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2021

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Chronic Voluntary Alcohol Drinking Causes Anxiety-Like Behavior, Thiamine Deficiency, And Brain Damage Of Female Crossed High Alcohol Preferring Mice, Hong Xu, Hui Li, Dexiang Liu, Wen Wen, Mei Xu, Jacqueline A. Frank, Jing Chen, Haining Zhu, Nicholas J. Grahame, Jia Luo Mar 2021

Chronic Voluntary Alcohol Drinking Causes Anxiety-Like Behavior, Thiamine Deficiency, And Brain Damage Of Female Crossed High Alcohol Preferring Mice, Hong Xu, Hui Li, Dexiang Liu, Wen Wen, Mei Xu, Jacqueline A. Frank, Jing Chen, Haining Zhu, Nicholas J. Grahame, Jia Luo

Molecular and Cellular Biochemistry Faculty Publications

The central nervous system is vulnerable to chronic alcohol abuse, and alcohol dependence is a chronically relapsing disorder which causes a variety of physical and mental disorders. Appropriate animal models are important for investigating the underlying cellular and molecular mechanisms. The crossed High Alcohol Preferring mice prefer alcohol to water when given free access. In the present study, we used female cHAP mice as a model of chronic voluntary drinking to evaluate the effects of alcohol on neurobehavioral and neuropathological changes. The female cHAP mice had free-choice access to 10% ethanol and water, while control mice had access to water …


Quiz Bowl And Speaker Highlight Double Virtual Oxford Science Cafe, Edwin B. Smith Mar 2021

Quiz Bowl And Speaker Highlight Double Virtual Oxford Science Cafe, Edwin B. Smith

University of Mississippi News

Audience participation event, lecture scheduled for March 16 and 25 via Zoom


Examining Differences In Achievement Of Physical Activity Best Practices Between Urban And Rural Child Care Facilities By Age, Danae Dinkel, John Rech, Yage Guo, Matthew R. Bice, Emily Hulse, Donnia Behrends, Christina Burger, Dipti Dev Mar 2021

Examining Differences In Achievement Of Physical Activity Best Practices Between Urban And Rural Child Care Facilities By Age, Danae Dinkel, John Rech, Yage Guo, Matthew R. Bice, Emily Hulse, Donnia Behrends, Christina Burger, Dipti Dev

Journal Articles

Go Nutrition and Physical activity Self Assessment in Child Care (NAP SACC) is an evidence based intervention developed to positively impact childhood obesity in early childhood education (ECE) facilities. One focus of Go NAP SACC is the development of physical activity best practices. However, little research has examined differences in achievement of best practices based on age of child and geographic location. The purpose of this study was to examine differences in the achievement of physical activity best practices between urban and rural childcare facilities by age-specific recommendations (infants, toddlers, and preschoolers) and in the overall physical activity environment. Urban …


Research On Aging During The Venezuelan Humanitarian Crisis: The Experience Of The Maracaibo Aging Study, Gladys E. Maestre, Rosa V. Pirela, Carmen Paz, Jesus D. Melgarejo, Luis J. Mena, Carlos A. Chavez, Reinier Leendertz, Michele Petitto, Egle Silva, Gustavo E. Calmon Mar 2021

Research On Aging During The Venezuelan Humanitarian Crisis: The Experience Of The Maracaibo Aging Study, Gladys E. Maestre, Rosa V. Pirela, Carmen Paz, Jesus D. Melgarejo, Luis J. Mena, Carlos A. Chavez, Reinier Leendertz, Michele Petitto, Egle Silva, Gustavo E. Calmon

School of Medicine Publications

Background

Venezuela is in the throes of a complex humanitarian crisis that is one of the worst in decades to impact any country outside of wartime. This case analysis describes the challenges faced by the ongoing Maracaibo Aging Study (MAS) during the deteriorating conditions in Venezuela. When the MAS began in 1997, it focused on memory-related disorders. Since then, strategic planning and proactive community participation allowed us to anticipate and address logistical, funding, and ethical challenges, and facilitated the enrollment and retention of more than 2500 subjects over 55 years of age. All participants, who are residents of the city …


Hidden Sugar And Its Bitter Obstacles For The Wellbeing Of Consumers, Ai Nhan Ngo Mar 2021

Hidden Sugar And Its Bitter Obstacles For The Wellbeing Of Consumers, Ai Nhan Ngo

Markets, Globalization & Development Review

This research paper explores issues pertaining to, and raises awareness about, high sugar intake among consumers, which causes several consequential health risks. The paper also points out various obstacles preventing consumers from reducing their high sugar consumption. These obstacles come from policymakers, policy influencers, the sugar industry, the food industry, and consumers themselves. For some obstacles, involvement of multiple parties was found. The research also discusses several possible solutions for improving a healthy consumption environment for consumer wellbeing.


The Complex Challenges Of Protecting Consumers, Deniz Atik, Nikhilesh Dholakia Mar 2021

The Complex Challenges Of Protecting Consumers, Deniz Atik, Nikhilesh Dholakia

Markets, Globalization & Development Review

No abstract provided.


The Utah Statesman, March 8, 2021, Utah State University Mar 2021

The Utah Statesman, March 8, 2021, Utah State University

The Utah Statesman

Weekly student newspaper of Utah State University in Logan.


Catholic Terminal Sedation-A New Framework For Providing Terminal Palliative Sedation As A Requirement In Catholic Healthcare Organizations, Noah Dimas Mar 2021

Catholic Terminal Sedation-A New Framework For Providing Terminal Palliative Sedation As A Requirement In Catholic Healthcare Organizations, Noah Dimas

Graduate Student Research Symposium

The present attitudes surrounding death and dying in the United States have been trending toward the acceptance of so-called “Assisted Death” interventions at the end-of-life (EoL), specifically Physician-Assisted Suicide. The acceptance of these interventions is rooted in the notion of autonomy within the American culture of medicine that generally states a patient is allowed to request whatever medical interventions they wish. As such, legislative bodies around the United States have begun to legalize Assisted Death in response to the regularly cited desire to die peacefully and without pain from an expected terminal illness. However, for Catholic healthcare organizations, there is …


Financial Inclusion And Banking Regulation: The Role Of Proportionality, Kern Alexander Mar 2021

Financial Inclusion And Banking Regulation: The Role Of Proportionality, Kern Alexander

Law and Contemporary Problems

No abstract provided.


Factors Associated With Chronic Kidney Disease Of Non-Traditional Causes Among Children In Guatemala, Alejandro Cerón, Brooke M. Ramay, Luis Pablo Méndez-Alburez, Randall Lou-Meda Mar 2021

Factors Associated With Chronic Kidney Disease Of Non-Traditional Causes Among Children In Guatemala, Alejandro Cerón, Brooke M. Ramay, Luis Pablo Méndez-Alburez, Randall Lou-Meda

Anthropology: Faculty Scholarship

Objective. To identify factors associated with chronic kidney disease of non-traditional causes among children in Guatemala. Methods. A cross-sectional survey was conducted. The study population was all pediatric patients with stage 5 chronic kidney disease active in FUNDANIER’s pediatric nephrology unit (N = 156). Simple random sampling led to a total of 100 participants. Data collection consisted of a questionnaire addressing individual and household characteristics, access and utilization of health care, and place of residence when the disease began. Chronic kidney disease etiology was obtained from medical records. Municipality-level secondary data were collected. Descriptive statistics were estimated. Logistic regression was …


Isometric Exercises And Stretching Warm-Up Program For University String Musicians: An Intervention Study, Emma Porter Mar 2021

Isometric Exercises And Stretching Warm-Up Program For University String Musicians: An Intervention Study, Emma Porter

Honors Program: Senior Projects (Public)

In this study, the purpose of this investigation was to find the effects of reducing pain through combining isometric and stretching warm-up exercises for stringed instrument musicians. In Lee’s et al. (2013) study, it showed that about 75 % of musicians have work-related musculoskeletal disorders and experience pain because of playing. In this study, they also saw that string players have the highest prevalence of both musculoskeletal disorders and pain while playing (Lee et al., 2013). In Nawrocka’s et al. (2014) journal article, the study showed the correlation of more pain in musicians that did not meet the recommended criteria …


Parents’ Perception Of Their Preschool Children’S Weight Status And Diet Quality: How Accurate It Is?, Taraneh Hazhin Mar 2021

Parents’ Perception Of Their Preschool Children’S Weight Status And Diet Quality: How Accurate It Is?, Taraneh Hazhin

Seton Hall University Dissertations and Theses (ETDs)

Childhood obesity is a major public health problem. Parents often have an inaccurate perception of their child’s weight status and diet quality. The purpose of this study was to assess the accuracy of parents’ perception of their 3-5 years old children’s weight status and diet quality; and to explore if there was a relationship between parental weight perception, parental diet perception, and children’s diet quality. A cross-sectional survey design was used to collect data from parents of healthy 3-5 years old preschool children (n=333) through convenient sampling method. Parents’ perception of their preschool children’s weight status was measured using a …


Silicate-Solubilizing Bacteria In Louisiana Soils: Identification, Profiling, And Functions In Crop Production, Jayvee A. Cruz Mar 2021

Silicate-Solubilizing Bacteria In Louisiana Soils: Identification, Profiling, And Functions In Crop Production, Jayvee A. Cruz

LSU Doctoral Dissertations

Studies were conducted to determine the potential of silicate-solubilizing bacteria (SSB) as biostimulant in Louisiana rice (Oryza sativa L.) production systems. Isolation and profiling of SSB in Louisiana soils; evaluation on its effects on the silicon (Si) uptake and productivity of rice using various carriers derived from slag, rice hull, and sugarcane (Officinarum spp.) bagasse; and development of a feasible approach of incorporating SSB to the rice production system were conducted. Results showed that numerous bacteria isolated from Louisiana soils can solubilize silicate and produce multiple plant growth-promoting compounds. These potential SSBs were identified into four genera: Aeromonas, …


The 6-Week Effects Of Hiit On Biomarkers Of Tissue And Oxidative Damage In Wistar Rats Previously Supplemented With Pyridoxine, Jéssica Danielle Matos, Felipe J. Aidar, Dihogo Gama De Matos, José Uilien De Oliveira, Ailton Santos Sena Júnior, Jymmys Lopes Dos Santos, Anderson Carlos Marçal, Silvan Silva De Araújo Mar 2021

The 6-Week Effects Of Hiit On Biomarkers Of Tissue And Oxidative Damage In Wistar Rats Previously Supplemented With Pyridoxine, Jéssica Danielle Matos, Felipe J. Aidar, Dihogo Gama De Matos, José Uilien De Oliveira, Ailton Santos Sena Júnior, Jymmys Lopes Dos Santos, Anderson Carlos Marçal, Silvan Silva De Araújo

International Journal of Exercise Science

International Journal of Exercise Science 14(7): 369-381, 2021. We aimed to analyze the effects of long high-intensity interval training (HIIT) associated with pyridoxin supplementation on tissue and oxidative injury markers in animals. Male Wistar rats were divided into three groups (n = 8): sedentary (GS), HIIT (GH), and HIIT + pyridoxine (GHP). The HIIT comprised 18 sessions of 7 repetitions of 2min × 2min rest, 3 times per week. Pyridoxine was administered to the GHP group 1h before the exercise. The Thiobarbituric acid reactive substances (TBARS) and sulfhydryl group (SH) were analyzed as markers of oxidative stress and CK, LDH, …


Skilled Throwing Performance: A Test Of The Optimal Theory, Jacquelyn V.L. Sertic, Jason M. Avedesian, James W. Navalta Mar 2021

Skilled Throwing Performance: A Test Of The Optimal Theory, Jacquelyn V.L. Sertic, Jason M. Avedesian, James W. Navalta

International Journal of Exercise Science

International Journal of Exercise Science 14(5): 358-368, 2021. The OPTIMAL theory of motor learning postulates that autonomy support (AS), enhanced expectancies (EE), and an external focus of attention (EF) facilitate improved motor learning and performance. However, its applicability to elite-level throwing athletes has not been investigated by previous literature. The primary purpose of this study was to investigate the successive implementation of AS, EE, and EF factors on overhand throwing performance in elite collegiate softball athletes (14.44 ± 2.75 years of softball experience). The secondary purpose was to determine whether self-efficacy beliefs would be augmented by factor manipulation. Twenty-four participants …


Technology Usage In The Restaurant Industry, Julia Ransom Mar 2021

Technology Usage In The Restaurant Industry, Julia Ransom

Hospitality Graduate Student Scholarship

Walking into a restaurant ten years into the future, you may experience utter silence. You will most likely approach a kiosk, put in your order, swipe a card or tap a card, and wait patiently for your order without having said a single word to a person in the building. Off you go, lunch in hand, back to your busy life with a bag full of food to get you through the day. Or perhaps you go to a drive through, scan your phone, have someone hand you your food, and drive away - only because you pre-ordered everything and …


The Relationship Between New Graduate Registered Nurse Knowledge, Experiences, Attitudes, And Age Bias Toward The Older Adult, Michelle Fox Mar 2021

The Relationship Between New Graduate Registered Nurse Knowledge, Experiences, Attitudes, And Age Bias Toward The Older Adult, Michelle Fox

USF Tampa Graduate Theses and Dissertations

There had been a lack of research on the relationship between a new graduate Registered Nurses’ knowledge, experiences, attitudes, and age bias toward older adults. The purpose of this study was to investigate whether there was a relationship between new graduate Registered Nurses’ knowledge, experiences, attitudes, and age bias toward older adults.

The researcher used correlational, non-experimental, quantitative design for this study. The instruments used in this study were the Facts on Aging Quiz, the Kogan Attitude Toward Old People scale, and a demographic questionnaire. Descriptive statistics were used to analyze the demographic data and correlation coefficients were used to …


Impact Of A Summer Nutrition And Physical Activity Intervention To Attenuate Obesity In Urban African-American Youth, Jermaine B. Mitchell, Antonio J. Gardner, Zachary Wahl-Alexander, Ben Schwamberger, Douglas Craddock Jr., Carol N. Agomo, Myia C. Lang Mar 2021

Impact Of A Summer Nutrition And Physical Activity Intervention To Attenuate Obesity In Urban African-American Youth, Jermaine B. Mitchell, Antonio J. Gardner, Zachary Wahl-Alexander, Ben Schwamberger, Douglas Craddock Jr., Carol N. Agomo, Myia C. Lang

International Journal of Aquatic Research and Education

Improved eating behaviors and daily participation in physical activity such as swimming might abate the likelihood of African American youth becoming obese. Yet many African American youth neither consume the recommended daily servings of nutritious foods nor know how to swim. The purpose of this study was to investigate the impact of a culturally tailored multicomponent summer intervention to reduce obesity and unintentional drownings among underserved African American youth. Children (n = 145) participated in a three-hour, community-based intervention for four weeks. Measures of children’s attitudes perceived behavioral control, and subjective norms toward swimming, nutrition, and physical fitness were …


Cardiovascular Disease Risk, Awareness, And Treatment In People With Epilepsy, Samuel W Terman, Carole E Aubert, Chloe E Hill, Jeremy Skvarce, James F Burke, Scott Mintzer Mar 2021

Cardiovascular Disease Risk, Awareness, And Treatment In People With Epilepsy, Samuel W Terman, Carole E Aubert, Chloe E Hill, Jeremy Skvarce, James F Burke, Scott Mintzer

Department of Neurology Faculty Papers

OBJECTIVE: To evaluate whether cardiovascular risk, risk awareness, and guideline concordant treatment differ in individuals with versus without epilepsy.

METHODS: This was a retrospective cross-sectional study using the National Health and Nutrition Examination Survey. We included participants ≥18 years for 2013-2018. We classified participants as having epilepsy if reporting ≥1 medication treating seizures. We calculated 10-year atherosclerotic cardiovascular disease (ASCVD) risk using the revised pooled cohort equation. We compared unadjusted and adjusted risk for participants with versus without epilepsy. We then assessed hypertension and diabetes disease awareness and control, plus statin guideline-concordance. We assessed mediators for both ASCVD risk and …


Development And Feasibility Testing Of A Play-Based Psychosocial Intervention For Reduced Patient Stress In A Pediatric Care Setting: Experiences From Pakistan, Muneera A. Rasheed, Vardah Bharuchi, Waliyah Mughis, Ayesha Hussain Mar 2021

Development And Feasibility Testing Of A Play-Based Psychosocial Intervention For Reduced Patient Stress In A Pediatric Care Setting: Experiences From Pakistan, Muneera A. Rasheed, Vardah Bharuchi, Waliyah Mughis, Ayesha Hussain

Department of Paediatrics and Child Health

Background: Hospitalization can be a source of great stress for children and their families. In high-income countries, there are specialized staff to help children cope using different techniques including play. However, it is a major challenge in low and middle-income countries (LMIC) due to financial constraints and untrained human resource. The objective of study was to develop and test the feasibility and acceptance of a psychology trainee-delivered model postulated on employing play as a means of enhancing child-parent interactions leading to reduced stress during hospitalization.
Methods: This study was conducted in the paediatric ward of a tertiary care private hospital …


Adolescent Health In The Sustainable Development Goal Era: Are We Aligned For Multisectoral Action?, Asha George, Tanya Jacobs, Rajani Ved, Troy Jacobs, Kumanan Rasanathan, Shehla Zaidi Mar 2021

Adolescent Health In The Sustainable Development Goal Era: Are We Aligned For Multisectoral Action?, Asha George, Tanya Jacobs, Rajani Ved, Troy Jacobs, Kumanan Rasanathan, Shehla Zaidi

Community Health Sciences

Adolescents are an increasing proportion of low and middle-income country populations. Their coming of age is foundational for health behaviour, as well as social and productive citizenship. We mapped intervention areas for adolescent sexual and reproductive health, including HIV, mental health and violence prevention to sectors responsible for them using a framework that highlights settings, roles and alignment. Out of 11 intervention areas, health is the lead actor for one, and a possible lead actor for two other interventions depending on the implementation context. All other interventions take place outside of the health sector, with the health sector playing a …


Judicial Review Of National Regulations Under Smcra And Holmes Limestone Co. V. Andrus: Is The District Court For The District Of Columbia The Only Proper Forum?, John Cato Fogle Iii Mar 2021

Judicial Review Of National Regulations Under Smcra And Holmes Limestone Co. V. Andrus: Is The District Court For The District Of Columbia The Only Proper Forum?, John Cato Fogle Iii

Journal of Natural Resources & Environmental Law

No abstract provided.


Statutory Time Limitations On The Availability Of Judicial Review Of Regulations Under Smcra, Jack C. Bender Mar 2021

Statutory Time Limitations On The Availability Of Judicial Review Of Regulations Under Smcra, Jack C. Bender

Journal of Natural Resources & Environmental Law

No abstract provided.


Acute Effects Of High-Intensity Resistance Exercise On Cognitive Function, John Paul V. Anders, William J. Kraemer, Robert U. Newton, Emily M. Post, Lydia K. Caldwell, Matthew K. Beeler, William H. Dupont, Emily R. Martini, Jeff S. Volek, Keijo Hakkinen, Carl M. Maresh, Scott M. Hayes Mar 2021

Acute Effects Of High-Intensity Resistance Exercise On Cognitive Function, John Paul V. Anders, William J. Kraemer, Robert U. Newton, Emily M. Post, Lydia K. Caldwell, Matthew K. Beeler, William H. Dupont, Emily R. Martini, Jeff S. Volek, Keijo Hakkinen, Carl M. Maresh, Scott M. Hayes

Health and Sport Sciences Faculty Scholarship

The purpose of the present study was to examine the influence of an acute bout of high-intensity resistance exercise on measures of cognitive function. Ten men (Mean ± SD: age = 24.4 ± 3.2 yrs; body mass = 85.7 ± 11.8 kg; height = 1.78 ± 0.08 m; 1 repetition maximum (1RM) = 139.0 ± 24.1 kg) gave informed consent and performed a high-intensity 6 sets of 10 repetitions of barbell back squat exercise at 80% 1RM with 2 minutes rest between sets. The Automated Neuropsychological Assessment Metrics (ANAM) was completed to assess various cognitive domains during the familiarization period, …


Growth Of Preterm Very Low Birth Weight Infants Discharged With Weight Of Less Than 1500grams, Yaser Abdallah, Flavia Namiiro, Jolly Nankunda, Jamiru Mugalu, Yvonne Vaucher Mar 2021

Growth Of Preterm Very Low Birth Weight Infants Discharged With Weight Of Less Than 1500grams, Yaser Abdallah, Flavia Namiiro, Jolly Nankunda, Jamiru Mugalu, Yvonne Vaucher

Faculty of Health Sciences, East Africa

Early discharge of preterm very low birth weight (VLBW) infants is at times inevitable in low resource settings. The implication of such practice on the growth of this high-risk population is not known. We conducted a retrospective chart review to describe the growth of preterm VLBW infants discharged with a weight of less than 1500 g.

Objectives

To describe the growth of discharged preterm VLBW infants over the first 12 weeks.

Method

Between June 2013 and January 2014; 164 discharged preterm VLBW infants were followed up for 3 months. Among the survivors (132), we identified 111 infant records for this …


Maternal Vitamin And Mineral Supplementation And Rate Of Maternal Weight Gain Affects Placental Expression Of Energy Metabolism And Transport-Related Genes, Wellison J. S. Diniz, Lawrence P. Reynolds, Pawel P. Borowicz, Alison K. Ward, Kevin K. Sedivec, Kacie L. Mccarthy, Cierrah J. Kassetas, Friederike Baumgaertner, James D. Kirsch, Sheri T. Dorsam, Tammi L. Neville, J. Chris Forcherio, Ronald R. Scott, Joel S. Caton, Carl R. Dahlen Mar 2021

Maternal Vitamin And Mineral Supplementation And Rate Of Maternal Weight Gain Affects Placental Expression Of Energy Metabolism And Transport-Related Genes, Wellison J. S. Diniz, Lawrence P. Reynolds, Pawel P. Borowicz, Alison K. Ward, Kevin K. Sedivec, Kacie L. Mccarthy, Cierrah J. Kassetas, Friederike Baumgaertner, James D. Kirsch, Sheri T. Dorsam, Tammi L. Neville, J. Chris Forcherio, Ronald R. Scott, Joel S. Caton, Carl R. Dahlen

Department of Animal Science: Faculty Publications

Maternal nutrients are essential for proper fetal and placental development and function. However, the effects of vitamin and mineral supplementation under two rates of maternal weight gain on placental genome-wide gene expression have not been investigated so far. Furthermore, biological processes and pathways in the placenta that act in response to early maternal nutrition are yet to be elucidated. Herein, we examined the impact of maternal vitamin and mineral supplementation (from pre-breeding to day 83 post-breeding) and two rates of gain during the first 83 days of pregnancy on the gene expression of placental caruncles (CAR; maternal placenta) and cotyledons …


Advertising During The Covid-19 Global Pandemic: The Rise Of Influencer Marketing Strategies In A Recession, Bre Tenhulzen Mar 2021

Advertising During The Covid-19 Global Pandemic: The Rise Of Influencer Marketing Strategies In A Recession, Bre Tenhulzen

Honors Program: Senior Projects (Public)

The COVID-19 pandemic reached the United States in January of 2020 and has since impacted nearly all industries, including advertising. Consumers, the guiding factors for all advertising strategies, faced drastic lifestyle changes and behavior shifts which sent current strategies askew. The virus has created insurmountable unknowns, thus advertising and marketing experts must rely on historical and recent data to develop strategies for brands forging ahead. COVID-19 is the first global crisis in the age of social media which has both helped and hindered communication during the crisis. Additionally, emerging influencer marketing strategies are proving more effective than ever as brands …


Marker Placement Reliability And Objectivity For Biomechanical Cohort Study: Healthy Aging In Industrial Environment (Haie—Program 4), Jan Malus, Jiri Skypala, Julia Freedman Silvernail, Jaroslav Uchytil, Joseph Hamill, Tomas Barot, Daniel Jandacka Mar 2021

Marker Placement Reliability And Objectivity For Biomechanical Cohort Study: Healthy Aging In Industrial Environment (Haie—Program 4), Jan Malus, Jiri Skypala, Julia Freedman Silvernail, Jaroslav Uchytil, Joseph Hamill, Tomas Barot, Daniel Jandacka

Kinesiology and Nutrition Sciences Faculty Research

In large cohort studies, due to the time-consuming nature of the measurement of movement biomechanics, more than one evaluator needs to be involved. This may increase the potential occurrence of error due to inaccurate positioning of markers to the anatomical locations. The pur-pose of this study was to determine the reliability and objectivity of lower limb segments length by multiple evaluators in a large cohort study concerning healthy aging in an industrial environment. A total of eight evaluators performed marker placements on five participants on three different days. Evaluators placed markers bilaterally on specific anatomical locations of the pelvis, thigh, …


Sitosterolemia: Twenty Years Of Discovery Of The Function Of Abcg5abcg8, Kori Williams, Allison Segard, Gregory A. Graf Mar 2021

Sitosterolemia: Twenty Years Of Discovery Of The Function Of Abcg5abcg8, Kori Williams, Allison Segard, Gregory A. Graf

Pharmaceutical Sciences Faculty Publications

Sitosterolemia is a lipid disorder characterized by the accumulation of dietary xenosterols in plasma and tissues caused by mutations in either ABCG5 or ABCG8. ABCG5 ABCG8 encodes a pair of ABC half transporters that form a heterodimer (G5G8), which then traffics to the surface of hepatocytes and enterocytes and promotes the secretion of cholesterol and xenosterols into the bile and the intestinal lumen. We review the literature from the initial description of the disease, the discovery of its genetic basis, current therapy, and what has been learned from animal, cellular, and molecular investigations of the transporter in the twenty …


Effects Of Neonatal Nutrition Interventions On Neonatal Mortality And Child Health And Development Outcomes: A Systematic Review, Aamer Imdad, Faseeha Rehman, Evans Davis, Deepika Ranjit, Gamael S. S. Surin, Suzanna L. Attia, Sarah Lawler, Abigail A. Smith, Zulfiqar A. Bhutta Mar 2021

Effects Of Neonatal Nutrition Interventions On Neonatal Mortality And Child Health And Development Outcomes: A Systematic Review, Aamer Imdad, Faseeha Rehman, Evans Davis, Deepika Ranjit, Gamael S. S. Surin, Suzanna L. Attia, Sarah Lawler, Abigail A. Smith, Zulfiqar A. Bhutta

Pediatrics Faculty Publications

Background
The last two decades have seen a significant decrease in mortality for children < 5 years of age in low and middle‐income countries (LMICs); however, neonatal (age, 0–28 days) mortality has not decreased at the same rate. We assessed three neonatal nutritional interventions that have the potential of reducing morbidity and mortality during infancy in LMICs.

Objectives
To determine the efficacy and effectiveness of synthetic vitamin A, dextrose oral gel, and probiotic supplementation during the neonatal period.

Search Methods
We conducted electronic searches for relevant studies on the following databases: PubMed, CINAHL, LILACS, SCOPUS, and CENTRAL, Cochrane Central Register for Controlled Trials, up to November 27, 2019.

Selection Criteria
We aimed to include randomized and quasi‐experimental studies. The target population was neonates in LMICs. The interventions included synthetic vitamin A supplementation, oral dextrose gel supplementation, and probiotic supplementation during the neonatal period. …