Digital Commons Network^™

Design And Construction Of A Biosafety Level 3 Autopsy Laboratory, Kurt B. Nolte, Timothy B. Muller, Adam M. Denmark, Ron Burstein, Yvonne A. Villalobos

Pathology Research and Scholarship

Context.—: Autopsy pathologists, including medical examiners, provide valuable public health support for infectious disease deaths through surveillance for deaths of public health concern including emerging infections, identifying causative organisms for unexplained deaths, and providing insights into the pathology and pathogenesis of novel or unusual infections. However, autopsy poses biosafety risks to workers within and outside the laboratory. The highest rates of laboratory-acquired infections occur in autopsy workers.

Objective.—: To design and construct an appropriately biosafe autopsy laboratory.

Design.—: We conducted a biosafety risk assessment for autopsy workers using the process developed by the US Centers for Disease Control and Prevention …

Agent Orange-Induced Anaplastic Large-Cell Lymphoma (Alcl) With Cutaneous Involvement, Morgan Lorio, Brandon Lewis, John Hoy, Matthew Yeager

ETSU Faculty Works

Anaplastic large-cell lymphoma (ALCL) is a CD30 + lymphoproliferative disorder that may manifest with skin involvement.1 We present a rare case of Agent Orange-induced ALCL with cutaneous involvement of the hand, surgical excision, and follow-up treatment.

Examining Factors Associated With Bcg And Poliomyelitis Vaccination Coverage In Tanzanian And Kenyan Children Aged 12 To 23 Months Using Dhs Surveys, Ognyan Simeonov

Independent Study Project (ISP) Collection

The rapid spread of infectious diseases in eastern Africa has made vaccination a major health factor in the region. This study aims to evaluate the factors affecting vaccination coverage with the BCG and Poliomyelitis vaccines in Tanzanian and Kenyan children aged 12 to 23 months. In May 2021, we collected data from the Demographic and Health Surveys (DHS) from 2014-2016 for Kenya and Tanzania and evaluated how different variables such as the sex of the child, maternal age, maternal educational level, availability of health facilities, access to electricity in the household, and birth order affect the vaccination coverage. We used …

Pedagogic Recontextualization In Health Science Education During A Global Pandemic: Faculty Perspectives On Instructional Adaptations, Kara R. De La Fosse

Education Doctorate Dissertations

This qualitative study explored Health Science faculty navigating learning during a global pandemic. Data collection sources for the study comprised individual interviews, individual online questionnaires, and a focus group. The study produced four emergent themes from data analysis of individual interviews, online questionnaires, and the focus group: Faculty Flexibility with Responding to Virtual Instructional Delivery, Shift from Didactic to Conceptual Contextual Learning, Shift in Assessment of Skills and Competency, and Faculty Creativity in Changing the State of Practice Through Course Design. Conclusions from the study established changing pedagogy from a teacher-focused to student-focused approach and employing creativity were paramount with …

Primary Care Providers’ Comfort With Utilization Of Genetics In Practice, Taylor Mackenzie Kupneski

Theses and Dissertations

Primary care providers (PCPs) are often the first opportunity for individuals at risk for a genetic condition to be identified and they must care for patients with known genetic conditions. However, PCPs lag behind other providers in incorporating genetics into their practice. This study aimed to understand which genetics related concepts/topics PCPs (1) find relevant to practice, (2) are currently comfortable utilizing in practice, and (3) desire further education on. A mixed methods survey was sent to internists, family medicine providers, OBGYNs, pediatricians and geriatrics providers in South Carolina via email to assess this information. This included physicians, nurse practitioners, …

A Spatial Risk Prediction Model For Drug Overdose, Parisa Bozorgi

Theses and Dissertations

Drug overdose is a leading cause of unintentional death in the United States and has contributed significantly to a decline in life expectancy from 2015 to 2018. Overdose deaths, especially from opioids, have also been recognized in recent years as a significant public health issue. To address this public health problem, this study sought to identify neighborhood-level (e.g., block group) factors associated with drug overdose and develop a spatial model using machine learning (ML) algorithms to predict the likelihood or risk of drug overdoses across South Carolina. This study included block group level socio-demographic factors and drug use variables which …

A General Pathological Outlook Of Covid-19, Shadman Shaikh

Honor’s College Freeman Research Journal

The COVID-19 pandemic has been expressed as one of the world’s most fatal pandemics in recent human history, and with good reason. At the time of this writing, over 125 million global cases have been confirmed, with a death toll rate sitting at 2.5 million. From the moment the pandemic was announced globally, the international scientific community sought out to analyze more about the virus in the hopes to find a cure. It should be imperative to analyze this virus in all aspects, including recent treatment efforts. Doing so will allow us to not only understand as to how this …

Special Research Edition, Lori Gwyn, Cj Smith, Jennifer Cook-Johns

The Source

Emily Bedea became SWOSU’s third grand prize winner in the 26 years of Research Day at the Capital.

Delivering Nutrition Interventions To Women And Children In Conflict Settings: A Systematic Review, Shailja Shah, Zahra Ali Padhani, Daina Als, Mariella Munyuzangabo, Michelle F. Gaffey, Wardah Ahmed, Fahad J. Siddiqui, Sarah Meteke, Jai K. Das, Zulfiqar Ahmed Bhutta

Woman and Child Health

Background: Low/middle-income countries (LMICs) face triple burden of malnutrition associated with infectious diseases, and non-communicable diseases. This review aims to synthesise the available data on the delivery, coverage, and effectiveness of the nutrition programmes for conflict affected women and children living in LMICs.
Methods: We searched MEDLINE, Embase, CINAHL, and PsycINFO databases and grey literature using terms related to conflict, population, and nutrition. We searched studies on women and children receiving nutrition-specific interventions during or within five years of a conflict in LMICs. We extracted information on population, intervention, and delivery characteristics, as well as delivery barriers and facilitators. Data …

Department Of Economics Newsletter, V25, Spring 2021, University Of Northern Iowa. Department Of Economics.

Department of Economics Newsletter

Inside this Issue:

--- Message from Shar
--- Open Access Week
--- Virtual Jepson Forum Discusses Health Inequality
--- Lawrence M. Jepson Student Awards
--- 2020-2021 Scholarship Winners
--- Difficulties in Decision Making During the Pandemic
--- The Labor Market Impact of COVID-19
--- GDP and Jobs Recovering from COVID-19
--- Ryan Rudderham Joins Economics Faculty
--- The Transition from Administration to Faculty
--- The Retirement of KenMcCormick
--- Bülent Uyar Retires (mostly)
--- Faculty and Staff Updates

Making The Comeback From Combat: An Analysis Of The Effectiveness Of Occupational Therapy For Combat Veterans, Julia A. Hickey

Honors Theses

Combat veterans have been found to experience difficulties with community reintegration after coming back from their deployments. Many of them experience physical and mental injuries from their deployment, such as mild traumatic brain injury, post-traumatic stress disorder, and amputations. Combat veterans not having effective treatment for these injuries can contribute to issues with community reintegration. These issues can consist of marital and financial problems, problems with alcohol or substance abuse, homelessness, and motor vehicle accidents. The Department of Veterans Affairs and the United States military have put forth efforts with improving community reintegration for combat veterans; one of those efforts …

Evaluation Of The Biosynthesized Silver Nanoparticles’’ Effects On Biofilm Formation, Nehia Hussein, Mina M. Khadum

Journal of Applied Sciences and Nanotechnology

In this study 50 isolates were obtained from the Baghdad teaching city medicine laboratories, from wounds and burns. Isolates were identified exercise VITEK 2 system (Biomerieux). Streptococcus pyogenes isolate was used to create the biosynthesize of silver nanoparticles’’ against some pathogenic microbes such as Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli, and Candida albicans. Evaluation of the effect of the created biosynthesis silver nanoparticles’’ (AgNPs) by Streptococcus pyogenes on the biofilm formation by various human pathogenic bacteria.  Biosynthesis of AgNPs was characterized by ultraviolet-visible absorption spectroscopy, the observation of color change of the experimental samples in the presence of 1 mM …

Impact Of Follow Up Blood Cultures On Outcomes Of Patients With Community-Onset Gram-Negative Bloodstream Infection, Rajiv Amipara, Hana Rac Winders, Julie Ann Justo, P Brandon Bookstaver, Joseph Kohn, Majdi N. Al-Hasan

Faculty Publications

Background: The role of follow up blood cultures (FUBC) in the management of gram-negative bloodstream infection (GN-BSI) remains controversial. This retrospective cohort study examines the association between obtaining FUBC and mortality in GN-BSI.

Methods: Hospitalized adults with community-onset GN-BSI at Prisma Health-Midlands hospitals in South Carolina, USA from January 1, 2010 to June 30, 2015 were identified. Patients who died or were discharged from hospital within 72 h were excluded to minimize impact of survival and selection biases on results, respectively. Multivariate Cox proportional hazards regression was used to examine association between obtaining FUBC and 28-day all-cause mortality after adjustment …

The Effects Of Patient-Physician Interaction Time On Overall Visit Satisfaction And Prevention Of Physician Burnout, Miranda Sheridan

Senior Honors Theses

With an increasingly commercialized healthcare setting, today’s physicians are often forced to reduce their patient examination times drastically. There has also been a greater shift in the administration of primary care to allied health professionals such as physician assistants and nurse practitioners. However, these changes may not be sustainable in the long-term. This study investigates the relationship between time spent with a physician (M.D. or D.O.) during an examination and overall patient satisfaction. Moreover, mental health concerns, namely burnout, have become more prevalent among physicians. Studying this under the lens of accelerated modern medicine could help shed light on strategies …

The Benefits And Barriers To Receiving Medication-Assisted Treatment Inside And Outside Of Prison And Its Implications For Louisiana, Jennifer Johnson

Honors Capstones

No abstract provided.

Parasite Prevalence In Marsh Rice Rats (Oryzomys Palustris) On Sites Affected By The 2010 Deepwater Horizon Oil Spill, Layni Leblanc

Honors Capstones

No abstract provided.

The Synchrony Of Pathogen Events, Tivon Eugene

Honors Capstones

No abstract provided.

Evaluation Of Changes In Drug Susceptibility And Population Genetic Structure In Haemonchus Contortus Following Worm Replacement As A Means To Reverse The Impact Of Multiple-Anthelmintic Resistance On A Sheep Farm, Melissa M. George, Adriano F. Vatta, Sue B. Howell, Bob E. Storey, Ciaran J. Mccoy, Adrian J. Wolstenholme, Elizabeth M. Redman, John S. Gilleard, Ray M. Kaplan

Faculty Publications

A population of Haemonchus contortus that was highly resistant to benzimidazoles and avermectin/milbemycins with a subpopulation that was resistant to levamisole, was replaced with a susceptible laboratory isolate of H. contortus in a flock of sheep. The anthelmintic susceptibility and population genetics of the newly established population were evaluated for 3.5 years using in vivo, in vitro, and molecular methods. Successful replacement of the resistant population with a susceptible population was confirmed using phenotypic and genotypic measurements; larval development assay indicated full anthelmintic susceptibility; albendazole treatment yielded 98.7% fecal egg count reduction; pyrosequence genotyping of single nucleotide polymorphisms in positions …

Hydrothermal Synthesis And Structural Investigation Of A Crystalline Uranyl Borosilicate, Kristen A. Pace, Vladislav V. Klepov, Mark D. Smith, Travis Williams, Gregory Morrison, Jochen A. Lauterbach, Scott T. Misture, Hans Conrad Zur Loye

Faculty Publications

The relevance of multidimensional and porous crystalline materials to nuclear waste reme-diation and storage applications has motivated exploratory research focused on materials discovery of compounds, such as actinide mixed-oxoanion phases, which exhibit rich structural chemistry. The novel phase K1.8 Na1.2 [(UO2)BSi4 O12 ] has been synthesized using hydrothermal methods, rep-resenting the first example of a uranyl borosilicate. The three-dimensional structure crystallizes in the orthorhombic space group Cmce with lattice parameters a = 15.5471(19) Å, b = 14.3403(17) Å, c = 11.7315(15) Å, and V = 2615.5(6) Å3, and is composed of UO6 octahedra linked by [BSi4 O12 ]5− chains to …

Weathering The Pandemic: Dying Old At A Young Age From Pre-Existing Racist Conditions, Arline T. Geronimus

Washington and Lee Journal of Civil Rights and Social Justice

Mainstream social epidemiology now acknowledges the contributions of interpersonal racism, racialized stress, and implicit bias to population health inequity. It also increasingly recognizes that current and historical racist policies place barriers in the way of healthy lifestyles by institutionalizing food deserts, housing decay, and austerity urbanism. Essential as these developments are, they only skim the surface of how insidiously structural racism establishes and reproduces population health inequity. I coined the term “weathering” to describe the effects of sustained cultural oppression upon the body. Weathering expands on the more conventional “social determinants of health” approach to understand the contextually fluctuating and …

Empathy’S Promise And Limits For Those Disproportionately Harmed By The Covid-19 Pandemic, Theresa Glennon

Washington and Lee Journal of Civil Rights and Social Justice

Structural race, ethnicity, and class disparities in the United States concentrated and intensified the health, economic, and psychological impact of COVID-19 for certain populations. Those same structural disparities and the belief system that maintains them may also account for the weak policy response that left the United States with high rates of infection and death, economic devastation of individuals, families, and small businesses, and psychological distress. A more equal society with a stronger pre-pandemic safety net may have prevented or eased the disproportionate hardship and avoided the drama and cliffhanging. Or the shock of a pandemic and likelihood of extreme …

Past The Tipping Point, But With Hope Of Return: How Creating A Geoengineering Compulsory Licensing Scheme Can Incentivize Innovation, Brooke Wilson

Washington and Lee Journal of Civil Rights and Social Justice

This Note explores the patenting of geoengineering technologies and issues arising from the early stages of this high-risk, high-reward technology. This Note focuses on one possible solution to solving the issues surrounding the patenting of geoengineering technology: Creating a specialized compulsory licensing scheme.

Nebline, April 2021

NEBLINE Newsletter Archive from Nebraska Extension in Lancaster County

Experiential Learning Teaches Skills and More

DIY FitBall: A Fun Fitness Activity

Recipe of the Month

Get Ready to Control Pine Tip Blight

Garden Guide

2021 Prennial Plant of the Year

Naturally Occurring Elements in Groundwater, Part 2 of a Series: Iron and Manganese

No Bull! Examine Your Sires’ Breeding Soundness

Inspiring Rich Conversations through Questions by Sarah Roberts

Become a Community Scientist by Kait Chapman

Hearto f 4-H Volunteer Award: James Blake

4-H Announcements for 4-H'ers and Volunteers

Watch Chicks Hatch on Egg Cam

4-H Achievement Celebration

Extension Calendar

2021 Weed Awareness

Controlling and Managing Phragmites

Take 2, Two …

B-Cell-Intrinsic Mhcii Signaling Shapes Microbiota Composition, Sergei Alexeev

Senior Theses

Recent studies demonstrate that immunoglobulin A (IgA) is critical for limiting chronic inflammation, but the mechanism by which this occurs is undefined. Regulation of the composition of the commensal bacterial community in the gut (i.e. the microbiota) could be one mechanism. IgA can be produced through T-cell-dependent (TD) and T-cell-independent (TiD) pathways. While TiD IgA is the most abundant IgA secreted into the gut, the relative contribution of TD and TiD IgA in regulating microbiota composition is controversial. Antigen presentation by B cells to T cells is essential for TD responses, and this is carried out by MHC class II …

Limitations And Consequences Of Migrant And Refugee Healthcare- An Analysis Of The Current State Of Migrant Health, Meghan Herilla

Senior Theses

Migrants and refugees are an often-neglected specialized population in the field of healthcare, although making up over 14% of the world’s population.

The following paper examines the current state of migrant healthcare, including but not limited to ease of access, quality of care, and the accompanying stigmatization of immigrants in general. It then analyzes current policies, both national and global, influencing the healthcare of immigrants in both the United States and abroad. Finally, a comparison of migrant healthcare in the United States versus Thailand shows how the current U.S. healthcare system can be improved to better accommodate migrants and refugees. …

The Demographics Of Death: An Early Look At Covid-19, Cultural And Racial Bias In America, Eddie Bernice Johnson, Lawrence J. Trautman

UC Law Constitutional Quarterly

During late 2019, reports emerged that a mysterious coronavirus was resulting in high contagion and many deaths in Wuhan, China. In just a few weeks, cases rose quickly in Seattle, spread to California, and the first in- stance of the virus appeared in New York (from Iran) on March 1, 2020. As the months pass, it is abundantly clear that less wealthy Americans have far fewer options amid the new normal of shelter-in-place orders, school closings, and shuttered businesses. For example, the poor and other populations may be genetically pre-disposed to heart disease and diabetic issues, but poverty also dictates …

Does Gender Climate Influence Climate Change? The Multidimensionality Of Gender Equality And Its Countervailing Effects On The Carbon Intensity Of Well-Being, Christina Ergas, Patrick Trent Greiner, Julius Alexander Mcgee, Matthew Thomas Clement

Urban Studies and Planning Faculty Publications and Presentations

The carbon intensity of well-being (CIWB) (a ratio measuring the amount of CO₂ emitted per unit of life expectancy at birth) is an increasingly popular way to measure the ecological efficiency of nations. Although research demonstrates that economic development typically reduces this efficiency, little research has explored the extent to which social equality improves it. This study uses panel data for 70 nations between 1995 and 2013 to assess how various aspects of gender equality affect the ecological efficiency of nations. We estimate a series of Prais-Winsten regression models with panel-corrected standard errors (PCSE) to assess how increases in …

A Program Development And Evaluation Project For Provider Use Of Buprenorphine Maintenance, Kyle Olson, Aprn

Doctor of Nursing Practice Projects

Background: Buprenorphine (BNX) is used in Opioid Use Disorder (OUD) deterrence. Optimal long-term duration with BNX is unclear, but evidence shows that there is a high risk for relapse when medicine is discontinued even if maintenance has been stable for some time.

Outcomes: The purpose of this project was to decrease barriers for providers implementing BNX therapy for individuals diagnosed with OUD. Outcomes measured included: (1) knowledge of and barriers to implementing current guidelines, (2) factors preventing use of guidelines, (3) recommendations for BNX maintenance as per guidelines.

Methods: Using a pre-post intervention design, participant knowledge on BNX guidelines, factors …

Prep Education Intervention, Kristina Jung Msn, Fnp-Bc

Doctor of Nursing Practice Projects

Background: The nation’s HIV infection rate is alarming, yet only a small percentage of eligible individuals are prescribed pre-exposure prophylaxis (PrEP). This sluggish PrEP uptake may be related to lack of knowledge among non-HIV specialist providers. Thus, interventions toexpand providers’ use of PrEP as an HIV prevention strategy are needed.

Objectives: The project aim was to develop an intervention to improve retail nurse practitioners’ (NP) knowledge for PrEP clinical practice, comfort screening for “at-risk HIV” patients, confidence prescribing PrEP, and likeliness to prescribe PrEP in the next six months.

Methodology: An online PrEP tutorial was implemented for retail clinic NPs. …

Use Of Imaging Flow Cytometry To Assess The Hematology Of Eastern Massasauga Rattlesnakes (Sistrurus Catenatus), Jennifer H. Kovach

Masters Theses

The federally threatened eastern massasauga rattlesnake is faced with many threats, including the newly recognized snake fungal disease. Unfortunately, the immune response to the disease is unknown. Leukocyte profiles are used as health assessment tools for many species, and imaging flow cytometry can be used as an application to characterize leukocyte profiles. Our goal was to use imaging flow cytometry to identify leukocyte profiles of eastern massasauga rattlesnakes and determine differences in profiles between sexes, reproductive status, ages, location, and individuals with clinical signs of snake fungal disease. Blood samples from 201 individuals were collected from ten locations throughout the …