Digital Commons Network^™

Existentially Guilty: Where Do I Go From Here?, Devontae Wilson

Master of Arts in English Plan II Graduate Projects

Teachers, students, parents, and even politicians have been forced to confront the by-products of not having difficult conversations about race and class. Political pundits are using this moment in history sparked by recorded injustice and the publicized murders of unarmed black people at the hands of law enforcement to demonize Critical Race Theory (CRT), a framework created to analyze how the law is racialized. This portfolio is largely a result of Dr. Rudine Sims-Bishop’s “Mirrors, Windows, and Sliding Glass Doors” and contextualizing it through my personal experience as a classroom teacher, as a black man in a majority white, female …

Scenario Planning For Resilient Agricultural Systems: A Process For Engaging Controversy, Crystal A. Powers, Tyler Williams, Rick R. Stowell

Journal of Extension

Resiliency to weather extremes is already a part of farming in the North Plains, but now climate change is adding new uncertainties. Engaging farmers on this often controversial topic can be challenging given the wide range of beliefs farmers hold about climate change. Scenario planning provides a framework for Extension and agricultural system stakeholders to come together using the latest climate science to discover robust adaptive management options, prioritize Extension programming needs, and provide an open forum for starting the discussion.

Alcohol Use And History Of Traumatic Brain Injury In College Students: An Analysis Of Neuropsychological And Behavioral Factors, Jessie Tibbs

Department of Psychology: Dissertations, Theses, and Student Research

Approximately 69,000,000 individuals sustain TBIs each year worldwide. Alcohol use is a known risk factor for TBI. Nearly 50% of individuals with TBI endorse binge drinking, alcohol-related negative consequences, or meet criteria for AUDs. One of the most pressing issues within the alcohol-TBI literature is predicting post-TBI alcohol-related problems, as this results in poorer recovery, rehabilitation, and functioning. Evidence for TBIs causing post-injury alcohol use in those without pre-injury problematic alcohol use is mixed; not all TBI survivors experience alcohol-related problems post-injury. Evidence is mounting that one of the most robust predictors of post-injury alcohol problems is childhood or adolescent …

More Evidence That Magnitude Interference In Temporal Reproduction Results From Memory, Not Clock, Interference, Steven A. Masi

Seton Hall University Dissertations and Theses (ETDs)

Past research has found that errors made when acting on magnitude information is influenced by irrelevant magnitude information that is simultaneously present in the environment. This study investigated the processing stage during which the interference occurs. Each participant completed 80 test trials in stimulus (encoding stimulus) appeared on the computer screen for one of four lengths of time and then disappeared. After which, participants held down the computer spacebar for either the full or half the time that the encoding stimulus was on the screen. In both conditions, a second stimulus (reproduction stimulus) was displayed as the participants held down …

3d Single Cell Scale Anatomical Map Of Sex-Dependent Variability Of The Rat Intrinsic Cardiac Nervous System., Clara Leung, Shaina Robbins, Alison Moss, Maci Heal, Mahyar Osanlouy, Richard Christie, Navid Farahani, Corey Monteith, Jin Chen, Peter Hunter, Susan Tappan, Rajanikanth Vadigepalli, Zixi Jack Cheng, James S. Schwaber

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

We developed and analyzed a single cell scale anatomical map of the rat intrinsic cardiac nervous system (ICNS) across four male and three female hearts. We find the ICNS has a reliable structural organizational plan across individuals that provide the foundation for further analyses of the ICNS in cardiac function and disease. The distribution of the ICNS was evaluated by 3D visualization and data-driven clustering. The pattern, distribution, and clustering of ICNS neurons across all male and female rat hearts is highly conserved, demonstrating a coherent organizational plan where distinct clusters of neurons are consistently localized. Female hearts had fewer …

Freedom Of Speech At Ursinus College, Benjamin Henwood

Business and Economics Summer Fellows

Freedom of speech is a hot topic issue on many college campuses across the United States. My research project’s goal is to find out how our community at Ursinus College feels about freedom of speech. My project is going to explore how well Ursinus holds itself to its standards of free and open inquiry and how the students on campus feel about free and open inquiry. In order to understand how the community feels about free speech on our campus, we borrowed a survey from the Foundation of Individual Rights in Education and distributed it to roughly half of the …

Rnase Κ Promotes Robust Pirna Production By Generating 2',3'-Cyclic Phosphate-Containing Precursors, Megumi Shigematsu, Takuya Kawamura, Keisuke Morichika, Natsuko Izumi, Takashi Kiuchi, Shozo Honda, Venetia Pliatsika, Ryuma Matsubara, Isidore Rigoutsos, Susumu Katsuma, Yukihide Tomari, Yohei Kirino

Computational Medicine Center Faculty Papers

In animal germlines, PIWI proteins and the associated PIWI-interacting RNAs (piRNAs) protect genome integrity by silencing transposons. Here we report the extensive sequence and quantitative correlations between 2′,3′-cyclic phosphate-containing RNAs (cP-RNAs), identified using cP-RNA-seq, and piRNAs in the Bombyx germ cell line and mouse testes. The cP-RNAs containing 5′-phosphate (P-cP-RNAs) identified by P-cP-RNA-seq harbor highly consistent 5′-end positions as the piRNAs and are loaded onto PIWI protein, suggesting their direct utilization as piRNA precursors. We identified Bombyx RNase Kappa (BmRNase κ) as a mitochondria-associated endoribonuclease which produces cP-RNAs during piRNA biogenesis. BmRNase κ-depletion elevated transposon levels and disrupted a piRNA-mediated …

Genomic Variability In The Survival Motor Neuron Genes (Smn1 And Smn2): Implications For Spinal Muscular Atrophy Phenotype And Therapeutics Development, Matthew E R Butchbach

Department of Pediatrics Faculty Papers

Spinal muscular atrophy (SMA) is a leading genetic cause of infant death worldwide that is characterized by loss of spinal motor neurons leading to muscle weakness and atrophy. SMA results from the loss of survival motor neuron 1 (SMN1) gene but retention of its paralog SMN2. The copy numbers of SMN1 and SMN2 are variable within the human population with SMN2 copy number inversely correlating with SMA severity. Current therapeutic options for SMA focus on increasing SMN2 expression and alternative splicing so as to increase the amount of SMN protein. Recent work has demonstrated that not all …

Knowing Our People To Serve Our People, Alessandra Jimenez

MEDI 9331 Scholarly Activities Clinical Years

Health disparities continue to persist in the United States despite the work clinicians and professionals have undertaken to close the gaps. Nowhere in the recent past have these disparities been more evident than during the US response to the COVID-19 pandemic. The differential outcome of patients was stark within marginalized communities accounting for greater burden due to the health risks that were already incurred. Additionally, data provided from the health care system’s front lines were incomplete resulting in slower and less robust interventions than what were needed. This paper seeks to outline first steps that can be taken to ensure …

Relation Between Academic Advisor And Cohort Support With Well-Being In Graduate Students, Morgan Delong

Masters Theses, 2020-current

Well-being issues like the limitations of typical treatment protocols and common mitigating factors for mental health problems for graduate students, specifically the importance of therapeutic lifestyle changes (TLCs) were explored. The current study aims to determine if TLCs, individual engagement in the TLCs as well as support of them by mentors and peers, predict overall well-being, satisfaction with the graduate program, and job stress in masters’ students. This study was conducted during COVID-19 which is a limitation.

Throwing Pebbles While Waiting: An Autoethnographic Exploration Of Mental Health And Colonialism, Kelly Limes Taylor, Rita Sørly, Bengt Karlsson

The Qualitative Report

In this article, three scholars jointly investigate questions of Western colonization and mental health. While their areas of interest and experience vary, the authors discuss oppression as a common thread connecting their ideas about mental health and its medicalization. In line with Toyosaki et al. (2009), the researchers did a community autoethnography, performing written dialogue as a dynamic research method. Using a sequential model, Kelly Limes Taylor wrote about her experience, passed it on to Rita Sørly and Bengt Karlsson. Karlsson added his story to the previous writing, and he passed it on to Sørly for further addition of stories. …

Experiences Of Iranian Women With Prenatal Diagnosis Of Fetal Abnormalities: A Qualitative Study, Fahimeh Ranjbar, Fatemeh Oskouie, Shahrzad Hashemi Dizaji, Maryam Gharacheh

The Qualitative Report

Women are more likely to be diagnosed with congenital anomalies due to advances in new technologies in medical science. Following prenatal diagnosis of fetal abnormalities, women may be forced to make decisions about whether to continue a pregnancy with fetal abnormalities. This can be a dilemma for the women. The aim of the study was to explore women’s experiences of prenatal diagnosis of fetal abnormalities. A qualitative study was conducted in a referral women’s hospital in Tehran, Iran in 2018. Participants were a purposeful sample of 15 women with prenatal diagnosis of fetal abnormalities. Data were collected by individual, in-depth …

An Assessment Of The Factors Influencing The Prediction Accuracy Of Genomic Prediction Models Across Multiple Environments, Sarah Widener, George Graef, Alexander E. Lipka, Diego Jarquin

Department of Agronomy and Horticulture: Faculty Publications

The effects of climate change create formidable challenges for breeders striving to produce sufficient food quantities in rapidly changing environments. It is therefore critical to investigate the ability of multi-environment genomic prediction (GP) models to predict genomic estimated breeding values (GEBVs) in extreme environments. Exploration of the impact of training set composition on the accuracy of such GEBVs is also essential. Accordingly, we examined the influence of the number of training environments and the use of environmental covariates (ECs) in GS models on four subsets of n = 500 lines of the soybean nested association mapping (SoyNAM) panel grown in …

3 Faculty Elevated To Distinguished, University Professorships, Haley Herfurth

Browse All News

No abstract provided.

Veganic Agriculture In The United States: Opportunities For Research, Outreach, And Education, Alisha Utter, Mona Seymour

Journal of Extension

A growing number of farmers are excluding animal inputs from crop production, an approach commonly referred to as veganic or stockfree organic agriculture. This research-based article discusses the soil health and fertility strategies reported by a sample of U.S. veganic farmers. These approaches may be relevant beyond the veganic community to farmers seeking innovative methods for produce safety and nutrient cycling. Agricultural outreach professionals (AOPs), including Extension personnel, play a critical role in supporting veganic practices by serving as cross-pollinators between farmers and research institutions. Thus, the article endeavors to expand AOP familiarity with veganic practices and benefits.

Defining Acquired Mutations In Healthy Breast Tissue And Their Association With Breast Cancer Risk Factors And Breast Cancer, Kevin Nead Md, Christina Mcdowell, Raven J. Hollis

Summer Experience 2021

No abstract provided.

The Winning Narrative: The Social Genesis Of Pilgrimage Sites, Stephen F. Haller, Dane Munro Km

International Journal of Religious Tourism and Pilgrimage

While pilgrimage sites may be sparked by historical events, their meaning is created by their accompanying narratives. A pilgrimage site becomes sacred to visitors not merely because of scripture, or supposed religious facts, but also because of social and psychological contexts. It is their winning narrative that supplies meaning and a framework for understanding. Without such narratives, it is conceivable that some pilgrimage sites would not have gained their enduring popularity and international appeal. This article not only describes a few instances of such sites rising to fame, but also the philosophy behind a winning narrative.

The idea that narrative …

The Fatty Acid Profile Of Traditional Home‐Made Kurut In Xinjiang Pastoral Regions, Yimamu Aibibula, Masaaki Hanada, M. Hirata, M. Renaguli, M. Goto

IGC Proceedings (1977-2023)

No abstract provided.

Multiple‐Use Grasslands: Integrating Forage, Biofuel, And Carbon/Phosphorus Sinks, James P. Muir, B. Lambert, G. W. Evers, T. J. Butler, K. F. Bronson, L. Stanley‐Stevens, R. D. Wittie

IGC Proceedings (1977-2023)

No abstract provided.

Producing Biofuels With Alternative Fertilizers: A Comparison Of Two Promising Species, Mari‐Vaughn V. Johnson, James R. Kiniry

IGC Proceedings (1977-2023)

No abstract provided.

Biorenewable Energy: New Opportunities For Grassland Agriculture, Kenneth J. Moore, Steven L. Fales, Emily A. Heaton

IGC Proceedings (1977-2023)

No abstract provided.

Multiple Use Management On Canadian Publicly Managed Rangeland, B. Kirychuk, R. Gaube, S. Kushreshtha, G. Pearson

IGC Proceedings (1977-2023)

No abstract provided.

The Action Is Listening: Undergraduate Women Of Color & Sense Of Belonging At Usd, Mayzong Lee

M.A. in Higher Education Leadership: Action Research Projects

At the intersection of gender and race, women of color (WOC) often lack holistic support in navigating their undergraduate experience at the University of San Diego (USD). My purpose in this action research was to understand how Women of Color define, experience, and navigate their sense of academic, social, and cultural belonging at USD beyond the data. Consisting of three cycles, this research asked participants to define each sense of belonging followed by an individual interview to share how they have experienced their own definition of belonging at USD. The last cycle of this research was an opportunity for participants …

On The Conventional Definition Of Path-Specific Effects - Fully Mediated Interaction With Multiple Ordered Mediators, An-Shun Tai, Le-Hsuan Liao, Sheng-Hsuan Lin

Harvard University Biostatistics Working Paper Series

Path-specific effects (PSEs) are a critical measure for assessing mediation in the presence of multiple mediators. However, the conventional definition of PSEs has generated controversy because it often causes misinterpretation of the results of multiple mediator analysis. For in-depth analysis of this issue, we propose the concept of decomposing fully mediated interaction (FMI) from the average causal effect. We show that FMI misclassification is the main cause of PSE misinterpretation. Two strategies for specifying FMI are proposed: isolating FMI and reclassifying FMI. The choice of strategy depends on the objective. Isolating FMI is the superior strategy when the main objective …

07-22-2021 Madge Lenz Jordan Scholars Named At Swosu, Southwestern Oklahoma State University

THE BARK ARCHIVE 2021

No abstract provided.

Medical School Watercooler Newsletter - July 22, 2021, Lindsey Lyle

Watercooler Newsletter

This is the July 22, 2021 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents include:

• Faculty Spotlight: Walker Plash, M.D.
• Student-Run Free Clinic seeks volunteer preceptors
• USA COM graduate researcher examines relationship between bacteria and their vectors
• Meet a Med Student: Alana Fortune

Linguicide In The Digital Age: Problems And Possible Solutions, Michael Adelson

French Summer Fellows

This project aims to assess the relative success of revitalization efforts for seven languages: Welsh, Scottish Gaelic, Irish, Hopi, Navajo, Breton, and Occitan. The success of linguistic revitalization is determined through comparative analysis of minority languages in the United States, the United Kingdom, Ireland, and France as seen through each country’s history, melting pot experiences, traditions, language protection laws, education system, in addition to the differing levels of diffusion via the Internet. A key point of analysis is the strength of language protection laws in the United States, United Kingdom, Ireland, and France. Language is the most primordial expression of …

Enhancing Civic Engagement Through Leadership Education, Lori E. Kniffin Ph.D., Sonalini Sapra

Leadership Faculty Publications

Many civic engagement courses within higher education require students to work with community members to make progress on complex problems, which in itself can comprise leadership practice. Yet, there is little evidence that leadership development is strategically incorporated into such civic engagement courses in general. The authors taught eight leadership sessions over two semesters in the Principled Problem Solving Scholars program at Guilford College. The study discussed in this article examined the perceived impact of a leadership curriculum on the personal leadership practices and the civic engagement of 14 undergraduate students. The authors present their findings in the context of …

Myeloid Cell Mediated Immune Suppression In Pancreatic Cancer, Samantha B. Kemp, Marina Pasca Di Magliano, Howard C. Crawford

Research Administration Articles

Pancreatic ductal adenocarcinoma (PDA), the most common pancreatic cancer, is a nearly-universally lethal malignancy. PDA is characterized by extensive infiltration of immunosuppressive myeloid cells, including tumor-associated macrophages (TAMs) and myeloid-derived suppressor cells (MDSCs). Myeloid cells in the tumor microenvironment (TME) inhibit cytotoxic T cell responses promoting carcinogenesis. Immune checkpoint therapy has not been effective in PDA, most likely due to this robust immune suppression, making it critical to elucidate mechanisms behind this phenomenon. Here, we review myeloid cell infiltration and cellular crosstalk in PDA progression and highlight current therapeutic approaches to target myeloid cell-driven immune suppression.

Potentiation Of Acetylcholine-Induced Relaxation Of Aorta In Male Uc Davis Type 2 Diabetes Mellitus (Ucd-T2dm) Rats: Sex-Specific Responses, Farjana Akther, Md Rahatullah Razan, Sonali Shaligram, James L. Graham, Kimber L. Stanhope, Kaitlin N. Allen, José Pablo Vázquez-Medina, Peter J. Havel, Roshanak Rahimian

School of Pharmacy Faculty Articles

Previous reports suggest that diabetes may differentially affect the vascular beds of females and males. The objectives of this study were to examine whether there were (1) sex differences in aortic function and (2) alterations in the relative contribution of endothelium-derived relaxing factors in modulating aortic reactivity in UC Davis Type 2 Diabetes Mellitus (UCD-T2DM) rats. Endothelium-dependent vasorelaxation (EDV) in response to acetylcholine (ACh) was measured in aortic rings before and after exposure to pharmacological inhibitors. Relaxation responses to sodium nitroprusside were assessed in endothelium-denuded rings. Moreover, contractile responses to phenylephrine (PE) were measured before and after incubation of aortic …