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2021

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Availability And Adequacy Of Water, Sanitation And Hygiene (Wash) Facilities In Secondary Schools, Rotimi Williams Olatunji, Noeem Thanny Taiwo Jul 2021

Availability And Adequacy Of Water, Sanitation And Hygiene (Wash) Facilities In Secondary Schools, Rotimi Williams Olatunji, Noeem Thanny Taiwo

Journal of Environmental Science and Sustainable Development

Hand-washing practice, which is globally recognized as the simplest, most affordable and effective way of curtailing the spread of infectious diseases, is still low in developing countries. This is largely influenced by the dearth and adequacy of Water, Sanitation and Hygiene (WASH) facilities. This paper investigated the level of availability and adequacy of WASH facilities in secondary schools in a developing, sub-Sharan country, particularly Lagos State, Nigeria. Protection Motivation Theory (PMT) guided this research. In all, 620 pupils were selected through multi-stage sampling methods. Two local government areas were selected from each of the three senatorial zones in the study …


Voluntary Behavior Modification During A Pandemic: Perceptions And Behaviors Toward Covid-19 In Japan, Firman Budianto, Yuichi Nishikori Jul 2021

Voluntary Behavior Modification During A Pandemic: Perceptions And Behaviors Toward Covid-19 In Japan, Firman Budianto, Yuichi Nishikori

Makara Human Behavior Studies in Asia

This study examines social measures meant to stop the spread of COVID-19 in Japan, where COVID-19 control relies heavily on the voluntary compliance of citizens. We examine how the government's campaign for controlling COVID-19 is perceived by people, and how these measures influenced people’s attitudes and behavior. This paper specifically discusses how people’s perceptions regarding COVID-19 control measures temper orthodox understandings of behavior modification, such as perceived threats, and how it influences their attitude and behavior. Qualitative data collected from an online open-ended questionnaire was cross-sectionally analyzed. This study argues that high risk perception is actually just one of many …


The Tumor Immune Environment Of Chronic Lymphocytic Leukemia, Patricia C. Montes, Priyanka Khare, Ronghua Zhang, Sheighlah D. Mcmanus, Maria Teresa S. Bertilaccio Jul 2021

The Tumor Immune Environment Of Chronic Lymphocytic Leukemia, Patricia C. Montes, Priyanka Khare, Ronghua Zhang, Sheighlah D. Mcmanus, Maria Teresa S. Bertilaccio

Summer Experience 2021

No abstract provided.


Plasmablastic Lymphoma Of The Kidney In A Previously Undiagnosed Hiv Patient, Amrita Valluri, Adarsh Sidda, Anisha Valluri, Gurusidda Manu, Niru Nahar Jul 2021

Plasmablastic Lymphoma Of The Kidney In A Previously Undiagnosed Hiv Patient, Amrita Valluri, Adarsh Sidda, Anisha Valluri, Gurusidda Manu, Niru Nahar

Marshall Journal of Medicine

We present the case of a 61-year-old male who presented with flank pain and dysuria. A biopsy and histopathological analysis of a mass found in the left kidney led to the diagnosis of plasmablastic lymphoma (PBL). The kidney is not a commonly reported site of presentation for PBL in the current literature.1,2 As a part of routine workup, HIV testing was ordered resulting in positive preliminary and confirmatory results. The patient denied awareness of his HIV status. Chemotherapy with uricosuric agents and antiretroviral therapy was initiated, but the patient developed tumor lysis syndrome with phosphate nephropathy leading to discontinuation …


Retelling Mecca: Shifting Narratives Of Sacred Spaces In Volga-Ural Muslim Hajj Accounts, 1699–1945, Danielle Ross Jul 2021

Retelling Mecca: Shifting Narratives Of Sacred Spaces In Volga-Ural Muslim Hajj Accounts, 1699–1945, Danielle Ross

History Faculty Publications

This article examines how Volga-Ural Muslims narrated their encounters with the sacred spaces visited during the hajj. It examines nine accounts hajj composed from the 1690s to the 1940s, to consider how changes in international politics, Russia’s domestic politics, and the culture of Islamic learning within the Volga-Ural Muslim community led to writers to revise narratives of why the sacred spaces of Mecca were sacred, how best to experience the power of these sacred spaces, and how these sacred spaces fit into the local culture of Volga-Ural Islam under Russian and Soviet rule.


School Of Medicine Celebrates New Endowed Chairs And Professors, Jane Longshore Jul 2021

School Of Medicine Celebrates New Endowed Chairs And Professors, Jane Longshore

Browse All News

No abstract provided.


The Impact Of Covid-19 On Church Gatherings In The Philippines: A Policy Analysis, Grace Zurielle Malolos, Joseph Christian Obnial, Rena Mallillin, Pamela Bianca Pasco, Erika Ong, Arianne Andes, Faith Ann Apat, Emma Teresa Carmela Aportadera, Rafael Valencia, Don Eliseo Lucero-Prisno Iii Jul 2021

The Impact Of Covid-19 On Church Gatherings In The Philippines: A Policy Analysis, Grace Zurielle Malolos, Joseph Christian Obnial, Rena Mallillin, Pamela Bianca Pasco, Erika Ong, Arianne Andes, Faith Ann Apat, Emma Teresa Carmela Aportadera, Rafael Valencia, Don Eliseo Lucero-Prisno Iii

Ateneo School of Medicine and Public Health Publications

The Philippines is the largest Christian-majority country in Asia. With church gatherings playing a vital role in the nature of Christianity in the Filipino culture, the advent of the coronavirus disease (COVID-19) pandemic in the Philippines posed challenges to public religious practices amid efforts to mitigate COVID-19 community transmission. Various policy pronouncements from both the government-led Inter-Agency Task Force (IATF) on Emerging Diseases and the church-led Catholic Bishops’ Conference of the Philippines (CBCP) were issued. These guidelines were implemented in order to address the two-pronged problem on healthcare and religious obligations. While these guidelines were initially contributory to the mitigation …


Field Safety Experience With An Autologous Cancer Vaccine In Tumor-Bearing Cats: A Retrospective Study Of 117 Cases (2015-2020), Michael D. Lucroy, Alexa M. Kugler, Ferris El-Tayyeb, Ryan M. Clauson, Ashley E. Kalinauskas, Mark A. Suckow Jul 2021

Field Safety Experience With An Autologous Cancer Vaccine In Tumor-Bearing Cats: A Retrospective Study Of 117 Cases (2015-2020), Michael D. Lucroy, Alexa M. Kugler, Ferris El-Tayyeb, Ryan M. Clauson, Ashley E. Kalinauskas, Mark A. Suckow

Office of the Attending Veterinarian Academic Publications

OBJECTIVES: The aim of this study was to determine the frequency and severity of adverse events (AEs) reported from use of an adjuvanted whole-cell autologous cancer vaccine in cats with solid tumors under field conditions.

METHODS: The case accession database at Torigen Pharmaceuticals was searched to identify client-owned cats that underwent biopsy or surgical resection of their primary tumor, had histologic confirmation of neoplasia and received at least one subcutaneous dose of an adjuvanted whole-cell autologous cancer vaccine. Records were reviewed for any reported AEs.

RESULTS: In total, 117 cats met the inclusion criteria and received 422 doses of autologous …


July 30, 2021 Ereporter, University Of Alabama At Birmingham Jul 2021

July 30, 2021 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


A Distinct Difference Between Air And Mucosal Temperatures In Human Respiratory Tract, Mehdi Khosravi, Ruei-Lung Lin, Ashish P. Maskey, Subodh Pandey, An-Hsuan Lin, Lu-Yuan Lee Jul 2021

A Distinct Difference Between Air And Mucosal Temperatures In Human Respiratory Tract, Mehdi Khosravi, Ruei-Lung Lin, Ashish P. Maskey, Subodh Pandey, An-Hsuan Lin, Lu-Yuan Lee

Internal Medicine Faculty Publications

xtensive evidence indicates that several types of temperature-sensitive ion channels are abundantly expressed in the sensory nerves innervating airway mucosa. Indeed, airway temperature is known to play an important role in regulating respiratory functions. However, the actual airway mucosal temperature and its dynamic changes during the respiratory cycle have not been directly measured. In previous studies, airway tissue temperature was often estimated by indirect measurement of the peak exhaled breath temperature (PEBT). In view of the poor thermal conductivity of air, we believe that the airway tissue temperature cannot be accurately determined by the exhaled air temperature, and this study …


Determinants In Investment Behaviour During The Covid-19 Pandemic, Angelin S. Kiruba, Vasantha Vasantha Jul 2021

Determinants In Investment Behaviour During The Covid-19 Pandemic, Angelin S. Kiruba, Vasantha Vasantha

The Indonesian Capital Market Review

This study investigated the psychological behaviour of investors in the stock market during the period of COVID-19. The survey was conducted between April and June 2020, following the lockdown announcement of the Indian Government on 25th March. There were 400 respondents. This paper has attempted to identify the impact on psychological behaviour during the initial stage of COVID-19 in India. The collected data has been used to determine the psychological factors which may have influenced investment decisions. The statistical tools of Cronbach Alpha, factor analysis, descriptive analysis, and multiple regression techniques were applied using the SPSS 21 package. The study …


A Multidimensional Welfare Status Of Leprosy Patients Living In A Suburban Area, Yunia Irawati, Sri Linuwih Sw Menaldi, Melinda Harini, Luh Karunia Wahyuni, Wanarani Alwin, Astari Dwiranti, Adhityawarman Menaldi, Sonny Tirta Luzanil, Qaishum Matsurah, Dadun ., Rico Kurniawan, Ida Ruwaida, Gunawan Wicaksono, Muhammad Hidayat Sahid, Febrina Rahmayanti, Florentina Priscilia, Anis Fitriana, Tri Rahayu, Made Susiyanti, Gitalisa Andayani, Anna Puspitasari Bani, Hisar Daniel, Yeni Dwi Lestari Jul 2021

A Multidimensional Welfare Status Of Leprosy Patients Living In A Suburban Area, Yunia Irawati, Sri Linuwih Sw Menaldi, Melinda Harini, Luh Karunia Wahyuni, Wanarani Alwin, Astari Dwiranti, Adhityawarman Menaldi, Sonny Tirta Luzanil, Qaishum Matsurah, Dadun ., Rico Kurniawan, Ida Ruwaida, Gunawan Wicaksono, Muhammad Hidayat Sahid, Febrina Rahmayanti, Florentina Priscilia, Anis Fitriana, Tri Rahayu, Made Susiyanti, Gitalisa Andayani, Anna Puspitasari Bani, Hisar Daniel, Yeni Dwi Lestari

ASEAN Journal of Community Engagement

Leprosy has a high incidence of physical complications that will impact directly the physiological, economic, and social status of patients. Indonesia has a high burden of the disease, and several leprosy settlements are still spread in the country. Neglasari Village, Sitanala, Tangerang serves as one of the places of residence of people who have had leprosy. A health service initiative known as Identifikasi Tanda-Tanda Mata, Ekstremitas, dan Kulit pada Kusta (KATAMATAKU) was launched as a collaboration of health services among multi-departments (ophthalmology, dermatovenereology, and medical rehabilitation). Sitanala has a relatively high incidence of people who have had leprosy with disabilities …


Identifying Health Priorities For A Vulnerable Underserved Population In Uganda, Africa Using Community Base Participatory Research And The Photovoice Approach, Cheryl Wallin Jul 2021

Identifying Health Priorities For A Vulnerable Underserved Population In Uganda, Africa Using Community Base Participatory Research And The Photovoice Approach, Cheryl Wallin

Dissertations

The purpose of this descriptive phenomenological study was to give voice to an underserved and vulnerable population in Uganda, Africa to advocate for health priorities. Nineteen members of the village of Namagera, identified as a leper colony, were selected by community members and volunteered to participate in every element of this study. Descriptive phenomenology was the guiding philosophy and community-based participatory research methods and photovoice provided the lens for social action. Leininger's theory of culture care diversity and universality (Leininger & McFarland, 2006) anchored the study in cultural caring and the community nursing practice model (Parker et al., 2020) kept …


Synthesis Of Small Molecules For The Treatment Of Infectious Diseases, Elena Bray Jul 2021

Synthesis Of Small Molecules For The Treatment Of Infectious Diseases, Elena Bray

USF Tampa Graduate Theses and Dissertations

Drug discovery’s impact on modern healthcare cannot be measured. In the past year, the world has watched scientists all around the globe work together to help protect the public from the novel coronavirus pandemic. Although sometimes slow and costly, drug discovery is important for advancing modern society. Drug discovery is at the core of treating diseases and in particular, infectious diseases. In the first chapter an overview of drug discovery will be discussed in a brief manner.

The second chapter will introduce infectious diseases. In modern society, the development of small molecule treatments for treating bacteria, viruses, and fungi has …


Parasite Infections In Poultry Environments (Case Report On Gallus Domesticus Endoparasite), Phebe Amadea Tanuwijaya, David Febraldo Jul 2021

Parasite Infections In Poultry Environments (Case Report On Gallus Domesticus Endoparasite), Phebe Amadea Tanuwijaya, David Febraldo

Journal of Environmental Science and Sustainable Development

Infection of nematode and cestode worms in chickens can cause decreased egg production, weight loss, growth problems, weakness. The objective of this case study is to look at how an epidemiological approach, clinical symptoms, anatomical pathology investigation, and laboratory testing might help with disease diagnosis. The chicken was found from Banjar Tanggahan Tengah, Bangli, Bali with the type of native chicken (Gallus domesticus), at least 3 months old with the protocol number 369 / N / 20. Samples taken were brain, trachea, lungs, liver, heart, spleen, kidneys, proventriculus, intestines, and feces. Laboratory examinations carried out include histopathology, microbiology, …


Prevalence Of Dementia In Latin America: A Collaborative Study Of Population-Based Cohorts, Ricardo Nitrini, Cássio M. C. Bottino, Cecilia Albala, Nilton Santos Custodio Capuñay, Carlos Ketzoian, Juan J. Llibre Rodriguez, Gladys E. Maestre, Ana Teresa A. Ramos-Cerqueira Jul 2021

Prevalence Of Dementia In Latin America: A Collaborative Study Of Population-Based Cohorts, Ricardo Nitrini, Cássio M. C. Bottino, Cecilia Albala, Nilton Santos Custodio Capuñay, Carlos Ketzoian, Juan J. Llibre Rodriguez, Gladys E. Maestre, Ana Teresa A. Ramos-Cerqueira

School of Medicine Publications

Background:

Dementia is becoming a major public health problem in Latin America (LA), yet epidemiological information on dementia remains scarce in this region. This study analyzes data from epidemiological studies on the prevalence of dementia in LA and compares the prevalence of dementia and its causes across countries in LA and attempts to clarify differences from those of developed regions of the world.

Methods:

A database search for population studies on rates of dementia in LA was performed. Abstracts were also included in the search. Authors of the publications were invited to participate in this collaborative study by sharing missing …


The List: Proverbs For Calculus, Bruce H. Pourciau Jul 2021

The List: Proverbs For Calculus, Bruce H. Pourciau

Journal of Humanistic Mathematics

Topics chosen from first-year calculus illustrate a number of “sayings” or “proverbs,” the first three, for example, being: be awed, like a child; meaning before truth; and act with intention. Many are proverbs for life as well as mathematics.


The Power Of A Double Take: Doubling Back To Show Growth In A Pandemic, Lawrence M. Lesser Jul 2021

The Power Of A Double Take: Doubling Back To Show Growth In A Pandemic, Lawrence M. Lesser

Journal of Humanistic Mathematics

The COVID-19 pandemic inspired reflections on the importance and challenges of teaching exponential growth, such as doubling, to varied audiences.


A Pattern Language For Environmental Justice: Applying Interconnected, Evidence-Based Problem-Solution Sequences To Comprehensive Equity Analysis, Josh Rosa Jul 2021

A Pattern Language For Environmental Justice: Applying Interconnected, Evidence-Based Problem-Solution Sequences To Comprehensive Equity Analysis, Josh Rosa

Cities and the Environment (CATE)

This essay examines pattern language design as a method of comprehensive environmental justice analysis. First, the essay describes common limitations of conventional methods of analysis, finding the interconnected problem-solution sequences described as pattern languages address most limitations. Next, the essay examines the potential for pattern language design, when paired with other methods, to equip local communities to more intelligently evaluate the actual equity impacts of environmental choices.


"What Keeps Me Awake At Night": Assisted Living Administrator Responses To Covid-19., Jason Z. Kyler-Yano, Ozcan Tunalilar, Serena B. Hasworth, Jacklyn N. Kohon, Jaclyn M. Winfree, Riley A. Wilton, Aliza Tuttle, Paula C. Carder Jul 2021

"What Keeps Me Awake At Night": Assisted Living Administrator Responses To Covid-19., Jason Z. Kyler-Yano, Ozcan Tunalilar, Serena B. Hasworth, Jacklyn N. Kohon, Jaclyn M. Winfree, Riley A. Wilton, Aliza Tuttle, Paula C. Carder

Institute on Aging Publications

Assisted living (AL) constitutes an important sector of residential long-term care, yet there has been limited research about the impact of the coronavirus disease 2019 (COVID-19) pandemic in this setting. This qualitative study sought to understand the impact of the early stages of the pandemic (February-August 2020) from AL administrators' perspectives.


A Prospective Cross-Sectional Study Of Tuberculosis In Elderly Hispanics Reveals That Bcg Vaccination At Birth Is Protective Whereas Diabetes Is Not A Risk Factor, Julia M. Scordo, Genesis P. Aguillón-Durán, Doris Ayala, Ana P. Quirino-Cerrillo, Eminé Rodriguez-Reyna, Francisco Mora-Guzmán Dr, Jose A. Caso, Eder Ledezma-Campos, Larry Schlesinger, Jordi B. Torrelles, Blanca I. Restrepo Jul 2021

A Prospective Cross-Sectional Study Of Tuberculosis In Elderly Hispanics Reveals That Bcg Vaccination At Birth Is Protective Whereas Diabetes Is Not A Risk Factor, Julia M. Scordo, Genesis P. Aguillón-Durán, Doris Ayala, Ana P. Quirino-Cerrillo, Eminé Rodriguez-Reyna, Francisco Mora-Guzmán Dr, Jose A. Caso, Eder Ledezma-Campos, Larry Schlesinger, Jordi B. Torrelles, Blanca I. Restrepo

School of Medicine Publications

Background: Aging increases the risk of tuberculosis (TB) and its adverse outcomes, but most studies are based on secondary analyses, and few are in Hispanics. Diabetes is a risk factor for TB in adults, but its contribution in the elderly is unknown. We aimed to identify the role of diabetes and other risk factors for TB in elderly Hispanics.

Methods: Cross-sectional study among newly-diagnosed TB patients, recent contacts (ReC), or community controls (CoC) totaling 646 participants, including 183 elderly (>60 years; 43 TB, 80 ReC, 60 CoC) and 463 adults (18 to 50 years; 80 TB, 301 ReC and …


Foreword From Handling Editor – 9th Edition, Salfia Rahmawati Jul 2021

Foreword From Handling Editor – 9th Edition, Salfia Rahmawati

ASEAN Journal of Community Engagement

We are delighted to present the 9th edition of AJCE, published in July 2021. We have selected eight of the best articles for this edition, consisted of Research Articles.


A Narrative Review On The Unexplored Potential Of Colostrum As A Preventative Treatment And Therapy For Diarrhea In Neonatal Dairy Calves, Havelah S. M. Carter, David L. Renaud, Michael A. Steele, Amanda J. Fischer-Tlustos, Joao H. C. Costa Jul 2021

A Narrative Review On The Unexplored Potential Of Colostrum As A Preventative Treatment And Therapy For Diarrhea In Neonatal Dairy Calves, Havelah S. M. Carter, David L. Renaud, Michael A. Steele, Amanda J. Fischer-Tlustos, Joao H. C. Costa

Animal and Food Sciences Faculty Publications

Diarrhea is the leading cause of morbidity and mortality in pre-weaned dairy calves and, as such, represents a significant animal health and welfare concern. Furthermore, digestive disease early in life is associated with several long-term consequences such as reduced growth rate and decreased milk yield during the first lactation, thus generating severe economic losses. The majority of diarrheic cases in young calves are treated with antimicrobials; however, it is necessary to develop alternative treatments, as excessive antimicrobial usage can lead to antimicrobial resistance and can negatively impact the gut microflora of a calf. Bovine colostrum is abundant in immune and …


Trichomonas Vaginalis Detection In Urogenital Specimens From Symptomatic And Asymptomatic Men And Women Using The Cobas Tv/Mg Test, Barbara Van Der Pol, Arundhati Rao, Melinda B. Nye, Steven Chavoustie, Aaron Ermel, Clair Kaplan, David Eisenberg, Philip A. Chan, Leandro Mena, Sixto Pacheco, Ken B. Waites, Li Xiao, Smitha Krishnamurthy, Ruchika Mohan, Rasa Bertuzis, Chris L. Mcgowin, Rodney Arcenas, Elizabeth M. Marlowe, Stephanie N. Taylor Jul 2021

Trichomonas Vaginalis Detection In Urogenital Specimens From Symptomatic And Asymptomatic Men And Women Using The Cobas Tv/Mg Test, Barbara Van Der Pol, Arundhati Rao, Melinda B. Nye, Steven Chavoustie, Aaron Ermel, Clair Kaplan, David Eisenberg, Philip A. Chan, Leandro Mena, Sixto Pacheco, Ken B. Waites, Li Xiao, Smitha Krishnamurthy, Ruchika Mohan, Rasa Bertuzis, Chris L. Mcgowin, Rodney Arcenas, Elizabeth M. Marlowe, Stephanie N. Taylor

School of Medicine Faculty Publications

Trichomonas vaginalis is a prevalent sexually transmitted infection (STI). Diagnosis has historically relied on either microscopic analysis or culture, the latter being the previous gold standard. However, these tests are not readily available for male diagnosis, generally only perform well for symptomatic women, and are not as sensitive as nucleic acid amplification tests (NAATs). Men are largely asymptomatic but carry the organism and transmit to their sexual partners. This multicenter, prospective study evaluated the performance of the cobas T. vaginalis/Mycoplasma genitalium (TV/MG) assay for detection of T. vaginalis DNA compared with patient infection status (PIS) defined by a combination of …


African Swine Fever Virus Cd2v Protein Induces Β-Interferon Expression And Apoptosis In Swine Peripheral Blood Mononuclear Cells, Sabal Chaulangain, Gustavo A. Delhon, Sushil Khatiwada, Daniel L. Rock Jul 2021

African Swine Fever Virus Cd2v Protein Induces Β-Interferon Expression And Apoptosis In Swine Peripheral Blood Mononuclear Cells, Sabal Chaulangain, Gustavo A. Delhon, Sushil Khatiwada, Daniel L. Rock

School of Veterinary and Biomedical Sciences: Faculty Publications

African swine fever (ASF) is a hemorrhagic disease of swine characterized by massive lymphocyte depletion in lymphoid tissues due to the apoptosis of B and T cells, a process likely triggered by factors released or secreted by infected macrophages. ASFV CD2v (EP402R) has been implicated in viral virulence and immunomodulation in vitro; however, its actual function(s) remains unknown. We found that CD2v expression in swine PK15 cells induces NF-κB-dependent IFN-β and ISGs transcription and an antiviral state. Similar results were observed for CD2v protein treated swine PBMCs and macrophages, the major ASFV target cell. Notably, treatment of swine PBMCs and …


Predicting The Environmental Suitability For Onchocerciasis In Africa As An Aid To Elimination Planning, Elizabeth A. Cromwell, Joshua C P. Osborne, Thomas R. Unnasch, Maria-Gloria Basáñez, Katherine M. Gass, Kira A. Barbre, Elex Hill, Kimberly B. Johnson, Katie M. Donkers, Zulfiqar Ahmed Bhutta Jul 2021

Predicting The Environmental Suitability For Onchocerciasis In Africa As An Aid To Elimination Planning, Elizabeth A. Cromwell, Joshua C P. Osborne, Thomas R. Unnasch, Maria-Gloria Basáñez, Katherine M. Gass, Kira A. Barbre, Elex Hill, Kimberly B. Johnson, Katie M. Donkers, Zulfiqar Ahmed Bhutta

Centre of Excellence in Women and Child Health

Recent evidence suggests that, in some foci, elimination of onchocerciasis from Africa may be feasible with mass drug administration (MDA) of ivermectin. To achieve continental elimination of transmission, mapping surveys will need to be conducted across all implementation units (IUs) for which endemicity status is currently unknown. Using boosted regression tree models with optimised hyperparameter selection, we estimated environmental suitability for onchocerciasis at the 5 × 5-km resolution across Africa. In order to classify IUs that include locations that are environmentally suitable, we used receiver operating characteristic (ROC) analysis to identify an optimal threshold for suitability concordant with locations where …


Promoting Prep Uptake In Primary Care Practice For The Prevention Of Hiv Transmissions, Sokonie S. Reed Jul 2021

Promoting Prep Uptake In Primary Care Practice For The Prevention Of Hiv Transmissions, Sokonie S. Reed

Dissertations

The nation is charged with the great task of eradicating human immunodeficiency virus (HIV) by year 2030. PrEP is an acronym for pre-exposure prophylaxis. Multiple clinical trials have recognized it as a safe and highly effective regimen that includes taking a daily dose of an antiretroviral medication to prevent HIV transmissions. The regimen is backed by prominent healthcare organizations like the Centers for Disease Control and Prevention (CDC) that have developed guidelines for PrEP implementation. Yet, there is a nationwide problem of low provider uptake of PrEP. Investigators in the literature on PrEP implementation concur that PrEP, as a preventative …


Single-Particle Characterization Of Sars-Cov-2 Isoelectric Point And Comparison To Variants Of Interest, Oluwatoyin Areo, Pratik U. Joshi, Mark Obrenovich, Moncef Tayahi, Caryn L. Heldt Jul 2021

Single-Particle Characterization Of Sars-Cov-2 Isoelectric Point And Comparison To Variants Of Interest, Oluwatoyin Areo, Pratik U. Joshi, Mark Obrenovich, Moncef Tayahi, Caryn L. Heldt

Michigan Tech Publications, Part 1

SARS-CoV-2, the cause of COVID-19, is a new, highly pathogenic coronavirus, which is the third coronavirus to emerge in the past 2 decades and the first to become a global pandemic. The virus has demonstrated itself to be extremely transmissible and deadly. Recent data suggest that a targeted approach is key to mitigating infectivity. Due to the proliferation of cataloged protein and nucleic acid sequences in databases, the function of the nucleic acid, and genetic encoded proteins, we make predictions by simply aligning sequences and exploring their homology. Thus, similar amino acid sequences in a protein usually confer similar biochemical …


Poliovirus Excretion Among Children With Primary Immune Deficiency In Pakistan: A Pilot Surveillance Study Protocol, Asma Sadruddin Pethani, Zaubina Kazi, Ujala Nayyar, Muhammad Shafiq-Ur-Rehman, Mohammad Tahir Yousafzai, Mach Ondrej, Ali Faisal Saleem Jul 2021

Poliovirus Excretion Among Children With Primary Immune Deficiency In Pakistan: A Pilot Surveillance Study Protocol, Asma Sadruddin Pethani, Zaubina Kazi, Ujala Nayyar, Muhammad Shafiq-Ur-Rehman, Mohammad Tahir Yousafzai, Mach Ondrej, Ali Faisal Saleem

Department of Paediatrics and Child Health

Introduction: Children with primary immunodeficiency disorders (PID) are more susceptible to developing viral infections and are at a substantially increased risk of developing paralytic poliomyelitis. Such children, if given oral polio vaccines tend to excrete poliovirus chronically that may lead to the propagation of highly divergent vaccine-derived poliovirus (VDPV). Consequently, they may act as a reservoir for the community by introducing an altered virus potentially imposing a risk to global polio eradication. However, the risks of chronic and prolonged excretion are not well characterised in the study context. This study seeks to establish a pilot surveillance system for successful identification …


The Nexus Of Climate Change, Covid-19, And Environmental Justice On Children's Health, Emma Pennea, Laura Anderko, Caroline Moore, Ruth Mcdermott-Levy Jul 2021

The Nexus Of Climate Change, Covid-19, And Environmental Justice On Children's Health, Emma Pennea, Laura Anderko, Caroline Moore, Ruth Mcdermott-Levy

Journal of Applied Research on Children: Informing Policy for Children at Risk

Climate change poses a threat to children, who are increasingly vulnerable, depending on adults to protect them from the impacts of these changes including extreme weather events, poor air and water quality and risk to mental health. Children living in poverty carry additional burdens and risks, living in environments that consistently experience poor air and water quality from polluting industries, compounded by the effects of climate change. COVID-19 has placed additional challenges to children’s health and increases the complexity of addressing climate change and environmental justice. The intersection between climate change and COVID-19 exacerbates these existing disparities by impacting children's …