Digital Commons Network^™

Intersectionality And Feminist Pedagogy: Lessons From Teaching About Racism And Economic Inequity, Lisa J. Cunningham, Pao Lee Vue, Virginia B. Maier

The Seneca Falls Dialogues Journal

This paper utilizes Rochester, NY, as a case study to argue that approaching race intersectionally and across disciplines creates a stronger model of feminist pedagogy. It is based on our work in the classroom and on the Fisher Race Initiatives—a series of three interactive workshops we created on our campus to create change in the aftermath of the Michael Brown shooting in Ferguson, MO, and in the subsequent rise of the #BlackLivesMatter movement. Our goals were to promote dialogue on race, to expose participants to factual information on race, and to emphasize the intersectional causes of poverty in the Rochester …

Empowerment Through Dialogue: Women’S Experience With Division Of Labor As A Leisure Constraint In Family Life, Sarah Agate, Joel Agate

The Seneca Falls Dialogues Journal

Women in American society experience high levels of stress and the resultant physical and psychological challenges. While leisure is often seen as a context for stress relief, a variety of leisure constraints make it difficult for many women to have this experience. A focus group was conducted with five women who are mothers of young children to explore the division of labor in family travel. This paper reports on the experience of participant empowerment, which occurred through the dialogue that took place. Findings from this study have implications for those seeking to empower people who experience discrimination and marginalization in …

Appearance Discrimination: Lookism And The Cost To The American Woman, Alyssa Dana Dana Adomaitis, Rachel Raskin, Diana Saiki

The Seneca Falls Dialogues Journal

Lookism, or ranking an individual based on attractiveness, is a prevalent employment prejudice. Research has shown that looks influence salaries, career growth and even hiring (Warhurst, van den Broek, Hall, & Nickson, 2009). Because it is difficult to prove, there is no legislation that specifically addresses lookism. The current economy gives employers a vast selection of job applicants and candidates for open positions and “beauty premiums” (individuals considered above average with pretty faces) may have a better chance at being hired. According to a Newsweek national survey (2010) of 202 human resource staff which revealed that corporate hiring managers indicated …

Disrupting The Lean: Performing A 2016 Declaration Of Sentiments, Tambria Schroeder, Barbara Lesavoy, Melissa Brown, Brooke E. Love, Maggie Rosen, Brooke A. Ophardt, Audrey Lai

The Seneca Falls Dialogues Journal

Inspired by the spirit of disruption, this article narrates the making of a “2016 Declaration of Sentiments,” invented in a roundtable, “Disrupting the Lean: Performing a 2016 Declaration of Sentiments,” at the fifth Biennial Seneca Falls Dialogues (SFD). We open the essay with a brief theoretical overview that informs manifestos written in a feminist theory or senior seminar course that take up questions of gender equity, labor, and acts of resistance. We follow with excerpts from these manifestos as read in the roundtable, closing the essay with a “2016 Declaration of Sentiments,” collaboratively authored and recited by roundtable participants. Looking …

Investigating Local Adaptation To Hypoxia Stress In The Eastern Oyster Through Comparative Transcriptomics, Heather Nichole Smith

LSU Master's Theses

Climate change represents one of the most important challenges to biodiversity, therefore it is important to understand the mechanisms that allow species to respond to rapid environmental change. Here, we compared two populations of eastern oysters, Crassostrea virginica, from the Gulf of Mexico to study the mechanisms underlying hypoxia tolerance. Using a common garden experiment and comparative transcriptomics, we identified sets of genes involved in the hypoxia response and found differences in both the timing and baseline expression of hypoxia-responsive genes between tolerant and sensitive populations, consistent with a scenario of local adaptation. These genes include the signaling transcription factor …

Evaluation Of Cool-Season Annuals Effect On Soil Health In Warm-Season Perennial Pastures In Southestern Us., Paola C. Muela Negrete

LSU Master's Theses

Perennial grass crops represent approximately 8 million hectares of the land area of the humid lower southeastern United States. These forage crops receive high rates of fertilizer, especially nitrogen (N), and near monoculture remains have often been treated with repeated applications of herbicides. Pasture management is crucial to improve soil properties in pasturelands. Common pasture management practices include introducing cool-season multispecies in warm-season pasture systems and forage harvest frequency of pasture systems. It is known that cool-season multispecies in warm-season pasture systems ensure cattle feeding during winter season and have beneficial effects on soil microbial biomass, soil organic matter (SOM), …

Mobility And Development: Iranian Perspective, Hossein Badripour

IGC Proceedings (1977-2023)

No abstract provided.

Designing Land Taxes To Promote Conservation Through Use Of Rangelands: Bio‐Economic Modeling Of Farm Decision‐Making In Southern Namibia, Stephanie E. Domptail, Ernst‐August Nuppenau

IGC Proceedings (1977-2023)

No abstract provided.

Survey Of The Advanced Development Of Pastoral Education In Xilin Gol League, Yunhua Zhang

IGC Proceedings (1977-2023)

No abstract provided.

Protecting Hulun Buir Rangeland Requires Improving The Awareness Of The Importance Of The Ecological Status‐Based On An Investigation In Chen Baerhu Banner, Yunhua Zhang, Rui Liu

IGC Proceedings (1977-2023)

No abstract provided.

Improving The Policy Of Steppe Ecology Management And Promoting Sustainable Development In The Pasture Region: Based On Investigation In Inner Mongolia And Gansu Province, Yunhua Zhang

IGC Proceedings (1977-2023)

No abstract provided.

Nsf Grfp Information Session, Jason Hale

ORSP Presentations

NSF Graduate Research Fellowship Program (GRFP) Information Sessions

• Jason Hale, M.S., Director of Research Development, ORSP
• Robert Doerksen, Ph.D., Associate Dean of the Graduate School
• Vivian Ibrahim, Ph.D., Associate Professor of History; Director of the Office of National Scholarship Advisement

with Annette Kluck, Nikki Reinemann-Gross, Thomas Werfel, Cole Stevens, Courtney Roper, Rachel Greenspan, & Hoang V. Le

We Are...Marshall, July 21, 2021, Office Of Marshall University Communications

We Are ... Marshall: the Newsletter for Marshall University 1999-2023

No abstract provided.

Microvascular Sex- And Age- Dependent Phosphodiesterase Expression, Jianjie Wang, Murtaza M. Kazmi, Virginia H. Huxley

College of Health and Human Services

Objective: The cyclic nucleotide second messengers, cAMP and cGMP, are pivotal regulators of vascular functions; their cellular levels are tightly controlled by the cyclic nucleotide hydrolases, phosphodiesterases (PDE). Biologic sex and age are recognized as independent factors impacting the mechanisms mediating both vascular health and dysfunction. This study focused on microvessels isolated from male and female rats before (juvenile) and after (adult) sexual maturity under resting conditions. We tested the hypothesis that sexual dimorphism in microvascular PDE expression would be absent in juvenile rats, but would manifest in adult rats. Methods: Abdominal skeletal muscle arterioles and venules were isolated from …

Effect Of Biochanin A On The Rumen Microbial Community Of Holstein Steers Consuming A High Fiber Diet And Subjected To A Subacute Acidosis Challenge, Brittany E. Harlow, Michael D. Flythe, James L. Klotz, David L. Harmon, Glen E. Aiken

Animal and Food Sciences Faculty Publications

Subacute rumen acidosis (SARA) occurs when highly fermentable carbohydrates are introduced into the diet, decreasing pH and disturbing the microbial ecology of the rumen. Rumen amylolytic bacteria rapidly catabolize starch, fermentation acids accumulate in the rumen and reduce environmental pH. Historically, antibiotics (e.g., monensin, MON) have been used in the prevention and treatment of SARA. Biochanin A (BCA), an isoflavone produced by red clover (Trifolium pratense), mitigates changes associated with starch fermentation ex vivo. The objective of the study was to determine the effect of BCA on amylolytic bacteria and rumen pH during …

The Antimalarial Mmv688533 Provides Potential For Single-Dose Cures With A High Barrier To, James M. Murithi, Cécile Pascal, Jade Bath, Xavier Boulenc, Nina F. Gnädig, Charisse Flerida A. Pasaje, Kelly Rubiano, Tomas Yeo, Sachel Mok, Sylvie Klieber, Paul Desert, María Belén Jiménez-Díaz, Jutta Marfurt, Mélanie Rouillier, Mohammed H. Cherkaoui-Rbati, Nathalie Gobeau, Sergio Wittlin, Anne-Catrin Uhlemann, Ric N. Price, Grennady Wirjanata, Rintis Noviyanti, Patrick K. Tumwebaze, Roland A. Cooper, Philip J. Rosenthal, Laura M. Sanz, Francisco-Javier Gamo, Jayan Joseph, Shivendra Singh, Sridevi Bashyam, Jean Michel Augereau, Elie Giraud, Tanguy Bozec, Thierry Vermat, Gilles Tuffal, Jean-Michel Guillon, Jérôme Menegotto, Laurent Sallé, Guillaume Louit, Marie-José Cabanis, Marie Françoise Nicolas, Michel Doubovetzky, Rita Merino, Nadir Bessila, Iñigo Angulo-Barturen, Delphine Baud, Lidiya Bebrevska, Fanny Escudié, Jacquin C. Niles, Benjamin Blasco, Simon Campbell, Gilles Courtemanche, Laurent Fraisse, Alain Pellet, David A. Fidock, Didier Leroy

Natural Sciences and Mathematics | Faculty Scholarship

The emergence and spread of Plasmodium falciparum resistance to first-line antimalarials creates an imperative to identify and develop potent preclinical candidates with distinct modes of action. Here, we report the identification of MMV688533, an acylguanidine that was developed following a whole-cell screen with compounds known to hit high-value targets in human cells. MMV688533 displays fast parasite clearance in vitro and is not cross-resistant with known antimalarials. In a P. falciparum NSG mouse model, MMV688533 displays a long-lasting pharmacokinetic profile and excellent safety. Selection studies reveal a low propensity for resistance, with modest loss of potency mediated by point mutations in …

Dc-Derived Exosomes For Cancer Immunotherapy, Yi Yao, Chunmei Fu, Li Zhou, Qing-Sheng Mi, Aimin Jiang

Dermatology Articles

As the initiators of adaptive immune responses, DCs play a central role in regulating the balance between CD8 T cell immunity versus tolerance to tumor antigens. Exploiting their function to potentiate host anti-tumor immunity, DC-based vaccines have been one of most promising and widely used cancer immunotherapies. However, DC-based cancer vaccines have not achieved the promised success in clinical trials, with one of the major obstacles being tumor-mediated immunosuppression. A recent discovery on the critical role of type 1 conventional DCs (cDC1s) play in cross-priming tumor-specific CD8 T cells and determining the anti-tumor efficacy of cancer immunotherapies, however, has highlighted …

The Antimalarial Mmv688533 Provides Potential For Single-Dose Cures With A High Barrier To, James M. Murithi, Cécile Pascal, Jade Bath, Xavier Boulenc, Nina F. Gnädig, Charisse Flerida A. Pasaje, Kelly Rubiano, Tomas Yeo, Sachel Mok, Sylvie Klieber, Paul Desert, María Belén Jiménez-Díaz, Jutta Marfurt, Mélanie Rouillier, Mohammed H. Cherkaoui-Rbati, Nathalie Gobeau, Sergio Wittlin, Anne-Catrin Uhlemann, Ric N. Price, Grennady Wirjanata, Rintis Noviyanti, Patrick Tumwebaze, Roland A. Cooper, Philip J. Rosenthal, Laura M. Sanz, Francisco-Javier Gamo, Jayan Joseph, Shivendra Singh, Sridevi Bashyam, Jean Michel Augereau, Elie Giraud, Tanguy Bozec, Thierry Vermat, Gilles Tuffal, Jean-Michel Guillon, Jérôme Menegotto, Laurent Sallé, Guillaume Louit, Marie-José Cabanis, Marie Françoise Nicolas, Michel Doubovetzky, Rita Merino, Nadir Bessila, Iñigo Angulo-Barturen, Delphine Baud, Lidiya Bebrevska, Fanny Escudié, Jacquin C. Niles, Benjamin Blasco, Simon Campbell, Gilles Courtemanche, Laurent Fraisse, Alain Pellet, David A. Fidock, Didier Leroy

Natural Sciences and Mathematics | Faculty Scholarship

The emergence and spread of Plasmodium falciparum resistance to first-line antimalarials creates an imperative to identify and develop potent preclinical candidates with distinct modes of action. Here, we report the identification of MMV688533, an acylguanidine that was developed following a whole-cell screen with compounds known to hit high-value targets in human cells. MMV688533 displays fast parasite clearance in vitro and is not cross-resistant with known antimalarials. In a P. falciparum NSG mouse model, MMV688533 displays a long-lasting pharmacokinetic profile and excellent safety. Selection studies reveal a low propensity for resistance, with modest loss of potency mediated by point mutations in …

How Do Modifiable Risk Factors Impact The Progression Of Alzheimer’S Disease?, Shamso Jama

Theses and Graduate Projects

Alzheimer’s disease remains a significant health burden that affects millions in the United States. This research pursued to shed light on the modifiable risk factors and help individuals at high risk for Alzheimer’s disease minimize the chances of cognitive decline. A search of literature was conducted on databases such as PubMed, Google Scholar, and Medline. Randomized control trials, longitudinal studies, systematic reviews, and meta-analyses were identified and included in the paper. The modifiable risk factors that play a role in the onset and progression of Alzheimer’s disease include stress, inadequate physical exercise, lack of sleep hygiene, and lack of social …

Complexation Of Glycoalkaloid Α- Tomatine With Sterols And Its Potential Application As An Anti-Cancer Drug, Bishal Nepal

Dissertations

Glycoalkaloids (GAs) are secondary metabolites found mostly in higher plant species and some marine invertebrates. They are known to form complexes with 3β-hydroxy sterols such as cholesterol causing membrane disruption. So far the visual evidence showcasing the complexes formed between glycoalkaloids and sterols has been mainly restricted to some earlier studies using Brewster angle microscopy. This study aimed to develop a method for topographic and morphological analysis of sterol-glycoalkaloid complexes. Langmuir-Blodgett (LB) transfer of monolayers comprising of glycoalkaloid tomatine, sterols, and lipids in varying molar ratios onto mica followed by AFM examination was performed. The AFM method used required minimal …

A Comparison Of Heat Treatment-Induced Skeletal Muscle Adaptations Relative To Exercise Training, Jamie Puanani Brun Kaluhiokalani

Theses and Dissertations

In vitro and animal studies indicate that the response to heat stress is associated with beneficial adaptations that promote cell health and survival. Few studies to date have examined this finding in human subjects, and it is unclear how the adaptation compares in magnitude to exercise training. The purpose of this study was to investigate the skeletal muscle adaptations (namely mitochondrial biogenesis and capillarization) of 6 weeks of deep-muscle heat treatment relative to exercise training. We hypothesized that heat treatment (HT), applied through pulsed shortwave diathermy (2 hr, 3 days/week) over a 6-week intervention period would lead to increased mitochondrial …

Nesting Habits Of Cavity Nesting Bees And Wasps In Portland, Oregon, Stefanie Kay Steele

Dissertations and Theses

Native bees are threatened by habitat loss through urbanization, however, there is increasing interest in creating bee nesting habitat in urban areas. Few studies have determined what species are present in the region, or examined the role of nest height or cavity size in attracting the approximate one-third of native bees that nest in cavities. To determine what species were present, and whether they showed preferences for nesting at a certain height or cavity width, we set up artificial wooden cavity nest blocks across fourteen locations in the greater Portland, OR area. Wooden posts were erected with nest blocks at …

Gwu Summer Leadership Experience Gives First-Year Students Preview Of Campus Life, Office Of University Communications

Gardner-Webb NewsCenter Archive

The Gardner-Webb University Center for Personal and Professional Development welcomed 17 future leaders to campus recently for its Summer Leadership Experience. The three-day event for incoming first-year students is coordinated by Micah T. Martin, Center director, and Shea Mattingly, associate director.

Perception Versus Reality: A National Cohort Analysis Of The Surgery-First Approach For Resectable Pancreatic Cancer, John R. Bergquist, Cornelius A. Thiels, Christopher R. Shubert, Tommy Ivanics, Elizabeth B. Habermann, Santhi S. Vege, Travis E. Grotz, Sean P. Cleary, Rory L. Smoot, Michael L. Kendrick, David M. Nagorney, Mark J. Truty

Surgery Articles

INTRODUCTION: Although surgical resection is necessary, it is not sufficient for long-term survival in pancreatic ductal adenocarcinoma (PDAC). We sought to evaluate survival after up-front surgery (UFS) in anatomically resectable PDAC in the context of three critical factors: (A) margin status; (B) CA19-9; and (C) receipt of adjuvant chemotherapy.

METHODS: The National Cancer Data Base (2010-2015) was reviewed for clinically resectable (stage 0/I/II) PDAC patients. Surgical margins, pre-operative CA19-9, and receipt of adjuvant chemotherapy were evaluated. Patient overall survival was stratified based on these factors and their respective combinations. Outcomes after UFS were compared to equivalently staged patients after neoadjuvant …

Spatial Turnover Of Multiple Ecosystem Functions Is More Associated With Plant Than Soil Microbial Β-Diversity, Xin Jing, Case M. Prager, Elizabeth T. Borer, Nicholas J. Gotelli, Daniel S. Gruner, Jin-Sheng He, Kevin Kirkman, Andrew S. Macdougall, Rebecca L. Mcculley, Suzanne M. Prober, Eric W. Seabloom, Carly J. Stevens, Aimée T. Classen, Nathan J. Sanders

Plant and Soil Sciences Faculty Publications

Biodiversity—both above- and belowground—influences multiple functions in terrestrial ecosystems. Yet, it is unclear whether differences in above- and belowground species composition (β-diversity) are associated with differences in multiple ecosystem functions (e.g., spatial turnover in ecosystem function). Here, we partitioned the contributions of above- and belowground β-diversity and abiotic factors (geographic distance, differences in environments) on the spatial turnover of multiple grassland ecosystem functions. We compiled a dataset of plant and soil microbial communities and six indicators of grassland ecosystem functions (i.e., plant aboveground live biomass, plant nitrogen [N], plant phosphorus [P], root biomass, soil total N, and soil extractable P) …

The Informed Road Map To Prevention Of Alzheimer Disease: A Call To Arms, Eric Mcdade, Jorge J Llibre-Guerra, David M Holtzman, John C Morris, Randall J Bateman

2020-Current year OA Pubs

Alzheimer disease (AD) prevention trials hold the promise to delay or prevent cognitive decline and dementia onset by intervening before significant neuronal damage occurs. In recent years, the first AD prevention trials have launched and are yielding important findings on the biology of targeting asymptomatic AD pathology. However, there are limitations that impact the design of these prevention trials, including the translation of animal models that recapitulate key stages and multiple pathological aspects of the human disease, missing target validation in asymptomatic disease, uncertain causality of the association of pathophysiologic changes with cognitive and clinical symptoms, and limited biomarker validation …

Understanding The Interaction Between Habitat Use Of Feral Horses And The Abundance Of Greater Sage-Grouse In The Great Basin, Mikiah R. Carver

Theses and Dissertations

Environmental impacts of feral horses (Equus caballus) are a subject of conservation concern and controversial national policy. In North America, feral horses are considered an invasive species where they impact rangelands of the arid and semi-arid western United States. The greater sage-grouse (Centrocercus urophasianus) is a native sagebrush obligate bird species that relies on sagebrush habitats to sustain viable population levels. Recent literature suggests that feral horse presence can have a notable effect on the fitness of native and sagebrush obligate species throughout the arid and semi-arid western United States. The purpose of this thesis was to assess the potential …

Dan Farkas, Dan Farkas

Oral History

Dan Farkas has taught on the Pleasantville campus of Pace University since 1977.

Temporal Trends In Smoking And Nicotine Dependence In Relation To Co-Occurring Substance Use In The United States, 2005-2016, Yun Wang, Ying Liu, Mary Waldron, Alexandra N. Houston-Ludlam, Vivia V. Mccutcheon, Michael T. Lynskey, Pamela A. F. Madden, Kathleen K. Bucholz, Andrew C. Heath, Min Lian

Pharmacy Faculty Articles and Research

Background
Despite an overall decline in tobacco use in the United States, secular trends of smoking and nicotine dependence with co-occurring substance use are not well characterized.

Methods
We examined self-reported tobacco and other substance use in 22,245 participants age 21–59 in the United States from six waves of the National Health and Nutrition Examination Survey (NHANES). Using Joinpoint regression, we assessed secular trends of smoking and nicotine dependence as a function of co-occurring use of alcohol, prescription opioids, marijuana/hashish, cocaine/heroin/methamphetamine, or other injection drug use. Multivariable logistic regressions were fitted to identify the potential risk factors.

Results
During 2005–2016, …

Testing A Global Standard For Quantifying Species Recovery And Assessing Conservation Impact, Molly K. Grace, H Resit Akcakaya, Elizabeth L. Bennett, Thomas M. Brooks, Anna Heath, Simon Hedges, Craig Hilton-Taylor, Michael Hoffmann, Axel Hochkirch, Richard Jenkins, David A. Keith, Barney Long, David P. Mallon, Erik Meijaard, E J. Milner-Gulland, Jon Paul Rodriguez, P J. Stephenson, Simon N. Stuart, Richard P. Young, David Fairclough

Fisheries Research Articles

Recognizing the imperative to evaluate species recovery and conservation impact, in 2012 the International Union for Conservation of Nature (IUCN) called for development of a “Green List of Species” (now the IUCN Green Status of Species). A draft Green Status framework for assessing species’ progress toward recovery, published in 2018, proposed 2 separate but interlinked components: a standardized method (i.e., measurement against benchmarks of species’ viability, functionality, and preimpact distribution) to determine current species recovery status (herein species recovery score) and application of that method to estimate past and potential future impacts of conservation based on 4 metrics ( …