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2021

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The Conspiracy Theory Defense In Response To Whistleblower Accusations: Turning A Hero Into A Villain, James K. Beggan Jun 2021

The Conspiracy Theory Defense In Response To Whistleblower Accusations: Turning A Hero Into A Villain, James K. Beggan

Heroism Science

Whistleblowers can be viewed as heroic actors who reveal institutional misdeeds. In contrast, conspiracy theorists are seen as members of a marginalized element perpetuating misinformation. Despite this apparent difference, the present analysis focuses on how similarities between the two constructs can allow a target to discredit a whistleblower accusation by countering that the whistleblower is operating as part of a conspiracy. More generally, this paper considers how the difficulty inherent in disproving conspiracy theory claims facilitates their utility as a defense. The case study of President Donald Trump’s responses to whistleblower accusations are considered to illustrate the arguments.


Balanced Impacts Of Fitness And Drug Pressure On The Evolution Of Pfmdr1 Polymorphisms In Plasmodium Falciparum., Marvin Duvalsaint, Melissa D. Conrad, Stephen Tukwasibwe, Patrick K. Tumwebaze, Jennifer Legac, Roland A. Cooper, Philip J. Rosenthal Jun 2021

Balanced Impacts Of Fitness And Drug Pressure On The Evolution Of Pfmdr1 Polymorphisms In Plasmodium Falciparum., Marvin Duvalsaint, Melissa D. Conrad, Stephen Tukwasibwe, Patrick K. Tumwebaze, Jennifer Legac, Roland A. Cooper, Philip J. Rosenthal

Natural Sciences and Mathematics | Faculty Scholarship

BACKGROUND: Anti-malarial drug resistance may be limited by decreased fitness in resistant parasites. Important contributors to resistance are mutations in the Plasmodium falciparum putative drug transporter PfMDR1.

METHODS: Impacts on in vitro fitness of two common PfMDR1 polymorphisms, N86Y, which is associated with sensitivity to multiple drugs, and Y184F, which has no clear impact on drug sensitivity, were evaluated to study associations between resistance mediators and parasite fitness, measured as relative growth in competitive culture experiments. NF10 P. falciparum lines engineered to represent all PfMDR1 N86Y and Y184F haplotypes were co-cultured for 40 days, and the genetic make-up of the …


Current Clinical Approach Of Nosocomial Clostridium Difficileinfection, Frans Liwang, Robert Sinto Jun 2021

Current Clinical Approach Of Nosocomial Clostridium Difficileinfection, Frans Liwang, Robert Sinto

Jurnal Penyakit Dalam Indonesia

Hospital-acquired Clostridium difficile infection (CDI) has become one of the global threats because the incidence has increased in recent decades. This nosocomial infection is closely related to antibiotic use in health services and is commonly found in the elderly. Antibiotics can promote colonization and CDI by intestinal microbiota dysbiosis and complex innate immune system activation. The manifestation also has a wide spectrum, ranging from mild diarrhea to fulminant colonic mucosal necrosis. Given that not all colonized subjects will be infected, further investigations such as toxigenic culture, nucleic-acid detection, and stool immunologic tests are only useful in symptomatic cases. In all …


Artistic Leadership In Minnesota Community Theater, Darlene Olson Jun 2021

Artistic Leadership In Minnesota Community Theater, Darlene Olson

Doctorate in Education

Minnesota artistic directors working in community theater benefit the communities they serve. The purpose of this narrative research and case study was to understand how the artistic director furthers equity and diversity in their leadership roles. Artistic directors see their practice as transforming and supporting diversity. The artistic directors' voice and viewpoints were from their own contextual situation and experiences in the field of education, leadership, and theater arts practice. The primary unit of this interpretative study was the community theater sites, its context, and the artistic directors' leadership experience. The semi-structured interviews were scheduled via Zoom during the 2020-2021 …


Isolation And Identification Of Candida Species And Some Superficial Mycosis Associated With Diaper Dermatitis In Erbil City, Vian B. Nehmatulla Jun 2021

Isolation And Identification Of Candida Species And Some Superficial Mycosis Associated With Diaper Dermatitis In Erbil City, Vian B. Nehmatulla

Polytechnic Journal

Diaper dermatitis (DD) is the most common cutaneous diagnosis in infancy that affects almost every child during the early months of their life time; most cases are associated with the yeast colonization of Candida or DD candidiasis and some dermatophytes. It is an irritating and inflammatory acute dermatitis in the perineal and perianal areas resulting from the occlusion and irritation caused by diapers. The study aimed to assess the association between Candida species and some dermatophytes in infants with napkin dermatitis and determine the prevalence of DD in relation with yeast (Candida) colonization and identify common Candida spp. which is …


Closing Gaps In The Care Of Patients With Heart-Kidney Disease: The Time Is Now., Janani Rangaswami Jun 2021

Closing Gaps In The Care Of Patients With Heart-Kidney Disease: The Time Is Now., Janani Rangaswami

Department of Medicine Faculty Papers

No abstract present.


Prevalence Of Cutibacterium Acnes And Staph Spp. In The Lesions Of Acne Vulgaris In Jakarta, Melyawati Hermawan, Enty Tjoa, Inneke J. Hidajat, Maria Teressa, Eka B. Layadi, Alegra Wolter Jun 2021

Prevalence Of Cutibacterium Acnes And Staph Spp. In The Lesions Of Acne Vulgaris In Jakarta, Melyawati Hermawan, Enty Tjoa, Inneke J. Hidajat, Maria Teressa, Eka B. Layadi, Alegra Wolter

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Acne vulgaris (AV) is a chronic skin disorder that is commonly seen in young adults. Recent studies have shown that bacteria other than Cuticubacterium acnes found in the skin microbiota also play vital roles in the pathogenesis of AV. Understanding the skin microbiota and its disruption in patients with AV is paramount in treating patients with AV.

Methods: Samples were obtained from 36 subjects to evaluate the proportion of Cutibacterium acnes, Staphylococcus epidermidis, and Staphylococcus aureus in lesions of AV by means of bacterial culture.

Results: There were 69 specimens collected from the 36 subjects with …


Metal Oxide Sensor Array Test Bed Prototype For Diagnostic Breath Analysis, Tiffany C. Miller Jun 2021

Metal Oxide Sensor Array Test Bed Prototype For Diagnostic Breath Analysis, Tiffany C. Miller

USF Tampa Graduate Theses and Dissertations

Detection of specific target biomarkers is a critical step for electronic nose technologies in breath analysis. Electronic nose technologies have been successfully demonstrated in the air quality, meat processing, and the citrus industries, as well as cancer clinical trials. The novel design, assembly, and implementation of a test bed prototype of an electronic nose system is introduced in this Dissertation. To verify the feasibility of a test bed prototype design, a Corona Virus Disease 2019 (COVID-19) breath simulation mixture of alcohol, acetone, and carbon monoxide was presented to the test bed prototype in the laboratory. The COVID-19 breath simulation mixture …


Human Health Threat And Economic Vulnerability: A Case Study On The Covid-19 Pandemic, Mirah Satria Alamsyah, Muhammad Faizal Alfian, Miftah Farid Darussalam Jun 2021

Human Health Threat And Economic Vulnerability: A Case Study On The Covid-19 Pandemic, Mirah Satria Alamsyah, Muhammad Faizal Alfian, Miftah Farid Darussalam

Global: Jurnal Politik Internasional

This paper frames the approach to determining policies in response to the COVID-19 pandemic, which either prioritise human health security protection or economic vulnerability. In this paper, the human security concept will be used to explain COVID-19 as a health security problem due to the existence of an existential threat. However, the same approach is not applicable in looking at COVID-19 as an economic security problem. Because the existential threat is less visible in human economic security aspects, it tends to be more appropriate to look at COVID-19 as the stressor that strengthens human vulnerabilities. This paper uses a qualitative …


A Rare Fatal Case Of Adenovirus Serotype 4 Associated Acute Disseminated Encephalomyelitis In An Adult: A Case Report, Zahra Qamar, Catherine Tucker, Lawrence C. Kenyon, Tricia. Royer Jun 2021

A Rare Fatal Case Of Adenovirus Serotype 4 Associated Acute Disseminated Encephalomyelitis In An Adult: A Case Report, Zahra Qamar, Catherine Tucker, Lawrence C. Kenyon, Tricia. Royer

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Acute disseminated encephalomyelitis (ADEM) is an autoimmune demyelinating disease directed against the myelin sheath of the central nervous system that typically presents 1–4 weeks after an infection or vaccination, most commonly in children. We describe a case of a young female who presented with rapidly progressive mental deterioration and died secondary to ADEM following an adenovirus upper respiratory tract infection.


Mandatory Social Distancing For Covid-19 Outbreak And Its Economic Consequences In West Sumatera - Indonesia, Endrizal Ridwan, Besti Novianda Jun 2021

Mandatory Social Distancing For Covid-19 Outbreak And Its Economic Consequences In West Sumatera - Indonesia, Endrizal Ridwan, Besti Novianda

Jurnal Ekonomi Kesehatan Indonesia

The Governor of West Sumatra Province of Indonesia imposed a mandatory social distancing (PSBB) to slow down the Covid-19 outbreak from 22 April to 7 June 2020. The cons argued that PSBB was ineffective because of the impossibility to limit people’s movements. The pros, on the other hand, viewed PSBB as a training facility to increase people’s awareness about the pandemic. Our research aims at evaluating the effectiveness of PSBB by using the Kermack-McKendrick SIR pandemic model and the NLSUR non-linear least square estimation. Using daily data published by the Covid-19 task force, we found that PSBB had a positive …


Berat Badan Lahir Rendah (Bblr) Sebagai Determinan Terjadinya Ispa Pada Balita Analisis Data Sdki Tahun 2017, Desinta Ayu Lestari, Asri Adisasmita Prof Jun 2021

Berat Badan Lahir Rendah (Bblr) Sebagai Determinan Terjadinya Ispa Pada Balita Analisis Data Sdki Tahun 2017, Desinta Ayu Lestari, Asri Adisasmita Prof

Jurnal Epidemiologi Kesehatan Indonesia

No abstract provided.


Palm Oil Price–Exchange Rate Nexus In Indonesia And Malaysia, Afees A. Salisu, Abdulsalam Abidemi Sikiru Jun 2021

Palm Oil Price–Exchange Rate Nexus In Indonesia And Malaysia, Afees A. Salisu, Abdulsalam Abidemi Sikiru

Bulletin of Monetary Economics and Banking

In this study, we extend the literature analyzing the predictive content of commodity prices for exchange rates by examining the role of palm oil price. Our analysis focuses on Indonesia and Malaysia, the two top producers and exporters of palm oil, and utilizes daily data covering the period from December 12, 2011 to March 29, 2021, which is partitioned into two sub-samples based on the COVID-19 pandemic. Relying on a methodology that accommodates some salient features of the variables of interest, we find that on average the in-sample predictability of palm oil price for exchange rate movements is stronger for …


Examining Inequities In Rates Of Undiagnosed Hiv And Rectal Stis In A Large Nationwide Cohort Study Of Sexual Minority Men, H Jonathon Rendina, Ali Talan, K Marie Sizemore, Nicola F. Tavella, Brian Salfas, Ore Shalhav, Drew Westmoreland, Brian Mustanski, Carlos E. Rodríguez- Díaz Jun 2021

Examining Inequities In Rates Of Undiagnosed Hiv And Rectal Stis In A Large Nationwide Cohort Study Of Sexual Minority Men, H Jonathon Rendina, Ali Talan, K Marie Sizemore, Nicola F. Tavella, Brian Salfas, Ore Shalhav, Drew Westmoreland, Brian Mustanski, Carlos E. Rodríguez- Díaz

Publications and Research

Objective Sexual minority men (SMM) of colour are disproportionately impacted by HIV and bacterial STIs (bSTIs). To better understand within-group heterogeneity and differential risk factors by race and ethnicity, we sought to examine rates of undiagnosed HIV and rectal bSTI at the intersection of racial and ethnic identity with other sociodemographic factors.

Methods We examined data from 8105 SMM conducting home-based self-testing at enrollment in a nationwide cohort study collected from November 2017 to August 2018. We conducted analyses stratified by racial and ethnic groups to examine within- group (ie, subgroup) unadjusted rates of HIV and rectal bSTI infection across …


Microfluidic Paper-Based Analytical Device (Μpad) For Determining Hydroquinone In Facial Whitening Cream Using Phloroglucinol Reagent, Hermin Sulistyarti, Paradhita Ayu Puspitaloka, Boyfannie Ivan Putra, Rurini Retnowati, Herman Tolle Jun 2021

Microfluidic Paper-Based Analytical Device (Μpad) For Determining Hydroquinone In Facial Whitening Cream Using Phloroglucinol Reagent, Hermin Sulistyarti, Paradhita Ayu Puspitaloka, Boyfannie Ivan Putra, Rurini Retnowati, Herman Tolle

Makara Journal of Science

A microfluidic paper-based analytical device (µPAD) is developed in this work to analyze hydroquinone in facial whitening creams using phloroglucinol. The µPAD features a hydrophobic barrier for detection and was fabricated using a wax printer with Whatman chromatographic paper. Detection was achieved by colorimetry based on the formation of an orange hydroquinone–phloroglucinol complex. The colored reaction product formed on the detection zone of the µPAD was scanned, and the images obtained were processed with Image-J software to determine their color intensity (RGB value). Optimization of the process conditions was conducted to achieve sensitive measurements. The optimum conditions yielding maximum sensitivity …


Diaspora By Design: The Systematic Displacement Of Tampa's African-American Populace, 1925-1974, Shannon D. Bruffett Jun 2021

Diaspora By Design: The Systematic Displacement Of Tampa's African-American Populace, 1925-1974, Shannon D. Bruffett

USF Tampa Graduate Theses and Dissertations

Diaspora by Design: The Systematic Displacement of Tampa’s African-American Populace, 1925-1974 is a political and economic history that maps the transformation of the city’s urban landscape through a variety of federal programs. It examines the the ways that Tampa city leaders employed a variety of federal programs, and funding, to shape the economic, social, and cultural environment of Tampa’s Black population over the course of five decades.


Bagaimana Media Memberitakan Pandemi: Analisis Isi Berita Mengenai Covid-19 Di Detik.Com Dan Kompas.Com, Ghina Aribah, Dien Anshari Jun 2021

Bagaimana Media Memberitakan Pandemi: Analisis Isi Berita Mengenai Covid-19 Di Detik.Com Dan Kompas.Com, Ghina Aribah, Dien Anshari

Perilaku dan Promosi Kesehatan: Indonesian Journal of Health Promotion and Behavior

Introduction. During the pandemic COVID-19, online news is one of the most accessible channels to disseminate information about the current situation and prevent and mitigate the disease. Objective to get the portrayals of risk communication in news articles about the COVID-19 pandemic Methods. Used content analysis method with descriptive quantitative approach. Data came from selecting news articles published by detik.com and kompas.com in March and April 2020 using a stratified proportional random sampling technique. Results. There were limited news articles that provide epidemiology information, disease characteristics, how to mitigate the disease, the non-health effects of COVID-19, and criticism of the …


Hubungan Antara Pengetahuan Dan Sikap Dengan Perilaku Pencegahan Covid-19 Pada Peserta Seminar Online Stikes Raflesia 7 April 2020, Susilawati Gunawan, Iis Sinsin, Andri Yan Prima Zani Jun 2021

Hubungan Antara Pengetahuan Dan Sikap Dengan Perilaku Pencegahan Covid-19 Pada Peserta Seminar Online Stikes Raflesia 7 April 2020, Susilawati Gunawan, Iis Sinsin, Andri Yan Prima Zani

Perilaku dan Promosi Kesehatan: Indonesian Journal of Health Promotion and Behavior

Introduction. Early in 2020, the world was shocked by the COVID-19 pandemic. The increasing number of cases was fast and spread to various countries. The rapid spread and the number of cases increasing have resulted in the importance of socialization and education on preventing and controlling this infectious disease. The community must play a role in breaking the chain of COVID-19 transmission by implementing health protocols. Objective. to find out the knowledge, attitudes and practices of the community to prevent the spread of the COVID-19 Methods. used a quantitative approach with a cross-sectional design by distributing questionnaires online using the …


Global Actors’ Effort Towards Gender Equality In Women's Health In East And Southern Africa, Alvela Salsabilah Putri, Puti Jasmine Choirunissa, Riana Salma Jun 2021

Global Actors’ Effort Towards Gender Equality In Women's Health In East And Southern Africa, Alvela Salsabilah Putri, Puti Jasmine Choirunissa, Riana Salma

Global: Jurnal Politik Internasional

According to 2020 UNAIDS data, there are approximately 20,700,000 people infected with HIV, with 12,900,000 infected are women in Eastern & Southern Africa. This condition is caused by the lack of health rights for women which is also based on the limited rights of women to matters such as education, employment and finance. This study aims to examine the role of global government in accommodating global actors to address issues of gender equality in women's health in Eastern and Southern Africa. This research is built on the concept of global governance theory and feminism. The research method used is qualitative …


Knowledge And Practices Of Mothers About Diarrhea In Children Under Three Years Old In Heevi Pediatric Teaching Hospital In Duhok City, Omed S. Saadallah, Gulistan A. Saido Jun 2021

Knowledge And Practices Of Mothers About Diarrhea In Children Under Three Years Old In Heevi Pediatric Teaching Hospital In Duhok City, Omed S. Saadallah, Gulistan A. Saido

Polytechnic Journal

Background and Objectives: Diarrheal disease is the second important reason of death in children under 5 years old and is responsible for killing around 760,000 children every year. Diarrhea can last for several days and it can leave the body without the water and salts that are necessary for survival. Most people who die from diarrhea actually die from severe dehydration and fluid loss. The aim of this study is to assess the relationship between mother’s knowledge and their practice about diarrhea in children mother’s knowledge and their practice about diarrhea in children less than 3 years old in Heevi …


Covid-19 Awareness System Based On Risk Assessment (Covid-19 Handling Implementation In Universitas Pekalongan), Yuniarti, Ristiawati, Nur Susanti Jun 2021

Covid-19 Awareness System Based On Risk Assessment (Covid-19 Handling Implementation In Universitas Pekalongan), Yuniarti, Ristiawati, Nur Susanti

Media Kesehatan Masyarakat Indonesia

World Health Organization (WHO) announced COVID-19 as a global pandemic since it occurred massively in the whole part of the world. COVID-19 has an impact on life’s aspects, including the academic life aspect. This study aims to assess the risk factors of COVID-19 to build an awareness system of COVID-19 in higher education. This research is qualitative research with a case study approach regarding the risks of COVID-19 at Universitas Pekalongan. Variables were including risk identification, risk analysis, and risk evaluation. Information about the data source, including a university leader, and its vice, acts as a primary informant, the leader …


Comparison Of Clinical Characteristics And Outcomes Between Covid-19 Pneumonia And H1n1 Influenza, Nosheen Nasir, Iffat Khanum, Kiren Habib, Rimsha Ahmed, Mujahid Hussain, Zahra Hasan, Muhammad Irfan Jun 2021

Comparison Of Clinical Characteristics And Outcomes Between Covid-19 Pneumonia And H1n1 Influenza, Nosheen Nasir, Iffat Khanum, Kiren Habib, Rimsha Ahmed, Mujahid Hussain, Zahra Hasan, Muhammad Irfan

Department of Medicine

Introduction: The COVID-19 pandemic has been likened to the 2009 H1N1 influenza pandemic. We aim to study the similarities and differences between patients hospitalized with COVID-19 and H1N1 influenza in order to provide better care to patients, particularly during the co-circulation of Influenza A Subtype H1N1 and SARS-CoV-2.
Material and methods: A retrospective cohort study was conducted in order to compare clinical characteristics, complications, and outcomes of hospitalized patients with PCR-confirmed H1N1 influenza pneumonia and COVID-19 at a tertiary care center in Karachi, Pakistan.
Results: A total of 115 patients hospitalized with COVID-19 were compared with 55 patients with H1N1 …


In Vitro Antibacterial Activity Of Mentha Spicataessential Oil Against Some Pathogenic Bacteria, Sara I. Othman, Fouad H. Kamel Jun 2021

In Vitro Antibacterial Activity Of Mentha Spicataessential Oil Against Some Pathogenic Bacteria, Sara I. Othman, Fouad H. Kamel

Polytechnic Journal

Mentha spicata (M. spicata) is within family Lamiaceae that spreads mainly in the temperate and subtemperate zones of the world. It is considered as a good source of essential oils (EOs), which is widely used in food production and pharmaceutical industries. The aim of the current study is to evaluate antibacterial activities associated with the EO of M. spicata cultivated in Iraq-Erbil city. The aerial parts of M. spicata were subjected to hydro distillation to extract the oil. Antimicrobial potential was tested against many microorganisms, signifying Gram-negative and Gram-positive bacteria. EO of M. spicata demonstrated antimicrobial activities with best susceptibility …


Comparative Study Of Perinatal Mortality, Stillbirths, And Neonatal Mortality From 2010 To 2018 In Developing And Developed Nations With Reference To Malaysia, Sujata Khobragade, Yadneshwar Khobragade, Adinegara Lutfi Abas Jun 2021

Comparative Study Of Perinatal Mortality, Stillbirths, And Neonatal Mortality From 2010 To 2018 In Developing And Developed Nations With Reference To Malaysia, Sujata Khobragade, Yadneshwar Khobragade, Adinegara Lutfi Abas

Manipal Journal of Medical Sciences

Background: Malaysia being an emerging economy has done well in the health sector. The perinatal mortality is reduced significantly but a slight upward trend was seen after 2015 in less developed states. This prompted us to conduct a review of perinatal, stillbirth, and neonatal deaths in Malaysia and compare them with other developing and developed countries. Aims and objectives: To find out: (1) Perinatal, neonatal and stillbirth rates from 2010 to 2018 in Malaysia, and (2) Compare it with developed and developing countries for the same duration. (3) To study contributary factors responsible for perinatal mortality, stillbirths and neonatal deaths …


Clinical Teaching And Learning In The Covid-19 Era And Beyond: The Emergent And Emerging Scenarios, Shashikala K. Bhat, Veena Manja, Vinutha Shankar, Shashikiran Umakanth Jun 2021

Clinical Teaching And Learning In The Covid-19 Era And Beyond: The Emergent And Emerging Scenarios, Shashikala K. Bhat, Veena Manja, Vinutha Shankar, Shashikiran Umakanth

Manipal Journal of Medical Sciences

The need for social distancing due to the COVID-19 pandemic has compromised traditional medical education. Educators and students in low-resource settings face diverse challenges in clinical teaching, learning, and assessment. The pandemic has necessitated a rapid transition from traditional pedagogical strategies to virtual platforms. Challenges in low resource settings include knowledge and training in technology, limited resource allocation for faculty development in virtual teaching methods, and financial constraints limiting the use of available technologies. There is also a lack of constructive alignment between outcomes, instructional strategies, and assessment of curriculum delivery in virtual platforms as the earlier curriculum design was …


Studi Endemisitas Dan Epidemiologi Deskriptif Malaria Di Kabupaten Purbalingga Tahun 2010-2019, Ghea Efranandhita Sukendar, Dwi Sarwani Sri Rejeki Jun 2021

Studi Endemisitas Dan Epidemiologi Deskriptif Malaria Di Kabupaten Purbalingga Tahun 2010-2019, Ghea Efranandhita Sukendar, Dwi Sarwani Sri Rejeki

Jurnal Epidemiologi Kesehatan Indonesia

Salah satu permasalahan kesehatan di Jawa Tengah adalah kejadian malaria. Kondisi lingkungan dan perilaku mempunyai peran dalam penyebaran malaria. Gambaran endemisitas dan upaya pengendalian yang diperlukan sebagai dasar perencanaan tindakan pengendalian malaria. Belum ada data yang menyajikan endemisitas malaria dari tahun 2010-2019 di Kabupaten Purbalingga. Penelitian ini bertujuan untuk mendeskripsikan endemisitas dan menggambarkan kejadian malaria berdasarkan variabel orang, tempat dan waktu dan upaya pengendalian yang sudah dilakukan periode tahun 2010-2019 di Kabupaten Purbalingga. Jenis penelitian yaitu deskriptif kuantitatif dengan populasi yaitu seluruh kasus malaria yang tercatat di dinas Kesehatan Kabupaten Purbalingga periode Januari 2010 sampai Desember 2019. Sampel merupakan total …


A Clinical Study To Optimise A Sand Fly Biting Protocol For Use In A Controlled Human Infection Model Of Cutaneous Leishmaniasis (The Flybite Study), Vivak Parkash, Helen Ashwin, Jovana Sadlova, Barbora Vojtkova, Georgina Jones, Nina Martin, Elizabeth Greensted, Victoria Allgar, Shaden Kamhawi, Jesus G. Valenzuela, Alison M. Layton, Charles L. Jaffe, Petr Volf, Paul M. Kaye, Charles J.N. Lacey Jun 2021

A Clinical Study To Optimise A Sand Fly Biting Protocol For Use In A Controlled Human Infection Model Of Cutaneous Leishmaniasis (The Flybite Study), Vivak Parkash, Helen Ashwin, Jovana Sadlova, Barbora Vojtkova, Georgina Jones, Nina Martin, Elizabeth Greensted, Victoria Allgar, Shaden Kamhawi, Jesus G. Valenzuela, Alison M. Layton, Charles L. Jaffe, Petr Volf, Paul M. Kaye, Charles J.N. Lacey

Peninsula Medical School

Background: Leishmaniasis is a globally important yet neglected parasitic disease transmitted by phlebotomine sand flies. With new candidate vaccines in or near the clinic, a controlled human challenge model (CHIM) using natural sand fly challenge would provide a method for early evaluation of prophylactic efficacy. Methods: We evaluated the biting frequency and adverse effects resulting from exposure of human volunteers to bites of either Phlebotomus papatasi or P. duboscqi, two natural vectors of Leishmania major. 12 healthy participants were recruited (mean age 40.2 ± 11.8 years) with no history of significant travel to regions where L. major-transmitting sand flies are …


June 29, 2021 Ereporter, University Of Alabama At Birmingham Jun 2021

June 29, 2021 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


Plethora Of Periodicals For The Public, Scott N. West Jun 2021

Plethora Of Periodicals For The Public, Scott N. West

University Libraries Blog Archive

Government-issued magazines cover the gamut of topics from military history and the humanities to health care and the teaching of English — and they're all free.


Covid-19 Newsletter (Vol. 78), Center For Disaster Medicine, New York Medical College Jun 2021

Covid-19 Newsletter (Vol. 78), Center For Disaster Medicine, New York Medical College

COVID-19 Newsletter

No abstract provided.