Digital Commons Network^™

Optimization Of Perioperative Prophylaxis In Penicillin-Allergic Labeled Patients, Katie A. Vandervelde

Research Days

Problem Statement/Question: A penicillin (PCN)-allergy label is life-long and has been shown to result in more costly, less effective, and broader-spectrum antibiotics being utilized for surgical prophylaxis. At CMH, 6.6% of surgical patients receiving perioperative antibiotics are labeled PCN-allergic. A common myth is that approximately 10% of patients with a PCN-allergy history will experience an allergic reaction if administered a cephalosporin, whereas recent observational studies have found crossreactivity rates between 0.17-0.7%. Most of these patients receive a cefazolin alternative unnecessarily. Currently, no process exists to identify and clarify PCN-allergic patients preoperatively. Data from November 2018-December 2019 found ~2.33 patients per …

C-Reactive Protein Values To Predict Sepsis-Induced Inflammatory Response In Premature Infants, Megan H. Tucker

Research Days

Background: C-reactive protein (CRP) is an inflammatory marker that has been recognized as a biomarker of the systemic inflammatory response in preterm neonates. We hypothesized that initial and peak CRP values would correlate with the degree of sepsis-induced acute lung injury (ALI) as measured by the pulmonary severity score (PSS).

Objectives/Goal: 1) Determine if confirmed (CF) sepsis events are associated with higher initial and peak CRP values than rule out (RO) sepsis events. 2) Investigate if initial and/or peak CRP correlates with severity of sepsis-induced ALI as measured by the PSS.

Methods/Design: In this retrospective case control study, we included …

Diagnosis And Management Of Otitis Media With Effusion In Pediatric Urgent Care Clinics, Ashley Deschepper

Research Days

Background: Otitis media with effusion (OME)’s clinical presentation is often confused with acute otitis media (AOM) by providers. Despite OME guidelines recommending watchful waiting with no antibiotics, rates of antibiotic use remain elevated. In our pediatric urgent care clinics (UCCs), an estimated 50% of patients diagnosed with OME receive antibiotic prescriptions.

Objectives/Goal: To determine the provider diagnosis validity and the rates of antibiotics prescribed among pediatric OME patients evaluated in 3 UCCs within a pediatric healthcare system.

Methods/Design: We randomly selected 75% of encounters for children age 0-18 years who had a billing diagnosis of OME in 2019. Charts were …

2021-05-11_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

Covid-19 Newsletter (Vol. 71), Center For Disaster Medicine, New York Medical College

COVID-19 Newsletter

No abstract provided.

Covid-19: A Syndemic Requiring An Integrated Approach For Marginalized Populations, Rosemary M. Caron, Amanda Rodrigues Amorim Adegboye

Faculty Publications

The novel coronavirus, SARS-CoV-2, responsible for the COVID-19 pandemic, has challenged healthcare systems globally. The health inequities experienced by immigrants, refugees, and racial/ethnic minorities have been aggravated during the COVID-19 pandemic. The socioeconomic, political, and demographic profile of these vulnerable populations places them at increased risk of contracting COVID-19 and experiencing significant morbidity and mortality. Thus, the burden of the COVID-19 pandemic is disproportionally higher among these at-risk groups. The purpose of this perspective is to: (1) highlight the interactions among the social determinants of health (SDoH) and their bi-directional relationship with the COVID-19 pandemic which results in the current …

Increased Diagnosis Of Hepatocellular Carcinoma In Hospitalized Patients With Alcohol Related Hepatitis After The Covid-19 Outbreak: A Global Multi-Center Propensity Matched Analysis., Abhilash Perisetti Md, Randeep Kaur, Ragesh Thandassery

PCI Publications and Projects

No abstract provided.

Predicting Covid-19 Behavior: Is It All Due To Political Orientation?, Caleb Potts

Electronic Theses and Dissertations

ABSTRACT

Adherence to COVID-19 preventing measures is becoming increasingly important as governments across the world realize COVID-19 is not an acute, but a chronic problem. There is, however, disagreement over to what extent COVID-19 is a problem. In the United States, the division appears to be primarily along party lines (Democrat and Republican[1]), though even within parties there is division. This division might be explained by differences in: the behavioral immune system and trust in government. Additional factors to examine include: personality, fear of COVID-19, and religious beliefs. The present study used previously validated self-report measures to assess …

The Immune Microenvironment And Relation To Outcome In Patients With Advanced Breast Cancer Treated With Docetaxel With Or Without Gemcitabine, Elisabeth S. Stovgaard, Karama Asleh, Nazia Riaz, Samuel Leung, Dongxia Gao, Lise B. Nielsen, Anne-Vibeke Lænkholm, Eva Balslev, Maj-Britt Jensen, Dorte Nielsen, Torsten O. Nielsen

Centre for Regenerative Medicine & Stem Cell Research

Preclinical studies suggest that some effects of conventional chemotherapy, and in particular, gemcitabine, are mediated through enhanced antitumor immune responses. The objective of this study was to use material from a randomized clinical trial to evaluate whether patients with preexisting immune infiltrates responded better to treatment with gemcitabine + docetaxel (GD) compared to docetaxel alone. Formalin fixed, paraffin-embedded breast cancer tissues from SBG0102 phase 3 trial patients randomly assigned to treatment with GD or docetaxel were used. Immunohistochemical staining for CD8, FOXP3, LAG3, PD-1, PD-L1 and CD163 was performed. Tumor infiltrating lymphocytes (TILs) and tumor associated macrophages were evaluated. Prespecified …

Improving The Approach To Fellowship Trainee Feedback, Katie A. Vandervelde

Research Days

Problem Statement/Question: Giving and receiving feedback are difficult but necessary skills in medical training. We identified a need for improved feedback based on decreased learner satisfaction on our annual ACGME survey. In an anonymous survey, 2018-19 infectious disease fellows reported receiving formal feedback from 52.4% of their inpatient clinical experiences with faculty.

Background/Project Intent (Aim Statement): Increase the occurrence of feedback to fellows by faculty during clinical service rotations from 52.4% to >90.0% in 6 months utilizing a standardized method.

Methods (include PDSA cycles): A Feedback Card (Figure 1), was developed by fellows and faculty. Both parties were instructed to …

Pulmonary Severity Score As A Measure Of Sepsis-Induced Acute Lung Injury In Preterm Infants, Megan H. Tucker

Research Days

Background: Sepsis is the most common indirect cause of acute lung injury (ALI) in adult and pediatric patients, yet no studies have described this phenomenon in preterm infants. We hypothesize that sepsis-induced ALI occurs in neonates and increases the risk of bronchopulmonary dysplasia (BPD) in preterm infants.

Objectives/Goal: 1) To investigate whether late onset sepsis (LOS) and other systemic inflammatory diseases are temporally correlated with ALI as quantified by pulmonary severity score (PSS) trajectory. 2) To determine the sepsis subtypes associated with the greatest severity of ALI.

Methods/Design: We included infants < 31 weeks gestational age and < 1500 grams with LOS in this retrospective case control study. The PSS was calculated at 72, 48, and 24 hours (hr) prior to, at the time of, and 24, 48, 72, and 168hr after sepsis diagnosis. We further defined rule out (RO) sepsis (blood culture negative; antibiotics continued only 48-72hr), blood culture positive (Cx+) sepsis, necrotizing enterocolitis (NEC), urinary tract infection (UTI), and culture negative (Cx-) clinical sepsis (blood culture negative; antibiotics continued > 6 days; specific lab criteria met). PSS trajectories for …

Improving The Rate Of Ppsv-23 Vaccination In Children With Type I Diabetes, Henry S. Jeng Dr

Research Days

Background/Project Intent (Aim Statement): The routine use of PCV-13 has resulted in a dramatic reduction in the incidence of pneumococcal infections among young children. However, serious pneumococcal infections caused by additional vaccine serotypes continue to occur in older children with high-risk conditions.1 As per the CDC, children with Diabetes should receive the PPSV-23 vaccine beginning at 2 years of age and at least 8 weeks after their last indicated dose of PCV-13.2 A review of division data from March 2016 to November 2018 revealed that only 2.6% of the eligible patient population with Diabetes have received the PPSV-23 vaccine. More …

Ada News - 05/10/2021, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Columbia Chronicle (05/10/2021), Columbia College Chicago

Columbia Chronicle

Student newspaper from May 10, 2021 entitled The Columbia Chronicle. This issue is 14 pages. Cover story: "Columbia awaits a new beginning". Editors-in-Chief: Mari Devereaux & Brooklyn Kiosow.

2021-05-10_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

Covid Smell Tracker: A Research-Based Mobile Application To Study Smell Loss In Subjects With Covid-19, John Pueringer, Matthew Brennan, Tory Mcknight, Mindy Rabinowitz, Elina Toskala, Gurston Nyquist, Marc Rosen, Aykut Unsal

Research Day

Introduction: Up to 60% of people infected with SARS-CoV-2 report anosmia or ageusia during their disease course. “COVID Smell Tracker” is a smart phone application (app) developed to elucidate the onset, duration and extent of anosmia and ageusia through questionnaires.

Methods: “COVID Smell Tracker” is publicly available on smart phone devices (www.covidsmelltracker.org). Users complete surveys around demographics, medical history, COVID status and symptomology. Deidentified responses were collated and analyzed using descriptive statistics.

Results: Of the 266 users included, the majority were located in Europe (43%) and North America (33%). Male, Caucasian users were most common (54.9% and 61.7% respectively), followed …

Rapid Return To Normal Activities At A Residential Summer Camp During Covid-19 Pandemic, Anna Klunk, Rachel Holloway, Arash Babaoff, Eric Jelin

Research Day

Aim: Infection prevention and control (IPC) within residential settings is a central focus of the coronavirus disease 2019 (COVID-19) pandemic. Youth residential summer camps are an excellent model for such environments and have thus far had mixed results. The aim of this report is to describe the successful implementation of a seven-week overnight summer camp with rapid return to normal activities from June to August 2020

Subjects and Methods: This retrospective study includes 427 individuals who traveled from 24 US States. All staff and campers were tested by serial nasopharyngeal PCR tests in the context of strict infection prevention and …

Week Of May 10, 2021, New York Medical College

InTouch

• La Casita de la Salud Expands Services to Offer Medical and Dental Care in Westchester
• NYMC's Days of Giving Raises Nearly $345,000 to Support Student Scholarships
• NYMC Receives Grant from Alpha Omega Alpha to Support Educational Leadership Program to Combat Systemic Racism and Implicit Bias
• The Office of Diversity and Inclusion Hosts Leveraging Diversity in Academic Medicine Seminar
• School of Medicine Hosts Gold Humanism Honor Society Induction Ceremony for the Class of 2022
• Alpha Omega Alpha Iota Chapter Celebrates Academic Distinction During Annual Induction Ceremony
• NYMC Faculty Member, Abhay Dhand, M.D., Presents Keynote Address at Touro Research Day: COVID-19 One …

Short Term Safety, Immunogenicity, And Reproductive Effects Of Combined Vaccination With Anti-Gnrh (Gonacon) And Rabies Vaccines In Female Feral Cats, Shiri Novak, Boris Yakobson, Shir Sorek, Liat Morgan, Smadar Tal, Ran Nivy, Roni King, Lauren Jaebker, Douglas C. Eckery, Tal Raz

United States Department of Agriculture Wildlife Services: Staff Publications

Overpopulation of free-roaming cats is a major problem leading to negative impacts on animal health and welfare, public nuisance, transmission of zoonotic diseases, and well-documented harm to wildlife. Surgical sterilization had failed to provide a practical solution to free-roaming cats' overpopulation under field conditions; therefore, efficient and safe non-surgical immunocontraception methods are aspired. Rabies is a deadly virus that may infect people and animals. However, the safety and efficacy of combined vaccination with anti-GnRH and rabies vaccines in feral cats, which often suffer from disrupted health conditions and experienced high stress level, has never been studied. Therefore, our objective was …

Effects Of Message Frame And Cultural Orientations On Covid-19 Prevention Behaviors, Mika Hashimoto

Communication ETDs

This study aimed to explore effective message strategies to promote COVID-19 prevention behaviors among college students. Due to the fewer symptoms and lessened impact of COVID-19 in this population, young adults tend to have low perceived risk that results in low engagement in preventive behaviors. Also, some people may hold beliefs or values that are contrary to preventive behaviors. Thus, applying message framing theory, this study tested the effects of perceived risk and cultural orientation on adherence to prevention behaviors. The results showed that perceived risk and cultural orientation were associated with intention to maintain physical distance and wearing a …

Mapping Of The Global Productivity On Covid-19 Since The Origin Of The Pandemic, Dr.R. Santhakumar, Dr.K. Kaliyaperumal, Dr.P. Balasubramanian

Library Philosophy and Practice (e-journal)

The novel corona virus disease (COVID-19) is one of the most infectious diseases that primarily affect the lungs, which inflicted huge losses to the human beings of the globe. As its spread savagely, the literature of is also proliferated within a few months. It is the prime duty of this study to map the different aspects of this scientific literature by applying scientometrics techniques. The data related to this study are recorded in the Web of Science core collection, since the origin of the dreadful virus to January 2, 2021. Thus, 55049 articles have been published on COVID-19 in 22518 …

Short Term Safety, Immunogenicity, And Reproductive Effects Of Combined Vaccination With Anti-Gnrh (Gonacon) And Rabies Vaccines In Female Feral Cats, Shiri Novak, Boris Yakobson, Shir Sorek, Liat Morgan, Smadar Tal, Ran Nivy, Roni King, Lauren Jaebker, Douglas C. Eckery, Tal Raz

United States Department of Agriculture Wildlife Services: Staff Publications

Overpopulation of free-roaming cats is a major problem leading to negative impacts on animal health and welfare, public nuisance, transmission of zoonotic diseases, and well-documented harm to wildlife. Surgical sterilization had failed to provide a practical solution to free-roaming cats’ overpopulation under field conditions; therefore, efficient and safe non-surgical immunocontraception methods are aspired. Rabies is a deadly virus that may infect people and animals. However, the safety and efficacy of combined vaccination with anti-GnRH and rabies vaccines in feral cats, which often suffer from disrupted health conditions and experienced high stress level, has never been studied. Therefore, our objective was …

2021-05-09_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

Alzheimer’S And Patient Caregiver Burnout: A Comprehensive Review Of The Literature, Madeline J. Hekeler

Senior Honors Projects, 2020-current

The term ‘silent epidemic’ has become fitting for Alzheimer’s disease, as it is now the sixth leading cause of death in the US. Caring for AD patients at home in the US costs billions of dollars each year. The current comprehensive literature review discusses the background/history of AD, pathology and modes of transmission of AD, behavioral and natural risk factors, prevention and treatment options, and how the aforementioned factors contribute to caregiver burnout and subsequently affect the AD patient. The extensive examination of the literature determined several gaps to be addressed. More specifically, burnout among AD caregivers has become an …

An Automated Early Detection And Classification Method For Covid-19 Stages Based On Deep Learning Technique Using Chest Ct Images., Mohamed Abdelsalam, Mervat El-Seddek

Mansoura Engineering Journal

Coronavirus Disease 2019 (COVID-19) has widely spread all over the world since the ending of 2019. Until now, the death toll and injuries counted by the world's newest has not stopped. It is better to find an automatic classification technique to find out the extent of pneumonia, and be helpful tools for faster decisions in clinical practice. The Early detection of COVID-19 is an important and urgent need for stopping the spread of the disease. The aim of this study is to develop an automated early detection and classification method for COVID-19 patients based on deep learning technique using chest …

South Dakota State University One Hundred Thirty-Fifth Commencement Ceremonies, May 8-9, 2021, Brookings, South Dakota, South Dakota State University

Commencement Programs

Please note: The names listed in the program are not official confirmation of meeting the graduation requirements. Commencement for the 135th Commencement at South Dakota State University consists of morning and afternoon ceremonies on May 8th and May 9th. Each program will commence with introductions by University President Barry H. Dunn. Dennis D. Hedge, Provost and Vice President for Academic Affairs will acknowledge student honors and Lt. Col. Jason A. Haufschild, Air Force ROTC, and Lt. Col. Jason W. Kettwig, Army ROTC, recognizing Army and Air Force commissions for each ceremony. The SATURDAY MORNING ceremony (page 7) will mark the …

2021-05-08_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

Detection Of Neonicotinoids In Northern Leopard Frog (Rana Pipiens) Brains, Peyton G. Keller

Honors Thesis

Neonicotinoids are widespread and commonly used to fight agricultural pests. Unfortunately, these neurotoxic insecticides commonly reach nearby wetlands due to tile drainage systems and agricultural runoff. Non-target organisms, such as amphibians, use wetlands as habitat and are likely exposed to elevated neonicotinoid levels. We collected Northern leopard frogs and water samples from control and tile wetlands to compare imidacloprid brain concentrations and subsequent changes in brain morphology. Additionally, a lab-based experiment was conducted to further analyze the ability of imidacloprid and its metabolite, imidacloprid-olefin, to cross the blood-brain barrier. Tile wetlands had higher aquatic imidacloprid concentrations. Subsequently, amphibians collected from …

Intensification Of Coronavirus Scientific Literature During The First Four Months Of 2021, Rekha A. J, Doctor M. Jayaprakash Assistant Professor

Library Philosophy and Practice (e-journal)

For this research, the Web of Science database is being considered. This survey uncovered the contributions of various countries, research authors, and research areas, as well as the publication trend, country-specific research production, and top-cited papers in coronavirus literature.

The data set included papers on coronavirus that were downloaded between January 1, 2021, and April 30, 2021 from the Web of Science Core Collection (WOS CC). During the first four months of 2021, a total of 9905 documents were released. According to the report, the pandemic was covered by 158 nations, 60708 authors, and 13232 institutes. Overall, the United States, …

Multimodal Neuroimaging Of Hiv And Aging, Brandon Lew

Theses & Dissertations

HIV infection remains a significant contributor to disease burden, and with the success of antiretroviral therapies, the population of people with HIV is aging. A growing literature suggests a relationship between HIV-infection and a profile of age advancement, most notably in molecular studies of epigenetics. However, despite the widely-known high prevalence of HIV-related brain atrophy, functional deficits, and HIV-associated neurocognitive disorder (HAND), epigenetic age advancement has not been linked to HIV-related changes in neuroimaging metrics.

We applied three neuroimaging methods, structural MRI, resting state functional MRI, and resting state MEG, to study the brain structure and function of 121 virally-suppressed …