Digital Commons Network^™

The Emotional Heschel, Maria Junttila Carson

Dissertations - ALL

This dissertation asserts that Heschel's work ought to be viewed as affective and emotional. Understanding Heschel's work as both creating and encouraging particular affects enables a more robust and fuller understanding of American Jewish postwar life. Specifically, American Jewish postwar life was animated by a nostalgia for the shtetl, a desire to connect with the State of Israel, a longing to create meaningful Jewish ritual, and uncertainty about the place of American Jews in broader social justice movements. Heschel views humans as interconnected in a web of affects and emotions; through affects, humans are connected to God, history and memory, …

Comparing Effectiveness And Perceived Characteristics Of Active Learning Methods In Undergraduate Biology Education, Linda R. Pesciotta

Dissertations - ALL

Although many undergraduates begin college as STEM majors, attrition rates from the field are high and numerous reports suggest that evidence-based teaching methods are critical for retention. Despite educators' research and near consensus that active learning is more effective than lecture, there are many types of active learning and the literature indicates their effects are not equivalent. The purpose of the current study was to directly compare different kinds of active learning by assessing their correlation with student performance (including learning gains) and understanding students' perceptions of them (including whether they contained Merrill's five principles of instruction and/or met three …

A Measure Of Expectancies For Alcohol Analgesia: Preliminary Factor Analysis, Reliability, And Validity, Lisa Renee Larowe

Dissertations - ALL

Rates of alcohol consumption are substantially higher among persons with pain, and recent research has focused on elucidating bidirectional pain-alcohol effects. Expectancies for alcohol analgesia could influence the degree to which alcohol confers acute pain-relieving effects, and may amplify the propensity to respond to pain with drinking behavior. However, no validated measures of expectancies for alcohol analgesia are available. The goal of this project was to examine psychometric properties of a measure of Expectancies for Alcohol Analgesia (EAA) across two samples (current alcohol users with and without chronic pain). Study 1 included 200 moderate-to-heavy drinkers with no current acute/chronic pain …

Coordination Geometries In Metallobundles Enforcing Oxidative And Hydrolytic Catalysis And Designing Biomaterials For Use As Antimicrobials, Jennifer Yoon

Dissertations - ALL

De novo protein design permits discovery of intricate folds and functions emulating natural enzymes in simpler, yet robust model constructs. Helical bundles serve as premier scaffolds to incorporate diverse reactivities from oxidative, reductive, to hydrolytic transformations observed in much grander O2-utilizing metalloproteins such as radical-generating ribonucleotide reductases and catalases. One notable family of de novo proteins is the Due Ferri or DF series of four-helix bundles providing a dinuclear site for metal incorporation and are amenable for tailoring active site reactivity. As reactive oxygen species and radical-based intermediates are prevalent and necessary for steering life-essential processes through reactive radicals stabilized …

Immigrant And U.S. Born Early Head Start Families: Exploring The Relationship Between Parenting Stress, Attachment Behaviors, Primary Caregiver Depressive Symptoms, And Parent-Child Attachment In A Nationally-Representative Sample, Shaelise Marie Tor

Dissertations - ALL

The current study sought to explore the relationship between parenting stress, attachment behaviors, primary caregiver depressive symptoms, and parent-child attachment in a nationally-representative Early Head Start sample of 2349 families. Additionally, the study explored whether there were differences between immigrant families and U.S. born families in terms of the main study variables. The study used a nationally representative secondary dataset, Baby FACES 2018 (Vogel et al., 2018). Data analysis was completed with PROCESS v. 3.3 (Hayes, 2018) in IBM SPSS v.26 (IBM, 2019). A series of mediation and moderated mediation models were tested aligning with each of the hypotheses. The …

Longitudinal Pre-Exposure Prophylaxis (Prep) Acceptability, Initiation And Adherence Among Criminal Justice-Involved Adults In The Usa: The Southern Prep Cohort Study (Specs) Protocol, Katherine Lemasters, Carrie B. Oser, Mariah Cowell, Katie Mollan, Kathryn Nowotny, Lauren Brinkley-Rubinstein

Sociology Faculty Publications

INTRODUCTION: HIV prevalence among criminal justice (CJ)-involved adults is five times higher than the general population. Following incarceration, CJ-involved individuals experience multilevel barriers to HIV prevention. Pre-exposure prophylaxis (PrEP) is a widely available, daily medication efficacious in preventing HIV. Little is known about PrEP knowledge, acceptability, initiation and sustained use among CJ-involved persons or about how these outcomes vary by multilevel factors. The Southern Pre-Exposure Prophylaxis Study (SPECS) will investigate barriers and facilitators for PrEP initiation and sustained use among CJ-involved adults, building a foundation for PrEP interventions for this underserved population.

METHODS AND ANALYSIS: SPECS uses a mixed-methods sequential …

Alteration Of The Canine Metabolome After A 3-Week Supplementation Of Cannabidiol (Cbd) Containing Treats: An Exploratory Study Of Healthy Animals, Elizabeth M. Morris, Susanna E. Kitts-Morgan, Dawn M. Spangler, Ibukun M. Ogunade, Kyle R. Mcleod, David L. Harmon

Animal and Food Sciences Faculty Publications

Despite the increased interest and widespread use of cannabidiol (CBD) in humans and companion animals, much remains to be learned about its effects on health and physiology. Metabolomics is a useful tool to evaluate changes in the health status of animals and to analyze metabolic alterations caused by diet, disease, or other factors. Thus, the purpose of this investigation was to evaluate the impact of CBD supplementation on the canine plasma metabolome. Sixteen dogs (18.2 ± 3.4 kg BW) were utilized in a completely randomized design with treatments consisting of control and 4.5 mg CBD/kg BW/d. After 21 d of …

High-Density Blood Transcriptomics Reveals Precision Immune Signatures Of Sars-Cov-2 Infection In Hospitalized Individuals, Jeremy W. Prokop, Nicholas L. Hartog, Dave Chesla, William Faber

University Faculty Publications and Creative Works

The immune response to COVID-19 infection is variable. How COVID-19 influences clinical outcomes in hospitalized patients needs to be understood through readily obtainable biological materials, such as blood. We hypothesized that a high-density analysis of host (and pathogen) blood RNA in hospitalized patients with SARS-CoV-2 would provide mechanistic insights into the heterogeneity of response amongst COVID-19 patients when combined with advanced multidimensional bioinformatics for RNA. We enrolled 36 hospitalized COVID-19 patients (11 died) and 15 controls, collecting 74 blood PAXgene RNA tubes at multiple timepoints, one early and in 23 patients after treatment with various therapies. Total RNAseq was performed …

The Effect Of Mindfulness On Adolescent Self-Compassion, Self-Regulation, And Stress: Exploring The Association Between Individual Factors And Markers Of Well-Being, Staceyann Reid

Dissertations - ALL

The purpose of this study was to explore the impact participating in a mindfulness-based intervention would have on various markers of well-being, including self-compassion, long-term self-regulation, and involuntary stress response for urban adolescents. This study evaluated how the individual factors of gender, grade level, and baseline extraversion/surgency are associated with the effect of the intervention on well-being outcomes. Participants in the final analytic sample included 1,809 students in ninth (316), eleventh (1258), and twelfth (235) grade from two public high schools in Philadelphia, Pennsylvania. The intervention was delivered by instructors trained in the Inner Strength Teen Program and classes took …

Effects Of Acid Deposition And Changing Climate On The Hydrochemistry And Critical Loads Of Watersheds In The Adirondack Region Of New York, Shuai Shao

Dissertations - ALL

Despite decreases in acidic deposition since the 1970s, the recovery of surface waters from acidification has been limited primarily due to the depletion of exchangeable base cations, net mineralization of organic sulfur and nitrogen and release of previously retained SO42- and NO3-, and increases in concentrations of naturally occurring organic acids from soil. The future recovery of stream chemistry from acidic deposition may be altered by projected increases in temperature and precipitation associated with a changing climate. The goals of this study were to conduct a modeling analysis of the response of soils and streams in the Adirondack Park, New …

N-Acetyl Cysteine Administration Affects Cerebral Blood Flow As Measured By Arterial Spin Labeling Mri In Patients With Multiple Sclerosis., Shiva Shahrampour, Justin Heholt, Andrew Wang, Faezeh Vedaei, Feroze B. Mohamed, Mahdi Alizadeh, Ze Wang, George Zabrecky, Nancy Wintering, Anthony J. Bazzan, Thomas P. Leist, Daniel A. Monti, Andrew B. Newberg

Department of Radiology Faculty Papers

Background: The purpose of this study was to explore if administration of N-acetyl-cysteine (NAC) in patients with multiple sclerosis (MS) resulted in altered cerebral blood flow (CBF) based on Arterial Spin Labeling (ASL) magnetic resonance imaging (MRI).

Methods: Twenty-three patients with mild to moderate MS, (17 relapsing remitting and 6 primary progressive) were randomized to either NAC plus standard of care (N = 11), or standard of care only (N = 12). The experimental group received NAC intravenously (50 mg/kg) once per week and orally (500mg 2x/day) the other six days. Patients in both groups were evaluated initially and after …

Yo Puedo: Para Empezar, Elizabeth Silvaggio-Adams, Rocío Vallejo-Alegre

Milne Open Textbooks

You have learned two words in a second language just by reading the title of the book. Think about that for a moment and reflect upon your prior foreign language experiences. Often, students enter language classes with previously acquired skills, be they from secondary school or another college. Many say, “I have studied Spanish for years and don’t know how to speak or write it,” while others are a bit anxious about taking a second language for the first time, but all are overwhelmed by the expensive textbooks and online packages that don’t seem to be practical or relevant. We …

Beetles Or Bureaucrats? Reconsidering The United States' Failure To Stop Dutch Elm Disease, Emily Bukowski

Dissertations - ALL

In this dissertation, I analyze the failure of the United States to address the Dutch elm disease (Ophiostoma ulmi) epidemic that affected American elm (Ulmus americana) across the country. The disease, a fungus carried by beetles between trees, was introduced in 1930 in New York City and slowly spread across the Northeast United States and beyond. A federal program to save the elm trees was in place from 1930-1952. I use archival documents to create a narrative describing the management of the disease by the Bureau of Entomology and Plant Quarantine, the division of the United States Department of Agriculture …

Seeding Sovereignty: Sensory Politics And Biodiversity In The Karen Diaspora, Terese Virginia Gagnon

Dissertations - ALL

This dissertation traces the sensory and political dimensions of Karen refugees' co-movements with their seeds, plants, and agricultural practices in exile. It also tentatively explores understandings of sovereignty beyond the frame of the Westphalian nation-state through engagements with seed and food sovereignty in three locations that complicate understandings of territorial sovereignty. In this dissertation I explore what I call "agricultural forgetting" and how it occurs for Karen refugees in the context of the camp. Agricultural forgetting, I suggest, is the process by which linkages between people and plants are broken generationally. Such forgetting occurs in especially sudden and forceful ways …

Development Of Computational Antibiotic Screening Platform Across Bacterial Outer Membrane Proteins, Yinghui Dai

Dissertations - ALL

Antibiotics are medicines used to treat bacterial infections by either killing bacteria or stopping them from reproducing. Throughout the use of antibiotics, bacteria has developed a variety of defense mechanisms against antibiotics and thus diminishing their effectiveness. Antibiotic resistance is a growing threat and becomes a global crisis as it is able to constantly evolve and rapidly spread. In the face of increasing bacterial resistance to all known antibiotics, there is an urgent need to accelerate the antibiotic discovery pipeline and discover new classes of antibiotics. A major bottleneck in the discovery of novel antibiotics is the limited permeability of …

A Small Molecule Induces Readthrough Of Cystic Fibrosis Cftr Nonsense Mutations, Public Relations

Browse All News

No abstract provided.

Thriving In Student Affairs Professionals: An Exploration Of Supporting Constructs, Shawn Brodie, Phillip Campbell, Gretchen Day Fricke, Kawanna Leggett, Norris Manning

Dissertations

Student affairs professionals provide vital services to college students while also facing various challenges that impact their ability to thrive at work. This study examined overall thriving, its constructs and a set of predictors that impact thriving in student affairs professionals. Seligman’s (PERMA) theory of thriving provided the conceptual foundation for this study. Understanding the constructs that support thriving for student affairs professionals will help institutional leaders and professional organizations develop work environments and strategies that promote thriving. A global pandemic occurred during the time of this research, allowing exploration of how COVID-19 impacted thriving. This study also included variables …

Reducing Covid-19 Quarantine With Sars-Cov-2 Testing: A Simulation Study, Patrick Yu, Peter G Matos, Alexander L Greninger, Julie Mccashin, Christopher I Amos

Faculty, Staff and Students Publications

OBJECTIVE: To evaluate the effectiveness of SARS-CoV-2 testing on shortening the duration of quarantines for COVID-19 and to identify the most effective choices of testing schedules.

DESIGN: We performed extensive simulations to evaluate the performance of quarantine strategies when one or more SARS-CoV-2 tests were administered during the quarantine. Simulations were based on statistical models for the transmissibility and viral loads of SARS-CoV-2 infections and the sensitivities of available testing methods. Sensitivity analyses were performed to evaluate the impact of perturbations in model assumptions on the outcomes of optimal strategies.

RESULTS: We found that SARS-CoV-2 testing can effectively reduce the …

Lipoprotein-Induced Increases In Cholesterol And 7-Ketocholesterol Result In Opposite Molecular-Scale Biophysical Effects On Membrane Structure, Manuela A.A. Ayee, Irena Levitan

Faculty Work Comprehensive List

Under hypercholesterolemic conditions, exposure of cells to lipoproteins results in a subtle membrane increase in the levels of cholesterol and 7-ketocholesterol, as compared to normal conditions. The effect of these physiologically relevant concentration increases on multicomponent bilayer membranes was investigated using coarse-grained molecular dynamics simulations. Significant changes in the structural and dynamic properties of the bilayer membranes resulted from these subtle increases in sterol levels, with both sterol species inducing decreases in the lateral area and inhibiting lateral diffusion to varying extents. Cholesterol and 7-ketocholesterol, however, exhibited opposite effects on lipid packing and orientation. The results from this study indicate …

Wheel Running Improves Fasting-Induced Ampk Signaling In Skeletal Muscle From Tumor-Bearing Mice, Dennis K. Fix, Brittany R. Counts, Ashley J. Smuder, Mark A. Sarzynski Ph.D., Faha, Facsm, Ho-Jin Koh, James A. Carson

Faculty Publications

Disruptions to muscle protein turnover and metabolic regulation contribute to muscle wasting during the progression of cancer cachexia. The initiation of cachexia is also associated with decreased physical activity. While chronic muscle AMPK activation occurs during cachexia progression in ApcMin/+ (MIN) mice, a preclinical cachexia model, the understanding of muscle AMPK’s role during cachexia initiation is incomplete. Therefore, we examined if voluntary wheel exercise could improve skeletal muscle AMPK signaling in pre-cachectic MIN mice. Next, we examined muscle AMPK’s role in aberrant catabolic signaling in response to a 12-h fast in mice initiating cachexia. Male C57BL/6 (B6: N …

Yo Puedo: Segundos Pasos, Elizabeth Silvaggio-Adams, Rocío Vallejo-Alegre

Milne Open Textbooks

Perhaps you remembered what the title of your book means from your previous experiences with Spanish. That is a great start! As you begin the equivalent of a second semester Spanish course with these materials, some of you might think about how long it has been since you studied Spanish while others may come to the class with some background knowledge. We want you to know this book has been designed with many types of learners in mind. Our goals were to address the need for students to achieve the ability to communicate in written and spoken form. We sought …

Decoding The Tunnel Behavior Of Damaraland Mole-Rats (Fukomys Damarensis), Cristina Aurora Rodriguez-Wagner

Electronic Theses and Dissertations Archive

Damaraland mole-rats, Fukomys damarensis, are an African rodent species that is one of two mammalian species considered eusocial. Damaraland mole-rats (DMR) live in large colonies comprised of a breeding pair and their non-reproductive offspring in underground tunnel systems. Many adaptations in DMR could be traced back to either their eusocial or subterranean lifestyle. DMR exhibit a behavior within their tunnels that consists of undulating their bodies, reminiscent of a break-dance move. The goal of this research was to characterize the properties of this enigmatic behavior. First, we investigated who exhibited the behavior and found that DMR break-dance regardless of age …

Spoken Word Learning In Children With Developmental Language Disorder Or Dyslexia, Suzanne M. Adlof, Lauren S. Baron, Bethany A. Bell, Joanna Scoggins

Faculty Publications

Purpose Word learning difficulties have been documented in multiple studies involving children with dyslexia and developmental language disorder (DLD; see also specific language impairment). However, no previous studies have directly contrasted word learning in these two frequently co-occurring disorders. We examined word learning in second-grade students with DLD-only and dyslexia-only as compared to each other, peers with both disorders (DLD + dyslexia), and peers with typical development. We hypothesized that children with dyslexia-only and DLD-only would show differences in word learning due to differences in their core language strengths and weaknesses. Method Children ( = 244) were taught eight novel …

Using Quantitative Stereology On High Resolution Sem Images To Estimate Diatom Percentages, Ariadna Covarrubias Ornelas

Dissertations and Theses

Diatoms are single-celled organisms of various shapes and sizes typically found in aquatic environments. When diatoms die, the organic material decomposes, and the outer skeletons (i.e., frustules) settle and accumulate as sedimentary deposits. These soils, called diatomaceous soils, exhibit nontraditional behavior since the diatom particles are typically hollow skeletons composed of amorphous silica with intricately patterned and abrasive surfaces. Recent studies have shown that diatomaceous soils are challenging geomaterials since even a small percentage of diatom particles will notably affect engineering behavior. Furthermore, laboratory studies on diatomaceous soil mixtures have demonstrated that many engineering soil properties depend on the percentage …

#Blackgirlmathmagic: A Mixed Methods Study Examining African American Girls In Standardized Mathematicstesting, Rakeema Thomas Toussaint

LSU Doctoral Dissertations

Black women have been making successful strides in mathematics for decades; however, they continue to be underrepresented in mathematics and other STEM fields. According to Young et al. (2017), Black girls and women perform lower in mathematics than all other racial gender groups except for Black males. Considering the stakes for Black girls and women in mathematics, this study sought to address this group's challenges early in their secondary education experiences, focusing on standardized testing.

The purpose of this explanatory-sequential mixed-methods study was to determine how different mathematics item types impacted the performance of African American girls, especially multiple-select multiple-choice …

Seasonal Variation In The Feeding Ecology Of Yellowfin Tuna (Thunnus Albacares) From The Northern Gulf Of Mexico, Mitchell Shay Lovell

LSU Master's Theses

Highly migratory fishes (e.g., tunas, billfishes, and sharks) play a significant role in the structure and function of open-ocean ecosystems and a better understanding of the food web dynamics that support their populations is essential to improve management and conservation. Here, I use complementary approaches (stomach contents, DNA barcoding, & stable isotopes) to examine seasonal variability in the feeding ecology of sub-adult (70 – 100 cm; n = 371) and adult (100 – 160 cm; n = 206) yellowfin tuna (Thunnus albacares) from the northern Gulf of Mexico over a one-year period (April 2019 – March 2020). Stomach …

Poster 04, Sukanya Pati

Drug Discovery and Development Colloquium

No abstract provided.

Poster 05, Robert Fogle

Drug Discovery and Development Colloquium

No abstract provided.

Poster 09, Narsimha Penthala

Drug Discovery and Development Colloquium

No abstract provided.

Poster 08, Seon Beom Kim

Drug Discovery and Development Colloquium

No abstract provided.