may influence choices, such as suicide. Numerous studies have identified impulsive behavior as a risk factor for suicide, however, recent research has identified several underlying independent processes that make up impulsivity. This study uses a broad assessment of trait and state impulsivity to gather a more discrete understanding of the underlying processes that contribute to impulsive behavior. The short version UPPS-P scale was used to measure negative urgency, …

Remembering The Experience Of War: A Sensory Study Of The Vietnam War And Collective Memory, Jacob Randolph

Master's Theses or Doctor of Nursing Practice

The Vietnam War is remembered in a variety of ways. It is remembered as a war against communism, yet one that was also against American ideals of freedom. It is remembered as a war of patriotism, yet one that was also against the numerous military members who fought in it. It is remembered as a war for integration and unity among black and white, yet many African-Americans remember the time period as a war being fought abroad and at home. Memory of the war is obviously contradicting, but then again the 1960s and 1970s oftentimes were.

This thesis examines how …

What Influences Suffering In Silence: Examining Mental Health Stigma, Social-Cognitive Factors, And Age As Predictors Of The Willingness To Seek Professional Psychological Help, Bobbie Call

Master's Theses or Doctor of Nursing Practice

Mental health and wellness are increasingly common and popular topics discussed and researched in the world today. Recent estimates suggest that one in five adults in the United States of America experience mental health issues each year; this is estimated to be approximately 51.5 million adults (NAMI, 2020). However, despite many individuals who might suffer from mental health issues, and perhaps be diagnosed with a mental health disorder, these same individuals may not seek out the help and psychological services needed. Research exploring why people do not seek out help for their mental health should be a priority. Thus, the …

Ecological Controls On The Campanian Distribution Of Hesperornis (Aves: Hesperornithiformes) In The Western Interior Seaway, Blake Chapman

Master's Theses or Doctor of Nursing Practice

The epicontinental Western Interior Seaway (WIS) of Late Cretaceous North America provided a unique marine habitat for cephalopods, fish, marine reptiles, and the foot-propelled diving seabird Hesperornis. While several predator-prey relationships among Hesperornis or other hesperornithiforms and other WIS animals have been hypothesized based on gut contents, bite marks, and coprolites/colonites, ecological relationships have not been quantitatively tested. Paleontological species distribution modeling (SDM) studies have focused on extinct non-marine taxa and marine invertebrates, with only two marine vertebrate studies of extant taxa. Here, two SDM methods were used to test the influence of vertebrate faunas, sedimentary rock type, paleogeography, …

Lights, Camera, Activity! A Systematic Review Of Research On Learner-Generated Videos, Bridgette Shade Epps, Tian Luo, Pauline S. Muljana

STEMPS Faculty Publications

Aim/Purpose

The current literature discusses the use and benefits of learner-generated videos (LGVs). However, it rarely addresses any correlation between the types of subjects that are best suited for using these videos or what techniques should accompany the use of LGVs.

Background

This systematic review synthesizes current literature to identify patterns and implications that develop from the use of LGVs so that their future use can be both consistent and effective. This paper also reviews the studies to establish the most consistent educational benefits that emerge from this activity.

Methodology

Employing the Preferred-Reporting of Items for Systematic Reviews and Meta-Analyses …

Policy Analysis Of Emissions Cap And Trade: The United State And The European Union, Drew Bealby

Master's Theses or Doctor of Nursing Practice

Effects of climate change are appearing each day therefore proactive steps need to be made to reduce these effects. The National Aeronautics and Space Administration (NASA) notes that humans producing greenhouse gases (GHGs) such as carbon dioxide (CO₂), methane, and nitrous oxide are the main reason the Earth’s overall temperature is rising (NASA 2019). A policy analysis was done on the European Union Emissions Trading Scheme (EU ETS) along with comparisons to the United States’ emissions policies that are in place currently. The European Union (E.U.) itself is both an economic and political union of 27 countries in …

An Investigation Into Historical And Contemporary Breeding Occurrence Of The Ferruginous Hawk In Kansas, Erica Clark

Master's Theses or Doctor of Nursing Practice

The Ferruginous Hawk (Buteo regalis) is the largest Buteo species occurring in grasslands, nesting along bluffs, buttes and isolated trees. In Kansas, the Ferruginous Hawk is listed as a Species of Greatest Conservation Need, Tier II. A previous study on Ferruginous Hawks nesting in Kansas during the years of 1979 to 1987, with sporadic visits from the 1990s to 2000, revealed that the most productive nesting territories were inaccessible to predators, placed on rocky ledges and the surrounding landscape was over 50% rangeland. I revisited 82 of the 111 historic nest territories in the summers of 2019 and …

Multi-Label Classification On Locally-Linear Data: Application To Chemical Toxicity Prediction, Xiu Huan Yap

Browse all Theses and Dissertations

Computational models may assist in identification and prioritization of large chemical libraries. Recent experimental and data curation efforts, such as from the Tox21 consortium, have contributed towards toxicological datasets of increasing numbers of chemicals and toxicity endpoints, creating a golden opportunity for the exploration of multi-label learning and deep learning approaches in this thesis. Multi-label classification (MLC) methods may improve model predictivity by accounting for label dependence. However, current measures of label dependence, such as correlation coefficient, are inappropriate for datasets with extreme class imbalance, often seen in toxicological datasets. In this thesis, we propose a novel label dependence measure …

Cytoviva Hyperspectral Imaging For Comparing The Uptake And Transformation Of Agnps And Ag+ In Mitochondria, Kristina Steingass

Browse all Theses and Dissertations

Nanomaterials have attracted significant attention in the last decade, with applications in everyday products. Amongst all known nanomaterials in use, silver is the leading metal, present in 531 different types of products, owing to their unique optical, electrical, antimicrobial, and thermal properties. Though silver nanoparticles (AgNPs) come in contact regularly with the general population, there is little known about their toxicity mechanism due to limited techniques for thorough analysis. CytoViva Hyperspectral Imaging (HSI) shows potential for filling these gaps. In this study, borohydride-capped AgNPs with an approximate diameter of 10 nm were synthesized using the modified Creighton method and characterized …

The Effect Of Endogenous Ligands Of The Aryl Hydrocarbon Receptor On Antibody Expression In A Human B-Cell Model, Valerie Benedict

Browse all Theses and Dissertations

Small changes in antibody expression have broad impacts on human health and disease. An environmental toxicant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induces profound immune suppression in animal models in an aryl hydrocarbon receptor (AhR)-mediated fashion. In a human Burkitt's lymphoma cell line (CL-01), TCDD inhibited IgG secretion and differentially impacted Ig heavy chain expression. In addition to TCDD, the AhR has several endogenous, dietary, and bacterial ligands such as 6-formylindolo[3,2-b]carbazole (FICZ) and indole, which are present within the human body at varied concentrations (0.30 mM- 6.64 mM). Both FICZ (100 nM) and indole (100 µM) significantly reduced IgG secretion. Overall antibody secretion is …

Il-10 And Tgf-Beta Increase Connexin-43 Expression And Membrane Potential Of Hl-1 Cardiomyocytes Coupled With Raw 264.7 Macrophages, Cora B. Cox

Browse all Theses and Dissertations

Cardiomyocytes and macrophages have been found to interact via connexin-43 hemichannels. The role of connexin-43, however, is not fully understood. This study shows that these interactions aid in increasing the membrane potential of cardiomyocytes allowing contraction of the cells. HL-1 cardiomyocytes and RAW 264.7 macrophages in coculture increased expression of connexin-43 compared to cardiomyocytes alone. Co-cultures also increased the fluorescence of Di-8-ANEPPS potentiometric dye indicating an increase in cardiomyocyte membrane potential. Treatment with IL-10 and TGF-beta further increased connexin-43 expression and membrane potential. Treatment with SOCS3 inhibited the effects of TGF-beta and IL-10 while having no effect on its own. …

Nature's Converts: Reading The Land And Nature In The Early American Conversion Narrative, 1727-1831, Cullen Rex Brown

Electronic Theses and Dissertations

This dissertation examines the connections between cultivating the land and cultivating the soul through select readings of early American conversion narratives composed between 1727-1831. Over a century after British Colonists colonized the shores of New England, members of the United Ministers of Boston championed the efforts of their descendants, who both cultivated the land and the Indigenous and new arrived souls emplaced within the North American landscape. As they told their readers in 1727, their dual cultivating efforts were worthy of universal adulation and imitation. And in 1836, the words of Reverend Nahum Gold echoed those of the United Ministers …

Topics On Applications Of Optimization Theories On Statistical Methodologies, Duc Anh Anh Doan

Electronic Theses and Dissertations

In this dissertation, We show the results of our researches in statistical sampling, functional optimization, and methodology for partially observed Markov process (POMP) models. In statistical sampling, we introduce a p-generalized smoothing method that enables the Langevin-Monte Carlo method to generate a sample from a log concave distribution weakly smoothing potential function. For our optimization research, we introduce an accelerated inexact gradient (AIG) method. Combining the strengths while mitigating the weakness of its parent methods: gradient descent and Nesterov's accelerated gradient, AIG converges with excellent rates for both convex and non-convex optimization problems for smooth objective functions. Furthermore, we also …

Methylene Blue As Light And Reactive Oxygen Species Sensitive Ligand: Appicability In Hybrid Drug And Material Synthesis, Huy Dao

Electronic Theses and Dissertations

Methylene blue (MB) with a 10-N-carbamoyl linkage was discovered and developed as a multifunctional far-red (660 nm) photocleavable ligand capable of rendering a series of MB conjugated compounds with off-to-on fluorescence switch properties through the controlled release of MB. The released MB was successfully demonstrated to be an effective photosensitizer, imaging probe, and therapeutic agent. The complete release of MB was achieved with a cumulative light dose of 15 J/cm2. The photosensitivity was demonstrated to be dependent on the type of chemical bond at 10-N of the phenothiazine ring which links MB to a side group. Specifically, the urea bond-based …

Decreasing Discipline Disparities Among African-American Males: An Applied Research Study On The Effects Of Developing Culturally Responsive Teaching Practices Among Teachers And Equipping Students With Added Supports, Reginald Maurice Herrington

Electronic Theses and Dissertations

Schools and school leaders are charged to provide equitable educational opportunities and ensure the success for all students no matter their scholastic ability giving students access to an education that is culturally responsive. Despite this charge, African-American male students receive exclusionary punishment at disparaging rates which contributes to the widening achievement gap between white and black students. The purpose of this applied research study was to decrease the rate at which African-American males are referred to the office. This study analyzes the implementation of two elements: engaging teachers in a book study on culturally responsive teaching strategies and targeted counseling …

Subcutaneous Delivery Of Albumin, Vy Nguyen

Electronic Theses and Dissertations

An increasing number of protein drugs are used in the clinic to treat a broad range of diseases. However, because of their large molecular sizes and high hydrophilicity, protein drugs are not orally bioavailable, which commonly require intravenous, intramuscular or subcutaneous injection. Thermosensitive polymers have been widely investigated as in situ depots for sustained drug release delivered through subcutaneous route.Albumin is the most abundant proteins in bloodstream. It has long half-life (19 days in human) and plays important roles such as acting as carrier for fatty acids, amino acids, waste products and medical compounds. Albumin has been studied for decades …

Equity, Social Justice, And Ethical Responsibility In Higher Education: Voices Of Business Students At A Pervasivley Sectarian University, Van Brooks Poole

Electronic Theses and Dissertations

This proposed study explores the perceptions and experiences of business students who attend a pervasively sectarian university in the South (MPSU) regarding their perceptions of equity, social justice, and ethical responsibility through their experiences on campus and in their academic program. This study will discuss socio-political influences at the national, state, and local levels and examine existing university policies and practices to identify recommendations for organizational change using Lewin’s unfreezing model as a theoretical framework.

Microbial Community Responses To Salinification: Applications In Climate Change And Extreme Environments, Eric Weingarten

Electronic Theses and Dissertations

Sediment microbial community responses to elevated salinity are important in predicting the effects of sea level rise as well as in understanding those communities that can thrive in extreme environments. In this dissertation, I use natural and field experiments to investigate how salinity influences microbiome structure in coastal wetlands. Through the use of amplicon sequencing, I demonstrate that there are compositional differences between the microbiota of four wetland salinity classes: limnetic, oligohaline, mesohaline, and polyhaline. These results were reciprocated in a microcosm study exposing freshwater sediment to meso- and polyhaline conditions, showing that communities shifted proportionally to the magnitude of …

Carbon Nanotube-Coated Scaffolds For Tissue Engineering Applications, Soham Dipakbhai Parikh

Browse all Theses and Dissertations

Carbon Nanotubes (CNTs) have beneficial properties for cell scaffolding, which has translated into effective growth of bone, muscle, and cardiac cells. However, loose carbon nanotubes can cause in vivo toxicity. To reduce this risk, our team has developed biomimetic scaffolds with multiscale hierarchy where carpet-like CNT arrays are covalently bonded to larger biocompatible substrates. In this study, we have tested such scaffolds in two distinct types of biomedical applications involving glioblastoma and keratinocyte cells. The growth of glioblastoma (GBM) cells on our CNT-coated biomimetic scaffolds was evaluated to check their suitability as a potential chemotherapy-loaded implant for GBM patient treatment. …

Epigenetic Regulation In Brevundimonas Subvibrioides And Comparison With The Caulobacter Crescentus Model, Satish Adhikari

Electronic Theses and Dissertations

Epigenetics is a form of DNA methylation-based gene regulation. The CcrM methyltransferase and transcriptional regulator GcrA, constitute an epigenetic regulatory system well-conserved throughout the Alphaproteobacteria. The regulatory targets of GcrA and CcrM were identified in the Alphaproteobacterium Brevundimonas subvibrioides, and then compared to those of its close relative Caulobacter crescentus. Both these bacteria belong to the same family and inhabit the same environment. Although the regulators themselves are highly conserved, the genes they regulate are vastly different. GcrA directly regulates 204 genes in C. crescentus, and though B. subvibrioides has orthologs to 147 of those genes, only 48 genes retained …

The Perceptions That Um First-Generation College Students Have Regarding The Impact Of Campus Engagement On Their Success At The Institution, Martin B. Fisher

Electronic Theses and Dissertations

First-generation students are often underprepared for college and have lower persistence rates (Balemian & Feng, 2013), and they face a unique set of challenges in their transition to college that many of their peers do not (Pelco, Bell, & Lockeman, 2014). Consistent with national statistics, data obtained from UM’s Office of Institutional Research, Effectiveness, and Planning indicate first-generation students at UM persist and graduate at lower rates than their peers whose parents have a bachelor’s degree.

There are many reasons why first-generation students have lower success rates, and, for some students, a lack of engagement is one of them (Pascarella, …

Fabrication And Characterization Of Ocular Inserts By Hot Melt Extrusion And 3d Printing, Meghana Mokashi

Electronic Theses and Dissertations

Hot melt extrusion (HME) has emerged as a viable approach for a wide range of pharmaceutical applications over the last few decades. The HME method is more efficient than other traditional technologies due to its high throughput, low residence time, lack of organic solvents, and a combination of intensive mixing and controlled temperature. Because of the ability to construct complex and personalized dosage forms depending on the requirements of the patient, three-dimensional printing (3DP) is an emerging approach in the fabrication of pharmaceutical dosage forms. The objective of the current study is to fabricate Lidocaine HCl ocular inserts by HME …

A Numerical Study Of The Effects Of Time-Varying Streambed Conductivity On Groundwater – Surface Water Interactions During Storm Events, Jiayu Fang

Electronic Theses and Dissertations

Streambed conductivity is widely recognized as a vital parameter controlling the stream-aquifer exchange. Many field measurements have revealed that temporal variation of streambed conductivity is rapid and dramatic during floods. However, previous numerical studies either assumed streambed conductivity as steady over storm events or focused on time-varying streambed conductivity during low-stage periods. This study aims at bridging this gap by both incorporating time-varying streambed conductivity into a numerical model of groundwater (GW) – surface water (SW) interactions and simulating them under different flooding conditions, making this dissertation the first modeling study to explore combined effects of high-stage events and time-varying …