Digital Commons Network^™

Come As You Are: Islamic Religiousness As A Context For Mental Illness Beliefs And Treatment, Elijah Phoenix Mudryk

Electronic Theses and Dissertations

The United States is home to approximately three million Muslim-Americans, a diverse and growing demographic group that has woven itself into the fabric of American life. Hailing from many regions around the world, Muslims in the U.S. are varied in racial and ethnic backgrounds and not dominated by any particular race or ethnicity. National pride and a strong religious identity are shared aspects among U.S. born Muslims and immigrants alike (Pew, 2018). In addition to the typical challenges of daily life, Muslim-Americans have experienced high levels of religious and ethnic discrimination. Post-9/11, Muslim-Americans suffered a 1600% increase in reported hate …

Exploring Copper Active Sites In Biology With Relevance To Alzheimer's Disease And De Novo Designed Biocatalysts, Suchitra Mitra

Electronic Theses and Dissertations

Copper is one of the most abundant and less toxic metal on earth. In nature, a variety of proteins have copper in their active site structure. Copper bound to amyloid proteins are implicated to play pathophysiological roles in neurodegenerative diseases. On the other hand, copper containing metalloenzymes in Nature catalyze important biochemical reactions. Cu containing metalloenzymes play a significant role in a variety of functions viz. electron transfer, oxygen reduction, oxygen transport, and substrate oxidation owing to the readily available redox states of Cu+/Cu2+. While Cu bound to amyloid proteins that are often referred as intrinsically disordered or misfolded proteins …

Acoustic Bessel And Vortex Beams: Forces And Refraction, Xudong Fan

Electronic Theses and Dissertations

Non-contact manipulation techniques or tweezers devices are invaluable for applications in physics, chemistry, biology, and engineering. Acoustic tweezers using either standing waves or focused beams have been investigated for more than a few decades with advantages of label-free operation, noninvasiveness, and biocompatibility when compared with the optical, magnetic, and electrical counterparts. Here, a new type of acoustic tweezers (i.e. acoustic tractors) is studied using acoustic Bessel and vortex beams that are able to pull objects against the beam's propagation over centimeter ranges. Stable acoustic tractors require transversely stable trapping in addition to axially negative pulling. Hence, the transverse forces acting …

Applications Of Fluoronitroalkenes In 1,3-Dipolar Cycloaddition And 1,4-Conjugate Addition, Hamdan Eid Alrefaei

Electronic Theses and Dissertations

Fluorinated compounds have been routinely synthesized in the pharmaceutical and agricultural industries. Approximately, 45% of drugs approved by the U.S. Food and Drug Administration in 2018−2019, and 52% of agricultural products between 2010 and 2017 were fluorinated compounds. In comparison to their non-fluorinated counterparts, fluorinated drugs have different pharmacokinetics and pharmacodynamics profiles. Bond strength and electronegativity of the fluorine atom can affect the compound's pKa, dipole moment, and metabolic stability. Therefore, methods to access fluorinated compounds are highly pursued in organic synthesis. Various fluorinating agents (nucleophilic and electrophilic) have been developed over the last few decades and are widely employed …

Black Girls Work Out Too! An Exploration Of Physical Activity Behaviors Of Black Women, Kimberley C. Desir

PCOM Psychology Dissertations

Lack of participation in physical activity has become an increasing public health concern in the United States. Compared to any other racial and ethnic group, Black women have the lowest prevalence of exercise. A limited amount of empirical research suggests cultural beliefs about the meaning of physical activity has a role in one’s ability to initiate and maintain a physical activity regimen. Black women face specific sociocultural factors that impact their physical activity routines. Hair care practices and maintenance has been identified as a unique barrier among Black women. This qualitative research study investigated the influence of the distinctions in …

Structured To Fail: Lessons From The Trump Administration's Faulty Pandemic Planning And Response, Alejandro E. Camacho, Robert L. Glicksman

GW Law Faculty Publications & Other Works

The Trump Administration’s response to the COVID-19 pandemic is a stark reminder that poorly designed government can be a matter of life and death. This article explains how the Administration’s careless and delayed response to the crisis was made immeasurably worse by its confused and confusing reallocation of authority to perform or supervise tasks essential to reducing the virus’s ravages.

After exploring the rationale for and impact of prior federal reorganizations responding to public health crises, the article shows how a combination of unnecessary and unhelpful overlapping authority and a thoughtless mix of centralized and decentralized authority contributed to the …

Navigating Internalized Stigma And Identity Development In Bipolar Disorder I: A Grounded Theory Investigation., Kaylyn L. Watterson

Electronic Theses and Dissertations

Mental illness stigma occurs at multiple levels in Western societies. Internalized stigma, the application of negative stereotypes and prejudice about mental illness to self-concept, has deleterious effects on mental health for adults living with a serious mental illness. Historically, research on stigma in serious mental illness has centered on schizophrenia. Recently, researchers and clinicians have drawn attention to bipolar disorder I, an affective disorder that creates disruptions in functioning and increased risk for substance abuse and suicide. Despite the growing literature establishing the relationship between recovery in serious mental illness and identity, little is known about how adults in long-term …

Evaluation Of Murrell’S Ekf-Based Attitude Estimation Algorithm For Exploiting Multiple Attitude Sensor Configurations, Sharanabasaweshwara Asundi, Norman Fitz-Coy, Haniph Latchman

Mechanical & Aerospace Engineering Faculty Publications

Pico- and nano-satellites, due to their form factor and size, are limited in accommodating multiple or redundant attitude sensors. For such satellites, Murrell's implementation of the extended Kalman filter (EKF) can be exploited to accommodate multiple sensor configurations from a set of non redundant attitude sensors. The paper describes such an implementation involving a sun sensor suite and a magnetometer as attitude sensors. The implementation exploits Murrell's EKF to enable three sensor configurations, which can be operationally commanded, for satellite attitude estimation. Among the three attitude estimation schemes, (i) sun sensor suite and magnetometer, (ii) magnetic field vector and its …

Prevalence And Exacerbation Of Asthma Within Two Counties In Eastern Kentucky, Rachid Souleye

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Background: Central Appalachia residents have one of the highest rates of serious respiratory diseases in the nation. Appalachian Kentuckians are 50% more likely to be diagnosed with adult asthma compared to the overall U.S. population. Yet, few epidemiologic studies have assessed risk factors for respiratory disease in this population. Using a community-based approach, the investigators of the Mountain Air Project (MAP), one of the largest adult cohorts from two disadvantaged communities in Central Kentucky, collected data to estimate the prevalence of asthma and assess various socioeconomic and environmental risk factors to determine their effect on asthma.

Methods: A cross-sectional epidemiologic …

Healthy Living People: A Hiv Transmission Intervention In Four Chicago Communities, Angela Wuerger

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

The transmission of HIV within the city of Chicago has been established as a major health concern: however, the lack of adequate resources has created gaps within current programming available for people living with HIV. Healthy Living People (HLP) is an evidence-based program focused on reducing the transmission of HIV through strengthening adherence to antiretroviral therapy and decreasing number of higher risk sexual encounters. The Chicago Department of Public Health will provide the HLP program, which includes fifteen 90-minute sessions over the course of one year. The HLP program will be offered for people living with

HIV in four Chicago …

Can Treatment Of Social Isolation And Loneliness Reduce Healthcare Utility? An Analysis Of Social Prescribing, Matthew Mattingly

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

The paper focuses on the practice of social prescribing as it is currently implemented through the National Health Service (NHS) of the United Kingdom. Social Prescribing is an emerging healthcare intervention aimed at referring patients to community-based activities. NHS promotes social prescribing as a method of reducing healthcare utilization in chronically ill patients. Current evidence on social prescribing is subject to significant variation and has not supported NHS’s claims. The potential link between feeling of social isolation, loneliness and chronic illness was further investigated through data from the National Social Life, Health & Aging Project (NSHAP). Data was tested for …

Rabies In Kentucky From 1989-2020: A Case For Surveillance, Sarah Jane Robbins

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

The Kentucky rabies reporting system includes data from five laboratories and provides an account of suspected rabies reports since 1989. Over 35,000 suspected cases are used to estimate rabies incidence temporally and spatially. Recommendations to the current rabies reporting methodologies are presented through proposed innovations of a standard, electronic reporting form. Given the multiple sources of data, the reporting system lacks standardization and comprehensive information about suspected rabies events, resulting in limited epidemiological capabilities; and data issues that prevent its use as a surveillance system. These issues are a limiting factor in rabies elimination; but a driving factor in over-testing, …

Maternal Residential Proximity To Surface Mining Associated With Preterm Birth And Low Birth Weight In Appalachian Kentucky, Whitney Smith

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Objective: This study aims to examine the relationship between maternal residency in a county with surface coal production and preterm birth or low birth weight.

Methods: A cross-sectional study was conducted using birth records (n=62,766) for 54 Appalachian counties and coal production in tons. Logistic regression and chi-squared analysis was done to analyze the relationship between surface coal mining and preterm birth and low birth weight in two different birth groups.

Results: After controlling for covariates, statistically significant increases were seen in Birth Group 1 and Birth group 2. Birth Group 1 had statistically significant results for preterm birth ((1.19 …

Assessment Of The University Of Kentucky's Nutrition Education Program's Smarter Lunchrooms Pilot Plate Waste Project In Three Kentucky Schools, Natalie Jones

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

School-based approaches utilizing policy, systems, and environmental strategies are needed to address the complex factors driving childhood obesity. The purpose of this pilot study is to implement Smarter Lunchroom strategies in three participating Kentucky middle schools in 2019 and then assess two outcomes: (1) determine the impact of the intervention on fruit and vegetable purchases and waste, and (2) determine how purchases or waste varied by interventions selected for each setting. After the 6-week intervention, combined we found no statistical significant increases in fruit and vegetable purchasing from pre to post-intervention. No statistical significant decreases in fruit and vegetable plate …

A Case Study To Explore The Perception Of A Woman Participant In Drug Court Of A Community-Based Arts Program On Substance Use Recovery Outcomes, Catherine L. Troop

Theses and Dissertations--Early Childhood, Special Education, and Counselor Education

Addiction to drugs is a complex, chronic, and multi-faceted disease that often involves cycles of relapse and remission. The lifetime prevalence of alcohol and drug use disorders in women in the United States is 19.5 percent and 7.1 percent, respectively (McHugh, Wigderson, & Greenfield, 2014) yet there is a significant dearth of efficacious substance abuse treatment services tailored specifically to women. In addition, literature suggests that the third aspect of Bandura’s Social Cognitive theory (self-efficacy) potentially plays a significant role in abstinence of drug use. The role of art interventions on recovery outcomes for a woman enrolled in the Franklin …

The Relationship Between Stress And Quality Of Life In People With Multiple Sclerosis: The Mediating Role Of Resilience, Byung Jin Kim

Theses and Dissertations--Early Childhood, Special Education, and Counselor Education

Multiple sclerosis (MS) is a chronic disease of the central nervous system encompassing the brain, spinal cord, and optic nerve, in which the patient’s immune system attacks healthy cells and tissues. Due to the unpredictable characteristics of the disease, MS can lead to an unusually high level of stress and may negatively impact the individual’s QoL. Resilience is a psychological structure that shows positive coping and adaptive ability from difficult or stressful situations. Resilience also indicates a buffering effect on the stressors of individuals with disabilities and serves to protect psychological health and function from disability. The purpose of this …

Digital Twins For Manufacturing And Logistics Systems: Is Simulation Practice Ready?, Francesco Longo, Antonio Padovano, Letizia Nicoletti, Mohaiad Elbasheer, Rafael Diaz

VMASC Publications

This article provides a theoretical contribution to the state-of-the-art of digital twins for manufacturing and logistics systems. The primary goal of this paper is to draw attention to the gap between the theoretical framework of digital twins in manufacturing and supply chain and their practical implementation from a simulation modeling point of view. Therefore, highlighting the recent innovations in the simulation practice that could provide the basis for digital twins with high levels of data integration, automation, and smart capabilities. This study follows a comparative approach to analyzing theoretical and technical readiness for developing digital twins with high fidelity and …

The Effect Of Different Drilling Protocols On Bone Healing Around Dental Implants., Sara Fikry, Amr Amin Ghanim, Hisham El Sheikh, Omar El Sergany

Dentistry

Materials and Methods: 20 patients with kennedy class III modification 1 edentulous areas were recruited for this study and divided into two groups; Control group received implants with conventional osteotomy preparation following standard drilling protocol (speed= 1200 rpm) with torque of 30N and sufficient saline irrigation, while Study group received implants with osteotomy preparation following a low speed drilling protocol (speed < 200 rpm) without irrigation and a torque of 50 N. Cone Beam CT was used to evaluate bone height and density around the implants at 3, 6 and 12 months after insertion. Implant primary stability was evaluated using Ostell by Resonance Frequency Analysis. Results The results showed no significant difference between bone height changes and densities in the control and study groups. Implants primary stability also showed no significant difference in ISQ values between both groups. Conclusion Biologic drilling is a promising implant drilling protocol with a potential to insert implants showing successful osseointegration and acceptable bone changes.

Evaluation Of Anti-Cancer Effect Of Different Concentrations Of Black Raspberries Extract On Oral Squamous Cell Carcinoma Cell Line (In Vitro Study), Sara Abdelwahed

Dentistry

Background: Black Raspberry has a wide range of pharmacological and therapeutic aspects including anti-inflammatory and antioxidant activities. Moreover, the effect of Black Raspberry has been studied in many cancers such as human cervical, esophageal and colorectal cancer and showed cytotoxic and anti-proliferative effects against these types of cancer. Aim: To identify the possible anti-cancer effect of Black Raspberry on Oral Squamous Cell Carcinoma cell line. Material and methods: Human tongue squamous cell carcinoma cell line was divided into 3 groups: one control group, second group treated with Black Raspberry, and the third group treated with Doxorubicin, each of the two …

Systemic Versus Local Injection Of Bone Marrow Mesenchymal Stem Cells On 5-Fluorouracil Treated Parotid Glands Of Albino Rats, Caroline Maged Massieh, Medhat El Zainy, Reham Magdy Amin, Iman Fathy

Dentistry

ABSTRACT Objective: Head and neck cancer is the sixth leading cancer by incidence worldwide and eighth by death. Recent reports revealed that, not only radiotherapy but also chemotherapy may induce xerostomia. The aim of this study was to compare the possible regenerative effect of BMSCs through systemic and local injections. Material and Methods: 52 male Albino rats were randomly divided into 4 groups: Group 1: 10 rats received 0.5 ml of PBS by injection. Group 2: 14 rats received an intraperitoneal injection of 5-FU drug. Group 3: 14 rats were injected the same dose of 5-FU then received an intraglandular …

In Vitro Evaluation Of Material Dependent Force Damping Behavior Of Implant-Supported Restorations Using Different Cad-Cam Materials And Luting Conditions, Ahmed Sabet

Dentistry

Statement of problem. Although force-damping behavior that matches natural teeth may be unobtainable, an optimal combination of crown material and luting agent might have a beneficial effect on the force absorption capacity of implant-supported restorations. However, the force-absorbing behavior of various restorative materials has not yet been satisfactorily investigated. Purpose. The purpose of this in vitro study was to evaluate the material dependent force-damping behavior of implant-supported crowns fabricated from different computer-aided design and computer-aided manufacturing (CAD-CAM) materials luted to implant abutments under different conditions. Material and methods. Titanium inserts (N=84) were screwed to implant analogs, scanned to design zirconia …

Factors Influencing Mare Milk And Foal Gastrointestinal Health, Morgan Brewer Pyles

Theses and Dissertations--Animal and Food Sciences

Foals are born lacking a functional microbial community in their gastrointestinal tract (GIT). However, these microbes quickly colonize after birth. Factors influencing the process of microbial colonization and health of the foal’s gastrointestinal tract, such as milk yield and composition, are not well understood. Milk contains non-lactose carbohydrates termed “oligosaccharides”, which serve as prebiotics in human neonates and may serve a similar function in foals. Three animal studies were conducted to evaluate factors influencing mare milk and digestive health in the foal. In experiment 1, bacteria were enumerated and identified in foal feces and the utilization of different carbohydrates by …

The Effect Of Endophyte-Infected Tall Fescue Seed Consumption On Gut And Satiety Hormones Related To Intake Regulation In Holstein Steers, Mindy Elizabeth King

Theses and Dissertations--Animal and Food Sciences

Cattle consuming endophyte-infected tall fescue (E+) typically experience a syndrome termed fescue toxicosis which is thought to be caused by ergot alkaloids produced by the endophyte. The most abundant alkaloid, and considered the most likely cause of the syndrome, is ergovaline (ERV). During fescue toxicosis, a decrease in ADG is observed which is likely due to the decrease in DMI commonly observed in animals consuming E+ compared to animals consuming non-endophyte-infected tall fescue (E-). However, the cause of the decrease in intake is not well elucidated. Many physiological responses control feed intake including, but not limited to, physical, neural, metabolic, …

Isolation Box Test (Ibt) And Dairy Calf Personality Traits Relationship With Performance Through Weaning, Megan Marie Woodrum Setser

Theses and Dissertations--Animal and Food Sciences

Personality tests are utilized to characterize individual differences in personality traits across species. Currently, there is no objective personality test that can be implemented on-farm to measure personality in dairy calves. Measuring personality of youngstock in the dairy industry may allow producers to utilize information on individual differences for management decisions and limit the investment in unfit individuals. The isolation box test is a personality test that has potential to be adapted and utilized for dairy calves. The main objective of this thesis is to develop, validate, and utilize an isolation box test for use on-farm in dairy calves. More …

Oral Mucormycosis In Post-Covid- 19 Patients: A Case Series, Enji Ahmed Mahmoud, Asmaa Abobakr, Radwa Raghib, Ayman El-Gawish, Dalia Galwash

Dentistry

No abstract provided.

Effect Of Locally Delivered Melatonin As An Adjunct To Nonsurgical Therapy On Gcf Antioxidant Capacity And Mmp-9 In Stage Ii Periodontitis Patients: A Randomized Controlled Clinical Trial, Enji Ahmed Mahmoud, Olfat Gamil Shaker, Nermin Youssif, Dalia Mohey-Eldien Ghalwash

Dentistry

Objectives. Periodontitis is characterized by inflammatory destruction of periodontal tissue, loss of attachment, and bone resorption. +e increase in reactive oxygen species (ROS) is responsible for the oxidative damage occurring in periodontal tissues. Melatonin has important immunomodulatory, anti-inflammatory, and powerful antioxidant functions. +e current study was carried out to evaluate the effect of topical melatonin gel as an adjunct to nonsurgical periodontal therapy. Methods. +is splitmouth randomized controlled clinical trial was performed on 24 patients with grade II periodontitis. Two sites in each patient were randomly assigned; test sites were treated by nonsurgical therapy followed by intrapocket application of 5% …

Sem And Energy Dispersive X-Ray Evaluation Of Smear Layer Removal Using Standard And Innovative Irrigation Protocols: A Comparative In Vitro Study, Hala Khalil, Lamia Ibrahim

Dentistry

ABSTRACT

Aim: Compare efficacy of Dual Rinse HEDP with sodium hypochlorite to sodium hypochlorite in combination with a finishing rinse with 17% EDTA solution to remove the smear layer.

Materials and methods: Sixteen human maxillary single-rooted, single canalled sound premolars were used. Specimens were distributed into 2 groups and labeled according to irrigation protocol used. Each group consisted of 8 specimens: Group 1 50% NaOCl followed by 17% EDTA. Group 2 The Dual Rinse® HEDP mixed with 50% NaOCl. Roots were prepared for SEM appraisal. The smear layer was assessed and scored. Energy-dispersive X-ray analysis was used to analyze the …

Prosocial Behaviors, Gross Motor Abilities, And Soccer Skill Acquisition Of Preschool-Aged Children, Julia Gomes

PCOM Psychology Dissertations

The psychosocial and physical benefits of organized sports participation for school-aged children, collegiate athletes, and professional athletes is well understood and recognized in the literature; however, less is known about the possible benefits of sport participation for preschool-aged children. The objective of the study was to examine whether children’s involvement in an organized team sport program facilitated their gross motor, soccer skill, and prosocial development, as well as their soccer experiences. This study examined participants between the ages of 1.5 and 4.5 years old, who were first time participants of a soccer program. To examine the research questions, a paired …

Assessing Factors That Increase The Likelihood Of Naloxone Administration, Samantha Nagy

PCOM Psychology Dissertations

For more than two decades, the opioid epidemic has swept through the United States and has caused thousands of deaths every year due to opioid overdose. The Centers for Disease Control and Prevention (CDC; 2019) has reported that since 1999, over 770,000 Americans have died from overdoses. Nearly 70% of deaths in 2018 were due to opioids, 47% of which were the result of fentanyl or a non-methadone opioid and 22% were the result of heroin (CDC, 2019). As policy and treatment protocols attempt to manage those who seek treatment, the pharmaceutical industry has developed a life-saving medication that gives …

The Relationship Between Insomnia, Sleep Continuity Disturbance, Sleep-Related Daytime Dysfunction, Problem Endorsement, And Aging In A Community-Based Sample, Julia T. Boyle

PCOM Psychology Dissertations

Although older adults experience greater difficulty initiating sleep, maintaining sleep, or waking up earlier than intended, they are less likely to report that they perceive this to be a problem. The discordance between sleep disorder symptoms and the reported perception that they are troubling is unusually prevalent among older adults. This may be problematic, in that individuals who do not perceive their sleep continuity disturbances (SCDs; difficulty falling asleep, staying asleep, or waking up earlier than intended) to be problems are less likely to seek treatment. Untreated SCD has been shown to be a risk factor for the development or …